2ETFA

Crystal structure of full length botulinum neurotoxin (type b) light chain
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
437
structure length
431
Chain Sequence
PVTINNFNYNDPIDNNNIIMMEPPFARGTGRYYKAFKITDRIWIIPERYTFGYKPEDFNKSSGIFNRDVEYYDPDYLNTNDKKNIFLQTMIKLFNRIKSKPLGEKLLEMIINGIPYLGDRRVPLEEFNTNIASVTVNKLISNPGEVERKKGIFANLIIFGPGPVLNENETIDIGIQNHFASREGFGGIMQMKFCPEYVSVFNNVQENKGASIFNRRGYFSDPALILMHELIHVLHGLYGIKVDDLPIVPFMQSTDAIQAEELYTFGGQDPSIITPSTDKSIYDKVLQNFRGIVDRLNKVLVCISDPNININIYKNKFKDKYKFVEDSEGKYSIDVESFDKLYKSLMFGFTETNIAENYKIKTRASYFSDSLPPVKIKNLLDNEIYTIEEGFNISDKDMEKEYRGQNKAINKQAYEEISKEHLAVYKIQMCK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of full length botulinum neurotoxin (Type B) light chain
rcsb
molecule tags Hydrolase
source organism Clostridium botulinum
molecule keywords Botulinum neurotoxin B light chain
total genus 132
structure length 431
sequence length 437
chains with identical sequence B
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2005-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01742 Peptidase_M27 Clostridial neurotoxin zinc protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1240.10 Alpha Beta Alpha-Beta Complex Zincin-like Metalloproteases ("zincins"), catalytic domain like 2etfA00
3BWIA 3DS9A 2ETFA 2NYYA 1S0BA 1ZB7A 3C88A 1T3AA 1ZL6A 4ZJXA 2ISGA 4KS6A 4J1LA 2ISHA 3K3QB 1T3CA 3DSEA 3QIYA 1XTFA 2IMAA 3D3XA 1EPWA 1G9AA 3QW6A 1G9DA 5BQNA 3ZURA 3V0AA 3FIEA 1S0DA 3FFZA 4KUFA 3BTAA 3QJ0A 1XTGA 4HEVA 1S0GA 2G7PA 3QW7A 2IMCA 2QN0A 1G9CA 3BONA 2NP0A 2A97A 2IMBA 5BQMA 4ELCA 1I1EA 1ZL5A 2NZ9A 3V0BB 3QIZA 2G7NA 4EL4A 1G9BA 3QIXA 3DDBA 1Z7HA 1ZN3A 3QW5A 4ZKTB 2W2DA 1F82A 2G7QA 1S0EA 1F31A 3C8BA 2FPQA 1YVGA 3BOKA 3C89A 2A8AA 1S0CA 3FIIA 3V0AB 1E1HA 2G7KA 3ZUQA 2ILPA 1ZKWA 3NF3A 1ZKXA 3ZUSA 3QW8A 3BOOA 3C8AA 3VUOA 2XHLA 3DDAA 2ISEA 4KTXA 4EJ5A 1S0FA 3DEBA 3V0BA
chains in the Genus database with same CATH superfamily
