2E08A

Crystal structure of glu140 to lys mutant of diphthine synthase
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
265
structure length
265
Chain Sequence
b'MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPKGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Probable diphthine synthase
publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
total genus 82
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-10-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2e08A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2e08A01
2P6IA 1PJTA 2EH4A 2OWVA 2EMRA 2PB6A 3KWPA 1VA0A 2DXXA 1V9AA 2E8SA 1WNGA 2E0NA 2E15A 2E0KA 2E8RA 1VHVA 2EGBA 2EK3A 2P6LA 2HUXA 3NDCA 2EMUA 2EN5A 3I4TA 2ZVBA 2PCGA 2DV7A 2PCKA 2E4NA 2ED3A 2EKAA 2HUQA 2EJZA 2PCHA 3NUTA 1PJSA 2YBOA 2Z6RA 3FFYA 2EL0A 2PCAA 2E4RA 2E16A 2DV3A 2EGSA 2E17A 2QBUA 2ED5A 2EK4A 2BB3A 2EHLA 5HW4A 2P2XA 2CBFA 2EK2A 2E07A 2EHCA 2OWGA 2OWFA 2EK7A 2EJKA 1S4DA 3NEIA 2DSGA 2DV4A 2EGLA 2EH5A 2HUTA 2E08A 2OWKA 2DV5A 2HR8A 2EL1A 2DXWA 1WDEA 3FQ6A 2P6KA 2EEQA 1PJQA 2NPNA 2PCMA 1WYZA 2EH2A 2ENIA 2P6DA 1CBFA 2DSIA 2DXVA 2P5FA 2EL2A 1VCEA 2DEKA 1VE2A 2PB5A 4E16A 2ELDA 2PCIA 2HUVA 2YBQA 2DSHA 2EL3A 2ELEA 3HH1A 2E8QA 2E8HA 2PB4A 2P9DA 2E7RA 2P5CA 2EJJA 2OWUA 2ZVCA 3ND1A
chains in the Genus database with same CATH superfamily
2P6IA 1PJTA 3URKA 2EH4A 2OWVA 2KYYA 2EMRA 4MV0A 3KEFA 3T0FA 3DNFA 2PB6A 3KWPA 1VA0A 2DXXA 1V9AA 2E8SA 1WNGA 2E0NA 2E15A 2E0KA 2E8RA 1VHVA 2EGBA 2EK3A 2P6LA 2HUXA 4N7BA 3TIXB 3NDCA 4MUYA 2EMUA 2EN5A 3I4TA 2ZVBA 4H4CA 2PCGA 2DV7A 2PCKA 2E4NA 2ED3A 2EKAA 3F7TA 2HUQA 2EJZA 2PCHA 3NUTA 3UV7A 1PJSA 2YBOA 2Z6RA 3FFYA 2EL0A 2PCAA 2E4RA 3LMMA 3KEMA 2E16A 3ZGNA 4EB3A 2DV3A 2EGSA 4H4EA 2E17A 2QBUA 3UTCA 2ED5A 2EK4A 2BB3A 2EHLA 3UTDA 5HW4A 2P2XA 3KE8A 2CBFA 2EK2A 4MUXA 2E07A 2EHCA 3SZOA 4H4DA 2OWGA 2OWFA 2EK7A 3KELA 2EJKA 1S4DA 3NEIA 2DSGA 2DV4A 2EGLA 2EH5A 2HUTA 2E08A 2OWKA 2DV5A 2HR8A 2EL1A 2DXWA 3T0GA 1WDEA 3UV3A 3FQ6A 2P6KA 2EEQA 1PJQA 2NPNA 2PCMA 1WYZA 2EH2A 2ENIA 2P6DA 3ZGLA 1CBFA 2DSIA 2DXVA 2P5FA 2EL2A 1VCEA 2DEKA 3KE9A 1VE2A 3SZUA 3UWMA 2PB5A 4E16A 2ELDA 2PCIA 2HUVA 2YBQA 2DSHA 2EL3A 2ELEA 3HH1A 4MV5A 2E8QA 2E8HA 2PB4A 3SZLA 2P9DA 2E7RA 2P5CA 3UV6A 2EJJA 2OWUA 2ZVCA 3ND1A
chains in the Genus database with same CATH topology
