2EFLA

Crystal structure of the efc domain of formin-binding protein 17
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
288
structure length
281
Chain Sequence
MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKEYKYTSCKAFISNLNEMNDYAGQHEVISENMASQIIVDLARYVQELKQERKSNFHDGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQIRHQMAEDSKADYSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIVRMGESMKTYAEVDRQVIPIIGKCLDGIVKAAESIDQKNDSQLVIEAYKSGFEPPGDIEFEDYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Formin-binding protein 1
publication title Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis
pubmed doi rcsb
source organism Homo sapiens
molecule tags Endocytosis/exocytosis
total genus 116
structure length 281
sequence length 288
ec nomenclature
pdb deposition date 2007-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2eflA00
2RAJA 3QWEA 2RAIA 4NQIA 2RAKA 2X3VA 2X3WA 3HAIA 4NSWA 1I49A 3SYVA 1X04A 1URUA 3G9GA 4H8SA 1I4DA 4FZSA 1I4LA 3OK8A 2EFLA 4AVMA 5C5BA 3PLTA 3LLLA 5C5BB 4WPEA 2Z0NA 3ABHA 2Q12A 2C08A 3CAZA 4WPCA 2D4CA 1I4TA 3SOGA 1WDZA 3M3WA 2Z0VA 3QE6A 3Q84A 4DCNC 2EFKA 3HAHA 3QNIA 1X03A 1Y2OA 3DYTA 4I1QA 2ELBA 4DYLA 1ZWWA 2V0OA 2Z0OA 3ACOA 2D1LA 4BNEA 3I2WA 2Q13A 4AKVA 3Q0KA 4ATMA 2YKTA 3HAJA 2FICA 2X3XA
chains in the Genus database with same CATH superfamily
3DDFA 3SYVA 1X04A 3RPMA 3OWGA 3OK8A 3BVXA 2F7QA 4JWEA 4IWOA 4EZXA 3UITA 3VKHA 2GA9D 2EFKA 4AZ7A 2O0I1 3EJQA 3EJRA 4E3CA 4EZPA 2F7RA 1YWMA 1E1DA 3ACOA 2D1LA 4HR1B 2N3KA 3RV1A 4IM0A 2YI9A 3T46A 2ALWA 3ABHA 4AZGA 2OBMA 3B53X 3QE6A 4AZ6A 3A98A 3GI7A 3F7WA 1TQVA 2Z0OA 3KAWA 4UDYX 4FM3A 4AZBA 2NCZA 2YL6A 3BUIA 4B9QA 4AZCB 4JWDA 3D51A 4I1QA 1GNLA 4DYLA 3DDGA 3EJSA 1TQTA 4AKVA 4ATMA 3DX4A 3T4AG 1HXKA 2EFLA 3PLTA 2RT6A 2D4CA 3SOGA 5E84A 4JWIA 2PMRA 3Q84A 4M0MA 1TQWA 3BUPA 4IM2A 3QA8A 3ER8C 4FZPA 2Q13A 2YL8A 2OW7A 4NSWA 3ZEDA 1U00A 4R5JA 1O7DC 2EX3B 4H8SA 2F1BA 3ERCC 5C5BB 2OO2A 2Z0VA 2JNKA 4R5KA 3QNIA 2JNSA 2OW6A 4D8JA 2ELBA 4IW0A 1O7DB 3DX1A 3HAJA 3O3MB 3D52A 