2F29A

Crystal structure of the human sialidase neu2 q116e mutant in complex with dana inhibitor
Total Genus 90
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
377
structure length
370
Chain Sequence
MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTEQQQLETRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLNDRARSLVVPAYAYRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVEQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSPAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAEY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Human Sialidase Neu2 Q116E Mutant in Complex with DANA Inhibitor
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Sialidase 2
total genus 90
structure length 370
sequence length 377
chains with identical sequence B
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 2005-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13088 BNR_2 BNR repeat-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 2f29A00
1NCAN 4CPZA 6NN9A 4XE9A 1W0OA 1VCJA 4M4UA 3BEQA 1EUUA 1MWEA 4HZWA 4MJUA 4XOGA 1W20A 4HZZA 1W8NA 4M4NA 7NN9A 1W21A 3K38A 3H6JA 4MZAA 2FHRA 1IVBA 1XOGA 1V3BA 1N1TA 4FJ6A 4XJ8A 1V0FA 2HTUA 1MS3A 4GZXA 2B8HA 2QWFA 2HU0A 2QWCA 3TIBA 2BATA 2SIMA 4XJRA 2F13A 4YZ2A 2HTVA 4K3YA 1INWA 1Z4XA 1DIMA 1MS8A 2F12A 1V0ZA 2BF6A 4H52A 3D11A 4FOQA 4FPKA 4HIZA 1NNAA 3CKZA 1V3DA 4MC7A 4CPNA 1USRA 2ZB5A 4M4VA 4K1KA 4X6KA 4FPJA 1Z4VA 4FPEA 3W09A 2W38A 4GZPA 3B7EA 4I00A 1B9SA 4MWLA 4GZWA 4MWXA 2XCYA 1INGA 1F8EA 2AGSA 3D12A 4GZQA 4WEFA 4XJAA 2QWDA 4B7QA 2AEPA 4KS4A 1B9TA 3INBA 2HTQA 4KS2A 4J9TA 2QWJA 3SALA 2W5NA 3K37A 1INVA 4GB1A 1INHA 4XJQA 2QWGA 4MWUA 1EUSA 4MWYA 4QN4A 4BBWA 3SLIA 1MS1A 1MS5A 1V2IA 1NCDN 1NSCA 3T1EA 3TI8A 3A72A 3GVLA 4YZ5A 5HUKA 1INXA 1V3CA 4FVKA 3H73A 1N1VA 1Z50A 1USXA 3CL2A 4FPLA 2AEQA 2HU4A 4YZ3A 2RKCA 4FPOB 1Z4ZA 1MZ6A 3ALXA 2QWHA 5B2DA 1NCBN 4FQ4A 1MS4A 3GVJA 4FPYA 4WA5A 1N1SA 2W5OA 5JYYA 2SLIA 4XJ9A 4YW1A 2F29A 1S0JA 1F8BA 2VK7A 1NCCN 2XZIA 1SO7A 4B7MA 4B7JA 1WCQA 2VVZA 2BERA 4CPYA 1NN2A 4QN7A 4Q6KA 4D8SA 2YA4A 4YW5A 3B69A 2HT8A 4MZEA 4UF7A 1NMBN 1A4GA 2JKBA 2F0ZA 4FOYA 4QN3A 1NSDA 4FOWA 1IVDA 2YA8A 2VW1A 3TI6A 2F11A 3TICA 1Z4WA 2F27A 2F26A 4K1HA 4KS5A 4CPLA 4WA3A 2F24A 2QWAA 4XHXA 4WA4A 2VSMA 2F28A 4YZ4A 5NN9A 4NC5A 4MJVA 2QWIA 4M3MA 3ALWA 1N1YA 3CL0A 4MWWA 1S0IA 3SILA 4GDJA 4GEZA 3K36A 4FPGA 2QWBA 4HZXA 4KS3A 2HTYA 3NSSA 1VCUA 4B7RA 3H71A 2C4LA 2XZKA 3JU4A 1NMCA 4DGRA 4XIOA 4YZ1A 4XJUA 4QNPA 2W20A 1NNCA 2ZB6A 1L7GA 3NN9A 2VK5A 5HUMA 1E8TA 1INFA 4MWRA 4HZYA 1SLLA 4CPMA 2F25A 2XZJA 4GZOA 4FP3A 2VW2A 4XILA 2SILA 3K3AA 4KS1A 2HTWA 2HT7A 4MWVA 1KITA 1INYA 1IVFA 1V0EA 1A4QA 2YDPA 4GZTA 1Z4YA 2VWDA 2YDTA 1F8CA 4YW4A 4K1IA 1XOEA 4CPOA 2QWEA 2A75A 2QWKA 4X4AA 1NMAN 1V3EA 2HTRA 1NSBA 