2F25A

Crystal structure of the human sialidase neu2 e111q mutant in complex with dana inhibitor
Total Genus 101
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
377
structure length
373
Chain Sequence
MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTQQQQLQTRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLNDRARSLVVPAYAYRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVETGEQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSPAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAEY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Human Sialidase Neu2 E111Q Mutant in Complex with DANA Inhibitor
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Sialidase 2
total genus 101
structure length 373
sequence length 377
chains with identical sequence B
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 2005-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13088 BNR_2 BNR repeat-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 2f25A00
4MWUA 4I00A 2HU4A 5JYYA 1V0EA 2VK6A 4GZWA 3BEQA 1IVCA 2YA7A 1W0PA 4YZ2A 1W8NA 3CKZA 4WEFA 1IVDA 2QWDA 4M4VA 4CPLA 3H6JA 1XOGA 2XZKA 4X6KA 2YA5A 1E8UA 4J9TA 4YW4A 3ALWA 2SLIA 4NN9A 3CL0A 1E8TA 4CPZA 1N1YA 1NCCN 1N1TA 1NSDA 3B69A 4XJ9A 1NNCA 3GVJA 2A75A 3K39A 4B7NA 4D8SA 4XJAA 4GZTA 1A4GA 4M3MA 2F13A 4Q6KA 4QN5A 1MZ6A 4XHXA 1EURA 2VVZA 3NSSA 1IVFA 1SNTA 1V0FA 2QWEA 4FJ6A 4MWYA 1VCUA 3CL2A 3D11A 2VK5A 4KS4A 4H53A 1MS3A 4MWWA 1IVBA 3H73A 4B7MA 4XYXA 1WCQA 1Z50A 1USRA 1Z4VA 4HZVA 5HUNA 2W5OA 1MR5A 1B9SA 1INXA 5NN9A 4K1HA 4FPHA 2YDPA 1NN2A 2AEPA 2B8HA 1NSCA 1L7GA 1W0OA 2ZB6A 1Z4WA 4H52A 4XJ8A 1MS8A 2RKCA 3SLIA 4FOYA 4WA4A 4FPFA 4XJRA 2VSMA 2F29A 2QWBA 4X47A 2W5NA 1F8BA 4WA5A 1USXA 2F25A 2QWFA 3OPZA 2F27A 1B9TA 2W38A 4B7RA 4MWLA 2JKBA 4B7QA 2VW1A 2CMLA 2SIMA 1BJIA 5HUMA 2C4AA 4MWRA 1MS9A 2AEQA 3K38A 4FPYA 2VSKA 1NMCA 3TI6A 2HU0A 3H72A 1MS4A 1EUTA 2BATA 2F11A 4FVKA 5HUKA 1NCBN 2AH2A 4KS5A 4XJZA 4BBWA 2VWDA 4YZ1A 1KITA 3SALA 1F8CA 2HTRA 4XILA 1L7FA 2QWIA 4CPYA 4QN6A 3O9JA 4QN4A 1N1SA 1SO7A 1V0ZA 1Z4ZA 4GEZA 4X49A 4JF7A 1A14N 2QWJA 4K1KA 4QN7A 1MWEA 1DIMA 4XJWA 2BF6A 4YZ3A 2F28A 5F9TA 2VK7A 4FPGA 1MZ5A 2QWCA 4MJUA 4FPOB 3K3AA 3B7EA 3TIAA 4YZ4A 1V3BA 4GZPA 2BZDA 1VCJA 3TI3A 2XCYA 5HUGA 4YW1A 1W21A 4GDIA 2AGSA 3TIBA 4XIKA 1MS1A 2SILA 1L7HA 4GZXA 2YDTA 4FPKA 3JU4A 4M4NA 2HTVA 2F12A 4FP2A 4MWXA 3TICA 1Z4XA 4K1IA 2F10A 4HZZA 3CYEA 3TI4A 2HT8A 2VW2A 4HZYA 2QWHA 1E8VA 3GVKA 3INBA 2YA4A 4XJUA 4GB1A 5M1ZA 4FPJA 4SLIA 4XJQA 1INVA 4FOVA 2HT5A 4K3YA 1F8EA 2YA6A 1NNBA 2YA8A 3O9KA 1V3EA 6NN9A 4MJVA 4MWQA 2QWGA 2W20A 4MWJA 4MZEA 1NCDN 2BERA 3W09A 3A72A 4YW2A 4QNPA 1XOEA 4M4UA 4B7JA 2F26A 2HTWA 3GVLA 2HTUA 3T1EA 1S0JA 3ALXA 4CPNA 2HTYA 2X9MA 4YW3A 1NCAN 2XZJA 4MC7A 3H71A 4KS3A 1INWA 5B2CA 1NSBA 