2F8CF

Crystal structure of fpps in complex with zoledronate
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl Diphosphate Synthase
publication title Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 136
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2005-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2f8cF00
2F89F 3PKOA 4DZWA 3Q30A 3AQ0A 1YYTA 4KFAA 3SDQA 4P0XA 5B03A 5DJVF 4K10A 5IN8A 1HXGA 2Z7HA 2E8TA 2Z4VA 1JFAA 4XQSF 5CG6A 4MC0A 2E4OA 4NG6A 3N1WF 4N9UA 5CG5A 4DWBA 4E9ZA 5KSXF 4JXNA 3ACWA 1WL3A 4DI5A 3N5HF 3APZA 4LLSA 3S9VA 1UBXA 3WEKA 5IM1A 3CC9A 2PS8A 3P5PA 5EAUA 3EGTA 1JFGA 3LLWA 3LVSA 3VJAA 4HD1A 1N20A 2Z4ZA 5IK6A 5B0KA 3PYBA 1YHKA 3BNXA 3G4FA 3WSAA 3WCCA 1HXAA 3WCJA 1YYSA 3ZCDA 3KROA 2E8UA 2ZEUA 3KRFA 3UCAA 3CKEA 3QQVA 2OGDA 4LFEA 5DGNF 2FORA 5A0IA 2E92A 4PVYF 4JZBA 3KRCB 2PS5A 2Z52A 3P8LA 5DZ2A 3WC9A 3LK5A 2Z4YA 5ILHA 1UBYA 3TS7A 5ILYA 2Q58A 4KK2A 5H9DA 4DEMF 4F6XA 3OABB 1WL2A 1VG3A 4F62A 1YYUA 1VG4A 4KQUA 1PS1A 4XQTF 1N1BA 3DYHA 3Q2ZA 4OKMA 5AFXA 2ZCQA 1N23A 5DGMF 4EA1A 3DYFA 2F9KF 2RAHA 1RQIA 4KUXA 1UBWA 4RXDA 2Z4XA 3VJBA 3PYAA 3ACYA 3M9UA 1WL1A 4LUUA 3TFVA 3WJKA 1EZFA 3WE9A 5EROA 3M02A 2FTZA 2PS4A 3SDUA 3AE0A 4PVXF 4KWDA 1V4IA 1N21A 2OA6A 3ICMA 3PH7A 4LTZA 2E95A 4RXEA 3LEEA 5AYPA 4LZ0A 2O1OA 2AEKA 3M0GA 3TC1A 2Z50A 4FJQA 5JV0F 3RMGA 4KVDA 4F6VA 3Q1OA 3WCMA 3OYRA 3BNYA 3ZL6A 3LDWA 2ZCRA 4L2XF 5DHIA 5ILDA 5A0KA 4NFKF 3WCHA 2Q80A 3S4JA 5E8LA 1WL0A 4GP1A 1V4EA 2AZJA 4DWGA 5B0LA 5ILJA 2J1PA 3WCDA 3QKCA 4DHDA 5DW7A 3P8RA 3NF2A 3N3LF 4DXJA 3WJNA 3KBKA 2J1OA 2E8XA 1YYQA 3LGKA 4KPJA 1WKZA 3N1VF 2Q9YA 1KIZA 2E8VA 1VG2A 3LGZB 3NPKA 3Q2QA 3OACB 4MC8A 4P0VA 2DH4A 2OPMA 3G4DA 1V4JA 2E90A 3AQCB 3V1VA 1KIYA 4LTVA 1N22A 4KKMA 3SAEA 4EA2A 1YQ7A 4LZCA 3ADZA 3EZ3A 2E94A 3MAVA 2PS6A 3VJ8A 3SDVA 5B0IA 3WEGA 5B01A 4JXYA 2ZEVA 5DHKA 3KRAB 3KRPA 1YHLA 4KQSA 4LA6A 1RQJA 3WCFA 3P5RA 5IL3A 3PDEA 4LLTA 3VJCA 5B0JA 1WMWA 5E8HA 3N45F 3EFQA 3VJ9A 3ICKA 2F8ZF 3KRCA 3LSNA 3M01A 5DJRF 2E91A 3WCIA 3IPIA 5AELA 1V4HA 5C05A 3TFPA 1HM4A 2ZY1A 4KVYA 3WCAA 3N0FA 3CP6A 3WSBA 4NKFA 4LFVF 3LOMA 5EATA 3OABA 3ZMBA 4LIXA 3ASXA 4JYXA 5HN8A 4LA5A 2QISA 3RBMA 3ID0A 1YHMA 2AZLA 3LZ9A 2Q9ZA 5A0JA 4XQRF 3WCBA 5DJPF 4LPHF 5HN7A 2F7MF 4QXSF 4LZ3A 2ONGA 2AELA 2EWGA 4KVIA 5ERMA 3ZMCA 4KQ5A 3AQBB 1VG7A 4EA0A 4OGUA 3N6KF 2VF6A 4P0WA 5EASA 3N5JF 2Z4WA 2AZKA 5DGSF 1YJ4A 5IL8A 3KROB 4ZQ8A 4E1EA 3KRFB 3RYEA 4UMJA 1YV5A 4MC3A 1V4KA 3TFNA 3ICZA 3RYWA 2E8WA 4NUAA 5ILZA 5IMIA 3B7LA 3IBAA 2H8OA 4H5EF 5ILIA 4NFIF 1DI1A 4RYPA 3WJOA 1DGPA 2OPNA 1N24A 5B0MA 4GP2A 3WCLA 3WEJA 5E8KA 4OKZA 3LG5A 4H5DF 3ACXA 3N49F 4JZXA 1N1ZA 1ZW5A 3KRPB 2F94F 2ZCSA 5JV1F 1YYRA 2PS7A 3NRIA 4H5CF 5AHUB 5JV2F 3V1XA 2J5CA 3VJEA 4LXWA 2P1CA 3P41A 4FP4A 2E93A 3LJIA 1HM7A 5B02A 3WEHA 5I1UA 4KVWA 2ONHA 5HN9A 