2F2FB

Crystal structure of cytolethal distending toxin (cdt) from actinobacillus actinomycetemcomitans
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
261
structure length
261
Chain Sequence
NLSDFKVATWNLQGSSAVNESKWNINVRQLLSGEQGADILMVQEAGSLPSSAVRTSRVIQHGGTPIEEYTWNLGTRSRPNMVYIYYSRLDVGANRVNLAIVSRRQADEAFIVHSDSSVLQSRPAVGIRIGTDVFFTVHALATGGSDAVSLIRNIFTTFTSSPSSPERRGYSWMVVGDFNRAPVNLEAALRQEPAVSENTIIIAPTEPTHRSGNILDYAILHDAHLPRREQARERIGASLMLNQLRSQITSDHFPVSFVHDR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Variation of loop sequence alters stability of cytolethal distending toxin (CDT): crystal structure of CDT from Actinobacillus actinomycetemcomitans
pubmed doi rcsb
molecule tags Toxin
source organism Aggregatibacter actinomycetemcomitans
molecule keywords Cytolethal distending toxin A
total genus 76
structure length 261
sequence length 261
chains with identical sequence E
ec nomenclature
pdb deposition date 2005-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2f2fB00
2JC4A 3NGNA 5J3ZA 1AKOA 4L1ZA 1HD7A 5DG0A 3NGOA 4B5JA 1DNKA 1WDUA 4GZ0A 4FPVA 2J63A 5DV2A 3W2YA 4RUWA 3G2CA 2A3ZB 3N9VA 4GEWA 4F1HA 5DFHA 3G3YA 1SI6X 4QHEA 3G00A 3NR8A 2V0SA 4C1RA 3I5VA 4AWNA 3I46A 2F1NA 3CJCD 3K55A 5A7IA 5INLA 5INMA 1BIXA 5INKA 2ISIA 3FZIA 3L1WA 4L1YA 5CFEA 2V0RA 1E9NA 4F1RA 3I41A 4JG3A 4IEMA 2D1KB 3W3DB 4F1IA 1SR4B 1Y21A 3G1KA 4GYZA 3MPRA 5EWTA 5J8NA 1I9YA 2IMQX 3DNIA 2A42B 4B5FA 4GZ1A 4B5HA 3I48A 5DV4A 2F2FB 2XSWA 1VYBA 3G2DA 5J3PA 2JC5A 2DDSA 5DFFA 4B5IA 1DE9A 5CFGA 5DFJA 3TEBA 5J3SA 4QHDA 1I9ZA 2EI9A 4L20A 3W2XA 3G0RA 3G91A 3NGQA 3G6SA 2A40B 5INOA 5INQA 3MTCA 5INNA 5J42A 2VOAA 3G0AA 1DEWA 1ATND 4GZ2A 4FVAA 4CMNA 1ZWXA 3GA6A 2A41B 1DE8A 4PUQA 2DNJA 4A9CA 4B5MA 2DDTA 2UYRX 4LNDA 1NTFA 3G8VA 4F1HB 3G4TA 5INPA 3G38A 4L21A 3U8UA 5HT2A 3WCXA 4CMLA 5DFIA 2O3HA 2DDRA 1YJHA 4B5GA 5A7JA 4QH9A 4K6LF 3G3CA 2O3CA
chains in the Genus database with same CATH superfamily
2JC4A 3NGNA 5J3ZA 1AKOA 4L1ZA 1HD7A 5DG0A 3NGOA 4B5JA 1DNKA 1WDUA 4GZ0A 4FPVA 2J63A 5DV2A 3W2YA 4RUWA 3G2CA 2A3ZB 3N9VA 4GEWA 4F1HA 5DFHA 3G3YA 1SI6X 4QHEA 3G00A 3NR8A 2V0SA 4C1RA 3I5VA 4AWNA 3I46A 2F1NA 3CJCD 3K55A 5A7IA 5INLA 5INMA 1BIXA 5INKA 2ISIA 3FZIA 3L1WA 4L1YA 5CFEA 2V0RA 1E9NA 4F1RA 3I41A 4JG3A 4IEMA 2D1KB 3W3DB 4F1IA 1SR4B 1Y21A 3G1KA 4GYZA 3MPRA 5EWTA 5J8NA 1I9YA 2IMQX 3DNIA 2A42B 4B5FA 4GZ1A 4B5HA 3I48A 5DV4A 2F2FB 2XSWA 1VYBA 3G2DA 5J3PA 2JC5A 2DDSA 5DFFA 4B5IA 1DE9A 5CFGA 5DFJA 3TEBA 5J3SA 4QHDA 1I9ZA 2EI9A 4L20A 3W2XA 3G0RA 3G91A 3NGQA 3G6SA 2A40B 5INOA 5INQA 3MTCA 5INNA 5J42A 2VOAA 3G0AA 1DEWA 1ATND 4GZ2A 4FVAA 4CMNA 1ZWXA 3GA6A 2A41B 1DE8A 4PUQA 2DNJA 4A9CA 4B5MA 2DDTA 2UYRX 4LNDA 1NTFA 3G8VA 4F1HB 3G4TA 5INPA 3G38A 4L21A 3U8UA 5HT2A 3WCXA 4CMLA 5DFIA 2O3HA 2DDRA 1YJHA 4B5GA 5A7JA 4QH9A 4K6LF 3G3CA 2O3CA