3BWIA 3DS9A 2ETFA 2NYYA 1S0BA 1ZB7A 3C88A 2EJQA 1T3AA 1ZL6A 4ZJXA 2ISGA 4KS6A 4J1LA 2ISHA 3K3QB 1T3CA 3DSEA 3QIYA 1XTFA 2IMAA 3D3XA 1EPWA 1G9AA 3QW6A 1G9DA 5BQNA 3ZURA 3V0AA 3FIEA 1S0DA 3FFZA 4KUFA 3BTAA 3QJ0A 1XTGA 4HEVA 3E11A 2YPTA 1S0GA 2G7PA 4AW6A 3QW7A 2IMCA 2QN0A 1G9CA 3BONA 2NP0A 2A97A 2IMBA 5BQMA 4ELCA 4IL3A 1I1EA 1ZL5A 2NZ9A 4QHFA 3V0BB 3QIZA 4KTXA 4EL4A 1G9BA 3QIXA 3DDBA 1Z7HA 4JIUA 1ZN3A 3QW5A 4ZKTB 2W2DA 1F82A 2G7QA 4JIXA 1S0EA 1F31A 3C8BA 2FPQA 1YVGA 3BOKA 3C89A 2A8AA 1S0CA 3FIIA 3V0AB 1E1HA 2G7KA 3ZUQA 2ILPA 1ZKWA 3NF3A 1ZKXA 3ZUSA 3CQBA 3QW8A 3BOOA 3C8AA 3VUOA 2XHLA 3DDAA 2ISEA 2G7NA 4EJ5A 1S0FA 3DEBA 3V0BA
chains in the Genus database with same CATH topology
3BWIA 3DS9A 2ETFA 2NYYA 1S0BA 1ZB7A 3C88A 1T3AA 1ZL6A 4ZJXA 2ISGA 4KS6A 4J1LA 2ISHA 3K3QB 1T3CA 3DSEA 3QIYA 1XTFA 2IMAA 3D3XA 1EPWA 1G9AA 3QW6A 1G9DA 5BQNA 3ZURA 3V0AA 3FIEA 1S0DA 3FFZA 4KUFA 3BTAA 3QJ0A 1XTGA 4HEVA 1S0GA 2G7PA 3QW7A 2IMCA 2QN0A 1G9CA 3BONA 2NP0A 2A97A 2IMBA 5BQMA 4ELCA 1I1EA 1ZL5A 2NZ9A 3V0BB 3QIZA 2G7NA 4EL4A 1G9BA 3QIXA 3DDBA 1Z7HA 1ZN3A 3QW5A 4ZKTB 2W2DA 1F82A 2G7QA 1S0EA 1F31A 3C8BA 2FPQA 1YVGA 3BOKA 3C89A 2A8AA 1S0CA 3FIIA 3V0AB 1E1HA 2G7KA 3ZUQA 2ILPA 1ZKWA 3NF3A 1ZKXA 3ZUSA 3QW8A 3BOOA 3C8AA 3VUOA 2XHLA 3DDAA 2ISEA 4KTXA 4EJ5A 1S0FA 3DEBA 3V0BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BWI A;  3DS9 A;  2ETF A;  2NYY A;  1S0B A;  1ZB7 A;  3C88 A;  1T3A A;  1ZL6 A;  4ZJX A;  2ISG A;  4KS6 A;  4J1L A;  2ISH A;  3K3Q B;  1T3C A;  3DSE A;  3QIY A;  1XTF A;  2IMA A;  3D3X A;  1EPW A;  1G9A A;  3QW6 A;  1G9D A;  5BQN A;  3ZUR A;  3V0A A;  3FIE A;  1S0D A;  3FFZ A;  4KUF A;  3BTA A;  3QJ0 A;  1XTG A;  4HEV A;  1S0G A;  2G7P A;  3QW7 A;  2IMC A;  2QN0 A;  1G9C A;  3BON A;  2NP0 A;  2A97 A;  2IMB A;  5BQM A;  4ELC A;  1I1E A;  1ZL5 A;  2NZ9 A;  3V0B B;  3QIZ A;  2G7N A;  4EL4 A;  1G9B A;  3QIX A;  3DDB A;  1Z7H A;  1ZN3 A;  3QW5 A;  4ZKT B;  2W2D A;  1F82 A;  2G7Q A;  1S0E A;  1F31 A;  3C8B A;  2FPQ A;  1YVG A;  3BOK A;  3C89 A;  2A8A A;  1S0C A;  3FII A;  3V0A B;  1E1H A;  2G7K A;  3ZUQ A;  2ILP A;  1ZKW A;  3NF3 A;  1ZKX A;  3ZUS A;  3QW8 A;  3BOO A;  3C8A A;  3VUO A;  2XHL A;  3DDA A;  2ISE A;  4KTX A;  4EJ5 A;  1S0F A;  3DEB A;  3V0B A; 
