2E08A

Crystal structure of glu140 to lys mutant of diphthine synthase
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPKGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords Probable diphthine synthase
total genus 82
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-10-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2e08A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2e08A01
2E8HA 2DSHA 2DV3A 2EGSA 2P6IA 2E8RA 2QBUA 2E8SA 2E08A 2E4NA 2ED5A 3KWPA 1S4DA 2EN5A 2PB6A 2Z6RA 3HH1A 1WNGA 1VCEA 2EJJA 2BB3A 2PCHA 3ND1A 3NEIA 2HUQA 2DEKA 2E4RA 2YBOA 3FQ6A 2P6DA 1VA0A 2DV4A 2EJZA 2EK7A 2OWFA 2P5FA 2EEQA 2EHLA 1CBFA 2P6LA 2PCIA 2EL0A 2E07A 2E16A 2PB4A 2OWGA 2EHCA 2ELDA 2EK4A 1PJQA 1PJTA 2E0NA 2HUXA 2P5CA 2ENIA 2E0KA 2PCMA 2PCAA 3I4TA 2HUVA 2EK2A 2P6KA 2P9DA 2P2XA 2ELEA 5HW4A 2E15A 2HR8A 2YBQA 2CBFA 2PCGA 2DXWA 2EH5A 2EL2A 2EK3A 2EL1A 2EKAA 2ED3A 2EGBA 2EL3A 2HUTA 2DV7A 3NUTA 2OWUA 2DSGA 4E16A 2ZVCA 1PJSA 3NDCA 2E17A 2E8QA 2EJKA 1WYZA 2DSIA 2PB5A 1V9AA 2EH4A 2E7RA 2NPNA 2EH2A 2EMUA 2OWKA 2EGLA 1VE2A 2EMRA 2DXXA 2DV5A 2DXVA 2PCKA 2ZVBA 1WDEA 2OWVA 1VHVA 3FFYA
chains in the Genus database with same CATH superfamily
2E8HA 2DSHA 2DV3A 2EGSA 2P6IA 3ZGLA 3LMMA 2E8RA 2QBUA 2E8SA 2E08A 3TIXB 2E4NA 2ED5A 3KWPA 3T0FA 1S4DA 2EN5A 2PB6A 2Z6RA 3HH1A 1WNGA 1VCEA 3SZLA 2EJJA 4H4CA 2BB3A 2PCHA 3T0GA 3ND1A 3KE9A 3UV3A 3NEIA 2HUQA 3SZOA 2DEKA 4MUYA 2E4RA 2YBOA 3FQ6A 4MV5A 3DNFA 2P6DA 1VA0A 2DV4A 3URKA 2EJZA 2EK7A 2OWFA 2P5FA 3UWMA 3KEMA 2EEQA 2EHLA 1CBFA 2P6LA 2PCIA 2EL0A 2E07A 2E16A 3SZUA 2PB4A 2OWGA 3UTDA 2EHCA 2ELDA 2EK4A 1PJQA 4EB3A 1PJTA 2E0NA 2HUXA 2P5CA 2ENIA 2E0KA 2PCMA 2PCAA 3I4TA 2HUVA 3UV7A 2EK2A 2P6KA 2P9DA 2P2XA 2ELEA 5HW4A 2E15A 2HR8A 2YBQA 2CBFA 2PCGA 2DXWA 2EH5A 2EL2A 4MUXA 4H4DA 2EK3A 3UTCA 4H4EA 4MV0A 2EL1A 2EKAA 2ED3A 2EGBA 2EL3A 2HUTA 2DV7A 3NUTA 2OWUA 2DSGA 4E16A 2ZVCA 1PJSA 3NDCA 2E17A 2E8QA 2EJKA 1WYZA 2DSIA 2PB5A 1V9AA 2EH4A 3KE8A 2E7RA 3UV6A 3KEFA 2KYYA 2NPNA 3F7TA 2EH2A 2EMUA 2OWKA 2EGLA 1VE2A 2EMRA 3KELA 3ZGNA 2DXXA 2DV5A 4N7BA 2DXVA 2PCKA 2ZVBA 1WDEA 2OWVA 1VHVA 3FFYA
chains in the Genus database with same CATH topology
