2E7RA

Crystal structure of glu54 to arg mutant of diphthine synthase
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKRIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2007-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2e7rA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2e7rA01
2EL1A 3FFYA 2E8SA 3FQ6A 1VCEA 2EH4A 2ELDA 2EK4A 2E8RA 2E0KA 2EHLA 2QBUA 2E16A 2EJZA 2DSHA 3NUTA 4E16A 2NPNA 2PCHA 2PB6A 2ELEA 1PJSA 2EJJA 3NDCA 2DSIA 5HW4A 2E15A 2EL2A 2P2XA 1CBFA 2EMRA 2OWVA 2OWGA 2DV5A 1PJQA 2EK2A 2E4RA 2EGLA 2EMUA 1VA0A 2ZVCA 2OWUA 3I4TA 1PJTA 2EH2A 3HH1A 2P5CA 1VHVA 2E8QA 2OWFA 2DV3A 2OWKA 2EL3A 2E0NA 2E08A 2P5FA 2PCMA 2Z6RA 2EL0A 1V9AA 1VE2A 2P6KA 1WYZA 2HR8A 2YBOA 2PCGA 2DXWA 3ND1A 2PCKA 2E8HA 2DV4A 2PB5A 2EH5A 2EEQA 2YBQA 2DV7A 2P6IA 2P6LA 1WDEA 2ED5A 2HUXA 2HUQA 2EGBA 2E07A 2EGSA 2DXXA 3NEIA 2EK3A 1WNGA 2PCAA 2E17A 2EKAA 2E7RA 2ENIA 2ZVBA 3KWPA 2HUVA 2BB3A 2DEKA 2P9DA 2P6DA 2ED3A 2PCIA 2EJKA 2EN5A 1S4DA 2HUTA 2PB4A 2E4NA 2EK7A 2CBFA 2EHCA 2DSGA 2DXVA
chains in the Genus database with same CATH superfamily
2EL1A 3FFYA 2E8SA 3TIXB 3FQ6A 1VCEA 2EH4A 3UTDA 2ELDA 2EK4A 2E8RA 2E0KA 2EHLA 2QBUA 2E16A 2EJZA 2DSHA 3KE9A 3T0GA 3NUTA 4E16A 2NPNA 2PCHA 2PB6A 2ELEA 1PJSA 2EJJA 3NDCA 2DSIA 5HW4A 4N7BA 2E15A 3ZGNA 2EL2A 2P2XA 1CBFA 2EMRA 3DNFA 2OWVA 2OWGA 2DV5A 4H4CA 4MV0A 3KEMA 1PJQA 2EK2A 2E4RA 3UV6A 2EGLA 2EMUA 1VA0A 3UV7A 2ZVCA 3KE8A 3LMMA 2OWUA 3I4TA 1PJTA 2EH2A 3HH1A 4MUYA 2P5CA 1VHVA 2E8QA 2OWFA 3SZOA 2DV3A 3KEFA 2OWKA 4MUXA 2EL3A 2E0NA 2E08A 2P5FA 2PCMA 2Z6RA 2EL0A 1V9AA 1VE2A 3F7TA 2P6KA 1WYZA 2HR8A 4H4DA 2YBOA 3UTCA 2PCGA 2DXWA 2KYYA 3ND1A 2PCKA 2E8HA 2DV4A 2PB5A 2EH5A 3ZGLA 2EEQA 2YBQA 2DV7A 2P6IA 2P6LA 1WDEA 2ED5A 2HUXA 2HUQA 3UV3A 4H4EA 2EGBA 2E07A 2EGSA 2DXXA 3NEIA 2EK3A 1WNGA 2PCAA 3SZUA 2E17A 2EKAA 2E7RA 2ENIA 2ZVBA 3KWPA 2HUVA 3URKA 2BB3A 4MV5A 3SZLA 2DEKA 4EB3A 2P9DA 2P6DA 3T0FA 3KELA 2ED3A 2PCIA 2EJKA 2EN5A 1S4DA 2HUTA 3UWMA 2PB4A 2E4NA 2EK7A 2CBFA 2EHCA 2DSGA 2DXVA
chains in the Genus database with same CATH topology