4JL9A 3ER9B 3BUBA 4EZNA 4JNEA 4HY9A 2FYVA 1OA0A 2F1AA 2GF4A 1R34A 1TQUA 3I2WA 1QWNA 3BVUA 3CV5A 2YLLA 1I4DA 3LMFA 2EWFA 4EZUA 3B51X 2YIBA 3RV0A 4DCNC 4IWQA 1OA1A 4KIKA 2WINM 1PS3A 1SU8A 2V0OA 2YKTA 2X3XA 3L3OM 5KBPA 4EZQA 5FIGA 4JNFA 3DPQA 3T48A 3I39X 4H6HA 4AZHA 3DX3A 3DX0A 4JLCA 4HYBA 2YL5A 1HWWA 3CZSA 3CVRA 1QWUA 1E9VA 2F7OA 2QKWA 3BVVA 4AZIA 3T47A 1SUFA 3BLBA 3EJUA 3QWEA 2X3WA 2YI8A 4EZZA 4G6QA 2F7PA 4E81A 3KAVA 1GNTA 3FD9A 2LXYA 3D2EA 4HR1A 4EZYA 3DYTA 4F00A 4EZOA 2PY6A 4BNEA 4JN4A 2RAIA 2RAKA 1SU7A 1URUA 2LM0A 2YL9A 1DKYA 2YLAA 4WPEA 1LQ7A 4UDXX 3QNJA 1X03A 4JWCA 1Y2OA 1W9MA 3I01A 3LVTA 2QFFA 4EZRA 1I49A 4AZCA 4IM3A 3G9GA 2ND1A 1E2UA 2Z0NA 3OHXM 4WPCA 2YIAA 4PO2A 1QX1A 2F18A 3VEBA 2RAJA 3C7NA 3DPPA 4FZSA 3KDRA 1UPXA 4R5IA 3CKDA 2OZNB 1I4TA 4IWPA 3HAHA 2ND0A 2QXLA 3T49A 4FZOA 5C5BA 1DKXA 3CZNA 1MJGA 3BVWA 3D2FA 3D4ZA 4NPHA 3B52X 2GAFD 5FLEX 3BUQA 4EZSA 3O3NB 2Z8YA 3BUDA 3O3OB 3DPOA 2OBLA 4AVMA 4KIKB 4NQIA 3I04A 3D4YA 1R33A 4EZWA 1I4LA 3L3PA 3EJTA 3LLLA 1TQSA 1GN9A 3BVTA 4AZ5A 2YIVX 5TKYA 1WDZA 2ZXQA 3M3WA 3EJPA 4R5LA 4F01A 1ZWWA 1ZYLA 1OAOA 3Q0KA 1HTYA 2X3VA 3HAIA 2MI7A 4R5GA 1SU6A 1R5EA 4EZTA 2Q12A 2C08A 3CAZA 3D50A 4EZVA 2X5CA 4H6IA 1DKZA 3DX2A 1JQKA 2WYIA 2WYHA 2KHOA 2FICA 3VEAA
chains in the Genus database with same CATH topology
2RAJA 3QWEA 2RAIA 4NQIA 2RAKA 2X3VA 2X3WA 3HAIA 4NSWA 1I49A 3SYVA 1X04A 1URUA 3G9GA 4H8SA 1I4DA 4FZSA 1I4LA 3OK8A 2EFLA 4AVMA 5C5BA 3PLTA 3LLLA 5C5BB 4WPEA 2Z0NA 3ABHA 2Q12A 2C08A 3CAZA 4WPCA 2D4CA 1I4TA 3SOGA 1WDZA 3M3WA 2Z0VA 3QE6A 3Q84A 4DCNC 2EFKA 3HAHA 3QNIA 1X03A 1Y2OA 3DYTA 4I1QA 2ELBA 4DYLA 1ZWWA 2V0OA 2Z0OA 3ACOA 2D1LA 4BNEA 3I2WA 2Q13A 4AKVA 3Q0KA 4ATMA 2YKTA 3HAJA 2FICA 2X3XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RAJ A;  3QWE A;  2RAI A;  4NQI A;  2RAK A;  2X3V A;  2X3W A;  3HAI A;  4NSW A;  1I49 A;  3SYV A;  1X04 A;  1URU A;  3G9G A;  4H8S A;  1I4D A;  4FZS A;  1I4L A;  3OK8 A;  2EFL A;  4AVM A;  5C5B A;  3PLT A;  3LLL A;  5C5B B;  4WPE A;  2Z0N A;  3ABH A;  2Q12 A;  