2EFLA

Crystal structure of the efc domain of formin-binding protein 17
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
288
structure length
281
Chain Sequence
b'MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKEYKYTSCKAFISNLNEMNDYAGQHEVISENMASQIIVDLARYVQELKQERKSNFHDGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQIRHQMAEDSKADYSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIVRMGESMKTYAEVDRQVIPIIGKCLDGIVKAAESIDQKNDSQLVIEAYKSGFEPPGDIEFEDYT'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Formin-binding protein 1
publication title Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis
pubmed doi rcsb
source organism Homo sapiens
molecule tags Endocytosis/exocytosis
total genus 116
structure length 281
sequence length 288
ec nomenclature
pdb deposition date 2007-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2eflA00
4WPCA 1I49A 2RAKA 2YKTA 2X3VA 4WPEA 1X03A 2D4CA 3I2WA 3ABHA 2Z0OA 3G9GA 3M3WA 3OK8A 4ATMA 1I4LA 4FZSA 3QWEA 4DCNC 1I4TA 4AVMA 2FICA 1X04A 2RAJA 2V0OA 2EFKA 1ZWWA 2C08A 2Z0NA 4H8SA 2Q13A 2X3WA 4NSWA 5C5BB 3SOGA 3QNIA 4AKVA 3SYVA 2Z0VA 3Q0KA 3QE6A 3HAJA 3CAZA 1URUA 3HAHA 3LLLA 4NQIA 4DYLA 5C5BA 1I4DA 2RAIA 2D1LA 3PLTA 1WDZA 3HAIA 3ACOA 4BNEA 2EFLA 2Q12A 2X3XA 1Y2OA 3DYTA 3Q84A 4I1QA 2ELBA
chains in the Genus database with same CATH superfamily
4IWPA 4EZVA 3T46A 1R5EA 1TQSA 4AZCB 2C08A 4NSWA 2YIAA 3BVXA 3HAHA 3DX2A 4DYLA 3DX3A 4BNEA 1SU6A 2Q12A 3EJUA 1YWMA 2OBLA 3RPMA 2NCZA 4EZSA 3M3WA 3VEBA 3T48A 1PS3A 3ZEDA 4H8SA 4JWEA 3LVTA 3HAIA 2QXLA 3RV0A 4IW0A 1TQUA 3L3PA 3G9GA 4IM0A 4EZNA 2ZXQA 3CKDA 3DDGA 3DDFA 3QNIA 4IM3A 3DPQA 2YL6A 3BUBA 1OAOA 3F7WA 3DYTA 3DX4A 3D50A 3BUDA 2X3VA 3I2WA 4FZOA 3QWEA 3T47A 4AZIA 1I4TA 3SOGA 2X3WA 2MI7A 3CV5A 4JWDA 1JQKA 2EWFA 3PLTA 3OWGA 4EZWA 1HXKA 4KIKA 2F7PA 1DKYA 4D8JA 3CZSA 4WPEA 3D4ZA 4HY9A 1X04A 2EFKA 3BVTA 2YL9A 2QKWA 3BLBA 2D1LA 4JN4A 3T49A 3ACOA 3KDRA 3I39X 3EJSA 2D4CA 4AZCA 2F7RA 2JNKA 2O0I1 2YIVX 1WDZA 2QFFA 3DPOA 3I04A 4JNFA 3UITA 2OO2A 1E9VA 3D2EA 