2E4OA

X-ray crystal structure of aristolochene synthase from aspergillus terreus and the evolution of templates for the cyclization of farnesyl diphosphate
Total Genus 118
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
118
sequence length
305
structure length
295
Chain Sequence
SLEPPPSTFQPLCHPLVEEVSKEVDGYFLQHWNFPNEKARKKFVAAGFSRVTCLYFPKALDDRIHFACRLLTVLFLIDDLLEYMSFEEGSAYNEKLIPISRGDVLPDRSIPVEYIIYDLWESMRAHDREMADEILEPVFLFMRAQTDRTRARPMGLGGYLEYRERDVGKELLAALMRFSMGLKLSPSELQRVREIDANCSKHLSVVNDIYSYEKELYTLCTSVQILAQEADVTAEAAKRVLFVMCREWELRHQLLVARLSAEGLETPGLAAYVEGLEYQMSGNELWSQTTLRYSV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray crystal structure of aristolochene synthase from Aspergillus terreus and evolution of templates for the cyclization of farnesyl diphosphate.
pubmed doi rcsb
molecule tags Lyase
source organism Aspergillus terreus
molecule keywords Aristolochene synthase
total genus 118
structure length 295
sequence length 305
chains with identical sequence B, C, D
ec nomenclature ec 4.2.3.9: Aristolochene synthase.
pdb deposition date 2006-12-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2e4oA00
2F89F 3ACYA 1VG7A 3LG5A 2AZKA 1DGPA 1WL0A 4UMJA 4WK5A 4XQSF 4RNQA 5DGNF 5IMIA 3OACB 4EA1A 3P41A 5B0MA 3CP6A 1N24A 5B02A 1V4KA 3WSAA 3OABB 3WCAA 5ERMA 5B0LA 2ZEUA 2PS5A 4EA0A 1V4HA 4GP2A 3VJ9A 4DI5A 3NF2A 4KKMA 3RMGA 2F8ZF 2F9KF 3SDQA 3N3DA 4KPJA 1KIYA 2E94A 3QQVA 3NPKA 1YYTA 4JXYA 3SAEA 4KWDA 4P0XA 3WCEA 2QISA 4P0VA 3RBMA 4JYXA 4LIXA 2F8CF 5E8KA 4DWGA 1N1ZA 4N1ZF 3WJOA 5DW7A 4LTZA 3EFQA 1VG2A 5A0JA 4KFAA 3AE0A 3QKCA 5ILJA 3ID0A 1YHKA 5HN8A 1PS1A 4GA3A 1UBXA 3M00A 3P8RA 3AQBB 3N45F 3CC9A 3PH7A 5IK9A 3WJKA 5IL3A 5I1UA 2ZY1A 2OGDA 4LZCA 3M02A 3LJIA 2OPMA 2ZCRA 3ZL6A 3LGKA 2P1CA 2Q80A 3P5PA 3ICZA 5EATA 2ZCSA 3APZA 5IKAA 4K10A 5HN9A 3RYWA 3KROA 2E8TA 1JFGA 1N22A 3KRFB 1VG3A 5DJVF 3WCIA 4PVXF 2E93A 2Z52A 5E8LA 3WCMA 4XQTF 3KRAA 4DEMF 3SDUA 3WEKA 4RXCA 2AZLA 3LZ9A 4KVDA 4H5DF 2F94F 2ZEVA 1RQJA 4DHDA 1HM7A 3Q1OA 4LTVA 3S9VA 3WCHA 2OA6A 5CG5A 3LK5A 5AYPA 4LZ0A 2J1OA 5DGSF 4KK2A 5A0KA 3LLWA 3KRPB 1YJ4A 4E1EA 4KVIA 2PS6A 3PKOA 1YYSA 2E8XA 1RQIA 5CG6A 5IMPA 1HXCA 1UBYA 2Z50A 3B7LA 5JA0F 2E8WA 2ZCOA 5IL8A 3LOMA 3Q2ZA 3TFNA 5DHIA 3KRCA 1WMWA 4LUUA 3LDWA 3DYGA 2I19A 3OYRA 1HXGA 2Q9ZA 4F62A 3P5RA 1HX9A 4GAXA 4HD1A 3ZMCA 1EZFA 1UBVA 4OKZA 3SDRA 2ZCQA 2Z4ZA 5IVGA 3N49F 3NPRA 3SDTA 5DHKA 2ONGA 4JXNA 4LA5A 3WSBA 1V4JA 3LEEA 1YQ7A 2E95A 5HNAA 3WEHA 4LA6A 1YHMA 5EROA 4NFIF 2Z4WA 4MC8A 3G4FA 5AELA 2H8OA 3VJAA 3KBKA 4QPFA 2J5CA 3MZVA 3N5JF 3WCDA 1ZW5A 3NRIA 2E92A 3SDVA 2RAHA 2E4OA 3ZOUA 5DJRF 2O1OA 1YYUA 4DWBA 1N1BA 1YYQA 5B03A 3OACA 4FP4A 3VJCA 4KQUA 4NG6A 4MC3A 3WCLA 1N23A 3AQCB 3IBAA 3OABA 3WCFA 1HXAA 2F92F 3Q2QA 3PDEA 4PVYF 3WEGA 5EAUA 4N9UA 4NFJF 2FTZA 3WCGA 2DH4A 2Z7HA 3N0GA 2F7MF 3UCAA 3WC9A 5ILKA 5IK0A 4EA2A 4F6VA 5EASA 5C05A 3IPIA 3W7FA 4RXAA 5JUZF 