2EGVA

Crystal structure of rrna methyltransferase with sam ligand
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
229
structure length
229
Chain Sequence
b'MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UPF0088 protein aq_165
publication title Crystal structure of rRNA methyltransferase with SAM ligand
rcsb
source organism Aquifex aeolicus
molecule tags Rna methyltransferase
total genus 72
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egvA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egvA02
4E8BA 4YVHA 4YQBA 4YQDA 1X7OA 1Z85A 4RG1A 3KY7A 5GMBA 3L8UA 3IEFA 4X3LA 4YPXA 3BBHA 2EGWA 4YQTA 4YPWA 4YQIA 4JALA 2I6DA 3KW2A 3E5YA 1UAKA 1OY5A 3IC6A 1NS5A 3DCMX 4YVIA 4YQNA 3BBDA 3AIAA 3OINA 2Z0YA 4X3MA 1O6DA 4YVJA 4YVGA 4H3ZA 4YQ9A 4KGNA 2HA8A 2QWVA 4MCCA 4H3YA 3N4JA 1IPAA 3BBEA 5CO4A 1UAMA 3NK6A 4XBOA 1VHKA 2YY8A 1X7PA 1NXZA 4CNDA 4J3CA 4PZKA 4YQLA 1MXIA 2O3AA 3OIJA 3O7BA 4YQ2A 5GMCA 4JAKA 4IG6A 1GZ0A 1V2XA 4L69A 2CX8A 4YQ3A 3KNUA 4YQSA 4YPYA 1ZJRA 1V6ZA 4YQ7A 1K3RA 1P9PA 4YPZA 4YQOA 4YQPA 4CNGA 3ILKA 4CNFA 2V3JA 1UALA 4YQ0A 3QUVA 1J85A 4YQ4A 4KDZA 1UAJA 4YQQA 5GM8A 2V3KA 4YQ5A 3AI9X 3KTYA 3OIIA 2QMMA 4YQRA 3AXZA 2EGVA 3N4KA 3ONPA 4YQAA 1VH0A 4YQCA 2NWAA 3GYQA 4YQ6A 4CNEA 1TO0A 4YQJA 4MCDA 4YQKA 4YQGA 4YQ8A 3NK7A 4FAKA 4YVKA 1VHYA 4YQ1A 5FAIA 5D9FA 4MCBA
chains in the Genus database with same CATH superfamily
4E8BA 4YVHA 3J7ZV 4YQBA 5DM7S 4YQDA 2AE0X 1X7OA 1Z85A 3CF5S 3KY7A 4RG1A 5GMBA 3L8UA 2ZJRS 3IEFA 4X3LA 4YPXA 3BBHA 2RD2A 2EGWA 4YQTA 4YPWA 4YQIA 4JALA 5JVHS 4IO9S 2I6DA 2ZJQS 3KW2A 1UDXA 5GAHW 1QRUA 3E5YA 4JXXA 2GAEA 4MCBA 5DM6S 1UAKA 1OY5A 2PI8A 3IC6A 1NS5A 3DCMX 4YVIA 4JWGA 1EXDA 1O0CA 4YQNA 5GAEW 4H3SA 3BBDA 3AIAA 3OINA 3CZBA 2Z0YA 4X3MA 2ZJPS 1FEUA 4JYZA 1O6DA 4YVJA 2G6GA 3PIPS 1D6KA 3W2WB 5BNZA 4YVGA 4H3ZA 4YQ9A 4KGNA 2HA8A 2QWVA 1QTQA 4WFNS 4IOAS 4MCCA 4H3YA 5JVGS 1DFUP 2G5DA 2PICA 1IPAA 3BBEA 5CO4A 1UAMA 3NK6A 4XBOA 1EUQA 1VHKA 4JXZA 2YY8A 2PJJA 4WF9S 4UY88 1X7PA 1NXZA 4CNDA 4J3CA 4PZKA 4YQLA 1MXIA 2O3AA 