2EBZA

Solution structure of the rgs domain from human regulator of g-protein signaling 12 (rgs12)
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
155
structure length
155
Chain Sequence
GSSGSSGRERRVASWAVSFERLLQDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATTPVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRALPDSQQVPSSPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Regulator of G-protein signaling 12
publication title Solution structure of the RGS domain from human Regulator of G-protein signaling 12 (RGS12)
rcsb
source organism Homo sapiens
total genus 33
structure length 155
sequence length 155
ec nomenclature
pdb deposition date 2007-02-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2ebzA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2ebzA01
1EZYA 2IHDA 3NYNA 3C7KB 1CMZA 3V5WA 2BT2A 2OWIA 1DK8A 1OMWA 2OJ4A 2DLVA 2BV1A 2CRPA 4TNDA 3C7LA 2JNUA 5HE2A 1AGRE 2IK8B 3KRXA 4MK0A 2D9JA 5HE1A 1FQKB 4PNKA 4EKDB 2V4ZB 2BCJA 1FQJB 3PSCA 2GTPC 1FQIA 3KRWA 3UZTA 2AF0A 1EMUA 4TNBA 2EBZA 2JM5A 1EZTA 3NYOA 5DO9B 5HE0A 2ODEB 3CIKA 3PVWA 5HE3A 2IHBB 3PVUA
chains in the Genus database with same CATH superfamily
3I5QA 1EZYA 2IHDA 3NYNA 3C7KB 1CMZA 3V5WA 2BT2A 2OWIA 1DK8A 1OMWA 2OJ4A 2DLVA 2BV1A 2CRPA 4TNDA 3C7LA 2JNUA 5HE2A 1AGRE 2IK8B 3KRXA 4MK0A 2D9JA 5HE1A 1FQKB 4PNKA 4EKDB 2V4ZB 2BCJA 4HTEA 1FQJB 3PSCA 2GTPC 1FQIA 3KRWA 3UZTA 2AF0A 1EMUA 4TNBA 2EBZA 2JM5A 5REQB 1EZTA 3NYOA 5DO9B 5HE0A 2ODEB 3CIKA 3PVWA 5HE3A 2IHBB 3QYFA 3PVUA
chains in the Genus database with same CATH topology
1EZYA 2IHDA 3NYNA 3C7KB 1CMZA 3V5WA 2BT2A 2OWIA 1DK8A 1OMWA 2OJ4A 2DLVA 2BV1A 2CRPA 4TNDA 3C7LA 2JNUA 5HE2A 1AGRE 2IK8B 3KRXA 4MK0A 2D9JA 5HE1A 1FQKB 4PNKA 4EKDB 2V4ZB 2BCJA 1FQJB 3PSCA 2GTPC 1FQIA 3KRWA 3UZTA 2AF0A 1EMUA 4TNBA 2EBZA 2JM5A 5REQB 1EZTA 3NYOA 5DO9B 5HE0A 2ODEB 3CIKA 3PVWA 5HE3A 2IHBB 3QYFA 3PVUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EZY A;  2IHD A;  3NYN A;  3C7K B;  1CMZ A;  3V5W A;  2BT2 A;  2OWI A;  1DK8 A;  1OMW A;  2OJ4 A;  2DLV A;  2BV1 A;  2CRP A;  4TND A;  3C7L A;  2JNU A;  5HE2 A;  1AGR E;  2IK8 B;  3KRX A;  4MK0 A;  2D9J A;  5HE1 A;  1FQK B;  4PNK A;  4EKD B;  2V4Z B;  2BCJ A;  1FQJ B;  3PSC A;  2GTP C;  1FQI A;  3KRW A;  3UZT A;  2AF0 A;  1EMU A;  4TNB A;  2EBZ A;  2JM5 A;  1EZT A;  3NYO A;  5DO9 B;  5HE0 A;  2ODE B;  3CIK A;  3PVW A;  5HE3 A;  2IHB B;  3PVU A; 
#chains in the Genus database with same CATH topology
 3I5Q A;  1EZY A;  2IHD A;  3NYN A;  3C7K B;  1CMZ A;  3V5W A;  2BT2 A;  2OWI A;  1DK8 A;  1OMW A;  2OJ4 A;  2DLV A;  2BV1 A;  2CRP A;  4TND A;  3C7L A;  2JNU A;  5HE2 A;  1AGR E;  2IK8 B;  3KRX A;  4MK0 A;  2D9J A;  5HE1 A;  1FQK B;  4PNK A;  4EKD B;  2V4Z B;  2BCJ A;  4HTE A;  1FQJ B;  3PSC A;  2GTP C;  1FQI A;  3KRW A;  3UZT A;  2AF0 A;  1EMU A;  4TNB A;  2EBZ A;  2JM5 A;  5REQ B;  1EZT A;  3NYO A;  5DO9 B;  5HE0 A;  2ODE B;  3CIK A;  3PVW A;  5HE3 A;  2IHB B;  3QYF A;  3PVU A; 
#chains in the Genus database with same CATH homology
 1EZY A;  2IHD A;  3NYN A;  3C7K B;  1CMZ A;  3V5W A;  2BT2 A;  2OWI A;  1DK8 A;  1OMW A;  2OJ4 A;  2DLV A;  2BV1 A;  2CRP A;  4TND A;  3C7L A;  2JNU A;  5HE2 A;  1AGR E;  2IK8 B;  3KRX A;  4MK0 A;  2D9J A;  5HE1 A;  1FQK B;  4PNK A;  4EKD B;  2V4Z B;  2BCJ A;  1FQJ B;  3PSC A;  2GTP C;  1FQI A;  3KRW A;  3UZT A;  2AF0 A;  1EMU A;  4TNB A;  2EBZ A;  2JM5 A;  5REQ B;  1EZT A;  3NYO A;  5DO9 B;  5HE0 A;  2ODE B;  3CIK A;  3PVW A;  5HE3 A;  2IHB B;  3QYF A;  3PVU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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