3VJDA 3N5HF 5JV1F 2E8VA 3N46F 3TFPA 5ILIA 3PYAA 5DIQF 5A0IA 3EGTA 2E8UA 2FORA 2ONHA 3EZ3A 4F6XA 1UBWA 4NFKF 1WL1A 2Q9YA 3DYHA 5KSXF 1N21A 5ER8A 3ICNA 3M01A 4NKFA 1HM4A 4H5CF 4RXEA 3M0GA 3ICKA 3BNXA 3N1WF 3N3LF 3KB9A 1YV5A 3ADZA 1FPSA 3ICMA 1DI1A 2OPNA 4LPGF 1YYRA 2AZJA 5AFXA 5DGMF 5B00A 3TS7A 4LPHF 3WEIA 5B0IA 4ZQ8A 3VJBA 4JZXA 3KRFA 4NKEA 5E8HA 3V1XA 1KIZA 2Z78A 1V4EA 5ILZA 3S4JA 2J1PA 2PS4A 3P8LA 2VF6A 3AQ0A 5H9DA 4E9ZA 3Q30A 5IKHA 4QXSF 3KROB 5ILDA 4KPDA 5DZ2A 3VJ8A 1WY0A 5IM1A 5DJPF 4E9UA 2E90A 2Z4XA 4L2XF 5JV0F 1N20A 3KRAB 3WEJA 2AELA 4NUAA 3WCJA 4KQSA 4XQRF 1VG4A 2PS7A 3KRPA 5IMNA 4DZWA 3VJEA 3LSNA 3M9UA 4LOBA 3WEFA 3N6KF 4LFEA 3V1VA 2Z7IA 4RYPA 3LMDA 2EWGA 4LZ3A 4GP1A 3ACXA 3LVSA 3N0FA 5ILYA 4OMGA 4RXDA 3MAVA 4LLTA 4JZBA 1RTRA 4KUXA 1WL2A 3CKEA 3WCBA 5AHUB 3KRCB 2AETA 1JFAA 3TFVA 3BNYA 5B01A 4KQ5A 3LGZB 1VG6A 4LXWA 4OGUA 3DYFA 5JV2F 4MC0A 3G4DA 2PS8A 2Q58A 3N1VF 3ASXA 1V4IA 4P0WA 5IN8A 3TC1A 3ZMBA 4KVYA 2AEKA 4LLSA 5B0KA 4H5EF 4KVWA 4LFVF 4OMHA 5IK6A 3ZCDA 4LFGA 3WJNA 2Z4YA 4Q23A 3ACWA 3PYBA 1WKZA 3RYEA 5ERNA 3WCCA 4OKMA 5B0JA 5ILHA 4DXJA 3WE9A 1YHLA 2E91A 5HN7A 3V66A 4JVJF 2Z4VA 4FJQA 1WL3A
chains in the Genus database with same CATH superfamily
2F89F 3ACYA 1VG7A 3LG5A 2AZKA 1DGPA 1WL0A 4UMJA 4WK5A 4XQSF 4RNQA 5DGNF 5IMIA 3OACB 4EA1A 3P41A 5B0MA 3CP6A 1N24A 5B02A 1V4KA 3WSAA 3OABB 3WCAA 5ERMA 5B0LA 2ZEUA 2PS5A 4EA0A 1V4HA 4GP2A 3VJ9A 4DI5A 3NF2A 4KKMA 3RMGA 2F8ZF 2F9KF 3SDQA 3N3DA 4KPJA 1KIYA 2E94A 3QQVA 3NPKA 1YYTA 4JXYA 3SAEA 4KWDA 4P0XA 3WCEA 2QISA 4P0VA 3RBMA 4JYXA 4LIXA 2F8CF 5E8KA 4DWGA 1N1ZA 4N1ZF 3WJOA 5DW7A 4LTZA 3EFQA 1VG2A 5A0JA 4KFAA 3AE0A 3QKCA 5ILJA 3ID0A 1YHKA 5HN8A 1PS1A 4GA3A 1UBXA 3M00A 3P8RA 3AQBB 3N45F 3CC9A 3PH7A 5IK9A 3WJKA 5IL3A 5I1UA 2ZY1A 2OGDA 4LZCA 3M02A 3LJIA 2OPMA 2ZCRA 3ZL6A 3LGKA 2P1CA 2Q80A 3P5PA 3ICZA 5EATA 2ZCSA 3APZA 5IKAA 4K10A 5HN9A 3RYWA 3KROA 2E8TA 1JFGA 1N22A 3KRFB 1VG3A 5DJVF 3WCIA 4PVXF 2E93A 2Z52A 5E8LA 3WCMA 4XQTF 3KRAA 4DEMF 3SDUA 3WEKA 4RXCA 2AZLA 3LZ9A 4KVDA 4H5DF 2F94F 2ZEVA 1RQJA 4DHDA 1HM7A 3Q1OA 4LTVA 3S9VA 3WCHA 2OA6A 5CG5A 3LK5A 5AYPA 4LZ0A 2J1OA 5DGSF 4KK2A 5A0KA 3LLWA 3KRPB 1YJ4A 4E1EA 4KVIA 2PS6A 3PKOA 1YYSA 2E8XA 1RQIA 5CG6A 5IMPA 1HXCA 1UBYA 2Z50A 3B7LA 5JA0F 2E8WA 2ZCOA 5IL8A 3LOMA 3Q2ZA 3TFNA 5DHIA 3KRCA 1WMWA 4LUUA 3LDWA 3DYGA 2I19A 3OYRA 1HXGA 2Q9ZA 4F62A 3P5RA 1HX9A 4GAXA 4HD1A 3ZMCA 1EZFA 1UBVA 4OKZA 3SDRA 2ZCQA 2Z4ZA 5IVGA 3N49F 3NPRA 3SDTA 5DHKA 2ONGA 4JXNA 4LA5A 3WSBA 1V4JA 3LEEA 1YQ7A 2E95A 5HNAA 3WEHA 4LA6A 1YHMA 5EROA 4NFIF 2Z4WA 4MC8A 3G4FA 5AELA 2H8OA 3VJAA 3KBKA 4QPFA 2J5CA 3MZVA 3N5JF 3WCDA 1ZW5A 3NRIA 2E92A 3SDVA 2RAHA 2E4OA 3ZOUA 5DJRF 2O1OA 1YYUA 4DWBA 1N1BA 1YYQA 5B03A 3OACA 4FP4A 3VJCA 4KQUA 4NG6A 4MC3A 3WCLA 1N23A 3AQCB 3IBAA 3OABA 3WCFA 1HXAA 2F92F 3Q2QA 3PDEA 4PVYF 3WEGA 5EAUA 4N9UA 4NFJF 2FTZA 3WCGA 2DH4A 2Z7HA 3N0GA 2F7MF 3UCAA 3WC9A 5ILKA 5IK0A 4EA2A 