3MZVA 3WCEA 1UBVA 3WEIA 3W7FA 2ZCOA 3N46F 5JA0F 4LPGF 3V66A 4RXCA 5HNAA 5IVGA 4Q23A 3OACA 3M00A 5B00A 1FPSA 5IK9A 3ICNA 4LOBA 1HXCA 2I19A 2Z7IA 4QPFA 5DIQF 5IMPA 4OMGA 2F92F 5ER8A 5IKHA 2F8CF 1RTRA 4JVJF 3SDTA 5IKAA 4NFJF 1VG6A 4OMHA 3WEFA 5IMNA 3VJDA 3N3DA 1HX9A 4NKEA 5ILKA 4RXAA 5ERNA 3LMDA 3KRAA 3NPRA 5IK0A 1WY0A 2AETA 3WCGA 3KB9A 4GAXA 3SDRA 4N1ZF 4RNQA 2Z78A 4E9UA 3DYGA 4WK5A 3ZOUA 4LFGA 5JUZF 4GA3A 3N0GA 4KPDA
chains in the Genus database with same CATH superfamily
2F89F 3PKOA 4DZWA 3Q30A 3AQ0A 1YYTA 4KFAA 3SDQA 4P0XA 5B03A 5DJVF 4K10A 5IN8A 1HXGA 2Z7HA 2E8TA 2Z4VA 1JFAA 4XQSF 5CG6A 4MC0A 2E4OA 4NG6A 3N1WF 4N9UA 5CG5A 4DWBA 4E9ZA 5KSXF 4JXNA 3ACWA 1WL3A 4DI5A 3N5HF 3APZA 4LLSA 3S9VA 1UBXA 3WEKA 5IM1A 3CC9A 2PS8A 3P5PA 5EAUA 3EGTA 1JFGA 3LLWA 3LVSA 3VJAA 4HD1A 1N20A 2Z4ZA 5IK6A 5B0KA 3PYBA 1YHKA 3BNXA 3G4FA 3WSAA 3WCCA 1HXAA 3WCJA 1YYSA 3ZCDA 3KROA 2E8UA 2ZEUA 3KRFA 3UCAA 3CKEA 3QQVA 2OGDA 4LFEA 5DGNF 2FORA 5A0IA 2E92A 4PVYF 4JZBA 3KRCB 2PS5A 2Z52A 3P8LA 5DZ2A 3WC9A 3LK5A 2Z4YA 5ILHA 1UBYA 3TS7A 5ILYA 2Q58A 4KK2A 5H9DA 4DEMF 4F6XA 3OABB 1WL2A 1VG3A 4F62A 1YYUA 1VG4A 4KQUA 1PS1A 4XQTF 1N1BA 3DYHA 3Q2ZA 4OKMA 5AFXA 2ZCQA 1N23A 5DGMF 4EA1A 3DYFA 2F9KF 2RAHA 1RQIA 4KUXA 1UBWA 4RXDA 2Z4XA 3VJBA 3PYAA 3ACYA 3M9UA 1WL1A 4LUUA 3TFVA 3WJKA 1EZFA 3WE9A 5EROA 3M02A 2FTZA 2PS4A 3SDUA 3AE0A 4PVXF 4KWDA 1V4IA 1N21A 2OA6A 3ICMA 3PH7A 4LTZA 2E95A 4RXEA 3LEEA 5AYPA 4LZ0A 2O1OA 2AEKA 3M0GA 3TC1A 2Z50A 4FJQA 5JV0F 3RMGA 4KVDA 4F6VA 3Q1OA 3WCMA 3OYRA 3BNYA 3ZL6A 3LDWA 2ZCRA 4L2XF 5DHIA 5ILDA 5A0KA 4NFKF 3WCHA 2Q80A 3S4JA 5E8LA 1WL0A 4GP1A 1V4EA 2AZJA 4DWGA 5B0LA 5ILJA 2J1PA 3WCDA 3QKCA 4DHDA 5DW7A 3P8RA 3NF2A 3N3LF 4DXJA 3WJNA 3KBKA 2J1OA 2E8XA 1YYQA 3LGKA 4KPJA 1WKZA 3N1VF 2Q9YA 1KIZA 2E8VA 1VG2A 3LGZB 3NPKA 3Q2QA 3OACB 4MC8A 4P0VA 2DH4A 2OPMA 3G4DA 1V4JA 2E90A 3AQCB 3V1VA 1KIYA 4LTVA 1N22A 4KKMA 3SAEA 4EA2A 1YQ7A 4LZCA 3ADZA 3EZ3A 2E94A 3MAVA 2PS6A 3VJ8A 3SDVA 5B0IA 3WEGA 5B01A 4JXYA 2ZEVA 5DHKA 3KRAB 3KRPA 1YHLA 4KQSA 4LA6A 1RQJA 3WCFA 3P5RA 5IL3A 3PDEA 4LLTA 3VJCA 5B0JA 1WMWA 5E8HA 3N45F 3EFQA 3VJ9A 3ICKA 2F8ZF 3KRCA 3LSNA 3M01A 5DJRF 2E91A 3WCIA 3IPIA 5AELA 1V4HA 5C05A 3TFPA 1HM4A 2ZY1A 4KVYA 3WCAA 3N0FA 3CP6A 3WSBA 4NKFA 4LFVF 3LOMA 5EATA 3OABA 3ZMBA 4LIXA 3ASXA 4JYXA 5HN8A 4LA5A 2QISA 3RBMA 3ID0A 1YHMA 2AZLA 3LZ9A 2Q9ZA 5A0JA 4XQRF 3WCBA 5DJPF 4LPHF 5HN7A 2F7MF 4QXSF 4LZ3A 2ONGA 2AELA 2EWGA 4KVIA 5ERMA 3ZMCA 4KQ5A 3AQBB 1VG7A 4EA0A 4OGUA 3N6KF 2VF6A 4P0WA 5EASA 3N5JF 2Z4WA 2AZKA 5DGSF 1YJ4A 5IL8A 3KROB 4ZQ8A 4E1EA 3KRFB 3RYEA 4UMJA 1YV5A 4MC3A 1V4KA 3TFNA 3ICZA 3RYWA 2E8WA 4NUAA 5ILZA 5IMIA 3B7LA 3IBAA 2H8OA 4H5EF 5ILIA 4NFIF 1DI1A 4RYPA 3WJOA 1DGPA 2OPNA 1N24A 5B0MA 4GP2A 3WCLA 3WEJA 5E8KA 4OKZA 3LG5A 4H5DF 3ACXA 3N49F 4JZXA 1N1ZA 1ZW5A 3KRPB 2F94F 2ZCSA 