2EGBA

Crystal structure of glu140 to asn mutant of diphthine synthase
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPNGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2007-02-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2egbA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2egbA01
2PB5A 2E07A 2ED3A 2OWKA 2EJKA 2P5CA 2EKAA 2PCGA 2EHCA 3NUTA 2PCMA 2EN5A 2E15A 2E8RA 2EJJA 2EMUA 2EMRA 2P6LA 2P9DA 2EGSA 2E4RA 1WDEA 2EHLA 3FQ6A 1S4DA 2EK3A 3FFYA 2E08A 2EL3A 1VA0A 2EJZA 2EK4A 3NEIA 2CBFA 2EL2A 2PCAA 2HUXA 3I4TA 2EEQA 2PCKA 2EGLA 1VCEA 2HR8A 3NDCA 2EK2A 2DV4A 2HUVA 2DSIA 2P5FA 2E7RA 2EH4A 2DEKA 1WNGA 2DV3A 2DXWA 2Z6RA 2P6KA 2OWGA 2DV7A 3ND1A 2P6IA 1PJQA 2DV5A 2DSHA 2DXVA 2PCHA 2EGBA 2ENIA 3KWPA 1VHVA 1PJSA 1WYZA 2E0KA 2YBOA 2EH5A 2ELEA 2EL1A 2ZVBA 2OWFA 2PB6A 1V9AA 2EH2A 2ELDA 5HW4A 2E0NA 2DXXA 2E16A 2OWUA 2E8QA 2EK7A 3HH1A 2EL0A 2ZVCA 2DSGA 2ED5A 1PJTA 2NPNA 2P6DA 2PB4A 2E17A 1CBFA 2E4NA 2HUQA 2E8SA 2E8HA 1VE2A 2BB3A 2P2XA 2QBUA 2OWVA 4E16A 2YBQA 2HUTA 2PCIA
chains in the Genus database with same CATH superfamily
2PB5A 2E07A 2ED3A 2OWKA 2EJKA 2P5CA 3KE9A 2EKAA 2PCGA 2EHCA 3NUTA 2PCMA 2EN5A 4MV0A 3LMMA 4MV5A 2E15A 2E8RA 2EJJA 2EMUA 3KE8A 2EMRA 4H4EA 2P6LA 4H4CA 2P9DA 2EGSA 3KEMA 3SZOA 2E4RA 1WDEA 2EHLA 3FQ6A 1S4DA 2EK3A 3FFYA 2E08A 2EL3A 1VA0A 2EJZA 2EK4A 3NEIA 3SZUA 2KYYA 2CBFA 2EL2A 2PCAA 2HUXA 3I4TA 3T0GA 3UV6A 2EEQA 4H4DA 2PCKA 4N7BA 2EGLA 1VCEA 2HR8A 3NDCA 3URKA 2EK2A 3UV3A 2DV4A 2HUVA 4MUYA 2DSIA 2P5FA 2E7RA 2EH4A 2DEKA 1WNGA 3SZLA 2DV3A 2DXWA 2Z6RA 2P6KA 2OWGA 2DV7A 3ND1A 2P6IA 1PJQA 2DV5A 2DSHA 4MUXA 3TIXB 2DXVA 2PCHA 2EGBA 4EB3A 2ENIA 3KWPA 1VHVA 1PJSA 1WYZA 2E0KA 2YBOA 2EH5A 2ELEA 2EL1A 3UTCA 2ZVBA 3DNFA 3KELA 2OWFA 2PB6A 3F7TA 3ZGLA 1V9AA 2EH2A 3KEFA 2ELDA 5HW4A 2E0NA 2DXXA 2E16A 3UWMA 2OWUA 2E8QA 2EK7A 3HH1A 2EL0A 2ZVCA 3T0FA 2DSGA 2ED5A 3UV7A 1PJTA 2NPNA 3ZGNA 2P6DA 2PB4A 2E17A 1CBFA 2E4NA 2HUQA 2E8SA 2E8HA 1VE2A 3UTDA 2BB3A 2P2XA 2QBUA 2OWVA 4E16A 2YBQA 2HUTA 2PCIA
chains in the Genus database with same CATH topology
