2EGVA

Crystal structure of rrna methyltransferase with sam ligand
Total Genus 72
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
229
structure length
229
Chain Sequence
MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of rRNA methyltransferase with SAM ligand
rcsb
source organism Aquifex aeolicus
molecule tags Rna methyltransferase
molecule keywords UPF0088 protein aq_165
total genus 72
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egvA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egvA02
4YQCA 4YQ9A 4YQ0A 4YQOA 4KDZA 5GM8A 4L69A 4YQDA 4YQIA 3NK7A 2EGVA 3BBHA 3KTYA 3BBEA 5GMCA 1VH0A 4X3MA 5CO4A 5GMBA 2QWVA 2EGWA 2V3KA 4YQBA 1K3RA 4YQRA 3OIJA 3KW2A 3GYQA 1UAMA 4YQNA 4H3ZA 4MCDA 2I6DA 4JAKA 1IPAA 3OIIA 4YQAA 2HA8A 1Z85A 4YVHA 4CNFA 3KNUA 1VHKA 3O7BA 1MXIA 1P9PA 2YY8A 3ONPA 4MCBA 1J85A 1VHYA 3NK6A 4X3LA 4XBOA 4YVIA 2QMMA 2Z0YA 4YQ3A 3N4JA 1V6ZA 3IC6A 4YPWA 1ZJRA 4YQ4A 4YQGA 4YPZA 3AIAA 4CNGA 4YQJA 3DCMX 4YQ6A 4PZKA 4FAKA 4YQSA 4H3YA 5FAIA 3ILKA 3AI9X 3E5YA 1V2XA 4YVJA 3OINA 2NWAA 4CNDA 3AXZA 4CNEA 1GZ0A 1NXZA 4IG6A 2CX8A 4YQLA 4YVKA 3N4KA 1UAJA 4YQKA 4MCCA 4YQTA 1X7PA 2V3JA 4YQ7A 2O3AA 4KGNA 4YQ5A 1OY5A 4YQQA 1X7OA 4JALA 3KY7A 4RG1A 4YQ1A 1UALA 3QUVA 1TO0A 1UAKA 3IEFA 4YQ2A 3BBDA 4YQPA 4YPYA 4YVGA 5D9FA 4J3CA 4E8BA 1O6DA 4YPXA 1NS5A 4YQ8A 3L8UA
chains in the Genus database with same CATH superfamily
4YQCA 4YQ9A 3X1LB 4WFBS 2RD2A 4YQ0A 5JVHS 1GTSA 4YQOA 4KDZA 2G6GA 4WFNS 4WF9S 5GM8A 2PNWA 4UY88 2PICA 3CF5S 4L69A 4YQDA 4YQIA 3NK7A 2EGVA 2HZ7A 3BBHA 3AIIA 1D6KA 3KTYA 1QRSA 3BBEA 5GMCA 1VH0A 4X3MA 5CO4A 4YQ8A 5GMBA 2QWVA 3W2WB 2EGWA 2V3KA 1ZJWA 4YQBA 1K3RA 2ZJRS 4YQRA 3J7ZV 3OIJA 1EUYA 5GAHW 5DM6S 4JXXA 4JXZA 3W2VB 3KW2A 3GYQA 1UAMA 4YQNA 1B75A 4H3ZA 4MCDA 2I6DA 4JAKA 1IPAA 3OIIA 4YQAA 2HA8A 1Z85A 4YVHA 4CNFA 4JYZA 4H4KA 5GAGW 3KNUA 5GAEW 1NYLA 1VHKA 3O7BA 1MXIA 1P9PA 2YY8A 3ONPA 4IO9S 4MCBA 1J85A 1VHYA 3NK6A 1GTRA 1UDXA 4X3LA 4XBOA 4YVIA 2QMMA 2Z0YA 4YQ3A 3N4JA 1V6ZA 3IC6A 4YPWA 1ZJRA 2PI8A 4YQ4A 