2EGVA

Crystal structure of rrna methyltransferase with sam ligand
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
229
structure length
229
Chain Sequence
MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of rRNA methyltransferase with SAM ligand
rcsb
source organism Aquifex aeolicus
molecule tags Rna methyltransferase
molecule keywords UPF0088 protein aq_165
total genus 72
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egvA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egvA02
5GMBA 4CNGA 3N4KA 4YQNA 3O7BA 3KW2A 1VHKA 1J85A 3OINA 4RG1A 4H3ZA 3N4JA 4YQQA 2V3JA 3GYQA 4YQ3A 3ONPA 4YQ5A 1X7OA 2HA8A 4YVJA 4YQ8A 1Z85A 2NWAA 4YQPA 3QUVA 4YQ6A 1P9PA 3BBHA 4CNEA 4YQKA 4YPXA 4PZKA 5GM8A 3E5YA 3KTYA 1TO0A 3AI9X 2O3AA 3AIAA 4YVIA 2YY8A 4J3CA 4KDZA 4E8BA 4YQLA 3NK6A 4YQRA 4CNFA 4YVKA 4YQBA 3AXZA 4YQCA 1NXZA 4FAKA 1UAKA 4YQJA 4XBOA 1MXIA 4X3MA 4MCCA 4YPWA 2EGWA 2I6DA 1VHYA 4YQSA 3OIIA 5GMCA 4YPZA 4KGNA 3BBDA 1UAMA 5CO4A 4YQ1A 4IG6A 4JAKA 1IPAA 4YQ2A 5D9FA 3IC6A 4L69A 2CX8A 4X3LA 4JALA 1UALA 5FAIA 4MCBA 1V6ZA 4YVGA 1UAJA 4YQOA 4YVHA 2EGVA 1O6DA 3OIJA 3DCMX 2QMMA 2Z0YA 3KY7A 3KNUA 2QWVA 4YQ7A 1NS5A 3NK7A 1ZJRA 4MCDA 1X7PA 4YQ9A 1K3RA 3ILKA 4H3YA 4YQ0A 1V2XA 1VH0A 3BBEA 4CNDA 4YQAA 3L8UA 3IEFA 4YPYA 4YQDA 4YQTA 1GZ0A 4YQ4A 4YQGA 1OY5A 4YQIA 2V3KA
chains in the Genus database with same CATH superfamily
5GMBA 4CNGA 3PIPS 3W2WB 4P2BA 3N4KA 4YQNA 3O7BA 3KW2A 1VHKA 5BNZA 1J85A 3OINA 4JXXA 1O0CA 1EXDA 4RG1A 5GAHW 4H3ZA 3N4JA 4YQQA 2V3JA 3GYQA 4YQ3A 3ONPA 4YQ5A 4H3SA 1X7OA 2HA8A 4YVJA 4YQ8A 1Z85A 2NWAA 2PJJA 2ZJQS 3QUVA 4YQ6A 4YQPA 1P9PA 3BBHA 4CNEA 4YQKA 1QRSA 5GAGW 4JWHA 4WFNS 4YPXA 5JVGS 4PZKA 5GAEW 5GM8A 3E5YA 3KTYA 1TO0A 5IZNA 4JYZA 3AI9X 2ZJPS 2O3AA 3PIOS 3AIAA 4WF9S 4YVIA 2YY8A 4JWGA 4J3CA 4KDZA 2G5DA 1GTSA 4E8BA 4YQLA 3NK6A 4YQRA 1GTRA 4CNFA 3DLLS 5DM7S 4YVKA 4YQBA 3AXZA 4YQCA 4IOAS 1FEUA 1DFUP 1NXZA 1UDXA 4FAKA 1UAKA 4U67S 4YQJA 1NYLA 4XBOA 1MXIA 4X3MA 4MCCA 4YPWA 2EGWA 2G6GA 4JXZA 2I6DA 2PI8A 4IO9S 1VHYA 4JWJA 4YQSA 