2E2IL

Rna polymerase ii elongation complex in 5 mm mg+2 with 2'-dgtp
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule keywords 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'
molecule tags Transcription,transferase/dna-rna hybrid
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2006-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2e2iL00
2NVTL 4BBSL 3GTPL 3K7AL 5FJ8L 1Y1VL 2YU9L 3GTJL 3HOUL 1SFOL 5C44L 5IP9L 3S1RL 3GTQL 5IP7L 2Y0SP 2B63L 5M5YL 3HOVL 3S1QL 2PMZP 5M3FL 3HKZP 3HOXL 4A3IL 1TWAL 4BXXL 1I50L 5M3ML 2JA6L 4AYBP 1I3QL 4A3CL 2JA8L 4X6AL 3S17L 3S2DL 3GTKL 4A3GL 1TWCL 3S1ML 5C3EL 4A3JL 4A3KL 2NVYL 4A3DL 3S14L 4A3EL 1I6HL 3S15L 4C2M1 3PO2L 2NVXL 4A3BL 4A3ML 2JA7L 3FKIL 3H0GL 4Y52L 3GTOL 1TWHL 5FLML 5M5WL 4BBRL 5IYCL 3S1NL 3H3VM 3M4OL 1TWFL 1Y1WL 3I4NL 4A3LL 3S16L 4QIWP 5M5XL 4C3IL 1R9TL 5C4JL 5C4XL 2NVQL 3GTLL 5IYBL 4C3JL 3RZDL 2R92L 5IYDL 2E2HL 3GTGL 2WAQP 4A93L 3CQZL 3HOYL 4A3FL 3PO3L 3S2HL 2E2IL 2JA5L 3HOZL 1TWGL 3HOWL 3I4ML 4BY1L 1WCML 4C3HL 3M3YL 3GTML 1K83L 4BY7L 2R93L 3RZOL 2R7ZL 2VUML 2E2JL 4Y7NL 2WB1P
chains in the Genus database with same CATH superfamily
3QVDA 3VPBE 3H9BA 2V3BB 3PIP1 5DM61 3S1RL 5IP7L 5RXNA 5M5YL 2EY4E 2PMZP 1Z92B 3HOXL 1PFYA 4ZN1B 1RYTA 5M3ML 1LKMA 3MPSA 3S17L 4POFA 2XJPA 2PSMC 4A3JL 5K2ME 4JADA 1JYBA 1QYBA 1NXEA 2RFKB 3S14L 5GAGc 2CKCA 1B2OA 2A69D 3B08B 3PO2L 2NYDA 3MQKB 3K35A 5EINC 1LKOA 2JA7L 3H99A 2J9UB 5MLC3 3GTOL 4XXBB 3LWVB 1VZIA 2XJRA 4YWLA 1Y1WL 4A3LL 1BE7A 2AYJA 5C4JL 5C4XL 1DVBA 2HR5A 1RYQA 5IYBL 1VZGA 3PL5A 3HJYB 4C3JL 1SMWA 2ERSA 2A6HD 4JAFA 4V196 3HOYL 3PO3L 4GS7D 2JA5L 4ZN3B 3HOWL 2XJSA 3MSUA 2V0EA 1RDVA 1H7VA 1IU5A 1T9PA 4AR6A 1BFYA 4POGA 2PPTA 2LCQA 2H12A 1WJVA 2JI3A 4BBSL 4AI2A 5AI3A 2YU9L 5AI2A 5IP9L 3LWOB 2B63L 1T9QA 1RWDA 4A3IL 1R0GA 2XJUA 2XJTA 1QQTA 1PZXA 2JA6L 3HJWB 2A68D 1I3QL 4A3CL 2L0ZA 2JA8L 3GTKL 4ME3A 2VL6A 4G6BA 3RZ6A 1BQ9A 4AHXA 4C2M1 3LPEB 4AR3A 4A3BL 1BRFA 3WWNB 2O5JD 2RDVA 1PFVA 1OWBA 4E6YA 8RXNA 1TWFL 3I4NL 3S16L 