2EZBA

Amino terminal domain of enzyme i from escherichia coli, nmr, 14 structures
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
249
structure length
249
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords PHOSPHOTRANSFERASE SYSTEM, ENZYME I
publication title Defining long range order in NMR structure determination from the dependence of heteronuclear relaxation times on rotational diffusion anisotropy.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Phosphotransferase
total genus 75
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1997-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 2ezbA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 2ezbA01
2FM4A 1VBHA 2X0SA 2MP0A 1KBLA 2HROA 2EZCA 2R82A 1VBGA 3T05A 2EZBA 3EZEA 2DIKA 2E28A 1EZBA 1GGOA 1KC7A 2EZAA 2HWGA 1ZYMA 3EZBA 3EZAA 3T0TA 2OLSA 1EZAA 3T07A 1JDEA 2HI6A 1DIKA 5JVLA
chains in the Genus database with same CATH superfamily
5F9MA 2MX9A 2X0SA 1VBGA 4JYWA 1CX8A 4C9EA 4JZ0A 4MJXA 4C8UA 1KC7A 2A69D 2K3QA 1NBWA 4MCRA 3GTPA 1ZRSA 5F5XA 2LTHA 4OC1A 4COBA 1DIKA 3GTKA 2JA6A 2FM4A 3BI0A 1R61A 1W27A 4C9UA 4NGNA 4P44A 3ICUA 1TWFA 1YNND 1WCMA 4V2RA 4MCQA 2LKMB 3BI1A 3GTMA 3S9MA 3GTQA 3RBUA 3SJEA 4COGA 4C8CA 2E28A 2NVYA 2C5QA 1I3QA 1K83A 4KNGE 3D7DA 4CDKA 4FBSA 2JA5A 3SJXA 2JA7A 1Y9ZA 4NGTA 4NGRA 1J3LA 1ZYRD 3TLYA 3BXMA 1SFOA 4MCSA 4C8AA 2C6CA 3KASA 5F09A 2N1DB 4M8DA 3D7FA 3FKIA 1JDBC 2O5JD 3I6SA 2C6GA 4OC4A 1I6VD 1EZAA 3T07A 2HI6A 2VUMA 2C6PA 2EZCA 1TWAA 3EZEA 2X0PA 4C8FA 3IWWA 2HWGA 3U44A 2YU9A 3EZAA 2OLSA 1CS0B 4P4FA 3T5MA 4C2MA 3G23A 2NVXA 3TLCA 1ZL0A 1SMYD 4IIXA 4NGMA 3TLAA 3U1BA 2JBKA 3EIFA 4P4DA 3D7GA 3S9NA 3CQZA 4CEJA 4TJVA 4C9RA 1VI4A 1Y1VA 4C84A 1T36B 3TLEA 4OC5A 3U4QA 5K99A 2LPJA 5F1YA 3IIBA 1C30B 4INJA 3TYXA 2MP0A 3K9TA 4OC3A 2PVVA 4YN3A 4C6GA 4OC2A 1R9TA 4IIYA 2OOTA 3FECA 1C3OB 1Q5XA 1Z8LA 3TLGA 2CIJA 1CE8B 4W9YA 2YJVA 5JVLA 4P4IA 1KBLA 5FD8A 2LYIA 1EZBA 1M6VB 4OMEA 3VTAA 3I74A 2JBJA 2A6HD 2F5JA 4QIWA 1KEEB 4C9VA 4V2QA 1VBHA 5IB9A 1YNJD 2BE5D 2FIPA 4NGSA 4P4EA 2EZAA 1DE4C 2R7ZA 2XEJA 4CEHA 1TWGA 3TLBA 2MX8A 4P4JA 2PCNA 4OC0A 4H1HA 2X0QA 4C99A 2AUNA 3GTLA 2X0OA 2B0AA 4BABA 1HQMD 2DIKA 3D7HA 2N3EA 2EK9A 3GJZA 1TWCA 2Y0NA 3GTJA 1Y2MA 4E5SA 2AQLA 2AUMA 4C86A 2LPIA 3LR2A 5D29A 3GTOA 