2F92F

Crystal structure of human fpps in complex with alendronate
Total Genus 138
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
138
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl Diphosphate Synthase
publication title Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 138
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2005-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2f92F00
2PS7A 4H5EF 4KVIA 1EZFA 4F6VA 4P0WA 5DHIA 5ILKA 3WCJA 5CG5A 1KIZA 1RQJA 5IL8A 4DZWA 1YHMA 4LOBA 1N1ZA 3WCLA 3WJNA 5E8KA 5A0IA 3TFPA 3ZCDA 1HX9A 4NFJF 3DYFA 4RXAA 1V4IA 1PS1A 2F89F 4LFGA 5B0JA 3WCHA 1WY0A 3VJDA 3LGKA 4FP4A 1RQIA 3BNXA 5E8LA 5IK9A 2PS4A 3KBKA 1N21A 3W7FA 5JUZF 3ZMCA 4QPFA 3TFNA 4KWDA 3AQCB 5H9DA 2F8ZF 2Z78A 4Q23A 3ICKA 4E1EA 5ERMA 1HXAA 1YHLA 4KPJA 1WL0A 5IVGA 3PKOA 2AZJA 3N3LF 3WSBA 4DWBA 3ZMBA 3G4FA 3MZVA 3WE9A 2Q9YA 4E9UA 3CC9A 5DHKA 4OMGA 2ZY1A 2F92F 4LXWA 2ZCOA 4EA1A 5EAUA 2E4OA 5IKAA 3OACA 3N1WF 5B02A 3N0GA 4LTVA 4LTZA 3LSNA 3VJBA 2PS5A 3Q30A 4LLTA 4EA2A 5AELA 3DYGA 2ONHA 4PVYF 4E9ZA 1UBVA 2Z4ZA 5ER8A 5HN8A 3LK5A 4KPDA 3RMGA 1UBYA 3N6KF 2F7MF 4LZCA 2OPMA 3ACYA 3QKCA 3ICNA 3LG5A 3EGTA 5DW7A 3CP6A 4DHDA 5B0IA 5B0LA 3WJOA 2F94F 2ZCQA 2AZKA 2ZCSA 3P5PA 4LUUA 1N1BA 2Z4VA 3OACB 5EASA 5IM1A 3KB9A 3AQ0A 1FPSA 3ACWA 4NKEA 4MC3A 2ONGA 5B00A 3TFVA 1HM7A 5DGSF 2AZLA 3LOMA 2J5CA 3G4DA 1YHKA 3ID0A 4MC8A 5ILZA 3PDEA 2E94A 2E8UA 3ASXA 5IKHA 5IK0A 3N5HF 3M00A 4KUXA 1YYRA 4L2XF 5JV1F 5DGMF 5AFXA 5JV0F 4GA3A 3P8LA 4MC0A 2PS8A 3WEHA 1HXCA 4LA6A 5ILHA 2DH4A 3NF2A 2VF6A 5I1UA 3KRFB 3N1VF 4LLSA 3M02A 4KVDA 3PH7A 4LZ3A 3Q2ZA 1HXGA 3S4JA 3WEKA 5EATA 4NFKF 5EROA 4KK2A 1V4EA 5JA0F 4N1ZF 4GP2A 3M01A 1UBXA 3LGZB 1JFGA 4JVJF 4XQSF 4RXEA 4RXCA 2E95A 4LZ0A 2E8XA 5AHUB 2OGDA 3KRCB 2P1CA 3WCIA 4DWGA 3ZL6A 1N20A 5A0JA 3OABA 3WEJA 3SDTA 4JXNA 5HN7A 4LPGF 3KROB 4OKMA 3KRAB 4KVWA 3KRPA 4KKMA 4NUAA 2Z4XA 2Z50A 4P0VA 