4GJTA 5B2DA 4GZQA 1IVGA 4QN3A 4DGRA 1S0IA 1EUSA 4FP3A 2XZIA 4NC5A 4GDJA 1DILA 2F24A 4MZAA 4XIOA 1MS5A 3D12A 4GZSA 1N1VA 1V2IA 4FOQA 2C4LA 3TI8A 1SLLA 3K36A 4FZHA 1A4QA 1NMAN 4XOGA 4CPOA 1MS0A 1EUUA 1V3DA 1WCSA 4XE9A 4UF7A 1IVEA 3SILA 4HZWA 4XMAA 2HTQA 4FPLA 4X4AA 1INGA 4YZ5A 1NNAA 4FPEA 4WA3A 2HT7A 4FPCA 1V3CA 1W1XA 1W8OA 3TI5A 1NMBN 4KS1A 1SLIA 4HZXA 4KS2A 4FQ4A 5HX0A 1INYA 7NN9A 4HIZA 2QWKA 4XHBA 4CPMA 4GZOA 1Z4YA 4NCSA 4FOWA 4MWVA 2VW0A 2FHRA 4MX0A 2F0ZA 2ZB5A 4XMIA 3PJQA 1F8DA 1B9VA 4YW5A 3K37A 3NN9A 3A71A 1INFA 1INHA 4K1JA 3SANA 1W20A 4WEGA 2QWAA
chains in the Genus database with same CATH superfamily
4MWUA 4ZY3A 4L7DA 4I00A 3KGGA 2HU4A 4R40A 5JYYA 1V0EA 2VK6A 5FWWA 4GZWA 3BEQA 2VAQA 1IVCA 5FNTA 2YA7A 1W0PA 4YZ2A 1W8NA 3CKZA 4WEFA 1IVDA 2QWDA 4M4VA 4CPLA 3H6JA 1XOGA 2XZKA 4X6KA 1V04A 2YA5A 1E8UA 3AMRA 4J9TA 4YW4A 2IARA 3ALWA 1QLGA 2SLIA 4NN9A 3CL0A 1E8TA 4CPZA 1N1YA 1NCCN 3IAXA 1N1TA 4A0PA 1NSDA 3B69A 5FZJA 1PJXA 3DASA 4XJ9A 1NNCA 3GVJA 2A75A 3K39A 3VNHA 4B7NA 4D8SA 4XJAA 4GZTA 1A4GA 3ZGCA 3V65B 1QBIA 4M3MA 4UOUA 4IQKA 4AGIA 3WN7A 2F13A 4Q6KA 4QN5A 3WDZA 1MZ6A 4XHXA 1EURA 2VVZA 3NSSA 4HHOA 1IVFA 2OJHA 4L7BA 1SNTA 1V0FA 2QWEA 4FJ6A 4MWYA 1VCUA 3CL2A 3D11A 2VK5A 4KS4A 4H53A 1MS3A 3G4HA 4MWWA 4GNBA 4DG6A 1IVBA 3AMSA 3H73A 4B7MA 4XYXA 1RWIA 2IAUA 1WCQA 1Z50A 1USRA 1N6FA 1Z4VA 4HZVA 5HUNA 2W5OA 1OFZA 1MR5A 1B9SA 3V1SA 1INXA 5NN9A 4K1HA 2FP9A 4FPHA 2YDPA 4D52A 1NN2A 4D4UA 2AEPA 1ZGKA 2B8HA 1NSCA 1L7GA 1W0OA 1H6LA 1Z4WA 2ZB6A 3FVZA 3P5BL 5FNUA 4H52A 1IJQA 4XJ8A 1MS8A 2RKCA 3SLIA 4FOYA 4WA4A 1N6DA 5CGJA 4FPFA 4XJRA 2VSMA 3A9GA 2F29A 2QWBA 4X47A 2W5NA 1F8BA 4IFLX 4WA5A 1USXA 5FNQA 2F25A 2QWFA 2W8BB 3OPZA 2F27A 4G3NA 4L7CA 1B9TA 2W38A 1RWLA 4B7RA 1CQ1A 2Z32A 4MWLA 2JKBA 3LI5A 4B7QA 5FNSA 2VW1A 2CMLA 2SIMA 1BJIA 2V91A 5HUMA 2C4AA 4MWRA 1MS9A 2AEQA 2IAVA 3DR2A 3ZGDA 3L6VA 5D9BA 3NO0A 3K38A 3TC9A 2QE8A 4FPYA 2VSKA 1NMCA 3TI6A 3UC1A 1WP5A 2HU0A 3H72A 1MS4A 1EUTA 2BATA 2F11A 4FVKA 5HUKA 1NCBN 3Q6PA 2AH2A 3ADEA 3G4EA 2FPBA 4KS5A 4XJZA 4BBWA 2ZW9A 2IASA 2VWDA 3FW0A 4YZ1A 4GN8A 1KITA 3SALA 1E1AA 1CRZA 1F8CA 2HTRA 4XILA 2G8SA 1L7FA 2QWIA 3Q6TA 4CPYA 4QN6A 1N7DA 3O9JA 3HRPA 5D9CA 4QN4A 1N1SA 2DG1A 2DSOA 1SO7A 1V0ZA 1Z4ZA 4GEZA 3E5ZA 4X49A 4JF7A 1A14N 2QWJA 3WW9A 4K1KA 4QN7A 1MWEA 1DIMA 4XJWA 2BF6A 4YZ3A 2W8BA 1X2RA 3Q6KA 2F28A 5F9TA 4GNCA 2VK7A 4FPGA 1MZ5A 2QWCA 4MJUA 4FPOB 1IUCA 3K3AA 3B7EA 3TIAA 4YZ4A 2IAPA 1V3BA 2IAOA 4C1YB 4GZPA 2BZDA 3A9HA 5FNRA 5GX2A 1VCJA 4GN7A 4IFNX 3TI3A 2HQSA 2XCYA 4IYGA 5HUGA 4YW1A 2ZZKA 3U0SA 1W21A 3VNGA 4GDIA 2AGSA 5EO7A 2ISMA 3TIBA 1CVMA 4XIKA 1MS1A 2SILA 4CH9A 1L7HA 4GZXA 5F72C 5EO8A 2YDTA 4FPKA 1S18A 4GN9A 3JU4A 4ZGCA 4M4NA 2HTVA 2F12A 2GVWA 3WWAA 4FP2A 4AGTA 4MWXA 2H2NA 2GVVA 4O5SA 3TICA 1Z4XA 4N1BA 4K1IA 2DYHA 