2EGVA

Crystal structure of rrna methyltransferase with sam ligand
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
229
structure length
229
Chain Sequence
MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of rRNA methyltransferase with SAM ligand
rcsb
molecule tags Rna methyltransferase
source organism Aquifex aeolicus
molecule keywords UPF0088 protein aq_165
total genus 72
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egvA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egvA02
4YQJA 3O7BA 4J3CA 3IEFA 4YQCA 5GM8A 4YVKA 3QUVA 4YPXA 3KY7A 1VHKA 2QMMA 1O6DA 4CNFA 4L69A 1OY5A 3BBEA 3NK6A 4CNGA 4YQ5A 4H3YA 1J85A 3IC6A 3OIIA 4YQSA 3AXZA 2HA8A 1V2XA 4X3LA 4YQLA 4YQ9A 4JAKA 4YQPA 1NS5A 3AI9X 2EGVA 4X3MA 4H3ZA 1NXZA 3ONPA 4YVHA 1UAMA 1IPAA 1TO0A 4YPYA 2I6DA 3KNUA 5D9FA 4YPWA 4YQ2A 4YQAA 2QWVA 4YVGA 4YQBA 3ILKA 4RG1A 4YQ6A 5GMBA 4YVIA 4YQ0A 4YQDA 3OIJA 2NWAA 5FAIA 4FAKA 4YVJA 4YQ1A 1MXIA 3DCMX 4YQ8A 1GZ0A 3N4JA 4PZKA 4JALA 1Z85A 4YQ7A 5CO4A 2YY8A 4CNEA 1V6ZA 3N4KA 2Z0YA 4E8BA 4CNDA 2CX8A 3BBHA 4YQKA 4YQ3A 4MCDA 1UALA 2V3KA 2EGWA 3NK7A 1X7PA 4YQGA 3AIAA 4YQNA 2V3JA 3L8UA 1X7OA 4MCBA 4YQRA 4YPZA 3KW2A 1ZJRA 1UAKA 4KDZA 1UAJA 3BBDA 4YQOA 1VH0A 1P9PA 4YQ4A 4YQIA 1K3RA 5GMCA 3KTYA 4IG6A 3E5YA 4XBOA 4KGNA 4YQQA 4YQTA 4MCCA 1VHYA 3OINA 2O3AA 3GYQA
chains in the Genus database with same CATH superfamily
4YQJA 3O7BA 4J3CA 1QTQA 3IEFA 4U67S 1NYLA 5HL7S 3QUVA 4YQCA 5GM8A 4YPXA 3KY7A 1VHKA 4WCES 4JXZA 3J7ZV 1O6DA 2QMMA 4CNFA 4L69A 1OY5A 3BBEA 3NK6A 1GTSA 5GAGW 4V194 4CNGA 4YQ5A 2PI8A 1B75A 1J85A 4H3YA 3IC6A 3OIIA 5DM6S 4YQSA 1EUYA 3AXZA 2HA8A 3GYQA 3PIOS 2ZJQS 1V2XA 4X3LA 4YQLA 4YQ9A 4JAKA 4YQPA 1NS5A 3AI9X 2EGVA 4WF9S 4X3MA 4H3SA 4H3ZA 1NXZA 4H4KA 3ONPA 4YVKA 4YVHA 1FEUA 2G5DA 1UAMA 1IPAA 1TO0A 2RE8A 4YPYA 2I6DA 3KNUA 5D9FA 4YPWA 4YQ2A 4YQAA 2GAEA 2QWVA 4WFNS 4YVGA 1ZJWA 4YQBA 3ILKA 4IOCS 4RG1A 1O0BA 4WFAS 4IOAS 1D6KA 2G6GA 4YQ6A 1DFUP 5GMBA 4YVIA 4YQ0A 4YQDA 3OIJA 2NWAA 5JVHS 5FAIA 4FAKA 4YVJA 2PICA 2PNWA 4YQ1A 4JWJA 1EXDA 1MXIA 4JYZA 4FMWA 3DCMX 4YQ8A 4P2BA 1QRUA 1GZ0A 3N4JA 4JXXA 4PZKA 3X1LB 1GTRA 4JALA 4JWHA 1Z85A 4YQ7A 5CO4A 2ZJRS 2YY8A 4CNEA 1V6ZA 3N4KA 2Z0YA 4E8BA 2AE0X 5GAHW 3PIPS 4CNDA 2CX8A 3W2WB 3BBHA 4YQKA 4YQ3A 3W2VB 4MCDA 1UALA 2V3KA 2EGWA 3NK7A 1X7PA 4YQGA 3AIAA 4YQNA 2PJJA 2V3JA 1O0CA 2RD2A 3L8UA 1X7OA 4MCBA 4YQRA 4YPZA 3KW2A 1ZJRA 5GADW 1QRTA 1QRSA 1UAKA 4JWGA 4KDZA 1UAJA 3BBDA 4YQOA 4JWFA 2ZJPS 1VH0A 5BNZA 5IZNA 1P9PA 4YQ4A 4IO9S 4YQIA 1K3RA 4WFBS 3DLLS 5GMCA 2HZ7A 3KTYA 4IG6A 3E5YA 4XBOA 5GAEW 4KGNA 1UDXA 4YQQA 4YQTA 4MCCA 3AIIA 3CZBA 1VHYA 4UY88 3OINA 3CF5S 2O3AA 1EUQA 5DM7S 5JVGS
chains in the Genus database with same CATH topology
4YQJA 3O7BA 4J3CA 3IEFA 4YQCA 5GM8A 4YVKA 3QUVA 4YPXA 3KY7A 1VHKA 2QMMA 1O6DA 4CNFA 4L69A 1OY5A 3BBEA 3NK6A 4CNGA 4YQ5A 4H3YA 1J85A 3IC6A 3OIIA 4YQSA 3AXZA 2HA8A 1V2XA 4X3LA 4YQLA 4YQ9A 4JAKA 4YQPA 1NS5A 3AI9X 2EGVA 4X3MA 4H3ZA 1NXZA 3ONPA 4YVHA 1UAMA 1IPAA 1TO0A 4YPYA 2I6DA 3KNUA 5D9FA 4YPWA 4YQ2A 4YQAA 2QWVA 4YVGA 4YQBA 3ILKA 4RG1A 4YQ6A 5GMBA 4YVIA 4YQ0A 4YQDA 3OIJA 2NWAA 5FAIA 4FAKA 4YVJA 4YQ1A 4JWJA 1MXIA 4FMWA 3DCMX 4YQ8A 1GZ0A 3N4JA 4PZKA 4JALA 4JWHA 1Z85A 4YQ7A 5CO4A 2YY8A 4CNEA 1V6ZA 3N4KA 2Z0YA 4E8BA 4CNDA 2CX8A 3BBHA 4YQKA 4YQ3A 4MCDA 1UALA 2V3KA 2EGWA 3NK7A 1X7PA 4YQGA 3AIAA 4YQNA 2V3JA 3L8UA 1X7OA 4MCBA 4YQRA 4YPZA 3KW2A 1ZJRA 1UAKA 4JWGA 4KDZA 1UAJA 3BBDA 4YQOA 4JWFA 1VH0A 1P9PA 4YQ4A 4YQIA 1K3RA 5GMCA 3KTYA 4IG6A 3E5YA 4XBOA 4KGNA 4YQQA 4YQTA 4MCCA 1VHYA 3OINA 2O3AA 3GYQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQJ A;  3O7B A;  4J3C A;  3IEF A;  4YQC A;  5GM8 A;  4YVK A;  3QUV A;  4YPX A;  3KY7 A;  1VHK A;  2QMM A;  1O6D A;  4CNF A;  4L69 A;  1OY5 A;  3BBE A;  3NK6 A;  4CNG A;  4YQ5 A;  4H3Y A;  1J85 A;  3IC6 A;  3OII A;  4YQS A;  3AXZ A;  2HA8 A;  1V2X A;  4X3L A;  4YQL A;  4YQ9 A;  4JAK A;  4YQP A;  1NS5 A;  3AI9 X;  2EGV A;  4X3M A;  4H3Z A;  1NXZ A;  3ONP A;  4YVH A;  1UAM A;  1IPA A;  1TO0 A;  4YPY A;  2I6D A;  3KNU A;  5D9F A;  4YPW A;  4YQ2 A;  4YQA A;  2QWV A;  