5JV1F 1YYRA 2PS7A 3NRIA 4H5CF 5AHUB 5JV2F 3V1XA 2J5CA 3VJEA 4LXWA 2P1CA 3P41A 4FP4A 2E93A 3LJIA 1HM7A 5B02A 3WEHA 5I1UA 4KVWA 2ONHA 5HN9A 3MZVA 3WCEA 1UBVA 3WEIA 3W7FA 2ZCOA 3N46F 5JA0F 4LPGF 3V66A 4RXCA 5HNAA 5IVGA 4Q23A 3OACA 3M00A 5B00A 1FPSA 5IK9A 3ICNA 4LOBA 1HXCA 2I19A 2Z7IA 4QPFA 5DIQF 5IMPA 4OMGA 2F92F 5ER8A 5IKHA 2F8CF 1RTRA 4JVJF 3SDTA 5IKAA 4NFJF 1VG6A 4OMHA 3WEFA 5IMNA 3VJDA 3N3DA 1HX9A 4NKEA 5ILKA 4RXAA 5ERNA 3LMDA 3KRAA 3NPRA 5IK0A 1WY0A 2AETA 3WCGA 3KB9A 4GAXA 3SDRA 4N1ZF 4RNQA 2Z78A 4E9UA 3DYGA 4WK5A 3ZOUA 4LFGA 5JUZF 4GA3A 3N0GA 4KPDA
chains in the Genus database with same CATH topology
2F89F 3PKOA 4DZWA 3Q30A 3AQ0A 1YYTA 4KFAA 3SDQA 4P0XA 5B03A 5DJVF 4K10A 5IN8A 1HXGA 2Z7HA 2E8TA 2Z4VA 1JFAA 4XQSF 5CG6A 4MC0A 2E4OA 4NG6A 3N1WF 4N9UA 5CG5A 4DWBA 4E9ZA 5KSXF 4JXNA 3ACWA 1WL3A 4DI5A 3N5HF 3APZA 4LLSA 3S9VA 1UBXA 3WEKA 5IM1A 3CC9A 2PS8A 3P5PA 5EAUA 3EGTA 1JFGA 3LLWA 3LVSA 3VJAA 4HD1A 1N20A 2Z4ZA 5IK6A 5B0KA 3PYBA 1YHKA 3BNXA 3G4FA 3WSAA 3WCCA 1HXAA 3WCJA 1YYSA 3ZCDA 3KROA 2E8UA 2ZEUA 3KRFA 3UCAA 3CKEA 3QQVA 2OGDA 4LFEA 5DGNF 2FORA 5A0IA 2E92A 4PVYF 4JZBA 3KRCB 2PS5A 2Z52A 3P8LA 5DZ2A 3WC9A 3LK5A 2Z4YA 5ILHA 1UBYA 3TS7A 5ILYA 2Q58A 4KK2A 5H9DA 4DEMF 4F6XA 3OABB 1WL2A 1VG3A 4F62A 1YYUA 1VG4A 4KQUA 1PS1A 4XQTF 1N1BA 3DYHA 3Q2ZA 4OKMA 5AFXA 2ZCQA 1N23A 5DGMF 4EA1A 3DYFA 2F9KF 2RAHA 1RQIA 4KUXA 1UBWA 4RXDA 2Z4XA 3VJBA 3PYAA 3ACYA 3M9UA 1WL1A 4LUUA 3TFVA 3WJKA 1EZFA 3WE9A 5EROA 3M02A 2FTZA 2PS4A 3SDUA 3AE0A 4PVXF 4KWDA 1V4IA 1N21A 2OA6A 3ICMA 3PH7A 4LTZA 2E95A 4RXEA 3LEEA 5AYPA 4LZ0A 2O1OA 2AEKA 3M0GA 3TC1A 2Z50A 4FJQA 5JV0F 3RMGA 4KVDA 4F6VA 3Q1OA 3WCMA 3OYRA 3BNYA 3ZL6A 3LDWA 2ZCRA 4L2XF 5DHIA 5ILDA 5A0KA 4NFKF 3WCHA 2Q80A 3S4JA 5E8LA 1WL0A 4GP1A 1V4EA 2AZJA 4DWGA 5B0LA 5ILJA 2J1PA 3WCDA 3QKCA 4DHDA 5DW7A 3P8RA 3NF2A 3N3LF 4DXJA 3WJNA 3KBKA 2J1OA 2E8XA 1YYQA 3LGKA 4KPJA 1WKZA 3N1VF 2Q9YA 1KIZA 2E8VA 1VG2A 3LGZB 3NPKA 3Q2QA 3OACB 4MC8A 4P0VA 2DH4A 2OPMA 3G4DA 1V4JA 2E90A 3AQCB 3V1VA 1KIYA 4LTVA 1N22A 4KKMA 3SAEA 4EA2A 1YQ7A 4LZCA 3ADZA 3EZ3A 2E94A 3MAVA 2PS6A 3VJ8A 3SDVA 5B0IA 3WEGA 5B01A 4JXYA 2ZEVA 5DHKA 3KRAB 3KRPA 1YHLA 4KQSA 4LA6A 1RQJA 3WCFA 3P5RA 5IL3A 3PDEA 4LLTA 3VJCA 5B0JA 1WMWA 5E8HA 3N45F 3EFQA 3VJ9A 3ICKA 2F8ZF 3KRCA 3LSNA 3M01A 5DJRF 2E91A 3WCIA 3IPIA 5AELA 1V4HA 5C05A 3TFPA 1HM4A 2ZY1A 4KVYA 3WCAA 3N0FA 3CP6A 3WSBA 4NKFA 4LFVF 3LOMA 5EATA 3OABA 3ZMBA 4LIXA 3ASXA 4JYXA 5HN8A 4LA5A 2QISA 3RBMA 3ID0A 1YHMA 2AZLA 3LZ9A 2Q9ZA 5A0JA 4XQRF 3WCBA 5DJPF 4LPHF 5HN7A 2F7MF 4QXSF 4LZ3A 2ONGA 2AELA 2EWGA 4KVIA 5ERMA 3ZMCA 4KQ5A 3AQBB 1VG7A 4EA0A 4OGUA 3N6KF 2VF6A 4P0WA 5EASA 3N5JF 2Z4WA 2AZKA 5DGSF 1YJ4A 5IL8A 3KROB 4ZQ8A 4E1EA 3KRFB 3RYEA 4UMJA 1YV5A 4MC3A 1V4KA 3TFNA 3ICZA 3RYWA 2E8WA 4NUAA 5ILZA 5IMIA 3B7LA 3IBAA 2H8OA 4H5EF 5ILIA 