2EHLA

Crystal structure of thr146 to arg mutant of diphthine synthase
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
265
structure length
265
Chain Sequence
b'MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPRSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords diphthine synthase
publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
total genus 86
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2007-03-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2ehlA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2ehlA01
1VA0A 2DSGA 2EK3A 2P6DA 2OWKA 2EMRA 3ND1A 2ENIA 2HUVA 1VE2A 2EK4A 2OWVA 2EJKA 2DXXA 2EHCA 2E4NA 2EL3A 2EL0A 2EL1A 1PJQA 2YBOA 2ED3A 1V9AA 2DV4A 1VHVA 2PB6A 1WNGA 2PCAA 3FFYA 2Z6RA 2DSHA 3FQ6A 3NEIA 2E8HA 2DV3A 2E08A 3NUTA 2BB3A 2ED5A 2E0KA 2HUTA 2E4RA 2DV7A 2P5CA 2HR8A 1S4DA 1PJSA 2E8RA 2EK7A 1WDEA 4E16A 2P6LA 2EH5A 2PCHA 2E07A 3HH1A 2PCMA 3KWPA 2EGBA 5HW4A 2EEQA 2NPNA 2EHLA 2PB4A 2EMUA 2E0NA 2EKAA 2P5FA 2EJZA 2OWFA 2ELEA 2EN5A 3NDCA 2PCIA 2QBUA 2P9DA 2PCGA 2YBQA 2P6KA 2ZVCA 2E16A 2P2XA 2EL2A 2DSIA 2ZVBA 2DEKA 1VCEA 2E17A 2EGSA 2E15A 2EK2A 1CBFA 2OWGA 2EJJA 2E7RA 2HUXA 2CBFA 2PCKA 2DV5A 2E8QA 2PB5A 2DXWA 2P6IA 1WYZA 2EH2A 2EH4A 2HUQA 2ELDA 2E8SA 2DXVA 3I4TA 1PJTA 2OWUA 2EGLA
chains in the Genus database with same CATH superfamily
4N7BA 1VA0A 2DSGA 4H4DA 2EK3A 2P6DA 2OWKA 2EMRA 3ND1A 2ENIA 2HUVA 1VE2A 2EK4A 2OWVA 2EJKA 2DXXA 3SZOA 2EHCA 2E4NA 3ZGLA 2EL3A 3URKA 2EL0A 2EL1A 4MUXA 1PJQA 2YBOA 2ED3A 1V9AA 2DV4A 3UV7A 3UWMA 3ZGNA 3LMMA 1VHVA 2PB6A 1WNGA 2PCAA 3FFYA 2Z6RA 2KYYA 2DSHA 3FQ6A 3NEIA 2E8HA 2DV3A 2E08A 3NUTA 2BB3A 2ED5A 2E0KA 2HUTA 4MUYA 2E4RA 2DV7A 2P5CA 2HR8A 1S4DA 3KEMA 3UTCA 1PJSA 2E8RA 2EK7A 4H4EA 1WDEA 4E16A 2P6LA 3SZLA 2EH5A 2PCHA 2E07A 3HH1A 2PCMA 3KWPA 2EGBA 5HW4A 2EEQA 2NPNA 2EHLA 2PB4A 2EMUA 2E0NA 2EKAA 2P5FA 2EJZA 3DNFA 2OWFA 3KELA 2ELEA 2EN5A 3NDCA 2PCIA 2QBUA 2P9DA 4MV0A 4EB3A 2PCGA 2YBQA 2P6KA 2ZVCA 2E16A 2P2XA 2EL2A 3UTDA 2DSIA 2ZVBA 2DEKA 1VCEA 2E17A 2EGSA 2E15A 3TIXB 3KE9A 2EK2A 4H4CA 3UV6A 1CBFA 3KEFA 2OWGA 2EJJA 3T0GA 2E7RA 3SZUA 2HUXA 3KE8A 3UV3A 3T0FA 2CBFA 3F7TA 2PCKA 2DV5A 2E8QA 2PB5A 2DXWA 2P6IA 1WYZA 2EH2A 2EH4A 2HUQA 2ELDA 4MV5A 2E8SA 2DXVA 3I4TA 1PJTA 2OWUA 2EGLA
chains in the Genus database with same CATH topology