1L7FA 4MWJA 1MS0A 5HX0A 4FPHA 3TI5A 1WCSA 1L7HA 2VSKA 4FP2A 4NCSA 1W1XA 1NNBA 3H72A 1W0PA 1SLIA 3GVKA 4XHBA 5HUNA 1F8DA 4HZVA 4YW3A 4NN9A 2CMLA 4XJZA 1A14N 1DILA 3O9KA 4XYXA 4X49A 4FPCA 5M1ZA 1E8UA 2C4AA 3TIAA 1EUTA 2F10A 3K39A 5B2CA 1W8OA 1SNTA 4K1JA 1E8VA 4JF7A 4XJWA 4H53A 5HUGA 4QN5A 4XIKA 4X47A 2YA5A 4XMAA 4GZSA 3A71A 1MS9A 3OPZA 1MR5A 3CYEA 1IVEA 4GDIA 1IVCA 4GJTA 1BJIA 2X9MA 3SANA 3TI4A 2VK6A 4QN6A 4FZHA 3TI3A 2YA7A 2HT5A 1MZ5A 4SLIA 1IVGA 1EURA 3O9JA 4FOVA 4FPFA 5F9TA 3PJQA 4MX0A 1B9VA 2AH2A 2VW0A 4WEGA 4MWQA 4B7NA 4XMIA 4YW2A 2YA6A 2BZDA
chains in the Genus database with same CATH superfamily
1NCAN 4CPZA 6NN9A 1NPEA 3I1CA 4XE9A 1W0OA 1ZGKA 3Q6KA 4C1YB 1VCJA 1IJQA 4M4UA 5D9CA 5FWWA 3BEQA 1EUUA 1MWEA 4HZWA 4MJUA 4XOGA 1W20A 4HZZA 2W8BA 1W8NA 5F72C 4M4NA 7NN9A 1W21A 3K38A 3H6JA 1S1DA 3DR2A 2W8BB 3LI3A 4MZAA 2FHRA 1IVBA 1XOGA 1V3BA 1N1TA 4FJ6A 1RWLA 4XJ8A 1V0FA 2HTUA 1MS3A 4GZXA 2B8HA 2QWFA 2HU0A 2QWCA 3TIBA 2BATA 2P4OA 2SIMA 4XJRA 4AHAA 2F13A 5EO8A 4YZ2A 2HTVA 4K3YA 2ISMA 2ZZKA 1INWA 1Z4XA 1DIMA 1MS8A 2F12A 2FLUX 1V0ZA 2BF6A 4H52A 3D11A 1Q7FA 2IATA 4FOQA 4FPKA 4HIZA 1NNAA 3CKZA 2Z32A 1V3DA 4MC7A 5FZJA 1USRA 4CPNA 2ZB5A 4M4VA 4K1KA 4X6KA 1QLGA 4FPJA 1Z4VA 4IYGA 4DG6A 4FPEA 3W09A 2W38A 4GZPA 3B7EA 4I00A 5FNSA 1B9SA 4MWLA 4GZWA 4MWXA 4D4UA 2XCYA 5CGJA 1INGA 1F8EA 2QE8A 4IMBA 1E1AA 2AGSA 3D12A 4O5SA 4GZQA 4WEFA 1C5KA 1CRZA 4XJAA 2QWDA 1IUBA 4B7QA 4ASCA 2AEPA 4KS4A 1B9TA 3SOVA 3INBA 2HTQA 4KS2A 4JMLA 4J9TA 2QWJA 3SALA 2GVWA 2W5NA 1ZI0A 2VAQA 5FNQA 3K37A 1INVA 3U0SA 4GB1A 1INHA 4XJQA 4ZGCA 2QWGA 4MWUA 1EUSA 4MWYA 3WDZA 2IVZA 3V65B 3II7A 4QN4A 4BBWA 2IAWA 3SLIA 1MS1A 3L6VA 4HHQA 1MS5A 1NCDN 1NSCA 1V2IA 3T1EA 2DYHA 3LI5A 3TI8A 2ZW9A 3A72A 3GVLA 1SUUA 4IFLX 4YZ5A 5HUKA 3SOQA 3ADEA 1INXA 1V3CA 2IAVA 4FVKA 3H73A 1N1VA 1Z50A 5EO7A 1USXA 3SREA 3CL2A 4FPLA 2AEQA 2HU4A 3O4PA 3E5ZA 4YZ3A 5GX3A 2RKCA 2FPBA 4FPOB 1Z4ZA 4Q1UA 1MZ6A 2IARA 4IN4A 3ALXA 1S18A 2QWHA 5EX7A 5B2DA 1NCBN 4FQ4A 1MS4A 3LI4A 3GVJA 4FPYA 4WA5A 1N1SA 5FNTA 2W5OA 5JYYA 3KYAA 2SLIA 4CSDA 1QBIA 4GN7A 4XJ9A 2IAQA 4YW1A 3FW0A 2F29A 1S0JA 3HLIA 1F8BA 2VK7A 1NCCN 4ZLRA 5D9BA 2XZIA 1SO7A 4B7MA 2V91A 4B7JA 3G4HA 1WCQA 2VVZA 2BERA 3HLHA 4CPYA 1NN2A 4QN7A 3FVZA 4Q6KA 4HHOA 4D8SA 2YA4A 4YW5A 3B69A 2HT8A 4MZEA 4UF7A 1NMBN 1A4GA 4D52A 2DG1A 2JKBA 1H6LA 2F0ZA 2POOA 4FOYA 4GNAA 4AH4A 4QN3A 1NSDA 4FOWA 4CHBA 1IVDA 3S8ZA 4D52B 2YA8A 2VW1A 3TI6A 2F11A 3TICA 1IUCA 1Z4WA 2F27A 2FP8A 2F26A 4K1HA 1N7DA 4KS5A 4CPLA 4WA3A 2F24A 2IASA 1U6DX 2QWAA 4XHXA 4WA4A 2VSMA 2F28A 4YZ4A 3UC1A 5NN9A 4NC5A 4MJVA 2QWIA 4M3MA 3ALWA 1N1YA 3CL0A 4MWWA 1S0IA 3SILA 4GDJA 1RWIA 3K36A 4GEZA 4FPGA 2QWBA 4HZXA 3SOBB 3ZGDA 4KS3A 2GVUA 2HTYA 3NSSA 3WW9A 1VCUA 3BYCA 3HRPA 4B7RA 1C9UA 3V64C 2ZWAA 3H71A 4C1YA 2C4LA 5D9DA 