2P6IA 1PJTA 3URKA 2EH4A 2OWVA 2KYYA 2EMRA 4MV0A 3KEFA 3T0FA 3DNFA 2PB6A 3KWPA 1VA0A 2DXXA 1V9AA 2E8SA 1WNGA 2E0NA 2E15A 2E0KA 2E8RA 1VHVA 2EGBA 2EK3A 2P6LA 2HUXA 4N7BA 3TIXB 3NDCA 4MUYA 2EMUA 2EN5A 3I4TA 2ZVBA 4H4CA 2PCGA 2DV7A 2PCKA 2E4NA 2ED3A 2EKAA 3F7TA 2HUQA 2EJZA 2PCHA 3NUTA 3UV7A 1PJSA 2YBOA 2Z6RA 3FFYA 2EL0A 2PCAA 2E4RA 3LMMA 3KEMA 2E16A 3ZGNA 4EB3A 2DV3A 2EGSA 4H4EA 2E17A 2QBUA 3UTCA 2ED5A 2EK4A 2BB3A 2EHLA 3UTDA 5HW4A 2P2XA 3KE8A 2CBFA 2EK2A 4MUXA 2E07A 2EHCA 3SZOA 4H4DA 2OWGA 2OWFA 2EK7A 3KELA 2EJKA 1S4DA 3NEIA 2DSGA 2DV4A 2EGLA 2EH5A 2HUTA 2E08A 2OWKA 2DV5A 2HR8A 2EL1A 2DXWA 3T0GA 1WDEA 3UV3A 3FQ6A 2P6KA 2EEQA 1PJQA 2NPNA 2PCMA 1WYZA 2EH2A 2ENIA 2P6DA 3ZGLA 1CBFA 2DSIA 2DXVA 2P5FA 2EL2A 1VCEA 2DEKA 3KE9A 1VE2A 3SZUA 3UWMA 2PB5A 4E16A 2ELDA 2PCIA 2HUVA 2YBQA 2DSHA 2EL3A 2ELEA 3HH1A 4MV5A 2E8QA 2E8HA 2PB4A 3SZLA 2P9DA 2E7RA 2P5CA 3UV6A 2EJJA 2OWUA 2ZVCA 3ND1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P6I A;  1PJT A;  2EH4 A;  2OWV A;  2EMR A;  2PB6 A;  3KWP A;  1VA0 A;  2DXX A;  1V9A A;  2E8S A;  1WNG A;  2E0N A;  2E15 A;  2E0K A;  2E8R A;  1VHV A;  2EGB A;  2EK3 A;  2P6L A;  2HUX A;  3NDC A;  2EMU A;  2EN5 A;  3I4T A;  2ZVB A;  2PCG A;  2DV7 A;  2PCK A;  2E4N A;  2ED3 A;  2EKA A;  2HUQ A;  2EJZ A;  2PCH A;  3NUT A;  1PJS A;  2YBO A;  2Z6R A;  3FFY A;  2EL0 A;  2PCA A;  2E4R A;  2E16 A;  2DV3 A;  2EGS A;  2E17 A;  2QBU A;  2ED5 A;  2EK4 A;  2BB3 A;  2EHL A;  5HW4 A;  2P2X A;  2CBF A;  2EK2 A;  2E07 A;  2EHC A;  2OWG A;  2OWF A;  2EK7 A;  2EJK A;  1S4D A;  3NEI A;  2DSG A;  2DV4 A;  2EGL A;  2EH5 A;  2HUT A;  2E08 A;  2OWK A;  2DV5 A;  2HR8 A;  2EL1 A;  2DXW A;  1WDE A;  3FQ6 A;  2P6K A;  2EEQ A;  1PJQ A;  2NPN A;  2PCM A;  1WYZ A;  2EH2 A;  2ENI A;  2P6D A;  1CBF A;  2DSI A;  2DXV A;  2P5F A;  2EL2 A;  1VCE A;  2DEK A;  1VE2 A;  2PB5 A;  4E16 A;  2ELD A;  2PCI A;  2HUV A;  2YBQ A;  2DSH A;  2EL3 A;  2ELE A;  3HH1 A;  2E8Q A;  2E8H A;  2PB4 A;  2P9D A;  2E7R A;  2P5C A;  2EJJ A;  2OWU A;  2ZVC A;  3ND1 A; 
#chains in the Genus database with same CATH topology
 2P6I A;  1PJT A;  3URK A;  2EH4 A;  2OWV A;  2KYY A;  2EMR A;  4MV0 A;  3KEF A;  3T0F A;  3DNF A;  2PB6 A;  3KWP A;  1VA0 A;  2DXX A;  1V9A A;  2E8S A;  1WNG A;  2E0N A;  2E15 A;  2E0K A;  2E8R A;  1VHV A;  2EGB A;  2EK3 A;  2P6L A;  2HUX A;  4N7B A;  3TIX B;  3NDC A;  4MUY A;  2EMU A;  2EN5 A;  3I4T A;  2ZVB A;  4H4C A;  2PCG A;  2DV7 A;  2PCK A;  2E4N A;  2ED3 A;  2EKA A;  3F7T A;  2HUQ A;  2EJZ A;  2PCH A;  3NUT A;  3UV7 A;  1PJS A;  2YBO A;  2Z6R