4YQGA 4YPZA 3AIAA 2GAEA 4YQJA 4CNGA 5GADW 3DCMX 4YQ6A 4PZKA 4FAKA 4YQSA 4H3SA 1EXDA 5JVGS 4H3YA 4WCES 5FAIA 3ILKA 3AI9X 3E5YA 4V194 1V2XA 4YVJA 5IZNA 3OINA 2AE0X 2NWAA 4CNDA 1O0CA 1QRUA 4P2BA 1DFUP 3AXZA 4CNEA 1GZ0A 1NXZA 4IG6A 4WFAS 1O0BA 1QTQA 1QRTA 2CX8A 4YQLA 4YVKA 3N4KA 4JWJA 5BNZA 4IOCS 3CZBA 4IOAS 1UAJA 4YQKA 4JWGA 4MCCA 4YQTA 1X7PA 2V3JA 4YQ7A 2O3AA 4KGNA 4YQ5A 2PJJA 1OY5A 4YQQA 1X7OA 4JALA 3PIOS 3KY7A 1FEUA 4RG1A 4YQ1A 4FMWA 1UALA 4U67S 3PIPS 2ZJQS 3QUVA 1TO0A 1UAKA 3IEFA 2G5DA 4YQ2A 3BBDA 4YQPA 5DM7S 4YVGA 4YPYA 1EUQA 2RE8A 4JWFA 5D9FA 3DLLS 4J3CA 4JWHA 4E8BA 5HL7S 1O6DA 4YPXA 1NS5A 2ZJPS 3L8UA
chains in the Genus database with same CATH topology
4YQCA 4YQ9A 4YQ0A 4YQOA 4KDZA 5GM8A 4L69A 4YQDA 4YQIA 3NK7A 2EGVA 3BBHA 3KTYA 3BBEA 5GMCA 1VH0A 4X3MA 5CO4A 5GMBA 2QWVA 2EGWA 2V3KA 4YQBA 1K3RA 4YQRA 3OIJA 3KW2A 3GYQA 1UAMA 4YQNA 4H3ZA 4MCDA 2I6DA 4JAKA 1IPAA 3OIIA 4YQAA 2HA8A 1Z85A 4YVHA 4CNFA 3KNUA 1VHKA 3O7BA 1MXIA 1P9PA 2YY8A 3ONPA 4MCBA 1J85A 1VHYA 3NK6A 4X3LA 4XBOA 4YVIA 2QMMA 2Z0YA 4YQ3A 3N4JA 1V6ZA 3IC6A 4YPWA 1ZJRA 4YQ4A 4YQGA 4YPZA 3AIAA 4CNGA 4YQJA 3DCMX 4YQ6A 4PZKA 4FAKA 4YQSA 4H3YA 5FAIA 3ILKA 3AI9X 3E5YA 1V2XA 4YVJA 3OINA 2NWAA 4CNDA 3AXZA 4CNEA 1GZ0A 1NXZA 4IG6A 2CX8A 4YQLA 4YVKA 3N4KA 4JWJA 1UAJA 4YQKA 4JWGA 4MCCA 4YQTA 1X7PA 2V3JA 4YQ7A 2O3AA 4KGNA 4YQ5A 1OY5A 4YQQA 1X7OA 4JALA 3KY7A 4RG1A 4YQ1A 4FMWA 1UALA 3QUVA 1TO0A 1UAKA 3IEFA 4YQ2A 3BBDA 4YQPA 4YPYA 4YVGA 5D9FA 4JWFA 4J3CA 4JWHA 4E8BA 1O6DA 4YPXA 1NS5A 4YQ8A 3L8UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQC A;  4YQ9 A;  4YQ0 A;  4YQO A;  4KDZ A;  5GM8 A;  4L69 A;  4YQD A;  4YQI A;  3NK7 A;  2EGV A;  3BBH A;  3KTY A;  3BBE A;  5GMC A;  1VH0 A;  4X3M A;  5CO4 A;  5GMB A;  2QWV A;  2EGW A;  2V3K A;  4YQB A;  1K3R A;  4YQR A;  3OIJ A;  3KW2 A;  3GYQ A;  1UAM A;  4YQN A;  4H3Z A;  4MCD A;  2I6D A;  4JAK A;  1IPA A;  3OII A;  4YQA A;  2HA8 A;  1Z85 A;  4YVH A;  4CNF A;  3KNU A;  1VHK A;  3O7B A;  1MXI A;  1P9P A;  2YY8 A;  3ONP A;  4MCB