2E7RA

Crystal structure of glu54 to arg mutant of diphthine synthase
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
b'MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKRIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords diphthine synthase
publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2007-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2e7rA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2e7rA01
2ZVBA 2P5CA 2OWKA 2E7RA 2EJKA 2PB5A 2PCMA 2OWVA 2EK2A 2EK4A 2ED5A 2ZVCA 3NDCA 2EL0A 2ELEA 2PCIA 2E17A 2EHLA 1PJQA 2E16A 2EH2A 2HUQA 3NUTA 1WYZA 1VCEA 1V9AA 2EMRA 3NEIA 3FQ6A 2OWUA 2DV7A 2E8SA 2EK3A 2HR8A 2YBQA 2EL2A 2PB6A 2EK7A 2P5FA 2ELDA 2HUTA 2EH4A 2P9DA 1PJTA 2P6IA 1WNGA 2DV5A 2PCKA 2E8RA 2DXVA 2EGLA 2EH5A 2EMUA 3KWPA 2P2XA 2E0KA 2E0NA 2P6DA 2EKAA 2EEQA 2EJZA 2HUVA 2PCGA 1VE2A 2EGBA 1WDEA 2EJJA 2E4RA 2E4NA 1VA0A 2PCHA 2E08A 2DSHA 2DXWA 2NPNA 2P6LA 2OWFA 2EN5A 1VHVA 2ENIA 2DSIA 2OWGA 2DV3A 2PB4A 3I4TA 2EL3A 3ND1A 4E16A 2DEKA 2EGSA 2BB3A 2DV4A 3HH1A 1S4DA 2E8QA 3FFYA 2ED3A 2DSGA 2PCAA 2DXXA 2CBFA 1CBFA 2EL1A 2EHCA 2E15A 1PJSA 2E8HA 2P6KA 2E07A 5HW4A 2QBUA 2YBOA 2Z6RA 2HUXA
chains in the Genus database with same CATH superfamily
2ZVBA 2P5CA 2OWKA 2E7RA 2EJKA 2PB5A 2PCMA 2OWVA 4MV0A 2EK2A 2EK4A 3KEMA 2ED5A 2ZVCA 3NDCA 4MV5A 2EL0A 2ELEA 2PCIA 2E17A 2EHLA 3SZOA 1PJQA 2E16A 2EH2A 2HUQA 3NUTA 1WYZA 4H4DA 1VCEA 1V9AA 2EMRA 3NEIA 3FQ6A 2OWUA 4MUXA 2DV7A 2E8SA 2EK3A 3URKA 4MUYA 3KEFA 2HR8A 2YBQA 2EL2A 4EB3A 3KE8A 2PB6A 2EK7A 2P5FA 2ELDA 3F7TA 2HUTA 2EH4A 2P9DA 1PJTA 2P6IA 1WNGA 2DV5A 2PCKA 2E8RA 2DXVA 2EGLA 2EH5A 2EMUA 3UWMA 3KWPA 3ZGLA 4N7BA 2P2XA 2E0KA 2E0NA 2P6DA 2EKAA 2EEQA 3UV6A 2EJZA 2HUVA 2PCGA 1VE2A 3SZUA 3UV3A 2EGBA 1WDEA 2EJJA 2E4RA 2E4NA 1VA0A 2PCHA 2E08A 2DSHA 2DXWA 2NPNA 2P6LA 3SZLA 3DNFA 2OWFA 2EN5A 3T0FA 3T0GA 1VHVA 2ENIA 2DSIA 3UTDA 4H4CA 2OWGA 3UTCA 2DV3A 2PB4A 3I4TA 2EL3A 3LMMA 3ND1A 4E16A 2DEKA 2EGSA 2BB3A 2DV4A 3HH1A 1S4DA 3KELA 2E8QA 3FFYA 2ED3A 2DSGA 2PCAA 2DXXA 2CBFA 1CBFA 2EL1A 2EHCA 3ZGNA 2E15A 2KYYA 4H4EA 1PJSA 2E8HA 2P6KA 2E07A 5HW4A 3KE9A 2QBUA 3TIXB 2YBOA 2Z6RA 3UV7A 2HUXA
chains in the Genus database with same CATH topology