2F10A 4D52C 3V64C 4HZZA 2GVXA 2FLUX 3CYEA 3TI4A 2HT8A 2VW2A 4HZYA 2QWHA 2IVZA 1E8VA 2GVUA 3GVKA 3INBA 4ASCA 3I1CA 4IMBA 2FPCA 3SOBB 2YA4A 4XJUA 4GB1A 5M1ZA 3SOQA 4FPJA 2DG0A 4SLIA 4XJQA 1INVA 4FOVA 2HT5A 3SREA 4K3YA 1F8EA 2YA6A 1NNBA 2YA8A 3O9KA 4ZLRA 1V3EA 6NN9A 5GX1A 4MJVA 4MWQA 2QWGA 2W20A 4MWJA 4MZEA 1NCDN 3S2KA 2BERA 3W09A 3A72A 2XN4A 4YW2A 3II7A 4QNPA 1XOEA 4M4UA 4B7JA 2F26A 5GX3A 2HTWA 3GVLA 2HTUA 1C9UA 3T1EA 4AH4A 1CRUA 1S0JA 4IFJA 3ALXA 5FZNA 4CPNA 2HTYA 2X9MA 4YW3A 1NCAN 5GX5A 2XZJA 3BYCA 4MC7A 3H71A 4KS3A 3LI4A 3KYAA 1INWA 2POOA 5B2CA 1NSBA 3LI3A 4GJTA 3SOVA 4D52B 2IAQA 4CHBA 2IAXA 5B2DA 4GZQA 1IVGA 4QN3A 2IAWA 4DGRA 1S0IA 1EUSA 4FP3A 1Q7FA 2XZIA 4NC5A 4GDJA 1DILA 3SRGA 2IATA 2F24A 4HW6A 4MZAA 4XIOA 1MS5A 3D12A 3S8ZA 1POOA 4GZSA 5GTQA 1N1VA 1V2IA 4FOQA 2C4LA 4Q1UA 3TI8A 1SLLA 3K36A 5GX4A 4FZHA 1A4QA 3HLHA 1NMAN 4XOGA 1SUUA 4IN4A 4O5TA 1C5KA 4CPOA 3O4PA 1MS0A 2ZWAA 1EUUA 1V3DA 1WCSA 4XE9A 4UF7A 1IVEA 3S94A 3SILA 4HZWA 4XMAA 2HTQA 1IUBA 2GHSA 1K32A 4FPLA 4X4AA 1INGA 4YZ5A 2FP8A 1NNAA 4FPEA 1X2JA 2HT7A 2VPJA 4WA3A 4FPCA 1V3CA 1W1XA 1W8OA 4GNAA 1N6EA 3TI5A 2P4OA 1NMBN 3S8VA 4KS1A 1SLIA 1U6DX 4PWZA 4HZXA 4KS2A 4FQ4A 5HX0A 1INYA 7NN9A 4HIZA 2QWKA 4XHBA 4CPMA 1NPEA 4GZOA 1Z4YA 4NCSA 4FOWA 4MWVA 3HLIA 4XMBA 2WOZA 2VW0A 4AHAA 2FHRA 4HHQA 2F0ZA 4MX0A 4JMLA 2ZB5A 4XMIA 5H47A 3PJQA 2H2UA 1F8DA 1B9VA 5EX7A 4C1YA 4YW5A 5D9DA 4YY8A 3K37A 3NN9A 4CSDA 3A71A 1INFA 1S1DA 1INHA 4K1JA 3SANA 1W20A 4WEGA 2QWAA 1ZI0A
chains in the Genus database with same CATH topology
4MWUA 4I00A 2HU4A 5JYYA 1V0EA 2VK6A 4GZWA 3BEQA 1IVCA 2YA7A 1W0PA 4YZ2A 1W8NA 3CKZA 4WEFA 1IVDA 2QWDA 4M4VA 4CPLA 3H6JA 1XOGA 2XZKA 4X6KA 2YA5A 1E8UA 4J9TA 4YW4A 3ALWA 2SLIA 4NN9A 3CL0A 1E8TA 4CPZA 1N1YA 1NCCN 1N1TA 1NSDA 3B69A 4XJ9A 1NNCA 3GVJA 2A75A 3K39A 4B7NA 4D8SA 4XJAA 4GZTA 1A4GA 4M3MA 2F13A 4Q6KA 4QN5A 1MZ6A 4XHXA 1EURA 2VVZA 3NSSA 1IVFA 1SNTA 1V0FA 2QWEA 4FJ6A 4MWYA 1VCUA 3CL2A 3D11A 2VK5A 4KS4A 4H53A 1MS3A 4MWWA 1IVBA 3H73A 4B7MA 4XYXA 1WCQA 1Z50A 1USRA 1Z4VA 4HZVA 5HUNA 2W5OA 1MR5A 1B9SA 1INXA 5NN9A 4K1HA 4FPHA 2YDPA 1NN2A 2AEPA 2B8HA 1NSCA 1L7GA 1W0OA 2ZB6A 1Z4WA 4H52A 4XJ8A 1MS8A 2RKCA 3SLIA 4FOYA 4WA4A 4FPFA 4XJRA 2VSMA 2F29A 2QWBA 4X47A 2W5NA 1F8BA 4WA5A 1USXA 2F25A 2QWFA 3OPZA 2F27A 1B9TA 2W38A 4B7RA 4MWLA 2JKBA 4B7QA 2VW1A 2CMLA 2SIMA 1BJIA 5HUMA 2C4AA 4MWRA 1MS9A 2AEQA 3K38A 4FPYA 2VSKA 1NMCA 3TI6A 2HU0A 3H72A 1MS4A 1EUTA 2BATA 2F11A 4FVKA 5HUKA 1NCBN 2AH2A 4KS5A 4XJZA 4BBWA 2VWDA 4YZ1A 1KITA 3SALA 1F8CA 2HTRA 4XILA 1L7FA 2QWIA 4CPYA 4QN6A 3O9JA 4QN4A 1N1SA 1SO7A 1V0ZA 1Z4ZA 4GEZA 4X49A 4JF7A 1A14N 2QWJA 4K1KA 4QN7A 1MWEA 1DIMA 4XJWA 2BF6A 4YZ3A 2F28A 5F9TA 2VK7A 4FPGA 1MZ5A 2QWCA 4MJUA 4FPOB 3K3AA 3B7EA 3TIAA 4YZ4A 1V3BA 4GZPA 2BZDA 1VCJA 3TI3A 2XCYA 5HUGA 