4GN9A 2H2UA 2XZKA 3JU4A 1NMCA 4DGRA 4IFJA 4XIOA 4YZ1A 1K32A 1X2RA 4XJUA 3VNHA 4QNPA 2G8SA 2W20A 1NNCA 5FZNA 2ZB6A 4GN8A 4IFNX 5FNUA 1CRUA 1L7GA 3NN9A 2VK5A 5HUMA 1E8TA 3Q6PA 2H2NA 2XN4A 1INFA 2WOZA 4MWRA 4HZYA 1SLLA 2OJHA 5GTQA 4CPMA 2DG0A 2F25A 4L7DA 2XZJA 5GX2A 4GZOA 4FP3A 1CQ1A 2VW2A 4XILA 2SILA 3K3AA 4KS1A 5GX1A 2HTWA 2HT7A 4MWVA 3S2KA 1KITA 4CH9A 1INYA 1IVFA 1N6EA 1V0EA 1A4QA 3S94A 4PWZA 1V04A 2YDPA 4GNBA 4L7CA 4GZTA 1Z4YA 2VWDA 2YDTA 1F8CA 4XMBA 4YW4A 3V1SA 4K1IA 1XOEA 3A9HA 3VNGA 4CPOA 2FPCA 2QWEA 4IQKA 5H47A 2A75A 2QWKA 4X4AA 1NMAN 1V3EA 3ZGCA 2HTRA 1NSBA 1PJXA 2IAXA 1L7FA 3S8VA 4GNCA 4MWJA 1MS0A 1X2JA 3WN7A 4D52C 5HX0A 4FPHA 3TI5A 1WCSA 1L7HA 2DSOA 3G4EA 3DASA 2VSKA 4AGTA 4FP2A 4NCSA 3WWAA 1W1XA 1NNBA 2IAUA 3H72A 1W0PA 1SLIA 3GVKA 1WP5A 4XHBA 5HUNA 1F8DA 4HZVA 4YW3A 5FNRA 4NN9A 2IAOA 2CMLA 4XJZA 5GX5A 3P5BL 1A14N 1DILA 3O9KA 3IAXA 4XYXA 3TC9A 4X49A 4FPCA 5M1ZA 1POOA 4HW6A 1N6FA 1N6DA 1E8UA 1OFZA 2C4AA 3TIAA 1EUTA 4L7BA 2F10A 4ZY3A 3SRGA 4YY8A 3K39A 5B2CA 1W8OA 3KGGA 1SNTA 4K1JA 1E8VA 3Q6TA 4UOUA 4A0PA 4JF7A 4R40A 4XJWA 4H53A 5HUGA 4QN5A 4XIKA 4X47A 2YA5A 4N1BA 4XMAA 4GZSA 3AMRA 5GX4A 3A71A 1MS9A 3OPZA 1MR5A 3CYEA 1IVEA 4GDIA 4O5TA 1IVCA 2GHSA 3AMSA 3NO0A 4G3NA 4GJTA 1BJIA 3A9GA 2HQSA 2X9MA 3SANA 3TI4A 2VK6A 4QN6A 4FZHA 3TI3A 2IAPA 2YA7A 2HT5A 1MZ5A 4SLIA 1IVGA 1EURA 2GVVA 3O9JA 4FOVA 4FPFA 1CVMA 5F9TA 3PJQA 4MX0A 1B9VA 2AH2A 2FP9A 2VPJA 2VW0A 4WEGA 4MWQA 4B7NA 4AGIA 4XMIA 4YW2A 2YA6A 2GVXA 2BZDA
chains in the Genus database with same CATH topology
1NCAN 4CPZA 6NN9A 4XE9A 1W0OA 1VCJA 4M4UA 3BEQA 1EUUA 1MWEA 4HZWA 4MJUA 4XOGA 1W20A 4HZZA 1W8NA 4M4NA 7NN9A 1W21A 3K38A 3H6JA 1S1DA 4MZAA 2FHRA 1IVBA 1XOGA 1V3BA 1N1TA 4FJ6A 4XJ8A 1V0FA 2HTUA 1MS3A 4GZXA 2B8HA 2QWFA 2HU0A 2QWCA 3TIBA 2BATA 2SIMA 4XJRA 2F13A 4YZ2A 2HTVA 4K3YA 1INWA 1Z4XA 1DIMA 1MS8A 2F12A 1V0ZA 2BF6A 4H52A 3D11A 4FOQA 4FPKA 4HIZA 1NNAA 3CKZA 1V3DA 4MC7A 4CPNA 1USRA 2ZB5A 4M4VA 4K1KA 4X6KA 4FPJA 1Z4VA 4FPEA 3W09A 2W38A 4GZPA 3B7EA 4I00A 1B9SA 4MWLA 4GZWA 4MWXA 2XCYA 1INGA 1F8EA 2AGSA 3D12A 4GZQA 4WEFA 4XJAA 2QWDA 4B7QA 2AEPA 4KS4A 1B9TA 3INBA 2HTQA 4KS2A 4J9TA 2QWJA 3SALA 2W5NA 3K37A 1INVA 4GB1A 1INHA 4XJQA 2QWGA 4MWUA 1EUSA 4MWYA 4QN4A 4BBWA 3SLIA 1MS1A 1MS5A 1V2IA 1NCDN 1NSCA 3T1EA 3TI8A 3A72A 3GVLA 4YZ5A 5HUKA 1INXA 1V3CA 4FVKA 3H73A 1N1VA 1Z50A 1USXA 3CL2A 4FPLA 2AEQA 2HU4A 4YZ3A 2RKCA 4FPOB 1Z4ZA 1MZ6A 3ALXA 1S18A 2QWHA 5B2DA 1NCBN 4FQ4A 1MS4A 3GVJA 4FPYA 4WA5A 1N1SA 2W5OA 5JYYA 2SLIA 4XJ9A 4YW1A 2F29A 1S0JA 1F8BA 2VK7A 1NCCN 2XZIA 1SO7A 4B7MA 4B7JA 1WCQA 2VVZA 2BERA 4CPYA 1NN2A 4QN7A 4Q6KA 4D8SA 2YA4A 4YW5A 3B69A 2HT8A 4MZEA 4UF7A 1NMBN 1A4GA 2JKBA 2F0ZA 4FOYA 4QN3A 1NSDA 4FOWA 1IVDA 2YA8A 2VW1A 3TI6A 2F11A 3TICA 1Z4WA 2F27A 2F26A 4K1HA 4KS5A 4CPLA 4WA3A 2F24A 