1VCXA 2JI2A 4AI1A 1NNQA 1T9OA 3IU3I 3GTLL 2PVEA 2XJQA 3NFPI 2QL0A 5JVH1 2R92L 1R0JA 5IYDL 1OWCA 2WAQP 3SS2A 1VZHA 4JAEA 2MS3A 3CQZL 5GAHc 3J7Y1 3S2HL 1B2JA 5AN9H 1RB9A 3P2AA 3HOZL 3I4ML 4B8CD 2A6ED 1S24A 1F4LA 1QCVA 2PVXA 5EIOC 3GTML 1K83L 3RZOL 1S2ZA 2DSXA 2ZIXA 4JAGA 2R7ZL 2VUML 2WB1P 1IW7D 2KN9A 3GTPL 3QQCE 3WWLA 3GTJL 3HOUL 5C44L 1YUXA 3J7Z1 4TVMA 3GTQL 5MF6A 4AR4A 2Y0SP 3HOVL 1PFWA 3B0AB 5M3FL 3HKZP 1FHMA 4LHNA 4AHZA 4BXXL 3S2DL 5JVG1 3S1ML 5C3EL 1YUZA 2NVYL 1ODHA 4AR5A 1IRNA 3LWPB 4A3EL 3S15L 1S30A 1R0FA 1BQ8A 4A3ML 2XJVA 3A44A 3RYGA 3FKIL 3LNLA 2BE5D 3H0GL 4UY81 1TWHL 5M5WL 3PKJA 5IYCL 3S1NL 3H3VM 3M4OL 3H97A 4AI3A 2KKDA 4QIWP 4C3IL 3KYWA 2M4VA 3PKIA 1B71A 1NXGA 4RXNA 1CADA 1SMMA 2E2HL 2APOB 2Z3RB 5H1Sc 1PFUA 2C6AA 4BY1L 4C3HL 2B5ID 3JR7A 2R93L 4WFN1 4XGHA 1R0IA 3H9CA 1SMUA 4Y7NL 2GMGA 2NVTL 2JI1A 1R0HA 3RZTA 3K7AL 5FJ8L 1Y1VL 2CKAA 1SFOL 1LKPA 2CR8A 3HAXC 2HVYC 4LHLA 3S1QL 3KYVA 4AHYA 5MFZA 6RXNA 4K9FA 3PZAA 1TWAL 5DM71 1I50L 1RDGA 1YV1A 4U671 4AYBP 5MGNA 4X6AL 2Z3QB 4A3GL 1TWCL 3P8BA 3KYXA 1YK5A 2K2DA 3LWQB 4A3KL 4A3DL 1B13A 2M6PA 5GAEc 2PYAA 2ERJA 1FHHA 5GADc 1C09A 1I6HL 3FDJA 2NVXL 4TPUA 1E8JA 2M4YA 4Y52L 1IROA 3KYUA 5FLML 5MFPA 4BBRL 5IY0A 1ZRPA 2C6BA 1CAAA 5M5XL 2AQCA 1R9TL 1YK4A 2NVQL 1DX8A 3PIO1 2AUSB 3RZDL 3GTGL 3PWFA 3LWRB 4AHWA 4A93L 4YWMA 4A3FL 4AI0A 1LTLA 7RXNA 3KYYA 2E2IL 1TWGL 1WCML 3M3YL 4BY7L 2M6OA 2V0FA 1P7PA 3ZG6A 1IU6A 2E2JL
chains in the Genus database with same CATH topology
2NVTL 4BBSL 3GTPL 3K7AL 5FJ8L 1Y1VL 2YU9L 3GTJL 3HOUL 1SFOL 5C44L 5IP9L 3S1RL 3GTQL 5IP7L 2Y0SP 2B63L 5M5YL 3HOVL 3S1QL 2PMZP 5M3FL 3HKZP 3HOXL 4A3IL 1TWAL 4BXXL 1I50L 5M3ML 2JA6L 4AYBP 1I3QL 4A3CL 2JA8L 4X6AL 3S17L 3S2DL 3GTKL 4A3GL 1TWCL 3S1ML 5C3EL 4A3JL 4A3KL 2NVYL 4A3DL 3S14L 4A3EL 1I6HL 3S15L 4C2M1 3PO2L 2NVXL 4A3BL 4A3ML 2JA7L 3FKIL 3H0GL 4Y52L 3GTOL 1TWHL 5FLML 5M5WL 4BBRL 5IYCL 3S1NL 3H3VM 3M4OL 1TWFL 1Y1WL 3I4NL 4A3LL 3S16L 4QIWP 5M5XL 4C3IL 1R9TL 5C4JL 5C4XL 2NVQL 3GTLL 5IYBL 4C3JL 3RZDL 2R92L 5IYDL 2E2HL 3GTGL 2WAQP 4A93L 3CQZL 3HOYL 4A3FL 3PO3L 3S2HL 2E2IL 2JA5L 3HOZL 1TWGL 3HOWL 3I4ML 4BY1L 1WCML 4C3HL 3M3YL 3GTML 1K83L 4BY7L 2R93L 3RZOL 2R7ZL 2VUML 2E2JL 4Y7NL 2WB1P