4NFIF 1DI1A 4RYPA 3WJOA 1DGPA 2OPNA 1N24A 5B0MA 4GP2A 3WCLA 3WEJA 5E8KA 4OKZA 3LG5A 4H5DF 3ACXA 3N49F 4JZXA 1N1ZA 1ZW5A 3KRPB 2F94F 2ZCSA 5JV1F 1YYRA 2PS7A 3NRIA 4H5CF 5AHUB 5JV2F 3V1XA 2J5CA 3VJEA 4LXWA 2P1CA 3P41A 4FP4A 2E93A 3LJIA 1HM7A 5B02A 3WEHA 5I1UA 4KVWA 2ONHA 5HN9A 3MZVA 3WCEA 1UBVA 3WEIA 3W7FA 2ZCOA 3N46F 5JA0F 4LPGF 3V66A 4RXCA 5HNAA 5IVGA 4Q23A 3OACA 3M00A 5B00A 1FPSA 5IK9A 3ICNA 4LOBA 1HXCA 2I19A 2Z7IA 4QPFA 5DIQF 5IMPA 4OMGA 2F92F 5ER8A 5IKHA 2F8CF 1RTRA 4JVJF 3SDTA 5IKAA 4NFJF 1VG6A 4OMHA 3WEFA 5IMNA 3VJDA 3N3DA 1HX9A 4NKEA 5ILKA 4RXAA 5ERNA 3LMDA 3KRAA 3NPRA 5IK0A 1WY0A 2AETA 3WCGA 3KB9A 4GAXA 3SDRA 4N1ZF 4RNQA 2Z78A 4E9UA 3DYGA 4WK5A 3ZOUA 4LFGA 5JUZF 4GA3A 3N0GA 4KPDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F89 F;  3PKO A;  4DZW A;  3Q30 A;  3AQ0 A;  1YYT A;  4KFA A;  3SDQ A;  4P0X A;  5B03 A;  5DJV F;  4K10 A;  5IN8 A;  1HXG A;  2Z7H A;  2E8T A;  2Z4V A;  1JFA A;  4XQS F;  5CG6 A;  4MC0 A;  2E4O A;  4NG6 A;  3N1W F;  4N9U A;  5CG5 A;  4DWB A;  4E9Z A;  5KSX F;  4JXN A;  3ACW A;  1WL3 A;  4DI5 A;  3N5H F;  3APZ A;  4LLS A;  3S9V A;  1UBX A;  3WEK A;  5IM1 A;  3CC9 A;  2PS8 A;  3P5P A;  5EAU A;  3EGT A;  1JFG A;  3LLW A;  3LVS A;  3VJA A;  4HD1 A;  1N20 A;  2Z4Z A;  5IK6 A;  5B0K A;  3PYB A;  1YHK A;  3BNX A;  3G4F A;  3WSA A;  3WCC A;  1HXA A;  3WCJ A;  1YYS A;  3ZCD A;  3KRO A;  2E8U A;  2ZEU A;  3KRF A;  3UCA A;  3CKE A;  3QQV A;  2OGD A;  4LFE A;  5DGN F;  2FOR A;  5A0I A;  2E92 A;  4PVY F;  4JZB A;  3KRC B;  2PS5 A;  2Z52 A;  3P8L A;  5DZ2 A;  3WC9 A;  3LK5 A;  2Z4Y A;  5ILH A;  1UBY A;  3TS7 A;  5ILY A;  2Q58 A;  4KK2 A;  5H9D A;  4DEM F;  4F6X A;  3OAB B;  1WL2 A;  1VG3 A;  4F62 A;  1YYU A;  1VG4 A;  4KQU A;  1PS1 A;  4XQT F;  1N1B A;  3DYH A;  3Q2Z A;  4OKM A;  5AFX A;  2ZCQ A;  1N23 A;  5DGM F;  4EA1 A;  3DYF A;  2F9K F;  2RAH A;  1RQI A;  4KUX A;  1UBW A;  4RXD A;  2Z4X A;  3VJB A;  3PYA A;  3ACY A;  3M9U A;  1WL1 A;  4LUU A;  3TFV A;  3WJK A;  1EZF A;  3WE9 A;  5ERO A;  3M02 A;  2FTZ A;  2PS4 A;  3SDU A;  3AE0 A;  4PVX F;  4KWD A;  1V4I A;  1N21 A;  2OA6 A;  3ICM A;  3PH7 A;  4LTZ A;  2E95 A;  4RXE A;  3LEE A;  5AYP A;  4LZ0 A;  2O1O A;  2AEK A;  3M0G A;  3TC1 A;  2Z50 A;  4FJQ A;  5JV0 F;  3RMG A;  4KVD A;  4F6V A;  3Q1O A;  3WCM A;  3OYR A;  3BNY A;  3ZL6 A;  3LDW A;  2ZCR A;  4L2X F;  5DHI A;  5ILD A;  5A0K A;  4NFK F;  3WCH A;  2Q80 A;  3S4J A;  5E8L A;  1WL0 A;  4GP1 A;  1V4E A;  2AZJ A;  4DWG A;  5B0L A;  5ILJ A;  2J1P A;  3WCD A;  3QKC A;  4DHD A;  5DW7 A;  3P8R A;  3NF2 A;  3N3L F;  4DXJ A;  3WJN A;  3KBK A;  2J1O A;  2E8X A;  1YYQ A;  3LGK A;  4KPJ A;  1WKZ A;  3N1V F;  2Q9Y A;  1KIZ A;  2E8V A;  1VG2 A;  3LGZ B;  3NPK A;  3Q2Q A;  3OAC B;  4MC8 A;  4P0V A;  2DH4 A;  2OPM A;  3G4D A;  1V4J A;  