2EN5A

Mutant r262h structure of ph0725 from pyrococcus horikoshii ot3
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILHVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutant R262H structure of PH0725 from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 85
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2007-03-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2en5A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2en5A01
2PCGA 1V9AA 2P2XA 2EHCA 5HW4A 1VHVA 2PCIA 2EMRA 2QBUA 2ZVBA 1WNGA 2EGBA 2HUXA 2EL1A 2EL0A 2EJJA 2E16A 2CBFA 1S4DA 2EJKA 2EMUA 2DSIA 2DV3A 2DSGA 2EH4A 2DSHA 2E08A 1VA0A 2DV4A 1PJSA 2P6DA 2OWFA 2OWGA 3KWPA 4E16A 2PCKA 2P6IA 1VCEA 2OWKA 2E8SA 2E4RA 2EKAA 2P6KA 2DXVA 2EH2A 2EL2A 2OWVA 2PB4A 2PB6A 2E15A 2EJZA 1PJQA 1CBFA 2E0KA 3ND1A 2HR8A 2NPNA 2E8RA 2EGSA 1PJTA 2ELDA 1VE2A 2P5FA 2DV7A 3NEIA 2P6LA 3FFYA 2ED3A 2ENIA 2E17A 2DXXA 2EK7A 2PB5A 2HUTA 2ZVCA 2EH5A 2E8HA 2EEQA 2OWUA 2E7RA 2DXWA 2EK3A 1WDEA 3NDCA 2EGLA 3HH1A 2E8QA 3I4TA 2EK2A 2PCAA 2ED5A 3FQ6A 3NUTA 1WYZA 2DEKA 2YBOA 2EL3A 2EN5A 2DV5A 2E07A 2P5CA 2EHLA 2ELEA 2E0NA 2HUQA 2PCMA 2HUVA 2YBQA 2EK4A 2PCHA 2Z6RA 2BB3A 2E4NA 2P9DA
chains in the Genus database with same CATH superfamily
2PCGA 1V9AA 3UV3A 2P2XA 2EHCA 5HW4A 1VHVA 2PCIA 2EMRA 2QBUA 2ZVBA 1WNGA 2EGBA 4MUYA 2HUXA 3UWMA 2EL1A 4N7BA 2EL0A 2EJJA 2E16A 2CBFA 1S4DA 2EJKA 2EMUA 2DSIA 3KEMA 2DV3A 2DSGA 3SZLA 2EH4A 2DSHA 4MV5A 2E08A 1VA0A 2DV4A 4MV0A 3KEFA 1PJSA 2P6DA 2OWFA 2OWGA 3SZOA 4H4DA 3KWPA 4E16A 2PCKA 2P6IA 3KE9A 1VCEA 2OWKA 2E8SA 2E4RA 3F7TA 2EKAA 2P6KA 3LMMA 2DXVA 2EH2A 2EL2A 2OWVA 2PB4A 2PB6A 2E15A 2EJZA 3KELA 1PJQA 1CBFA 2E0KA 3ND1A 2HR8A 4H4CA 2NPNA 2E8RA 2EGSA 1PJTA 2ELDA 1VE2A 2P5FA 2DV7A 3NEIA 3UTDA 2P6LA 3FFYA 2ED3A 2ENIA 2E17A 4EB3A 2DXXA 2EK7A 2PB5A 2HUTA 3T0GA 2ZVCA 2EH5A 2E8HA 3URKA 2KYYA 2EEQA 3ZGLA 2OWUA 2E7RA 3KE8A 3SZUA 3T0FA 4MUXA 2DXWA 2EK3A 1WDEA 3UV6A 3NDCA 2EGLA 3HH1A 2E8QA 3UV7A 3I4TA 2EK2A 2PCAA 2ED5A 3UTCA 3FQ6A 3NUTA 1WYZA 2DEKA 2YBOA 2EL3A 4H4EA 2EN5A 3TIXB 2DV5A 2E07A 2P5CA 2EHLA 2ELEA 3DNFA 2E0NA 2HUQA 2PCMA 2HUVA 2YBQA 3ZGNA 2EK4A 2PCHA 2Z6RA 2BB3A 2E4NA 2P9DA
chains in the Genus database with same CATH topology