A;  3FFY A;  2EL0 A;  2PCA A;  2E4R A;  3LMM A;  3KEM A;  2E16 A;  3ZGN A;  4EB3 A;  2DV3 A;  2EGS A;  4H4E A;  2E17 A;  2QBU A;  3UTC A;  2ED5 A;  2EK4 A;  2BB3 A;  2EHL A;  3UTD A;  5HW4 A;  2P2X A;  3KE8 A;  2CBF A;  2EK2 A;  4MUX A;  2E07 A;  2EHC A;  3SZO A;  4H4D A;  2OWG A;  2OWF A;  2EK7 A;  3KEL A;  2EJK A;  1S4D A;  3NEI A;  2DSG A;  2DV4 A;  2EGL A;  2EH5 A;  2HUT A;  2E08 A;  2OWK A;  2DV5 A;  2HR8 A;  2EL1 A;  2DXW A;  3T0G A;  1WDE A;  3UV3 A;  3FQ6 A;  2P6K A;  2EEQ A;  1PJQ A;  2NPN A;  2PCM A;  1WYZ A;  2EH2 A;  2ENI A;  2P6D A;  3ZGL A;  1CBF A;  2DSI A;  2DXV A;  2P5F A;  2EL2 A;  1VCE A;  2DEK A;  3KE9 A;  1VE2 A;  3SZU A;  3UWM A;  2PB5 A;  4E16 A;  2ELD A;  2PCI A;  2HUV A;  2YBQ A;  2DSH A;  2EL3 A;  2ELE A;  3HH1 A;  4MV5 A;  2E8Q A;  2E8H A;  2PB4 A;  3SZL A;  2P9D A;  2E7R A;  2P5C A;  3UV6 A;  2EJJ A;  2OWU A;  2ZVC A;  3ND1 A; 
#chains in the Genus database with same CATH homology
 2P6I A;  1PJT A;  3URK A;  2EH4 A;  2OWV A;  2KYY A;  2EMR A;  4MV0 A;  3KEF A;  3T0F A;  3DNF A;  2PB6 A;  3KWP A;  1VA0 A;  2DXX A;  1V9A A;  2E8S A;  1WNG A;  2E0N A;  2E15 A;  2E0K A;  2E8R A;  1VHV A;  2EGB A;  2EK3 A;  2P6L A;  2HUX A;  4N7B A;  3TIX B;  3NDC A;  4MUY A;  2EMU A;  2EN5 A;  3I4T A;  2ZVB A;  4H4C A;  2PCG A;  2DV7 A;  2PCK A;  2E4N A;  2ED3 A;  2EKA A;  3F7T A;  2HUQ A;  2EJZ A;  2PCH A;  3NUT A;  3UV7 A;  1PJS A;  2YBO A;  2Z6R A;  3FFY A;  2EL0 A;  2PCA A;  2E4R A;  3LMM A;  3KEM A;  2E16 A;  3ZGN A;  4EB3 A;  2DV3 A;  2EGS A;  4H4E A;  2E17 A;  2QBU A;  3UTC A;  2ED5 A;  2EK4 A;  2BB3 A;  2EHL A;  3UTD A;  5HW4 A;  2P2X A;  3KE8 A;  2CBF A;  2EK2 A;  4MUX A;  2E07 A;  2EHC A;  3SZO A;  4H4D A;  2OWG A;  2OWF A;  2EK7 A;  3KEL A;  2EJK A;  1S4D A;  3NEI A;  2DSG A;  2DV4 A;  2EGL A;  2EH5 A;  2HUT A;  2E08 A;  2OWK A;  2DV5 A;  2HR8 A;  2EL1 A;  2DXW A;  3T0G A;  1WDE A;  3UV3 A;  3FQ6 A;  2P6K A;  2EEQ A;  1PJQ A;  2NPN A;  2PCM A;  1WYZ A;  2EH2 A;  2ENI A;  2P6D A;  3ZGL A;  1CBF A;  2DSI A;  2DXV A;  2P5F A;  2EL2 A;  1VCE A;  2DEK A;  3KE9 A;  1VE2 A;  3SZU A;  3UWM A;  2PB5 A;  4E16 A;  2ELD A;  2PCI A;  2HUV A;  2YBQ A;  2DSH A;  2EL3 A;  2ELE A;  3HH1 A;  4MV5 A;  2E8Q A;  2E8H A;  2PB4 A;  3SZL A;  2P9D A;  2E7R A;  2P5C A;  3UV6 A;  2EJJ A;  2OWU A;  2ZVC A;  3ND1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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