4YVG A;  4YQB A;  3ILK A;  4RG1 A;  4YQ6 A;  5GMB A;  4YVI A;  4YQ0 A;  4YQD A;  3OIJ A;  2NWA A;  5FAI A;  4FAK A;  4YVJ A;  4YQ1 A;  1MXI A;  3DCM X;  4YQ8 A;  1GZ0 A;  3N4J A;  4PZK A;  4JAL A;  1Z85 A;  4YQ7 A;  5CO4 A;  2YY8 A;  4CNE A;  1V6Z A;  3N4K A;  2Z0Y A;  4E8B A;  4CND A;  2CX8 A;  3BBH A;  4YQK A;  4YQ3 A;  4MCD A;  1UAL A;  2V3K A;  2EGW A;  3NK7 A;  1X7P A;  4YQG A;  3AIA A;  4YQN A;  2V3J A;  3L8U A;  1X7O A;  4MCB A;  4YQR A;  4YPZ A;  3KW2 A;  1ZJR A;  1UAK A;  4KDZ A;  1UAJ A;  3BBD A;  4YQO A;  1VH0 A;  1P9P A;  4YQ4 A;  4YQI A;  1K3R A;  5GMC A;  3KTY A;  4IG6 A;  3E5Y A;  4XBO A;  4KGN A;  4YQQ A;  4YQT A;  4MCC A;  1VHY A;  3OIN A;  2O3A A;  3GYQ A; 
#chains in the Genus database with same CATH topology
 4YQJ A;  3O7B A;  4J3C A;  1QTQ A;  3IEF A;  4U67 S;  1NYL A;  5HL7 S;  3QUV A;  4YQC A;  5GM8 A;  4YPX A;  3KY7 A;  1VHK A;  4WCE S;  4JXZ A;  3J7Z V;  1O6D A;  2QMM A;  4CNF A;  4L69 A;  1OY5 A;  3BBE A;  3NK6 A;  1GTS A;  5GAG W;  4V19 4;  4CNG A;  4YQ5 A;  2PI8 A;  1B75 A;  1J85 A;  4H3Y A;  3IC6 A;  3OII A;  5DM6 S;  4YQS A;  1EUY A;  3AXZ A;  2HA8 A;  3GYQ A;  3PIO S;  2ZJQ S;  1V2X A;  4X3L A;  4YQL A;  4YQ9 A;  4JAK A;  4YQP A;  1NS5 A;  3AI9 X;  2EGV A;  4WF9 S;  4X3M A;  4H3S A;  4H3Z A;  1NXZ A;  4H4K A;  3ONP A;  4YVK A;  4YVH A;  1FEU A;  2G5D A;  1UAM A;  1IPA A;  1TO0 A;  2RE8 A;  4YPY A;  2I6D A;  3KNU A;  5D9F A;  4YPW A;  4YQ2 A;  4YQA A;  2GAE A;  2QWV A;  4WFN S;  4YVG A;  1ZJW A;  4YQB A;  3ILK A;  4IOC S;  4RG1 A;  1O0B A;  4WFA S;  4IOA S;  1D6K A;  2G6G A;  4YQ6 A;  1DFU P;  5GMB A;  4YVI A;  4YQ0 A;  4YQD A;  3OIJ A;  2NWA A;  5JVH S;  5FAI A;  4FAK A;  4YVJ A;  2PIC A;  2PNW A;  4YQ1 A;  4JWJ A;  1EXD A;  1MXI A;  4JYZ A;  4FMW A;  3DCM X;  4YQ8 A;  4P2B A;  1QRU A;  1GZ0 A;  3N4J A;  4JXX A;  4PZK A;  3X1L B;  1GTR A;  4JAL A;  4JWH A;  1Z85 A;  4YQ7 A;  5CO4 A;  2ZJR S;  2YY8 A;  4CNE A;  1V6Z A;  3N4K A;  2Z0Y A;  4E8B A;  2AE0 X;  5GAH W;  3PIP S;  4CND A;  2CX8 A;  3W2W