4IOCS 3OIIA 5GMCA 2HZ7A 2GAEA 4YPZA 5GADW 4KGNA 3CZBA 3BBDA 2RE8A 1UAMA 5CO4A 4YQ1A 4IG6A 3CF5S 4JAKA 1IPAA 4YQ2A 4JWFA 5D9FA 3IC6A 4L69A 5DM6S 2CX8A 3W2VB 4X3LA 4JALA 4WCES 1UALA 5FAIA 4MCBA 3X1LB 1V6ZA 4YVGA 1UAJA 4YQOA 4YVHA 2EGVA 1O6DA 4UY88 3OIJA 2RD2A 2QMMA 3DCMX 1QRTA 2Z0YA 1EUQA 3KY7A 3KNUA 2QWVA 4YQ7A 4H4KA 1NS5A 5HL7S 3NK7A 1ZJRA 1D6KA 4V194 4MCDA 3J7ZV 2PICA 4FMWA 1X7PA 3AIIA 4YQ9A 4WFBS 1ZJWA 1K3RA 3ILKA 4H3YA 1EUYA 4YQ0A 1V2XA 2AE0X 1VH0A 3BBEA 4CNDA 1O0BA 4YQAA 2PNWA 3L8UA 1QRUA 3IEFA 4YPYA 4YQDA 4YQTA 1B75A 1GZ0A 5JVHS 4YQ4A 4YQGA 1OY5A 4YQIA 1QTQA 2V3KA 4WFAS 2ZJRS
chains in the Genus database with same CATH topology
5GMBA 4CNGA 3N4KA 4YQNA 3O7BA 3KW2A 1VHKA 1J85A 3OINA 4RG1A 4H3ZA 3N4JA 4YQQA 2V3JA 3GYQA 4YQ3A 3ONPA 4YQ5A 1X7OA 2HA8A 4YVJA 4YQ8A 1Z85A 2NWAA 4YQPA 3QUVA 4YQ6A 1P9PA 3BBHA 4CNEA 4YQKA 4JWHA 4YPXA 4PZKA 5GM8A 3E5YA 3KTYA 1TO0A 3AI9X 2O3AA 3AIAA 4YVIA 2YY8A 4JWGA 4J3CA 4KDZA 4E8BA 4YQLA 3NK6A 4YQRA 4CNFA 4YVKA 4YQBA 3AXZA 4YQCA 1NXZA 4FAKA 1UAKA 4YQJA 4XBOA 1MXIA 4X3MA 4MCCA 4YPWA 2EGWA 2I6DA 1VHYA 4JWJA 4YQSA 3OIIA 5GMCA 4YPZA 4KGNA 3BBDA 1UAMA 5CO4A 4YQ1A 4IG6A 4JAKA 1IPAA 4YQ2A 4JWFA 5D9FA 3IC6A 4L69A 2CX8A 4X3LA 4JALA 1UALA 5FAIA 4MCBA 1V6ZA 4YVGA 1UAJA 4YQOA 4YVHA 2EGVA 1O6DA 3OIJA 3DCMX 2QMMA 2Z0YA 3KY7A 3KNUA 2QWVA 4YQ7A 1NS5A 3NK7A 1ZJRA 4MCDA 4FMWA 1X7PA 4YQ9A 1K3RA 3ILKA 4H3YA 4YQ0A 1V2XA 1VH0A 3BBEA 4CNDA 4YQAA 3L8UA 3IEFA 4YPYA 4YQDA 4YQTA 1GZ0A 4YQ4A 4YQGA 1OY5A 4YQIA 2V3KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GMB A;  4CNG A;  3N4K A;  4YQN A;  3O7B A;  3KW2 A;  1VHK A;  1J85 A;  3OIN A;  4RG1 A;  4H3Z A;  3N4J A;  4YQQ A;  2V3J A;  3GYQ A;  4YQ3 A;  3ONP A;  4YQ5 A;  1X7O A;  2HA8 A;  4YVJ A;  4YQ8 A;  1Z85 A;  2NWA A;  4YQP A;  3QUV A;  4YQ6 A;  1P9P A;  3BBH A;  4CNE A;  4YQK A;  4YPX A;  4PZK A;  5GM8 A;  3E5Y A;  3KTY A;  1TO0 A;  3AI9 X;  2O3A A;  3AIA A;  4YVI A;  2YY8 A;  4J3C A;  4KDZ A;  4E8B A;  4YQL A;  3NK6 A;  4YQR A;  4CNF A;  4YVK A;  4YQB A;  3AXZ A;  