1VG6A 3VJAA 3LVSA 4F62A 3NRIA 3S9VA 2OPNA 3TS7A 3CKEA 3QQVA 3AE0A 3RBMA 4KQSA 5DZ2A 3IBAA 4H5DF 3LMDA 3V1XA 3ICZA 3P5RA 5ILDA 4RYPA 5B03A 3LDWA 4RNQA 3ZOUA 1KIYA 2Q80A 2Z52A 3PYBA 4DEMF 3KRFA 3PYAA 2Z4WA 3SDVA 4OGUA 2RAHA 2I19A 1WL2A 2ZCRA 4LFEA 4LPHF 3N5JF 4GP1A 3WCBA 4OKZA 1DI1A 2J1OA 4XQRF 5IMNA 4LFVF 3ACXA 3VJ9A 5JV2F 5B01A 3WCAA 3OABB 5HNAA 2J1PA 4PVXF 3LEEA 5C05A 3TC1A 3NPRA 1WKZA 2O1OA 3AQBB 5E8HA 3KRPB 3P8RA 1VG3A 3SDQA 5ERNA 4DXJA 3B7LA 3DYHA 4JXYA 4HD1A 3WCEA 2AETA 1WL1A 5B0MA 3SDRA 5DGNF 2E90A 4NG6A 3KRCA 1RTRA 4ZQ8A 5DIQF 1V4JA 3P41A 1V4KA 4P0XA 1WL3A 3M0GA 2AEKA 1VG2A 5KSXF 2Q58A 5CG6A 3KROA 5B0KA 3KRAA 3WEGA 4N9UA 1YYUA 4JZXA 4KVYA 2E91A 3RYWA 4UMJA 3Q2QA 2FORA 5IMPA 2AELA 3N0FA 4QXSF 4F6XA 5IL3A 3VJEA 3EFQA 4JZBA 4RXDA 3LJIA 1VG4A 2E8VA 3N3DA 4XQTF 3WSAA 3LLWA 3WCFA 5ILIA 4NKFA 1YQ7A 5IK6A 3SDUA 3LZ9A 2E8WA 5ILJA 2PS6A 1YYQA 3OYRA 2Q9ZA 3WC9A 3WCDA 3WCGA 3Q1OA 4OMHA 3WJKA 4NFIF 4LIXA 3UCAA 4FJQA 3BNYA 1JFAA 1N22A 2Z4YA 5AYPA 1ZW5A 2QISA 4KQ5A 2OA6A 3WEIA 2ZEUA 5DJVF 3IPIA 5A0KA 3V66A 4GAXA 4KQUA 4DI5A 5ILYA 1DGPA 3SAEA 5HN9A 3VJ8A 1YV5A 1WMWA 1VG7A 3N49F 5DJPF 2E92A 2ZEVA 5IN8A 3V1VA 3M9UA 4H5CF 2FTZA 4KFAA 3ICMA 3VJCA 2E93A 3APZA 4LA5A 3WEFA 3N46F 3EZ3A 1HM4A 4JYXA 2EWGA 2F8CF 3RYEA 3ADZA 2E8TA 1V4HA 1YYTA 5DJRF 1YJ4A 4WK5A 3N45F 3WCCA 2Z7HA 2H8OA 2F9KF 4K10A 2Z7IA 1N23A 1YYSA 3NPKA 3MAVA 3WCMA 4EA0A 1N24A 1UBWA 5IMIA
chains in the Genus database with same CATH superfamily
2PS7A 4H5EF 4KVIA 1EZFA 4F6VA 4P0WA 5DHIA 5ILKA 3WCJA 5CG5A 1KIZA 1RQJA 5IL8A 4DZWA 1YHMA 4LOBA 1N1ZA 3WCLA 3WJNA 5E8KA 5A0IA 3TFPA 3ZCDA 1HX9A 4NFJF 3DYFA 4RXAA 1V4IA 1PS1A 2F89F 4LFGA 5B0JA 3WCHA 1WY0A 3VJDA 3LGKA 4FP4A 1RQIA 3BNXA 5E8LA 5IK9A 2PS4A 3KBKA 1N21A 3W7FA 5JUZF 3ZMCA 4QPFA 3TFNA 4KWDA 3AQCB 5H9DA 2F8ZF 2Z78A 4Q23A 3ICKA 4E1EA 5ERMA 1HXAA 1YHLA 4KPJA 1WL0A 5IVGA 3PKOA 2AZJA 3N3LF 3WSBA 4DWBA 3ZMBA 3G4FA 3MZVA 