2EL1A 3FFYA 2E8SA 3TIXB 3FQ6A 1VCEA 2EH4A 3UTDA 2ELDA 2EK4A 2E8RA 2E0KA 2EHLA 2QBUA 2E16A 2EJZA 2DSHA 3KE9A 3T0GA 3NUTA 4E16A 2NPNA 2PCHA 2PB6A 2ELEA 1PJSA 2EJJA 3NDCA 2DSIA 5HW4A 4N7BA 2E15A 3ZGNA 2EL2A 2P2XA 1CBFA 2EMRA 3DNFA 2OWVA 2OWGA 2DV5A 4H4CA 4MV0A 3KEMA 1PJQA 2EK2A 2E4RA 3UV6A 2EGLA 2EMUA 1VA0A 3UV7A 2ZVCA 3KE8A 3LMMA 2OWUA 3I4TA 1PJTA 2EH2A 3HH1A 4MUYA 2P5CA 1VHVA 2E8QA 2OWFA 3SZOA 2DV3A 3KEFA 2OWKA 4MUXA 2EL3A 2E0NA 2E08A 2P5FA 2PCMA 2Z6RA 2EL0A 1V9AA 1VE2A 3F7TA 2P6KA 1WYZA 2HR8A 4H4DA 2YBOA 3UTCA 2PCGA 2DXWA 2KYYA 3ND1A 2PCKA 2E8HA 2DV4A 2PB5A 2EH5A 3ZGLA 2EEQA 2YBQA 2DV7A 2P6IA 2P6LA 1WDEA 2ED5A 2HUXA 2HUQA 3UV3A 4H4EA 2EGBA 2E07A 2EGSA 2DXXA 3NEIA 2EK3A 1WNGA 2PCAA 3SZUA 2E17A 2EKAA 2E7RA 2ENIA 2ZVBA 3KWPA 2HUVA 3URKA 2BB3A 4MV5A 3SZLA 2DEKA 4EB3A 2P9DA 2P6DA 3T0FA 3KELA 2ED3A 2PCIA 2EJKA 2EN5A 1S4DA 2HUTA 3UWMA 2PB4A 2E4NA 2EK7A 2CBFA 2EHCA 2DSGA 2DXVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EL1 A;  3FFY A;  2E8S A;  3FQ6 A;  1VCE A;  2EH4 A;  2ELD A;  2EK4 A;  2E8R A;  2E0K A;  2EHL A;  2QBU A;  2E16 A;  2EJZ A;  2DSH A;  3NUT A;  4E16 A;  2NPN A;  2PCH A;  2PB6 A;  2ELE A;  1PJS A;  2EJJ A;  3NDC A;  2DSI A;  5HW4 A;  2E15 A;  2EL2 A;  2P2X A;  1CBF A;  2EMR A;  2OWV A;  2OWG A;  2DV5 A;  1PJQ A;  2EK2 A;  2E4R A;  2EGL A;  2EMU A;  1VA0 A;  2ZVC A;  2OWU A;  3I4T A;  1PJT A;  2EH2 A;  3HH1 A;  2P5C A;  1VHV A;  2E8Q A;  2OWF A;  2DV3 A;  2OWK A;  2EL3 A;  2E0N A;  2E08 A;  2P5F A;  2PCM A;  2Z6R A;  2EL0 A;  1V9A A;  1VE2 A;  2P6K A;  1WYZ A;  2HR8 A;  2YBO A;  2PCG A;  2DXW A;  3ND1 A;  2PCK A;  2E8H A;  2DV4 A;  2PB5 A;  2EH5 A;  2EEQ A;  2YBQ A;  2DV7 A;  2P6I A;  2P6L A;  1WDE A;  2ED5 A;  2HUX A;  2HUQ A;  2EGB A;  2E07 A;  2EGS A;  2DXX A;  3NEI A;  2EK3 A;  1WNG A;  2PCA A;  2E17 A;  2EKA A;  2E7R A;  2ENI A;  2ZVB A;  3KWP A;  2HUV A;  2BB3 A;  2DEK A;  2P9D A;  2P6D A;  2ED3 A;  2PCI A;  2EJK A;  2EN5 A;  1S4D A;  2HUT A;  2PB4 A;  2E4N A;  2EK7 A;  2CBF A;  2EHC A;  2DSG A;  2DXV A; 
#chains in the Genus database with same CATH topology
 2EL1 A;  3FFY A;  2E8S A;  3TIX B;  3FQ6 A;  1VCE A;  2EH4 A;  3UTD A;  2ELD A;  2EK4 A;  2E8R A;  2E0K A;  2EHL A;  2QBU A;  2E16 A;  2EJZ A;  2DSH A;  3KE9 A;  3T0G A;  3NUT A;  4E16 A;  2NPN A;  2PCH A;  2PB6 A;  2ELE A;  1PJS A;  2EJJ A;  3NDC A;  2DSI A;  5HW4 A;  4N7B A;  2E15 A;  3ZGN A;  2EL2 A;  2P2X A;  1CBF A;  2EMR A;  3DNF A;  2OWV A;  2OWG A;  2DV5 A;  4H4C A;  4MV0 A;  3KEM A;  1PJQ A;  2EK2 A;  2E4R A;  3UV6 A;  2EGL A;  2EMU A;  1VA0 A;  3UV7 A;  2ZVC A;  3KE8 A;  3LMM A;  2OWU A;  3I4T A;  1PJT A;  2EH2 A;  3HH1 