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NVT L;  4BBS L;  3GTP L;  3K7A L;  5FJ8 L;  1Y1V L;  2YU9 L;  3GTJ L;  3HOU L;  1SFO L;  5C44 L;  5IP9 L;  3S1R L;  3GTQ L;  5IP7 L;  2Y0S P;  2B63 L;  5M5Y L;  3HOV L;  3S1Q L;  2PMZ P;  5M3F L;  3HKZ P;  3HOX L;  4A3I L;  1TWA L;  4BXX L;  1I50 L;  5M3M L;  2JA6 L;  4AYB P;  1I3Q L;  4A3C L;  2JA8 L;  4X6A L;  3S17 L;  3S2D L;  3GTK L;  4A3G L;  1TWC L;  3S1M L;  5C3E L;  4A3J L;  4A3K L;  2NVY L;  4A3D L;  3S14 L;  4A3E L;  1I6H L;  3S15 L;  4C2M 1;  3PO2 L;  2NVX L;  4A3B L;  4A3M L;  2JA7 L;  3FKI L;  3H0G L;  4Y52 L;  3GTO L;  1TWH L;  5FLM L;  5M5W L;  4BBR L;  5IYC L;  3S1N L;  3H3V M;  3M4O L;  1TWF L;  1Y1W L;  3I4N L;  4A3L L;  3S16 L;  4QIW P;  5M5X L;  4C3I L;  1R9T L;  5C4J L;  5C4X L;  2NVQ L;  3GTL L;  5IYB L;  4C3J L;  3RZD L;  2R92 L;  5IYD L;  2E2H L;  3GTG L;  2WAQ P;  4A93 L;  3CQZ L;  3HOY L;  4A3F L;  3PO3 L;  3S2H L;  2E2I L;  2JA5 L;  3HOZ L;  1TWG L;  3HOW L;  3I4M L;  4BY1 L;  1WCM L;  4C3H L;  3M3Y L;  3GTM L;  1K83 L;  4BY7 L;  2R93 L;  3RZO L;  2R7Z L;  2VUM L;  2E2J L;  4Y7N L;  2WB1 P; 
#chains in the Genus database with same CATH topology
 3QVD A;  3VPB E;  3H9B A;  2V3B B;  3PIP 1;  5DM6 1;  3S1R L;  5IP7 L;  5RXN A;  5M5Y L;  2EY4 E;  2PMZ P;  1Z92 B;  3HOX L;  1PFY A;  4ZN1 B;  1RYT A;  5M3M L;  1LKM A;  3MPS A;  3S17 L;  4POF A;  2XJP A;  2PSM C;  4A3J L;  5K2M E;  4JAD A;  1JYB A;  1QYB A;  1NXE A;  2RFK B;  3S14 L;  5GAG c;  2CKC A;  1B2O A;  2A69 D;  3B08 B;  3PO2 L;  2NYD A;  3MQK B;  3K35 A;  5EIN C;  1LKO A;  2JA7 L;  3H99 A;  2J9U B;  5MLC 3;  3GTO L;  4XXB B;  3LWV B;  1VZI A;  2XJR A;  4YWL A;  1Y1W L;  4A3L L;  1BE7 A;  2AYJ A;  5C4J L;  5C4X L;  1DVB A;  2HR5 A;  1RYQ A;  5IYB L;  1VZG A;  3PL5 A;  3HJY B;  4C3J L;  1SMW A;  2ERS