2E90 A;  3AQC B;  3V1V A;  1KIY A;  4LTV A;  1N22 A;  4KKM A;  3SAE A;  4EA2 A;  1YQ7 A;  4LZC A;  3ADZ A;  3EZ3 A;  2E94 A;  3MAV A;  2PS6 A;  3VJ8 A;  3SDV A;  5B0I A;  3WEG A;  5B01 A;  4JXY A;  2ZEV A;  5DHK A;  3KRA B;  3KRP A;  1YHL A;  4KQS A;  4LA6 A;  1RQJ A;  3WCF A;  3P5R A;  5IL3 A;  3PDE A;  4LLT A;  3VJC A;  5B0J A;  1WMW A;  5E8H A;  3N45 F;  3EFQ A;  3VJ9 A;  3ICK A;  2F8Z F;  3KRC A;  3LSN A;  3M01 A;  5DJR F;  2E91 A;  3WCI A;  3IPI A;  5AEL A;  1V4H A;  5C05 A;  3TFP A;  1HM4 A;  2ZY1 A;  4KVY A;  3WCA A;  3N0F A;  3CP6 A;  3WSB A;  4NKF A;  4LFV F;  3LOM A;  5EAT A;  3OAB A;  3ZMB A;  4LIX A;  3ASX A;  4JYX A;  5HN8 A;  4LA5 A;  2QIS A;  3RBM A;  3ID0 A;  1YHM A;  2AZL A;  3LZ9 A;  2Q9Z A;  5A0J A;  4XQR F;  3WCB A;  5DJP F;  4LPH F;  5HN7 A;  2F7M F;  4QXS F;  4LZ3 A;  2ONG A;  2AEL A;  2EWG A;  4KVI A;  5ERM A;  3ZMC A;  4KQ5 A;  3AQB B;  1VG7 A;  4EA0 A;  4OGU A;  3N6K F;  2VF6 A;  4P0W A;  5EAS A;  3N5J F;  2Z4W A;  2AZK A;  5DGS F;  1YJ4 A;  5IL8 A;  3KRO B;  4ZQ8 A;  4E1E A;  3KRF B;  3RYE A;  4UMJ A;  1YV5 A;  4MC3 A;  1V4K A;  3TFN A;  3ICZ A;  3RYW A;  2E8W A;  4NUA A;  5ILZ A;  5IMI A;  3B7L A;  3IBA A;  2H8O A;  4H5E F;  5ILI A;  4NFI F;  1DI1 A;  4RYP A;  3WJO A;  1DGP A;  2OPN A;  1N24 A;  5B0M A;  4GP2 A;  3WCL A;  3WEJ A;  5E8K A;  4OKZ A;  3LG5 A;  4H5D F;  3ACX A;  3N49 F;  4JZX A;  1N1Z A;  1ZW5 A;  3KRP B;  2F94 F;  2ZCS A;  5JV1 F;  1YYR A;  2PS7 A;  3NRI A;  4H5C F;  5AHU B;  5JV2 F;  3V1X A;  2J5C A;  3VJE A;  4LXW A;  2P1C A;  3P41 A;  4FP4 A;  2E93 A;  3LJI A;  1HM7 A;  5B02 A;  3WEH A;  5I1U A;  4KVW A;  2ONH A;  5HN9 A;  3MZV A;  3WCE A;  1UBV A;  3WEI A;  3W7F A;  2ZCO A;  3N46 F;  5JA0 F;  4LPG F;  3V66 A;  4RXC A;  5HNA A;  5IVG A;  4Q23 A;  3OAC A;  3M00 A;  5B00 A;  1FPS A;  5IK9 A;  3ICN A;  4LOB A;  1HXC A;  2I19 A;  2Z7I A;  4QPF A;  5DIQ F;  5IMP A;  4OMG A;  2F92 F;  5ER8 A;  5IKH A;  2F8C F;  1RTR A;  4JVJ F;  3SDT A;  5IKA A;  4NFJ F;  1VG6 A;  4OMH A;  3WEF A;  5IMN A;  3VJD A;  3N3D A;  1HX9 A;  4NKE A;  5ILK A;  4RXA A;  5ERN A;  3LMD A;  3KRA A;  3NPR A;  5IK0 A;  1WY0 A;  2AET A;  3WCG A;  3KB9 A;  4GAX A;  3SDR A;  4N1Z F;  4RNQ A;  2Z78 A;  4E9U A;  3DYG A;  4WK5 A;  3ZOU A;  4LFG A;  5JUZ F;  4GA3 A;  3N0G A;  4KPD A; 
#chains in the Genus database with same CATH topology
 2F89 F;  3PKO A;  4DZW A;  3Q30 A;  3AQ0 A;  1YYT A;  4KFA A;  3SDQ A;  4P0X A;  5B03 A;  5DJV F;  4K10 A;  5IN8 A;  1HXG A;  2Z7H A;  2E8T A;  2Z4V A;  1JFA A;  4XQS F;  5CG6 A;  4MC0 A;  2E4O A;  4NG6 A;  3N1W F;  4N9U A;  5CG5 A;  4DWB A;  4E9Z A;  5KSX F;  4JXN A;  3ACW A;  1WL3 A;  4DI5 A;  3N5H F;  3APZ A;  4LLS A;  3S9V A;  1UBX A;  3WEK A;  5IM1 A;  3CC9 A;  2PS8 A;  3P5P A;  5EAU A;  3EGT A;  1JFG A;  