2FIOA 5IZ2A 3T05A 2A68D 2EZBA 1NXJA 4P45A 1BXRB 4CZ1A 2A6ED 4C8PA 4CEIA 4NGQA 2K3OA 1T6JA 2D0OA 4C85A 3BHXA 1T6PA 4P4BA 1I50A 2CW0D 4C5UA 2R82A 1IW7D 2MQAA 3KRVA 3NZ4A 4C5SA 2VK9A 2GP4A 2YJTA 3TLGB 4CO9A 2PVWA 3C8OA 4EYSA 4LQGA 2D0PA 3GTGA 1JDEA 1A9XB 1WVMA 2K3NA 2B63A 4CQ5A 3LR8A 4X3RA 4E94A 1TWHA 4MI1A 2XEGA 4MCPA 3S9LA 2E2IA 3SR3A 2EK8A 3T0TA 5IR2A 2YIIA 5JYBA 4NGPA 3LR6A 1Y1WA 3SJGA 2HROA 1XF1A 4BAAA 4C5RA 3FEEA 5ELYA 3H0GA 1V6CA 4CDJA 3NOJA 4J0NA 3TLZA 3SJFA 4C9AA 4C8TA 3FEDA 2OR4A 3K4IA 2E2HA 2XEFA 1GGOA 4TWEA 2XEIA 1ZYMA 3EZBA 3LRDA 2R93A 2R92A 4TJXA 3FF3A 4JVOA
chains in the Genus database with same CATH topology
2FM4A 1VBHA 2X0SA 2MP0A 1KBLA 2HROA 2EZCA 2R82A 1VBGA 3T05A 2EZBA 3EZEA 2DIKA 2E28A 1EZBA 1GGOA 1KC7A 2EZAA 2HWGA 1ZYMA 3EZBA 3EZAA 3T0TA 2OLSA 1EZAA 3T07A 1JDEA 2HI6A 1DIKA 5JVLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FM4 A;  1VBH A;  2X0S A;  2MP0 A;  1KBL A;  2HRO A;  2EZC A;  2R82 A;  1VBG A;  3T05 A;  2EZB A;  3EZE A;  2DIK A;  2E28 A;  1EZB A;  1GGO A;  1KC7 A;  2EZA A;  2HWG A;  1ZYM A;  3EZB A;  3EZA A;  3T0T A;  2OLS A;  1EZA A;  3T07 A;  1JDE A;  2HI6 A;  1DIK A;  5JVL A; 
#chains in the Genus database with same CATH topology
 5F9M A;  2MX9 A;  2X0S A;  1VBG A;  4JYW A;  1CX8 A;  4C9E A;  4JZ0 A;  4MJX A;  4C8U A;  1KC7 A;  2A69 D;  2K3Q A;  1NBW A;  4MCR A;  3GTP A;  1ZRS A;  5F5X A;  2LTH A;  4OC1 A;  4COB A;  1DIK A;  3GTK A;  2JA6 A;  2FM4 A;  3BI0 A;  1R61 A;  1W27 A;  4C9U A;  4NGN A;  4P44 A;  3ICU A;  1TWF A;  1YNN D;  1WCM A;  4V2R A;  4MCQ A;  2LKM B;  3BI1 A;  3GTM A;  3S9M A;  3GTQ A;  3RBU A;  3SJE A;  4COG A;  4C8C A;  2E28 A;  2NVY A;  2C5Q A;  1I3Q A;  1K83 A;  4KNG E;  3D7D A;  4CDK A;  4FBS A;  2JA5 A;  3SJX A;  2JA7 A;  1Y9Z A;  4NGT A;  4NGR A;  1J3L A;  1ZYR D;  3TLY A;  3BXM A;  1SFO A;  4MCS A;  4C8A A;  2C6C A;  3KAS A;  5F09 A;  2N1D B;  4M8D A;  3D7F A;  3FKI A;  1JDB C;  2O5J D;  3I6S A;  2C6G A;  4OC4 A;  1I6V D;  1EZA A;  3T07 A;  2HI6 A;  2VUM A;  2C6P A;  2EZC A;  1TWA A;  3EZE A;  2X0P A;  4C8F A;  3IWW A;  2HWG A;  3U44 A;  2YU9 A;  3EZA A;  2OLS A;  1CS0 B;  4P4F A;  3T5M A;  4C2M A;  3G23 A;  2NVX A;  3TLC A;  1ZL0 A;  1SMY D;  4IIX A;  4NGM A;  3TLA A;  3U1B A;  2JBK A;  3EIF A;  4P4D