3WE9A 2Q9YA 4E9UA 3CC9A 5DHKA 4OMGA 2ZY1A 2F92F 4LXWA 2ZCOA 4EA1A 5EAUA 2E4OA 5IKAA 3OACA 3N1WF 5B02A 3N0GA 4LTVA 4LTZA 3LSNA 3VJBA 2PS5A 3Q30A 4LLTA 4EA2A 5AELA 3DYGA 2ONHA 4PVYF 4E9ZA 1UBVA 2Z4ZA 5ER8A 5HN8A 3LK5A 4KPDA 3RMGA 1UBYA 3N6KF 2F7MF 4LZCA 2OPMA 3ACYA 3QKCA 3ICNA 3LG5A 3EGTA 5DW7A 3CP6A 4DHDA 5B0IA 5B0LA 3WJOA 2F94F 2ZCQA 2AZKA 2ZCSA 3P5PA 4LUUA 1N1BA 2Z4VA 3OACB 5EASA 5IM1A 3KB9A 3AQ0A 1FPSA 3ACWA 4NKEA 4MC3A 2ONGA 5B00A 3TFVA 1HM7A 5DGSF 2AZLA 3LOMA 2J5CA 3G4DA 1YHKA 3ID0A 4MC8A 5ILZA 3PDEA 2E94A 2E8UA 3ASXA 5IKHA 5IK0A 3N5HF 3M00A 4KUXA 1YYRA 4L2XF 5JV1F 5DGMF 5AFXA 5JV0F 4GA3A 3P8LA 4MC0A 2PS8A 3WEHA 1HXCA 4LA6A 5ILHA 2DH4A 3NF2A 2VF6A 5I1UA 3KRFB 3N1VF 4LLSA 3M02A 4KVDA 3PH7A 4LZ3A 3Q2ZA 1HXGA 3S4JA 3WEKA 5EATA 4NFKF 5EROA 4KK2A 1V4EA 5JA0F 4N1ZF 4GP2A 3M01A 1UBXA 3LGZB 1JFGA 4JVJF 4XQSF 4RXEA 4RXCA 2E95A 4LZ0A 2E8XA 5AHUB 2OGDA 3KRCB 2P1CA 3WCIA 4DWGA 3ZL6A 1N20A 5A0JA 3OABA 3WEJA 3SDTA 4JXNA 5HN7A 4LPGF 3KROB 4OKMA 3KRAB 4KVWA 3KRPA 4KKMA 4NUAA 2Z4XA 2Z50A 4P0VA 1VG6A 3VJAA 3LVSA 4F62A 3NRIA 3S9VA 2OPNA 3TS7A 3CKEA 3QQVA 3AE0A 3RBMA 4KQSA 5DZ2A 3IBAA 4H5DF 3LMDA 3V1XA 3ICZA 3P5RA 5ILDA 4RYPA 5B03A 3LDWA 4RNQA 3ZOUA 1KIYA 2Q80A 2Z52A 3PYBA 4DEMF 3KRFA 3PYAA 2Z4WA 3SDVA 4OGUA 2RAHA 2I19A 1WL2A 2ZCRA 4LFEA 4LPHF 3N5JF 4GP1A 3WCBA 4OKZA 1DI1A 2J1OA 4XQRF 5IMNA 4LFVF 3ACXA 3VJ9A 5JV2F 5B01A 3WCAA 3OABB 5HNAA 2J1PA 4PVXF 3LEEA 5C05A 3TC1A 3NPRA 1WKZA 2O1OA 3AQBB 5E8HA 3KRPB 3P8RA 1VG3A 3SDQA 5ERNA 4DXJA 3B7LA 3DYHA 4JXYA 4HD1A 3WCEA 2AETA 1WL1A 5B0MA 3SDRA 5DGNF 2E90A 4NG6A 3KRCA 1RTRA 4ZQ8A 5DIQF 1V4JA 3P41A 1V4KA 4P0XA 1WL3A 3M0GA 2AEKA 1VG2A 5KSXF 2Q58A 5CG6A 3KROA 5B0KA 3KRAA 3WEGA 4N9UA 1YYUA 4JZXA 4KVYA 2E91A 3RYWA 4UMJA 3Q2QA 2FORA 5IMPA 2AELA 3N0FA 4QXSF 4F6XA 5IL3A 3VJEA 3EFQA 4JZBA 4RXDA 3LJIA 1VG4A 2E8VA 3N3DA 4XQTF 3WSAA 3LLWA 3WCFA 5ILIA 4NKFA 1YQ7A 5IK6A 3SDUA 3LZ9A 2E8WA 5ILJA 