4YW1A 1W21A 4GDIA 2AGSA 3TIBA 4XIKA 1MS1A 2SILA 1L7HA 4GZXA 2YDTA 4FPKA 1S18A 3JU4A 4M4NA 2HTVA 2F12A 4FP2A 4MWXA 2H2NA 3TICA 1Z4XA 4K1IA 2F10A 4HZZA 3CYEA 3TI4A 2HT8A 2VW2A 4HZYA 2QWHA 1E8VA 3GVKA 3INBA 2YA4A 4XJUA 4GB1A 5M1ZA 4FPJA 4SLIA 4XJQA 1INVA 4FOVA 2HT5A 4K3YA 1F8EA 2YA6A 1NNBA 2YA8A 3O9KA 1V3EA 6NN9A 4MJVA 4MWQA 2QWGA 2W20A 4MWJA 4MZEA 1NCDN 2BERA 3W09A 3A72A 4YW2A 4QNPA 1XOEA 4M4UA 4B7JA 2F26A 2HTWA 3GVLA 2HTUA 3T1EA 1S0JA 3ALXA 4CPNA 2HTYA 2X9MA 4YW3A 1NCAN 2XZJA 4MC7A 3H71A 4KS3A 1INWA 5B2CA 1NSBA 4GJTA 5B2DA 4GZQA 1IVGA 4QN3A 4DGRA 1S0IA 1EUSA 4FP3A 2XZIA 4NC5A 4GDJA 1DILA 2F24A 4MZAA 4XIOA 1MS5A 3D12A 4GZSA 1N1VA 1V2IA 4FOQA 2C4LA 3TI8A 1SLLA 3K36A 4FZHA 1A4QA 1NMAN 4XOGA 4CPOA 1MS0A 1EUUA 1V3DA 1WCSA 4XE9A 4UF7A 1IVEA 3SILA 4HZWA 4XMAA 2HTQA 4FPLA 4X4AA 1INGA 4YZ5A 1NNAA 4FPEA 4WA3A 2HT7A 4FPCA 1V3CA 1W1XA 1W8OA 3TI5A 1NMBN 4KS1A 1SLIA 4HZXA 4KS2A 4FQ4A 5HX0A 1INYA 7NN9A 4HIZA 2QWKA 4XHBA 4CPMA 4GZOA 1Z4YA 4NCSA 4FOWA 4MWVA 2VW0A 2FHRA 4MX0A 2F0ZA 2ZB5A 4XMIA 3PJQA 2H2UA 1F8DA 1B9VA 4YW5A 3K37A 3NN9A 3A71A 1INFA 1S1DA 1INHA 4K1JA 3SANA 1W20A 4WEGA 2QWAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MWU A;  4I00 A;  2HU4 A;  5JYY A;  1V0E A;  2VK6 A;  4GZW A;  3BEQ A;  1IVC A;  2YA7 A;  1W0P A;  4YZ2 A;  1W8N A;  3CKZ A;  4WEF A;  1IVD A;  2QWD A;  4M4V A;  4CPL A;  3H6J A;  1XOG A;  2XZK A;  4X6K A;  2YA5 A;  1E8U A;  4J9T A;  4YW4 A;  3ALW A;  2SLI A;  4NN9 A;  3CL0 A;  1E8T A;  4CPZ A;  1N1Y A;  1NCC N;  1N1T A;  1NSD A;  3B69 A;  4XJ9 A;  1NNC A;  3GVJ A;  2A75 A;  3K39 A;  4B7N A;  4D8S A;  4XJA A;  4GZT A;  1A4G A;  4M3M A;  2F13 A;  4Q6K A;  4QN5 A;  1MZ6 A;  4XHX A;  1EUR A;  2VVZ A;  3NSS A;  1IVF A;  1SNT A;  1V0F A;  2QWE A;  4FJ6 A;  4MWY A;  1VCU A;  3CL2 A;  3D11 A;  2VK5 A;  4KS4 A;  4H53 A;  1MS3 A;  4MWW A;  1IVB A;  3H73 A;  4B7M A;  4XYX A;  1WCQ A;  1Z50 A;  1USR A;  1Z4V A;  4HZV A;  5HUN A;  2W5O A;  1MR5 A;  1B9S A;  1INX A;  5NN9 A;  4K1H A;  4FPH A;  2YDP A;  1NN2 A;  2AEP A;  2B8H A;  1NSC A;  1L7G A;  1W0O A;  2ZB6 A;  1Z4W A;  4H52 A;  4XJ8 A;  1MS8 A;  2RKC A;  3SLI A;  4FOY A;  4WA4 A;  4FPF A;  4XJR A;  2VSM A;  2F29 A;  2QWB A;  4X47 A;  2W5N A;  1F8B A;  4WA5 A;  1USX A;  2F25 A;  2QWF A;  3OPZ A;  2F27 A;  1B9T A;  2W38 A;  4B7R A;  4MWL A;  2JKB A;  4B7Q A;  2VW1 A;  2CML A;  2SIM A;  1BJI A;  5HUM A;  2C4A A;  4MWR A;  1MS9 A;  2AEQ A;  3K38 A;  4FPY A;  2VSK A;  1NMC A;  3TI6 A;  2HU0 A;  3H72 A;  1MS4 A;  1EUT A;  2BAT A;  2F11 A;  4FVK A;  5HUK A;  1NCB N;  2AH2 A;  4KS5 A;  4XJZ A;  4BBW A;  2VWD A;  4YZ1 A;  1KIT A;  3SAL A;  1F8C A;  2HTR A;  4XIL A;  1L7F A;  2QWI A;  4CPY A;  4QN6 A;  3O9J A;  4QN4 A;  1N1S A;  1SO7 A;  1V0Z A;  1Z4Z A;  4GEZ A;  4X49 A;  4JF7 A;  1A14 