4F6VA 5EASA 5C05A 3IPIA 3W7FA 4RXAA 5JUZF 3VJDA 3N5HF 5JV1F 2E8VA 3N46F 3TFPA 5ILIA 3PYAA 5DIQF 5A0IA 3EGTA 2E8UA 2FORA 2ONHA 3EZ3A 4F6XA 1UBWA 4NFKF 1WL1A 2Q9YA 3DYHA 5KSXF 1N21A 5ER8A 3ICNA 3M01A 4NKFA 1HM4A 4H5CF 4RXEA 3M0GA 3ICKA 3BNXA 3N1WF 3N3LF 3KB9A 1YV5A 3ADZA 1FPSA 3ICMA 1DI1A 2OPNA 4LPGF 1YYRA 2AZJA 5AFXA 5DGMF 5B00A 3TS7A 4LPHF 3WEIA 5B0IA 4ZQ8A 3VJBA 4JZXA 3KRFA 4NKEA 5E8HA 3V1XA 1KIZA 2Z78A 1V4EA 5ILZA 3S4JA 2J1PA 2PS4A 3P8LA 2VF6A 3AQ0A 5H9DA 4E9ZA 3Q30A 5IKHA 4QXSF 3KROB 5ILDA 4KPDA 5DZ2A 3VJ8A 1WY0A 5IM1A 5DJPF 4E9UA 2E90A 2Z4XA 4L2XF 5JV0F 1N20A 3KRAB 3WEJA 2AELA 4NUAA 3WCJA 4KQSA 4XQRF 1VG4A 2PS7A 3KRPA 5IMNA 4DZWA 3VJEA 3LSNA 3M9UA 4LOBA 3WEFA 3N6KF 4LFEA 3V1VA 2Z7IA 4RYPA 3LMDA 2EWGA 4LZ3A 4GP1A 3ACXA 3LVSA 3N0FA 5ILYA 4OMGA 4RXDA 3MAVA 4LLTA 4JZBA 1RTRA 4KUXA 1WL2A 3CKEA 3WCBA 5AHUB 3KRCB 2AETA 1JFAA 3TFVA 3BNYA 5B01A 4KQ5A 3LGZB 1VG6A 4LXWA 4OGUA 3DYFA 5JV2F 4MC0A 3G4DA 2PS8A 2Q58A 3N1VF 3ASXA 1V4IA 4P0WA 5IN8A 3TC1A 3ZMBA 4KVYA 2AEKA 4LLSA 5B0KA 4H5EF 4KVWA 4LFVF 4OMHA 5IK6A 3ZCDA 4LFGA 3WJNA 2Z4YA 4Q23A 3ACWA 3PYBA 1WKZA 3RYEA 5ERNA 3WCCA 4OKMA 5B0JA 5ILHA 4DXJA 3WE9A 1YHLA 2E91A 5HN7A 3V66A 4JVJF 2Z4VA 4FJQA 1WL3A
chains in the Genus database with same CATH topology
2F89F 3ACYA 1VG7A 3LG5A 2AZKA 1DGPA 1WL0A 4UMJA 4WK5A 4XQSF 4RNQA 5DGNF 5IMIA 3OACB 4EA1A 3P41A 5B0MA 3CP6A 1N24A 5B02A 1V4KA 3WSAA 3OABB 3WCAA 5ERMA 5B0LA 2ZEUA 2PS5A 4EA0A 1V4HA 4GP2A 3VJ9A 4DI5A 3NF2A 4KKMA 3RMGA 2F8ZF 2F9KF 3SDQA 3N3DA 4KPJA 1KIYA 2E94A 3QQVA 3NPKA 1YYTA 4JXYA 3SAEA 4KWDA 4P0XA 3WCEA 2QISA 4P0VA 3RBMA 4JYXA 4LIXA 2F8CF 5E8KA 4DWGA 1N1ZA 4N1ZF 3WJOA 5DW7A 4LTZA 3EFQA 1VG2A 5A0JA 4KFAA 3AE0A 3QKCA 5ILJA 3ID0A 1YHKA 5HN8A 1PS1A 4GA3A 1UBXA 3M00A 3P8RA 3AQBB 3N45F 3CC9A 3PH7A 5IK9A 3WJKA 5IL3A 5I1UA 2ZY1A 2OGDA 4LZCA 3M02A 3LJIA 2OPMA 2ZCRA 3ZL6A 3LGKA 2P1CA 2Q80A 3P5PA 3ICZA 5EATA 2ZCSA 3APZA 5IKAA 4K10A 5HN9A 3RYWA 3KROA 2E8TA 1JFGA 1N22A 3KRFB 1VG3A 5DJVF 3WCIA 4PVXF 2E93A 2Z52A 5E8LA 3WCMA 4XQTF 3KRAA 4DEMF 3SDUA 3WEKA 4RXCA 2AZLA 3LZ9A 4KVDA 4H5DF 2F94F 2ZEVA 1RQJA 4DHDA 1HM7A 3Q1OA 4LTVA 3S9VA 3WCHA 2OA6A 5CG5A 3LK5A 5AYPA 4LZ0A 2J1OA 5DGSF 4KK2A 5A0KA 3LLWA 3KRPB 1YJ4A 4E1EA 4KVIA 2PS6A 3PKOA 1YYSA 2E8XA 1RQIA 5CG6A 5IMPA 1HXCA 1UBYA 2Z50A 3B7LA 5JA0F 2E8WA 2ZCOA 5IL8A 3LOMA 3Q2ZA 3TFNA 5DHIA 3KRCA 1WMWA 4LUUA 3LDWA 3DYGA 2I19A 3OYRA 1HXGA 2Q9ZA 4F62A 3P5RA 1HX9A 4GAXA 4HD1A 3ZMCA 1EZFA 1UBVA 4OKZA 3SDRA 2ZCQA 2Z4ZA 5IVGA 3N49F 3NPRA 3SDTA 5DHKA 2ONGA 4JXNA 4LA5A 3WSBA 1V4JA 3LEEA 1YQ7A 2E95A 5HNAA 3WEHA 4LA6A 1YHMA 5EROA 4NFIF 2Z4WA 4MC8A 3G4FA 5AELA 2H8OA 3VJAA 3KBKA 4QPFA 2J5CA 3MZVA 3N5JF 3WCDA 1ZW5A 3NRIA 2E92A 3SDVA 2RAHA 2E4OA 3ZOUA 5DJRF 2O1OA 1YYUA 4DWBA 1N1BA 1YYQA 5B03A 3OACA 4FP4A 3VJCA 4KQUA 4NG6A 4MC3A 3WCLA 1N23A 3AQCB 3IBAA 3OABA 3WCFA 1HXAA 2F92F 3Q2QA 3PDEA 4PVYF 3WEGA 5EAUA 4N9UA 4NFJF 2FTZA 3WCGA 2DH4A 2Z7HA 