2EFLA

Crystal structure of the efc domain of formin-binding protein 17
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
288
structure length
281
Chain Sequence
MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKEYKYTSCKAFISNLNEMNDYAGQHEVISENMASQIIVDLARYVQELKQERKSNFHDGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQIRHQMAEDSKADYSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIVRMGESMKTYAEVDRQVIPIIGKCLDGIVKAAESIDQKNDSQLVIEAYKSGFEPPGDIEFEDYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Formin-binding protein 1
publication title Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis
pubmed doi rcsb
source organism Homo sapiens
molecule tags Endocytosis/exocytosis
total genus 116
structure length 281
sequence length 288
ec nomenclature
pdb deposition date 2007-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2eflA00
1I4TA 2EFLA 4FZSA 4I1QA 1WDZA 3LLLA 4H8SA 4AKVA 1I4LA 3QE6A 1X03A 3ABHA 3I2WA 4WPCA 2RAIA 2V0OA 4ATMA 1I49A 4WPEA 3QNIA 3Q0KA 3SYVA 3Q84A 3ACOA 3G9GA 3HAJA 1Y2OA 2Z0VA 1ZWWA 2ELBA 2Q12A 2Z0NA 3SOGA 2FICA 2Z0OA 4DYLA 4AVMA 3PLTA 2D1LA 2D4CA 2X3XA 5C5BB 3HAIA 4NQIA 2RAJA 2Q13A 3DYTA 4NSWA 4DCNC 2X3WA 3CAZA 3HAHA 1I4DA 2C08A 1X04A 2RAKA 3QWEA 3M3WA 4BNEA 5C5BA 3OK8A 2YKTA 2EFKA 1URUA 2X3VA
chains in the Genus database with same CATH superfamily
2EX3B 4JWIA 3QE6A 2WINM 1X03A 3T49A 3CZNA 3CVRA 4FZPA 1DKYA 3HAIA 4HR1A 3FD9A 3D51A 4IM3A 3DYTA 3DPQA 2X3WA 4UDXX 4AZ7A 4HYBA 2RAKA 2X3VA 4EZUA 1E2UA 4I1QA 4ATMA 1TQUA 3QNIA 2RT6A 3RV1A 2YIBA 3ERCC 1GN9A 3DDGA 3L3OM 4AZCB 1PS3A 2YKTA 3ER9B 3BUIA 2QKWA 3KAVA 2F18A 2OBLA 2V0OA 1W9MA 3QA8A 2ELBA 4E81A 4EZVA 3O3NB 4AZBA 3BVWA 2Q13A 2ND1A 3VEAA 4FZOA 5FIGA 3EJRA 2YI8A 2YIVX 3BVUA 3BUPA 4IWQA 4EZSA 4HY9A 3BUQA 3LLLA 3VKHA 3CKDA 4NPHA 2GAFD 3DPPA 3BVXA 4AVMA 1QX1A 1HXKA 4JNFA 3EJSA 4EZQA 2QFFA 4EZNA 4EZRA 3DX0A 3B51X 4AKVA 4R5KA 1I4LA 4WPCA 2ALWA 4R5JA 3ACOA 3ZEDA 2KHOA 2Z8YA 3DX4A 4M0MA 1MJGA 3BVVA 2PY6A 1X04A 3T46A 5C5BA 3LVTA 2OBMA 3OWGA 2N3KA 2O0I1 1DKZA 