2E7RA

Crystal structure of glu54 to arg mutant of diphthine synthase
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKRIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2007-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2e7rA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2e7rA01
1S4DA 2CBFA 2PCGA 2QBUA 2PB4A 2EHCA 1WNGA 2ELEA 2OWGA 2PCAA 1VCEA 2ED5A 1CBFA 1VHVA 3KWPA 3NEIA 2ED3A 2PB5A 2BB3A 2DV7A 2PCHA 2E17A 2PCKA 1PJTA 2EK4A 2ELDA 1V9AA 2EH2A 2EH5A 2E7RA 2EJJA 2HUTA 2OWKA 2EMUA 2EH4A 2EGLA 2EJKA 2PB6A 2EGSA 2EKAA 1PJSA 2EK3A 2E15A 2E08A 2DV4A 2DSGA 1VA0A 2EK2A 2DV3A 2P6KA 2P6LA 2OWFA 2ZVBA 1WDEA 1VE2A 2EN5A 2EL2A 2YBOA 2OWVA 3HH1A 2EGBA 2NPNA 2DEKA 2HR8A 3I4TA 2E0KA 3NDCA 2EL3A 2PCIA 2DXVA 2E8RA 1WYZA 2EHLA 2P9DA 3NUTA 2E8SA 2EEQA 2DXWA 2YBQA 2E16A 2EMRA 3ND1A 2E8HA 2E07A 2E4NA 2P6DA 2HUXA 2E4RA 2DSIA 3FFYA 2EL1A 2OWUA 2P6IA 3FQ6A 2EL0A 2EK7A 5HW4A 2P5FA 2HUQA 2DXXA 2PCMA 2E0NA 2E8QA 2P5CA 2P2XA 2DSHA 2HUVA 2Z6RA 2EJZA 2ZVCA 1PJQA 2ENIA 2DV5A 4E16A
chains in the Genus database with same CATH superfamily
1S4DA 3T0GA 2CBFA 2PCGA 2QBUA 2PB4A 2EHCA 1WNGA 2ELEA 2OWGA 2PCAA 1VCEA 2ED5A 4MV0A 1CBFA 1VHVA 3KWPA 3NEIA 2ED3A 2PB5A 2BB3A 4N7BA 2DV7A 3KELA 2PCHA 2E17A 2PCKA 1PJTA 2EK4A 3DNFA 2ELDA 3TIXB 3KEFA 1V9AA 2EH2A 2EH5A 2E7RA 2EJJA 4MUYA 2HUTA 2OWKA 3UTDA 2EMUA 2EH4A 2EGLA 3F7TA 3SZUA 2EJKA 2PB6A 2EGSA 2EKAA 4H4DA 1PJSA 2EK3A 2E15A 2E08A 2DV4A 2DSGA 1VA0A 2EK2A 4H4CA 2DV3A 2P6KA 2P6LA 2OWFA 2ZVBA 1WDEA 1VE2A 2EN5A 3KEMA 3UTCA 2EL2A 2YBOA 2OWVA 3HH1A 2EGBA 2NPNA 3KE9A 2DEKA 3ZGLA 2HR8A 3I4TA 2E0KA 3NDCA 3UWMA 2EL3A 3KE8A 2PCIA 2DXVA 2E8RA 1WYZA 2EHLA 2P9DA 3NUTA 2E8SA 2EEQA 3UV7A 2DXWA 2YBQA 2E16A 3UV6A 2EMRA 3ND1A 3UV3A 2E8HA 3ZGNA 2E07A 3LMMA 2E4NA 2P6DA 2HUXA 2E4RA 2DSIA 3FFYA 2EL1A 2OWUA 2P6IA 3FQ6A 2EL0A 4EB3A 3SZLA 2EK7A 5HW4A 2P5FA 4MUXA 2HUQA 2DXXA 2PCMA 3T0FA 2E0NA 2E8QA 2P5CA 4MV5A 2P2XA 3SZOA 2DSHA 2HUVA 2Z6RA 2EJZA 2KYYA 4H4EA 3URKA 2ZVCA 1PJQA 2ENIA 2DV5A 4E16A
chains in the Genus database with same CATH topology