2E8HA 2DSHA 2DV3A 2EGSA 2P6IA 3ZGLA 3LMMA 2E8RA 2QBUA 2E8SA 2E08A 3TIXB 2E4NA 2ED5A 3KWPA 3T0FA 1S4DA 2EN5A 2PB6A 2Z6RA 3HH1A 1WNGA 1VCEA 3SZLA 2EJJA 4H4CA 2BB3A 2PCHA 3T0GA 3ND1A 3KE9A 3UV3A 3NEIA 2HUQA 3SZOA 2DEKA 4MUYA 2E4RA 2YBOA 3FQ6A 4MV5A 3DNFA 2P6DA 1VA0A 2DV4A 3URKA 2EJZA 2EK7A 2OWFA 2P5FA 3UWMA 3KEMA 2EEQA 2EHLA 1CBFA 2P6LA 2PCIA 2EL0A 2E07A 2E16A 3SZUA 2PB4A 2OWGA 3UTDA 2EHCA 2ELDA 2EK4A 1PJQA 4EB3A 1PJTA 2E0NA 2HUXA 2P5CA 2ENIA 2E0KA 2PCMA 2PCAA 3I4TA 2HUVA 3UV7A 2EK2A 2P6KA 2P9DA 2P2XA 2ELEA 5HW4A 2E15A 2HR8A 2YBQA 2CBFA 2PCGA 2DXWA 2EH5A 2EL2A 4MUXA 4H4DA 2EK3A 3UTCA 4H4EA 4MV0A 2EL1A 2EKAA 2ED3A 2EGBA 2EL3A 2HUTA 2DV7A 3NUTA 2OWUA 2DSGA 4E16A 2ZVCA 1PJSA 3NDCA 2E17A 2E8QA 2EJKA 1WYZA 2DSIA 2PB5A 1V9AA 2EH4A 3KE8A 2E7RA 3UV6A 3KEFA 2KYYA 2NPNA 3F7TA 2EH2A 2EMUA 2OWKA 2EGLA 1VE2A 2EMRA 3KELA 3ZGNA 2DXXA 2DV5A 4N7BA 2DXVA 2PCKA 2ZVBA 1WDEA 2OWVA 1VHVA 3FFYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E8H A;  2DSH A;  2DV3 A;  2EGS A;  2P6I A;  2E8R A;  2QBU A;  2E8S A;  2E08 A;  2E4N A;  2ED5 A;  3KWP A;  1S4D A;  2EN5 A;  2PB6 A;  2Z6R A;  3HH1 A;  1WNG A;  1VCE A;  2EJJ A;  2BB3 A;  2PCH A;  3ND1 A;  3NEI A;  2HUQ A;  2DEK A;  2E4R A;  2YBO A;  3FQ6 A;  2P6D A;  1VA0 A;  2DV4 A;  2EJZ A;  2EK7 A;  2OWF A;  2P5F A;  2EEQ A;  2EHL A;  1CBF A;  2P6L A;  2PCI A;  2EL0 A;  2E07 A;  2E16 A;  2PB4 A;  2OWG A;  2EHC A;  2ELD A;  2EK4 A;  1PJQ A;  1PJT A;  2E0N A;  2HUX A;  2P5C A;  2ENI A;  2E0K A;  2PCM A;  2PCA A;  3I4T A;  2HUV A;  2EK2 A;  2P6K A;  2P9D A;  2P2X A;  2ELE A;  5HW4 A;  2E15 A;  2HR8 A;  2YBQ A;  2CBF A;  2PCG A;  2DXW A;  2EH5 A;  2EL2 A;  2EK3 A;  2EL1 A;  2EKA A;  2ED3 A;  2EGB A;  2EL3 A;  2HUT A;  2DV7 A;  3NUT A;  2OWU A;  2DSG A;  4E16 A;  2ZVC A;  1PJS A;  3NDC A;  2E17 A;  2E8Q A;  2EJK A;  1WYZ A;  2DSI A;  2PB5 A;  1V9A A;  2EH4 A;  2E7R A;  2NPN A;  2EH2 A;  2EMU A;  2OWK A;  2EGL A;  1VE2 A;  2EMR A;  2DXX A;  2DV5 A;  2DXV A;  2PCK A;  2ZVB A;  1WDE A;  2OWV A;  1VHV A;  3FFY A; 
#chains in the Genus database with same CATH topology
 2E8H A;  2DSH A;  2DV3 A;  2EGS A;  2P6I A;  3ZGL A;  3LMM A;  2E8R A;  2QBU A;  2E8S A;  2E08 A;  3TIX B;  2E4N A;  2ED5 A;  3KWP A;  3T0F A;  1S4D A;  2EN5 A;  2PB6 A;  2Z6R A;  3HH1 A;  1WNG A;  1VCE A;  3SZL A;  2EJJ A;  4H4C A;  2BB3 A;  2PCH A;  3T0G A;  3ND1 A;  3KE9 A;  3UV3 A;  3NEI A;  2HUQ A;  3SZO A;  2DEK A;  4MUY A;  2E4R A;  2YBO A;  3FQ6 A;  4MV5 A;  3DNF A;  2P6D A;  1VA0 A;  2DV4 A;  3URK A;  2EJZ A;  2EK7 A;  2OWF A;  2P5F A;  3UWM A;  3KEM A;  2EEQ A;  2EHL A;  1CBF A;  2P6L A;  