2EBZA

Solution structure of the rgs domain from human regulator of g-protein signaling 12 (rgs12)
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
155
structure length
155
Chain Sequence
GSSGSSGRERRVASWAVSFERLLQDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATTPVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRALPDSQQVPSSPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the RGS domain from human Regulator of G-protein signaling 12 (RGS12)
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Regulator of G-protein signaling 12
total genus 33
structure length 155
sequence length 155
ec nomenclature
pdb deposition date 2007-02-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2ebzA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2ebzA01
3KRXA 2AF0A 2EBZA 4TNBA 1FQKB 3V5WA 2OJ4A 2IK8B 1DK8A 3PVUA 2JM5A 3PVWA 5HE0A 3NYOA 2V4ZB 3UZTA 1AGRE 3PSCA 3C7LA 2DLVA 2IHDA 5HE2A 1EZYA 3NYNA 2ODEB 5HE3A 1FQJB 4TNDA 2BV1A 2BCJA 3C7KB 2IHBB 1CMZA 1FQIA 2GTPC 2JNUA 2CRPA 2OWIA 3KRWA 1OMWA 5HE1A 4EKDB 1EZTA 2BT2A 5DO9B 3CIKA 4PNKA 4MK0A 1EMUA 2D9JA
chains in the Genus database with same CATH superfamily
3KRXA 2AF0A 2EBZA 4TNBA 1FQKB 3V5WA 2OJ4A 2IK8B 1DK8A 3PVUA 2JM5A 3PVWA 5HE0A 3NYOA 2V4ZB 3UZTA 3I5QA 1AGRE 3PSCA 3C7LA 2DLVA 2IHDA 5HE2A 1EZYA 3NYNA 2ODEB 5HE3A 1FQJB 4TNDA 2BV1A 2BCJA 4HTEA 3C7KB 2IHBB 1CMZA 1FQIA 2GTPC 2JNUA 2CRPA 2OWIA 3KRWA 1OMWA 5HE1A 4EKDB 1EZTA 2BT2A 5DO9B 5REQB 3CIKA 4PNKA 3QYFA 4MK0A 1EMUA 2D9JA
chains in the Genus database with same CATH topology
3KRXA 2AF0A 2EBZA 4TNBA 1FQKB 3V5WA 2OJ4A 2IK8B 1DK8A 3PVUA 2JM5A 3PVWA 5HE0A 3NYOA 2V4ZB 3UZTA 1AGRE 3PSCA 3C7LA 2DLVA 2IHDA 5HE2A 1EZYA 3NYNA 2ODEB 5HE3A 1FQJB 4TNDA 2BV1A 2BCJA 3C7KB 2IHBB 1CMZA 1FQIA 2GTPC 2JNUA 2CRPA 2OWIA 3KRWA 1OMWA 5HE1A 4EKDB 1EZTA 2BT2A 5DO9B 5REQB 3CIKA 4PNKA 3QYFA 4MK0A 1EMUA 2D9JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KRX A;  2AF0 A;  2EBZ A;  4TNB A;  1FQK B;  3V5W A;  2OJ4 A;  2IK8 B;  1DK8 A;  3PVU A;  2JM5 A;  3PVW A;  5HE0 A;  3NYO A;  2V4Z B;  3UZT A;  1AGR E;  3PSC A;  3C7L A;  2DLV A;  2IHD A;  5HE2 A;  1EZY A;  3NYN A;  2ODE B;  5HE3 A;  1FQJ B;  4TND A;  2BV1 A;  2BCJ A;  3C7K B;  2IHB B;  1CMZ A;  1FQI A;  2GTP C;  2JNU A;  2CRP A;  2OWI A;  3KRW A;  1OMW A;  5HE1 A;  4EKD B;  1EZT A;  2BT2 A;  5DO9 B;  3CIK A;  4PNK A;  4MK0 A;  1EMU A;  2D9J A; 
#chains in the Genus database with same CATH topology
 3KRX A;  2AF0 A;  2EBZ A;  4TNB A;  1FQK B;  3V5W A;  2OJ4 A;  2IK8 B;  1DK8 A;  3PVU A;  2JM5 A;  3PVW A;  5HE0 A;  3NYO A;  2V4Z B;  3UZT A;  3I5Q A;  1AGR E;  3PSC A;  3C7L A;  2DLV A;  2IHD A;  5HE2 A;  1EZY A;  3NYN A;  2ODE B;  5HE3 A;  1FQJ B;  4TND A;  2BV1 A;  2BCJ A;  4HTE A;  3C7K B;  2IHB B;  1CMZ A;  1FQI A;  2GTP C;  2JNU A;  2CRP A;  2OWI A;  3KRW A;  1OMW A;  5HE1 A;  4EKD B;  1EZT A;  2BT2 A;  5DO9 B;  5REQ B;  3CIK A;  4PNK A;  3QYF A;  4MK0 A;  1EMU A;  2D9J A; 
#chains in the Genus database with same CATH homology
 3KRX A;  2AF0 A;  2EBZ A;  4TNB A;  1FQK B;  3V5W A;  2OJ4 A;  2IK8 B;  1DK8 A;  3PVU A;  2JM5 A;  3PVW A;  5HE0 A;  3NYO A;  2V4Z B;  3UZT A;  1AGR E;  3PSC A;  3C7L A;  2DLV A;  2IHD A;  5HE2 A;  1EZY A;  3NYN A;  2ODE B;  5HE3 A;  1FQJ B;  4TND A;  2BV1 A;  2BCJ A;  3C7K B;  2IHB B;  1CMZ A;  1FQI A;  2GTP C;  2JNU A;  2CRP A;  2OWI A;  3KRW A;  1OMW A;  5HE1 A;  4EKD B;  1EZT A;  2BT2 A;  5DO9 B;  5REQ B;  3CIK A;  4PNK A;  3QYF A;  4MK0 A;  1EMU A;  2D9J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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