1S4DA 3T0GA 2CBFA 2PCGA 2QBUA 2PB4A 2EHCA 1WNGA 2ELEA 2OWGA 2PCAA 1VCEA 2ED5A 4MV0A 1CBFA 1VHVA 3KWPA 3NEIA 2ED3A 2PB5A 2BB3A 4N7BA 2DV7A 3KELA 2PCHA 2E17A 2PCKA 1PJTA 2EK4A 3DNFA 2ELDA 3TIXB 3KEFA 1V9AA 2EH2A 2EH5A 2E7RA 2EJJA 4MUYA 2HUTA 2OWKA 3UTDA 2EMUA 2EH4A 2EGLA 3F7TA 3SZUA 2EJKA 2PB6A 2EGSA 2EKAA 4H4DA 1PJSA 2EK3A 2E15A 2E08A 2DV4A 2DSGA 1VA0A 2EK2A 4H4CA 2DV3A 2P6KA 2P6LA 2OWFA 2ZVBA 1WDEA 1VE2A 2EN5A 3KEMA 3UTCA 2EL2A 2YBOA 2OWVA 3HH1A 2EGBA 2NPNA 3KE9A 2DEKA 3ZGLA 2HR8A 3I4TA 2E0KA 3NDCA 3UWMA 2EL3A 3KE8A 2PCIA 2DXVA 2E8RA 1WYZA 2EHLA 2P9DA 3NUTA 2E8SA 2EEQA 3UV7A 2DXWA 2YBQA 2E16A 3UV6A 2EMRA 3ND1A 3UV3A 2E8HA 3ZGNA 2E07A 3LMMA 2E4NA 2P6DA 2HUXA 2E4RA 2DSIA 3FFYA 2EL1A 2OWUA 2P6IA 3FQ6A 2EL0A 4EB3A 3SZLA 2EK7A 5HW4A 2P5FA 4MUXA 2HUQA 2DXXA 2PCMA 3T0FA 2E0NA 2E8QA 2P5CA 4MV5A 2P2XA 3SZOA 2DSHA 2HUVA 2Z6RA 2EJZA 2KYYA 4H4EA 3URKA 2ZVCA 1PJQA 2ENIA 2DV5A 4E16A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1S4D A;  2CBF A;  2PCG A;  2QBU A;  2PB4 A;  2EHC A;  1WNG A;  2ELE A;  2OWG A;  2PCA A;  1VCE A;  2ED5 A;  1CBF A;  1VHV A;  3KWP A;  3NEI A;  2ED3 A;  2PB5 A;  2BB3 A;  2DV7 A;  2PCH A;  2E17 A;  2PCK A;  1PJT A;  2EK4 A;  2ELD A;  1V9A A;  2EH2 A;  2EH5 A;  2E7R A;  2EJJ A;  2HUT A;  2OWK A;  2EMU A;  2EH4 A;  2EGL A;  2EJK A;  2PB6 A;  2EGS A;  2EKA A;  1PJS A;  2EK3 A;  2E15 A;  2E08 A;  2DV4 A;  2DSG A;  1VA0 A;  2EK2 A;  2DV3 A;  2P6K A;  2P6L A;  2OWF A;  2ZVB A;  1WDE A;  1VE2 A;  2EN5 A;  2EL2 A;  2YBO A;  2OWV A;  3HH1 A;  2EGB A;  2NPN A;  2DEK A;  2HR8 A;  3I4T A;  2E0K A;  3NDC A;  2EL3 A;  2PCI A;  2DXV A;  2E8R A;  1WYZ A;  2EHL A;  2P9D A;  3NUT A;  2E8S A;  2EEQ A;  2DXW A;  2YBQ A;  2E16 A;  2EMR A;  3ND1 A;  2E8H A;  2E07 A;  2E4N A;  2P6D A;  2HUX A;  2E4R A;  2DSI A;  3FFY A;  2EL1 A;  2OWU A;  2P6I A;  3FQ6 A;  2EL0 A;  2EK7 A;  5HW4 A;  2P5F A;  2HUQ A;  2DXX A;  2PCM A;  2E0N A;  2E8Q A;  2P5C A;  2P2X A;  2DSH A;  2HUV A;  2Z6R A;  2EJZ A;  2ZVC A;  1PJQ A;  2ENI A;  2DV5 A;  4E16 A; 
#chains in the Genus database with same CATH topology
 1S4D A;  3T0G A;  2CBF A;  2PCG A;  2QBU A;  2PB4 A;  2EHC A;  1WNG A;  2ELE A;  2OWG A;  2PCA A;  1VCE A;  2ED5 A;  4MV0 A;  1CBF A;  1VHV A;  3KWP A;  3NEI A;  2ED3 A;  2PB5 A;  2BB3 A;  4N7B A;  2DV7 A;  3KEL A;  2PCH A;  2E17 A;  2PCK A;  1PJT A;  2EK4 A;  3DNF A;  2ELD A;  3TIX B;  3KEF A;  1V9A A;  2EH2 A;  2EH5 A;  2E7R A;  2EJJ A;  4MUY A;  2HUT A;  2OWK A;  3UTD A;  2EMU A;  2EH4 A;  2EGL A;  3F7T A;  3SZU A;  2EJK A;  2PB6 A;  2EGS A;  2EKA A;  4H4D A;  1PJS A;  2EK3 A;  2E15 A;  2E08 A;  2DV4 A;  2DSG A;  1VA0 A;  2EK2 