2E2HL

Rna polymerase ii elongation complex at 5 mm mg2+ with gtp
Total Genus 2
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule keywords 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'
molecule tags Transcription,transferase/dna-rna hybrid
total genus 2
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2006-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2e2hL00
1TWHL 3S1NL 3HOVL 3GTML 4BY1L 4BY7L 4A3EL 4A3LL 5C44L 5IP9L 3GTOL 4A3IL 3S2DL 4QIWP 1TWFL 3K7AL 1TWAL 5M5XL 1I50L 5M3ML 4A3KL 4A93L 4A3GL 3I4ML 3RZOL 3S16L 2E2HL 4A3FL 5M5WL 2JA5L 1SFOL 3CQZL 3HOUL 3GTQL 1TWCL 2B63L 3PO2L 2R92L 3S2HL 2R7ZL 4C3JL 3HOWL 2JA8L 5FLML 5IYBL 4C3IL 4C2M1 2WAQP 3GTJL 3I4NL 2YU9L 5IYCL 2NVYL 3H0GL 4C3HL 3S15L 4AYBP 4A3ML 3S14L 2R93L 1Y1VL 3M3YL 3H3VM 5M5YL 4Y7NL 4BBRL 1Y1WL 3S1ML 5C4XL 1K83L 3HOXL 1I6HL 1I3QL 3S1RL 2JA7L 3HOYL 1WCML 4BBSL 5C3EL 2NVXL 2WB1P 2Y0SP 3HKZP 2VUML 3GTPL 2PMZP 3RZDL 3M4OL 2JA6L 3FKIL 4A3CL 4A3JL 2NVTL 3GTGL 4A3DL 2E2IL 4Y52L 4X6AL 1R9TL 3GTLL 4A3BL 4BXXL 1TWGL 3GTKL 3S17L 3HOZL 3S1QL 5M3FL 2E2JL 2NVQL 3PO3L 5FJ8L 5C4JL 5IYDL 5IP7L
chains in the Genus database with same CATH superfamily
1NXGA 2AQCA 4BY1L 3QQCE 1VZGA 4A3EL 5IP9L 5GAHc 3LNLA 2ERJA 3LWOB 1RYTA 4A3IL 5MFPA 4QIWP 1T9PA 3LWPB 4YWLA 4A3GL 3I4ML 4WFN1 3B08B 4TPUA 6RXNA 2VL6A 1IRNA 3HJYB 1DVBA 4AHYA 2XJSA 4A3FL 3CQZL 3GTQL 1TWCL 1NXEA 5GADc 3S2HL 2R92L 3B0AB 2JA8L 2WAQP 3GTJL 3LWVB 5EINC 4ZN1B 1Y1VL 2Z3RB 4Y7NL 4AR5A 2RDVA 3PKJA 2DSXA 1K83L 3HOXL 1B2JA 3KYYA 2M6PA 3S1RL 2CKAA 2JA7L 1T9OA 2BE5D 4POFA 2NVXL 2Y0SP 3HKZP 4V196 2JI2A 2XJVA 1CADA 3HJWB 2PMZP 1IW7D 3LWQB 1H7VA 4A3JL 3PIP1 1FHHA 1R0GA 3P8BA 2V3BB 3J7Z1 4ZN3B 3GTKL 3S17L 2Z3QB 1T9QA 2MS3A 1SMWA 2PVXA 1R0FA 3PZAA 4RXNA 2ERSA 2J9UB 3HOVL 2O5JD 1PFWA 4K9FA 3KYVA 1YK4A 4UY81 3SS2A 5C44L 1LKOA 3VPBE 3GTOL 4AHZA 5IY0A 3K35A 3K7AL 5M5XL 1I50L 1CAAA 4JAEA 5M3ML 2XJUA 5AN9H 4JAFA 3IU3I 1YK5A 1VZHA 2JA5L 1SFOL 4AR4A 1RYQA 1OWBA 2B63L 3PO2L 1NNQA 2V0FA 1BQ8A 1LKPA 