2E16A

Crystal structure of glu140 to arg mutant of diphthine synthase
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPRGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords Probable diphthine synthase
total genus 82
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-10-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2e16A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2e16A01
4E16A 2PCMA 3NUTA 1WDEA 2E08A 2E8HA 2EGLA 2P9DA 2EHLA 2OWKA 2EH5A 2DV7A 2EL0A 2PCKA 2PB6A 2EGBA 1CBFA 2EEQA 1PJQA 2E07A 1WYZA 2P6IA 2DSGA 2ZVCA 2YBOA 2EHCA 1VA0A 2ED3A 2EL2A 3KWPA 2DV3A 2ED5A 2DXVA 3FQ6A 2DXWA 2HUQA 2PB5A 2ZVBA 2E16A 2P2XA 2PB4A 2E8SA 1PJTA 2EN5A 2Z6RA 5HW4A 2BB3A 2EGSA 2EMUA 2HR8A 2HUXA 2EK7A 3HH1A 2EMRA 2EL1A 2CBFA 2PCHA 2E0KA 2EK3A 2E4NA 2HUVA 2DEKA 2ENIA 2OWUA 2EK4A 2DV5A 2EH4A 2EK2A 2E7RA 2P6DA 1V9AA 2E4RA 2E17A 1VCEA 2P5CA 2EH2A 2E0NA 2E8RA 2P6LA 2DSHA 3NEIA 2EJZA 2DXXA 2EKAA 1PJSA 2P5FA 2DSIA 2E15A 3I4TA 3FFYA 2HUTA 2OWGA 2EJJA 2QBUA 2EJKA 2OWFA 2PCGA 2P6KA 2NPNA 1WNGA 2YBQA 3ND1A 2ELDA 1VHVA 1S4DA 2PCIA 3NDCA 2E8QA 2DV4A 2PCAA 2OWVA 2EL3A 2ELEA 1VE2A
chains in the Genus database with same CATH superfamily
4EB3A 3UWMA 4E16A 2PCMA 3SZLA 3NUTA 1WDEA 4MV0A 2E08A 2E8HA 2EGLA 2P9DA 4N7BA 2EHLA 2OWKA 2EH5A 2DV7A 2EL0A 2PCKA 2PB6A 2EGBA 1CBFA 2EEQA 4H4EA 1PJQA 2E07A 1WYZA 3KEFA 2P6IA 2DSGA 2ZVCA 3KE9A 2YBOA 4MV5A 2EHCA 1VA0A 2ED3A 2EL2A 3KWPA 2DV3A 2ED5A 2DXVA 3FQ6A 2DXWA 2HUQA 2PB5A 2ZVBA 2E16A 3UV7A 2P2XA 3ZGNA 2PB4A 2E8SA 1PJTA 2EN5A 2Z6RA 5HW4A 2BB3A 2EGSA 3SZUA 2EMUA 2HR8A 2HUXA 2EK7A 3HH1A 3KEMA 4H4CA 2EMRA 2EL1A 2CBFA 2PCHA 2E0KA 2EK3A 2E4NA 2HUVA 3T0FA 2DEKA 2ENIA 3UTDA 2OWUA 2EK4A 2DV5A 2EH4A 2EK2A 3TIXB 2E7RA 2P6DA 3UV6A 1V9AA 3KELA 2E4RA 3UV3A 2E17A 1VCEA 2P5CA 2EH2A 4H4DA 2E0NA 2E8RA 2P6LA 2DSHA 3NEIA 4MUYA 2EJZA 2DXXA 2EKAA 1PJSA 2P5FA 2DSIA 2E15A 3I4TA 3FFYA 2HUTA 3KE8A 3ZGLA 3DNFA 3UTCA 2OWGA 2EJJA 2QBUA 2EJKA 2OWFA 2PCGA 3T0GA 2P6KA 2NPNA 3URKA 1WNGA 2YBQA 3ND1A 2ELDA 1VHVA 1S4DA 2KYYA 2PCIA 3NDCA 2E8QA 2DV4A 2PCAA 2OWVA 3SZOA 4MUXA 2EL3A 3F7TA 3LMMA 2ELEA 1VE2A
chains in the Genus database with same CATH topology