chains in the Genus database with same CATH topology
2JC4A 3NGNA 5J3ZA 1AKOA 4L1ZA 1HD7A 5DG0A 3NGOA 4B5JA 1DNKA 1WDUA 4GZ0A 4FPVA 2J63A 5DV2A 3W2YA 4RUWA 3G2CA 2A3ZB 3N9VA 4GEWA 4F1HA 5DFHA 3G3YA 1SI6X 4QHEA 3G00A 3NR8A 2V0SA 4C1RA 3I5VA 4AWNA 3I46A 2F1NA 3CJCD 3K55A 5A7IA 5INLA 5INMA 1BIXA 5INKA 2ISIA 3FZIA 3L1WA 4L1YA 5CFEA 2V0RA 1E9NA 4F1RA 3I41A 4JG3A 4IEMA 2D1KB 3W3DB 4F1IA 1SR4B 1Y21A 3G1KA 4GYZA 3MPRA 5EWTA 5J8NA 1I9YA 2IMQX 3DNIA 2A42B 4B5FA 4GZ1A 4B5HA 3I48A 5DV4A 2F2FB 2XSWA 1VYBA 3G2DA 5J3PA 2JC5A 2DDSA 5DFFA 4B5IA 1DE9A 5CFGA 5DFJA 3TEBA 5J3SA 4QHDA 1I9ZA 2EI9A 4L20A 3W2XA 3G0RA 3G91A 3NGQA 3G6SA 2A40B 5INOA 5INQA 3MTCA 5INNA 5J42A 2VOAA 3G0AA 1DEWA 1ATND 4GZ2A 4FVAA 4CMNA 1ZWXA 3GA6A 2A41B 1DE8A 4PUQA 2DNJA 4A9CA 4B5MA 2DDTA 2UYRX 4LNDA 1NTFA 3G8VA 4F1HB 3G4TA 5INPA 3G38A 4L21A 3U8UA 5HT2A 3WCXA 4CMLA 5DFIA 2O3HA 2DDRA 1YJHA 4B5GA 5A7JA 4QH9A 4K6LF 3G3CA 2O3CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JC4 A;  3NGN A;  5J3Z A;  1AKO A;  4L1Z A;  1HD7 A;  5DG0 A;  3NGO A;  4B5J A;  1DNK A;  1WDU A;  4GZ0 A;  4FPV A;  2J63 A;  5DV2 A;  3W2Y A;  4RUW A;  3G2C A;  2A3Z B;  3N9V A;  4GEW A;  4F1H A;  5DFH A;  3G3Y A;  1SI6 X;  4QHE A;  3G00 A;  3NR8 A;  2V0S A;  4C1R A;  3I5V A;  4AWN A;  3I46 A;  2F1N A;  3CJC D;  3K55 A;  5A7I A;  5INL A;  5INM A;  1BIX A;  5INK A;  2ISI A;  3FZI A;  3L1W A;  4L1Y A;  5CFE A;  2V0R A;  1E9N A;  4F1R A;  3I41 A;  4JG3 A;  4IEM A;  2D1K B;  3W3D B;  4F1I A;  1SR4 B;  1Y21 A;  3G1K A;  4GYZ A;  3MPR A;  5EWT A;  5J8N A;  1I9Y A;  2IMQ X;  3DNI A;  2A42 B;  4B5F A;  4GZ1 A;  4B5H A;  3I48 A;  5DV4 A;  2F2F B;  2XSW A;  1VYB A;  3G2D A;  5J3P A;  2JC5 A;  2DDS A;  5DFF A;  4B5I A;  1DE9 A;  5CFG A;  5DFJ A;  3TEB A;  5J3S A;  4QHD A;  1I9Z A;  2EI9 A;  4L20 A;  3W2X A;  3G0R A;  3G91 A;  3NGQ A;  3G6S A;  2A40 B;  5INO A;  5INQ A;  3MTC A;  5INN A;  5J42 A;  2VOA A;  3G0A A;  1DEW A;  1ATN D;  4GZ2 A;  4FVA A;  4CMN A;  1ZWX A;  3GA6 A;  2A41 B;  1DE8 A;  4PUQ A;  2DNJ A;  4A9C A;  4B5M A;  2DDT A;  2UYR X;  4LND A;  1NTF A;  3G8V A;  4F1H B;  3G4T A;  5INP A;  3G38 A;  4L21 A;  3U8U A;  5HT2 A;  3WCX A;  4CML A;  5DFI A;  2O3H A;  2DDR A;  1YJH A;  4B5G A;  5A7J A;  4QH9 A;  4K6L F;  3G3C A;  2O3C A; 
#chains in the Genus database with same CATH topology