4AZGA 2ND0A 1I49A 1HTYA 5TKYA 4G6QA 1OAOA 3B52X 1SU8A 4AZIA 1QWNA 4JWCA 4JN4A 4PO2A 2ZXQA 2C08A 4R5LA 3VEBA 2EFKA 1URUA 2YLLA 1UPXA 1OA1A 1SUFA 4E3CA 2YL5A 3EJUA 3I2WA 3HAJA 1TQVA 1DKXA 3CV5A 4H6IA 2F1BA 4NQIA 3T48A 4EZOA 1SU6A 3O3OB 3PLTA 1JQKA 1TQTA 2OW7A 2NCZA 3QNJA 2F7QA 3OHXM 3T4AG 4HR1B 4AZ5A 4IW0A 4DYLA 4KIKA 3O3MB 4JWDA 1E1DA 2F1AA 2RAJA 2WYHA 3DX3A 5KBPA 4H8SA 1YWMA 2PMRA 4FM3A 3ABHA 2YI9A 2YL9A 4AZ6A 1QWUA 1R5EA 4IWOA 3CZSA 1U00A 3D2EA 4EZYA 2WYIA 4EZWA 3BLBA 3I39X 3DPOA 3D50A 4H6HA 3G9GA 1Y2OA 3BUBA 2FICA 1O7DC 2GF4A 2YLAA 2D1LA 3CAZA 3HAHA 1I4DA 3EJQA 2QXLA 3L3PA 2EFLA 3I01A 3KDRA 2EWFA 1GNLA 2D4CA 2JNSA 4F00A 4NSWA 1LQ7A 3OK8A 2F7OA 3I04A 2FYVA 3DX2A 4AZCA 4WPEA 3SYVA 4AZHA 2YL6A 2Z0NA 2Z0OA 2X5CA 5C5BB 4JLCA 4DCNC 4UDYX 2LXYA 3DDFA 5E84A 3GI7A 2YL8A 4BNEA 1R34A 1WDZA 3KAWA 4JWEA 2RAIA 4EZTA 1HWWA 2Z0VA 4R5GA 2OO2A 3D4YA 3EJPA 3DX1A 3LMFA 4IWPA 4EZXA 3T47A 4B9QA 4FZSA 3D52A 5FLEX 2OW6A 1TQWA 2YIAA 3Q84A 1OA0A 3B53X 3RV0A 3UITA 3BVTA 1O7DB 3QWEA 1ZYLA 3C7NA 3D4ZA 4EZPA 4KIKB 4JNEA 1R33A 3Q0KA 1TQSA 2Q12A 4IM2A 3F7WA 3SOGA 2X3XA 1GNTA 2JNKA 1SU7A 2F7PA 3M3WA 3A98A 1I4TA 3ER8C 1E9VA 2GA9D 4R5IA 4EZZA 2LM0A 2F7RA 2MI7A 1ZWWA 3D2FA 3EJTA 4JL9A 3BUDA 4D8JA 4IM0A 2OZNB 4F01A 3RPMA
chains in the Genus database with same CATH topology
1I4TA 2EFLA 4FZSA 4I1QA 1WDZA 3LLLA 4H8SA 4AKVA 1I4LA 3QE6A 1X03A 3ABHA 3I2WA 4WPCA 2RAIA 2V0OA 4ATMA 1I49A 4WPEA 3QNIA 3Q0KA 3SYVA 3Q84A 3ACOA 3G9GA 3HAJA 1Y2OA 2Z0VA 1ZWWA 2ELBA 2Q12A 2Z0NA 3SOGA 2FICA 2Z0OA 4DYLA 4AVMA 3PLTA 2D1LA 2D4CA 2X3XA 5C5BB 3HAIA 4NQIA 2RAJA 2Q13A 3DYTA 4NSWA 4DCNC 2X3WA 3CAZA 3HAHA 1I4DA 2C08A 1X04A 2RAKA 3QWEA 3M3WA 4BNEA 5C5BA 3OK8A 2YKTA 2EFKA 1URUA 2X3VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I4T A;  2EFL A;  4FZS A;  4I1Q A;  1WDZ A;  3LLL A;  4H8S A;  4AKV A;  1I4L A;  3QE6 A;  1X03 A;  3ABH A;  3I2W A;  4WPC A;  2RAI A;  2V0O A;  4ATM A;  1I49 A;  4WPE A;  3QNI A;  3Q0K A;  3SYV A;  3Q84 A;  3ACO A;  3G9G A;  3HAJ A;  1Y2O A;  2Z0V A;  1ZWW A;  