4N7BA 1VA0A 2DSGA 4H4DA 2EK3A 2P6DA 2OWKA 2EMRA 3ND1A 2ENIA 2HUVA 1VE2A 2EK4A 2OWVA 2EJKA 2DXXA 3SZOA 2EHCA 2E4NA 3ZGLA 2EL3A 3URKA 2EL0A 2EL1A 4MUXA 1PJQA 2YBOA 2ED3A 1V9AA 2DV4A 3UV7A 3UWMA 3ZGNA 3LMMA 1VHVA 2PB6A 1WNGA 2PCAA 3FFYA 2Z6RA 2KYYA 2DSHA 3FQ6A 3NEIA 2E8HA 2DV3A 2E08A 3NUTA 2BB3A 2ED5A 2E0KA 2HUTA 4MUYA 2E4RA 2DV7A 2P5CA 2HR8A 1S4DA 3KEMA 3UTCA 1PJSA 2E8RA 2EK7A 4H4EA 1WDEA 4E16A 2P6LA 3SZLA 2EH5A 2PCHA 2E07A 3HH1A 2PCMA 3KWPA 2EGBA 5HW4A 2EEQA 2NPNA 2EHLA 2PB4A 2EMUA 2E0NA 2EKAA 2P5FA 2EJZA 3DNFA 2OWFA 3KELA 2ELEA 2EN5A 3NDCA 2PCIA 2QBUA 2P9DA 4MV0A 4EB3A 2PCGA 2YBQA 2P6KA 2ZVCA 2E16A 2P2XA 2EL2A 3UTDA 2DSIA 2ZVBA 2DEKA 1VCEA 2E17A 2EGSA 2E15A 3TIXB 3KE9A 2EK2A 4H4CA 3UV6A 1CBFA 3KEFA 2OWGA 2EJJA 3T0GA 2E7RA 3SZUA 2HUXA 3KE8A 3UV3A 3T0FA 2CBFA 3F7TA 2PCKA 2DV5A 2E8QA 2PB5A 2DXWA 2P6IA 1WYZA 2EH2A 2EH4A 2HUQA 2ELDA 4MV5A 2E8SA 2DXVA 3I4TA 1PJTA 2OWUA 2EGLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VA0 A;  2DSG A;  2EK3 A;  2P6D A;  2OWK A;  2EMR A;  3ND1 A;  2ENI A;  2HUV A;  1VE2 A;  2EK4 A;  2OWV A;  2EJK A;  2DXX A;  2EHC A;  2E4N A;  2EL3 A;  2EL0 A;  2EL1 A;  1PJQ A;  2YBO A;  2ED3 A;  1V9A A;  2DV4 A;  1VHV A;  2PB6 A;  1WNG A;  2PCA A;  3FFY A;  2Z6R A;  2DSH A;  3FQ6 A;  3NEI A;  2E8H A;  2DV3 A;  2E08 A;  3NUT A;  2BB3 A;  2ED5 A;  2E0K A;  2HUT A;  2E4R A;  2DV7 A;  2P5C A;  2HR8 A;  1S4D A;  1PJS A;  2E8R A;  2EK7 A;  1WDE A;  4E16 A;  2P6L A;  2EH5 A;  2PCH A;  2E07 A;  3HH1 A;  2PCM A;  3KWP A;  2EGB A;  5HW4 A;  2EEQ A;  2NPN A;  2EHL A;  2PB4 A;  2EMU A;  2E0N A;  2EKA A;  2P5F A;  2EJZ A;  2OWF A;  2ELE A;  2EN5 A;  3NDC A;  2PCI A;  2QBU A;  2P9D A;  2PCG A;  2YBQ A;  2P6K A;  2ZVC A;  2E16 A;  2P2X A;  2EL2 A;  2DSI A;  2ZVB A;  2DEK A;  1VCE A;  2E17 A;  2EGS A;  2E15 A;  2EK2 A;  1CBF A;  2OWG A;  2EJJ A;  2E7R A;  2HUX A;  2CBF A;  2PCK A;  2DV5 A;  2E8Q A;  2PB5 A;  2DXW A;  2P6I A;  1WYZ A;  2EH2 A;  2EH4 A;  2HUQ A;  2ELD A;  2E8S A;  2DXV A;  3I4T A;  1PJT A;  2OWU A;  2EGL A; 
#chains in the Genus database with same CATH topology
 4N7B A;  1VA0 A;  2DSG A;  4H4D A;  2EK3 A;  2P6D A;  2OWK A;  2EMR A;  3ND1 A;  2ENI A;  2HUV A;  1VE2 A;  2EK4 A;  2OWV A;  2EJK A;  2DXX A;  3SZO A;  2EHC A;  2E4N A;  3ZGL A;  2EL3 A;  3URK A;  2EL0 A;  2EL1 A;  4MUX A;  1PJQ A;  2YBO A;  2ED3 A;  1V9A A;  2DV4 A;  3UV7 A;  3UWM A;  3ZGN A;  3LMM A;  1VHV A;  2PB6 A;  1WNG A;  2PCA A;  3FFY A;  2Z6R A;  2KYY A;  2DSH A;  3FQ6 A;  3NEI A;  2E8H A;  2DV3 A;  2E08 A;  3NUT A;  2BB3 A;  2ED5 A;  2E0K