2EGSA

Crystal structure of leu261 to met mutant of diphthine synthase
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
265
structure length
265
Chain Sequence
b'MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREIMRVNV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords diphthine synthase
publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
total genus 80
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2egsA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2egsA01
2EMUA 2DSGA 2EEQA 2PCAA 2ZVBA 2DEKA 2ZVCA 3NDCA 2PCIA 2OWVA 3NUTA 2HUVA 1V9AA 2DXWA 3FQ6A 3KWPA 2OWUA 3I4TA 2E8HA 2OWGA 2EL0A 2HUQA 2E0NA 1PJTA 2DV5A 2P9DA 2P6LA 1PJQA 2EGBA 2DV4A 2PCMA 2EMRA 2EH4A 2EKAA 2EK4A 2P5FA 1PJSA 2EHLA 2ED3A 1S4DA 2E8RA 2EL3A 1VA0A 2DSIA 2E8QA 2P6KA 2P6DA 4E16A 2Z6RA 2E4RA 5HW4A 2E8SA 2EK2A 2EGSA 2EJZA 2EH5A 2OWFA 2PCKA 2EK7A 3ND1A 2YBOA 1VE2A 2EL1A 2DSHA 2E07A 2EHCA 2P2XA 1WYZA 2ED5A 2HR8A 2HUTA 2PB5A 2E7RA 2P6IA 2P5CA 2HUXA 3FFYA 2EJKA 2E16A 2EGLA 2PCHA 2ELDA 2EH2A 2EL2A 3NEIA 3HH1A 2E08A 2E4NA 1CBFA 2EK3A 1WDEA 1WNGA 2DXXA 2PB6A 2EJJA 2ENIA 2DV7A 2CBFA 2NPNA 2YBQA 2E0KA 1VCEA 2PCGA 2PB4A 2ELEA 2E15A 2QBUA 1VHVA 2DV3A 2BB3A 2E17A 2DXVA 2EN5A 2OWKA
chains in the Genus database with same CATH superfamily
2EMUA 2DSGA 3KE8A 4N7BA 3ZGNA 2EEQA 2PCAA 2ZVBA 2DEKA 3UTCA 2ZVCA 3SZOA 3NDCA 3KEMA 2PCIA 2OWVA 3NUTA 2HUVA 1V9AA 2DXWA 3FQ6A 3KWPA 2OWUA 3I4TA 2E8HA 2OWGA 2EL0A 2HUQA 2E0NA 1PJTA 3KELA 2DV5A 2P9DA 4H4CA 2P6LA 1PJQA 2EGBA 3UV3A 2DV4A 2PCMA 2EMRA 2EH4A 2EKAA 3KEFA 2EK4A 2P5FA 1PJSA 2EHLA 2ED3A 1S4DA 2E8RA 2EL3A 1VA0A 2DSIA 2E8QA 2P6KA 2P6DA 4E16A 2Z6RA 2E4RA 4EB3A 5HW4A 2E8SA 2EK2A 2EGSA 2EJZA 2EH5A 2OWFA 2PCKA 3SZUA 2EK7A 3ND1A 2YBOA 1VE2A 3TIXB 2EL1A 2DSHA 2E07A 3URKA 2EHCA 2P2XA 1WYZA 2ED5A 2HR8A 2HUTA 2PB5A 2E7RA 2P6IA 2P5CA 2HUXA 3T0FA 3FFYA 2EJKA 2E16A 2EGLA 4MV5A 4MUYA 2PCHA 2ELDA 2EH2A 2EL2A 3UV6A 3NEIA 3HH1A 4MV0A 4MUXA 2E08A 3LMMA 2E4NA 3UV7A 3UTDA 1CBFA 2EK3A 3UWMA 3KE9A 1WDEA 1WNGA 2DXXA 2PB6A 2EJJA 2ENIA 3DNFA 3T0GA 4H4DA 2DV7A 2CBFA 2NPNA 2YBQA 3SZLA 2E0KA 1VCEA 2PCGA 2PB4A 2KYYA 4H4EA 3ZGLA 2ELEA 2E15A 2QBUA 1VHVA 2DV3A 2BB3A 2E17A 2DXVA 2EN5A 2OWKA 3F7TA
chains in the Genus database with same CATH topology
