2EH4A

Mutant t146m structure of ph0725 from pyrococcus horikoshii ot3
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPMSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutant T146M structure of PH0725 from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2007-03-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2eh4A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2eh4A01
3I4TA 2EH4A 2E17A 2P9DA 2E4RA 1WNGA 2CBFA 2EMRA 2PB5A 2ED5A 2P6KA 2DXXA 2EHCA 2PCGA 2PCIA 2P2XA 2E7RA 2HUTA 2E15A 3NEIA 2ZVBA 2EK3A 2EL1A 2Z6RA 1VE2A 1WYZA 2E8RA 3ND1A 2HUQA 2P5CA 2ENIA 2E8HA 2EMUA 2ELDA 2DV7A 2EGSA 2PCHA 2PCAA 1WDEA 2P6IA 2EL0A 1VA0A 2E0KA 2P6LA 2EL2A 4E16A 2P5FA 1PJQA 2DV5A 2EGLA 2E08A 2YBOA 2EJZA 2EKAA 2OWFA 2HUXA 2HR8A 2E8QA 2E16A 2EGBA 2EK7A 2BB3A 1PJSA 2ED3A 2PB6A 1V9AA 5HW4A 2EH5A 3NDCA 2PCMA 2OWVA 2DV3A 3NUTA 2EEQA 2OWKA 2ZVCA 1S4DA 3FQ6A 2OWUA 2EH2A 2EL3A 1VHVA 2OWGA 2DV4A 2DSGA 1VCEA 2E8SA 2E0NA 2EK4A 2DXWA 2NPNA 2PCKA 2EK2A 2YBQA 3KWPA 2E07A 2DXVA 3HH1A 2EN5A 2DEKA 3FFYA 2EJKA 2HUVA 2PB4A 2QBUA 2DSHA 2ELEA 1CBFA 2DSIA 2E4NA 2EHLA 2P6DA 2EJJA 1PJTA
chains in the Genus database with same CATH superfamily
3I4TA 2EH4A 2E17A 3UV3A 4N7BA 2P9DA 3T0FA 2E4RA 1WNGA 3UV7A 2CBFA 3T0GA 2EMRA 2PB5A 2ED5A 2P6KA 3TIXB 3UWMA 2DXXA 2EHCA 2PCGA 2PCIA 2P2XA 2E7RA 2HUTA 2E15A 3NEIA 2ZVBA 4MUYA 2EK3A 2EL1A 2Z6RA 1VE2A 1WYZA 2E8RA 3ND1A 2HUQA 3SZLA 2P5CA 3ZGLA 4H4DA 2ENIA 2E8HA 2EMUA 2ELDA 3UTDA 2DV7A 2EGSA 2PCHA 2PCAA 1WDEA 2P6IA 2EL0A 1VA0A 2E0KA 4H4CA 3KE8A 3KEMA 2P6LA 4MV5A 2EL2A 4E16A 3F7TA 4MUXA 2P5FA 1PJQA 3KELA 2DV5A 2EGLA 2E08A 2YBOA 3URKA 3KEFA 2EJZA 2EKAA 2OWFA 2HUXA 3SZUA 2HR8A 2E8QA 2E16A 2EGBA 2EK7A 2BB3A 1PJSA 2ED3A 2PB6A 1V9AA 4H4EA 5HW4A 2EH5A 3NDCA 2PCMA 2OWVA 2DV3A 3NUTA 2EEQA 2OWKA 2ZVCA 1S4DA 3FQ6A 2OWUA 2EH2A 2EL3A 1VHVA 2OWGA 2DV4A 2DSGA 1VCEA 2E8SA 3LMMA 2E0NA 2EK4A 4MV0A 2DXWA 2NPNA 3DNFA 4EB3A 3SZOA 2PCKA 2EK2A 2YBQA 3KWPA 2E07A 2DXVA 2KYYA 3HH1A 3UV6A 2EN5A 3ZGNA 2DEKA 3FFYA 2EJKA 3UTCA 2HUVA 2PB4A 2QBUA 2DSHA 2ELEA 3KE9A 1CBFA 2DSIA 2E4NA 2EHLA 2P6DA 2EJJA 1PJTA
chains in the Genus database with same CATH topology
