2EZBA

Amino terminal domain of enzyme i from escherichia coli, nmr, 14 structures
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
249
structure length
249
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Defining long range order in NMR structure determination from the dependence of heteronuclear relaxation times on rotational diffusion anisotropy.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Phosphotransferase
molecule keywords PHOSPHOTRANSFERASE SYSTEM, ENZYME I
total genus 75
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1997-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 2ezbA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 2ezbA01
1EZBA 1JDEA 2HI6A 2R82A 5JVLA 2EZCA 3EZAA 3T07A 2X0SA 2MP0A 1VBHA 2EZBA 2HWGA 1GGOA 2E28A 2DIKA 1KBLA 1ZYMA 1VBGA 3T0TA 2FM4A 3T05A 1EZAA 2EZAA 1KC7A 3EZEA 1DIKA 2OLSA 3EZBA 2HROA
chains in the Genus database with same CATH superfamily
4H1HA 4OC0A 4C5UA 1JDEA 1ZRSA 4TJXA 3CQZA 1VI4A 1WVMA 4V2RA 4QIWA 4OC2A 3NZ4A 5IZ2A 2K3QA 1I3QA 2C6PA 1J3LA 4P44A 2FIPA 2O5JD 1CS0B 3T07A 4JVOA 4E5SA 2R7ZA 1T36B 2GP4A 3BI0A 4NGNA 2HWGA 3BHXA 3FECA 4V2QA 2OLSA 2DIKA 1ZYRD 3TLEA 2CW0D 1YNND 1IW7D 2CIJA 2OR4A 4C8UA 3EIFA 2A6HD 2VUMA 1NBWA 2FM4A 2E2IA 3KRVA 4C5RA 4JZ0A 4P4JA 1C3OB 2YU9A 1TWFA 2NVYA 4OMEA 2BE5D 3GTGA 4OC5A 1TWHA 2B0AA 3SJFA 3IWWA 2FIOA 2JBJA 3K4IA 1I6VD 1Y1VA 2JA5A 4NGPA 1CX8A 4IIXA 2HROA 1T6PA 1EZBA 1C30B 4OC1A 2OOTA 3RBUA 4TWEA 3FF3A 4CEHA 3TYXA 3FEDA 3LRDA 4MCRA 4EYSA 4C5SA 1Q5XA 4J0NA 4M8DA 4C8PA 1YNJD 2C5QA 2EZBA 2PCNA 4MCPA 4C8AA 3S9NA 3GTKA 1TWCA 2E2HA 1Y9ZA 3GJZA 2X0QA 4BAAA 3T5MA 3KASA 4CDKA 2K3NA 3S9LA 1KBLA 1NXJA 4P4IA 2PVWA 2LTHA 1Z8LA 2JA7A 2XEFA 3D7DA 4P4FA 2X0OA 2Y0NA 3FKIA 4COGA 3D7GA 1I50A 3TLGB 3VTAA 3TLBA 4MI1A 4BABA 2X0PA 3I6SA 4NGRA 3GTOA 2JA6A 2A6ED 2PVVA 5F1YA 3TLGA 4C9EA 3GTPA 2AUNA 3EZBA 2MQAA 2LKMB 3LR2A 3BXMA 2K3OA 2XEJA 3BI1A 5JVLA 2R92A 4OC3A 2C6GA 3TLAA 2AUMA 2VK9A 1XF1A 2JBKA 3EZAA 1M6VB 5F9MA 4W9YA 3GTLA 4NGSA 4C8FA 4CDJA 4MCQA 2MP0A 3TLZA 4OC4A 4C9VA 4COBA 4C9UA 4C9RA 1JDBC 4MCSA 4CQ5A 3FEEA 3LR6A 3TLCA 5K99A 2EK9A 4LQGA 4NGTA 5F5XA 3C8OA 3SJXA 1VBGA 3T0TA 4C85A 4NGQA 3K9TA 3SJGA 1EZAA 2EZAA 4C6GA 1Y1WA 4C2MA 1DIKA 5FD8A 1ZL0A 5IR2A 4C8TA 3U1BA 4NGMA 4P4BA 1R9TA 