3OIJA 1B75A 3O7BA 3AIIA 4YQ2A 5GMCA 4JAKA 2PNWA 4IG6A 1GZ0A 2HZ7A 1V2XA 4L69A 4FMWA 1NYLA 2CX8A 1EUYA 4YQ3A 1GTRA 4P2BA 3KNUA 4YQSA 4YPYA 1ZJRA 3W2VB 1V6ZA 1O0BA 4JWFA 1K3RA 4YQ7A 3PIOS 1P9PA 4YPZA 5GADW 4YQOA 4YQPA 4WCES 4CNGA 3ILKA 4JWHA 1QRTA 1UALA 2V3JA 1ZJWA 4CNFA 4YQ0A 1J85A 3QUVA 4YQ4A 4U67S 4KDZA 1UAJA 4YQQA 5GM8A 2V3KA 4YQ5A 3AI9X 3KTYA 3OIIA 2RE8A 4IOCS 2QMMA 4WFAS 3AXZA 4YQRA 4V194 4WFBS 5IZNA 4JWJA 2EGVA 3N4KA 3ONPA 4YQAA 1VH0A 4YQCA 2NWAA 4H4KA 3GYQA 4YQ6A 4CNEA 1TO0A 4YQJA 3X1LB 4MCDA 4YQKA 1GTSA 4YQGA 4YQ8A 3NK7A 4FAKA 4YVKA 5GAGW 1VHYA 4YQ1A 5FAIA 3DLLS 5D9FA 3N4JA 1QRSA 5HL7S
chains in the Genus database with same CATH topology
4E8BA 4YVHA 4YQBA 4YQDA 1X7OA 1Z85A 3KY7A 4RG1A 5GMBA 3L8UA 3IEFA 4X3LA 4YPXA 3BBHA 2EGWA 4YQTA 4YPWA 4YQIA 4JALA 2I6DA 3KW2A 3E5YA 4MCBA 1UAKA 1OY5A 3IC6A 1NS5A 3DCMX 4YVIA 4JWGA 4YQNA 3BBDA 3AIAA 3OINA 2Z0YA 4X3MA 1O6DA 4YVJA 4YVGA 4H3ZA 4YQ9A 4KGNA 2HA8A 2QWVA 4MCCA 4H3YA 1IPAA 3BBEA 5CO4A 1UAMA 3NK6A 4XBOA 1VHKA 2YY8A 1X7PA 1NXZA 4CNDA 4J3CA 4PZKA 4YQLA 1MXIA 2O3AA 3OIJA 3O7BA 4YQ2A 5GMCA 4JAKA 4IG6A 1GZ0A 1V2XA 4L69A 4FMWA 2CX8A 4YQ3A 3KNUA 4YQSA 4YPYA 1ZJRA 1V6ZA 4JWFA 4YQ7A 1K3RA 1P9PA 4YPZA 4YQOA 4YQPA 4CNGA 3ILKA 4JWHA 4CNFA 2V3JA 1UALA 4YQ0A 3QUVA 1J85A 4YQ4A 4KDZA 1UAJA 4YQQA 5GM8A 2V3KA 4YQ5A 3AI9X 3KTYA 3OIIA 2QMMA 4YQRA 3AXZA 4JWJA 2EGVA 3N4KA 3ONPA 4YQAA 1VH0A 4YQCA 2NWAA 3GYQA 4YQ6A 4CNEA 1TO0A 4YQJA 4MCDA 4YQKA 4YQGA 4YQ8A 3NK7A 4FAKA 4YVKA 1VHYA 4YQ1A 5FAIA 5D9FA 3N4JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E8B A;  4YVH A;  4YQB A;  4YQD A;  1X7O A;  1Z85 A;  4RG1 A;  3KY7 A;  5GMB A;  3L8U A;  3IEF A;  4X3L A;  4YPX A;  3BBH A;  2EGW A;  4YQT A;  4YPW A;  4YQI A;  4JAL A;  2I6D A;  3KW2 A;  3E5Y A;  1UAK A;  1OY5 A;  3IC6 A;  1NS5 A;  3DCM X;  4YVI A;  4YQN A;  3BBD A;  3AIA A;  3OIN A;  2Z0Y A;  4X3M A;  1O6D A;  4YVJ A;  4YVG A;  4H3Z A;  4YQ9 A;  4KGN A;  2HA8 A;  2QWV A;  4MCC A;  4H3Y A;  3N4J A;  1IPA A;  3BBE A;  5CO4 A;  1UAM A;  3NK6 A;  4XBO A;  