3N0GA 2F7MF 3UCAA 3WC9A 5ILKA 5IK0A 4EA2A 4F6VA 5EASA 5C05A 3IPIA 3W7FA 4RXAA 5JUZF 3VJDA 3N5HF 5JV1F 2E8VA 3N46F 3TFPA 5ILIA 3PYAA 5DIQF 5A0IA 3EGTA 2E8UA 2FORA 2ONHA 3EZ3A 4F6XA 1UBWA 4NFKF 1WL1A 2Q9YA 3DYHA 5KSXF 1N21A 5ER8A 3ICNA 3M01A 4NKFA 1HM4A 4H5CF 4RXEA 3M0GA 3ICKA 3BNXA 3N1WF 3N3LF 3KB9A 1YV5A 3ADZA 1FPSA 3ICMA 1DI1A 2OPNA 4LPGF 1YYRA 2AZJA 5AFXA 5DGMF 5B00A 3TS7A 4LPHF 3WEIA 5B0IA 4ZQ8A 3VJBA 4JZXA 3KRFA 4NKEA 5E8HA 3V1XA 1KIZA 2Z78A 1V4EA 5ILZA 3S4JA 2J1PA 2PS4A 3P8LA 2VF6A 3AQ0A 5H9DA 4E9ZA 3Q30A 5IKHA 4QXSF 3KROB 5ILDA 4KPDA 5DZ2A 3VJ8A 1WY0A 5IM1A 5DJPF 4E9UA 2E90A 2Z4XA 4L2XF 5JV0F 1N20A 3KRAB 3WEJA 2AELA 4NUAA 3WCJA 4KQSA 4XQRF 1VG4A 2PS7A 3KRPA 5IMNA 4DZWA 3VJEA 3LSNA 3M9UA 4LOBA 3WEFA 3N6KF 4LFEA 3V1VA 2Z7IA 4RYPA 3LMDA 2EWGA 4LZ3A 4GP1A 3ACXA 3LVSA 3N0FA 5ILYA 4OMGA 4RXDA 3MAVA 4LLTA 4JZBA 1RTRA 4KUXA 1WL2A 3CKEA 3WCBA 5AHUB 3KRCB 2AETA 1JFAA 3TFVA 3BNYA 5B01A 4KQ5A 3LGZB 1VG6A 4LXWA 4OGUA 3DYFA 5JV2F 4MC0A 3G4DA 2PS8A 2Q58A 3N1VF 3ASXA 1V4IA 4P0WA 5IN8A 3TC1A 3ZMBA 4KVYA 2AEKA 4LLSA 5B0KA 4H5EF 4KVWA 4LFVF 4OMHA 5IK6A 3ZCDA 4LFGA 3WJNA 2Z4YA 4Q23A 3ACWA 3PYBA 1WKZA 3RYEA 5ERNA 3WCCA 4OKMA 5B0JA 5ILHA 4DXJA 3WE9A 1YHLA 2E91A 5HN7A 3V66A 4JVJF 2Z4VA 4FJQA 1WL3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F89 F;  3ACY A;  1VG7 A;  3LG5 A;  2AZK A;  1DGP A;  1WL0 A;  4UMJ A;  4WK5 A;  4XQS F;  4RNQ A;  5DGN F;  5IMI A;  3OAC B;  4EA1 A;  3P41 A;  5B0M A;  3CP6 A;  1N24 A;  5B02 A;  1V4K A;  3WSA A;  3OAB B;  3WCA A;  5ERM A;  5B0L A;  2ZEU A;  2PS5 A;  4EA0 A;  1V4H A;  4GP2 A;  3VJ9 A;  4DI5 A;  3NF2 A;  4KKM A;  3RMG A;  2F8Z F;  2F9K F;  3SDQ A;  3N3D A;  4KPJ A;  1KIY A;  2E94 A;  3QQV A;  3NPK A;  1YYT A;  4JXY A;  3SAE A;  4KWD A;  4P0X A;  3WCE A;  2QIS A;  4P0V A;  3RBM A;  4JYX A;  4LIX A;  2F8C F;  5E8K A;  4DWG A;  1N1Z A;  4N1Z F;  3WJO A;  5DW7 A;  4LTZ A;  3EFQ A;  1VG2 A;  5A0J A;  4KFA A;  3AE0 A;  3QKC A;  5ILJ A;  3ID0 A;  1YHK A;  5HN8 A;  1PS1 A;  4GA3 A;  1UBX A;  3M00 A;  3P8R A;  3AQB B;  3N45 F;  3CC9 A;  3PH7 A;  5IK9 A;  3WJK A;  5IL3 A;  5I1U A;  2ZY1 A;  2OGD A;  4LZC A;  3M02 A;  3LJI A;  2OPM A;  2ZCR A;  3ZL6 A;  3LGK A;  2P1C A;  2Q80 A;  3P5P A;  3ICZ A;  5EAT A;  2ZCS A;  3APZ A;  5IKA A;  4K10 A;  5HN9 A;  3RYW A;  3KRO A;  2E8T A;  1JFG A;  1N22 A;  3KRF B;  1VG3 A;  5DJV F;  3WCI A;  4PVX F;  2E93 A;  2Z52 A;  5E8L A;  3WCM A;  4XQT F;  3KRA A;  4DEM F;  3SDU A;  3WEK A;  4RXC A;  2AZL A;  3LZ9 A;  4KVD A;  4H5D F;  2F94 F;  2ZEV A;  1RQJ A;  4DHD A;  1HM7 A;  3Q1O A;  4LTV A;  3S9V A;  3WCH A;  2OA6 A;  5CG5 A;  3LK5 A;  5AYP A;  4LZ0 A;  2J1O A;  5DGS F;  4KK2 A;  5A0K A;  3LLW A;  3KRP B;  1YJ4 A;  4E1E A;  4KVI A;  2PS6 A;  3PKO A;  1YYS A;  2E8X A;  1RQI A;  5CG6 A;  5IMP A;  1HXC A;  1UBY A;  2Z50 A;  3B7L A;  5JA0 F;  2E8W A;  2ZCO A;  5IL8 A;  3LOM A;  3Q2Z A;  3TFN A;  5DHI