2PB5A 2E07A 2ED3A 2OWKA 2EJKA 2P5CA 3KE9A 2EKAA 2PCGA 2EHCA 3NUTA 2PCMA 2EN5A 4MV0A 3LMMA 4MV5A 2E15A 2E8RA 2EJJA 2EMUA 3KE8A 2EMRA 4H4EA 2P6LA 4H4CA 2P9DA 2EGSA 3KEMA 3SZOA 2E4RA 1WDEA 2EHLA 3FQ6A 1S4DA 2EK3A 3FFYA 2E08A 2EL3A 1VA0A 2EJZA 2EK4A 3NEIA 3SZUA 2KYYA 2CBFA 2EL2A 2PCAA 2HUXA 3I4TA 3T0GA 3UV6A 2EEQA 4H4DA 2PCKA 4N7BA 2EGLA 1VCEA 2HR8A 3NDCA 3URKA 2EK2A 3UV3A 2DV4A 2HUVA 4MUYA 2DSIA 2P5FA 2E7RA 2EH4A 2DEKA 1WNGA 3SZLA 2DV3A 2DXWA 2Z6RA 2P6KA 2OWGA 2DV7A 3ND1A 2P6IA 1PJQA 2DV5A 2DSHA 4MUXA 3TIXB 2DXVA 2PCHA 2EGBA 4EB3A 2ENIA 3KWPA 1VHVA 1PJSA 1WYZA 2E0KA 2YBOA 2EH5A 2ELEA 2EL1A 3UTCA 2ZVBA 3DNFA 3KELA 2OWFA 2PB6A 3F7TA 3ZGLA 1V9AA 2EH2A 3KEFA 2ELDA 5HW4A 2E0NA 2DXXA 2E16A 3UWMA 2OWUA 2E8QA 2EK7A 3HH1A 2EL0A 2ZVCA 3T0FA 2DSGA 2ED5A 3UV7A 1PJTA 2NPNA 3ZGNA 2P6DA 2PB4A 2E17A 1CBFA 2E4NA 2HUQA 2E8SA 2E8HA 1VE2A 3UTDA 2BB3A 2P2XA 2QBUA 2OWVA 4E16A 2YBQA 2HUTA 2PCIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PB5 A;  2E07 A;  2ED3 A;  2OWK A;  2EJK A;  2P5C A;  2EKA A;  2PCG A;  2EHC A;  3NUT A;  2PCM A;  2EN5 A;  2E15 A;  2E8R A;  2EJJ A;  2EMU A;  2EMR A;  2P6L A;  2P9D A;  2EGS A;  2E4R A;  1WDE A;  2EHL A;  3FQ6 A;  1S4D A;  2EK3 A;  3FFY A;  2E08 A;  2EL3 A;  1VA0 A;  2EJZ A;  2EK4 A;  3NEI A;  2CBF A;  2EL2 A;  2PCA A;  2HUX A;  3I4T A;  2EEQ A;  2PCK A;  2EGL A;  1VCE A;  2HR8 A;  3NDC A;  2EK2 A;  2DV4 A;  2HUV A;  2DSI A;  2P5F A;  2E7R A;  2EH4 A;  2DEK A;  1WNG A;  2DV3 A;  2DXW A;  2Z6R A;  2P6K A;  2OWG A;  2DV7 A;  3ND1 A;  2P6I A;  1PJQ A;  2DV5 A;  2DSH A;  2DXV A;  2PCH A;  2EGB A;  2ENI A;  3KWP A;  1VHV A;  1PJS A;  1WYZ A;  2E0K A;  2YBO A;  2EH5 A;  2ELE A;  2EL1 A;  2ZVB A;  2OWF A;  2PB6 A;  1V9A A;  2EH2 A;  2ELD A;  5HW4 A;  2E0N A;  2DXX A;  2E16 A;  2OWU A;  2E8Q A;  2EK7 A;  3HH1 A;  2EL0 A;  2ZVC A;  2DSG A;  2ED5 A;  1PJT A;  2NPN A;  2P6D A;  2PB4 A;  2E17 A;  1CBF A;  2E4N A;  2HUQ A;  2E8S A;  2E8H A;  1VE2 A;  2BB3 A;  2P2X A;  2QBU A;  2OWV A;  4E16 A;  2YBQ A;  2HUT A;  2PCI A; 
#chains in the Genus database with same CATH topology
 2PB5 A;  2E07 A;  2ED3 A;  2OWK A;  2EJK A;  2P5C A;  3KE9 A;  2EKA A;  2PCG A;  2EHC A;  3NUT A;  2PCM A;  2EN5 A;  4MV0 A;  3LMM A;  4MV5 A;  2E15 A;  2E8R A;  2EJJ A;  2EMU A;  3KE8 A;  2EMR A;  4H4E A;  2P6L A;  4H4C A;  2P9D A;  2EGS A;  3KEM A;  3SZO A;  2E4R A;  1WDE A;  2EHL A;  3FQ6 A;  1S4D A;  2EK3 A;  3FFY A;  2E08 A;  2EL3 A;  1VA0 A;  2EJZ A;  2EK4 A;  3NEI A;  3SZU A;  2KYY A;  2CBF A;  2EL2 A;  2PCA A;  2HUX A;  3I4T A;  3T0G A;  3UV6 A;  2EEQ A;  4H4D A;  2PCK A;  4N7B A;  2EGL A;  1VCE A;  2HR8 A;  3NDC A;  3URK