2PCGA 1V9AA 3UV3A 2P2XA 2EHCA 5HW4A 1VHVA 2PCIA 2EMRA 2QBUA 2ZVBA 1WNGA 2EGBA 4MUYA 2HUXA 3UWMA 2EL1A 4N7BA 2EL0A 2EJJA 2E16A 2CBFA 1S4DA 2EJKA 2EMUA 2DSIA 3KEMA 2DV3A 2DSGA 3SZLA 2EH4A 2DSHA 4MV5A 2E08A 1VA0A 2DV4A 4MV0A 3KEFA 1PJSA 2P6DA 2OWFA 2OWGA 3SZOA 4H4DA 3KWPA 4E16A 2PCKA 2P6IA 3KE9A 1VCEA 2OWKA 2E8SA 2E4RA 3F7TA 2EKAA 2P6KA 3LMMA 2DXVA 2EH2A 2EL2A 2OWVA 2PB4A 2PB6A 2E15A 2EJZA 3KELA 1PJQA 1CBFA 2E0KA 3ND1A 2HR8A 4H4CA 2NPNA 2E8RA 2EGSA 1PJTA 2ELDA 1VE2A 2P5FA 2DV7A 3NEIA 3UTDA 2P6LA 3FFYA 2ED3A 2ENIA 2E17A 4EB3A 2DXXA 2EK7A 2PB5A 2HUTA 3T0GA 2ZVCA 2EH5A 2E8HA 3URKA 2KYYA 2EEQA 3ZGLA 2OWUA 2E7RA 3KE8A 3SZUA 3T0FA 4MUXA 2DXWA 2EK3A 1WDEA 3UV6A 3NDCA 2EGLA 3HH1A 2E8QA 3UV7A 3I4TA 2EK2A 2PCAA 2ED5A 3UTCA 3FQ6A 3NUTA 1WYZA 2DEKA 2YBOA 2EL3A 4H4EA 2EN5A 3TIXB 2DV5A 2E07A 2P5CA 2EHLA 2ELEA 3DNFA 2E0NA 2HUQA 2PCMA 2HUVA 2YBQA 3ZGNA 2EK4A 2PCHA 2Z6RA 2BB3A 2E4NA 2P9DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PCG A;  1V9A A;  2P2X A;  2EHC A;  5HW4 A;  1VHV A;  2PCI A;  2EMR A;  2QBU A;  2ZVB A;  1WNG A;  2EGB A;  2HUX A;  2EL1 A;  2EL0 A;  2EJJ A;  2E16 A;  2CBF A;  1S4D A;  2EJK A;  2EMU A;  2DSI A;  2DV3 A;  2DSG A;  2EH4 A;  2DSH A;  2E08 A;  1VA0 A;  2DV4 A;  1PJS A;  2P6D A;  2OWF A;  2OWG A;  3KWP A;  4E16 A;  2PCK A;  2P6I A;  1VCE A;  2OWK A;  2E8S A;  2E4R A;  2EKA A;  2P6K A;  2DXV A;  2EH2 A;  2EL2 A;  2OWV A;  2PB4 A;  2PB6 A;  2E15 A;  2EJZ A;  1PJQ A;  1CBF A;  2E0K A;  3ND1 A;  2HR8 A;  2NPN A;  2E8R A;  2EGS A;  1PJT A;  2ELD A;  1VE2 A;  2P5F A;  2DV7 A;  3NEI A;  2P6L A;  3FFY A;  2ED3 A;  2ENI A;  2E17 A;  2DXX A;  2EK7 A;  2PB5 A;  2HUT A;  2ZVC A;  2EH5 A;  2E8H A;  2EEQ A;  2OWU A;  2E7R A;  2DXW A;  2EK3 A;  1WDE A;  3NDC A;  2EGL A;  3HH1 A;  2E8Q A;  3I4T A;  2EK2 A;  2PCA A;  2ED5 A;  3FQ6 A;  3NUT A;  1WYZ A;  2DEK A;  2YBO A;  2EL3 A;  2EN5 A;  2DV5 A;  2E07 A;  2P5C A;  2EHL A;  2ELE A;  2E0N A;  2HUQ A;  2PCM A;  2HUV A;  2YBQ A;  2EK4 A;  2PCH A;  2Z6R A;  2BB3 A;  2E4N A;  2P9D A; 
#chains in the Genus database with same CATH topology
 2PCG A;  1V9A A;  3UV3 A;  2P2X A;  2EHC A;  5HW4 A;  1VHV A;  2PCI A;  2EMR A;  2QBU A;  2ZVB A;  1WNG A;  2EGB A;  4MUY A;  2HUX A;  3UWM A;  2EL1 A;  4N7B A;  2EL0 A;  2EJJ A;  2E16 A;  2CBF A;  1S4D A;  2EJK A;  2EMU A;  2DSI A;  3KEM A;  2DV3 A;  2DSG A;  3SZL A;  2EH4 A;  2DSH A;  4MV5 A;  2E08 A;  1VA0 A;  2DV4 A;  4MV0 A;  3KEF A;  1PJS A;  2P6D A;  2OWF A;  2OWG A;  3SZO A;  4H4D A;  3KWP A;  4E16 A;  2PCK A;  2P6I A;  3KE9 A;  1VCE A;  2OWK A;  2E8S A;  2E4R A;  3F7T A;  