A;  4MUY A;  2P5C A;  1VHV A;  2E8Q A;  2OWF A;  3SZO A;  2DV3 A;  3KEF A;  2OWK A;  4MUX A;  2EL3 A;  2E0N A;  2E08 A;  2P5F A;  2PCM A;  2Z6R A;  2EL0 A;  1V9A A;  1VE2 A;  3F7T A;  2P6K A;  1WYZ A;  2HR8 A;  4H4D A;  2YBO A;  3UTC A;  2PCG A;  2DXW A;  2KYY A;  3ND1 A;  2PCK A;  2E8H A;  2DV4 A;  2PB5 A;  2EH5 A;  3ZGL A;  2EEQ A;  2YBQ A;  2DV7 A;  2P6I A;  2P6L A;  1WDE A;  2ED5 A;  2HUX A;  2HUQ A;  3UV3 A;  4H4E A;  2EGB A;  2E07 A;  2EGS A;  2DXX A;  3NEI A;  2EK3 A;  1WNG A;  2PCA A;  3SZU A;  2E17 A;  2EKA A;  2E7R A;  2ENI A;  2ZVB A;  3KWP A;  2HUV A;  3URK A;  2BB3 A;  4MV5 A;  3SZL A;  2DEK A;  4EB3 A;  2P9D A;  2P6D A;  3T0F A;  3KEL A;  2ED3 A;  2PCI A;  2EJK A;  2EN5 A;  1S4D A;  2HUT A;  3UWM A;  2PB4 A;  2E4N A;  2EK7 A;  2CBF A;  2EHC A;  2DSG A;  2DXV A; 
#chains in the Genus database with same CATH homology
 2EL1 A;  3FFY A;  2E8S A;  3TIX B;  3FQ6 A;  1VCE A;  2EH4 A;  3UTD A;  2ELD A;  2EK4 A;  2E8R A;  2E0K A;  2EHL A;  2QBU A;  2E16 A;  2EJZ A;  2DSH A;  3KE9 A;  3T0G A;  3NUT A;  4E16 A;  2NPN A;  2PCH A;  2PB6 A;  2ELE A;  1PJS A;  2EJJ A;  3NDC A;  2DSI A;  5HW4 A;  4N7B A;  2E15 A;  3ZGN A;  2EL2 A;  2P2X A;  1CBF A;  2EMR A;  3DNF A;  2OWV A;  2OWG A;  2DV5 A;  4H4C A;  4MV0 A;  3KEM A;  1PJQ A;  2EK2 A;  2E4R A;  3UV6 A;  2EGL A;  2EMU A;  1VA0 A;  3UV7 A;  2ZVC A;  3KE8 A;  3LMM A;  2OWU A;  3I4T A;  1PJT A;  2EH2 A;  3HH1 A;  4MUY A;  2P5C A;  1VHV A;  2E8Q A;  2OWF A;  3SZO A;  2DV3 A;  3KEF A;  2OWK A;  4MUX A;  2EL3 A;  2E0N A;  2E08 A;  2P5F A;  2PCM A;  2Z6R A;  2EL0 A;  1V9A A;  1VE2 A;  3F7T A;  2P6K A;  1WYZ A;  2HR8 A;  4H4D A;  2YBO A;  3UTC A;  2PCG A;  2DXW A;  2KYY A;  3ND1 A;  2PCK A;  2E8H A;  2DV4 A;  2PB5 A;  2EH5 A;  3ZGL A;  2EEQ A;  2YBQ A;  2DV7 A;  2P6I A;  2P6L A;  1WDE A;  2ED5 A;  2HUX A;  2HUQ A;  3UV3 A;  4H4E A;  2EGB A;  2E07 A;  2EGS A;  2DXX A;  3NEI A;  2EK3 A;  1WNG A;  2PCA A;  3SZU A;  2E17 A;  2EKA A;  2E7R A;  2ENI A;  2ZVB A;  3KWP A;  2HUV A;  3URK A;  2BB3 A;  4MV5 A;  3SZL A;  2DEK A;  4EB3 A;  2P9D A;  2P6D A;  3T0F A;  3KEL A;  2ED3 A;  2PCI A;  2EJK A;  2EN5 A;  1S4D A;  2HUT A;  3UWM A;  2PB4 A;  2E4N A;  2EK7 A;  2CBF A;  2EHC A;  2DSG A;  2DXV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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