2JI1A 1ODHA 3H97A 4C3JL 3HOWL 5FLML 2A6ED 5JVH1 5EIOC 4C2M1 4B8CD 1E8JA 4JADA 4AI1A 5IYCL 3QVDA 4U671 3H9CA 2JI3A 3KYUA 2A6HD 1VCXA 5M5YL 1FHMA 1Y1WL 3S1ML 1BRFA 3RYGA 3A44A 4E6YA 4BBSL 1F4LA 5K2ME 3WWLA 1ZRPA 4GS7D 1S24A 3NFPI 1IU6A 4A3CL 1BE7A 3GTGL 1PFVA 2CKCA 2NYDA 1PZXA 4X6AL 1LKMA 1B13A 3GTLL 1C09A 3S1QL 5DM71 1OWCA 1RWDA 2KKDA 5IYDL 4BY7L 3H99A 2C6BA 3LWRB 1YV1A 2PPTA 4AI0A 2HVYC 3S2DL 1TWFL 2L0ZA 1BFYA 1WJVA 2C6AA 4A93L 3RZOL 2HR5A 5MFZA 3LPEB 5GAEc 3PL5A 5MGNA 2PSMC 1SMUA 1BQ9A 5IYBL 7RXNA 4C3IL 1RDVA 3I4NL 3KYXA 1LTLA 2LCQA 2NVYL 1QQTA 3S15L 4LHLA 3M3YL 3H3VM 2A68D 4BBRL 1S30A 3ZG6A 2AYJA 3H9BA 5RXNA 1IU5A 1WCML 1YUZA 2APOB 2A69D 2XJPA 5C3EL 2H12A 3FDJA 3HAXC 4YWMA 5AI3A 4AHWA 2VUML 3GTPL 3RZ6A 3RZDL 1VZIA 2JA6L 3P2AA 4TVMA 2PVEA 5JVG1 2QL0A 2NVTL 8RXNA 4XXBB 3MSUA 2E2IL 3PKIA 3PIO1 1R9TL 2PYAA 2XJRA 2M4VA 2B5ID 3HOZL 4AR3A 1IROA 3WWNB 2E2JL 2NVQL 3PO3L 3MPSA 2GMGA 4AHXA 1TWHL 3S1NL 3GTML 3PWFA 4POGA 4AR6A 2ZIXA 1Z92B 1SMMA 1TWAL 4A3KL 1B71A 1RB9A 1QCVA 3S16L 1QYBA 2E2HL 1R0JA 5M5WL 4AI3A 3HOUL 2EY4E 1JYBA 2R7ZL 5GAGc 3RZTA 2M4YA 1R0HA 2YU9L 1PFYA 3H0GL 4C3HL 4AYBP 4A3ML 3S14L 2R93L 1S2ZA 4AI2A 2XJQA 2KN9A 3KYWA 1B2OA 4XGHA 2AUSB 2RFKB 5AI2A 5H1Sc 5C4XL 1I6HL 1RDGA 2M6OA 3JR7A 1I3QL 3HOYL 3MQKB 5MF6A 1R0IA 1YUXA 4G6BA 2V0EA 4JAGA 2WB1P 2XJTA 4LHNA 3M4OL 1DX8A 3FKIL 1P7PA 5DM61 1PFUA 4A3DL 4Y52L 3J7Y1 4A3BL 4BXXL 1TWGL 5MLC3 4ME3A 5M3FL 2K2DA 5FJ8L 5C4JL 2CR8A 4A3LL 5IP7L
chains in the Genus database with same CATH topology
1TWHL 3S1NL 3HOVL 3GTML 4BY1L 4BY7L 4A3EL 4A3LL 5C44L 5IP9L 3GTOL 4A3IL 3S2DL 4QIWP 1TWFL 3K7AL 1TWAL 5M5XL 1I50L 5M3ML 4A3KL 4A93L 4A3GL 3I4ML 3RZOL 3S16L 2E2HL 4A3FL 5M5WL 2JA5L 1SFOL 3CQZL 3HOUL 3GTQL 1TWCL 2B63L 3PO2L 2R92L 3S2HL 2R7ZL 4C3JL 3HOWL 2JA8L 5FLML 5IYBL 4C3IL 4C2M1 2WAQP 3GTJL 3I4NL 2YU9L 5IYCL 2NVYL 3H0GL 4C3HL 3S15L 4AYBP 4A3ML 3S14L 2R93L 1Y1VL 3M3YL 3H3VM 5M5YL 4Y7NL 4BBRL 1Y1WL 3S1ML 5C4XL 1K83L 3HOXL 1I6HL 1I3QL 3S1RL 2JA7L 3HOYL 1WCML 4BBSL 5C3EL 2NVXL 