2EGVA

Crystal structure of rrna methyltransferase with sam ligand
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
229
structure length
229
Chain Sequence
MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UPF0088 protein aq_165
publication title Crystal structure of rRNA methyltransferase with SAM ligand
rcsb
source organism Aquifex aeolicus
molecule tags Rna methyltransferase
total genus 72
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egvA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egvA02
4PZKA 4YQ9A 4YQ5A 4YPXA 4MCDA 3IC6A 4YQ4A 1UAJA 4KDZA 5FAIA 3E5YA 1P9PA 4YQ8A 2QMMA 2YY8A 1O6DA 4YVKA 2EGVA 3IEFA 5GMBA 4JALA 3NK7A 1X7OA 3KY7A 2I6DA 3BBEA 1GZ0A 3O7BA 3BBDA 4YQKA 3ONPA 4YQ0A 4YPYA 4YQIA 4YQLA 4YQBA 1MXIA 3KW2A 4H3YA 4YQCA 4CNDA 4YVHA 4YVIA 1X7PA 3L8UA 4CNEA 1NS5A 4XBOA 3AXZA 4YPZA 1IPAA 4YQPA 5GMCA 3ILKA 2V3KA 4YQAA 3NK6A 3N4JA 4YQJA 1UAKA 1V6ZA 4X3MA 2CX8A 3DCMX 4YPWA 1VHYA 4FAKA 4YQQA 3BBHA 3OIJA 1V2XA 4YQTA 3AI9X 4L69A 2O3AA 1Z85A 4KGNA 4YQ1A 2EGWA 1TO0A 1VHKA 4CNGA 3OIIA 5GM8A 4YQGA 4JAKA 1NXZA 4YQNA 1K3RA 3OINA 4YQDA 4MCBA 1ZJRA 4H3ZA 1UALA 4X3LA 4YQOA 4YQ2A 2V3JA 1OY5A 3QUVA 4YQ6A 4E8BA 1J85A 4YVJA 2NWAA 3KTYA 1VH0A 4J3CA 5D9FA 4YQSA 2QWVA 2Z0YA 4YQRA 3AIAA 4MCCA 4CNFA 4IG6A 3N4KA 2HA8A 3KNUA 1UAMA 5CO4A 4YQ7A 4YVGA 4RG1A 3GYQA 4YQ3A
chains in the Genus database with same CATH superfamily
5HL7S 4PZKA 4IOCS 4IOAS 4YQ9A 4P2BA 4YQ5A 4YPXA 1O0BA 4MCDA 3IC6A 4YQ4A 1D6KA 1UAJA 4KDZA 4JWJA 4JXZA 5FAIA 3E5YA 4JWFA 4WFAS 1P9PA 4YQ8A 4JYZA 2QMMA 2YY8A 1O6DA 4YVKA 2EGVA 3IEFA 5JVGS 5GMBA 4JALA 3NK7A 1X7OA 3KY7A 1DFUP 5GAHW 2I6DA 3BBEA 4WFNS 1GTSA 1GZ0A 3O7BA 5GAGW 3BBDA 4YQKA 3ONPA 4YQ0A 4YPYA 4YQIA 4YQLA 4YQBA 1MXIA 3KW2A 4H3YA 2G6GA 5JVHS 4YQCA 5GAEW 4CNDA 4YVHA 1QRSA 5DM7S 5GADW 1X7PA 3L8UA 4CNEA 4YVIA 1NS5A 4V194 2ZJRS 4XBOA 3AXZA 4YPZA 1IPAA 4YQPA 5GMCA 3ILKA 2V3KA 3CZBA 4YQAA 1EXDA 3NK6A 4WFBS 3N4JA 4YQJA 5BNZA 1UAKA 1V6ZA 4X3MA 4UY88 2CX8A 4WCES 3DCMX 4YPWA 1VHYA 4FAKA 4YQQA 2G5DA 4H3SA 3BBHA 2RD2A 