2EMRA

Mutant l65m structure of ph0725 from pyrococcus horikoshii ot3
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVEMNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutant L65M structure of PH0725 from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords Probable diphthine synthase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2007-03-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2emrA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2emrA01
2EHCA 2DXXA 2PB4A 3FQ6A 2EEQA 2EK4A 2EGBA 2DXVA 1S4DA 2PCMA 2YBQA 3NDCA 2EJZA 3ND1A 2DSGA 2BB3A 2P5CA 2E07A 2P9DA 1V9AA 2EL2A 2PCHA 2Z6RA 2DV7A 2DSHA 2ELDA 1WYZA 2DV3A 1VCEA 2E08A 3I4TA 2EJJA 2EGSA 2EL3A 2EKAA 2HUQA 1PJQA 2PCKA 2HUVA 2DEKA 2P2XA 1VA0A 2EK2A 1PJSA 2E4RA 2ELEA 4E16A 2NPNA 2DSIA 2E8HA 2E17A 2OWVA 2E8SA 2PCAA 2E16A 2HR8A 1WNGA 2HUTA 2P6IA 3NUTA 2HUXA 3FFYA 2E4NA 1CBFA 2EK3A 2ENIA 2OWGA 2E15A 2ZVBA 2QBUA 2E7RA 2EH5A 5HW4A 2PB6A 2E0KA 1VHVA 3NEIA 2P5FA 2EGLA 2PB5A 1VE2A 2E8RA 2EL0A 2P6DA 1WDEA 2EMRA 3KWPA 2DV4A 2P6KA 2CBFA 2ED3A 2YBOA 2OWUA 2EJKA 2E0NA 2P6LA 2OWKA 2PCIA 1PJTA 2EH4A 2ED5A 2EK7A 2DXWA 2OWFA 2EH2A 2EHLA 3HH1A 2ZVCA 2DV5A 2EMUA 2EN5A 2EL1A 2E8QA 2PCGA
chains in the Genus database with same CATH superfamily
2EHCA 2DXXA 2PB4A 3FQ6A 3UV7A 2EEQA 2EK4A 2EGBA 2DXVA 3URKA 1S4DA 2PCMA 2YBQA 3NDCA 2EJZA 3ND1A 2DSGA 2BB3A 2P5CA 2E07A 2P9DA 1V9AA 2EL2A 2PCHA 2Z6RA 3SZLA 3ZGNA 2DV7A 2DSHA 4MUYA 2ELDA 1WYZA 2DV3A 1VCEA 3KE8A 2E08A 3KELA 3I4TA 2EJJA 2EGSA 2EL3A 2EKAA 2HUQA 1PJQA 2PCKA 2HUVA 3F7TA 2DEKA 4N7BA 4H4CA 2P2XA 1VA0A 2EK2A 1PJSA 2E4RA 2ELEA 4E16A 2NPNA 2DSIA 2E8HA 2E17A 2OWVA 2E8SA 2PCAA 2E16A 2HR8A 1WNGA 2HUTA 2P6IA 3NUTA 2HUXA 3FFYA 4H4DA 2E4NA 2KYYA 1CBFA 2EK3A 2ENIA 2OWGA 3LMMA 3UWMA 2E15A 2ZVBA 2QBUA 2E7RA 2EH5A 5HW4A 3UTDA 2PB6A 2E0KA 1VHVA 3NEIA 2P5FA 2EGLA 2PB5A 1VE2A 2E8RA 2EL0A 3UV6A 4EB3A 2P6DA 1WDEA 2EMRA 3ZGLA 3KEMA 4MV5A 3SZOA 3KWPA 3SZUA 2DV4A 2P6KA 2CBFA 2ED3A 3UTCA 2YBOA 2OWUA 2EJKA 4MUXA 4H4EA 2E0NA 4MV0A 2P6LA 2OWKA 2PCIA 1PJTA 2EH4A 3T0FA 2ED5A 2EK7A 2DXWA 3TIXB 2OWFA 2EH2A 2EHLA 3HH1A 3DNFA 2ZVCA 2DV5A 2EMUA 2EN5A 3KE9A 2EL1A 3UV3A 2E8QA 3KEFA 2PCGA 3T0GA
chains in the Genus database with same CATH topology