5KBPA 2OW7A 4G6QA 2Z8YA 4AZHA 4JWCA 3Q0KA 4EZRA 1UPXA 3BUQA 5FIGA 2EFLA 3VKHA 2YLLA 4EZZA 5E84A 2F18A 4AZGA 4EZYA 3CVRA 1OA0A 4AZ5A 3CZNA 3D4YA 4AVMA 1E1DA 1QWNA 2F7OA 2JNSA 1HTYA 2WINM 3HAJA 5C5BA 3D52A 4R5GA 2WYIA 3B51X 1Y2OA 3QA8A 1R33A 3B52X 4E3CA 2PY6A 2GF4A 1R34A 3OK8A 1I4LA 4EZPA 4E81A 5FLEX 2OZNB 1SU7A 1URUA 3DX0A 3BVWA 4AKVA 1TQTA 1U00A 2YI9A 3GI7A 4IM2A 4EZXA 3O3NB 1GNLA 3I01A 3EJPA 1QWUA 4FZPA 2ND1A 2YL5A 3QE6A 2ND0A 1DKXA 3DPPA 4HR1A 3OHXM 2LM0A 2ELBA 4WPCA 3QNJA 1GN9A 3ER9B 1X03A 2YIBA 2V0OA 1E2UA 2Z0NA 2F7QA 3KAWA 2Q13A 2GAFD 4FM3A 4I1QA 2F1AA 4AZ6A 4EZOA 3A98A 3LMFA 2X5CA 2Z0OA 2KHOA 1LQ7A 1SU8A 2EX3B 1W9MA 3SYVA 4JLCA 1HWWA 3BUIA 3BUPA 2X3XA 1TQVA 1I49A 2OBMA 4M0MA 4EZTA 3ER8C 4NPHA 4ATMA 4DCNC 2RAJA 1ZWWA 3D2FA 4IWQA 3VEAA 4JWIA 3BVVA 4NQIA 2WYHA 2RAIA 2N3KA 4JL9A 1OA1A 1O7DC 2PMRA 3Q84A 3EJTA 5TKYA 2RAKA 3T4AG 3D51A 4F01A 4R5JA 4H6IA 2YL8A 3O3MB 4FZSA 3C7NA 2FYVA 5C5BB 2F1BA 4EZQA 4R5LA 2Z0VA 3BVUA 1SUFA 2ALWA 1ZYLA 4UDYX 3EJRA 4AZBA 4IWOA 1QX1A 4JNEA 4R5IA 4F00A 3ABHA 3O3OB 3KAVA 2YI8A 3LLLA 1O7DB 1I4DA 4R5KA 3B53X 4KIKB 4B9QA 4HYBA 2LXYA 2YLAA 3RV1A 2OW6A 2YKTA 4UDXX 1DKZA 3L3OM 4AZ7A 2FICA 4PO2A 3ERCC 3FD9A 2GA9D 4H6HA 2RT6A 1GNTA 4HR1B 3CAZA 1TQWA 3DX1A 3EJQA 1MJGA 4EZUA
chains in the Genus database with same CATH topology
4WPCA 1I49A 2RAKA 2YKTA 2X3VA 4WPEA 1X03A 2D4CA 3I2WA 3ABHA 2Z0OA 3G9GA 3M3WA 3OK8A 4ATMA 1I4LA 4FZSA 3QWEA 4DCNC 1I4TA 4AVMA 2FICA 1X04A 2RAJA 2V0OA 2EFKA 1ZWWA 2C08A 2Z0NA 4H8SA 2Q13A 2X3WA 4NSWA 5C5BB 3SOGA 3QNIA 4AKVA 3SYVA 2Z0VA 3Q0KA 3QE6A 3HAJA 3CAZA 1URUA 3HAHA 3LLLA 4NQIA 4DYLA 5C5BA 1I4DA 2RAIA 2D1LA 3PLTA 1WDZA 3HAIA 3ACOA 4BNEA 2EFLA 2Q12A 2X3XA 1Y2OA 3DYTA 3Q84A 4I1QA 2ELBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WPC A;  1I49 A;  2RAK A;  2YKT A;  2X3V A;  4WPE A;  1X03 A;  2D4C A;  3I2W A;  3ABH A;  2Z0O A;  3G9G A;  3M3W A;  3OK8 A;  4ATM A;  1I4L A;  4FZS A;  3QWE A;  4DCN C;  1I4T A;  4AVM A;  2FIC A;  1X04 A;  2RAJ A;  2V0O A;  2EFK A;  1ZWW A;  2C08 A;  2Z0N