1VHK A;  2YY8 A;  1X7P A;  1NXZ A;  4CND A;  4J3C A;  4PZK A;  4YQL A;  1MXI A;  2O3A A;  3OIJ A;  3O7B A;  4YQ2 A;  5GMC A;  4JAK A;  4IG6 A;  1GZ0 A;  1V2X A;  4L69 A;  2CX8 A;  4YQ3 A;  3KNU A;  4YQS A;  4YPY A;  1ZJR A;  1V6Z A;  4YQ7 A;  1K3R A;  1P9P A;  4YPZ A;  4YQO A;  4YQP A;  4CNG A;  3ILK A;  4CNF A;  2V3J A;  1UAL A;  4YQ0 A;  3QUV A;  1J85 A;  4YQ4 A;  4KDZ A;  1UAJ A;  4YQQ A;  5GM8 A;  2V3K A;  4YQ5 A;  3AI9 X;  3KTY A;  3OII A;  2QMM A;  4YQR A;  3AXZ A;  2EGV A;  3N4K A;  3ONP A;  4YQA A;  1VH0 A;  4YQC A;  2NWA A;  3GYQ A;  4YQ6 A;  4CNE A;  1TO0 A;  4YQJ A;  4MCD A;  4YQK A;  4YQG A;  4YQ8 A;  3NK7 A;  4FAK A;  4YVK A;  1VHY A;  4YQ1 A;  5FAI A;  5D9F A;  4MCB A; 
#chains in the Genus database with same CATH topology
 4E8B A;  4YVH A;  3J7Z V;  4YQB A;  5DM7 S;  4YQD A;  2AE0 X;  1X7O A;  1Z85 A;  3CF5 S;  3KY7 A;  4RG1 A;  5GMB A;  3L8U A;  2ZJR S;  3IEF A;  4X3L A;  4YPX A;  3BBH A;  2RD2 A;  2EGW A;  4YQT A;  4YPW A;  4YQI A;  4JAL A;  5JVH S;  4IO9 S;  2I6D A;  2ZJQ S;  3KW2 A;  1UDX A;  5GAH W;  1QRU A;  3E5Y A;  4JXX A;  2GAE A;  4MCB A;  5DM6 S;  1UAK A;  1OY5 A;  2PI8 A;  3IC6 A;  1NS5 A;  3DCM X;  4YVI A;  4JWG A;  1EXD A;  1O0C A;  4YQN A;  5GAE W;  4H3S A;  3BBD A;  3AIA A;  3OIN A;  3CZB A;  2Z0Y A;  4X3M A;  2ZJP S;  1FEU A;  4JYZ A;  1O6D A;  4YVJ A;  2G6G A;  3PIP S;  1D6K A;  3W2W B;  5BNZ A;  4YVG A;  4H3Z A;  4YQ9 A;  4KGN A;  2HA8 A;  2QWV A;  1QTQ A;  4WFN S;  4IOA S;  4MCC A;  4H3Y A;  5JVG S;  1DFU P;  2G5D A;  2PIC A;  1IPA A;  3BBE A;  5CO4 A;  1UAM A;  3NK6 A;  4XBO A;  1EUQ A;  1VHK A;  4JXZ A;  2YY8 A;  2PJJ A;  4WF9 S;  4UY8 8;  1X7P A;  1NXZ A;  4CND A;  4J3C A;  4PZK A;  4YQL A;  1MXI A;  2O3A A;  3OIJ A;  1B75 A;  3O7B A;  3AII A;  4YQ2 A;  5GMC A;  4JAK A;  2PNW A;  4IG6 A;  1GZ0 A;  2HZ7 A;  1V2X A;  4L69 A;  4FMW A;  1NYL A;  2CX8 A;  1EUY A;  4YQ3 A;  1GTR A;  4P2B A;  3KNU A;  4YQS A;  4YPY A;  1ZJR A;  3W2V B;  1V6Z A;  1O0B A;  4JWF A;  1K3R A;  4YQ7 A;  3PIO S;  1P9P A;  