1QRUA 1V2XA 3OIJA 4YQTA 2ZJQS 3AI9X 4L69A 2GAEA 4JXXA 3X1LB 2O3AA 4IO9S 1Z85A 4KGNA 3AIIA 3W2WB 4YQ1A 2EGWA 1TO0A 1VHKA 2PNWA 4CNGA 3OIIA 5GM8A 4YQGA 3PIPS 1QRTA 4JAKA 1NXZA 4YQNA 1K3RA 3OINA 1FEUA 4YQDA 4JWHA 4MCBA 2RE8A 5DM6S 2ZJPS 2AE0X 4WF9S 1ZJRA 4H3ZA 1UALA 4FMWA 4JWGA 4X3LA 4YQOA 4YQ2A 2V3JA 2PICA 1OY5A 1B75A 3QUVA 1GTRA 1UDXA 4YQ6A 3PIOS 4E8BA 1J85A 2PJJA 4YVJA 1ZJWA 2NWAA 3KTYA 3W2VB 2HZ7A 1O0CA 1VH0A 1NYLA 4J3CA 1EUQA 1QTQA 5D9FA 4YQSA 2QWVA 2Z0YA 4YQRA 3DLLS 3AIAA 4MCCA 4CNFA 1EUYA 4IG6A 3N4KA 2HA8A 3KNUA 1UAMA 5CO4A 4YQ7A 4YVGA 2PI8A 5IZNA 3J7ZV 3CF5S 4RG1A 4H4KA 4U67S 3GYQA 4YQ3A
chains in the Genus database with same CATH topology
4PZKA 4YQ9A 4YQ5A 4YPXA 4MCDA 3IC6A 4YQ4A 1UAJA 4KDZA 4JWJA 5FAIA 3E5YA 4JWFA 1P9PA 4YQ8A 2QMMA 2YY8A 1O6DA 4YVKA 2EGVA 3IEFA 5GMBA 4JALA 3NK7A 1X7OA 3KY7A 2I6DA 3BBEA 1GZ0A 3O7BA 3BBDA 4YQKA 3ONPA 4YQ0A 4YPYA 4YQIA 4YQLA 4YQBA 1MXIA 3KW2A 4H3YA 4YQCA 4CNDA 4YVHA 4YVIA 1X7PA 3L8UA 4CNEA 1NS5A 4XBOA 3AXZA 4YPZA 1IPAA 4YQPA 5GMCA 3ILKA 2V3KA 4YQAA 3NK6A 3N4JA 4YQJA 1UAKA 1V6ZA 4X3MA 2CX8A 3DCMX 4YPWA 1VHYA 4FAKA 4YQQA 3BBHA 3OIJA 1V2XA 4YQTA 3AI9X 4L69A 2O3AA 1Z85A 4KGNA 4YQ1A 2EGWA 1TO0A 1VHKA 4CNGA 3OIIA 5GM8A 4YQGA 4JAKA 1NXZA 4YQNA 1K3RA 3OINA 4YQDA 4JWHA 4MCBA 1ZJRA 4H3ZA 1UALA 4FMWA 4JWGA 4X3LA 4YQOA 4YQ2A 2V3JA 1OY5A 3QUVA 4YQ6A 4E8BA 1J85A 4YVJA 2NWAA 3KTYA 1VH0A 4J3CA 5D9FA 4YQSA 2QWVA 2Z0YA 4YQRA 3AIAA 4MCCA 4CNFA 4IG6A 3N4KA 2HA8A 3KNUA 1UAMA 5CO4A 4YQ7A 4YVGA 4RG1A 3GYQA 4YQ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PZK A;  4YQ9 A;  4YQ5 A;  4YPX A;  4MCD A;  3IC6 A;  4YQ4 A;  1UAJ A;  4KDZ A;  5FAI A;  3E5Y A;  1P9P A;  4YQ8 A;  2QMM A;  2YY8 A;  1O6D A;  4YVK A;  2EGV A;  3IEF A;  5GMB A;  4JAL A;  3NK7 A;  1X7O A;  3KY7 A;  2I6D A;  3BBE A;  1GZ0 A;  3O7B A;  3BBD A;  4YQK A;  3ONP A;  4YQ0 A;  4YPY A;  4YQI A;  4YQL A;  4YQB A;  1MXI A;  3KW2 A;  4H3Y A;  4YQC A;  4CND A;  4YVH A;  4YVI A;  1X7P A;  3L8U A;  4CNE A;  1NS5 A;  4XBO A;  3AXZ A;  4YPZ A;  1IPA A;  