2E16A

Crystal structure of glu140 to arg mutant of diphthine synthase
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPRGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords Probable diphthine synthase
total genus 82
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-10-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2e16A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2e16A01
2HUVA 2DV3A 2OWUA 2EH2A 2EN5A 2EK7A 2EK4A 2EL1A 2E17A 2DV7A 2P6KA 2E8SA 1S4DA 2Z6RA 2EMUA 2HUXA 2P5FA 2OWFA 2DV5A 2EKAA 2EL0A 2P6IA 2YBQA 2E0KA 2E15A 2ZVBA 2DXVA 2P2XA 2E16A 2EJKA 2PB5A 3I4TA 2EK2A 1VHVA 2E0NA 4E16A 2P9DA 1PJTA 2HUQA 2OWKA 2PB4A 2EGBA 2DSGA 2PCKA 2BB3A 5HW4A 1WYZA 2E8HA 2DXWA 2EL3A 2P6DA 2PCGA 2EGSA 2E8QA 1VE2A 2E4NA 2DEKA 2EK3A 1PJQA 2DXXA 3NUTA 2ENIA 2ED5A 1VA0A 2EEQA 2EJZA 3FFYA 1V9AA 2EGLA 2EHCA 1WDEA 1WNGA 2EMRA 2EJJA 2ELDA 2YBOA 2HUTA 2E07A 2PCAA 2EH5A 1CBFA 2E8RA 2E7RA 2EHLA 2HR8A 2P6LA 1VCEA 2ZVCA 3NEIA 2ED3A 2E08A 3FQ6A 2EH4A 2PB6A 3KWPA 2NPNA 2PCMA 3HH1A 1PJSA 2E4RA 2PCHA 2OWVA 2CBFA 2DSHA 2DV4A 2DSIA 2ELEA 2P5CA 2QBUA 2OWGA 3NDCA 3ND1A 2PCIA 2EL2A
chains in the Genus database with same CATH superfamily
2HUVA 3UV6A 2DV3A 3DNFA 2OWUA 2EH2A 2EN5A 2EK7A 3ZGNA 3KE8A 2EK4A 2EL1A 2E17A 2DV7A 2P6KA 3SZOA 2E8SA 3UWMA 1S4DA 3UV3A 3KEFA 2Z6RA 3TIXB 2EMUA 2HUXA 2P5FA 4MV0A 2OWFA 2DV5A 2EKAA 2EL0A 2P6IA 2YBQA 2E0KA 2E15A 2ZVBA 2DXVA 2P2XA 2E16A 2EJKA 2PB5A 4H4DA 3I4TA 2EK2A 1VHVA 2E0NA 4E16A 2P9DA 1PJTA 2HUQA 4N7BA 3URKA 3SZLA 2OWKA 2PB4A 2EGBA 2DSGA 2PCKA 3KELA 2BB3A 5HW4A 3KE9A 1WYZA 2E8HA 2DXWA 2EL3A 2P6DA 2PCGA 3KEMA 3T0GA 2EGSA 3LMMA 3UTDA 2E8QA 1VE2A 2E4NA 2KYYA 2DEKA 2EK3A 1PJQA 2DXXA 3NUTA 2ENIA 2ED5A 1VA0A 4MUYA 2EEQA 2EJZA 3FFYA 1V9AA 2EGLA 2EHCA 1WDEA 1WNGA 2EMRA 3T0FA 3SZUA 2EJJA 2ELDA 2YBOA 3F7TA 2HUTA 2E07A 2PCAA 2EH5A 1CBFA 2E8RA 2E7RA 2EHLA 2HR8A 2P6LA 3UTCA 1VCEA 4H4CA 3ZGLA 2ZVCA 4MUXA 4EB3A 3NEIA 2ED3A 2E08A 3FQ6A 3UV7A 2EH4A 4H4EA 2PB6A 3KWPA 2NPNA 2PCMA 3HH1A 1PJSA 2E4RA 2PCHA 2OWVA 2CBFA 2DSHA 2DV4A 2DSIA 2ELEA 2P5CA 2QBUA 2OWGA 3NDCA 3ND1A 2PCIA 4MV5A 2EL2A
chains in the Genus database with same CATH topology