A;  3KRC A;  1WMW A;  4LUU A;  3LDW A;  3DYG A;  2I19 A;  3OYR A;  1HXG A;  2Q9Z A;  4F62 A;  3P5R A;  1HX9 A;  4GAX A;  4HD1 A;  3ZMC A;  1EZF A;  1UBV A;  4OKZ A;  3SDR A;  2ZCQ A;  2Z4Z A;  5IVG A;  3N49 F;  3NPR A;  3SDT A;  5DHK A;  2ONG A;  4JXN A;  4LA5 A;  3WSB A;  1V4J A;  3LEE A;  1YQ7 A;  2E95 A;  5HNA A;  3WEH A;  4LA6 A;  1YHM A;  5ERO A;  4NFI F;  2Z4W A;  4MC8 A;  3G4F A;  5AEL A;  2H8O A;  3VJA A;  3KBK A;  4QPF A;  2J5C A;  3MZV A;  3N5J F;  3WCD A;  1ZW5 A;  3NRI A;  2E92 A;  3SDV A;  2RAH A;  2E4O A;  3ZOU A;  5DJR F;  2O1O A;  1YYU A;  4DWB A;  1N1B A;  1YYQ A;  5B03 A;  3OAC A;  4FP4 A;  3VJC A;  4KQU A;  4NG6 A;  4MC3 A;  3WCL A;  1N23 A;  3AQC B;  3IBA A;  3OAB A;  3WCF A;  1HXA A;  2F92 F;  3Q2Q A;  3PDE A;  4PVY F;  3WEG A;  5EAU A;  4N9U A;  4NFJ F;  2FTZ A;  3WCG A;  2DH4 A;  2Z7H A;  3N0G A;  2F7M F;  3UCA A;  3WC9 A;  5ILK A;  5IK0 A;  4EA2 A;  4F6V A;  5EAS A;  5C05 A;  3IPI A;  3W7F A;  4RXA A;  5JUZ F;  3VJD A;  3N5H F;  5JV1 F;  2E8V A;  3N46 F;  3TFP A;  5ILI A;  3PYA A;  5DIQ F;  5A0I A;  3EGT A;  2E8U A;  2FOR A;  2ONH A;  3EZ3 A;  4F6X A;  1UBW A;  4NFK F;  1WL1 A;  2Q9Y A;  3DYH A;  5KSX F;  1N21 A;  5ER8 A;  3ICN A;  3M01 A;  4NKF A;  1HM4 A;  4H5C F;  4RXE A;  3M0G A;  3ICK A;  3BNX A;  3N1W F;  3N3L F;  3KB9 A;  1YV5 A;  3ADZ A;  1FPS A;  3ICM A;  1DI1 A;  2OPN A;  4LPG F;  1YYR A;  2AZJ A;  5AFX A;  5DGM F;  5B00 A;  3TS7 A;  4LPH F;  3WEI A;  5B0I A;  4ZQ8 A;  3VJB A;  4JZX A;  3KRF A;  4NKE A;  5E8H A;  3V1X A;  1KIZ A;  2Z78 A;  1V4E A;  5ILZ A;  3S4J A;  2J1P A;  2PS4 A;  3P8L A;  2VF6 A;  3AQ0 A;  5H9D A;  4E9Z A;  3Q30 A;  5IKH A;  4QXS F;  3KRO B;  5ILD A;  4KPD A;  5DZ2 A;  3VJ8 A;  1WY0 A;  5IM1 A;  5DJP F;  4E9U A;  2E90 A;  2Z4X A;  4L2X F;  5JV0 F;  1N20 A;  3KRA B;  3WEJ A;  2AEL A;  4NUA A;  3WCJ A;  4KQS A;  4XQR F;  1VG4 A;  2PS7 A;  3KRP A;  5IMN A;  4DZW A;  3VJE A;  3LSN A;  3M9U A;  4LOB A;  3WEF A;  3N6K F;  4LFE A;  3V1V A;  2Z7I A;  4RYP A;  3LMD A;  2EWG A;  4LZ3 A;  4GP1 A;  3ACX A;  3LVS A;  3N0F A;  5ILY A;  4OMG A;  4RXD A;  3MAV A;  4LLT A;  4JZB A;  1RTR A;  4KUX A;  1WL2 A;  3CKE A;  3WCB A;  5AHU B;  3KRC B;  2AET A;  1JFA A;  3TFV A;  3BNY A;  5B01 A;  4KQ5 A;  3LGZ B;  1VG6 A;  4LXW A;  4OGU A;  3DYF A;  5JV2 F;  4MC0 A;  3G4D A;  2PS8 A;  2Q58 A;  3N1V F;  3ASX A;  1V4I A;  4P0W A;  5IN8 A;  3TC1 A;  3ZMB A;  4KVY A;  2AEK A;  4LLS A;  5B0K A;  4H5E F;  4KVW A;  4LFV F;  4OMH A;  5IK6 A;  3ZCD A;  4LFG A;  3WJN A;  2Z4Y A;  4Q23 A;  3ACW A;  3PYB A;  1WKZ A;  3RYE A;  5ERN A;  3WCC A;  4OKM A;  5B0J A;  5ILH A;  4DXJ A;  3WE9 A;  1YHL A;  2E91 A;  5HN7 A;  3V66 A;  4JVJ F;  2Z4V A;  4FJQ A;  1WL3 A; 
#chains in the Genus database with same CATH topology