N;  2QWJ A;  4K1K A;  4QN7 A;  1MWE A;  1DIM A;  4XJW A;  2BF6 A;  4YZ3 A;  2F28 A;  5F9T A;  2VK7 A;  4FPG A;  1MZ5 A;  2QWC A;  4MJU A;  4FPO B;  3K3A A;  3B7E A;  3TIA A;  4YZ4 A;  1V3B A;  4GZP A;  2BZD A;  1VCJ A;  3TI3 A;  2XCY A;  5HUG A;  4YW1 A;  1W21 A;  4GDI A;  2AGS A;  3TIB A;  4XIK A;  1MS1 A;  2SIL A;  1L7H A;  4GZX A;  2YDT A;  4FPK A;  3JU4 A;  4M4N A;  2HTV A;  2F12 A;  4FP2 A;  4MWX A;  3TIC A;  1Z4X A;  4K1I A;  2F10 A;  4HZZ A;  3CYE A;  3TI4 A;  2HT8 A;  2VW2 A;  4HZY A;  2QWH A;  1E8V A;  3GVK A;  3INB A;  2YA4 A;  4XJU A;  4GB1 A;  5M1Z A;  4FPJ A;  4SLI A;  4XJQ A;  1INV A;  4FOV A;  2HT5 A;  4K3Y A;  1F8E A;  2YA6 A;  1NNB A;  2YA8 A;  3O9K A;  1V3E A;  6NN9 A;  4MJV A;  4MWQ A;  2QWG A;  2W20 A;  4MWJ A;  4MZE A;  1NCD N;  2BER A;  3W09 A;  3A72 A;  4YW2 A;  4QNP A;  1XOE A;  4M4U A;  4B7J A;  2F26 A;  2HTW A;  3GVL A;  2HTU A;  3T1E A;  1S0J A;  3ALX A;  4CPN A;  2HTY A;  2X9M A;  4YW3 A;  1NCA N;  2XZJ A;  4MC7 A;  3H71 A;  4KS3 A;  1INW A;  5B2C A;  1NSB A;  4GJT A;  5B2D A;  4GZQ A;  1IVG A;  4QN3 A;  4DGR A;  1S0I A;  1EUS A;  4FP3 A;  2XZI A;  4NC5 A;  4GDJ A;  1DIL A;  2F24 A;  4MZA A;  4XIO A;  1MS5 A;  3D12 A;  4GZS A;  1N1V A;  1V2I A;  4FOQ A;  2C4L A;  3TI8 A;  1SLL A;  3K36 A;  4FZH A;  1A4Q A;  1NMA N;  4XOG A;  4CPO A;  1MS0 A;  1EUU A;  1V3D A;  1WCS A;  4XE9 A;  4UF7 A;  1IVE A;  3SIL A;  4HZW A;  4XMA A;  2HTQ A;  4FPL A;  4X4A A;  1ING A;  4YZ5 A;  1NNA A;  4FPE A;  4WA3 A;  2HT7 A;  4FPC A;  1V3C A;  1W1X A;  1W8O A;  3TI5 A;  1NMB N;  4KS1 A;  1SLI A;  4HZX A;  4KS2 A;  4FQ4 A;  5HX0 A;  1INY A;  7NN9 A;  4HIZ A;  2QWK A;  4XHB A;  4CPM A;  4GZO A;  1Z4Y A;  4NCS A;  4FOW A;  4MWV A;  2VW0 A;  2FHR A;  4MX0 A;  2F0Z A;  2ZB5 A;  4XMI A;  3PJQ A;  1F8D A;  1B9V A;  4YW5 A;  3K37 A;  3NN9 A;  3A71 A;  1INF A;  1INH A;  4K1J A;  3SAN A;  1W20 A;  4WEG A;  2QWA A; 
#chains in the Genus database with same CATH topology
 4MWU A;  4ZY3 A;  4L7D A;  4I00 A;  3KGG A;  2HU4 A;  4R40 A;  5JYY A;  1V0E A;  2VK6 A;  5FWW A;  4GZW A;  3BEQ A;  2VAQ A;  1IVC A;  5FNT A;  2YA7 A;  1W0P A;  4YZ2 A;  1W8N A;  3CKZ A;  4WEF A;  1IVD A;  2QWD A;  4M4V A;  4CPL A;  3H6J A;  1XOG A;  2XZK A;  4X6K A;  1V04 A;  2YA5 A;  1E8U A;  3AMR A;  4J9T A;  4YW4 A;  2IAR A;  3ALW A;  1QLG A;  2SLI A;  4NN9 A;  3CL0 A;  1E8T A;  4CPZ A;  1N1Y A;  1NCC N;  3IAX A;  1N1T A;  4A0P A;  1NSD A;  3B69 A;  5FZJ A;  1PJX A;  3DAS A;  4XJ9 A;  1NNC A;  3GVJ A;  2A75 A;  3K39 A;  3VNH A;  4B7N A;  4D8S A;  4XJA A;  4GZT A;  1A4G A;  3ZGC A;  3V65 B;  1QBI A;  4M3M A;  4UOU A;  4IQK A;  4AGI A;  3WN7 A;  2F13 A;  4Q6K A;  4QN5 A;  3WDZ A;  1MZ6 A;  4XHX A;  1EUR A;  2VVZ A;  3NSS A;  4HHO A;  1IVF A;  2OJH A;  4L7B A;  1SNT A;  