2YIIA 4CEIA 4CO9A 2B63A 2HI6A 3NOJA 2MX8A 2R82A 2D0OA 1A9XB 1W27A 2EZCA 2LYIA 2AQLA 4INJA 1BXRB 2XEGA 3I74A 4C84A 3G23A 2EK8A 3U4QA 2F5JA 1TWGA 1V6CA 1R61A 2XEIA 2YJTA 3IIBA 2X0SA 3D7FA 4P4EA 4X3RA 1Y2MA 3GTMA 2N1DB 1VBHA 4KNGE 1SMYD 4P45A 5ELYA 4C9AA 3U44A 4C86A 3S9MA 4YN3A 3SR3A 1GGOA 2E28A 2N3EA 4IIYA 5F09A 4P4DA 4CZ1A 1HQMD 1K83A 3GTQA 2C6CA 3GTJA 2D0PA 3D7HA 1T6JA 2A68D 2NVXA 2YJVA 1ZYMA 5JYBA 4CEJA 1CE8B 3LR8A 4C99A 1DE4C 4MJXA 3SJEA 2LPIA 3T05A 1KEEB 4E94A 1SFOA 3TLYA 1KC7A 4JYWA 3EZEA 2R93A 1TWAA 4TJVA 5D29A 5IB9A 2LPJA 4C8CA 2MX9A 1WCMA 3H0GA 4FBSA 2A69D 3ICUA
chains in the Genus database with same CATH topology
1EZBA 1JDEA 2HI6A 2R82A 5JVLA 2EZCA 3EZAA 3T07A 2X0SA 2MP0A 1VBHA 2EZBA 2HWGA 1GGOA 2E28A 2DIKA 1KBLA 1ZYMA 1VBGA 3T0TA 2FM4A 3T05A 1EZAA 2EZAA 1KC7A 3EZEA 1DIKA 2OLSA 3EZBA 2HROA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EZB A;  1JDE A;  2HI6 A;  2R82 A;  5JVL A;  2EZC A;  3EZA A;  3T07 A;  2X0S A;  2MP0 A;  1VBH A;  2EZB A;  2HWG A;  1GGO A;  2E28 A;  2DIK A;  1KBL A;  1ZYM A;  1VBG A;  3T0T A;  2FM4 A;  3T05 A;  1EZA A;  2EZA A;  1KC7 A;  3EZE A;  1DIK A;  2OLS A;  3EZB A;  2HRO A; 
#chains in the Genus database with same CATH topology
 4H1H A;  4OC0 A;  4C5U A;  1JDE A;  1ZRS A;  4TJX A;  3CQZ A;  1VI4 A;  1WVM A;  4V2R A;  4QIW A;  4OC2 A;  3NZ4 A;  5IZ2 A;  2K3Q A;  1I3Q A;  2C6P A;  1J3L A;  4P44 A;  2FIP A;  2O5J D;  1CS0 B;  3T07 A;  4JVO A;  4E5S A;  2R7Z A;  1T36 B;  2GP4 A;  3BI0 A;  4NGN A;  2HWG A;  3BHX A;  3FEC A;  4V2Q A;  2OLS A;  2DIK A;  1ZYR D;  3TLE A;  2CW0 D;  1YNN D;  1IW7 D;  2CIJ A;  2OR4 A;  4C8U A;  3EIF A;  2A6H D;  2VUM A;  1NBW A;  2FM4 A;  2E2I A;  3KRV A;  4C5R A;  4JZ0 A;  4P4J A;  1C3O B;  2YU9 A;  1TWF A;  2NVY A;  4OME A;  2BE5 D;  3GTG A;  4OC5 A;  1TWH A;  2B0A A;  3SJF A;  3IWW A;  2FIO A;  2JBJ A;  3K4I A;  1I6V D;  1Y1V A;  2JA5 A;  4NGP A;  1CX8 A;  4IIX A;  2HRO A;  1T6P A;  1EZB A;  1C30 B;  4OC1 A;  2OOT A;  3RBU A;  4TWE A;  3FF3 A;  4CEH A;  3TYX A;  3FED A;  3LRD A;  4MCR A;  4EYS A;  4C5S A;  1Q5X A;  4J0N A;  4M8D A;  4C8P A;  1YNJ D;  2C5Q A;  2EZB A;  2PCN A;  4MCP A;  4C8A A;  3S9N A;  3GTK A;  1TWC A;  2E2H A;  1Y9Z A;  3GJZ A;  2X0Q A;  4BAA A;  3T5M A;  3KAS A;  4CDK A;  2K3N