4EB3A 3UWMA 4E16A 2PCMA 3SZLA 3NUTA 1WDEA 4MV0A 2E08A 2E8HA 2EGLA 2P9DA 4N7BA 2EHLA 2OWKA 2EH5A 2DV7A 2EL0A 2PCKA 2PB6A 2EGBA 1CBFA 2EEQA 4H4EA 1PJQA 2E07A 1WYZA 3KEFA 2P6IA 2DSGA 2ZVCA 3KE9A 2YBOA 4MV5A 2EHCA 1VA0A 2ED3A 2EL2A 3KWPA 2DV3A 2ED5A 2DXVA 3FQ6A 2DXWA 2HUQA 2PB5A 2ZVBA 2E16A 3UV7A 2P2XA 3ZGNA 2PB4A 2E8SA 1PJTA 2EN5A 2Z6RA 5HW4A 2BB3A 2EGSA 3SZUA 2EMUA 2HR8A 2HUXA 2EK7A 3HH1A 3KEMA 4H4CA 2EMRA 2EL1A 2CBFA 2PCHA 2E0KA 2EK3A 2E4NA 2HUVA 3T0FA 2DEKA 2ENIA 3UTDA 2OWUA 2EK4A 2DV5A 2EH4A 2EK2A 3TIXB 2E7RA 2P6DA 3UV6A 1V9AA 3KELA 2E4RA 3UV3A 2E17A 1VCEA 2P5CA 2EH2A 4H4DA 2E0NA 2E8RA 2P6LA 2DSHA 3NEIA 4MUYA 2EJZA 2DXXA 2EKAA 1PJSA 2P5FA 2DSIA 2E15A 3I4TA 3FFYA 2HUTA 3KE8A 3ZGLA 3DNFA 3UTCA 2OWGA 2EJJA 2QBUA 2EJKA 2OWFA 2PCGA 3T0GA 2P6KA 2NPNA 3URKA 1WNGA 2YBQA 3ND1A 2ELDA 1VHVA 1S4DA 2KYYA 2PCIA 3NDCA 2E8QA 2DV4A 2PCAA 2OWVA 3SZOA 4MUXA 2EL3A 3F7TA 3LMMA 2ELEA 1VE2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E16 A;  2PCM A;  3NUT A;  1WDE A;  2E08 A;  2E8H A;  2EGL A;  2P9D A;  2EHL A;  2OWK A;  2EH5 A;  2DV7 A;  2EL0 A;  2PCK A;  2PB6 A;  2EGB A;  1CBF A;  2EEQ A;  1PJQ A;  2E07 A;  1WYZ A;  2P6I A;  2DSG A;  2ZVC A;  2YBO A;  2EHC A;  1VA0 A;  2ED3 A;  2EL2 A;  3KWP A;  2DV3 A;  2ED5 A;  2DXV A;  3FQ6 A;  2DXW A;  2HUQ A;  2PB5 A;  2ZVB A;  2E16 A;  2P2X A;  2PB4 A;  2E8S A;  1PJT A;  2EN5 A;  2Z6R A;  5HW4 A;  2BB3 A;  2EGS A;  2EMU A;  2HR8 A;  2HUX A;  2EK7 A;  3HH1 A;  2EMR A;  2EL1 A;  2CBF A;  2PCH A;  2E0K A;  2EK3 A;  2E4N A;  2HUV A;  2DEK A;  2ENI A;  2OWU A;  2EK4 A;  2DV5 A;  2EH4 A;  2EK2 A;  2E7R A;  2P6D A;  1V9A A;  2E4R A;  2E17 A;  1VCE A;  2P5C A;  2EH2 A;  2E0N A;  2E8R A;  2P6L A;  2DSH A;  3NEI A;  2EJZ A;  2DXX A;  2EKA A;  1PJS A;  2P5F A;  2DSI A;  2E15 A;  3I4T A;  3FFY A;  2HUT A;  2OWG A;  2EJJ A;  2QBU A;  2EJK A;  2OWF A;  2PCG A;  2P6K A;  2NPN A;  1WNG A;  2YBQ A;  3ND1 A;  2ELD A;  1VHV A;  1S4D A;  2PCI A;  3NDC A;  2E8Q A;  2DV4 A;  2PCA A;  2OWV A;  2EL3 A;  2ELE A;  1VE2 A; 
#chains in the Genus database with same CATH topology
 4EB3 A;  3UWM A;  4E16 A;  2PCM A;  3SZL A;  3NUT A;  1WDE A;  4MV0 A;  2E08 A;  2E8H A;  2EGL A;  2P9D A;  4N7B A;  2EHL A;  2OWK A;  2EH5 A;  2DV7 A;  2EL0 A;  2PCK A;  2PB6 A;  2EGB A;  1CBF A;  2EEQ A;  4H4E A;  1PJQ A;  2E07 A;  1WYZ A;  3KEF A;  2P6I A;  2DSG A;  2ZVC A;  3KE9 A;  2YBO A;  4MV5 A;  2EHC A;  1VA0 A;  2ED3 A;  2EL2 A;  3KWP A;  2DV3 A;  2ED5 A;  2DXV A;  3FQ6 A;  2DXW A;  2HUQ A;  2PB5 A;  2ZVB A;  2E16 A;  3UV7 A;  2P2X A;  3ZGN A;  2PB4 A;  2E8S A;  1PJT A;  2EN5 A;  2Z6R A;  