4YQC A;  1NXZ A;  4FAK A;  1UAK A;  4YQJ A;  4XBO A;  1MXI A;  4X3M A;  4MCC A;  4YPW A;  2EGW A;  2I6D A;  1VHY A;  4YQS A;  3OII A;  5GMC A;  4YPZ A;  4KGN A;  3BBD A;  1UAM A;  5CO4 A;  4YQ1 A;  4IG6 A;  4JAK A;  1IPA A;  4YQ2 A;  5D9F A;  3IC6 A;  4L69 A;  2CX8 A;  4X3L A;  4JAL A;  1UAL A;  5FAI A;  4MCB A;  1V6Z A;  4YVG A;  1UAJ A;  4YQO A;  4YVH A;  2EGV A;  1O6D A;  3OIJ A;  3DCM X;  2QMM A;  2Z0Y A;  3KY7 A;  3KNU A;  2QWV A;  4YQ7 A;  1NS5 A;  3NK7 A;  1ZJR A;  4MCD A;  1X7P A;  4YQ9 A;  1K3R A;  3ILK A;  4H3Y A;  4YQ0 A;  1V2X A;  1VH0 A;  3BBE A;  4CND A;  4YQA A;  3L8U A;  3IEF A;  4YPY A;  4YQD A;  4YQT A;  1GZ0 A;  4YQ4 A;  4YQG A;  1OY5 A;  4YQI A;  2V3K A; 
#chains in the Genus database with same CATH topology
 5GMB A;  4CNG A;  3PIP S;  3W2W B;  4P2B A;  3N4K A;  4YQN A;  3O7B A;  3KW2 A;  1VHK A;  5BNZ A;  1J85 A;  3OIN A;  4JXX A;  1O0C A;  1EXD A;  4RG1 A;  5GAH W;  4H3Z A;  3N4J A;  4YQQ A;  2V3J A;  3GYQ A;  4YQ3 A;  3ONP A;  4YQ5 A;  4H3S A;  1X7O A;  2HA8 A;  4YVJ A;  4YQ8 A;  1Z85 A;  2NWA A;  2PJJ A;  2ZJQ S;  3QUV A;  4YQ6 A;  4YQP A;  1P9P A;  3BBH A;  4CNE A;  4YQK A;  1QRS A;  5GAG W;  4JWH A;  4WFN S;  4YPX A;  5JVG S;  4PZK A;  5GAE W;  5GM8 A;  3E5Y A;  3KTY A;  1TO0 A;  5IZN A;  4JYZ A;  3AI9 X;  2ZJP S;  2O3A A;  3PIO S;  3AIA A;  4WF9 S;  4YVI A;  2YY8 A;  4JWG A;  4J3C A;  4KDZ A;  2G5D A;  1GTS A;  4E8B A;  4YQL A;  3NK6 A;  4YQR A;  1GTR A;  4CNF A;  3DLL S;  5DM7 S;  4YVK A;  4YQB A;  3AXZ A;  4YQC A;  4IOA S;  1FEU A;  1DFU P;  1NXZ A;  1UDX A;  4FAK A;  1UAK A;  4U67 S;  4YQJ A;  1NYL A;  4XBO A;  1MXI A;  4X3M A;  4MCC A;  4YPW A;  2EGW A;  2G6G A;  4JXZ A;  2I6D A;  2PI8 A;  4IO9 S;  1VHY A;  4JWJ A;  4YQS A;  4IOC S;  3OII A;  5GMC A;  2HZ7 A;  2GAE A;  4YPZ A;  5GAD W;  4KGN A;  3CZB A;  3BBD A;  2RE8 A;  1UAM A;  5CO4 A;  4YQ1 A;  4IG6 A;  3CF5 S;  4JAK A;  1IPA A;  4YQ2 A;  4JWF A;  5D9F A;  3IC6 A;  4L69 A;  5DM6 S;  2CX8 A;  3W2V B;  4X3L A;  4JAL A;  4WCE S;  1UAL A;  5FAI