2QWAA 4XHXA 4WA4A 2VSMA 2F28A 4YZ4A 5NN9A 4NC5A 4MJVA 2QWIA 4M3MA 3ALWA 1N1YA 3CL0A 4MWWA 1S0IA 3SILA 4GDJA 4GEZA 3K36A 4FPGA 2QWBA 4HZXA 4KS3A 2HTYA 3NSSA 1VCUA 4B7RA 3H71A 2C4LA 2H2UA 2XZKA 3JU4A 1NMCA 4DGRA 4XIOA 4YZ1A 4XJUA 4QNPA 2W20A 1NNCA 2ZB6A 1L7GA 3NN9A 2VK5A 5HUMA 1E8TA 2H2NA 1INFA 4MWRA 4HZYA 1SLLA 4CPMA 2F25A 2XZJA 4GZOA 4FP3A 2VW2A 4XILA 2SILA 3K3AA 4KS1A 2HTWA 2HT7A 4MWVA 1KITA 1INYA 1IVFA 1V0EA 1A4QA 2YDPA 4GZTA 1Z4YA 2VWDA 2YDTA 1F8CA 4YW4A 4K1IA 1XOEA 4CPOA 2QWEA 2A75A 2QWKA 4X4AA 1NMAN 1V3EA 2HTRA 1NSBA 1L7FA 4MWJA 1MS0A 5HX0A 4FPHA 3TI5A 1WCSA 1L7HA 2VSKA 4FP2A 4NCSA 1W1XA 1NNBA 3H72A 1W0PA 1SLIA 3GVKA 4XHBA 5HUNA 1F8DA 4HZVA 4YW3A 4NN9A 2CMLA 4XJZA 1A14N 1DILA 3O9KA 4XYXA 4X49A 4FPCA 5M1ZA 1E8UA 2C4AA 3TIAA 1EUTA 2F10A 3K39A 5B2CA 1W8OA 1SNTA 4K1JA 1E8VA 4JF7A 4XJWA 4H53A 5HUGA 4QN5A 4XIKA 4X47A 2YA5A 4XMAA 4GZSA 3A71A 1MS9A 3OPZA 1MR5A 3CYEA 1IVEA 4GDIA 1IVCA 4GJTA 1BJIA 2X9MA 3SANA 3TI4A 2VK6A 4QN6A 4FZHA 3TI3A 2YA7A 2HT5A 1MZ5A 4SLIA 1IVGA 1EURA 3O9JA 4FOVA 4FPFA 5F9TA 3PJQA 4MX0A 1B9VA 2AH2A 2VW0A 4WEGA 4MWQA 4B7NA 4XMIA 4YW2A 2YA6A 2BZDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NCA N;  4CPZ A;  6NN9 A;  4XE9 A;  1W0O A;  1VCJ A;  4M4U A;  3BEQ A;  1EUU A;  1MWE A;  4HZW A;  4MJU A;  4XOG A;  1W20 A;  4HZZ A;  1W8N A;  4M4N A;  7NN9 A;  1W21 A;  3K38 A;  3H6J A;  4MZA A;  2FHR A;  1IVB A;  1XOG A;  1V3B A;  1N1T A;  4FJ6 A;  4XJ8 A;  1V0F A;  2HTU A;  1MS3 A;  4GZX A;  2B8H A;  2QWF A;  2HU0 A;  2QWC A;  3TIB A;  2BAT A;  2SIM A;  4XJR A;  2F13 A;  4YZ2 A;  2HTV A;  4K3Y A;  1INW A;  1Z4X A;  1DIM A;  1MS8 A;  2F12 A;  1V0Z A;  2BF6 A;  4H52 A;  3D11 A;  4FOQ A;  4FPK A;  4HIZ A;  1NNA A;  3CKZ A;  1V3D A;  4MC7 A;  4CPN A;  1USR A;  2ZB5 A;  4M4V A;  4K1K A;  4X6K A;  4FPJ A;  1Z4V A;  4FPE A;  3W09 A;  2W38 A;  4GZP A;  3B7E A;  4I00 A;  1B9S A;  4MWL A;  4GZW A;  4MWX A;  2XCY A;  1ING A;  1F8E A;  2AGS A;  3D12 A;  4GZQ A;  4WEF A;  4XJA A;  2QWD A;  4B7Q A;  2AEP A;  4KS4 A;  1B9T A;  3INB A;  2HTQ A;  4KS2 A;  4J9T A;  2QWJ A;  3SAL A;  2W5N A;  3K37 A;  1INV A;  4GB1 A;  1INH A;  4XJQ A;  2QWG A;  4MWU A;  1EUS A;  4MWY A;  4QN4 A;  4BBW A;  3SLI A;  1MS1 A;  1MS5 A;  1V2I A;  1NCD N;  1NSC A;  3T1E A;  3TI8 A;  3A72 A;  3GVL A;  4YZ5 A;  5HUK A;  1INX A;  1V3C A;  4FVK A;  3H73 A;  1N1V A;  1Z50 A;  1USX A;  3CL2 A;  4FPL A;  2AEQ A;  2HU4 A;  4YZ3 A;  2RKC A;  4FPO B;  1Z4Z A;  1MZ6 A;  3ALX A;  2QWH A;  5B2D A;  1NCB N;  4FQ4 A;  1MS4 A;  3GVJ A;  4FPY A;  4WA5 A;  1N1S A;  2W5O A;  5JYY A;  2SLI A;  4XJ9 A;  4YW1 A;  2F29 A;  1S0J A;  1F8B A;  2VK7 A;  1NCC N;  2XZI A;  1SO7 A;  4B7M A;  4B7J A;  1WCQ A;  2VVZ A;  2BER A;  4CPY A;  1NN2 A;  4QN7 A;  4Q6K A;  4D8S A;  2YA4 A;  4YW5 