A;  4H8S A;  2Q13 A;  2X3W A;  4NSW A;  5C5B B;  3SOG A;  3QNI A;  4AKV A;  3SYV A;  2Z0V A;  3Q0K A;  3QE6 A;  3HAJ A;  3CAZ A;  1URU A;  3HAH A;  3LLL A;  4NQI A;  4DYL A;  5C5B A;  1I4D A;  2RAI A;  2D1L A;  3PLT A;  1WDZ A;  3HAI A;  3ACO A;  4BNE A;  2EFL A;  2Q12 A;  2X3X A;  1Y2O A;  3DYT A;  3Q84 A;  4I1Q A;  2ELB A; 
#chains in the Genus database with same CATH topology
 4IWP A;  4EZV A;  3T46 A;  1R5E A;  1TQS A;  4AZC B;  2C08 A;  4NSW A;  2YIA A;  3BVX A;  3HAH A;  3DX2 A;  4DYL A;  3DX3 A;  4BNE A;  1SU6 A;  2Q12 A;  3EJU A;  1YWM A;  2OBL A;  3RPM A;  2NCZ A;  4EZS A;  3M3W A;  3VEB A;  3T48 A;  1PS3 A;  3ZED A;  4H8S A;  4JWE A;  3LVT A;  3HAI A;  2QXL A;  3RV0 A;  4IW0 A;  1TQU A;  3L3P A;  3G9G A;  4IM0 A;  4EZN A;  2ZXQ A;  3CKD A;  3DDG A;  3DDF A;  3QNI A;  4IM3 A;  3DPQ A;  2YL6 A;  3BUB A;  1OAO A;  3F7W A;  3DYT A;  3DX4 A;  3D50 A;  3BUD A;  2X3V A;  3I2W A;  4FZO A;  3QWE A;  3T47 A;  4AZI A;  1I4T A;  3SOG A;  2X3W A;  2MI7 A;  3CV5 A;  4JWD A;  1JQK A;  2EWF A;  3PLT A;  3OWG A;  4EZW A;  1HXK A;  4KIK A;  2F7P A;  1DKY A;  4D8J A;  3CZS A;  4WPE A;  3D4Z A;  4HY9 A;  1X04 A;  2EFK A;  3BVT A;  2YL9 A;  2QKW A;  3BLB A;  2D1L A;  4JN4 A;  3T49 A;  3ACO A;  3KDR A;  3I39 X;  3EJS A;  2D4C A;  4AZC A;  2F7R A;  2JNK A;  2O0I 1;  2YIV X;  1WDZ A;  2QFF A;  3DPO A;  3I04 A;  4JNF A;  3UIT A;  2OO2 A;  1E9V A;  3D2E A;  5KBP A;  2OW7 A;  4G6Q A;  2Z8Y A;  4AZH A;  4JWC A;  3Q0K A;  4EZR A;  1UPX A;  3BUQ A;  5FIG A;  2EFL A;  3VKH A;  2YLL A;  4EZZ A;  5E84 A;  2F18 A;  4AZG A;  4EZY A;  3CVR A;  1OA0 A;  4AZ5 A;  3CZN A;  3D4Y A;  4AVM A;  1E1D A;  1QWN A;  2F7O A;  2JNS A;  1HTY A;  2WIN M;  3HAJ A;  5C5B A;  3D52 A;  4R5G A;  2WYI A;  3B51 X;  1Y2O A;  3QA8 A;  1R33 A;  3B52 X;  4E3C A;  2PY6 A;  2GF4 A;  1R34 A;  3OK8 A;  1I4L A;  4EZP A;  4E81 A;  5FLE X;  2OZN B;  1SU7 A;  1URU A;  3DX0 A;  3BVW A;  4AKV A;  1TQT A;  1U00 A;  2YI9 A;  3GI7 A;  4IM2 A;  4EZX A;  3O3N B;  1GNL A;  3I01 A;  3EJP A;  1QWU