2EH4A

Mutant t146m structure of ph0725 from pyrococcus horikoshii ot3
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPMSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutant T146M structure of PH0725 from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2007-03-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2eh4A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2eh4A01
2EL3A 2ZVBA 1WYZA 2E4NA 2EK3A 2OWVA 2BB3A 2E0KA 3FFYA 2ED3A 2E15A 2E8HA 2ZVCA 1VCEA 3ND1A 2P6DA 5HW4A 1VE2A 2E8RA 2E16A 2DSIA 2HUXA 2DV5A 2PCGA 2OWGA 2OWFA 2EH4A 4E16A 2P6IA 2HUQA 1V9AA 2ELDA 2DXXA 2PB4A 3NUTA 3I4TA 3FQ6A 3NEIA 2DSGA 2P6LA 2EL0A 2EHCA 2PCHA 2E7RA 2P9DA 2EH2A 2PCKA 2P5CA 2DV7A 2EGBA 2EHLA 2EJZA 2PCAA 2EMUA 2EK7A 2PB5A 2E07A 2DEKA 2EL2A 2EMRA 2EL1A 2QBUA 2E8SA 2P2XA 2OWUA 1WDEA 2DV3A 2EJKA 2YBOA 1S4DA 2HR8A 2E0NA 2YBQA 2DV4A 2PCMA 2E4RA 2CBFA 2NPNA 2PB6A 3HH1A 1CBFA 2EK4A 2Z6RA 2P5FA 2EH5A 2EJJA 2DSHA 2P6KA 1VHVA 2DXVA 2ELEA 1VA0A 2EGSA 2ED5A 2E17A 2EN5A 2E8QA 2ENIA 3NDCA 2PCIA 2HUTA 2DXWA 2EK2A 1PJTA 1WNGA 1PJQA 2HUVA 2EKAA 1PJSA 3KWPA 2OWKA 2EGLA 2E08A 2EEQA
chains in the Genus database with same CATH superfamily
2EL3A 2ZVBA 1WYZA 4MUXA 3KE8A 2E4NA 2EK3A 2OWVA 3TIXB 2BB3A 2E0KA 3FFYA 2ED3A 3ZGLA 2E15A 4H4CA 2E8HA 2ZVCA 3UV3A 1VCEA 3ND1A 3T0FA 2P6DA 5HW4A 1VE2A 2E8RA 2E16A 2DSIA 3UV6A 2HUXA 2DV5A 4H4DA 2PCGA 4H4EA 2OWGA 2OWFA 2EH4A 4E16A 2P6IA 2HUQA 3URKA 1V9AA 2ELDA 2DXXA 2PB4A 3NUTA 3I4TA 3FQ6A 3UV7A 4MV5A 3NEIA 2DSGA 3ZGNA 2P6LA 2EL0A 2EHCA 2PCHA 2E7RA 2P9DA 2EH2A 3KEMA 2PCKA 2P5CA 2DV7A 3KEFA 2EGBA 2EHLA 2EJZA 2PCAA 3KE9A 2EMUA 2EK7A 2PB5A 2E07A 2DEKA 2EL2A 2EMRA 2EL1A 2QBUA 2E8SA 2P2XA 2OWUA 1WDEA 2DV3A 2EJKA 2YBOA 4EB3A 1S4DA 2HR8A 3LMMA 2KYYA 2E0NA 2YBQA 2DV4A 2PCMA 3UWMA 2E4RA 2CBFA 2NPNA 2PB6A 3HH1A 1CBFA 2EK4A 2Z6RA 3F7TA 2P5FA 2EH5A 2EJJA 2DSHA 2P6KA 1VHVA 2DXVA 2ELEA 3T0GA 1VA0A 2EGSA 3DNFA 2ED5A 4MUYA 4MV0A 2E17A 2EN5A 3SZLA 2E8QA 2ENIA 3NDCA 2PCIA 2HUTA 2DXWA 2EK2A 4N7BA 1PJTA 1WNGA 1PJQA 2HUVA 2EKAA 1PJSA 3KWPA 3UTCA 3SZUA 3KELA 3SZOA 2OWKA 2EGLA 2E08A 2EEQA 3UTDA
chains in the Genus database with same CATH topology