A;  3B69 A;  2HT8 A;  4MZE A;  4UF7 A;  1NMB N;  1A4G A;  2JKB A;  2F0Z A;  4FOY A;  4QN3 A;  1NSD A;  4FOW A;  1IVD A;  2YA8 A;  2VW1 A;  3TI6 A;  2F11 A;  3TIC A;  1Z4W A;  2F27 A;  2F26 A;  4K1H A;  4KS5 A;  4CPL A;  4WA3 A;  2F24 A;  2QWA A;  4XHX A;  4WA4 A;  2VSM A;  2F28 A;  4YZ4 A;  5NN9 A;  4NC5 A;  4MJV A;  2QWI A;  4M3M A;  3ALW A;  1N1Y A;  3CL0 A;  4MWW A;  1S0I A;  3SIL A;  4GDJ A;  4GEZ A;  3K36 A;  4FPG A;  2QWB A;  4HZX A;  4KS3 A;  2HTY A;  3NSS A;  1VCU A;  4B7R A;  3H71 A;  2C4L A;  2XZK A;  3JU4 A;  1NMC A;  4DGR A;  4XIO A;  4YZ1 A;  4XJU A;  4QNP A;  2W20 A;  1NNC A;  2ZB6 A;  1L7G A;  3NN9 A;  2VK5 A;  5HUM A;  1E8T A;  1INF A;  4MWR A;  4HZY A;  1SLL A;  4CPM A;  2F25 A;  2XZJ A;  4GZO A;  4FP3 A;  2VW2 A;  4XIL A;  2SIL A;  3K3A A;  4KS1 A;  2HTW A;  2HT7 A;  4MWV A;  1KIT A;  1INY A;  1IVF A;  1V0E A;  1A4Q A;  2YDP A;  4GZT A;  1Z4Y A;  2VWD A;  2YDT A;  1F8C A;  4YW4 A;  4K1I A;  1XOE A;  4CPO A;  2QWE A;  2A75 A;  2QWK A;  4X4A A;  1NMA N;  1V3E A;  2HTR A;  1NSB A;  1L7F A;  4MWJ A;  1MS0 A;  5HX0 A;  4FPH A;  3TI5 A;  1WCS A;  1L7H A;  2VSK A;  4FP2 A;  4NCS A;  1W1X A;  1NNB A;  3H72 A;  1W0P A;  1SLI A;  3GVK A;  4XHB A;  5HUN A;  1F8D A;  4HZV A;  4YW3 A;  4NN9 A;  2CML A;  4XJZ A;  1A14 N;  1DIL A;  3O9K A;  4XYX A;  4X49 A;  4FPC A;  5M1Z A;  1E8U A;  2C4A A;  3TIA A;  1EUT A;  2F10 A;  3K39 A;  5B2C A;  1W8O A;  1SNT A;  4K1J A;  1E8V A;  4JF7 A;  4XJW A;  4H53 A;  5HUG A;  4QN5 A;  4XIK A;  4X47 A;  2YA5 A;  4XMA A;  4GZS A;  3A71 A;  1MS9 A;  3OPZ A;  1MR5 A;  3CYE A;  1IVE A;  4GDI A;  1IVC A;  4GJT A;  1BJI A;  2X9M A;  3SAN A;  3TI4 A;  2VK6 A;  4QN6 A;  4FZH A;  3TI3 A;  2YA7 A;  2HT5 A;  1MZ5 A;  4SLI A;  1IVG A;  1EUR A;  3O9J A;  4FOV A;  4FPF A;  5F9T A;  3PJQ A;  4MX0 A;  1B9V A;  2AH2 A;  2VW0 A;  4WEG A;  4MWQ A;  4B7N A;  4XMI A;  4YW2 A;  2YA6 A;  2BZD A; 
#chains in the Genus database with same CATH topology
 1NCA N;  4CPZ A;  6NN9 A;  1NPE A;  3I1C A;  4XE9 A;  1W0O A;  1ZGK A;  3Q6K A;  4C1Y B;  1VCJ A;  1IJQ A;  4M4U A;  5D9C A;  5FWW A;  3BEQ A;  1EUU A;  1MWE A;  4HZW A;  4MJU A;  4XOG A;  1W20 A;  4HZZ A;  2W8B A;  1W8N A;  5F72 C;  4M4N A;  7NN9 A;  1W21 A;  3K38 A;  3H6J A;  1S1D A;  3DR2 A;  2W8B B;  3LI3 A;  4MZA A;  2FHR A;  1IVB A;  1XOG A;  1V3B A;  1N1T A;  4FJ6 A;  1RWL A;  4XJ8 A;  1V0F A;  2HTU A;  1MS3 A;  4GZX A;  2B8H A;  2QWF A;  2HU0 A;  2QWC A;  3TIB A;  2BAT A;  2P4O A;  2SIM A;  4XJR A;  4AHA A;  2F13 A;  5EO8 A;  4YZ2 A;  2HTV A;  4K3Y A;  2ISM A;  2ZZK A;  1INW A;  1Z4X A;  1DIM A;  1MS8 A;  2F12 A;  2FLU X;  1V0Z A;  2BF6 A;  4H52 A;  3D11 A;  1Q7F A;  2IAT A;  4FOQ A;  4FPK A;  4HIZ A;  1NNA A;  3CKZ A;  2Z32 A;  1V3D A;  4MC7 A;  5FZJ A;  1USR A;  