2EMUA 2DSGA 3KE8A 4N7BA 3ZGNA 2EEQA 2PCAA 2ZVBA 2DEKA 3UTCA 2ZVCA 3SZOA 3NDCA 3KEMA 2PCIA 2OWVA 3NUTA 2HUVA 1V9AA 2DXWA 3FQ6A 3KWPA 2OWUA 3I4TA 2E8HA 2OWGA 2EL0A 2HUQA 2E0NA 1PJTA 3KELA 2DV5A 2P9DA 4H4CA 2P6LA 1PJQA 2EGBA 3UV3A 2DV4A 2PCMA 2EMRA 2EH4A 2EKAA 3KEFA 2EK4A 2P5FA 1PJSA 2EHLA 2ED3A 1S4DA 2E8RA 2EL3A 1VA0A 2DSIA 2E8QA 2P6KA 2P6DA 4E16A 2Z6RA 2E4RA 4EB3A 5HW4A 2E8SA 2EK2A 2EGSA 2EJZA 2EH5A 2OWFA 2PCKA 3SZUA 2EK7A 3ND1A 2YBOA 1VE2A 3TIXB 2EL1A 2DSHA 2E07A 3URKA 2EHCA 2P2XA 1WYZA 2ED5A 2HR8A 2HUTA 2PB5A 2E7RA 2P6IA 2P5CA 2HUXA 3T0FA 3FFYA 2EJKA 2E16A 2EGLA 4MV5A 4MUYA 2PCHA 2ELDA 2EH2A 2EL2A 3UV6A 3NEIA 3HH1A 4MV0A 4MUXA 2E08A 3LMMA 2E4NA 3UV7A 3UTDA 1CBFA 2EK3A 3UWMA 3KE9A 1WDEA 1WNGA 2DXXA 2PB6A 2EJJA 2ENIA 3DNFA 3T0GA 4H4DA 2DV7A 2CBFA 2NPNA 2YBQA 3SZLA 2E0KA 1VCEA 2PCGA 2PB4A 2KYYA 4H4EA 3ZGLA 2ELEA 2E15A 2QBUA 1VHVA 2DV3A 2BB3A 2E17A 2DXVA 2EN5A 2OWKA 3F7TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EMU A;  2DSG A;  2EEQ A;  2PCA A;  2ZVB A;  2DEK A;  2ZVC A;  3NDC A;  2PCI A;  2OWV A;  3NUT A;  2HUV A;  1V9A A;  2DXW A;  3FQ6 A;  3KWP A;  2OWU A;  3I4T A;  2E8H A;  2OWG A;  2EL0 A;  2HUQ A;  2E0N A;  1PJT A;  2DV5 A;  2P9D A;  2P6L A;  1PJQ A;  2EGB A;  2DV4 A;  2PCM A;  2EMR A;  2EH4 A;  2EKA A;  2EK4 A;  2P5F A;  1PJS A;  2EHL A;  2ED3 A;  1S4D A;  2E8R A;  2EL3 A;  1VA0 A;  2DSI A;  2E8Q A;  2P6K A;  2P6D A;  4E16 A;  2Z6R A;  2E4R A;  5HW4 A;  2E8S A;  2EK2 A;  2EGS A;  2EJZ A;  2EH5 A;  2OWF A;  2PCK A;  2EK7 A;  3ND1 A;  2YBO A;  1VE2 A;  2EL1 A;  2DSH A;  2E07 A;  2EHC A;  2P2X A;  1WYZ A;  2ED5 A;  2HR8 A;  2HUT A;  2PB5 A;  2E7R A;  2P6I A;  2P5C A;  2HUX A;  3FFY A;  2EJK A;  2E16 A;  2EGL A;  2PCH A;  2ELD A;  2EH2 A;  2EL2 A;  3NEI A;  3HH1 A;  2E08 A;  2E4N A;  1CBF A;  2EK3 A;  1WDE A;  1WNG A;  2DXX A;  2PB6 A;  2EJJ A;  2ENI A;  2DV7 A;  2CBF A;  2NPN A;  2YBQ A;  2E0K A;  1VCE A;  2PCG A;  2PB4 A;  2ELE A;  2E15 A;  2QBU A;  1VHV A;  2DV3 A;  2BB3 A;  2E17 A;  2DXV A;  2EN5 A;  2OWK A; 
#chains in the Genus database with same CATH topology
 2EMU A;  2DSG A;  3KE8 A;  4N7B A;  3ZGN A;  2EEQ A;  2PCA A;  2ZVB A;  2DEK A;  3UTC A;  2ZVC A;  3SZO A;  3NDC A;  3KEM A;  2PCI A;  2OWV A;  3NUT A;  2HUV A;  1V9A A;  2DXW A;  3FQ6 A;  3KWP A;  2OWU A;  3I4T A;  2E8H A;  2OWG A;  2EL0 A;  2HUQ A;  2E0N A;  1PJT A;  3KEL A;  2DV5 A;  2P9D A;  4H4C A;  2P6L A;  1PJQ A;  2EGB A;  3UV3 A;  2DV4 A;  2PCM A;  2EMR A;  2EH4 A;  2EKA A;  3KEF A;  2EK4 A;  2P5F A;  1PJS A;  2EHL A;  2ED3 A;  1S4D A;  2E8R A;  2EL3 A;  1VA0 