A;  3D7G A;  3S9N A;  3CQZ A;  4CEJ A;  4TJV A;  4C9R A;  1VI4 A;  1Y1V A;  4C84 A;  1T36 B;  3TLE A;  4OC5 A;  3U4Q A;  5K99 A;  2LPJ A;  5F1Y A;  3IIB A;  1C30 B;  4INJ A;  3TYX A;  2MP0 A;  3K9T A;  4OC3 A;  2PVV A;  4YN3 A;  4C6G A;  4OC2 A;  1R9T A;  4IIY A;  2OOT A;  3FEC A;  1C3O B;  1Q5X A;  1Z8L A;  3TLG A;  2CIJ A;  1CE8 B;  4W9Y A;  2YJV A;  5JVL A;  4P4I A;  1KBL A;  5FD8 A;  2LYI A;  1EZB A;  1M6V B;  4OME A;  3VTA A;  3I74 A;  2JBJ A;  2A6H D;  2F5J A;  4QIW A;  1KEE B;  4C9V A;  4V2Q A;  1VBH A;  5IB9 A;  1YNJ D;  2BE5 D;  2FIP A;  4NGS A;  4P4E A;  2EZA A;  1DE4 C;  2R7Z A;  2XEJ A;  4CEH A;  1TWG A;  3TLB A;  2MX8 A;  4P4J A;  2PCN A;  4OC0 A;  4H1H A;  2X0Q A;  4C99 A;  2AUN A;  3GTL A;  2X0O A;  2B0A A;  4BAB A;  1HQM D;  2DIK A;  3D7H A;  2N3E A;  2EK9 A;  3GJZ A;  1TWC A;  2Y0N A;  3GTJ A;  1Y2M A;  4E5S A;  2AQL A;  2AUM A;  4C86 A;  2LPI A;  3LR2 A;  5D29 A;  3GTO A;  2FIO A;  5IZ2 A;  3T05 A;  2A68 D;  2EZB A;  1NXJ A;  4P45 A;  1BXR B;  4CZ1 A;  2A6E D;  4C8P A;  4CEI A;  4NGQ A;  2K3O A;  1T6J A;  2D0O A;  4C85 A;  3BHX A;  1T6P A;  4P4B A;  1I50 A;  2CW0 D;  4C5U A;  2R82 A;  1IW7 D;  2MQA A;  3KRV A;  3NZ4 A;  4C5S A;  2VK9 A;  2GP4 A;  2YJT A;  3TLG B;  4CO9 A;  2PVW A;  3C8O A;  4EYS A;  4LQG A;  2D0P A;  3GTG A;  1JDE A;  1A9X B;  1WVM A;  2K3N A;  2B63 A;  4CQ5 A;  3LR8 A;  4X3R A;  4E94 A;  1TWH A;  4MI1 A;  2XEG A;  4MCP A;  3S9L A;  2E2I A;  3SR3 A;  2EK8 A;  3T0T A;  5IR2 A;  2YII A;  5JYB A;  4NGP A;  3LR6 A;  1Y1W A;  3SJG A;  2HRO A;  1XF1 A;  4BAA A;  4C5R A;  3FEE A;  5ELY A;  3H0G A;  1V6C A;  4CDJ A;  3NOJ A;  4J0N A;  3TLZ A;  3SJF A;  4C9A A;  4C8T A;  3FED A;  2OR4 A;  3K4I A;  2E2H A;  2XEF A;  1GGO A;  4TWE A;  2XEI A;  1ZYM A;  3EZB A;  3LRD A;  2R93 A;  2R92 A;  4TJX A;  3FF3 A;  4JVO A; 
#chains in the Genus database with same CATH homology
 2FM4 A;  1VBH A;  2X0S A;  2MP0 A;  1KBL A;  2HRO A;  2EZC A;  2R82 A;  1VBG A;  3T05 A;  2EZB A;  3EZE A;  2DIK A;  2E28 A;  1EZB A;  1GGO A;  1KC7 A;  2EZA A;  2HWG A;  1ZYM A;  3EZB A;  3EZA A;  3T0T A;  2OLS A;  1EZA A;  3T07 A;  1JDE A;  2HI6 A;  1DIK A;  5JVL A; 
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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