4CPN A;  2ZB5 A;  4M4V A;  4K1K A;  4X6K A;  1QLG A;  4FPJ A;  1Z4V A;  4IYG A;  4DG6 A;  4FPE A;  3W09 A;  2W38 A;  4GZP A;  3B7E A;  4I00 A;  5FNS A;  1B9S A;  4MWL A;  4GZW A;  4MWX A;  4D4U A;  2XCY A;  5CGJ A;  1ING A;  1F8E A;  2QE8 A;  4IMB A;  1E1A A;  2AGS A;  3D12 A;  4O5S A;  4GZQ A;  4WEF A;  1C5K A;  1CRZ A;  4XJA A;  2QWD A;  1IUB A;  4B7Q A;  4ASC A;  2AEP A;  4KS4 A;  1B9T A;  3SOV A;  3INB A;  2HTQ A;  4KS2 A;  4JML A;  4J9T A;  2QWJ A;  3SAL A;  2GVW A;  2W5N A;  1ZI0 A;  2VAQ A;  5FNQ A;  3K37 A;  1INV A;  3U0S A;  4GB1 A;  1INH A;  4XJQ A;  4ZGC A;  2QWG A;  4MWU A;  1EUS A;  4MWY A;  3WDZ A;  2IVZ A;  3V65 B;  3II7 A;  4QN4 A;  4BBW A;  2IAW A;  3SLI A;  1MS1 A;  3L6V A;  4HHQ A;  1MS5 A;  1NCD N;  1NSC A;  1V2I A;  3T1E A;  2DYH A;  3LI5 A;  3TI8 A;  2ZW9 A;  3A72 A;  3GVL A;  1SUU A;  4IFL X;  4YZ5 A;  5HUK A;  3SOQ A;  3ADE A;  1INX A;  1V3C A;  2IAV A;  4FVK A;  3H73 A;  1N1V A;  1Z50 A;  5EO7 A;  1USX A;  3SRE A;  3CL2 A;  4FPL A;  2AEQ A;  2HU4 A;  3O4P A;  3E5Z A;  4YZ3 A;  5GX3 A;  2RKC A;  2FPB A;  4FPO B;  1Z4Z A;  4Q1U A;  1MZ6 A;  2IAR A;  4IN4 A;  3ALX A;  1S18 A;  2QWH A;  5EX7 A;  5B2D A;  1NCB N;  4FQ4 A;  1MS4 A;  3LI4 A;  3GVJ A;  4FPY A;  4WA5 A;  1N1S A;  5FNT A;  2W5O A;  5JYY A;  3KYA A;  2SLI A;  4CSD A;  1QBI A;  4GN7 A;  4XJ9 A;  2IAQ A;  4YW1 A;  3FW0 A;  2F29 A;  1S0J A;  3HLI A;  1F8B A;  2VK7 A;  1NCC N;  4ZLR A;  5D9B A;  2XZI A;  1SO7 A;  4B7M A;  2V91 A;  4B7J A;  3G4H A;  1WCQ A;  2VVZ A;  2BER A;  3HLH A;  4CPY A;  1NN2 A;  4QN7 A;  3FVZ A;  4Q6K A;  4HHO A;  4D8S A;  2YA4 A;  4YW5 A;  3B69 A;  2HT8 A;  4MZE A;  4UF7 A;  1NMB N;  1A4G A;  4D52 A;  2DG1 A;  2JKB A;  1H6L A;  2F0Z A;  2POO A;  4FOY A;  4GNA A;  4AH4 A;  4QN3 A;  1NSD A;  4FOW A;  4CHB A;  1IVD A;  3S8Z A;  4D52 B;  2YA8 A;  2VW1 A;  3TI6 A;  2F11 A;  3TIC A;  1IUC A;  1Z4W A;  2F27 A;  2FP8 A;  2F26 A;  4K1H A;  1N7D A;  4KS5 A;  4CPL A;  4WA3 A;  2F24 A;  2IAS A;  1U6D X;  2QWA A;  4XHX A;  4WA4 A;  2VSM A;  2F28 A;  4YZ4 A;  3UC1 A;  5NN9 A;  4NC5 A;  4MJV A;  2QWI A;  4M3M A;  3ALW A;  1N1Y A;  3CL0 A;  4MWW A;  1S0I A;  3SIL A;  4GDJ A;  1RWI A;  3K36 A;  4GEZ A;  4FPG A;  2QWB A;  4HZX A;  3SOB B;  3ZGD A;  4KS3 A;  2GVU A;  2HTY A;  3NSS A;  3WW9 A;  1VCU A;  3BYC A;  3HRP A;  4B7R A;  1C9U A;  3V64 C;  2ZWA A;  3H71 A;  4C1Y A;  2C4L A;  5D9D A;  4GN9 A;  2H2U A;  2XZK A;  3JU4 A;  1NMC A;  4DGR A;  4IFJ A;  4XIO A;  4YZ1 A;  1K32 A;  1X2R A;  4XJU A;  3VNH A;  4QNP A;  2G8S A;  2W20 A;  1NNC A;  5FZN A;  2ZB6 A;  4GN8 A;  4IFN X;  5FNU A;  1CRU A;  1L7G A;  3NN9 A;  2VK5 A;  5HUM A;  1E8T A;  3Q6P A;  2H2N A;  2XN4 A;  1INF A;  2WOZ A;  4MWR A;  4HZY A;  1SLL A;  2OJH A;  5GTQ A;  4CPM A;  2DG0 A;  2F25 