A;  4H4C A;  2DV3 A;  2P6K A;  2P6L A;  2OWF A;  2ZVB A;  1WDE A;  1VE2 A;  2EN5 A;  3KEM A;  3UTC A;  2EL2 A;  2YBO A;  2OWV A;  3HH1 A;  2EGB A;  2NPN A;  3KE9 A;  2DEK A;  3ZGL A;  2HR8 A;  3I4T A;  2E0K A;  3NDC A;  3UWM A;  2EL3 A;  3KE8 A;  2PCI A;  2DXV A;  2E8R A;  1WYZ A;  2EHL A;  2P9D A;  3NUT A;  2E8S A;  2EEQ A;  3UV7 A;  2DXW A;  2YBQ A;  2E16 A;  3UV6 A;  2EMR A;  3ND1 A;  3UV3 A;  2E8H A;  3ZGN A;  2E07 A;  3LMM A;  2E4N A;  2P6D A;  2HUX A;  2E4R A;  2DSI A;  3FFY A;  2EL1 A;  2OWU A;  2P6I A;  3FQ6 A;  2EL0 A;  4EB3 A;  3SZL A;  2EK7 A;  5HW4 A;  2P5F A;  4MUX A;  2HUQ A;  2DXX A;  2PCM A;  3T0F A;  2E0N A;  2E8Q A;  2P5C A;  4MV5 A;  2P2X A;  3SZO A;  2DSH A;  2HUV A;  2Z6R A;  2EJZ A;  2KYY A;  4H4E A;  3URK A;  2ZVC A;  1PJQ A;  2ENI A;  2DV5 A;  4E16 A; 
#chains in the Genus database with same CATH homology
 1S4D A;  3T0G A;  2CBF A;  2PCG A;  2QBU A;  2PB4 A;  2EHC A;  1WNG A;  2ELE A;  2OWG A;  2PCA A;  1VCE A;  2ED5 A;  4MV0 A;  1CBF A;  1VHV A;  3KWP A;  3NEI A;  2ED3 A;  2PB5 A;  2BB3 A;  4N7B A;  2DV7 A;  3KEL A;  2PCH A;  2E17 A;  2PCK A;  1PJT A;  2EK4 A;  3DNF A;  2ELD A;  3TIX B;  3KEF A;  1V9A A;  2EH2 A;  2EH5 A;  2E7R A;  2EJJ A;  4MUY A;  2HUT A;  2OWK A;  3UTD A;  2EMU A;  2EH4 A;  2EGL A;  3F7T A;  3SZU A;  2EJK A;  2PB6 A;  2EGS A;  2EKA A;  4H4D A;  1PJS A;  2EK3 A;  2E15 A;  2E08 A;  2DV4 A;  2DSG A;  1VA0 A;  2EK2 A;  4H4C A;  2DV3 A;  2P6K A;  2P6L A;  2OWF A;  2ZVB A;  1WDE A;  1VE2 A;  2EN5 A;  3KEM A;  3UTC A;  2EL2 A;  2YBO A;  2OWV A;  3HH1 A;  2EGB A;  2NPN A;  3KE9 A;  2DEK A;  3ZGL A;  2HR8 A;  3I4T A;  2E0K A;  3NDC A;  3UWM A;  2EL3 A;  3KE8 A;  2PCI A;  2DXV A;  2E8R A;  1WYZ A;  2EHL A;  2P9D A;  3NUT A;  2E8S A;  2EEQ A;  3UV7 A;  2DXW A;  2YBQ A;  2E16 A;  3UV6 A;  2EMR A;  3ND1 A;  3UV3 A;  2E8H A;  3ZGN A;  2E07 A;  3LMM A;  2E4N A;  2P6D A;  2HUX A;  2E4R A;  2DSI A;  3FFY A;  2EL1 A;  2OWU A;  2P6I A;  3FQ6 A;  2EL0 A;  4EB3 A;  3SZL A;  2EK7 A;  5HW4 A;  2P5F A;  4MUX A;  2HUQ A;  2DXX A;  2PCM A;  3T0F A;  2E0N A;  2E8Q A;  2P5C A;  4MV5 A;  2P2X A;  3SZO A;  2DSH A;  2HUV A;  2Z6R A;  2EJZ A;  2KYY A;  4H4E A;  3URK A;  2ZVC A;  1PJQ A;  2ENI A;  2DV5 A;  4E16 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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