A;  4MCB A;  3X1L B;  1V6Z A;  4YVG A;  1UAJ A;  4YQO A;  4YVH A;  2EGV A;  1O6D A;  4UY8 8;  3OIJ A;  2RD2 A;  2QMM A;  3DCM X;  1QRT A;  2Z0Y A;  1EUQ A;  3KY7 A;  3KNU A;  2QWV A;  4YQ7 A;  4H4K A;  1NS5 A;  5HL7 S;  3NK7 A;  1ZJR A;  1D6K A;  4V19 4;  4MCD A;  3J7Z V;  2PIC A;  4FMW A;  1X7P A;  3AII A;  4YQ9 A;  4WFB S;  1ZJW A;  1K3R A;  3ILK A;  4H3Y A;  1EUY A;  4YQ0 A;  1V2X A;  2AE0 X;  1VH0 A;  3BBE A;  4CND A;  1O0B A;  4YQA A;  2PNW A;  3L8U A;  1QRU A;  3IEF A;  4YPY A;  4YQD A;  4YQT A;  1B75 A;  1GZ0 A;  5JVH S;  4YQ4 A;  4YQG A;  1OY5 A;  4YQI A;  1QTQ A;  2V3K A;  4WFA S;  2ZJR S; 
#chains in the Genus database with same CATH homology
 5GMB A;  4CNG A;  3N4K A;  4YQN A;  3O7B A;  3KW2 A;  1VHK A;  1J85 A;  3OIN A;  4RG1 A;  4H3Z A;  3N4J A;  4YQQ A;  2V3J A;  3GYQ A;  4YQ3 A;  3ONP A;  4YQ5 A;  1X7O A;  2HA8 A;  4YVJ A;  4YQ8 A;  1Z85 A;  2NWA A;  4YQP A;  3QUV A;  4YQ6 A;  1P9P A;  3BBH A;  4CNE A;  4YQK A;  4JWH A;  4YPX A;  4PZK A;  5GM8 A;  3E5Y A;  3KTY A;  1TO0 A;  3AI9 X;  2O3A A;  3AIA A;  4YVI A;  2YY8 A;  4JWG A;  4J3C A;  4KDZ A;  4E8B A;  4YQL A;  3NK6 A;  4YQR A;  4CNF A;  4YVK A;  4YQB A;  3AXZ A;  4YQC A;  1NXZ A;  4FAK A;  1UAK A;  4YQJ A;  4XBO A;  1MXI A;  4X3M A;  4MCC A;  4YPW A;  2EGW A;  2I6D A;  1VHY A;  4JWJ A;  4YQS A;  3OII A;  5GMC A;  4YPZ A;  4KGN A;  3BBD A;  1UAM A;  5CO4 A;  4YQ1 A;  4IG6 A;  4JAK A;  1IPA A;  4YQ2 A;  4JWF A;  5D9F A;  3IC6 A;  4L69 A;  2CX8 A;  4X3L A;  4JAL A;  1UAL A;  5FAI A;  4MCB A;  1V6Z A;  4YVG A;  1UAJ A;  4YQO A;  4YVH A;  2EGV A;  1O6D A;  3OIJ A;  3DCM X;  2QMM A;  2Z0Y A;  3KY7 A;  3KNU A;  2QWV A;  4YQ7 A;  1NS5 A;  3NK7 A;  1ZJR A;  4MCD A;  4FMW A;  1X7P A;  4YQ9 A;  1K3R A;  3ILK A;  4H3Y A;  4YQ0 A;  1V2X A;  1VH0 A;  3BBE A;  4CND A;  4YQA A;  3L8U A;  3IEF A;  4YPY A;  4YQD A;  4YQT A;  1GZ0 A;  4YQ4 A;  4YQG A;  1OY5 A;  4YQI A;  2V3K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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