3LLW A;  3LVS A;  3VJA A;  4HD1 A;  1N20 A;  2Z4Z A;  5IK6 A;  5B0K A;  3PYB A;  1YHK A;  3BNX A;  3G4F A;  3WSA A;  3WCC A;  1HXA A;  3WCJ A;  1YYS A;  3ZCD A;  3KRO A;  2E8U A;  2ZEU A;  3KRF A;  3UCA A;  3CKE A;  3QQV A;  2OGD A;  4LFE A;  5DGN F;  2FOR A;  5A0I A;  2E92 A;  4PVY F;  4JZB A;  3KRC B;  2PS5 A;  2Z52 A;  3P8L A;  5DZ2 A;  3WC9 A;  3LK5 A;  2Z4Y A;  5ILH A;  1UBY A;  3TS7 A;  5ILY A;  2Q58 A;  4KK2 A;  5H9D A;  4DEM F;  4F6X A;  3OAB B;  1WL2 A;  1VG3 A;  4F62 A;  1YYU A;  1VG4 A;  4KQU A;  1PS1 A;  4XQT F;  1N1B A;  3DYH A;  3Q2Z A;  4OKM A;  5AFX A;  2ZCQ A;  1N23 A;  5DGM F;  4EA1 A;  3DYF A;  2F9K F;  2RAH A;  1RQI A;  4KUX A;  1UBW A;  4RXD A;  2Z4X A;  3VJB A;  3PYA A;  3ACY A;  3M9U A;  1WL1 A;  4LUU A;  3TFV A;  3WJK A;  1EZF A;  3WE9 A;  5ERO A;  3M02 A;  2FTZ A;  2PS4 A;  3SDU A;  3AE0 A;  4PVX F;  4KWD A;  1V4I A;  1N21 A;  2OA6 A;  3ICM A;  3PH7 A;  4LTZ A;  2E95 A;  4RXE A;  3LEE A;  5AYP A;  4LZ0 A;  2O1O A;  2AEK A;  3M0G A;  3TC1 A;  2Z50 A;  4FJQ A;  5JV0 F;  3RMG A;  4KVD A;  4F6V A;  3Q1O A;  3WCM A;  3OYR A;  3BNY A;  3ZL6 A;  3LDW A;  2ZCR A;  4L2X F;  5DHI A;  5ILD A;  5A0K A;  4NFK F;  3WCH A;  2Q80 A;  3S4J A;  5E8L A;  1WL0 A;  4GP1 A;  1V4E A;  2AZJ A;  4DWG A;  5B0L A;  5ILJ A;  2J1P A;  3WCD A;  3QKC A;  4DHD A;  5DW7 A;  3P8R A;  3NF2 A;  3N3L F;  4DXJ A;  3WJN A;  3KBK A;  2J1O A;  2E8X A;  1YYQ A;  3LGK A;  4KPJ A;  1WKZ A;  3N1V F;  2Q9Y A;  1KIZ A;  2E8V A;  1VG2 A;  3LGZ B;  3NPK A;  3Q2Q A;  3OAC B;  4MC8 A;  4P0V A;  2DH4 A;  2OPM A;  3G4D A;  1V4J A;  2E90 A;  3AQC B;  3V1V A;  1KIY A;  4LTV A;  1N22 A;  4KKM A;  3SAE A;  4EA2 A;  1YQ7 A;  4LZC A;  3ADZ A;  3EZ3 A;  2E94 A;  3MAV A;  2PS6 A;  3VJ8 A;  3SDV A;  5B0I A;  3WEG A;  5B01 A;  4JXY A;  2ZEV A;  5DHK A;  3KRA B;  3KRP A;  1YHL A;  4KQS A;  4LA6 A;  1RQJ A;  3WCF A;  3P5R A;  5IL3 A;  3PDE A;  4LLT A;  3VJC A;  5B0J A;  1WMW A;  5E8H A;  3N45 F;  3EFQ A;  3VJ9 A;  3ICK A;  2F8Z F;  3KRC A;  3LSN A;  3M01 A;  5DJR F;  2E91 A;  3WCI A;  3IPI A;  5AEL A;  1V4H A;  5C05 A;  3TFP A;  1HM4 A;  2ZY1 A;  4KVY A;  3WCA A;  3N0F A;  3CP6 A;  3WSB A;  4NKF A;  4LFV F;  3LOM A;  5EAT A;  3OAB A;  3ZMB A;  4LIX A;  3ASX A;  4JYX A;  5HN8 A;  4LA5 A;  2QIS A;  3RBM A;  3ID0 A;  1YHM A;  2AZL A;  3LZ9 A;  2Q9Z A;  5A0J A;  4XQR F;  3WCB A;  5DJP F;  4LPH F;  5HN7 A;  2F7M F;  4QXS F;  4LZ3 A;  2ONG A;  2AEL A;  2EWG A;  4KVI A;  5ERM A;  3ZMC A;  4KQ5 A;  3AQB B;  1VG7 A;  4EA0 A;  4OGU A;  3N6K F;  2VF6 A;  4P0W A;  5EAS A;  3N5J F;  2Z4W A;  2AZK A;  5DGS F;  1YJ4 A;  5IL8 A;  3KRO B;  4ZQ8 A;  4E1E A;  3KRF B;  3RYE A;  4UMJ A;  1YV5 A;  4MC3 A;  1V4K A;  3TFN A;  3ICZ A;  3RYW A;  2E8W A;  4NUA A;  5ILZ A;  5IMI A;  3B7L A;  3IBA A;  2H8O A;  