2ZVBA 2P5CA 2OWKA 2E7RA 2EJKA 2PB5A 2PCMA 2OWVA 4MV0A 2EK2A 2EK4A 3KEMA 2ED5A 2ZVCA 3NDCA 4MV5A 2EL0A 2ELEA 2PCIA 2E17A 2EHLA 3SZOA 1PJQA 2E16A 2EH2A 2HUQA 3NUTA 1WYZA 4H4DA 1VCEA 1V9AA 2EMRA 3NEIA 3FQ6A 2OWUA 4MUXA 2DV7A 2E8SA 2EK3A 3URKA 4MUYA 3KEFA 2HR8A 2YBQA 2EL2A 4EB3A 3KE8A 2PB6A 2EK7A 2P5FA 2ELDA 3F7TA 2HUTA 2EH4A 2P9DA 1PJTA 2P6IA 1WNGA 2DV5A 2PCKA 2E8RA 2DXVA 2EGLA 2EH5A 2EMUA 3UWMA 3KWPA 3ZGLA 4N7BA 2P2XA 2E0KA 2E0NA 2P6DA 2EKAA 2EEQA 3UV6A 2EJZA 2HUVA 2PCGA 1VE2A 3SZUA 3UV3A 2EGBA 1WDEA 2EJJA 2E4RA 2E4NA 1VA0A 2PCHA 2E08A 2DSHA 2DXWA 2NPNA 2P6LA 3SZLA 3DNFA 2OWFA 2EN5A 3T0FA 3T0GA 1VHVA 2ENIA 2DSIA 3UTDA 4H4CA 2OWGA 3UTCA 2DV3A 2PB4A 3I4TA 2EL3A 3LMMA 3ND1A 4E16A 2DEKA 2EGSA 2BB3A 2DV4A 3HH1A 1S4DA 3KELA 2E8QA 3FFYA 2ED3A 2DSGA 2PCAA 2DXXA 2CBFA 1CBFA 2EL1A 2EHCA 3ZGNA 2E15A 2KYYA 4H4EA 1PJSA 2E8HA 2P6KA 2E07A 5HW4A 3KE9A 2QBUA 3TIXB 2YBOA 2Z6RA 3UV7A 2HUXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZVB A;  2P5C A;  2OWK A;  2E7R A;  2EJK A;  2PB5 A;  2PCM A;  2OWV A;  2EK2 A;  2EK4 A;  2ED5 A;  2ZVC A;  3NDC A;  2EL0 A;  2ELE A;  2PCI A;  2E17 A;  2EHL A;  1PJQ A;  2E16 A;  2EH2 A;  2HUQ A;  3NUT A;  1WYZ A;  1VCE A;  1V9A A;  2EMR A;  3NEI A;  3FQ6 A;  2OWU A;  2DV7 A;  2E8S A;  2EK3 A;  2HR8 A;  2YBQ A;  2EL2 A;  2PB6 A;  2EK7 A;  2P5F A;  2ELD A;  2HUT A;  2EH4 A;  2P9D A;  1PJT A;  2P6I A;  1WNG A;  2DV5 A;  2PCK A;  2E8R A;  2DXV A;  2EGL A;  2EH5 A;  2EMU A;  3KWP A;  2P2X A;  2E0K A;  2E0N A;  2P6D A;  2EKA A;  2EEQ A;  2EJZ A;  2HUV A;  2PCG A;  1VE2 A;  2EGB A;  1WDE A;  2EJJ A;  2E4R A;  2E4N A;  1VA0 A;  2PCH A;  2E08 A;  2DSH A;  2DXW A;  2NPN A;  2P6L A;  2OWF A;  2EN5 A;  1VHV A;  2ENI A;  2DSI A;  2OWG A;  2DV3 A;  2PB4 A;  3I4T A;  2EL3 A;  3ND1 A;  4E16 A;  2DEK A;  2EGS A;  2BB3 A;  2DV4 A;  3HH1 A;  1S4D A;  2E8Q A;  3FFY A;  2ED3 A;  2DSG A;  2PCA A;  2DXX A;  2CBF A;  1CBF A;  2EL1 A;  2EHC A;  2E15 A;  1PJS A;  2E8H A;  2P6K A;  2E07 A;  5HW4 A;  2QBU A;  2YBO A;  2Z6R A;  2HUX A; 
#chains in the Genus database with same CATH topology
 2ZVB A;  2P5C A;  2OWK A;  2E7R A;  2EJK A;  2PB5 A;  2PCM A;  2OWV A;  4MV0 A;  2EK2 A;  2EK4 A;  3KEM A;  2ED5 A;  2ZVC A;  3NDC A;  4MV5 A;  2EL0 A;  2ELE A;  2PCI A;  2E17 A;  2EHL A;  3SZO A;  1PJQ A;  2E16 A;  2EH2 A;  2HUQ A;  3NUT A;  1WYZ A;  4H4D A;  1VCE A;  1V9A A;  2EMR A;  3NEI A;  3FQ6 A;  2OWU A;  4MUX A;  2DV7 A;  2E8S A;  2EK3 A;  3URK A;  4MUY A;  3KEF A;  2HR8 A;  2YBQ A;  2EL2 A;  4EB3 A;  3KE8 A;  2PB6 A;  2EK7 A;  2P5F A;  2ELD A;  3F7T A;  2HUT A;  2EH4 A;  2P9D