2PCI A;  2EL0 A;  2E07 A;  2E16 A;  3SZU A;  2PB4 A;  2OWG A;  3UTD A;  2EHC A;  2ELD A;  2EK4 A;  1PJQ A;  4EB3 A;  1PJT A;  2E0N A;  2HUX A;  2P5C A;  2ENI A;  2E0K A;  2PCM A;  2PCA A;  3I4T A;  2HUV A;  3UV7 A;  2EK2 A;  2P6K A;  2P9D A;  2P2X A;  2ELE A;  5HW4 A;  2E15 A;  2HR8 A;  2YBQ A;  2CBF A;  2PCG A;  2DXW A;  2EH5 A;  2EL2 A;  4MUX A;  4H4D A;  2EK3 A;  3UTC A;  4H4E A;  4MV0 A;  2EL1 A;  2EKA A;  2ED3 A;  2EGB A;  2EL3 A;  2HUT A;  2DV7 A;  3NUT A;  2OWU A;  2DSG A;  4E16 A;  2ZVC A;  1PJS A;  3NDC A;  2E17 A;  2E8Q A;  2EJK A;  1WYZ A;  2DSI A;  2PB5 A;  1V9A A;  2EH4 A;  3KE8 A;  2E7R A;  3UV6 A;  3KEF A;  2KYY A;  2NPN A;  3F7T A;  2EH2 A;  2EMU A;  2OWK A;  2EGL A;  1VE2 A;  2EMR A;  3KEL A;  3ZGN A;  2DXX A;  2DV5 A;  4N7B A;  2DXV A;  2PCK A;  2ZVB A;  1WDE A;  2OWV A;  1VHV A;  3FFY A; 
#chains in the Genus database with same CATH homology
 2E8H A;  2DSH A;  2DV3 A;  2EGS A;  2P6I A;  3ZGL A;  3LMM A;  2E8R A;  2QBU A;  2E8S A;  2E08 A;  3TIX B;  2E4N A;  2ED5 A;  3KWP A;  3T0F A;  1S4D A;  2EN5 A;  2PB6 A;  2Z6R A;  3HH1 A;  1WNG A;  1VCE A;  3SZL A;  2EJJ A;  4H4C A;  2BB3 A;  2PCH A;  3T0G A;  3ND1 A;  3KE9 A;  3UV3 A;  3NEI A;  2HUQ A;  3SZO A;  2DEK A;  4MUY A;  2E4R A;  2YBO A;  3FQ6 A;  4MV5 A;  3DNF A;  2P6D A;  1VA0 A;  2DV4 A;  3URK A;  2EJZ A;  2EK7 A;  2OWF A;  2P5F A;  3UWM A;  3KEM A;  2EEQ A;  2EHL A;  1CBF A;  2P6L A;  2PCI A;  2EL0 A;  2E07 A;  2E16 A;  3SZU A;  2PB4 A;  2OWG A;  3UTD A;  2EHC A;  2ELD A;  2EK4 A;  1PJQ A;  4EB3 A;  1PJT A;  2E0N A;  2HUX A;  2P5C A;  2ENI A;  2E0K A;  2PCM A;  2PCA A;  3I4T A;  2HUV A;  3UV7 A;  2EK2 A;  2P6K A;  2P9D A;  2P2X A;  2ELE A;  5HW4 A;  2E15 A;  2HR8 A;  2YBQ A;  2CBF A;  2PCG A;  2DXW A;  2EH5 A;  2EL2 A;  4MUX A;  4H4D A;  2EK3 A;  3UTC A;  4H4E A;  4MV0 A;  2EL1 A;  2EKA A;  2ED3 A;  2EGB A;  2EL3 A;  2HUT A;  2DV7 A;  3NUT A;  2OWU A;  2DSG A;  4E16 A;  2ZVC A;  1PJS A;  3NDC A;  2E17 A;  2E8Q A;  2EJK A;  1WYZ A;  2DSI A;  2PB5 A;  1V9A A;  2EH4 A;  3KE8 A;  2E7R A;  3UV6 A;  3KEF A;  2KYY A;  2NPN A;  3F7T A;  2EH2 A;  2EMU A;  2OWK A;  2EGL A;  1VE2 A;  2EMR A;  3KEL A;  3ZGN A;  2DXX A;  2DV5 A;  4N7B A;  2DXV A;  2PCK A;  2ZVB A;  1WDE A;  2OWV A;  1VHV A;  3FFY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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