B;  3BBH A;  4YQK A;  4YQ3 A;  3W2V B;  4MCD A;  1UAL A;  2V3K A;  2EGW A;  3NK7 A;  1X7P A;  4YQG A;  3AIA A;  4YQN A;  2PJJ A;  2V3J A;  1O0C A;  2RD2 A;  3L8U A;  1X7O A;  4MCB A;  4YQR A;  4YPZ A;  3KW2 A;  1ZJR A;  5GAD W;  1QRT A;  1QRS A;  1UAK A;  4JWG A;  4KDZ A;  1UAJ A;  3BBD A;  4YQO A;  4JWF A;  2ZJP S;  1VH0 A;  5BNZ A;  5IZN A;  1P9P A;  4YQ4 A;  4IO9 S;  4YQI A;  1K3R A;  4WFB S;  3DLL S;  5GMC A;  2HZ7 A;  3KTY A;  4IG6 A;  3E5Y A;  4XBO A;  5GAE W;  4KGN A;  1UDX A;  4YQQ A;  4YQT A;  4MCC A;  3AII A;  3CZB A;  1VHY A;  4UY8 8;  3OIN A;  3CF5 S;  2O3A A;  1EUQ A;  5DM7 S;  5JVG S; 
#chains in the Genus database with same CATH homology
 4YQJ A;  3O7B A;  4J3C A;  3IEF A;  4YQC A;  5GM8 A;  4YVK A;  3QUV A;  4YPX A;  3KY7 A;  1VHK A;  2QMM A;  1O6D A;  4CNF A;  4L69 A;  1OY5 A;  3BBE A;  3NK6 A;  4CNG A;  4YQ5 A;  4H3Y A;  1J85 A;  3IC6 A;  3OII A;  4YQS A;  3AXZ A;  2HA8 A;  1V2X A;  4X3L A;  4YQL A;  4YQ9 A;  4JAK A;  4YQP A;  1NS5 A;  3AI9 X;  2EGV A;  4X3M A;  4H3Z A;  1NXZ A;  3ONP A;  4YVH A;  1UAM A;  1IPA A;  1TO0 A;  4YPY A;  2I6D A;  3KNU A;  5D9F A;  4YPW A;  4YQ2 A;  4YQA A;  2QWV A;  4YVG A;  4YQB A;  3ILK A;  4RG1 A;  4YQ6 A;  5GMB A;  4YVI A;  4YQ0 A;  4YQD A;  3OIJ A;  2NWA A;  5FAI A;  4FAK A;  4YVJ A;  4YQ1 A;  4JWJ A;  1MXI A;  4FMW A;  3DCM X;  4YQ8 A;  1GZ0 A;  3N4J A;  4PZK A;  4JAL A;  4JWH A;  1Z85 A;  4YQ7 A;  5CO4 A;  2YY8 A;  4CNE A;  1V6Z A;  3N4K A;  2Z0Y A;  4E8B A;  4CND A;  2CX8 A;  3BBH A;  4YQK A;  4YQ3 A;  4MCD A;  1UAL A;  2V3K A;  2EGW A;  3NK7 A;  1X7P A;  4YQG A;  3AIA A;  4YQN A;  2V3J A;  3L8U A;  1X7O A;  4MCB A;  4YQR A;  4YPZ A;  3KW2 A;  1ZJR A;  1UAK A;  4JWG A;  4KDZ A;  1UAJ A;  3BBD A;  4YQO A;  4JWF A;  1VH0 A;  1P9P A;  4YQ4 A;  4YQI A;  1K3R A;  5GMC A;  3KTY A;  4IG6 A;  3E5Y A;  4XBO A;  4KGN A;  4YQQ A;  4YQT A;  4MCC A;  1VHY A;  3OIN A;  2O3A A;  3GYQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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