 2F89 F;  3ACY A;  1VG7 A;  3LG5 A;  2AZK A;  1DGP A;  1WL0 A;  4UMJ A;  4WK5 A;  4XQS F;  4RNQ A;  5DGN F;  5IMI A;  3OAC B;  4EA1 A;  3P41 A;  5B0M A;  3CP6 A;  1N24 A;  5B02 A;  1V4K A;  3WSA A;  3OAB B;  3WCA A;  5ERM A;  5B0L A;  2ZEU A;  2PS5 A;  4EA0 A;  1V4H A;  4GP2 A;  3VJ9 A;  4DI5 A;  3NF2 A;  4KKM A;  3RMG A;  2F8Z F;  2F9K F;  3SDQ A;  3N3D A;  4KPJ A;  1KIY A;  2E94 A;  3QQV A;  3NPK A;  1YYT A;  4JXY A;  3SAE A;  4KWD A;  4P0X A;  3WCE A;  2QIS A;  4P0V A;  3RBM A;  4JYX A;  4LIX A;  2F8C F;  5E8K A;  4DWG A;  1N1Z A;  4N1Z F;  3WJO A;  5DW7 A;  4LTZ A;  3EFQ A;  1VG2 A;  5A0J A;  4KFA A;  3AE0 A;  3QKC A;  5ILJ A;  3ID0 A;  1YHK A;  5HN8 A;  1PS1 A;  4GA3 A;  1UBX A;  3M00 A;  3P8R A;  3AQB B;  3N45 F;  3CC9 A;  3PH7 A;  5IK9 A;  3WJK A;  5IL3 A;  5I1U A;  2ZY1 A;  2OGD A;  4LZC A;  3M02 A;  3LJI A;  2OPM A;  2ZCR A;  3ZL6 A;  3LGK A;  2P1C A;  2Q80 A;  3P5P A;  3ICZ A;  5EAT A;  2ZCS A;  3APZ A;  5IKA A;  4K10 A;  5HN9 A;  3RYW A;  3KRO A;  2E8T A;  1JFG A;  1N22 A;  3KRF B;  1VG3 A;  5DJV F;  3WCI A;  4PVX F;  2E93 A;  2Z52 A;  5E8L A;  3WCM A;  4XQT F;  3KRA A;  4DEM F;  3SDU A;  3WEK A;  4RXC A;  2AZL A;  3LZ9 A;  4KVD A;  4H5D F;  2F94 F;  2ZEV A;  1RQJ A;  4DHD A;  1HM7 A;  3Q1O A;  4LTV A;  3S9V A;  3WCH A;  2OA6 A;  5CG5 A;  3LK5 A;  5AYP A;  4LZ0 A;  2J1O A;  5DGS F;  4KK2 A;  5A0K A;  3LLW A;  3KRP B;  1YJ4 A;  4E1E A;  4KVI A;  2PS6 A;  3PKO A;  1YYS A;  2E8X A;  1RQI A;  5CG6 A;  5IMP A;  1HXC A;  1UBY A;  2Z50 A;  3B7L A;  5JA0 F;  2E8W A;  2ZCO A;  5IL8 A;  3LOM A;  3Q2Z A;  3TFN A;  5DHI A;  3KRC A;  1WMW A;  4LUU A;  3LDW A;  3DYG A;  2I19 A;  3OYR A;  1HXG A;  2Q9Z A;  4F62 A;  3P5R A;  1HX9 A;  4GAX A;  4HD1 A;  3ZMC A;  1EZF A;  1UBV A;  4OKZ A;  3SDR A;  2ZCQ A;  2Z4Z A;  5IVG A;  3N49 F;  3NPR A;  3SDT A;  5DHK A;  2ONG A;  4JXN A;  4LA5 A;  3WSB A;  1V4J A;  3LEE A;  1YQ7 A;  2E95 A;  5HNA A;  3WEH A;  4LA6 A;  1YHM A;  5ERO A;  4NFI F;  2Z4W A;  4MC8 A;  3G4F A;  5AEL A;  2H8O A;  3VJA A;  3KBK A;  4QPF A;  2J5C A;  3MZV A;  3N5J F;  3WCD A;  1ZW5 A;  3NRI A;  2E92 A;  3SDV A;  2RAH A;  2E4O A;  3ZOU A;  5DJR F;  2O1O A;  1YYU A;  4DWB A;  1N1B A;  1YYQ A;  5B03 A;  3OAC A;  4FP4 A;  3VJC A;  4KQU A;  4NG6 A;  4MC3 A;  3WCL A;  1N23 A;  3AQC B;  3IBA A;  3OAB A;  3WCF A;  1HXA A;  2F92 F;  3Q2Q A;  3PDE A;  4PVY F;  3WEG A;  5EAU A;  4N9U A;  4NFJ F;  2FTZ A;  3WCG A;  2DH4 A;  2Z7H A;  3N0G A;  2F7M F;  3UCA A;  3WC9 A;  5ILK A;  5IK0 A;  4EA2 A;  4F6V A;  5EAS A;  5C05 A;  3IPI A;  3W7F A;  4RXA A;  5JUZ F;  3VJD A;  3N5H F;  5JV1 F;  2E8V A;  3N46 F;  3TFP A;  5ILI A;  3PYA A;  5DIQ F;  5A0I A;  3EGT A;  2E8U A;  2FOR A;  2ONH A;  3EZ3 A;  4F6X A;  1UBW A;  4NFK F;  1WL1 A;  2Q9Y A;  3DYH A;  5KSX F;  1N21 A;  5ER8 A;  3ICN A;  3M01 A;  4NKF A;  1HM4 A;  4H5C F;  4RXE A;  3M0G A;  3ICK A;  3BNX A;  3N1W F;  3N3L F;  3KB9 A;  1YV5 A;  3ADZ A;  1FPS A;  3ICM A;  1DI1 A;  2OPN A;  4LPG F;  1YYR A;  2AZJ A;  5AFX A;  