1V0F A;  2QWE A;  4FJ6 A;  4MWY A;  1VCU A;  3CL2 A;  3D11 A;  2VK5 A;  4KS4 A;  4H53 A;  1MS3 A;  3G4H A;  4MWW A;  4GNB A;  4DG6 A;  1IVB A;  3AMS A;  3H73 A;  4B7M A;  4XYX A;  1RWI A;  2IAU A;  1WCQ A;  1Z50 A;  1USR A;  1N6F A;  1Z4V A;  4HZV A;  5HUN A;  2W5O A;  1OFZ A;  1MR5 A;  1B9S A;  3V1S A;  1INX A;  5NN9 A;  4K1H A;  2FP9 A;  4FPH A;  2YDP A;  4D52 A;  1NN2 A;  4D4U A;  2AEP A;  1ZGK A;  2B8H A;  1NSC A;  1L7G A;  1W0O A;  1H6L A;  1Z4W A;  2ZB6 A;  3FVZ A;  3P5B L;  5FNU A;  4H52 A;  1IJQ A;  4XJ8 A;  1MS8 A;  2RKC A;  3SLI A;  4FOY A;  4WA4 A;  1N6D A;  5CGJ A;  4FPF A;  4XJR A;  2VSM A;  3A9G A;  2F29 A;  2QWB A;  4X47 A;  2W5N A;  1F8B A;  4IFL X;  4WA5 A;  1USX A;  5FNQ A;  2F25 A;  2QWF A;  2W8B B;  3OPZ A;  2F27 A;  4G3N A;  4L7C A;  1B9T A;  2W38 A;  1RWL A;  4B7R A;  1CQ1 A;  2Z32 A;  4MWL A;  2JKB A;  3LI5 A;  4B7Q A;  5FNS A;  2VW1 A;  2CML A;  2SIM A;  1BJI A;  2V91 A;  5HUM A;  2C4A A;  4MWR A;  1MS9 A;  2AEQ A;  2IAV A;  3DR2 A;  3ZGD A;  3L6V A;  5D9B A;  3NO0 A;  3K38 A;  3TC9 A;  2QE8 A;  4FPY A;  2VSK A;  1NMC A;  3TI6 A;  3UC1 A;  1WP5 A;  2HU0 A;  3H72 A;  1MS4 A;  1EUT A;  2BAT A;  2F11 A;  4FVK A;  5HUK A;  1NCB N;  3Q6P A;  2AH2 A;  3ADE A;  3G4E A;  2FPB A;  4KS5 A;  4XJZ A;  4BBW A;  2ZW9 A;  2IAS A;  2VWD A;  3FW0 A;  4YZ1 A;  4GN8 A;  1KIT A;  3SAL A;  1E1A A;  1CRZ A;  1F8C A;  2HTR A;  4XIL A;  2G8S A;  1L7F A;  2QWI A;  3Q6T A;  4CPY A;  4QN6 A;  1N7D A;  3O9J A;  3HRP A;  5D9C A;  4QN4 A;  1N1S A;  2DG1 A;  2DSO A;  1SO7 A;  1V0Z A;  1Z4Z A;  4GEZ A;  3E5Z A;  4X49 A;  4JF7 A;  1A14 N;  2QWJ A;  3WW9 A;  4K1K A;  4QN7 A;  1MWE A;  1DIM A;  4XJW A;  2BF6 A;  4YZ3 A;  2W8B A;  1X2R A;  3Q6K A;  2F28 A;  5F9T A;  4GNC A;  2VK7 A;  4FPG A;  1MZ5 A;  2QWC A;  4MJU A;  4FPO B;  1IUC A;  3K3A A;  3B7E A;  3TIA A;  4YZ4 A;  2IAP A;  1V3B A;  2IAO A;  4C1Y B;  4GZP A;  2BZD A;  3A9H A;  5FNR A;  5GX2 A;  1VCJ A;  4GN7 A;  4IFN X;  3TI3 A;  2HQS A;  2XCY A;  4IYG A;  5HUG A;  4YW1 A;  2ZZK A;  3U0S A;  1W21 A;  3VNG A;  4GDI A;  2AGS A;  5EO7 A;  2ISM A;  3TIB A;  1CVM A;  4XIK A;  1MS1 A;  2SIL A;  4CH9 A;  1L7H A;  4GZX A;  5F72 C;  5EO8 A;  2YDT A;  4FPK A;  1S18 A;  4GN9 A;  3JU4 A;  4ZGC A;  4M4N A;  2HTV A;  2F12 A;  2GVW A;  3WWA A;  4FP2 A;  4AGT A;  4MWX A;  2H2N A;  2GVV A;  4O5S A;  3TIC A;  1Z4X A;  4N1B A;  4K1I A;  2DYH A;  2F10 A;  4D52 C;  3V64 C;  4HZZ A;  2GVX A;  2FLU X;  3CYE A;  3TI4 A;  2HT8 A;  2VW2 A;  4HZY A;  2QWH A;  2IVZ A;  1E8V A;  2GVU A;  3GVK A;  3INB A;  4ASC A;  3I1C A;  4IMB A;  2FPC A;  3SOB B;  2YA4 A;  4XJU A;  4GB1 A;  5M1Z A;  3SOQ A;  4FPJ A;  2DG0 A;  4SLI A;  4XJQ A;  1INV A;  4FOV A;  2HT5 A;  3SRE A;  4K3Y A;  1F8E A;  2YA6 A;  1NNB A;  2YA8 A;  3O9K