#chains in the Genus database with same CATH topology
 3BWI A;  3DS9 A;  2ETF A;  2NYY A;  1S0B A;  1ZB7 A;  3C88 A;  2EJQ A;  1T3A A;  1ZL6 A;  4ZJX A;  2ISG A;  4KS6 A;  4J1L A;  2ISH A;  3K3Q B;  1T3C A;  3DSE A;  3QIY A;  1XTF A;  2IMA A;  3D3X A;  1EPW A;  1G9A A;  3QW6 A;  1G9D A;  5BQN A;  3ZUR A;  3V0A A;  3FIE A;  1S0D A;  3FFZ A;  4KUF A;  3BTA A;  3QJ0 A;  1XTG A;  4HEV A;  3E11 A;  2YPT A;  1S0G A;  2G7P A;  4AW6 A;  3QW7 A;  2IMC A;  2QN0 A;  1G9C A;  3BON A;  2NP0 A;  2A97 A;  2IMB A;  5BQM A;  4ELC A;  4IL3 A;  1I1E A;  1ZL5 A;  2NZ9 A;  4QHF A;  3V0B B;  3QIZ A;  4KTX A;  4EL4 A;  1G9B A;  3QIX A;  3DDB A;  1Z7H A;  4JIU A;  1ZN3 A;  3QW5 A;  4ZKT B;  2W2D A;  1F82 A;  2G7Q A;  4JIX A;  1S0E A;  1F31 A;  3C8B A;  2FPQ A;  1YVG A;  3BOK A;  3C89 A;  2A8A A;  1S0C A;  3FII A;  3V0A B;  1E1H A;  2G7K A;  3ZUQ A;  2ILP A;  1ZKW A;  3NF3 A;  1ZKX A;  3ZUS A;  3CQB A;  3QW8 A;  3BOO A;  3C8A A;  3VUO A;  2XHL A;  3DDA A;  2ISE A;  2G7N A;  4EJ5 A;  1S0F A;  3DEB A;  3V0B A; 
#chains in the Genus database with same CATH homology
 3BWI A;  3DS9 A;  2ETF A;  2NYY A;  1S0B A;  1ZB7 A;  3C88 A;  1T3A A;  1ZL6 A;  4ZJX A;  2ISG A;  4KS6 A;  4J1L A;  2ISH A;  3K3Q B;  1T3C A;  3DSE A;  3QIY A;  1XTF A;  2IMA A;  3D3X A;  1EPW A;  1G9A A;  3QW6 A;  1G9D A;  5BQN A;  3ZUR A;  3V0A A;  3FIE A;  1S0D A;  3FFZ A;  4KUF A;  3BTA A;  3QJ0 A;  1XTG A;  4HEV A;  1S0G A;  2G7P A;  3QW7 A;  2IMC A;  2QN0 A;  1G9C A;  3BON A;  2NP0 A;  2A97 A;  2IMB A;  5BQM A;  4ELC A;  1I1E A;  1ZL5 A;  2NZ9 A;  3V0B B;  3QIZ A;  2G7N A;  4EL4 A;  1G9B A;  3QIX A;  3DDB A;  1Z7H A;  1ZN3 A;  3QW5 A;  4ZKT B;  2W2D A;  1F82 A;  2G7Q A;  1S0E A;  1F31 A;  3C8B A;  2FPQ A;  1YVG A;  3BOK A;  3C89 A;  2A8A A;  1S0C A;  3FII A;  3V0A B;  1E1H A;  2G7K A;  3ZUQ A;  2ILP A;  1ZKW A;  3NF3 A;  1ZKX A;  3ZUS A;  3QW8 A;  3BOO A;  3C8A A;  3VUO A;  2XHL A;  3DDA A;  2ISE A;  4KTX A;  4EJ5 A;  1S0F A;  3DEB A;  3V0B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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