2WB1P 2Y0SP 3HKZP 2VUML 3GTPL 2PMZP 3RZDL 3M4OL 2JA6L 3FKIL 4A3CL 4A3JL 2NVTL 3GTGL 4A3DL 2E2IL 4Y52L 4X6AL 1R9TL 3GTLL 4A3BL 4BXXL 1TWGL 3GTKL 3S17L 3HOZL 3S1QL 5M3FL 2E2JL 2NVQL 3PO3L 5FJ8L 5C4JL 5IYDL 5IP7L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TWH L;  3S1N L;  3HOV L;  3GTM L;  4BY1 L;  4BY7 L;  4A3E L;  4A3L L;  5C44 L;  5IP9 L;  3GTO L;  4A3I L;  3S2D L;  4QIW P;  1TWF L;  3K7A L;  1TWA L;  5M5X L;  1I50 L;  5M3M L;  4A3K L;  4A93 L;  4A3G L;  3I4M L;  3RZO L;  3S16 L;  2E2H L;  4A3F L;  5M5W L;  2JA5 L;  1SFO L;  3CQZ L;  3HOU L;  3GTQ L;  1TWC L;  2B63 L;  3PO2 L;  2R92 L;  3S2H L;  2R7Z L;  4C3J L;  3HOW L;  2JA8 L;  5FLM L;  5IYB L;  4C3I L;  4C2M 1;  2WAQ P;  3GTJ L;  3I4N L;  2YU9 L;  5IYC L;  2NVY L;  3H0G L;  4C3H L;  3S15 L;  4AYB P;  4A3M L;  3S14 L;  2R93 L;  1Y1V L;  3M3Y L;  3H3V M;  5M5Y L;  4Y7N L;  4BBR L;  1Y1W L;  3S1M L;  5C4X L;  1K83 L;  3HOX L;  1I6H L;  1I3Q L;  3S1R L;  2JA7 L;  3HOY L;  1WCM L;  4BBS L;  5C3E L;  2NVX L;  2WB1 P;  2Y0S P;  3HKZ P;  2VUM L;  3GTP L;  2PMZ P;  3RZD L;  3M4O L;  2JA6 L;  3FKI L;  4A3C L;  4A3J L;  2NVT L;  3GTG L;  4A3D L;  2E2I L;  4Y52 L;  4X6A L;  1R9T L;  3GTL L;  4A3B L;  4BXX L;  1TWG L;  3GTK L;  3S17 L;  3HOZ L;  3S1Q L;  5M3F L;  2E2J L;  2NVQ L;  3PO3 L;  5FJ8 L;  5C4J L;  5IYD L;  5IP7 L; 
#chains in the Genus database with same CATH topology
 1NXG A;  2AQC A;  4BY1 L;  3QQC E;  1VZG A;  4A3E L;  5IP9 L;  5GAH c;  3LNL A;  2ERJ A;  3LWO B;  1RYT A;  4A3I L;  5MFP A;  4QIW P;  1T9P A;  3LWP B;  4YWL A;  4A3G L;  3I4M L;  4WFN 1;  3B08 B;  4TPU A;  6RXN A;  2VL6 A;  1IRN A;  3HJY B;  1DVB A;  4AHY A;  2XJS A;  4A3F L;  3CQZ L;  3GTQ L;  1TWC L;  1NXE A;  5GAD c;  3S2H L;  2R92 L;  3B0A B;  2JA8 L;  2WAQ P;  3GTJ L;  3LWV B;  5EIN C;  4ZN1 B;  1Y1V L;  2Z3R B;  4Y7N L;  4AR5 A;  2RDV A;  3PKJ A;  2DSX A;  1K83 L;  3HOX L;  1B2J A;  3KYY A;  2M6P A;  3S1R L;  2CKA A;  2JA7 L;  1T9O A;  2BE5 D;  4POF A;  2NVX L;  2Y0S