4H5E F;  5ILI A;  4NFI F;  1DI1 A;  4RYP A;  3WJO A;  1DGP A;  2OPN A;  1N24 A;  5B0M A;  4GP2 A;  3WCL A;  3WEJ A;  5E8K A;  4OKZ A;  3LG5 A;  4H5D F;  3ACX A;  3N49 F;  4JZX A;  1N1Z A;  1ZW5 A;  3KRP B;  2F94 F;  2ZCS A;  5JV1 F;  1YYR A;  2PS7 A;  3NRI A;  4H5C F;  5AHU B;  5JV2 F;  3V1X A;  2J5C A;  3VJE A;  4LXW A;  2P1C A;  3P41 A;  4FP4 A;  2E93 A;  3LJI A;  1HM7 A;  5B02 A;  3WEH A;  5I1U A;  4KVW A;  2ONH A;  5HN9 A;  3MZV A;  3WCE A;  1UBV A;  3WEI A;  3W7F A;  2ZCO A;  3N46 F;  5JA0 F;  4LPG F;  3V66 A;  4RXC A;  5HNA A;  5IVG A;  4Q23 A;  3OAC A;  3M00 A;  5B00 A;  1FPS A;  5IK9 A;  3ICN A;  4LOB A;  1HXC A;  2I19 A;  2Z7I A;  4QPF A;  5DIQ F;  5IMP A;  4OMG A;  2F92 F;  5ER8 A;  5IKH A;  2F8C F;  1RTR A;  4JVJ F;  3SDT A;  5IKA A;  4NFJ F;  1VG6 A;  4OMH A;  3WEF A;  5IMN A;  3VJD A;  3N3D A;  1HX9 A;  4NKE A;  5ILK A;  4RXA A;  5ERN A;  3LMD A;  3KRA A;  3NPR A;  5IK0 A;  1WY0 A;  2AET A;  3WCG A;  3KB9 A;  4GAX A;  3SDR A;  4N1Z F;  4RNQ A;  2Z78 A;  4E9U A;  3DYG A;  4WK5 A;  3ZOU A;  4LFG A;  5JUZ F;  4GA3 A;  3N0G A;  4KPD A; 
#chains in the Genus database with same CATH homology
 2F89 F;  3PKO A;  4DZW A;  3Q30 A;  3AQ0 A;  1YYT A;  4KFA A;  3SDQ A;  4P0X A;  5B03 A;  5DJV F;  4K10 A;  5IN8 A;  1HXG A;  2Z7H A;  2E8T A;  2Z4V A;  1JFA A;  4XQS F;  5CG6 A;  4MC0 A;  2E4O A;  4NG6 A;  3N1W F;  4N9U A;  5CG5 A;  4DWB A;  4E9Z A;  5KSX F;  4JXN A;  3ACW A;  1WL3 A;  4DI5 A;  3N5H F;  3APZ A;  4LLS A;  3S9V A;  1UBX A;  3WEK A;  5IM1 A;  3CC9 A;  2PS8 A;  3P5P A;  5EAU A;  3EGT A;  1JFG A;  3LLW A;  3LVS A;  3VJA A;  4HD1 A;  1N20 A;  2Z4Z A;  5IK6 A;  5B0K A;  3PYB A;  1YHK A;  3BNX A;  3G4F A;  3WSA A;  3WCC A;  1HXA A;  3WCJ A;  1YYS A;  3ZCD A;  3KRO A;  2E8U A;  2ZEU A;  3KRF A;  3UCA A;  3CKE A;  3QQV A;  2OGD A;  4LFE A;  5DGN F;  2FOR A;  5A0I A;  2E92 A;  4PVY F;  4JZB A;  3KRC B;  2PS5 A;  2Z52 A;  3P8L A;  5DZ2 A;  3WC9 A;  3LK5 A;  2Z4Y A;  5ILH A;  1UBY A;  3TS7 A;  5ILY A;  2Q58 A;  4KK2 A;  5H9D A;  4DEM F;  4F6X A;  3OAB B;  1WL2 A;  1VG3 A;  4F62 A;  1YYU A;  1VG4 A;  4KQU A;  1PS1 A;  4XQT F;  1N1B A;  3DYH A;  3Q2Z A;  4OKM A;  5AFX A;  2ZCQ A;  1N23 A;  5DGM F;  4EA1 A;  3DYF A;  2F9K F;  2RAH A;  1RQI A;  4KUX A;  1UBW A;  4RXD A;  2Z4X A;  3VJB A;  3PYA A;  3ACY A;  3M9U A;  1WL1 A;  4LUU A;  3TFV A;  3WJK A;  1EZF A;  3WE9 A;  5ERO A;  3M02 A;  2FTZ A;  2PS4 A;  3SDU A;  3AE0 A;  4PVX F;  4KWD A;  1V4I A;  1N21 A;  2OA6 A;  3ICM A;  3PH7 A;  4LTZ A;  2E95 A;  4RXE A;  3LEE A;  5AYP A;  4LZ0 A;  2O1O A;  2AEK A;  3M0G A;  3TC1 A;  2Z50 A;  4FJQ A;  5JV0 F;  3RMG A;  4KVD A;  4F6V A;  3Q1O A;  3WCM A;  3OYR A;  3BNY A;  3ZL6 A;  3LDW A;  2ZCR A;  4L2X F;  5DHI A;  5ILD A;  5A0K A;  4NFK F;  3WCH A;  2Q80 A;  