A;  4L7D A;  2XZJ A;  5GX2 A;  4GZO A;  4FP3 A;  1CQ1 A;  2VW2 A;  4XIL A;  2SIL A;  3K3A A;  4KS1 A;  5GX1 A;  2HTW A;  2HT7 A;  4MWV A;  3S2K A;  1KIT A;  4CH9 A;  1INY A;  1IVF A;  1N6E A;  1V0E A;  1A4Q A;  3S94 A;  4PWZ A;  1V04 A;  2YDP A;  4GNB A;  4L7C A;  4GZT A;  1Z4Y A;  2VWD A;  2YDT A;  1F8C A;  4XMB A;  4YW4 A;  3V1S A;  4K1I A;  1XOE A;  3A9H A;  3VNG A;  4CPO A;  2FPC A;  2QWE A;  4IQK A;  5H47 A;  2A75 A;  2QWK A;  4X4A A;  1NMA N;  1V3E A;  3ZGC A;  2HTR A;  1NSB A;  1PJX A;  2IAX A;  1L7F A;  3S8V A;  4GNC A;  4MWJ A;  1MS0 A;  1X2J A;  3WN7 A;  4D52 C;  5HX0 A;  4FPH A;  3TI5 A;  1WCS A;  1L7H A;  2DSO A;  3G4E A;  3DAS A;  2VSK A;  4AGT A;  4FP2 A;  4NCS A;  3WWA A;  1W1X A;  1NNB A;  2IAU A;  3H72 A;  1W0P A;  1SLI A;  3GVK A;  1WP5 A;  4XHB A;  5HUN A;  1F8D A;  4HZV A;  4YW3 A;  5FNR A;  4NN9 A;  2IAO A;  2CML A;  4XJZ A;  5GX5 A;  3P5B L;  1A14 N;  1DIL A;  3O9K A;  3IAX A;  4XYX A;  3TC9 A;  4X49 A;  4FPC A;  5M1Z A;  1POO A;  4HW6 A;  1N6F A;  1N6D A;  1E8U A;  1OFZ A;  2C4A A;  3TIA A;  1EUT A;  4L7B A;  2F10 A;  4ZY3 A;  3SRG A;  4YY8 A;  3K39 A;  5B2C A;  1W8O A;  3KGG A;  1SNT A;  4K1J A;  1E8V A;  3Q6T A;  4UOU A;  4A0P A;  4JF7 A;  4R40 A;  4XJW A;  4H53 A;  5HUG A;  4QN5 A;  4XIK A;  4X47 A;  2YA5 A;  4N1B A;  4XMA A;  4GZS A;  3AMR A;  5GX4 A;  3A71 A;  1MS9 A;  3OPZ A;  1MR5 A;  3CYE A;  1IVE A;  4GDI A;  4O5T A;  1IVC A;  2GHS A;  3AMS A;  3NO0 A;  4G3N A;  4GJT A;  1BJI A;  3A9G A;  2HQS A;  2X9M A;  3SAN A;  3TI4 A;  2VK6 A;  4QN6 A;  4FZH A;  3TI3 A;  2IAP A;  2YA7 A;  2HT5 A;  1MZ5 A;  4SLI A;  1IVG A;  1EUR A;  2GVV A;  3O9J A;  4FOV A;  4FPF A;  1CVM A;  5F9T A;  3PJQ A;  4MX0 A;  1B9V A;  2AH2 A;  2FP9 A;  2VPJ A;  2VW0 A;  4WEG A;  4MWQ A;  4B7N A;  4AGI A;  4XMI A;  4YW2 A;  2YA6 A;  2GVX A;  2BZD A; 
#chains in the Genus database with same CATH homology
 1NCA N;  4CPZ A;  6NN9 A;  4XE9 A;  1W0O A;  1VCJ A;  4M4U A;  3BEQ A;  1EUU A;  1MWE A;  4HZW A;  4MJU A;  4XOG A;  1W20 A;  4HZZ A;  1W8N A;  4M4N A;  7NN9 A;  1W21 A;  3K38 A;  3H6J A;  1S1D A;  4MZA A;  2FHR A;  1IVB A;  1XOG A;  1V3B A;  1N1T A;  4FJ6 A;  4XJ8 A;  1V0F A;  2HTU A;  1MS3 A;  4GZX A;  2B8H A;  2QWF A;  2HU0 A;  2QWC A;  3TIB A;  2BAT A;  2SIM A;  4XJR A;  2F13 A;  4YZ2 A;  2HTV A;  4K3Y A;  1INW A;  1Z4X A;  1DIM A;  1MS8 A;  2F12 A;  1V0Z A;  2BF6 A;  4H52 A;  3D11 A;  4FOQ A;  4FPK A;  4HIZ A;  1NNA A;  3CKZ A;  1V3D A;  4MC7 A;  4CPN A;  1USR A;  2ZB5 A;  4M4V A;  4K1K A;  4X6K A;  4FPJ A;  1Z4V A;  4FPE A;  3W09 A;  2W38 A;  4GZP A;  3B7E A;  4I00 A;  1B9S A;  4MWL A;  4GZW A;  4MWX A;  2XCY A;  1ING A;  1F8E A;  2AGS A;  3D12 A;  4GZQ A;  4WEF A;  4XJA A;  2QWD A;  4B7Q A;  2AEP A;  4KS4 A;  1B9T A;  3INB A;  