2EZWA

Solution structure of the docking and dimerization domain of the type i alpha regulatory subunit of protein kinase a (rialpha d/d)
Total Genus 10
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
50
structure length
50
Chain Sequence
SLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFEKLEKEEAK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transferase
molecule keywords cAMP-dependent protein kinase type I-alpha regulatory subuni
publication title Related Protein-Protein Interaction Modules Present Drastically Different Surface Topographies Despite A Conserved Helical Platform
pubmed doi rcsb
source organism Bos taurus
total genus 10
structure length 50
sequence length 50
chains with identical sequence B
ec nomenclature ec 2.7.1.37: Transferred entry: 2.7.11.1, 2.7.11.8, 2.7.11.9, 2.7.11.10, 2.7.11.11,
pdb deposition date 2005-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02197 RIIa Regulatory subunit of type II PKA R-subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 2ezwA00
1L6EA 3IM4A 2H9RA 4ZP3A 5HVZA 4F9KA 2KYGA 3G36A 3IM3A 4RTAA 4RT4A 1R2AA 2DRNA 2EZWA 2IZYA 4RIQA
chains in the Genus database with same CATH superfamily
2RQYA 3QG0A 3S4CA 4ZP3A 3RSYA 3RRSA 3G36A 2CQTA 2CB9A 3S4AA 4F9KA 2CQSA 3S4BA 2KYGA 3ACSA 2K9QA 2KNGA 3GWHA 3ACTA 3AFJA 4RTAA 1R2AA 2DRNA 3IM3A 3PMIA 3QFYA 4RIQA 1L6EA 3IM4A 2H9RA 2I15A 5HVZA 3UFEA 3QFZA 2OUTA 3QDEA 3S4DA 4RT4A 2IZYA 2EZWA 2CBGA
chains in the Genus database with same CATH topology
1L6EA 3IM4A 2H9RA 4ZP3A 5HVZA 4F9KA 2KYGA 3G36A 3IM3A 4RTAA 4RT4A 1R2AA 2DRNA 2EZWA 2IZYA 4RIQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1L6E A;  3IM4 A;  2H9R A;  4ZP3 A;  5HVZ A;  4F9K A;  2KYG A;  3G36 A;  3IM3 A;  4RTA A;  4RT4 A;  1R2A A;  2DRN A;  2EZW A;  2IZY A;  4RIQ A; 
#chains in the Genus database with same CATH topology
 2RQY A;  3QG0 A;  3S4C A;  4ZP3 A;  3RSY A;  3RRS A;  3G36 A;  2CQT A;  2CB9 A;  3S4A A;  4F9K A;  2CQS A;  3S4B A;  2KYG A;  3ACS A;  2K9Q A;  2KNG A;  3GWH A;  3ACT A;  3AFJ A;  4RTA A;  1R2A A;  2DRN A;  3IM3 A;  3PMI A;  3QFY A;  4RIQ A;  1L6E A;  3IM4 A;  2H9R A;  2I15 A;  5HVZ A;  3UFE A;  3QFZ A;  2OUT A;  3QDE A;  3S4D A;  4RT4 A;  2IZY A;  2EZW A;  2CBG A; 
#chains in the Genus database with same CATH homology
 1L6E A;  3IM4 A;  2H9R A;  4ZP3 A;  5HVZ A;  4F9K A;  2KYG A;  3G36 A;  3IM3 A;  4RTA A;  4RT4 A;  1R2A A;  2DRN A;  2EZW A;  2IZY A;  4RIQ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...