A;  2EK2 A;  3UV3 A;  2DV4 A;  2HUV A;  4MUY A;  2DSI A;  2P5F A;  2E7R A;  2EH4 A;  2DEK A;  1WNG A;  3SZL A;  2DV3 A;  2DXW A;  2Z6R A;  2P6K A;  2OWG A;  2DV7 A;  3ND1 A;  2P6I A;  1PJQ A;  2DV5 A;  2DSH A;  4MUX A;  3TIX B;  2DXV A;  2PCH A;  2EGB A;  4EB3 A;  2ENI A;  3KWP A;  1VHV A;  1PJS A;  1WYZ A;  2E0K A;  2YBO A;  2EH5 A;  2ELE A;  2EL1 A;  3UTC A;  2ZVB A;  3DNF A;  3KEL A;  2OWF A;  2PB6 A;  3F7T A;  3ZGL A;  1V9A A;  2EH2 A;  3KEF A;  2ELD A;  5HW4 A;  2E0N A;  2DXX A;  2E16 A;  3UWM A;  2OWU A;  2E8Q A;  2EK7 A;  3HH1 A;  2EL0 A;  2ZVC A;  3T0F A;  2DSG A;  2ED5 A;  3UV7 A;  1PJT A;  2NPN A;  3ZGN A;  2P6D A;  2PB4 A;  2E17 A;  1CBF A;  2E4N A;  2HUQ A;  2E8S A;  2E8H A;  1VE2 A;  3UTD A;  2BB3 A;  2P2X A;  2QBU A;  2OWV A;  4E16 A;  2YBQ A;  2HUT A;  2PCI A; 
#chains in the Genus database with same CATH homology
 2PB5 A;  2E07 A;  2ED3 A;  2OWK A;  2EJK A;  2P5C A;  3KE9 A;  2EKA A;  2PCG A;  2EHC A;  3NUT A;  2PCM A;  2EN5 A;  4MV0 A;  3LMM A;  4MV5 A;  2E15 A;  2E8R A;  2EJJ A;  2EMU A;  3KE8 A;  2EMR A;  4H4E A;  2P6L A;  4H4C A;  2P9D A;  2EGS A;  3KEM A;  3SZO A;  2E4R A;  1WDE A;  2EHL A;  3FQ6 A;  1S4D A;  2EK3 A;  3FFY A;  2E08 A;  2EL3 A;  1VA0 A;  2EJZ A;  2EK4 A;  3NEI A;  3SZU A;  2KYY A;  2CBF A;  2EL2 A;  2PCA A;  2HUX A;  3I4T A;  3T0G A;  3UV6 A;  2EEQ A;  4H4D A;  2PCK A;  4N7B A;  2EGL A;  1VCE A;  2HR8 A;  3NDC A;  3URK A;  2EK2 A;  3UV3 A;  2DV4 A;  2HUV A;  4MUY A;  2DSI A;  2P5F A;  2E7R A;  2EH4 A;  2DEK A;  1WNG A;  3SZL A;  2DV3 A;  2DXW A;  2Z6R A;  2P6K A;  2OWG A;  2DV7 A;  3ND1 A;  2P6I A;  1PJQ A;  2DV5 A;  2DSH A;  4MUX A;  3TIX B;  2DXV A;  2PCH A;  2EGB A;  4EB3 A;  2ENI A;  3KWP A;  1VHV A;  1PJS A;  1WYZ A;  2E0K A;  2YBO A;  2EH5 A;  2ELE A;  2EL1 A;  3UTC A;  2ZVB A;  3DNF A;  3KEL A;  2OWF A;  2PB6 A;  3F7T A;  3ZGL A;  1V9A A;  2EH2 A;  3KEF A;  2ELD A;  5HW4 A;  2E0N A;  2DXX A;  2E16 A;  3UWM A;  2OWU A;  2E8Q A;  2EK7 A;  3HH1 A;  2EL0 A;  2ZVC A;  3T0F A;  2DSG A;  2ED5 A;  3UV7 A;  1PJT A;  2NPN A;  3ZGN A;  2P6D A;  2PB4 A;  2E17 A;  1CBF A;  2E4N A;  2HUQ A;  2E8S A;  2E8H A;  1VE2 A;  3UTD A;  2BB3 A;  2P2X A;  2QBU A;  2OWV A;  4E16 A;  2YBQ A;  2HUT A;  2PCI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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