A;  1J85 A;  1VHY A;  3NK6 A;  4X3L A;  4XBO A;  4YVI A;  2QMM A;  2Z0Y A;  4YQ3 A;  3N4J A;  1V6Z A;  3IC6 A;  4YPW A;  1ZJR A;  4YQ4 A;  4YQG A;  4YPZ A;  3AIA A;  4CNG A;  4YQJ A;  3DCM X;  4YQ6 A;  4PZK A;  4FAK A;  4YQS A;  4H3Y A;  5FAI A;  3ILK A;  3AI9 X;  3E5Y A;  1V2X A;  4YVJ A;  3OIN A;  2NWA A;  4CND A;  3AXZ A;  4CNE A;  1GZ0 A;  1NXZ A;  4IG6 A;  2CX8 A;  4YQL A;  4YVK A;  3N4K A;  1UAJ A;  4YQK A;  4MCC A;  4YQT A;  1X7P A;  2V3J A;  4YQ7 A;  2O3A A;  4KGN A;  4YQ5 A;  1OY5 A;  4YQQ A;  1X7O A;  4JAL A;  3KY7 A;  4RG1 A;  4YQ1 A;  1UAL A;  3QUV A;  1TO0 A;  1UAK A;  3IEF A;  4YQ2 A;  3BBD A;  4YQP A;  4YPY A;  4YVG A;  5D9F A;  4J3C A;  4E8B A;  1O6D A;  4YPX A;  1NS5 A;  4YQ8 A;  3L8U A; 
#chains in the Genus database with same CATH topology
 4YQC A;  4YQ9 A;  3X1L B;  4WFB S;  2RD2 A;  4YQ0 A;  5JVH S;  1GTS A;  4YQO A;  4KDZ A;  2G6G A;  4WFN S;  4WF9 S;  5GM8 A;  2PNW A;  4UY8 8;  2PIC A;  3CF5 S;  4L69 A;  4YQD A;  4YQI A;  3NK7 A;  2EGV A;  2HZ7 A;  3BBH A;  3AII A;  1D6K A;  3KTY A;  1QRS A;  3BBE A;  5GMC A;  1VH0 A;  4X3M A;  5CO4 A;  4YQ8 A;  5GMB A;  2QWV A;  3W2W B;  2EGW A;  2V3K A;  1ZJW A;  4YQB A;  1K3R A;  2ZJR S;  4YQR A;  3J7Z V;  3OIJ A;  1EUY A;  5GAH W;  5DM6 S;  4JXX A;  4JXZ A;  3W2V B;  3KW2 A;  3GYQ A;  1UAM A;  4YQN A;  1B75 A;  4H3Z A;  4MCD A;  2I6D A;  4JAK A;  1IPA A;  3OII A;  4YQA A;  2HA8 A;  1Z85 A;  4YVH A;  4CNF A;  4JYZ A;  4H4K A;  5GAG W;  3KNU A;  5GAE W;  1NYL A;  1VHK A;  3O7B A;  1MXI A;  1P9P A;  2YY8 A;  3ONP A;  4IO9 S;  4MCB A;  1J85 A;  1VHY A;  3NK6 A;  1GTR A;  1UDX A;  4X3L A;  4XBO A;  4YVI A;  2QMM A;  2Z0Y A;  4YQ3 A;  3N4J A;  1V6Z A;  3IC6 A;  4YPW A;  1ZJR A;  2PI8 A;  4YQ4 A;  4YQG A;  4YPZ A;  3AIA A;  2GAE A;  4YQJ A;  4CNG A;  5GAD W;  3DCM X;  4YQ6 A;  4PZK A;  4FAK A;  4YQS A;  4H3S A;  1EXD A;  5JVG S;  4H3Y A;  4WCE S;  5FAI A;  3ILK A;  3AI9 X;  3E5Y A;  4V19 4;  1V2X A;  4YVJ A;  5IZN A;  3OIN A;  2AE0 X;  2NWA A;  4CND A;  1O0C A;  1QRU