4YQP A;  5GMC A;  3ILK A;  2V3K A;  4YQA A;  3NK6 A;  3N4J A;  4YQJ A;  1UAK A;  1V6Z A;  4X3M A;  2CX8 A;  3DCM X;  4YPW A;  1VHY A;  4FAK A;  4YQQ A;  3BBH A;  3OIJ A;  1V2X A;  4YQT A;  3AI9 X;  4L69 A;  2O3A A;  1Z85 A;  4KGN A;  4YQ1 A;  2EGW A;  1TO0 A;  1VHK A;  4CNG A;  3OII A;  5GM8 A;  4YQG A;  4JAK A;  1NXZ A;  4YQN A;  1K3R A;  3OIN A;  4YQD A;  4MCB A;  1ZJR A;  4H3Z A;  1UAL A;  4X3L A;  4YQO A;  4YQ2 A;  2V3J A;  1OY5 A;  3QUV A;  4YQ6 A;  4E8B A;  1J85 A;  4YVJ A;  2NWA A;  3KTY A;  1VH0 A;  4J3C A;  5D9F A;  4YQS A;  2QWV A;  2Z0Y A;  4YQR A;  3AIA A;  4MCC A;  4CNF A;  4IG6 A;  3N4K A;  2HA8 A;  3KNU A;  1UAM A;  5CO4 A;  4YQ7 A;  4YVG A;  4RG1 A;  3GYQ A;  4YQ3 A; 
#chains in the Genus database with same CATH topology
 5HL7 S;  4PZK A;  4IOC S;  4IOA S;  4YQ9 A;  4P2B A;  4YQ5 A;  4YPX A;  1O0B A;  4MCD A;  3IC6 A;  4YQ4 A;  1D6K A;  1UAJ A;  4KDZ A;  4JWJ A;  4JXZ A;  5FAI A;  3E5Y A;  4JWF A;  4WFA S;  1P9P A;  4YQ8 A;  4JYZ A;  2QMM A;  2YY8 A;  1O6D A;  4YVK A;  2EGV A;  3IEF A;  5JVG S;  5GMB A;  4JAL A;  3NK7 A;  1X7O A;  3KY7 A;  1DFU P;  5GAH W;  2I6D A;  3BBE A;  4WFN S;  1GTS A;  1GZ0 A;  3O7B A;  5GAG W;  3BBD A;  4YQK A;  3ONP A;  4YQ0 A;  4YPY A;  4YQI A;  4YQL A;  4YQB A;  1MXI A;  3KW2 A;  4H3Y A;  2G6G A;  5JVH S;  4YQC A;  5GAE W;  4CND A;  4YVH A;  1QRS A;  5DM7 S;  5GAD W;  1X7P A;  3L8U A;  4CNE A;  4YVI A;  1NS5 A;  4V19 4;  2ZJR S;  4XBO A;  3AXZ A;  4YPZ A;  1IPA A;  4YQP A;  5GMC A;  3ILK A;  2V3K A;  3CZB A;  4YQA A;  1EXD A;  3NK6 A;  4WFB S;  3N4J A;  4YQJ A;  5BNZ A;  1UAK A;  1V6Z A;  4X3M A;  4UY8 8;  2CX8 A;  4WCE S;  3DCM X;  4YPW A;  1VHY A;  4FAK A;  4YQQ A;  2G5D A;  4H3S A;  3BBH A;  2RD2 A;  1QRU A;  1V2X A;  3OIJ A;  4YQT A;  2ZJQ S;  3AI9 X;  4L69 A;  2GAE A;  4JXX A;  3X1L B;  2O3A A;  4IO9 S;  1Z85 A;  4KGN A;  3AII A;  3W2W B;  4YQ1 A;  2EGW A;  1TO0 A;  1VHK A;  2PNW A;  4CNG A;  3OII A;  5GM8 A;  4YQG A;  3PIP S;  1QRT A;  4JAK A;  1NXZ A;  4YQN A;  1K3R A;  3OIN A;  