 2JC4 A;  3NGN A;  5J3Z A;  1AKO A;  4L1Z A;  1HD7 A;  5DG0 A;  3NGO A;  4B5J A;  1DNK A;  1WDU A;  4GZ0 A;  4FPV A;  2J63 A;  5DV2 A;  3W2Y A;  4RUW A;  3G2C A;  2A3Z B;  3N9V A;  4GEW A;  4F1H A;  5DFH A;  3G3Y A;  1SI6 X;  4QHE A;  3G00 A;  3NR8 A;  2V0S A;  4C1R A;  3I5V A;  4AWN A;  3I46 A;  2F1N A;  3CJC D;  3K55 A;  5A7I A;  5INL A;  5INM A;  1BIX A;  5INK A;  2ISI A;  3FZI A;  3L1W A;  4L1Y A;  5CFE A;  2V0R A;  1E9N A;  4F1R A;  3I41 A;  4JG3 A;  4IEM A;  2D1K B;  3W3D B;  4F1I A;  1SR4 B;  1Y21 A;  3G1K A;  4GYZ A;  3MPR A;  5EWT A;  5J8N A;  1I9Y A;  2IMQ X;  3DNI A;  2A42 B;  4B5F A;  4GZ1 A;  4B5H A;  3I48 A;  5DV4 A;  2F2F B;  2XSW A;  1VYB A;  3G2D A;  5J3P A;  2JC5 A;  2DDS A;  5DFF A;  4B5I A;  1DE9 A;  5CFG A;  5DFJ A;  3TEB A;  5J3S A;  4QHD A;  1I9Z A;  2EI9 A;  4L20 A;  3W2X A;  3G0R A;  3G91 A;  3NGQ A;  3G6S A;  2A40 B;  5INO A;  5INQ A;  3MTC A;  5INN A;  5J42 A;  2VOA A;  3G0A A;  1DEW A;  1ATN D;  4GZ2 A;  4FVA A;  4CMN A;  1ZWX A;  3GA6 A;  2A41 B;  1DE8 A;  4PUQ A;  2DNJ A;  4A9C A;  4B5M A;  2DDT A;  2UYR X;  4LND A;  1NTF A;  3G8V A;  4F1H B;  3G4T A;  5INP A;  3G38 A;  4L21 A;  3U8U A;  5HT2 A;  3WCX A;  4CML A;  5DFI A;  2O3H A;  2DDR A;  1YJH A;  4B5G A;  5A7J A;  4QH9 A;  4K6L F;  3G3C A;  2O3C A; 
#chains in the Genus database with same CATH homology
 2JC4 A;  3NGN A;  5J3Z A;  1AKO A;  4L1Z A;  1HD7 A;  5DG0 A;  3NGO A;  4B5J A;  1DNK A;  1WDU A;  4GZ0 A;  4FPV A;  2J63 A;  5DV2 A;  3W2Y A;  4RUW A;  3G2C A;  2A3Z B;  3N9V A;  4GEW A;  4F1H A;  5DFH A;  3G3Y A;  1SI6 X;  4QHE A;  3G00 A;  3NR8 A;  2V0S A;  4C1R A;  3I5V A;  4AWN A;  3I46 A;  2F1N A;  3CJC D;  3K55 A;  5A7I A;  5INL A;  5INM A;  1BIX A;  5INK A;  2ISI A;  3FZI A;  3L1W A;  4L1Y A;  5CFE A;  2V0R A;  1E9N A;  4F1R A;  3I41 A;  4JG3 A;  4IEM A;  2D1K B;  3W3D B;  4F1I A;  1SR4 B;  1Y21 A;  3G1K A;  4GYZ A;  3MPR A;  5EWT A;  5J8N A;  1I9Y A;  2IMQ X;  3DNI A;  2A42 B;  4B5F A;  4GZ1 A;  4B5H A;  3I48 A;  5DV4 A;  2F2F B;  2XSW A;  1VYB A;  3G2D A;  5J3P A;  2JC5 A;  2DDS A;  5DFF A;  4B5I A;  1DE9 A;  5CFG A;  5DFJ A;  3TEB A;  5J3S A;  4QHD A;  1I9Z A;  2EI9 A;  4L20 A;  3W2X A;  3G0R A;  3G91 A;  3NGQ A;  3G6S A;  2A40 B;  5INO A;  5INQ A;  3MTC A;  5INN A;  5J42 A;  2VOA A;  3G0A A;  1DEW A;  1ATN D;  4GZ2 A;  4FVA A;  4CMN A;  1ZWX A;  3GA6 A;  2A41 B;  1DE8 A;  4PUQ A;  2DNJ A;  4A9C A;  4B5M A;  2DDT A;  2UYR X;  4LND A;  1NTF A;  3G8V A;  4F1H B;  3G4T A;  5INP A;  3G38 A;  4L21 A;  3U8U A;  5HT2 A;  3WCX A;  4CML A;  5DFI A;  2O3H A;  2DDR A;  1YJH A;  4B5G A;  5A7J A;  4QH9 A;  4K6L F;  3G3C A;  2O3C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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