A;  2HUT A;  4MUY A;  2E4R A;  2DV7 A;  2P5C A;  2HR8 A;  1S4D A;  3KEM A;  3UTC A;  1PJS A;  2E8R A;  2EK7 A;  4H4E A;  1WDE A;  4E16 A;  2P6L A;  3SZL A;  2EH5 A;  2PCH A;  2E07 A;  3HH1 A;  2PCM A;  3KWP A;  2EGB A;  5HW4 A;  2EEQ A;  2NPN A;  2EHL A;  2PB4 A;  2EMU A;  2E0N A;  2EKA A;  2P5F A;  2EJZ A;  3DNF A;  2OWF A;  3KEL A;  2ELE A;  2EN5 A;  3NDC A;  2PCI A;  2QBU A;  2P9D A;  4MV0 A;  4EB3 A;  2PCG A;  2YBQ A;  2P6K A;  2ZVC A;  2E16 A;  2P2X A;  2EL2 A;  3UTD A;  2DSI A;  2ZVB A;  2DEK A;  1VCE A;  2E17 A;  2EGS A;  2E15 A;  3TIX B;  3KE9 A;  2EK2 A;  4H4C A;  3UV6 A;  1CBF A;  3KEF A;  2OWG A;  2EJJ A;  3T0G A;  2E7R A;  3SZU A;  2HUX A;  3KE8 A;  3UV3 A;  3T0F A;  2CBF A;  3F7T A;  2PCK A;  2DV5 A;  2E8Q A;  2PB5 A;  2DXW A;  2P6I A;  1WYZ A;  2EH2 A;  2EH4 A;  2HUQ A;  2ELD A;  4MV5 A;  2E8S A;  2DXV A;  3I4T A;  1PJT A;  2OWU A;  2EGL A; 
#chains in the Genus database with same CATH homology
 4N7B A;  1VA0 A;  2DSG A;  4H4D A;  2EK3 A;  2P6D A;  2OWK A;  2EMR A;  3ND1 A;  2ENI A;  2HUV A;  1VE2 A;  2EK4 A;  2OWV A;  2EJK A;  2DXX A;  3SZO A;  2EHC A;  2E4N A;  3ZGL A;  2EL3 A;  3URK A;  2EL0 A;  2EL1 A;  4MUX A;  1PJQ A;  2YBO A;  2ED3 A;  1V9A A;  2DV4 A;  3UV7 A;  3UWM A;  3ZGN A;  3LMM A;  1VHV A;  2PB6 A;  1WNG A;  2PCA A;  3FFY A;  2Z6R A;  2KYY A;  2DSH A;  3FQ6 A;  3NEI A;  2E8H A;  2DV3 A;  2E08 A;  3NUT A;  2BB3 A;  2ED5 A;  2E0K A;  2HUT A;  4MUY A;  2E4R A;  2DV7 A;  2P5C A;  2HR8 A;  1S4D A;  3KEM A;  3UTC A;  1PJS A;  2E8R A;  2EK7 A;  4H4E A;  1WDE A;  4E16 A;  2P6L A;  3SZL A;  2EH5 A;  2PCH A;  2E07 A;  3HH1 A;  2PCM A;  3KWP A;  2EGB A;  5HW4 A;  2EEQ A;  2NPN A;  2EHL A;  2PB4 A;  2EMU A;  2E0N A;  2EKA A;  2P5F A;  2EJZ A;  3DNF A;  2OWF A;  3KEL A;  2ELE A;  2EN5 A;  3NDC A;  2PCI A;  2QBU A;  2P9D A;  4MV0 A;  4EB3 A;  2PCG A;  2YBQ A;  2P6K A;  2ZVC A;  2E16 A;  2P2X A;  2EL2 A;  3UTD A;  2DSI A;  2ZVB A;  2DEK A;  1VCE A;  2E17 A;  2EGS A;  2E15 A;  3TIX B;  3KE9 A;  2EK2 A;  4H4C A;  3UV6 A;  1CBF A;  3KEF A;  2OWG A;  2EJJ A;  3T0G A;  2E7R A;  3SZU A;  2HUX A;  3KE8 A;  3UV3 A;  3T0F A;  2CBF A;  3F7T A;  2PCK A;  2DV5 A;  2E8Q A;  2PB5 A;  2DXW A;  2P6I A;  1WYZ A;  2EH2 A;  2EH4 A;  2HUQ A;  2ELD A;  4MV5 A;  2E8S A;  2DXV A;  3I4T A;  1PJT A;  2OWU A;  2EGL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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