3I4TA 2EH4A 2E17A 3UV3A 4N7BA 2P9DA 3T0FA 2E4RA 1WNGA 3UV7A 2CBFA 3T0GA 2EMRA 2PB5A 2ED5A 2P6KA 3TIXB 3UWMA 2DXXA 2EHCA 2PCGA 2PCIA 2P2XA 2E7RA 2HUTA 2E15A 3NEIA 2ZVBA 4MUYA 2EK3A 2EL1A 2Z6RA 1VE2A 1WYZA 2E8RA 3ND1A 2HUQA 3SZLA 2P5CA 3ZGLA 4H4DA 2ENIA 2E8HA 2EMUA 2ELDA 3UTDA 2DV7A 2EGSA 2PCHA 2PCAA 1WDEA 2P6IA 2EL0A 1VA0A 2E0KA 4H4CA 3KE8A 3KEMA 2P6LA 4MV5A 2EL2A 4E16A 3F7TA 4MUXA 2P5FA 1PJQA 3KELA 2DV5A 2EGLA 2E08A 2YBOA 3URKA 3KEFA 2EJZA 2EKAA 2OWFA 2HUXA 3SZUA 2HR8A 2E8QA 2E16A 2EGBA 2EK7A 2BB3A 1PJSA 2ED3A 2PB6A 1V9AA 4H4EA 5HW4A 2EH5A 3NDCA 2PCMA 2OWVA 2DV3A 3NUTA 2EEQA 2OWKA 2ZVCA 1S4DA 3FQ6A 2OWUA 2EH2A 2EL3A 1VHVA 2OWGA 2DV4A 2DSGA 1VCEA 2E8SA 3LMMA 2E0NA 2EK4A 4MV0A 2DXWA 2NPNA 3DNFA 4EB3A 3SZOA 2PCKA 2EK2A 2YBQA 3KWPA 2E07A 2DXVA 2KYYA 3HH1A 3UV6A 2EN5A 3ZGNA 2DEKA 3FFYA 2EJKA 3UTCA 2HUVA 2PB4A 2QBUA 2DSHA 2ELEA 3KE9A 1CBFA 2DSIA 2E4NA 2EHLA 2P6DA 2EJJA 1PJTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I4T A;  2EH4 A;  2E17 A;  2P9D A;  2E4R A;  1WNG A;  2CBF A;  2EMR A;  2PB5 A;  2ED5 A;  2P6K A;  2DXX A;  2EHC A;  2PCG A;  2PCI A;  2P2X A;  2E7R A;  2HUT A;  2E15 A;  3NEI A;  2ZVB A;  2EK3 A;  2EL1 A;  2Z6R A;  1VE2 A;  1WYZ A;  2E8R A;  3ND1 A;  2HUQ A;  2P5C A;  2ENI A;  2E8H A;  2EMU A;  2ELD A;  2DV7 A;  2EGS A;  2PCH A;  2PCA A;  1WDE A;  2P6I A;  2EL0 A;  1VA0 A;  2E0K A;  2P6L A;  2EL2 A;  4E16 A;  2P5F A;  1PJQ A;  2DV5 A;  2EGL A;  2E08 A;  2YBO A;  2EJZ A;  2EKA A;  2OWF A;  2HUX A;  2HR8 A;  2E8Q A;  2E16 A;  2EGB A;  2EK7 A;  2BB3 A;  1PJS A;  2ED3 A;  2PB6 A;  1V9A A;  5HW4 A;  2EH5 A;  3NDC A;  2PCM A;  2OWV A;  2DV3 A;  3NUT A;  2EEQ A;  2OWK A;  2ZVC A;  1S4D A;  3FQ6 A;  2OWU A;  2EH2 A;  2EL3 A;  1VHV A;  2OWG A;  2DV4 A;  2DSG A;  1VCE A;  2E8S A;  2E0N A;  2EK4 A;  2DXW A;  2NPN A;  2PCK A;  2EK2 A;  2YBQ A;  3KWP A;  2E07 A;  2DXV A;  3HH1 A;  2EN5 A;  2DEK A;  3FFY A;  2EJK A;  2HUV A;  2PB4 A;  2QBU A;  2DSH A;  2ELE A;  1CBF A;  2DSI A;  2E4N A;  2EHL A;  2P6D A;  2EJJ A;  1PJT A; 
#chains in the Genus database with same CATH topology
 3I4T A;  2EH4 A;  2E17 A;  3UV3 A;  4N7B A;  2P9D A;  3T0F A;  2E4R A;  1WNG A;  3UV7 A;  2CBF A;  3T0G A;  2EMR A;  2PB5 A;  2ED5 A;  2P6K A;  3TIX B;  3UWM A;  2DXX A;  2EHC A;  2PCG A;  2PCI A;  2P2X A;  2E7R A;  2HUT A;  2E15 A;  3NEI A;  2ZVB A;  4MUY A;  2EK3 A;  2EL1 A;  2Z6R A;  1VE2 A;  1WYZ A;  2E8R A;  3ND1 A;  2HUQ A;  3SZL A;  2P5C A;  3ZGL A;  4H4D A;  2ENI A;  2E8H A;  2EMU A;  2ELD A;  3UTD A;  2DV7 A;  2EGS A;  2PCH A;  2PCA A;  1WDE A;  2P6I A;  2EL0 A;  1VA0 A;  2E0K A;  4H4C A;  3KE8 