P;  3HKZ P;  4V19 6;  2JI2 A;  2XJV A;  1CAD A;  3HJW B;  2PMZ P;  1IW7 D;  3LWQ B;  1H7V A;  4A3J L;  3PIP 1;  1FHH A;  1R0G A;  3P8B A;  2V3B B;  3J7Z 1;  4ZN3 B;  3GTK L;  3S17 L;  2Z3Q B;  1T9Q A;  2MS3 A;  1SMW A;  2PVX A;  1R0F A;  3PZA A;  4RXN A;  2ERS A;  2J9U B;  3HOV L;  2O5J D;  1PFW A;  4K9F A;  3KYV A;  1YK4 A;  4UY8 1;  3SS2 A;  5C44 L;  1LKO A;  3VPB E;  3GTO L;  4AHZ A;  5IY0 A;  3K35 A;  3K7A L;  5M5X L;  1I50 L;  1CAA A;  4JAE A;  5M3M L;  2XJU A;  5AN9 H;  4JAF A;  3IU3 I;  1YK5 A;  1VZH A;  2JA5 L;  1SFO L;  4AR4 A;  1RYQ A;  1OWB A;  2B63 L;  3PO2 L;  1NNQ A;  2V0F A;  1BQ8 A;  1LKP A;  2JI1 A;  1ODH A;  3H97 A;  4C3J L;  3HOW L;  5FLM L;  2A6E D;  5JVH 1;  5EIO C;  4C2M 1;  4B8C D;  1E8J A;  4JAD A;  4AI1 A;  5IYC L;  3QVD A;  4U67 1;  3H9C A;  2JI3 A;  3KYU A;  2A6H D;  1VCX A;  5M5Y L;  1FHM A;  1Y1W L;  3S1M L;  1BRF A;  3RYG A;  3A44 A;  4E6Y A;  4BBS L;  1F4L A;  5K2M E;  3WWL A;  1ZRP A;  4GS7 D;  1S24 A;  3NFP I;  1IU6 A;  4A3C L;  1BE7 A;  3GTG L;  1PFV A;  2CKC A;  2NYD A;  1PZX A;  4X6A L;  1LKM A;  1B13 A;  3GTL L;  1C09 A;  3S1Q L;  5DM7 1;  1OWC A;  1RWD A;  2KKD A;  5IYD L;  4BY7 L;  3H99 A;  2C6B A;  3LWR B;  1YV1 A;  2PPT A;  4AI0 A;  2HVY C;  3S2D L;  1TWF L;  2L0Z A;  1BFY A;  1WJV A;  2C6A A;  4A93 L;  3RZO L;  2HR5 A;  5MFZ A;  3LPE B;  5GAE c;  3PL5 A;  5MGN A;  2PSM C;  1SMU A;  1BQ9 A;  5IYB L;  7RXN A;  4C3I L;  1RDV A;  3I4N L;  3KYX A;  1LTL A;  2LCQ A;  2NVY L;  1QQT A;  3S15 L;  4LHL A;  3M3Y L;  3H3V M;  2A68 D;  4BBR L;  1S30 A;  3ZG6 A;  2AYJ A;  3H9B A;  5RXN A;  1IU5 A;  1WCM L;  1YUZ A;  2APO B;  2A69 D;  2XJP A;  5C3E L;  2H12 A;  3FDJ A;  3HAX C;  4YWM A;  5AI3 A;  4AHW A;  2VUM L;  3GTP L;  3RZ6 A;  3RZD L;  1VZI A;  2JA6 L;  3P2A A;  4TVM A;  2PVE A;  5JVG 1;  2QL0 A;  2NVT L;  8RXN A;  4XXB B;  3MSU A;  2E2I L;  3PKI A;  3PIO 1;  1R9T L;  2PYA A;  2XJR A;  2M4V A;  2B5I D;  3HOZ L;  4AR3 A;  1IRO A;  3WWN B;  2E2J L;  2NVQ L;  3PO3 L;  