A;  1PJT A;  2P6I A;  1WNG A;  2DV5 A;  2PCK A;  2E8R A;  2DXV A;  2EGL A;  2EH5 A;  2EMU A;  3UWM A;  3KWP A;  3ZGL A;  4N7B A;  2P2X A;  2E0K A;  2E0N A;  2P6D A;  2EKA A;  2EEQ A;  3UV6 A;  2EJZ A;  2HUV A;  2PCG A;  1VE2 A;  3SZU A;  3UV3 A;  2EGB A;  1WDE A;  2EJJ A;  2E4R A;  2E4N A;  1VA0 A;  2PCH A;  2E08 A;  2DSH A;  2DXW A;  2NPN A;  2P6L A;  3SZL A;  3DNF A;  2OWF A;  2EN5 A;  3T0F A;  3T0G A;  1VHV A;  2ENI A;  2DSI A;  3UTD A;  4H4C A;  2OWG A;  3UTC A;  2DV3 A;  2PB4 A;  3I4T A;  2EL3 A;  3LMM A;  3ND1 A;  4E16 A;  2DEK A;  2EGS A;  2BB3 A;  2DV4 A;  3HH1 A;  1S4D A;  3KEL A;  2E8Q A;  3FFY A;  2ED3 A;  2DSG A;  2PCA A;  2DXX A;  2CBF A;  1CBF A;  2EL1 A;  2EHC A;  3ZGN A;  2E15 A;  2KYY A;  4H4E A;  1PJS A;  2E8H A;  2P6K A;  2E07 A;  5HW4 A;  3KE9 A;  2QBU A;  3TIX B;  2YBO A;  2Z6R A;  3UV7 A;  2HUX A; 
#chains in the Genus database with same CATH homology
 2ZVB A;  2P5C A;  2OWK A;  2E7R A;  2EJK A;  2PB5 A;  2PCM A;  2OWV A;  4MV0 A;  2EK2 A;  2EK4 A;  3KEM A;  2ED5 A;  2ZVC A;  3NDC A;  4MV5 A;  2EL0 A;  2ELE A;  2PCI A;  2E17 A;  2EHL A;  3SZO A;  1PJQ A;  2E16 A;  2EH2 A;  2HUQ A;  3NUT A;  1WYZ A;  4H4D A;  1VCE A;  1V9A A;  2EMR A;  3NEI A;  3FQ6 A;  2OWU A;  4MUX A;  2DV7 A;  2E8S A;  2EK3 A;  3URK A;  4MUY A;  3KEF A;  2HR8 A;  2YBQ A;  2EL2 A;  4EB3 A;  3KE8 A;  2PB6 A;  2EK7 A;  2P5F A;  2ELD A;  3F7T A;  2HUT A;  2EH4 A;  2P9D A;  1PJT A;  2P6I A;  1WNG A;  2DV5 A;  2PCK A;  2E8R A;  2DXV A;  2EGL A;  2EH5 A;  2EMU A;  3UWM A;  3KWP A;  3ZGL A;  4N7B A;  2P2X A;  2E0K A;  2E0N A;  2P6D A;  2EKA A;  2EEQ A;  3UV6 A;  2EJZ A;  2HUV A;  2PCG A;  1VE2 A;  3SZU A;  3UV3 A;  2EGB A;  1WDE A;  2EJJ A;  2E4R A;  2E4N A;  1VA0 A;  2PCH A;  2E08 A;  2DSH A;  2DXW A;  2NPN A;  2P6L A;  3SZL A;  3DNF A;  2OWF A;  2EN5 A;  3T0F A;  3T0G A;  1VHV A;  2ENI A;  2DSI A;  3UTD A;  4H4C A;  2OWG A;  3UTC A;  2DV3 A;  2PB4 A;  3I4T A;  2EL3 A;  3LMM A;  3ND1 A;  4E16 A;  2DEK A;  2EGS A;  2BB3 A;  2DV4 A;  3HH1 A;  1S4D A;  3KEL A;  2E8Q A;  3FFY A;  2ED3 A;  2DSG A;  2PCA A;  2DXX A;  2CBF A;  1CBF A;  2EL1 A;  2EHC A;  3ZGN A;  2E15 A;  2KYY A;  4H4E A;  1PJS A;  2E8H A;  2P6K A;  2E07 A;  5HW4 A;  3KE9 A;  2QBU A;  3TIX B;  2YBO A;  2Z6R A;  3UV7 A;  2HUX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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