A;  3KEM A;  2P6L A;  4MV5 A;  2EL2 A;  4E16 A;  3F7T A;  4MUX A;  2P5F A;  1PJQ A;  3KEL A;  2DV5 A;  2EGL A;  2E08 A;  2YBO A;  3URK A;  3KEF A;  2EJZ A;  2EKA A;  2OWF A;  2HUX A;  3SZU A;  2HR8 A;  2E8Q A;  2E16 A;  2EGB A;  2EK7 A;  2BB3 A;  1PJS A;  2ED3 A;  2PB6 A;  1V9A A;  4H4E A;  5HW4 A;  2EH5 A;  3NDC A;  2PCM A;  2OWV A;  2DV3 A;  3NUT A;  2EEQ A;  2OWK A;  2ZVC A;  1S4D A;  3FQ6 A;  2OWU A;  2EH2 A;  2EL3 A;  1VHV A;  2OWG A;  2DV4 A;  2DSG A;  1VCE A;  2E8S A;  3LMM A;  2E0N A;  2EK4 A;  4MV0 A;  2DXW A;  2NPN A;  3DNF A;  4EB3 A;  3SZO A;  2PCK A;  2EK2 A;  2YBQ A;  3KWP A;  2E07 A;  2DXV A;  2KYY A;  3HH1 A;  3UV6 A;  2EN5 A;  3ZGN A;  2DEK A;  3FFY A;  2EJK A;  3UTC A;  2HUV A;  2PB4 A;  2QBU A;  2DSH A;  2ELE A;  3KE9 A;  1CBF A;  2DSI A;  2E4N A;  2EHL A;  2P6D A;  2EJJ A;  1PJT A; 
#chains in the Genus database with same CATH homology
 3I4T A;  2EH4 A;  2E17 A;  3UV3 A;  4N7B A;  2P9D A;  3T0F A;  2E4R A;  1WNG A;  3UV7 A;  2CBF A;  3T0G A;  2EMR A;  2PB5 A;  2ED5 A;  2P6K A;  3TIX B;  3UWM A;  2DXX A;  2EHC A;  2PCG A;  2PCI A;  2P2X A;  2E7R A;  2HUT A;  2E15 A;  3NEI A;  2ZVB A;  4MUY A;  2EK3 A;  2EL1 A;  2Z6R A;  1VE2 A;  1WYZ A;  2E8R A;  3ND1 A;  2HUQ A;  3SZL A;  2P5C A;  3ZGL A;  4H4D A;  2ENI A;  2E8H A;  2EMU A;  2ELD A;  3UTD A;  2DV7 A;  2EGS A;  2PCH A;  2PCA A;  1WDE A;  2P6I A;  2EL0 A;  1VA0 A;  2E0K A;  4H4C A;  3KE8 A;  3KEM A;  2P6L A;  4MV5 A;  2EL2 A;  4E16 A;  3F7T A;  4MUX A;  2P5F A;  1PJQ A;  3KEL A;  2DV5 A;  2EGL A;  2E08 A;  2YBO A;  3URK A;  3KEF A;  2EJZ A;  2EKA A;  2OWF A;  2HUX A;  3SZU A;  2HR8 A;  2E8Q A;  2E16 A;  2EGB A;  2EK7 A;  2BB3 A;  1PJS A;  2ED3 A;  2PB6 A;  1V9A A;  4H4E A;  5HW4 A;  2EH5 A;  3NDC A;  2PCM A;  2OWV A;  2DV3 A;  3NUT A;  2EEQ A;  2OWK A;  2ZVC A;  1S4D A;  3FQ6 A;  2OWU A;  2EH2 A;  2EL3 A;  1VHV A;  2OWG A;  2DV4 A;  2DSG A;  1VCE A;  2E8S A;  3LMM A;  2E0N A;  2EK4 A;  4MV0 A;  2DXW A;  2NPN A;  3DNF A;  4EB3 A;  3SZO A;  2PCK A;  2EK2 A;  2YBQ A;  3KWP A;  2E07 A;  2DXV A;  2KYY A;  3HH1 A;  3UV6 A;  2EN5 A;  3ZGN A;  2DEK A;  3FFY A;  2EJK A;  3UTC A;  2HUV A;  2PB4 A;  2QBU A;  2DSH A;  2ELE A;  3KE9 A;  1CBF A;  2DSI A;  2E4N A;  2EHL A;  2P6D A;  2EJJ A;  1PJT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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