A;  3S9L A;  1KBL A;  1NXJ A;  4P4I A;  2PVW A;  2LTH A;  1Z8L A;  2JA7 A;  2XEF A;  3D7D A;  4P4F A;  2X0O A;  2Y0N A;  3FKI A;  4COG A;  3D7G A;  1I50 A;  3TLG B;  3VTA A;  3TLB A;  4MI1 A;  4BAB A;  2X0P A;  3I6S A;  4NGR A;  3GTO A;  2JA6 A;  2A6E D;  2PVV A;  5F1Y A;  3TLG A;  4C9E A;  3GTP A;  2AUN A;  3EZB A;  2MQA A;  2LKM B;  3LR2 A;  3BXM A;  2K3O A;  2XEJ A;  3BI1 A;  5JVL A;  2R92 A;  4OC3 A;  2C6G A;  3TLA A;  2AUM A;  2VK9 A;  1XF1 A;  2JBK A;  3EZA A;  1M6V B;  5F9M A;  4W9Y A;  3GTL A;  4NGS A;  4C8F A;  4CDJ A;  4MCQ A;  2MP0 A;  3TLZ A;  4OC4 A;  4C9V A;  4COB A;  4C9U A;  4C9R A;  1JDB C;  4MCS A;  4CQ5 A;  3FEE A;  3LR6 A;  3TLC A;  5K99 A;  2EK9 A;  4LQG A;  4NGT A;  5F5X A;  3C8O A;  3SJX A;  1VBG A;  3T0T A;  4C85 A;  4NGQ A;  3K9T A;  3SJG A;  1EZA A;  2EZA A;  4C6G A;  1Y1W A;  4C2M A;  1DIK A;  5FD8 A;  1ZL0 A;  5IR2 A;  4C8T A;  3U1B A;  4NGM A;  4P4B A;  1R9T A;  2YII A;  4CEI A;  4CO9 A;  2B63 A;  2HI6 A;  3NOJ A;  2MX8 A;  2R82 A;  2D0O A;  1A9X B;  1W27 A;  2EZC A;  2LYI A;  2AQL A;  4INJ A;  1BXR B;  2XEG A;  3I74 A;  4C84 A;  3G23 A;  2EK8 A;  3U4Q A;  2F5J A;  1TWG A;  1V6C A;  1R61 A;  2XEI A;  2YJT A;  3IIB A;  2X0S A;  3D7F A;  4P4E A;  4X3R A;  1Y2M A;  3GTM A;  2N1D B;  1VBH A;  4KNG E;  1SMY D;  4P45 A;  5ELY A;  4C9A A;  3U44 A;  4C86 A;  3S9M A;  4YN3 A;  3SR3 A;  1GGO A;  2E28 A;  2N3E A;  4IIY A;  5F09 A;  4P4D A;  4CZ1 A;  1HQM D;  1K83 A;  3GTQ A;  2C6C A;  3GTJ A;  2D0P A;  3D7H A;  1T6J A;  2A68 D;  2NVX A;  2YJV A;  1ZYM A;  5JYB A;  4CEJ A;  1CE8 B;  3LR8 A;  4C99 A;  1DE4 C;  4MJX A;  3SJE A;  2LPI A;  3T05 A;  1KEE B;  4E94 A;  1SFO A;  3TLY A;  1KC7 A;  4JYW A;  3EZE A;  2R93 A;  1TWA A;  4TJV A;  5D29 A;  5IB9 A;  2LPJ A;  4C8C A;  2MX9 A;  1WCM A;  3H0G A;  4FBS A;  2A69 D;  3ICU A; 
#chains in the Genus database with same CATH homology
 1EZB A;  1JDE A;  2HI6 A;  2R82 A;  5JVL A;  2EZC A;  3EZA A;  3T07 A;  2X0S A;  2MP0 A;  1VBH A;  2EZB A;  2HWG A;  1GGO A;  2E28 A;  2DIK A;  1KBL A;  1ZYM A;  1VBG A;  3T0T A;  2FM4 A;  3T05 A;  1EZA A;  2EZA A;  1KC7 A;  3EZE A;  1DIK A;  2OLS A;  3EZB A;  2HRO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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