2EL3A 2ZVBA 1WYZA 4MUXA 3KE8A 2E4NA 2EK3A 2OWVA 3TIXB 2BB3A 2E0KA 3FFYA 2ED3A 3ZGLA 2E15A 4H4CA 2E8HA 2ZVCA 3UV3A 1VCEA 3ND1A 3T0FA 2P6DA 5HW4A 1VE2A 2E8RA 2E16A 2DSIA 3UV6A 2HUXA 2DV5A 4H4DA 2PCGA 4H4EA 2OWGA 2OWFA 2EH4A 4E16A 2P6IA 2HUQA 3URKA 1V9AA 2ELDA 2DXXA 2PB4A 3NUTA 3I4TA 3FQ6A 3UV7A 4MV5A 3NEIA 2DSGA 3ZGNA 2P6LA 2EL0A 2EHCA 2PCHA 2E7RA 2P9DA 2EH2A 3KEMA 2PCKA 2P5CA 2DV7A 3KEFA 2EGBA 2EHLA 2EJZA 2PCAA 3KE9A 2EMUA 2EK7A 2PB5A 2E07A 2DEKA 2EL2A 2EMRA 2EL1A 2QBUA 2E8SA 2P2XA 2OWUA 1WDEA 2DV3A 2EJKA 2YBOA 4EB3A 1S4DA 2HR8A 3LMMA 2KYYA 2E0NA 2YBQA 2DV4A 2PCMA 3UWMA 2E4RA 2CBFA 2NPNA 2PB6A 3HH1A 1CBFA 2EK4A 2Z6RA 3F7TA 2P5FA 2EH5A 2EJJA 2DSHA 2P6KA 1VHVA 2DXVA 2ELEA 3T0GA 1VA0A 2EGSA 3DNFA 2ED5A 4MUYA 4MV0A 2E17A 2EN5A 3SZLA 2E8QA 2ENIA 3NDCA 2PCIA 2HUTA 2DXWA 2EK2A 4N7BA 1PJTA 1WNGA 1PJQA 2HUVA 2EKAA 1PJSA 3KWPA 3UTCA 3SZUA 3KELA 3SZOA 2OWKA 2EGLA 2E08A 2EEQA 3UTDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EL3 A;  2ZVB A;  1WYZ A;  2E4N A;  2EK3 A;  2OWV A;  2BB3 A;  2E0K A;  3FFY A;  2ED3 A;  2E15 A;  2E8H A;  2ZVC A;  1VCE A;  3ND1 A;  2P6D A;  5HW4 A;  1VE2 A;  2E8R A;  2E16 A;  2DSI A;  2HUX A;  2DV5 A;  2PCG A;  2OWG A;  2OWF A;  2EH4 A;  4E16 A;  2P6I A;  2HUQ A;  1V9A A;  2ELD A;  2DXX A;  2PB4 A;  3NUT A;  3I4T A;  3FQ6 A;  3NEI A;  2DSG A;  2P6L A;  2EL0 A;  2EHC A;  2PCH A;  2E7R A;  2P9D A;  2EH2 A;  2PCK A;  2P5C A;  2DV7 A;  2EGB A;  2EHL A;  2EJZ A;  2PCA A;  2EMU A;  2EK7 A;  2PB5 A;  2E07 A;  2DEK A;  2EL2 A;  2EMR A;  2EL1 A;  2QBU A;  2E8S A;  2P2X A;  2OWU A;  1WDE A;  2DV3 A;  2EJK A;  2YBO A;  1S4D A;  2HR8 A;  2E0N A;  2YBQ A;  2DV4 A;  2PCM A;  2E4R A;  2CBF A;  2NPN A;  2PB6 A;  3HH1 A;  1CBF A;  2EK4 A;  2Z6R A;  2P5F A;  2EH5 A;  2EJJ A;  2DSH A;  2P6K A;  1VHV A;  2DXV A;  2ELE A;  1VA0 A;  2EGS A;  2ED5 A;  2E17 A;  2EN5 A;  2E8Q A;  2ENI A;  3NDC A;  2PCI A;  2HUT A;  2DXW A;  2EK2 A;  1PJT A;  1WNG A;  1PJQ A;  2HUV A;  2EKA A;  1PJS A;  3KWP A;  2OWK A;  2EGL A;  2E08 A;  2EEQ A; 
#chains in the Genus database with same CATH topology
 2EL3 A;  2ZVB A;  1WYZ A;  4MUX A;  3KE8 A;  2E4N A;  2EK3 A;  2OWV A;  3TIX B;  2BB3 A;  2E0K A;  3FFY A;  2ED3 A;  3ZGL A;  2E15 A;  4H4C A;  2E8H A;  2ZVC A;  3UV3 A;  1VCE A;  3ND1 A;  3T0F A;  2P6D A;  5HW4 A;  1VE2 A;  2E8R A;  2E16 A;  2DSI A;  3UV6 A;  2HUX A;  2DV5 A;  4H4D A;  2PCG A;  4H4E A;  2OWG A;  2OWF A;  2EH4 A;  4E16 A;  2P6I A;  2HUQ A;  3URK A;  1V9A A;  2ELD A;  2DXX A;  2PB4 A;  3NUT A;  3I4T A;  3FQ6 A;  3UV7 A;  4MV5 A;  3NEI A;  2DSG A;  3ZGN A;  2P6L A;  2EL0 A;  2EHC A;  2PCH