A;  4FZP A;  2ND1 A;  2YL5 A;  3QE6 A;  2ND0 A;  1DKX A;  3DPP A;  4HR1 A;  3OHX M;  2LM0 A;  2ELB A;  4WPC A;  3QNJ A;  1GN9 A;  3ER9 B;  1X03 A;  2YIB A;  2V0O A;  1E2U A;  2Z0N A;  2F7Q A;  3KAW A;  2Q13 A;  2GAF D;  4FM3 A;  4I1Q A;  2F1A A;  4AZ6 A;  4EZO A;  3A98 A;  3LMF A;  2X5C A;  2Z0O A;  2KHO A;  1LQ7 A;  1SU8 A;  2EX3 B;  1W9M A;  3SYV A;  4JLC A;  1HWW A;  3BUI A;  3BUP A;  2X3X A;  1TQV A;  1I49 A;  2OBM A;  4M0M A;  4EZT A;  3ER8 C;  4NPH A;  4ATM A;  4DCN C;  2RAJ A;  1ZWW A;  3D2F A;  4IWQ A;  3VEA A;  4JWI A;  3BVV A;  4NQI A;  2WYH A;  2RAI A;  2N3K A;  4JL9 A;  1OA1 A;  1O7D C;  2PMR A;  3Q84 A;  3EJT A;  5TKY A;  2RAK A;  3T4A G;  3D51 A;  4F01 A;  4R5J A;  4H6I A;  2YL8 A;  3O3M B;  4FZS A;  3C7N A;  2FYV A;  5C5B B;  2F1B A;  4EZQ A;  4R5L A;  2Z0V A;  3BVU A;  1SUF A;  2ALW A;  1ZYL A;  4UDY X;  3EJR A;  4AZB A;  4IWO A;  1QX1 A;  4JNE A;  4R5I A;  4F00 A;  3ABH A;  3O3O B;  3KAV A;  2YI8 A;  3LLL A;  1O7D B;  1I4D A;  4R5K A;  3B53 X;  4KIK B;  4B9Q A;  4HYB A;  2LXY A;  2YLA A;  3RV1 A;  2OW6 A;  2YKT A;  4UDX X;  1DKZ A;  3L3O M;  4AZ7 A;  2FIC A;  4PO2 A;  3ERC C;  3FD9 A;  2GA9 D;  4H6H A;  2RT6 A;  1GNT A;  4HR1 B;  3CAZ A;  1TQW A;  3DX1 A;  3EJQ A;  1MJG A;  4EZU A; 
#chains in the Genus database with same CATH homology
 4WPC A;  1I49 A;  2RAK A;  2YKT A;  2X3V A;  4WPE A;  1X03 A;  2D4C A;  3I2W A;  3ABH A;  2Z0O A;  3G9G A;  3M3W A;  3OK8 A;  4ATM A;  1I4L A;  4FZS A;  3QWE A;  4DCN C;  1I4T A;  4AVM A;  2FIC A;  1X04 A;  2RAJ A;  2V0O A;  2EFK A;  1ZWW A;  2C08 A;  2Z0N A;  4H8S A;  2Q13 A;  2X3W A;  4NSW A;  5C5B B;  3SOG A;  3QNI A;  4AKV A;  3SYV A;  2Z0V A;  3Q0K A;  3QE6 A;  3HAJ A;  3CAZ A;  1URU A;  3HAH A;  3LLL A;  4NQI A;  4DYL A;  5C5B A;  1I4D A;  2RAI A;  2D1L A;  3PLT A;  1WDZ A;  3HAI A;  3ACO A;  4BNE A;  2EFL A;  2Q12 A;  2X3X A;  1Y2O A;  3DYT A;  3Q84 A;  4I1Q A;  2ELB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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