A;  4P2B A;  1DFU P;  3AXZ A;  4CNE A;  1GZ0 A;  1NXZ A;  4IG6 A;  4WFA S;  1O0B A;  1QTQ A;  1QRT A;  2CX8 A;  4YQL A;  4YVK A;  3N4K A;  4JWJ A;  5BNZ A;  4IOC S;  3CZB A;  4IOA S;  1UAJ A;  4YQK A;  4JWG A;  4MCC A;  4YQT A;  1X7P A;  2V3J A;  4YQ7 A;  2O3A A;  4KGN A;  4YQ5 A;  2PJJ A;  1OY5 A;  4YQQ A;  1X7O A;  4JAL A;  3PIO S;  3KY7 A;  1FEU A;  4RG1 A;  4YQ1 A;  4FMW A;  1UAL A;  4U67 S;  3PIP S;  2ZJQ S;  3QUV A;  1TO0 A;  1UAK A;  3IEF A;  2G5D A;  4YQ2 A;  3BBD A;  4YQP A;  5DM7 S;  4YVG A;  4YPY A;  1EUQ A;  2RE8 A;  4JWF A;  5D9F A;  3DLL S;  4J3C A;  4JWH A;  4E8B A;  5HL7 S;  1O6D A;  4YPX A;  1NS5 A;  2ZJP S;  3L8U A; 
#chains in the Genus database with same CATH homology
 4YQC A;  4YQ9 A;  4YQ0 A;  4YQO A;  4KDZ A;  5GM8 A;  4L69 A;  4YQD A;  4YQI A;  3NK7 A;  2EGV A;  3BBH A;  3KTY A;  3BBE A;  5GMC A;  1VH0 A;  4X3M A;  5CO4 A;  5GMB A;  2QWV A;  2EGW A;  2V3K A;  4YQB A;  1K3R A;  4YQR A;  3OIJ A;  3KW2 A;  3GYQ A;  1UAM A;  4YQN A;  4H3Z A;  4MCD A;  2I6D A;  4JAK A;  1IPA A;  3OII A;  4YQA A;  2HA8 A;  1Z85 A;  4YVH A;  4CNF A;  3KNU A;  1VHK A;  3O7B A;  1MXI A;  1P9P A;  2YY8 A;  3ONP A;  4MCB A;  1J85 A;  1VHY A;  3NK6 A;  4X3L A;  4XBO A;  4YVI A;  2QMM A;  2Z0Y A;  4YQ3 A;  3N4J A;  1V6Z A;  3IC6 A;  4YPW A;  1ZJR A;  4YQ4 A;  4YQG A;  4YPZ A;  3AIA A;  4CNG A;  4YQJ A;  3DCM X;  4YQ6 A;  4PZK A;  4FAK A;  4YQS A;  4H3Y A;  5FAI A;  3ILK A;  3AI9 X;  3E5Y A;  1V2X A;  4YVJ A;  3OIN A;  2NWA A;  4CND A;  3AXZ A;  4CNE A;  1GZ0 A;  1NXZ A;  4IG6 A;  2CX8 A;  4YQL A;  4YVK A;  3N4K A;  4JWJ A;  1UAJ A;  4YQK A;  4JWG A;  4MCC A;  4YQT A;  1X7P A;  2V3J A;  4YQ7 A;  2O3A A;  4KGN A;  4YQ5 A;  1OY5 A;  4YQQ A;  1X7O A;  4JAL A;  3KY7 A;  4RG1 A;  4YQ1 A;  4FMW A;  1UAL A;  3QUV A;  1TO0 A;  1UAK A;  3IEF A;  4YQ2 A;  3BBD A;  4YQP A;  4YPY A;  4YVG A;  5D9F A;  4JWF A;  4J3C A;  4JWH A;  4E8B A;  1O6D A;  4YPX A;  1NS5 A;  4YQ8 A;  3L8U A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...