A;  2A6H D;  4JAF A;  4V19 6;  3HOY L;  3PO3 L;  4GS7 D;  2JA5 L;  4ZN3 B;  3HOW L;  2XJS A;  3MSU A;  2V0E A;  1RDV A;  1H7V A;  1IU5 A;  1T9P A;  4AR6 A;  1BFY A;  4POG A;  2PPT A;  2LCQ A;  2H12 A;  1WJV A;  2JI3 A;  4BBS L;  4AI2 A;  5AI3 A;  2YU9 L;  5AI2 A;  5IP9 L;  3LWO B;  2B63 L;  1T9Q A;  1RWD A;  4A3I L;  1R0G A;  2XJU A;  2XJT A;  1QQT A;  1PZX A;  2JA6 L;  3HJW B;  2A68 D;  1I3Q L;  4A3C L;  2L0Z A;  2JA8 L;  3GTK L;  4ME3 A;  2VL6 A;  4G6B A;  3RZ6 A;  1BQ9 A;  4AHX A;  4C2M 1;  3LPE B;  4AR3 A;  4A3B L;  1BRF A;  3WWN B;  2O5J D;  2RDV A;  1PFV A;  1OWB A;  4E6Y A;  8RXN A;  1TWF L;  3I4N L;  3S16 L;  1VCX A;  2JI2 A;  4AI1 A;  1NNQ A;  1T9O A;  3IU3 I;  3GTL L;  2PVE A;  2XJQ A;  3NFP I;  2QL0 A;  5JVH 1;  2R92 L;  1R0J A;  5IYD L;  1OWC A;  2WAQ P;  3SS2 A;  1VZH A;  4JAE A;  2MS3 A;  3CQZ L;  5GAH c;  3J7Y 1;  3S2H L;  1B2J A;  5AN9 H;  1RB9 A;  3P2A A;  3HOZ L;  3I4M L;  4B8C D;  2A6E D;  1S24 A;  1F4L A;  1QCV A;  2PVX A;  5EIO C;  3GTM L;  1K83 L;  3RZO L;  1S2Z A;  2DSX A;  2ZIX A;  4JAG A;  2R7Z L;  2VUM L;  2WB1 P;  1IW7 D;  2KN9 A;  3GTP L;  3QQC E;  3WWL A;  3GTJ L;  3HOU L;  5C44 L;  1YUX A;  3J7Z 1;  4TVM A;  3GTQ L;  5MF6 A;  4AR4 A;  2Y0S P;  3HOV L;  1PFW A;  3B0A B;  5M3F L;  3HKZ P;  1FHM A;  4LHN A;  4AHZ A;  4BXX L;  3S2D L;  5JVG 1;  3S1M L;  5C3E L;  1YUZ A;  2NVY L;  1ODH A;  4AR5 A;  1IRN A;  3LWP B;  4A3E L;  3S15 L;  1S30 A;  1R0F A;  1BQ8 A;  4A3M L;  2XJV A;  3A44 A;  3RYG A;  3FKI L;  3LNL A;  2BE5 D;  3H0G L;  4UY8 1;  1TWH L;  5M5W L;  3PKJ A;  5IYC L;  3S1N L;  3H3V M;  3M4O L;  3H97 A;  4AI3 A;  2KKD A;  4QIW P;  4C3I L;  3KYW A;  2M4V A;  3PKI A;  1B71 A;  1NXG A;  4RXN A;  1CAD A;  1SMM A;  2E2H L;  2APO B;  2Z3R B;  5H1S c;  1PFU A;  2C6A A;  4BY1 L;  4C3H L;  2B5I D;  3JR7 A;  2R93 L;  4WFN 1;  4XGH A;  1R0I A;  3H9C A;  1SMU A;  4Y7N L;  2GMG A;  2NVT L;  2JI1 A;  1R0H A;  3RZT A;  3K7A L;  5FJ8 L;  1Y1V L;  2CKA A;  1SFO L;  1LKP A;  2CR8 A;  3HAX C;  