A;  2E7R A;  2P9D A;  2EH2 A;  3KEM A;  2PCK A;  2P5C A;  2DV7 A;  3KEF A;  2EGB A;  2EHL A;  2EJZ A;  2PCA A;  3KE9 A;  2EMU A;  2EK7 A;  2PB5 A;  2E07 A;  2DEK A;  2EL2 A;  2EMR A;  2EL1 A;  2QBU A;  2E8S A;  2P2X A;  2OWU A;  1WDE A;  2DV3 A;  2EJK A;  2YBO A;  4EB3 A;  1S4D A;  2HR8 A;  3LMM A;  2KYY A;  2E0N A;  2YBQ A;  2DV4 A;  2PCM A;  3UWM A;  2E4R A;  2CBF A;  2NPN A;  2PB6 A;  3HH1 A;  1CBF A;  2EK4 A;  2Z6R A;  3F7T A;  2P5F A;  2EH5 A;  2EJJ A;  2DSH A;  2P6K A;  1VHV A;  2DXV A;  2ELE A;  3T0G A;  1VA0 A;  2EGS A;  3DNF A;  2ED5 A;  4MUY A;  4MV0 A;  2E17 A;  2EN5 A;  3SZL A;  2E8Q A;  2ENI A;  3NDC A;  2PCI A;  2HUT A;  2DXW A;  2EK2 A;  4N7B A;  1PJT A;  1WNG A;  1PJQ A;  2HUV A;  2EKA A;  1PJS A;  3KWP A;  3UTC A;  3SZU A;  3KEL A;  3SZO A;  2OWK A;  2EGL A;  2E08 A;  2EEQ A;  3UTD A; 
#chains in the Genus database with same CATH homology
 2EL3 A;  2ZVB A;  1WYZ A;  4MUX A;  3KE8 A;  2E4N A;  2EK3 A;  2OWV A;  3TIX B;  2BB3 A;  2E0K A;  3FFY A;  2ED3 A;  3ZGL A;  2E15 A;  4H4C A;  2E8H A;  2ZVC A;  3UV3 A;  1VCE A;  3ND1 A;  3T0F A;  2P6D A;  5HW4 A;  1VE2 A;  2E8R A;  2E16 A;  2DSI A;  3UV6 A;  2HUX A;  2DV5 A;  4H4D A;  2PCG A;  4H4E A;  2OWG A;  2OWF A;  2EH4 A;  4E16 A;  2P6I A;  2HUQ A;  3URK A;  1V9A A;  2ELD A;  2DXX A;  2PB4 A;  3NUT A;  3I4T A;  3FQ6 A;  3UV7 A;  4MV5 A;  3NEI A;  2DSG A;  3ZGN A;  2P6L A;  2EL0 A;  2EHC A;  2PCH A;  2E7R A;  2P9D A;  2EH2 A;  3KEM A;  2PCK A;  2P5C A;  2DV7 A;  3KEF A;  2EGB A;  2EHL A;  2EJZ A;  2PCA A;  3KE9 A;  2EMU A;  2EK7 A;  2PB5 A;  2E07 A;  2DEK A;  2EL2 A;  2EMR A;  2EL1 A;  2QBU A;  2E8S A;  2P2X A;  2OWU A;  1WDE A;  2DV3 A;  2EJK A;  2YBO A;  4EB3 A;  1S4D A;  2HR8 A;  3LMM A;  2KYY A;  2E0N A;  2YBQ A;  2DV4 A;  2PCM A;  3UWM A;  2E4R A;  2CBF A;  2NPN A;  2PB6 A;  3HH1 A;  1CBF A;  2EK4 A;  2Z6R A;  3F7T A;  2P5F A;  2EH5 A;  2EJJ A;  2DSH A;  2P6K A;  1VHV A;  2DXV A;  2ELE A;  3T0G A;  1VA0 A;  2EGS A;  3DNF A;  2ED5 A;  4MUY A;  4MV0 A;  2E17 A;  2EN5 A;  3SZL A;  2E8Q A;  2ENI A;  3NDC A;  2PCI A;  2HUT A;  2DXW A;  2EK2 A;  4N7B A;  1PJT A;  1WNG A;  1PJQ A;  2HUV A;  2EKA A;  1PJS A;  3KWP A;  3UTC A;  3SZU A;  3KEL A;  3SZO A;  2OWK A;  2EGL A;  2E08 A;  2EEQ A;  3UTD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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