A;  4ZLR A;  1V3E A;  6NN9 A;  5GX1 A;  4MJV A;  4MWQ A;  2QWG A;  2W20 A;  4MWJ A;  4MZE A;  1NCD N;  3S2K A;  2BER A;  3W09 A;  3A72 A;  2XN4 A;  4YW2 A;  3II7 A;  4QNP A;  1XOE A;  4M4U A;  4B7J A;  2F26 A;  5GX3 A;  2HTW A;  3GVL A;  2HTU A;  1C9U A;  3T1E A;  4AH4 A;  1CRU A;  1S0J A;  4IFJ A;  3ALX A;  5FZN A;  4CPN A;  2HTY A;  2X9M A;  4YW3 A;  1NCA N;  5GX5 A;  2XZJ A;  3BYC A;  4MC7 A;  3H71 A;  4KS3 A;  3LI4 A;  3KYA A;  1INW A;  2POO A;  5B2C A;  1NSB A;  3LI3 A;  4GJT A;  3SOV A;  4D52 B;  2IAQ A;  4CHB A;  2IAX A;  5B2D A;  4GZQ A;  1IVG A;  4QN3 A;  2IAW A;  4DGR A;  1S0I A;  1EUS A;  4FP3 A;  1Q7F A;  2XZI A;  4NC5 A;  4GDJ A;  1DIL A;  3SRG A;  2IAT A;  2F24 A;  4HW6 A;  4MZA A;  4XIO A;  1MS5 A;  3D12 A;  3S8Z A;  1POO A;  4GZS A;  5GTQ A;  1N1V A;  1V2I A;  4FOQ A;  2C4L A;  4Q1U A;  3TI8 A;  1SLL A;  3K36 A;  5GX4 A;  4FZH A;  1A4Q A;  3HLH A;  1NMA N;  4XOG A;  1SUU A;  4IN4 A;  4O5T A;  1C5K A;  4CPO A;  3O4P A;  1MS0 A;  2ZWA A;  1EUU A;  1V3D A;  1WCS A;  4XE9 A;  4UF7 A;  1IVE A;  3S94 A;  3SIL A;  4HZW A;  4XMA A;  2HTQ A;  1IUB A;  2GHS A;  1K32 A;  4FPL A;  4X4A A;  1ING A;  4YZ5 A;  2FP8 A;  1NNA A;  4FPE A;  1X2J A;  2HT7 A;  2VPJ A;  4WA3 A;  4FPC A;  1V3C A;  1W1X A;  1W8O A;  4GNA A;  1N6E A;  3TI5 A;  2P4O A;  1NMB N;  3S8V A;  4KS1 A;  1SLI A;  1U6D X;  4PWZ A;  4HZX A;  4KS2 A;  4FQ4 A;  5HX0 A;  1INY A;  7NN9 A;  4HIZ A;  2QWK A;  4XHB A;  4CPM A;  1NPE A;  4GZO A;  1Z4Y A;  4NCS A;  4FOW A;  4MWV A;  3HLI A;  4XMB A;  2WOZ A;  2VW0 A;  4AHA A;  2FHR A;  4HHQ A;  2F0Z A;  4MX0 A;  4JML A;  2ZB5 A;  4XMI A;  5H47 A;  3PJQ A;  2H2U A;  1F8D A;  1B9V A;  5EX7 A;  4C1Y A;  4YW5 A;  5D9D A;  4YY8 A;  3K37 A;  3NN9 A;  4CSD A;  3A71 A;  1INF A;  1S1D A;  1INH A;  4K1J A;  3SAN A;  1W20 A;  4WEG A;  2QWA A;  1ZI0 A; 
#chains in the Genus database with same CATH homology
 4MWU A;  4I00 A;  2HU4 A;  5JYY A;  1V0E A;  2VK6 A;  4GZW A;  3BEQ A;  1IVC A;  2YA7 A;  1W0P A;  4YZ2 A;  1W8N A;  3CKZ A;  4WEF A;  1IVD A;  2QWD A;  4M4V A;  4CPL A;  3H6J A;  1XOG A;  2XZK A;  4X6K A;  2YA5 A;  1E8U A;  4J9T A;  4YW4 A;  3ALW A;  2SLI A;  4NN9 A;  3CL0 A;  1E8T A;  4CPZ A;  1N1Y A;  1NCC N;  1N1T A;  1NSD A;  3B69 A;  4XJ9 A;  1NNC A;  3GVJ A;  2A75 A;  3K39 A;  4B7N A;  4D8S A;  4XJA A;  4GZT A;  1A4G A;  4M3M A;  2F13 A;  4Q6K A;  4QN5 A;  1MZ6 A;  4XHX A;  1EUR A;  2VVZ A;  3NSS A;  1IVF A;  1SNT A;  1V0F A;  2QWE A;  4FJ6 A;  4MWY A;  1VCU A;  3CL2 A;  3D11 A;  2VK5 A;  4KS4 A;  4H53 A;  1MS3 A;  4MWW A;  1IVB A;  3H73 A;  4B7M A;  4XYX A;  1WCQ A;  1Z50 A;  1USR A;  1Z4V A;  4HZV A;  5HUN A;  2W5O A;  1MR5 A;  1B9S A;  1INX A;  5NN9 A;  4K1H A;  4FPH A;  2YDP A;  1NN2 A;  2AEP A;  2B8H A;  1NSC A;  1L7G