2HVY C;  4LHL A;  3S1Q L;  3KYV A;  4AHY A;  5MFZ A;  6RXN A;  4K9F A;  3PZA A;  1TWA L;  5DM7 1;  1I50 L;  1RDG A;  1YV1 A;  4U67 1;  4AYB P;  5MGN A;  4X6A L;  2Z3Q B;  4A3G L;  1TWC L;  3P8B A;  3KYX A;  1YK5 A;  2K2D A;  3LWQ B;  4A3K L;  4A3D L;  1B13 A;  2M6P A;  5GAE c;  2PYA A;  2ERJ A;  1FHH A;  5GAD c;  1C09 A;  1I6H L;  3FDJ A;  2NVX L;  4TPU A;  1E8J A;  2M4Y A;  4Y52 L;  1IRO A;  3KYU A;  5FLM L;  5MFP A;  4BBR L;  5IY0 A;  1ZRP A;  2C6B A;  1CAA A;  5M5X L;  2AQC A;  1R9T L;  1YK4 A;  2NVQ L;  1DX8 A;  3PIO 1;  2AUS B;  3RZD L;  3GTG L;  3PWF A;  3LWR B;  4AHW A;  4A93 L;  4YWM A;  4A3F L;  4AI0 A;  1LTL A;  7RXN A;  3KYY A;  2E2I L;  1TWG L;  1WCM L;  3M3Y L;  4BY7 L;  2M6O A;  2V0F A;  1P7P A;  3ZG6 A;  1IU6 A;  2E2J L; 
#chains in the Genus database with same CATH homology
 2NVT L;  4BBS L;  3GTP L;  3K7A L;  5FJ8 L;  1Y1V L;  2YU9 L;  3GTJ L;  3HOU L;  1SFO L;  5C44 L;  5IP9 L;  3S1R L;  3GTQ L;  5IP7 L;  2Y0S P;  2B63 L;  5M5Y L;  3HOV L;  3S1Q L;  2PMZ P;  5M3F L;  3HKZ P;  3HOX L;  4A3I L;  1TWA L;  4BXX L;  1I50 L;  5M3M L;  2JA6 L;  4AYB P;  1I3Q L;  4A3C L;  2JA8 L;  4X6A L;  3S17 L;  3S2D L;  3GTK L;  4A3G L;  1TWC L;  3S1M L;  5C3E L;  4A3J L;  4A3K L;  2NVY L;  4A3D L;  3S14 L;  4A3E L;  1I6H L;  3S15 L;  4C2M 1;  3PO2 L;  2NVX L;  4A3B L;  4A3M L;  2JA7 L;  3FKI L;  3H0G L;  4Y52 L;  3GTO L;  1TWH L;  5FLM L;  5M5W L;  4BBR L;  5IYC L;  3S1N L;  3H3V M;  3M4O L;  1TWF L;  1Y1W L;  3I4N L;  4A3L L;  3S16 L;  4QIW P;  5M5X L;  4C3I L;  1R9T L;  5C4J L;  5C4X L;  2NVQ L;  3GTL L;  5IYB L;  4C3J L;  3RZD L;  2R92 L;  5IYD L;  2E2H L;  3GTG L;  2WAQ P;  4A93 L;  3CQZ L;  3HOY L;  4A3F L;  3PO3 L;  3S2H L;  2E2I L;  2JA5 L;  3HOZ L;  1TWG L;  3HOW L;  3I4M L;  4BY1 L;  1WCM L;  4C3H L;  3M3Y L;  3GTM L;  1K83 L;  4BY7 L;  2R93 L;  3RZO L;  2R7Z L;  2VUM L;  2E2J L;  4Y7N L;  2WB1 P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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