A;  2DSI A;  2E8Q A;  2P6K A;  2P6D A;  4E16 A;  2Z6R A;  2E4R A;  4EB3 A;  5HW4 A;  2E8S A;  2EK2 A;  2EGS A;  2EJZ A;  2EH5 A;  2OWF A;  2PCK A;  3SZU A;  2EK7 A;  3ND1 A;  2YBO A;  1VE2 A;  3TIX B;  2EL1 A;  2DSH A;  2E07 A;  3URK A;  2EHC A;  2P2X A;  1WYZ A;  2ED5 A;  2HR8 A;  2HUT A;  2PB5 A;  2E7R A;  2P6I A;  2P5C A;  2HUX A;  3T0F A;  3FFY A;  2EJK A;  2E16 A;  2EGL A;  4MV5 A;  4MUY A;  2PCH A;  2ELD A;  2EH2 A;  2EL2 A;  3UV6 A;  3NEI A;  3HH1 A;  4MV0 A;  4MUX A;  2E08 A;  3LMM A;  2E4N A;  3UV7 A;  3UTD A;  1CBF A;  2EK3 A;  3UWM A;  3KE9 A;  1WDE A;  1WNG A;  2DXX A;  2PB6 A;  2EJJ A;  2ENI A;  3DNF A;  3T0G A;  4H4D A;  2DV7 A;  2CBF A;  2NPN A;  2YBQ A;  3SZL A;  2E0K A;  1VCE A;  2PCG A;  2PB4 A;  2KYY A;  4H4E A;  3ZGL A;  2ELE A;  2E15 A;  2QBU A;  1VHV A;  2DV3 A;  2BB3 A;  2E17 A;  2DXV A;  2EN5 A;  2OWK A;  3F7T A; 
#chains in the Genus database with same CATH homology
 2EMU A;  2DSG A;  3KE8 A;  4N7B A;  3ZGN A;  2EEQ A;  2PCA A;  2ZVB A;  2DEK A;  3UTC A;  2ZVC A;  3SZO A;  3NDC A;  3KEM A;  2PCI A;  2OWV A;  3NUT A;  2HUV A;  1V9A A;  2DXW A;  3FQ6 A;  3KWP A;  2OWU A;  3I4T A;  2E8H A;  2OWG A;  2EL0 A;  2HUQ A;  2E0N A;  1PJT A;  3KEL A;  2DV5 A;  2P9D A;  4H4C A;  2P6L A;  1PJQ A;  2EGB A;  3UV3 A;  2DV4 A;  2PCM A;  2EMR A;  2EH4 A;  2EKA A;  3KEF A;  2EK4 A;  2P5F A;  1PJS A;  2EHL A;  2ED3 A;  1S4D A;  2E8R A;  2EL3 A;  1VA0 A;  2DSI A;  2E8Q A;  2P6K A;  2P6D A;  4E16 A;  2Z6R A;  2E4R A;  4EB3 A;  5HW4 A;  2E8S A;  2EK2 A;  2EGS A;  2EJZ A;  2EH5 A;  2OWF A;  2PCK A;  3SZU A;  2EK7 A;  3ND1 A;  2YBO A;  1VE2 A;  3TIX B;  2EL1 A;  2DSH A;  2E07 A;  3URK A;  2EHC A;  2P2X A;  1WYZ A;  2ED5 A;  2HR8 A;  2HUT A;  2PB5 A;  2E7R A;  2P6I A;  2P5C A;  2HUX A;  3T0F A;  3FFY A;  2EJK A;  2E16 A;  2EGL A;  4MV5 A;  4MUY A;  2PCH A;  2ELD A;  2EH2 A;  2EL2 A;  3UV6 A;  3NEI A;  3HH1 A;  4MV0 A;  4MUX A;  2E08 A;  3LMM A;  2E4N A;  3UV7 A;  3UTD A;  1CBF A;  2EK3 A;  3UWM A;  3KE9 A;  1WDE A;  1WNG A;  2DXX A;  2PB6 A;  2EJJ A;  2ENI A;  3DNF A;  3T0G A;  4H4D A;  2DV7 A;  2CBF A;  2NPN A;  2YBQ A;  3SZL A;  2E0K A;  1VCE A;  2PCG A;  2PB4 A;  2KYY A;  4H4E A;  3ZGL A;  2ELE A;  2E15 A;  2QBU A;  1VHV A;  2DV3 A;  2BB3 A;  2E17 A;  2DXV A;  2EN5 A;  2OWK A;  3F7T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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