3MPS A;  2GMG A;  4AHX A;  1TWH L;  3S1N L;  3GTM L;  3PWF A;  4POG A;  4AR6 A;  2ZIX A;  1Z92 B;  1SMM A;  1TWA L;  4A3K L;  1B71 A;  1RB9 A;  1QCV A;  3S16 L;  1QYB A;  2E2H L;  1R0J A;  5M5W L;  4AI3 A;  3HOU L;  2EY4 E;  1JYB A;  2R7Z L;  5GAG c;  3RZT A;  2M4Y A;  1R0H A;  2YU9 L;  1PFY A;  3H0G L;  4C3H L;  4AYB P;  4A3M L;  3S14 L;  2R93 L;  1S2Z A;  4AI2 A;  2XJQ A;  2KN9 A;  3KYW A;  1B2O A;  4XGH A;  2AUS B;  2RFK B;  5AI2 A;  5H1S c;  5C4X L;  1I6H L;  1RDG A;  2M6O A;  3JR7 A;  1I3Q L;  3HOY L;  3MQK B;  5MF6 A;  1R0I A;  1YUX A;  4G6B A;  2V0E A;  4JAG A;  2WB1 P;  2XJT A;  4LHN A;  3M4O L;  1DX8 A;  3FKI L;  1P7P A;  5DM6 1;  1PFU A;  4A3D L;  4Y52 L;  3J7Y 1;  4A3B L;  4BXX L;  1TWG L;  5MLC 3;  4ME3 A;  5M3F L;  2K2D A;  5FJ8 L;  5C4J L;  2CR8 A;  4A3L L;  5IP7 L; 
#chains in the Genus database with same CATH homology
 1TWH L;  3S1N L;  3HOV L;  3GTM L;  4BY1 L;  4BY7 L;  4A3E L;  4A3L L;  5C44 L;  5IP9 L;  3GTO L;  4A3I L;  3S2D L;  4QIW P;  1TWF L;  3K7A L;  1TWA L;  5M5X L;  1I50 L;  5M3M L;  4A3K L;  4A93 L;  4A3G L;  3I4M L;  3RZO L;  3S16 L;  2E2H L;  4A3F L;  5M5W L;  2JA5 L;  1SFO L;  3CQZ L;  3HOU L;  3GTQ L;  1TWC L;  2B63 L;  3PO2 L;  2R92 L;  3S2H L;  2R7Z L;  4C3J L;  3HOW L;  2JA8 L;  5FLM L;  5IYB L;  4C3I L;  4C2M 1;  2WAQ P;  3GTJ L;  3I4N L;  2YU9 L;  5IYC L;  2NVY L;  3H0G L;  4C3H L;  3S15 L;  4AYB P;  4A3M L;  3S14 L;  2R93 L;  1Y1V L;  3M3Y L;  3H3V M;  5M5Y L;  4Y7N L;  4BBR L;  1Y1W L;  3S1M L;  5C4X L;  1K83 L;  3HOX L;  1I6H L;  1I3Q L;  3S1R L;  2JA7 L;  3HOY L;  1WCM L;  4BBS L;  5C3E L;  2NVX L;  2WB1 P;  2Y0S P;  3HKZ P;  2VUM L;  3GTP L;  2PMZ P;  3RZD L;  3M4O L;  2JA6 L;  3FKI L;  4A3C L;  4A3J L;  2NVT L;  3GTG L;  4A3D L;  2E2I L;  4Y52 L;  4X6A L;  1R9T L;  3GTL L;  4A3B L;  4BXX L;  1TWG L;  3GTK L;  3S17 L;  3HOZ L;  3S1Q L;  5M3F L;  2E2J L;  2NVQ L;  3PO3 L;  5FJ8 L;  5C4J L;  5IYD L;  5IP7 L; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...