5HW4 A;  2BB3 A;  2EGS A;  3SZU A;  2EMU A;  2HR8 A;  2HUX A;  2EK7 A;  3HH1 A;  3KEM A;  4H4C A;  2EMR A;  2EL1 A;  2CBF A;  2PCH A;  2E0K A;  2EK3 A;  2E4N A;  2HUV A;  3T0F A;  2DEK A;  2ENI A;  3UTD A;  2OWU A;  2EK4 A;  2DV5 A;  2EH4 A;  2EK2 A;  3TIX B;  2E7R A;  2P6D A;  3UV6 A;  1V9A A;  3KEL A;  2E4R A;  3UV3 A;  2E17 A;  1VCE A;  2P5C A;  2EH2 A;  4H4D A;  2E0N A;  2E8R A;  2P6L A;  2DSH A;  3NEI A;  4MUY A;  2EJZ A;  2DXX A;  2EKA A;  1PJS A;  2P5F A;  2DSI A;  2E15 A;  3I4T A;  3FFY A;  2HUT A;  3KE8 A;  3ZGL A;  3DNF A;  3UTC A;  2OWG A;  2EJJ A;  2QBU A;  2EJK A;  2OWF A;  2PCG A;  3T0G A;  2P6K A;  2NPN A;  3URK A;  1WNG A;  2YBQ A;  3ND1 A;  2ELD A;  1VHV A;  1S4D A;  2KYY A;  2PCI A;  3NDC A;  2E8Q A;  2DV4 A;  2PCA A;  2OWV A;  3SZO A;  4MUX A;  2EL3 A;  3F7T A;  3LMM A;  2ELE A;  1VE2 A; 
#chains in the Genus database with same CATH homology
 4EB3 A;  3UWM A;  4E16 A;  2PCM A;  3SZL A;  3NUT A;  1WDE A;  4MV0 A;  2E08 A;  2E8H A;  2EGL A;  2P9D A;  4N7B A;  2EHL A;  2OWK A;  2EH5 A;  2DV7 A;  2EL0 A;  2PCK A;  2PB6 A;  2EGB A;  1CBF A;  2EEQ A;  4H4E A;  1PJQ A;  2E07 A;  1WYZ A;  3KEF A;  2P6I A;  2DSG A;  2ZVC A;  3KE9 A;  2YBO A;  4MV5 A;  2EHC A;  1VA0 A;  2ED3 A;  2EL2 A;  3KWP A;  2DV3 A;  2ED5 A;  2DXV A;  3FQ6 A;  2DXW A;  2HUQ A;  2PB5 A;  2ZVB A;  2E16 A;  3UV7 A;  2P2X A;  3ZGN A;  2PB4 A;  2E8S A;  1PJT A;  2EN5 A;  2Z6R A;  5HW4 A;  2BB3 A;  2EGS A;  3SZU A;  2EMU A;  2HR8 A;  2HUX A;  2EK7 A;  3HH1 A;  3KEM A;  4H4C A;  2EMR A;  2EL1 A;  2CBF A;  2PCH A;  2E0K A;  2EK3 A;  2E4N A;  2HUV A;  3T0F A;  2DEK A;  2ENI A;  3UTD A;  2OWU A;  2EK4 A;  2DV5 A;  2EH4 A;  2EK2 A;  3TIX B;  2E7R A;  2P6D A;  3UV6 A;  1V9A A;  3KEL A;  2E4R A;  3UV3 A;  2E17 A;  1VCE A;  2P5C A;  2EH2 A;  4H4D A;  2E0N A;  2E8R A;  2P6L A;  2DSH A;  3NEI A;  4MUY A;  2EJZ A;  2DXX A;  2EKA A;  1PJS A;  2P5F A;  2DSI A;  2E15 A;  3I4T A;  3FFY A;  2HUT A;  3KE8 A;  3ZGL A;  3DNF A;  3UTC A;  2OWG A;  2EJJ A;  2QBU A;  2EJK A;  2OWF A;  2PCG A;  3T0G A;  2P6K A;  2NPN A;  3URK A;  1WNG A;  2YBQ A;  3ND1 A;  2ELD A;  1VHV A;  1S4D A;  2KYY A;  2PCI A;  3NDC A;  2E8Q A;  2DV4 A;  2PCA A;  2OWV A;  3SZO A;  4MUX A;  2EL3 A;  3F7T A;  3LMM A;  2ELE A;  1VE2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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