1FEU A;  4YQD A;  4JWH A;  4MCB A;  2RE8 A;  5DM6 S;  2ZJP S;  2AE0 X;  4WF9 S;  1ZJR A;  4H3Z A;  1UAL A;  4FMW A;  4JWG A;  4X3L A;  4YQO A;  4YQ2 A;  2V3J A;  2PIC A;  1OY5 A;  1B75 A;  3QUV A;  1GTR A;  1UDX A;  4YQ6 A;  3PIO S;  4E8B A;  1J85 A;  2PJJ A;  4YVJ A;  1ZJW A;  2NWA A;  3KTY A;  3W2V B;  2HZ7 A;  1O0C A;  1VH0 A;  1NYL A;  4J3C A;  1EUQ A;  1QTQ A;  5D9F A;  4YQS A;  2QWV A;  2Z0Y A;  4YQR A;  3DLL S;  3AIA A;  4MCC A;  4CNF A;  1EUY A;  4IG6 A;  3N4K A;  2HA8 A;  3KNU A;  1UAM A;  5CO4 A;  4YQ7 A;  4YVG A;  2PI8 A;  5IZN A;  3J7Z V;  3CF5 S;  4RG1 A;  4H4K A;  4U67 S;  3GYQ A;  4YQ3 A; 
#chains in the Genus database with same CATH homology
 4PZK A;  4YQ9 A;  4YQ5 A;  4YPX A;  4MCD A;  3IC6 A;  4YQ4 A;  1UAJ A;  4KDZ A;  4JWJ A;  5FAI A;  3E5Y A;  4JWF A;  1P9P A;  4YQ8 A;  2QMM A;  2YY8 A;  1O6D A;  4YVK A;  2EGV A;  3IEF A;  5GMB A;  4JAL A;  3NK7 A;  1X7O A;  3KY7 A;  2I6D A;  3BBE A;  1GZ0 A;  3O7B A;  3BBD A;  4YQK A;  3ONP A;  4YQ0 A;  4YPY A;  4YQI A;  4YQL A;  4YQB A;  1MXI A;  3KW2 A;  4H3Y A;  4YQC A;  4CND A;  4YVH A;  4YVI A;  1X7P A;  3L8U A;  4CNE A;  1NS5 A;  4XBO A;  3AXZ A;  4YPZ A;  1IPA A;  4YQP A;  5GMC A;  3ILK A;  2V3K A;  4YQA A;  3NK6 A;  3N4J A;  4YQJ A;  1UAK A;  1V6Z A;  4X3M A;  2CX8 A;  3DCM X;  4YPW A;  1VHY A;  4FAK A;  4YQQ A;  3BBH A;  3OIJ A;  1V2X A;  4YQT A;  3AI9 X;  4L69 A;  2O3A A;  1Z85 A;  4KGN A;  4YQ1 A;  2EGW A;  1TO0 A;  1VHK A;  4CNG A;  3OII A;  5GM8 A;  4YQG A;  4JAK A;  1NXZ A;  4YQN A;  1K3R A;  3OIN A;  4YQD A;  4JWH A;  4MCB A;  1ZJR A;  4H3Z A;  1UAL A;  4FMW A;  4JWG A;  4X3L A;  4YQO A;  4YQ2 A;  2V3J A;  1OY5 A;  3QUV A;  4YQ6 A;  4E8B A;  1J85 A;  4YVJ A;  2NWA A;  3KTY A;  1VH0 A;  4J3C A;  5D9F A;  4YQS A;  2QWV A;  2Z0Y A;  4YQR A;  3AIA A;  4MCC A;  4CNF A;  4IG6 A;  3N4K A;  2HA8 A;  3KNU A;  1UAM A;  5CO4 A;  4YQ7 A;  4YVG A;  4RG1 A;  3GYQ A;  4YQ3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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