4YPZ A;  5GAD W;  4YQO A;  4YQP A;  4WCE S;  4CNG A;  3ILK A;  4JWH A;  1QRT A;  1UAL A;  2V3J A;  1ZJW A;  4CNF A;  4YQ0 A;  1J85 A;  3QUV A;  4YQ4 A;  4U67 S;  4KDZ A;  1UAJ A;  4YQQ A;  5GM8 A;  2V3K A;  4YQ5 A;  3AI9 X;  3KTY A;  3OII A;  2RE8 A;  4IOC S;  2QMM A;  4WFA S;  3AXZ A;  4YQR A;  4V19 4;  4WFB S;  5IZN A;  4JWJ A;  2EGV A;  3N4K A;  3ONP A;  4YQA A;  1VH0 A;  4YQC A;  2NWA A;  4H4K A;  3GYQ A;  4YQ6 A;  4CNE A;  1TO0 A;  4YQJ A;  3X1L B;  4MCD A;  4YQK A;  1GTS A;  4YQG A;  4YQ8 A;  3NK7 A;  4FAK A;  4YVK A;  5GAG W;  1VHY A;  4YQ1 A;  5FAI A;  3DLL S;  5D9F A;  3N4J A;  1QRS A;  5HL7 S; 
#chains in the Genus database with same CATH homology
 4E8B A;  4YVH A;  4YQB A;  4YQD A;  1X7O A;  1Z85 A;  3KY7 A;  4RG1 A;  5GMB A;  3L8U A;  3IEF A;  4X3L A;  4YPX A;  3BBH A;  2EGW A;  4YQT A;  4YPW A;  4YQI A;  4JAL A;  2I6D A;  3KW2 A;  3E5Y A;  4MCB A;  1UAK A;  1OY5 A;  3IC6 A;  1NS5 A;  3DCM X;  4YVI A;  4JWG A;  4YQN A;  3BBD A;  3AIA A;  3OIN A;  2Z0Y A;  4X3M A;  1O6D A;  4YVJ A;  4YVG A;  4H3Z A;  4YQ9 A;  4KGN A;  2HA8 A;  2QWV A;  4MCC A;  4H3Y A;  1IPA A;  3BBE A;  5CO4 A;  1UAM A;  3NK6 A;  4XBO A;  1VHK A;  2YY8 A;  1X7P A;  1NXZ A;  4CND A;  4J3C A;  4PZK A;  4YQL A;  1MXI A;  2O3A A;  3OIJ A;  3O7B A;  4YQ2 A;  5GMC A;  4JAK A;  4IG6 A;  1GZ0 A;  1V2X A;  4L69 A;  4FMW A;  2CX8 A;  4YQ3 A;  3KNU A;  4YQS A;  4YPY A;  1ZJR A;  1V6Z A;  4JWF A;  4YQ7 A;  1K3R A;  1P9P A;  4YPZ A;  4YQO A;  4YQP A;  4CNG A;  3ILK A;  4JWH A;  4CNF A;  2V3J A;  1UAL A;  4YQ0 A;  3QUV A;  1J85 A;  4YQ4 A;  4KDZ A;  1UAJ A;  4YQQ A;  5GM8 A;  2V3K A;  4YQ5 A;  3AI9 X;  3KTY A;  3OII A;  2QMM A;  4YQR A;  3AXZ A;  4JWJ A;  2EGV A;  3N4K A;  3ONP A;  4YQA A;  1VH0 A;  4YQC A;  2NWA A;  3GYQ A;  4YQ6 A;  4CNE A;  1TO0 A;  4YQJ A;  4MCD A;  4YQK A;  4YQG A;  4YQ8 A;  3NK7 A;  4FAK A;  4YVK A;  1VHY A;  4YQ1 A;  5FAI A;  5D9F A;  3N4J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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