2EHCA 2DXXA 2PB4A 3FQ6A 3UV7A 2EEQA 2EK4A 2EGBA 2DXVA 3URKA 1S4DA 2PCMA 2YBQA 3NDCA 2EJZA 3ND1A 2DSGA 2BB3A 2P5CA 2E07A 2P9DA 1V9AA 2EL2A 2PCHA 2Z6RA 3SZLA 3ZGNA 2DV7A 2DSHA 4MUYA 2ELDA 1WYZA 2DV3A 1VCEA 3KE8A 2E08A 3KELA 3I4TA 2EJJA 2EGSA 2EL3A 2EKAA 2HUQA 1PJQA 2PCKA 2HUVA 3F7TA 2DEKA 4N7BA 4H4CA 2P2XA 1VA0A 2EK2A 1PJSA 2E4RA 2ELEA 4E16A 2NPNA 2DSIA 2E8HA 2E17A 2OWVA 2E8SA 2PCAA 2E16A 2HR8A 1WNGA 2HUTA 2P6IA 3NUTA 2HUXA 3FFYA 4H4DA 2E4NA 2KYYA 1CBFA 2EK3A 2ENIA 2OWGA 3LMMA 3UWMA 2E15A 2ZVBA 2QBUA 2E7RA 2EH5A 5HW4A 3UTDA 2PB6A 2E0KA 1VHVA 3NEIA 2P5FA 2EGLA 2PB5A 1VE2A 2E8RA 2EL0A 3UV6A 4EB3A 2P6DA 1WDEA 2EMRA 3ZGLA 3KEMA 4MV5A 3SZOA 3KWPA 3SZUA 2DV4A 2P6KA 2CBFA 2ED3A 3UTCA 2YBOA 2OWUA 2EJKA 4MUXA 4H4EA 2E0NA 4MV0A 2P6LA 2OWKA 2PCIA 1PJTA 2EH4A 3T0FA 2ED5A 2EK7A 2DXWA 3TIXB 2OWFA 2EH2A 2EHLA 3HH1A 3DNFA 2ZVCA 2DV5A 2EMUA 2EN5A 3KE9A 2EL1A 3UV3A 2E8QA 3KEFA 2PCGA 3T0GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EHC A;  2DXX A;  2PB4 A;  3FQ6 A;  2EEQ A;  2EK4 A;  2EGB A;  2DXV A;  1S4D A;  2PCM A;  2YBQ A;  3NDC A;  2EJZ A;  3ND1 A;  2DSG A;  2BB3 A;  2P5C A;  2E07 A;  2P9D A;  1V9A A;  2EL2 A;  2PCH A;  2Z6R A;  2DV7 A;  2DSH A;  2ELD A;  1WYZ A;  2DV3 A;  1VCE A;  2E08 A;  3I4T A;  2EJJ A;  2EGS A;  2EL3 A;  2EKA A;  2HUQ A;  1PJQ A;  2PCK A;  2HUV A;  2DEK A;  2P2X A;  1VA0 A;  2EK2 A;  1PJS A;  2E4R A;  2ELE A;  4E16 A;  2NPN A;  2DSI A;  2E8H A;  2E17 A;  2OWV A;  2E8S A;  2PCA A;  2E16 A;  2HR8 A;  1WNG A;  2HUT A;  2P6I A;  3NUT A;  2HUX A;  3FFY A;  2E4N A;  1CBF A;  2EK3 A;  2ENI A;  2OWG A;  2E15 A;  2ZVB A;  2QBU A;  2E7R A;  2EH5 A;  5HW4 A;  2PB6 A;  2E0K A;  1VHV A;  3NEI A;  2P5F A;  2EGL A;  2PB5 A;  1VE2 A;  2E8R A;  2EL0 A;  2P6D A;  1WDE A;  2EMR A;  3KWP A;  2DV4 A;  2P6K A;  2CBF A;  2ED3 A;  2YBO A;  2OWU A;  2EJK A;  2E0N A;  2P6L A;  2OWK A;  2PCI A;  1PJT A;  2EH4 A;  2ED5 A;  2EK7 A;  2DXW A;  2OWF A;  2EH2 A;  2EHL A;  3HH1 A;  2ZVC A;  2DV5 A;  2EMU A;  2EN5 A;  2EL1 A;  2E8Q A;  2PCG A; 
#chains in the Genus database with same CATH topology
 2EHC A;  2DXX A;  2PB4 A;  3FQ6 A;  3UV7 A;  2EEQ A;  2EK4 A;  2EGB A;  2DXV A;  3URK A;  1S4D A;  2PCM A;  2YBQ A;  3NDC A;  2EJZ A;  3ND1 A;  2DSG A;  2BB3 A;  2P5C A;  2E07 A;  2P9D A;  1V9A A;  2EL2 A;  2PCH A;  2Z6R A;  3SZL A;  3ZGN A;  2DV7 A;  2DSH A;  4MUY A;  2ELD A;  1WYZ A;  2DV3 A;  1VCE A;  3KE8 A;  2E08 A;  3KEL A;  3I4T A;  2EJJ A;  2EGS A;  2EL3 A;  2EKA A;  2HUQ A;  1PJQ A;  2PCK A;  2HUV A;  3F7T A;  2DEK A;  4N7B A;  4H4C A;  2P2X A;  1VA0 A;  2EK2 A;  