2HUVA 3UV6A 2DV3A 3DNFA 2OWUA 2EH2A 2EN5A 2EK7A 3ZGNA 3KE8A 2EK4A 2EL1A 2E17A 2DV7A 2P6KA 3SZOA 2E8SA 3UWMA 1S4DA 3UV3A 3KEFA 2Z6RA 3TIXB 2EMUA 2HUXA 2P5FA 4MV0A 2OWFA 2DV5A 2EKAA 2EL0A 2P6IA 2YBQA 2E0KA 2E15A 2ZVBA 2DXVA 2P2XA 2E16A 2EJKA 2PB5A 4H4DA 3I4TA 2EK2A 1VHVA 2E0NA 4E16A 2P9DA 1PJTA 2HUQA 4N7BA 3URKA 3SZLA 2OWKA 2PB4A 2EGBA 2DSGA 2PCKA 3KELA 2BB3A 5HW4A 3KE9A 1WYZA 2E8HA 2DXWA 2EL3A 2P6DA 2PCGA 3KEMA 3T0GA 2EGSA 3LMMA 3UTDA 2E8QA 1VE2A 2E4NA 2KYYA 2DEKA 2EK3A 1PJQA 2DXXA 3NUTA 2ENIA 2ED5A 1VA0A 4MUYA 2EEQA 2EJZA 3FFYA 1V9AA 2EGLA 2EHCA 1WDEA 1WNGA 2EMRA 3T0FA 3SZUA 2EJJA 2ELDA 2YBOA 3F7TA 2HUTA 2E07A 2PCAA 2EH5A 1CBFA 2E8RA 2E7RA 2EHLA 2HR8A 2P6LA 3UTCA 1VCEA 4H4CA 3ZGLA 2ZVCA 4MUXA 4EB3A 3NEIA 2ED3A 2E08A 3FQ6A 3UV7A 2EH4A 4H4EA 2PB6A 3KWPA 2NPNA 2PCMA 3HH1A 1PJSA 2E4RA 2PCHA 2OWVA 2CBFA 2DSHA 2DV4A 2DSIA 2ELEA 2P5CA 2QBUA 2OWGA 3NDCA 3ND1A 2PCIA 4MV5A 2EL2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HUV A;  2DV3 A;  2OWU A;  2EH2 A;  2EN5 A;  2EK7 A;  2EK4 A;  2EL1 A;  2E17 A;  2DV7 A;  2P6K A;  2E8S A;  1S4D A;  2Z6R A;  2EMU A;  2HUX A;  2P5F A;  2OWF A;  2DV5 A;  2EKA A;  2EL0 A;  2P6I A;  2YBQ A;  2E0K A;  2E15 A;  2ZVB A;  2DXV A;  2P2X A;  2E16 A;  2EJK A;  2PB5 A;  3I4T A;  2EK2 A;  1VHV A;  2E0N A;  4E16 A;  2P9D A;  1PJT A;  2HUQ A;  2OWK A;  2PB4 A;  2EGB A;  2DSG A;  2PCK A;  2BB3 A;  5HW4 A;  1WYZ A;  2E8H A;  2DXW A;  2EL3 A;  2P6D A;  2PCG A;  2EGS A;  2E8Q A;  1VE2 A;  2E4N A;  2DEK A;  2EK3 A;  1PJQ A;  2DXX A;  3NUT A;  2ENI A;  2ED5 A;  1VA0 A;  2EEQ A;  2EJZ A;  3FFY A;  1V9A A;  2EGL A;  2EHC A;  1WDE A;  1WNG A;  2EMR A;  2EJJ A;  2ELD A;  2YBO A;  2HUT A;  2E07 A;  2PCA A;  2EH5 A;  1CBF A;  2E8R A;  2E7R A;  2EHL A;  2HR8 A;  2P6L A;  1VCE A;  2ZVC A;  3NEI A;  2ED3 A;  2E08 A;  3FQ6 A;  2EH4 A;  2PB6 A;  3KWP A;  2NPN A;  2PCM A;  3HH1 A;  1PJS A;  2E4R A;  2PCH A;  2OWV A;  2CBF A;  2DSH A;  2DV4 A;  2DSI A;  2ELE A;  2P5C A;  2QBU A;  2OWG A;  3NDC A;  3ND1 A;  2PCI A;  2EL2 A; 
#chains in the Genus database with same CATH topology
 2HUV A;  3UV6 A;  2DV3 A;  3DNF A;  2OWU A;  2EH2 A;  2EN5 A;  2EK7 A;  3ZGN A;  3KE8 A;  2EK4 A;  2EL1 A;  2E17 A;  2DV7 A;  2P6K A;  3SZO A;  2E8S A;  3UWM A;  1S4D A;  3UV3 A;  3KEF A;  2Z6R A;  3TIX B;  2EMU A;  2HUX A;  2P5F A;  4MV0 A;  2OWF A;  2DV5 A;  2EKA A;  2EL0 A;  2P6I A;  2YBQ A;  2E0K A;  2E15 A;  2ZVB A;  2DXV A;  2P2X A;  2E16 A;  2EJK A;  2PB5 A;  4H4D A;  3I4T A;  2EK2 A;  1VHV A;  2E0N A;  4E16 A;  2P9D A;  1PJT A;  2HUQ A;  4N7B A;  3URK A;  3SZL A;  2OWK A;  2PB4 A;  2EGB A;  