2HTQ A;  4KS2 A;  4J9T A;  2QWJ A;  3SAL A;  2W5N A;  3K37 A;  1INV A;  4GB1 A;  1INH A;  4XJQ A;  2QWG A;  4MWU A;  1EUS A;  4MWY A;  4QN4 A;  4BBW A;  3SLI A;  1MS1 A;  1MS5 A;  1V2I A;  1NCD N;  1NSC A;  3T1E A;  3TI8 A;  3A72 A;  3GVL A;  4YZ5 A;  5HUK A;  1INX A;  1V3C A;  4FVK A;  3H73 A;  1N1V A;  1Z50 A;  1USX A;  3CL2 A;  4FPL A;  2AEQ A;  2HU4 A;  4YZ3 A;  2RKC A;  4FPO B;  1Z4Z A;  1MZ6 A;  3ALX A;  1S18 A;  2QWH A;  5B2D A;  1NCB N;  4FQ4 A;  1MS4 A;  3GVJ A;  4FPY A;  4WA5 A;  1N1S A;  2W5O A;  5JYY A;  2SLI A;  4XJ9 A;  4YW1 A;  2F29 A;  1S0J A;  1F8B A;  2VK7 A;  1NCC N;  2XZI A;  1SO7 A;  4B7M A;  4B7J A;  1WCQ A;  2VVZ A;  2BER A;  4CPY A;  1NN2 A;  4QN7 A;  4Q6K A;  4D8S A;  2YA4 A;  4YW5 A;  3B69 A;  2HT8 A;  4MZE A;  4UF7 A;  1NMB N;  1A4G A;  2JKB A;  2F0Z A;  4FOY A;  4QN3 A;  1NSD A;  4FOW A;  1IVD A;  2YA8 A;  2VW1 A;  3TI6 A;  2F11 A;  3TIC A;  1Z4W A;  2F27 A;  2F26 A;  4K1H A;  4KS5 A;  4CPL A;  4WA3 A;  2F24 A;  2QWA A;  4XHX A;  4WA4 A;  2VSM A;  2F28 A;  4YZ4 A;  5NN9 A;  4NC5 A;  4MJV A;  2QWI A;  4M3M A;  3ALW A;  1N1Y A;  3CL0 A;  4MWW A;  1S0I A;  3SIL A;  4GDJ A;  4GEZ A;  3K36 A;  4FPG A;  2QWB A;  4HZX A;  4KS3 A;  2HTY A;  3NSS A;  1VCU A;  4B7R A;  3H71 A;  2C4L A;  2H2U A;  2XZK A;  3JU4 A;  1NMC A;  4DGR A;  4XIO A;  4YZ1 A;  4XJU A;  4QNP A;  2W20 A;  1NNC A;  2ZB6 A;  1L7G A;  3NN9 A;  2VK5 A;  5HUM A;  1E8T A;  2H2N A;  1INF A;  4MWR A;  4HZY A;  1SLL A;  4CPM A;  2F25 A;  2XZJ A;  4GZO A;  4FP3 A;  2VW2 A;  4XIL A;  2SIL A;  3K3A A;  4KS1 A;  2HTW A;  2HT7 A;  4MWV A;  1KIT A;  1INY A;  1IVF A;  1V0E A;  1A4Q A;  2YDP A;  4GZT A;  1Z4Y A;  2VWD A;  2YDT A;  1F8C A;  4YW4 A;  4K1I A;  1XOE A;  4CPO A;  2QWE A;  2A75 A;  2QWK A;  4X4A A;  1NMA N;  1V3E A;  2HTR A;  1NSB A;  1L7F A;  4MWJ A;  1MS0 A;  5HX0 A;  4FPH A;  3TI5 A;  1WCS A;  1L7H A;  2VSK A;  4FP2 A;  4NCS A;  1W1X A;  1NNB A;  3H72 A;  1W0P A;  1SLI A;  3GVK A;  4XHB A;  5HUN A;  1F8D A;  4HZV A;  4YW3 A;  4NN9 A;  2CML A;  4XJZ A;  1A14 N;  1DIL A;  3O9K A;  4XYX A;  4X49 A;  4FPC A;  5M1Z A;  1E8U A;  2C4A A;  3TIA A;  1EUT A;  2F10 A;  3K39 A;  5B2C A;  1W8O A;  1SNT A;  4K1J A;  1E8V A;  4JF7 A;  4XJW A;  4H53 A;  5HUG A;  4QN5 A;  4XIK A;  4X47 A;  2YA5 A;  4XMA A;  4GZS A;  3A71 A;  1MS9 A;  3OPZ A;  1MR5 A;  3CYE A;  1IVE A;  4GDI A;  1IVC A;  4GJT A;  1BJI A;  2X9M A;  3SAN A;  3TI4 A;  2VK6 A;  4QN6 A;  4FZH A;  3TI3 A;  2YA7 A;  2HT5 A;  1MZ5 A;  4SLI A;  1IVG A;  1EUR A;  3O9J A;  4FOV A;  4FPF A;  5F9T A;  3PJQ A;  4MX0 A;  1B9V A;  2AH2 A;  2VW0 A;  4WEG A;  4MWQ A;  4B7N A;  4XMI A;  4YW2 A;  2YA6 A;  2BZD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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