1PJS A;  2E4R A;  2ELE A;  4E16 A;  2NPN A;  2DSI A;  2E8H A;  2E17 A;  2OWV A;  2E8S A;  2PCA A;  2E16 A;  2HR8 A;  1WNG A;  2HUT A;  2P6I A;  3NUT A;  2HUX A;  3FFY A;  4H4D A;  2E4N A;  2KYY A;  1CBF A;  2EK3 A;  2ENI A;  2OWG A;  3LMM A;  3UWM A;  2E15 A;  2ZVB A;  2QBU A;  2E7R A;  2EH5 A;  5HW4 A;  3UTD A;  2PB6 A;  2E0K A;  1VHV A;  3NEI A;  2P5F A;  2EGL A;  2PB5 A;  1VE2 A;  2E8R A;  2EL0 A;  3UV6 A;  4EB3 A;  2P6D A;  1WDE A;  2EMR A;  3ZGL A;  3KEM A;  4MV5 A;  3SZO A;  3KWP A;  3SZU A;  2DV4 A;  2P6K A;  2CBF A;  2ED3 A;  3UTC A;  2YBO A;  2OWU A;  2EJK A;  4MUX A;  4H4E A;  2E0N A;  4MV0 A;  2P6L A;  2OWK A;  2PCI A;  1PJT A;  2EH4 A;  3T0F A;  2ED5 A;  2EK7 A;  2DXW A;  3TIX B;  2OWF A;  2EH2 A;  2EHL A;  3HH1 A;  3DNF A;  2ZVC A;  2DV5 A;  2EMU A;  2EN5 A;  3KE9 A;  2EL1 A;  3UV3 A;  2E8Q A;  3KEF A;  2PCG A;  3T0G A; 
#chains in the Genus database with same CATH homology
 2EHC A;  2DXX A;  2PB4 A;  3FQ6 A;  3UV7 A;  2EEQ A;  2EK4 A;  2EGB A;  2DXV A;  3URK A;  1S4D A;  2PCM A;  2YBQ A;  3NDC A;  2EJZ A;  3ND1 A;  2DSG A;  2BB3 A;  2P5C A;  2E07 A;  2P9D A;  1V9A A;  2EL2 A;  2PCH A;  2Z6R A;  3SZL A;  3ZGN A;  2DV7 A;  2DSH A;  4MUY A;  2ELD A;  1WYZ A;  2DV3 A;  1VCE A;  3KE8 A;  2E08 A;  3KEL A;  3I4T A;  2EJJ A;  2EGS A;  2EL3 A;  2EKA A;  2HUQ A;  1PJQ A;  2PCK A;  2HUV A;  3F7T A;  2DEK A;  4N7B A;  4H4C A;  2P2X A;  1VA0 A;  2EK2 A;  1PJS A;  2E4R A;  2ELE A;  4E16 A;  2NPN A;  2DSI A;  2E8H A;  2E17 A;  2OWV A;  2E8S A;  2PCA A;  2E16 A;  2HR8 A;  1WNG A;  2HUT A;  2P6I A;  3NUT A;  2HUX A;  3FFY A;  4H4D A;  2E4N A;  2KYY A;  1CBF A;  2EK3 A;  2ENI A;  2OWG A;  3LMM A;  3UWM A;  2E15 A;  2ZVB A;  2QBU A;  2E7R A;  2EH5 A;  5HW4 A;  3UTD A;  2PB6 A;  2E0K A;  1VHV A;  3NEI A;  2P5F A;  2EGL A;  2PB5 A;  1VE2 A;  2E8R A;  2EL0 A;  3UV6 A;  4EB3 A;  2P6D A;  1WDE A;  2EMR A;  3ZGL A;  3KEM A;  4MV5 A;  3SZO A;  3KWP A;  3SZU A;  2DV4 A;  2P6K A;  2CBF A;  2ED3 A;  3UTC A;  2YBO A;  2OWU A;  2EJK A;  4MUX A;  4H4E A;  2E0N A;  4MV0 A;  2P6L A;  2OWK A;  2PCI A;  1PJT A;  2EH4 A;  3T0F A;  2ED5 A;  2EK7 A;  2DXW A;  3TIX B;  2OWF A;  2EH2 A;  2EHL A;  3HH1 A;  3DNF A;  2ZVC A;  2DV5 A;  2EMU A;  2EN5 A;  3KE9 A;  2EL1 A;  3UV3 A;  2E8Q A;  3KEF A;  2PCG A;  3T0G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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