2EKA A;  2P6K A;  3LMM A;  2DXV A;  2EH2 A;  2EL2 A;  2OWV A;  2PB4 A;  2PB6 A;  2E15 A;  2EJZ A;  3KEL A;  1PJQ A;  1CBF A;  2E0K A;  3ND1 A;  2HR8 A;  4H4C A;  2NPN A;  2E8R A;  2EGS A;  1PJT A;  2ELD A;  1VE2 A;  2P5F A;  2DV7 A;  3NEI A;  3UTD A;  2P6L A;  3FFY A;  2ED3 A;  2ENI A;  2E17 A;  4EB3 A;  2DXX A;  2EK7 A;  2PB5 A;  2HUT A;  3T0G A;  2ZVC A;  2EH5 A;  2E8H A;  3URK A;  2KYY A;  2EEQ A;  3ZGL A;  2OWU A;  2E7R A;  3KE8 A;  3SZU A;  3T0F A;  4MUX A;  2DXW A;  2EK3 A;  1WDE A;  3UV6 A;  3NDC A;  2EGL A;  3HH1 A;  2E8Q A;  3UV7 A;  3I4T A;  2EK2 A;  2PCA A;  2ED5 A;  3UTC A;  3FQ6 A;  3NUT A;  1WYZ A;  2DEK A;  2YBO A;  2EL3 A;  4H4E A;  2EN5 A;  3TIX B;  2DV5 A;  2E07 A;  2P5C A;  2EHL A;  2ELE A;  3DNF A;  2E0N A;  2HUQ A;  2PCM A;  2HUV A;  2YBQ A;  3ZGN A;  2EK4 A;  2PCH A;  2Z6R A;  2BB3 A;  2E4N A;  2P9D A; 
#chains in the Genus database with same CATH homology
 2PCG A;  1V9A A;  3UV3 A;  2P2X A;  2EHC A;  5HW4 A;  1VHV A;  2PCI A;  2EMR A;  2QBU A;  2ZVB A;  1WNG A;  2EGB A;  4MUY A;  2HUX A;  3UWM A;  2EL1 A;  4N7B A;  2EL0 A;  2EJJ A;  2E16 A;  2CBF A;  1S4D A;  2EJK A;  2EMU A;  2DSI A;  3KEM A;  2DV3 A;  2DSG A;  3SZL A;  2EH4 A;  2DSH A;  4MV5 A;  2E08 A;  1VA0 A;  2DV4 A;  4MV0 A;  3KEF A;  1PJS A;  2P6D A;  2OWF A;  2OWG A;  3SZO A;  4H4D A;  3KWP A;  4E16 A;  2PCK A;  2P6I A;  3KE9 A;  1VCE A;  2OWK A;  2E8S A;  2E4R A;  3F7T A;  2EKA A;  2P6K A;  3LMM A;  2DXV A;  2EH2 A;  2EL2 A;  2OWV A;  2PB4 A;  2PB6 A;  2E15 A;  2EJZ A;  3KEL A;  1PJQ A;  1CBF A;  2E0K A;  3ND1 A;  2HR8 A;  4H4C A;  2NPN A;  2E8R A;  2EGS A;  1PJT A;  2ELD A;  1VE2 A;  2P5F A;  2DV7 A;  3NEI A;  3UTD A;  2P6L A;  3FFY A;  2ED3 A;  2ENI A;  2E17 A;  4EB3 A;  2DXX A;  2EK7 A;  2PB5 A;  2HUT A;  3T0G A;  2ZVC A;  2EH5 A;  2E8H A;  3URK A;  2KYY A;  2EEQ A;  3ZGL A;  2OWU A;  2E7R A;  3KE8 A;  3SZU A;  3T0F A;  4MUX A;  2DXW A;  2EK3 A;  1WDE A;  3UV6 A;  3NDC A;  2EGL A;  3HH1 A;  2E8Q A;  3UV7 A;  3I4T A;  2EK2 A;  2PCA A;  2ED5 A;  3UTC A;  3FQ6 A;  3NUT A;  1WYZ A;  2DEK A;  2YBO A;  2EL3 A;  4H4E A;  2EN5 A;  3TIX B;  2DV5 A;  2E07 A;  2P5C A;  2EHL A;  2ELE A;  3DNF A;  2E0N A;  2HUQ A;  2PCM A;  2HUV A;  2YBQ A;  3ZGN A;  2EK4 A;  2PCH A;  2Z6R A;  2BB3 A;  2E4N A;  2P9D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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