A;  1W0O A;  2ZB6 A;  1Z4W A;  4H52 A;  4XJ8 A;  1MS8 A;  2RKC A;  3SLI A;  4FOY A;  4WA4 A;  4FPF A;  4XJR A;  2VSM A;  2F29 A;  2QWB A;  4X47 A;  2W5N A;  1F8B A;  4WA5 A;  1USX A;  2F25 A;  2QWF A;  3OPZ A;  2F27 A;  1B9T A;  2W38 A;  4B7R A;  4MWL A;  2JKB A;  4B7Q A;  2VW1 A;  2CML A;  2SIM A;  1BJI A;  5HUM A;  2C4A A;  4MWR A;  1MS9 A;  2AEQ A;  3K38 A;  4FPY A;  2VSK A;  1NMC A;  3TI6 A;  2HU0 A;  3H72 A;  1MS4 A;  1EUT A;  2BAT A;  2F11 A;  4FVK A;  5HUK A;  1NCB N;  2AH2 A;  4KS5 A;  4XJZ A;  4BBW A;  2VWD A;  4YZ1 A;  1KIT A;  3SAL A;  1F8C A;  2HTR A;  4XIL A;  1L7F A;  2QWI A;  4CPY A;  4QN6 A;  3O9J A;  4QN4 A;  1N1S A;  1SO7 A;  1V0Z A;  1Z4Z A;  4GEZ A;  4X49 A;  4JF7 A;  1A14 N;  2QWJ A;  4K1K A;  4QN7 A;  1MWE A;  1DIM A;  4XJW A;  2BF6 A;  4YZ3 A;  2F28 A;  5F9T A;  2VK7 A;  4FPG A;  1MZ5 A;  2QWC A;  4MJU A;  4FPO B;  3K3A A;  3B7E A;  3TIA A;  4YZ4 A;  1V3B A;  4GZP A;  2BZD A;  1VCJ A;  3TI3 A;  2XCY A;  5HUG A;  4YW1 A;  1W21 A;  4GDI A;  2AGS A;  3TIB A;  4XIK A;  1MS1 A;  2SIL A;  1L7H A;  4GZX A;  2YDT A;  4FPK A;  1S18 A;  3JU4 A;  4M4N A;  2HTV A;  2F12 A;  4FP2 A;  4MWX A;  2H2N A;  3TIC A;  1Z4X A;  4K1I A;  2F10 A;  4HZZ A;  3CYE A;  3TI4 A;  2HT8 A;  2VW2 A;  4HZY A;  2QWH A;  1E8V A;  3GVK A;  3INB A;  2YA4 A;  4XJU A;  4GB1 A;  5M1Z A;  4FPJ A;  4SLI A;  4XJQ A;  1INV A;  4FOV A;  2HT5 A;  4K3Y A;  1F8E A;  2YA6 A;  1NNB A;  2YA8 A;  3O9K A;  1V3E A;  6NN9 A;  4MJV A;  4MWQ A;  2QWG A;  2W20 A;  4MWJ A;  4MZE A;  1NCD N;  2BER A;  3W09 A;  3A72 A;  4YW2 A;  4QNP A;  1XOE A;  4M4U A;  4B7J A;  2F26 A;  2HTW A;  3GVL A;  2HTU A;  3T1E A;  1S0J A;  3ALX A;  4CPN A;  2HTY A;  2X9M A;  4YW3 A;  1NCA N;  2XZJ A;  4MC7 A;  3H71 A;  4KS3 A;  1INW A;  5B2C A;  1NSB A;  4GJT A;  5B2D A;  4GZQ A;  1IVG A;  4QN3 A;  4DGR A;  1S0I A;  1EUS A;  4FP3 A;  2XZI A;  4NC5 A;  4GDJ A;  1DIL A;  2F24 A;  4MZA A;  4XIO A;  1MS5 A;  3D12 A;  4GZS A;  1N1V A;  1V2I A;  4FOQ A;  2C4L A;  3TI8 A;  1SLL A;  3K36 A;  4FZH A;  1A4Q A;  1NMA N;  4XOG A;  4CPO A;  1MS0 A;  1EUU A;  1V3D A;  1WCS A;  4XE9 A;  4UF7 A;  1IVE A;  3SIL A;  4HZW A;  4XMA A;  2HTQ A;  4FPL A;  4X4A A;  1ING A;  4YZ5 A;  1NNA A;  4FPE A;  4WA3 A;  2HT7 A;  4FPC A;  1V3C A;  1W1X A;  1W8O A;  3TI5 A;  1NMB N;  4KS1 A;  1SLI A;  4HZX A;  4KS2 A;  4FQ4 A;  5HX0 A;  1INY A;  7NN9 A;  4HIZ A;  2QWK A;  4XHB A;  4CPM A;  4GZO A;  1Z4Y A;  4NCS A;  4FOW A;  4MWV A;  2VW0 A;  2FHR A;  4MX0 A;  2F0Z A;  2ZB5 A;  4XMI A;  3PJQ A;  2H2U A;  1F8D A;  1B9V A;  4YW5 A;  3K37 A;  3NN9 A;  3A71 A;  1INF A;  1S1D A;  1INH A;  4K1J A;  3SAN A;  1W20 A;  4WEG A;  2QWA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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