5DGM F;  5B00 A;  3TS7 A;  4LPH F;  3WEI A;  5B0I A;  4ZQ8 A;  3VJB A;  4JZX A;  3KRF A;  4NKE A;  5E8H A;  3V1X A;  1KIZ A;  2Z78 A;  1V4E A;  5ILZ A;  3S4J A;  2J1P A;  2PS4 A;  3P8L A;  2VF6 A;  3AQ0 A;  5H9D A;  4E9Z A;  3Q30 A;  5IKH A;  4QXS F;  3KRO B;  5ILD A;  4KPD A;  5DZ2 A;  3VJ8 A;  1WY0 A;  5IM1 A;  5DJP F;  4E9U A;  2E90 A;  2Z4X A;  4L2X F;  5JV0 F;  1N20 A;  3KRA B;  3WEJ A;  2AEL A;  4NUA A;  3WCJ A;  4KQS A;  4XQR F;  1VG4 A;  2PS7 A;  3KRP A;  5IMN A;  4DZW A;  3VJE A;  3LSN A;  3M9U A;  4LOB A;  3WEF A;  3N6K F;  4LFE A;  3V1V A;  2Z7I A;  4RYP A;  3LMD A;  2EWG A;  4LZ3 A;  4GP1 A;  3ACX A;  3LVS A;  3N0F A;  5ILY A;  4OMG A;  4RXD A;  3MAV A;  4LLT A;  4JZB A;  1RTR A;  4KUX A;  1WL2 A;  3CKE A;  3WCB A;  5AHU B;  3KRC B;  2AET A;  1JFA A;  3TFV A;  3BNY A;  5B01 A;  4KQ5 A;  3LGZ B;  1VG6 A;  4LXW A;  4OGU A;  3DYF A;  5JV2 F;  4MC0 A;  3G4D A;  2PS8 A;  2Q58 A;  3N1V F;  3ASX A;  1V4I A;  4P0W A;  5IN8 A;  3TC1 A;  3ZMB A;  4KVY A;  2AEK A;  4LLS A;  5B0K A;  4H5E F;  4KVW A;  4LFV F;  4OMH A;  5IK6 A;  3ZCD A;  4LFG A;  3WJN A;  2Z4Y A;  4Q23 A;  3ACW A;  3PYB A;  1WKZ A;  3RYE A;  5ERN A;  3WCC A;  4OKM A;  5B0J A;  5ILH A;  4DXJ A;  3WE9 A;  1YHL A;  2E91 A;  5HN7 A;  3V66 A;  4JVJ F;  2Z4V A;  4FJQ A;  1WL3 A; 
#chains in the Genus database with same CATH homology
 2F89 F;  3ACY A;  1VG7 A;  3LG5 A;  2AZK A;  1DGP A;  1WL0 A;  4UMJ A;  4WK5 A;  4XQS F;  4RNQ A;  5DGN F;  5IMI A;  3OAC B;  4EA1 A;  3P41 A;  5B0M A;  3CP6 A;  1N24 A;  5B02 A;  1V4K A;  3WSA A;  3OAB B;  3WCA A;  5ERM A;  5B0L A;  2ZEU A;  2PS5 A;  4EA0 A;  1V4H A;  4GP2 A;  3VJ9 A;  4DI5 A;  3NF2 A;  4KKM A;  3RMG A;  2F8Z F;  2F9K F;  3SDQ A;  3N3D A;  4KPJ A;  1KIY A;  2E94 A;  3QQV A;  3NPK A;  1YYT A;  4JXY A;  3SAE A;  4KWD A;  4P0X A;  3WCE A;  2QIS A;  4P0V A;  3RBM A;  4JYX A;  4LIX A;  2F8C F;  5E8K A;  4DWG A;  1N1Z A;  4N1Z F;  3WJO A;  5DW7 A;  4LTZ A;  3EFQ A;  1VG2 A;  5A0J A;  4KFA A;  3AE0 A;  3QKC A;  5ILJ A;  3ID0 A;  1YHK A;  5HN8 A;  1PS1 A;  4GA3 A;  1UBX A;  3M00 A;  3P8R A;  3AQB B;  3N45 F;  3CC9 A;  3PH7 A;  5IK9 A;  3WJK A;  5IL3 A;  5I1U A;  2ZY1 A;  2OGD A;  4LZC A;  3M02 A;  3LJI A;  2OPM A;  2ZCR A;  3ZL6 A;  3LGK A;  2P1C A;  2Q80 A;  3P5P A;  3ICZ A;  5EAT A;  2ZCS A;  3APZ A;  5IKA A;  4K10 A;  5HN9 A;  3RYW A;  3KRO A;  2E8T A;  1JFG A;  1N22 A;  3KRF B;  1VG3 A;  5DJV F;  3WCI A;  4PVX F;  2E93 A;  2Z52 A;  5E8L A;  3WCM A;  4XQT F;  3KRA A;  4DEM F;  3SDU A;  3WEK A;  4RXC A;  2AZL A;  3LZ9 A;  4KVD A;  4H5D F;  2F94 F;  2ZEV A;  1RQJ A;  4DHD A;  1HM7 A;  3Q1O A;  4LTV A;  3S9V A;  3WCH A;  2OA6 A;  5CG5 A;  3LK5 A;  5AYP A;  4LZ0 A;  2J1O A;  5DGS F;  4KK2 A;  5A0K A;  3LLW A;  3KRP B;  1YJ4 A;  4E1E A;  4KVI A;  2PS6 A;  3PKO A;  1YYS A;  2E8X A;  1RQI A;  5CG6 A;  5IMP A;  1HXC A;  1UBY A;  2Z50 A;  3B7L A;  