2C08 A;  3CAZ A;  4WPC A;  2D4C A;  1I4T A;  3SOG A;  1WDZ A;  3M3W A;  2Z0V A;  3QE6 A;  3Q84 A;  4DCN C;  2EFK A;  3HAH A;  3QNI A;  1X03 A;  1Y2O A;  3DYT A;  4I1Q A;  2ELB A;  4DYL A;  1ZWW A;  2V0O A;  2Z0O A;  3ACO A;  2D1L A;  4BNE A;  3I2W A;  2Q13 A;  4AKV A;  3Q0K A;  4ATM A;  2YKT A;  3HAJ A;  2FIC A;  2X3X A; 
#chains in the Genus database with same CATH topology
 3DDF A;  3SYV A;  1X04 A;  3RPM A;  3OWG A;  3OK8 A;  3BVX A;  2F7Q A;  4JWE A;  4IWO A;  4EZX A;  3UIT A;  3VKH A;  2GA9 D;  2EFK A;  4AZ7 A;  2O0I 1;  3EJQ A;  3EJR A;  4E3C A;  4EZP A;  2F7R A;  1YWM A;  1E1D A;  3ACO A;  2D1L A;  4HR1 B;  2N3K A;  3RV1 A;  4IM0 A;  2YI9 A;  3T46 A;  2ALW A;  3ABH A;  4AZG A;  2OBM A;  3B53 X;  3QE6 A;  4AZ6 A;  3A98 A;  3GI7 A;  3F7W A;  1TQV A;  2Z0O A;  3KAW A;  4UDY X;  4FM3 A;  4AZB A;  2NCZ A;  2YL6 A;  3BUI A;  4B9Q A;  4AZC B;  4JWD A;  3D51 A;  4I1Q A;  1GNL A;  4DYL A;  3DDG A;  3EJS A;  1TQT A;  4AKV A;  4ATM A;  3DX4 A;  3T4A G;  1HXK A;  2EFL A;  3PLT A;  2RT6 A;  2D4C A;  3SOG A;  5E84 A;  4JWI A;  2PMR A;  3Q84 A;  4M0M A;  1TQW A;  3BUP A;  4IM2 A;  3QA8 A;  3ER8 C;  4FZP A;  2Q13 A;  2YL8 A;  2OW7 A;  4NSW A;  3ZED A;  1U00 A;  4R5J A;  1O7D C;  2EX3 B;  4H8S A;  2F1B A;  3ERC C;  5C5B B;  2OO2 A;  2Z0V A;  2JNK A;  4R5K A;  3QNI A;  2JNS A;  2OW6 A;  4D8J A;  2ELB A;  4IW0 A;  1O7D B;  3DX1 A;  3HAJ A;  3O3M B;  3D52 A;  4JL9 A;  3ER9 B;  3BUB A;  4EZN A;  4JNE A;  4HY9 A;  2FYV A;  1OA0 A;  2F1A A;  2GF4 A;  1R34 A;  1TQU A;  3I2W A;  1QWN A;  3BVU A;  3CV5 A;  2YLL A;  1I4D A;  3LMF A;  2EWF A;  4EZU A;  3B51 X;  2YIB A;  3RV0 A;  4DCN C;  4IWQ A;  1OA1 A;  4KIK A;  2WIN M;  1PS3 A;  1SU8 A;  2V0O A;  2YKT A;  2X3X A;  3L3O M;  5KBP A;  4EZQ A;  5FIG A;  4JNF A;  3DPQ A;  3T48 A;  3I39 X;  4H6H A;  4AZH A;  3DX3 A;  3DX0 A;  4JLC A;  4HYB A;  2YL5 A;  1HWW A;  3CZS A;  3CVR A;  1QWU A;  1E9V A;  2F7O A;  2QKW A;  3BVV A;  4AZI A;  3T47 A;  1SUF A;  3BLB A;  3EJU A;  3QWE A;  2X3W A;  2YI8 A;  4EZZ A;  4G6Q A;  2F7P A;  4E81 A;  3KAV A;  1GNT A;  3FD9 A;  2LXY A;  3D2E A;  4HR1 A;  4EZY A;  3DYT A;  4F00 A;  4EZO A;  2PY6 A;  4BNE A;  4JN4 A;  2RAI A;  2RAK A;  1SU7 A;  1URU A;  2LM0 A;  2YL9 A;  1DKY A;  2YLA A;  4WPE A;  1LQ7 A;  4UDX X;  3QNJ A;  1X03 A;  4JWC A;  1Y2O A;  1W9M A;  3I01 A;  3LVT A;  2QFF A;  4EZR A;  1I49 A;  4AZC A;  4IM3 A;  3G9G A;  2ND1 A;  1E2U A;  2Z0N A;  3OHX M;  4WPC A;  2YIA A;  4PO2 A;  1QX1 A;  2F18 A;  3VEB A;  2RAJ A;  3C7N A;  3DPP A;  4FZS A;  3KDR A;  1UPX A;  4R5I A;  3CKD A;  2OZN B;  1I4T A;  4IWP A;  3HAH A;  2ND0 A;  2QXL A;  3T49 A;  4FZO A;  5C5B A;  1DKX A;  3CZN A;  1MJG A;  3BVW A;  3D2F A;  3D4Z A;  4NPH A;  3B52 X;  2GAF D;  5FLE X;  3BUQ A;  4EZS A;  3O3N B;  2Z8Y A;  3BUD A;  3O3O B;  3DPO A;  2OBL A;  4AVM A;  4KIK B;  4NQI A;  3I04 A;  3D4Y A;  1R33 A;  4EZW A;  1I4L A;  3L3P A;  3EJT A;  3LLL A;  1TQS A;  1GN9 A;  3BVT A;  4AZ5 A;  2YIV X;  5TKY A;  1WDZ A;  2ZXQ A;  3M3W A;  3EJP A;  4R5L A;  4F01 A;  1ZWW A;  1ZYL A;  1OAO A;  3Q0K A;  1HTY A;  2X3V A;  3HAI A;  2MI7 A;  4R5G A;  1SU6 A;  1R5E A;  4EZT A;  2Q12 A;  2C08 A;  3CAZ A;  3D50 A;  4EZV A;  2X5C A;  4H6I A;  1DKZ A;  3DX2 A;  1JQK A;  2WYI A;  2WYH A;  2KHO A;  2FIC A;  3VEA A; 
#chains in the Genus database with same CATH homology
 2RAJ A;  3QWE A;  2RAI A;  4NQI A;  2RAK A;  2X3V A;  2X3W A;  3HAI A;  4NSW A;  1I49 A;  3SYV A;  1X04 A;  1URU A;  3G9G A;  4H8S A;  1I4D A;  4FZS A;  1I4L A;  3OK8 A;  2EFL A;  4AVM A;  5C5B A;  3PLT A;  3LLL A;  5C5B B;  4WPE A;  2Z0N A;  3ABH A;  2Q12 A;  2C08 A;  3CAZ A;  4WPC A;  2D4C A;  1I4T A;  3SOG A;  1WDZ A;  3M3W A;  2Z0V A;  3QE6 A;  3Q84 A;  4DCN C;  2EFK A;  3HAH A;  3QNI A;  1X03 A;  1Y2O A;  3DYT A;  4I1Q A;  2ELB A;  4DYL A;  1ZWW A;  2V0O A;  2Z0O A;  3ACO A;  2D1L A;  4BNE A;  3I2W A;  2Q13 A;  4AKV A;  3Q0K A;  4ATM A;  2YKT A;  3HAJ A;  2FIC A;  2X3X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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