2ELB A;  2Q12 A;  2Z0N A;  3SOG A;  2FIC A;  2Z0O A;  4DYL A;  4AVM A;  3PLT A;  2D1L A;  2D4C A;  2X3X A;  5C5B B;  3HAI A;  4NQI A;  2RAJ A;  2Q13 A;  3DYT A;  4NSW A;  4DCN C;  2X3W A;  3CAZ A;  3HAH A;  1I4D A;  2C08 A;  1X04 A;  2RAK A;  3QWE A;  3M3W A;  4BNE A;  5C5B A;  3OK8 A;  2YKT A;  2EFK A;  1URU A;  2X3V A; 
#chains in the Genus database with same CATH topology
 2EX3 B;  4JWI A;  3QE6 A;  2WIN M;  1X03 A;  3T49 A;  3CZN A;  3CVR A;  4FZP A;  1DKY A;  3HAI A;  4HR1 A;  3FD9 A;  3D51 A;  4IM3 A;  3DYT A;  3DPQ A;  2X3W A;  4UDX X;  4AZ7 A;  4HYB A;  2RAK A;  2X3V A;  4EZU A;  1E2U A;  4I1Q A;  4ATM A;  1TQU A;  3QNI A;  2RT6 A;  3RV1 A;  2YIB A;  3ERC C;  1GN9 A;  3DDG A;  3L3O M;  4AZC B;  1PS3 A;  2YKT A;  3ER9 B;  3BUI A;  2QKW A;  3KAV A;  2F18 A;  2OBL A;  2V0O A;  1W9M A;  3QA8 A;  2ELB A;  4E81 A;  4EZV A;  3O3N B;  4AZB A;  3BVW A;  2Q13 A;  2ND1 A;  3VEA A;  4FZO A;  5FIG A;  3EJR A;  2YI8 A;  2YIV X;  3BVU A;  3BUP A;  4IWQ A;  4EZS A;  4HY9 A;  3BUQ A;  3LLL A;  3VKH A;  3CKD A;  4NPH A;  2GAF D;  3DPP A;  3BVX A;  4AVM A;  1QX1 A;  1HXK A;  4JNF A;  3EJS A;  4EZQ A;  2QFF A;  4EZN A;  4EZR A;  3DX0 A;  3B51 X;  4AKV A;  4R5K A;  1I4L A;  4WPC A;  2ALW A;  4R5J A;  3ACO A;  3ZED A;  2KHO A;  2Z8Y A;  3DX4 A;  4M0M A;  1MJG A;  3BVV A;  2PY6 A;  1X04 A;  3T46 A;  5C5B A;  3LVT A;  2OBM A;  3OWG A;  2N3K A;  2O0I 1;  1DKZ A;  4AZG A;  2ND0 A;  1I49 A;  1HTY A;  5TKY A;  4G6Q A;  1OAO A;  3B52 X;  1SU8 A;  4AZI A;  1QWN A;  4JWC A;  4JN4 A;  4PO2 A;  2ZXQ A;  2C08 A;  4R5L A;  3VEB A;  2EFK A;  1URU A;  2YLL A;  1UPX A;  1OA1 A;  1SUF A;  4E3C A;  2YL5 A;  3EJU A;  3I2W A;  3HAJ A;  1TQV A;  1DKX A;  3CV5 A;  4H6I A;  2F1B A;  4NQI A;  3T48 A;  4EZO A;  1SU6 A;  3O3O B;  3PLT A;  1JQK A;  1TQT A;  2OW7 A;  2NCZ A;  3QNJ A;  2F7Q A;  3OHX M;  3T4A G;  4HR1 B;  4AZ5 A;  4IW0 A;  4DYL A;  4KIK A;  3O3M B;  4JWD A;  1E1D A;  2F1A A;  2RAJ A;  2WYH A;  3DX3 A;  5KBP A;  4H8S A;  1YWM A;  2PMR A;  4FM3 A;  3ABH