2DSG A;  2PCK A;  3KEL A;  2BB3 A;  5HW4 A;  3KE9 A;  1WYZ A;  2E8H A;  2DXW A;  2EL3 A;  2P6D A;  2PCG A;  3KEM A;  3T0G A;  2EGS A;  3LMM A;  3UTD A;  2E8Q A;  1VE2 A;  2E4N A;  2KYY A;  2DEK A;  2EK3 A;  1PJQ A;  2DXX A;  3NUT A;  2ENI A;  2ED5 A;  1VA0 A;  4MUY A;  2EEQ A;  2EJZ A;  3FFY A;  1V9A A;  2EGL A;  2EHC A;  1WDE A;  1WNG A;  2EMR A;  3T0F A;  3SZU A;  2EJJ A;  2ELD A;  2YBO A;  3F7T A;  2HUT A;  2E07 A;  2PCA A;  2EH5 A;  1CBF A;  2E8R A;  2E7R A;  2EHL A;  2HR8 A;  2P6L A;  3UTC A;  1VCE A;  4H4C A;  3ZGL A;  2ZVC A;  4MUX A;  4EB3 A;  3NEI A;  2ED3 A;  2E08 A;  3FQ6 A;  3UV7 A;  2EH4 A;  4H4E A;  2PB6 A;  3KWP A;  2NPN A;  2PCM A;  3HH1 A;  1PJS A;  2E4R A;  2PCH A;  2OWV A;  2CBF A;  2DSH A;  2DV4 A;  2DSI A;  2ELE A;  2P5C A;  2QBU A;  2OWG A;  3NDC A;  3ND1 A;  2PCI A;  4MV5 A;  2EL2 A; 
#chains in the Genus database with same CATH homology
 2HUV A;  3UV6 A;  2DV3 A;  3DNF A;  2OWU A;  2EH2 A;  2EN5 A;  2EK7 A;  3ZGN A;  3KE8 A;  2EK4 A;  2EL1 A;  2E17 A;  2DV7 A;  2P6K A;  3SZO A;  2E8S A;  3UWM A;  1S4D A;  3UV3 A;  3KEF A;  2Z6R A;  3TIX B;  2EMU A;  2HUX A;  2P5F A;  4MV0 A;  2OWF A;  2DV5 A;  2EKA A;  2EL0 A;  2P6I A;  2YBQ A;  2E0K A;  2E15 A;  2ZVB A;  2DXV A;  2P2X A;  2E16 A;  2EJK A;  2PB5 A;  4H4D A;  3I4T A;  2EK2 A;  1VHV A;  2E0N A;  4E16 A;  2P9D A;  1PJT A;  2HUQ A;  4N7B A;  3URK A;  3SZL A;  2OWK A;  2PB4 A;  2EGB A;  2DSG A;  2PCK A;  3KEL A;  2BB3 A;  5HW4 A;  3KE9 A;  1WYZ A;  2E8H A;  2DXW A;  2EL3 A;  2P6D A;  2PCG A;  3KEM A;  3T0G A;  2EGS A;  3LMM A;  3UTD A;  2E8Q A;  1VE2 A;  2E4N A;  2KYY A;  2DEK A;  2EK3 A;  1PJQ A;  2DXX A;  3NUT A;  2ENI A;  2ED5 A;  1VA0 A;  4MUY A;  2EEQ A;  2EJZ A;  3FFY A;  1V9A A;  2EGL A;  2EHC A;  1WDE A;  1WNG A;  2EMR A;  3T0F A;  3SZU A;  2EJJ A;  2ELD A;  2YBO A;  3F7T A;  2HUT A;  2E07 A;  2PCA A;  2EH5 A;  1CBF A;  2E8R A;  2E7R A;  2EHL A;  2HR8 A;  2P6L A;  3UTC A;  1VCE A;  4H4C A;  3ZGL A;  2ZVC A;  4MUX A;  4EB3 A;  3NEI A;  2ED3 A;  2E08 A;  3FQ6 A;  3UV7 A;  2EH4 A;  4H4E A;  2PB6 A;  3KWP A;  2NPN A;  2PCM A;  3HH1 A;  1PJS A;  2E4R A;  2PCH A;  2OWV A;  2CBF A;  2DSH A;  2DV4 A;  2DSI A;  2ELE A;  2P5C A;  2QBU A;  2OWG A;  3NDC A;  3ND1 A;  2PCI A;  4MV5 A;  2EL2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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