3S4J A;  5E8L A;  1WL0 A;  4GP1 A;  1V4E A;  2AZJ A;  4DWG A;  5B0L A;  5ILJ A;  2J1P A;  3WCD A;  3QKC A;  4DHD A;  5DW7 A;  3P8R A;  3NF2 A;  3N3L F;  4DXJ A;  3WJN A;  3KBK A;  2J1O A;  2E8X A;  1YYQ A;  3LGK A;  4KPJ A;  1WKZ A;  3N1V F;  2Q9Y A;  1KIZ A;  2E8V A;  1VG2 A;  3LGZ B;  3NPK A;  3Q2Q A;  3OAC B;  4MC8 A;  4P0V A;  2DH4 A;  2OPM A;  3G4D A;  1V4J A;  2E90 A;  3AQC B;  3V1V A;  1KIY A;  4LTV A;  1N22 A;  4KKM A;  3SAE A;  4EA2 A;  1YQ7 A;  4LZC A;  3ADZ A;  3EZ3 A;  2E94 A;  3MAV A;  2PS6 A;  3VJ8 A;  3SDV A;  5B0I A;  3WEG A;  5B01 A;  4JXY A;  2ZEV A;  5DHK A;  3KRA B;  3KRP A;  1YHL A;  4KQS A;  4LA6 A;  1RQJ A;  3WCF A;  3P5R A;  5IL3 A;  3PDE A;  4LLT A;  3VJC A;  5B0J A;  1WMW A;  5E8H A;  3N45 F;  3EFQ A;  3VJ9 A;  3ICK A;  2F8Z F;  3KRC A;  3LSN A;  3M01 A;  5DJR F;  2E91 A;  3WCI A;  3IPI A;  5AEL A;  1V4H A;  5C05 A;  3TFP A;  1HM4 A;  2ZY1 A;  4KVY A;  3WCA A;  3N0F A;  3CP6 A;  3WSB A;  4NKF A;  4LFV F;  3LOM A;  5EAT A;  3OAB A;  3ZMB A;  4LIX A;  3ASX A;  4JYX A;  5HN8 A;  4LA5 A;  2QIS A;  3RBM A;  3ID0 A;  1YHM A;  2AZL A;  3LZ9 A;  2Q9Z A;  5A0J A;  4XQR F;  3WCB A;  5DJP F;  4LPH F;  5HN7 A;  2F7M F;  4QXS F;  4LZ3 A;  2ONG A;  2AEL A;  2EWG A;  4KVI A;  5ERM A;  3ZMC A;  4KQ5 A;  3AQB B;  1VG7 A;  4EA0 A;  4OGU A;  3N6K F;  2VF6 A;  4P0W A;  5EAS A;  3N5J F;  2Z4W A;  2AZK A;  5DGS F;  1YJ4 A;  5IL8 A;  3KRO B;  4ZQ8 A;  4E1E A;  3KRF B;  3RYE A;  4UMJ A;  1YV5 A;  4MC3 A;  1V4K A;  3TFN A;  3ICZ A;  3RYW A;  2E8W A;  4NUA A;  5ILZ A;  5IMI A;  3B7L A;  3IBA A;  2H8O A;  4H5E F;  5ILI A;  4NFI F;  1DI1 A;  4RYP A;  3WJO A;  1DGP A;  2OPN A;  1N24 A;  5B0M A;  4GP2 A;  3WCL A;  3WEJ A;  5E8K A;  4OKZ A;  3LG5 A;  4H5D F;  3ACX A;  3N49 F;  4JZX A;  1N1Z A;  1ZW5 A;  3KRP B;  2F94 F;  2ZCS A;  5JV1 F;  1YYR A;  2PS7 A;  3NRI A;  4H5C F;  5AHU B;  5JV2 F;  3V1X A;  2J5C A;  3VJE A;  4LXW A;  2P1C A;  3P41 A;  4FP4 A;  2E93 A;  3LJI A;  1HM7 A;  5B02 A;  3WEH A;  5I1U A;  4KVW A;  2ONH A;  5HN9 A;  3MZV A;  3WCE A;  1UBV A;  3WEI A;  3W7F A;  2ZCO A;  3N46 F;  5JA0 F;  4LPG F;  3V66 A;  4RXC A;  5HNA A;  5IVG A;  4Q23 A;  3OAC A;  3M00 A;  5B00 A;  1FPS A;  5IK9 A;  3ICN A;  4LOB A;  1HXC A;  2I19 A;  2Z7I A;  4QPF A;  5DIQ F;  5IMP A;  4OMG A;  2F92 F;  5ER8 A;  5IKH A;  2F8C F;  1RTR A;  4JVJ F;  3SDT A;  5IKA A;  4NFJ F;  1VG6 A;  4OMH A;  3WEF A;  5IMN A;  3VJD A;  3N3D A;  1HX9 A;  4NKE A;  5ILK A;  4RXA A;  5ERN A;  3LMD A;  3KRA A;  3NPR A;  5IK0 A;  1WY0 A;  2AET A;  3WCG A;  3KB9 A;  4GAX A;  3SDR A;  4N1Z F;  4RNQ A;  2Z78 A;  4E9U A;  3DYG A;  4WK5 A;  3ZOU A;  4LFG A;  5JUZ F;  4GA3 A;  3N0G A;  4KPD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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