A;  2YI9 A;  2YL9 A;  4AZ6 A;  1QWU A;  1R5E A;  4IWO A;  3CZS A;  1U00 A;  3D2E A;  4EZY A;  2WYI A;  4EZW A;  3BLB A;  3I39 X;  3DPO A;  3D50 A;  4H6H A;  3G9G A;  1Y2O A;  3BUB A;  2FIC A;  1O7D C;  2GF4 A;  2YLA A;  2D1L A;  3CAZ A;  3HAH A;  1I4D A;  3EJQ A;  2QXL A;  3L3P A;  2EFL A;  3I01 A;  3KDR A;  2EWF A;  1GNL A;  2D4C A;  2JNS A;  4F00 A;  4NSW A;  1LQ7 A;  3OK8 A;  2F7O A;  3I04 A;  2FYV A;  3DX2 A;  4AZC A;  4WPE A;  3SYV A;  4AZH A;  2YL6 A;  2Z0N A;  2Z0O A;  2X5C A;  5C5B B;  4JLC A;  4DCN C;  4UDY X;  2LXY A;  3DDF A;  5E84 A;  3GI7 A;  2YL8 A;  4BNE A;  1R34 A;  1WDZ A;  3KAW A;  4JWE A;  2RAI A;  4EZT A;  1HWW A;  2Z0V A;  4R5G A;  2OO2 A;  3D4Y A;  3EJP A;  3DX1 A;  3LMF A;  4IWP A;  4EZX A;  3T47 A;  4B9Q A;  4FZS A;  3D52 A;  5FLE X;  2OW6 A;  1TQW A;  2YIA A;  3Q84 A;  1OA0 A;  3B53 X;  3RV0 A;  3UIT A;  3BVT A;  1O7D B;  3QWE A;  1ZYL A;  3C7N A;  3D4Z A;  4EZP A;  4KIK B;  4JNE A;  1R33 A;  3Q0K A;  1TQS A;  2Q12 A;  4IM2 A;  3F7W A;  3SOG A;  2X3X A;  1GNT A;  2JNK A;  1SU7 A;  2F7P A;  3M3W A;  3A98 A;  1I4T A;  3ER8 C;  1E9V A;  2GA9 D;  4R5I A;  4EZZ A;  2LM0 A;  2F7R A;  2MI7 A;  1ZWW A;  3D2F A;  3EJT A;  4JL9 A;  3BUD A;  4D8J A;  4IM0 A;  2OZN B;  4F01 A;  3RPM A; 
#chains in the Genus database with same CATH homology
 1I4T A;  2EFL A;  4FZS A;  4I1Q A;  1WDZ A;  3LLL A;  4H8S A;  4AKV A;  1I4L A;  3QE6 A;  1X03 A;  3ABH A;  3I2W A;  4WPC A;  2RAI A;  2V0O A;  4ATM A;  1I49 A;  4WPE A;  3QNI A;  3Q0K A;  3SYV A;  3Q84 A;  3ACO A;  3G9G A;  3HAJ A;  1Y2O A;  2Z0V A;  1ZWW A;  2ELB A;  2Q12 A;  2Z0N A;  3SOG A;  2FIC A;  2Z0O A;  4DYL A;  4AVM A;  3PLT A;  2D1L A;  2D4C A;  2X3X A;  5C5B B;  3HAI A;  4NQI A;  2RAJ A;  2Q13 A;  3DYT A;  4NSW A;  4DCN C;  2X3W A;  3CAZ A;  3HAH A;  1I4D A;  2C08 A;  1X04 A;  2RAK A;  3QWE A;  3M3W A;  4BNE A;  5C5B A;  3OK8 A;  2YKT A;  2EFK A;  1URU A;  2X3V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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