5JA0 F;  2E8W A;  2ZCO A;  5IL8 A;  3LOM A;  3Q2Z A;  3TFN A;  5DHI A;  3KRC A;  1WMW A;  4LUU A;  3LDW A;  3DYG A;  2I19 A;  3OYR A;  1HXG A;  2Q9Z A;  4F62 A;  3P5R A;  1HX9 A;  4GAX A;  4HD1 A;  3ZMC A;  1EZF A;  1UBV A;  4OKZ A;  3SDR A;  2ZCQ A;  2Z4Z A;  5IVG A;  3N49 F;  3NPR A;  3SDT A;  5DHK A;  2ONG A;  4JXN A;  4LA5 A;  3WSB A;  1V4J A;  3LEE A;  1YQ7 A;  2E95 A;  5HNA A;  3WEH A;  4LA6 A;  1YHM A;  5ERO A;  4NFI F;  2Z4W A;  4MC8 A;  3G4F A;  5AEL A;  2H8O A;  3VJA A;  3KBK A;  4QPF A;  2J5C A;  3MZV A;  3N5J F;  3WCD A;  1ZW5 A;  3NRI A;  2E92 A;  3SDV A;  2RAH A;  2E4O A;  3ZOU A;  5DJR F;  2O1O A;  1YYU A;  4DWB A;  1N1B A;  1YYQ A;  5B03 A;  3OAC A;  4FP4 A;  3VJC A;  4KQU A;  4NG6 A;  4MC3 A;  3WCL A;  1N23 A;  3AQC B;  3IBA A;  3OAB A;  3WCF A;  1HXA A;  2F92 F;  3Q2Q A;  3PDE A;  4PVY F;  3WEG A;  5EAU A;  4N9U A;  4NFJ F;  2FTZ A;  3WCG A;  2DH4 A;  2Z7H A;  3N0G A;  2F7M F;  3UCA A;  3WC9 A;  5ILK A;  5IK0 A;  4EA2 A;  4F6V A;  5EAS A;  5C05 A;  3IPI A;  3W7F A;  4RXA A;  5JUZ F;  3VJD A;  3N5H F;  5JV1 F;  2E8V A;  3N46 F;  3TFP A;  5ILI A;  3PYA A;  5DIQ F;  5A0I A;  3EGT A;  2E8U A;  2FOR A;  2ONH A;  3EZ3 A;  4F6X A;  1UBW A;  4NFK F;  1WL1 A;  2Q9Y A;  3DYH A;  5KSX F;  1N21 A;  5ER8 A;  3ICN A;  3M01 A;  4NKF A;  1HM4 A;  4H5C F;  4RXE A;  3M0G A;  3ICK A;  3BNX A;  3N1W F;  3N3L F;  3KB9 A;  1YV5 A;  3ADZ A;  1FPS A;  3ICM A;  1DI1 A;  2OPN A;  4LPG F;  1YYR A;  2AZJ A;  5AFX A;  5DGM F;  5B00 A;  3TS7 A;  4LPH F;  3WEI A;  5B0I A;  4ZQ8 A;  3VJB A;  4JZX A;  3KRF A;  4NKE A;  5E8H A;  3V1X A;  1KIZ A;  2Z78 A;  1V4E A;  5ILZ A;  3S4J A;  2J1P A;  2PS4 A;  3P8L A;  2VF6 A;  3AQ0 A;  5H9D A;  4E9Z A;  3Q30 A;  5IKH A;  4QXS F;  3KRO B;  5ILD A;  4KPD A;  5DZ2 A;  3VJ8 A;  1WY0 A;  5IM1 A;  5DJP F;  4E9U A;  2E90 A;  2Z4X A;  4L2X F;  5JV0 F;  1N20 A;  3KRA B;  3WEJ A;  2AEL A;  4NUA A;  3WCJ A;  4KQS A;  4XQR F;  1VG4 A;  2PS7 A;  3KRP A;  5IMN A;  4DZW A;  3VJE A;  3LSN A;  3M9U A;  4LOB A;  3WEF A;  3N6K F;  4LFE A;  3V1V A;  2Z7I A;  4RYP A;  3LMD A;  2EWG A;  4LZ3 A;  4GP1 A;  3ACX A;  3LVS A;  3N0F A;  5ILY A;  4OMG A;  4RXD A;  3MAV A;  4LLT A;  4JZB A;  1RTR A;  4KUX A;  1WL2 A;  3CKE A;  3WCB A;  5AHU B;  3KRC B;  2AET A;  1JFA A;  3TFV A;  3BNY A;  5B01 A;  4KQ5 A;  3LGZ B;  1VG6 A;  4LXW A;  4OGU A;  3DYF A;  5JV2 F;  4MC0 A;  3G4D A;  2PS8 A;  2Q58 A;  3N1V F;  3ASX A;  1V4I A;  4P0W A;  5IN8 A;  3TC1 A;  3ZMB A;  4KVY A;  2AEK A;  4LLS A;  5B0K A;  4H5E F;  4KVW A;  4LFV F;  4OMH A;  5IK6 A;  3ZCD A;  4LFG A;  3WJN A;  2Z4Y A;  4Q23 A;  3ACW A;  3PYB A;  1WKZ A;  3RYE A;  5ERN A;  3WCC A;  4OKM A;  5B0J A;  5ILH A;  4DXJ A;  3WE9 A;  1YHL A;  2E91 A;  5HN7 A;  3V66 A;  4JVJ F;  2Z4V A;  4FJQ A;  1WL3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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