2PS6A 1YYQA 3OYRA 2Q9ZA 3WC9A 3WCDA 3WCGA 3Q1OA 4OMHA 3WJKA 4NFIF 4LIXA 3UCAA 4FJQA 3BNYA 1JFAA 1N22A 2Z4YA 5AYPA 1ZW5A 2QISA 4KQ5A 2OA6A 3WEIA 2ZEUA 5DJVF 3IPIA 5A0KA 3V66A 4GAXA 4KQUA 4DI5A 5ILYA 1DGPA 3SAEA 5HN9A 3VJ8A 1YV5A 1WMWA 1VG7A 3N49F 5DJPF 2E92A 2ZEVA 5IN8A 3V1VA 3M9UA 4H5CF 2FTZA 4KFAA 3ICMA 3VJCA 2E93A 3APZA 4LA5A 3WEFA 3N46F 3EZ3A 1HM4A 4JYXA 2EWGA 2F8CF 3RYEA 3ADZA 2E8TA 1V4HA 1YYTA 5DJRF 1YJ4A 4WK5A 3N45F 3WCCA 2Z7HA 2H8OA 2F9KF 4K10A 2Z7IA 1N23A 1YYSA 3NPKA 3MAVA 3WCMA 4EA0A 1N24A 1UBWA 5IMIA
chains in the Genus database with same CATH topology
2PS7A 4H5EF 4KVIA 1EZFA 4F6VA 4P0WA 5DHIA 5ILKA 3WCJA 5CG5A 1KIZA 1RQJA 5IL8A 4DZWA 1YHMA 4LOBA 1N1ZA 3WCLA 3WJNA 5E8KA 5A0IA 3TFPA 3ZCDA 1HX9A 4NFJF 3DYFA 4RXAA 1V4IA 1PS1A 2F89F 4LFGA 5B0JA 3WCHA 1WY0A 3VJDA 3LGKA 4FP4A 1RQIA 3BNXA 5E8LA 5IK9A 2PS4A 3KBKA 1N21A 3W7FA 5JUZF 3ZMCA 4QPFA 3TFNA 4KWDA 3AQCB 5H9DA 2F8ZF 2Z78A 4Q23A 3ICKA 4E1EA 5ERMA 1HXAA 1YHLA 4KPJA 1WL0A 5IVGA 3PKOA 2AZJA 3N3LF 3WSBA 4DWBA 3ZMBA 3G4FA 3MZVA 3WE9A 2Q9YA 4E9UA 3CC9A 5DHKA 4OMGA 2ZY1A 2F92F 4LXWA 2ZCOA 4EA1A 5EAUA 2E4OA 5IKAA 3OACA 3N1WF 5B02A 3N0GA 4LTVA 4LTZA 3LSNA 3VJBA 2PS5A 3Q30A 4LLTA 4EA2A 5AELA 3DYGA 2ONHA 4PVYF 4E9ZA 1UBVA 2Z4ZA 5ER8A 5HN8A 3LK5A 4KPDA 3RMGA 1UBYA 3N6KF 2F7MF 4LZCA 2OPMA 3ACYA 3QKCA 3ICNA 3LG5A 3EGTA 5DW7A 3CP6A 4DHDA 5B0IA 5B0LA 3WJOA 2F94F 2ZCQA 2AZKA 2ZCSA 3P5PA 4LUUA 1N1BA 2Z4VA 3OACB 5EASA 5IM1A 3KB9A 3AQ0A 1FPSA 3ACWA 4NKEA 4MC3A 2ONGA 5B00A 3TFVA 1HM7A 5DGSF 2AZLA 3LOMA 2J5CA 3G4DA 1YHKA 3ID0A 4MC8A 5ILZA 3PDEA 2E94A 2E8UA 3ASXA 5IKHA 5IK0A 3N5HF 3M00A 4KUXA 1YYRA 4L2XF 5JV1F 5DGMF 5AFXA 5JV0F 4GA3A 3P8LA 4MC0A 2PS8A 3WEHA 1HXCA 4LA6A 5ILHA 2DH4A 3NF2A 2VF6A 5I1UA 3KRFB 3N1VF 4LLSA 3M02A 4KVDA 3PH7A 4LZ3A 3Q2ZA 1HXGA 3S4JA 3WEKA 5EATA 4NFKF 5EROA 4KK2A 1V4EA 5JA0F 4N1ZF 4GP2A 3M01A 1UBXA 3LGZB 1JFGA 4JVJF 4XQSF 4RXEA 4RXCA 2E95A 4LZ0A 2E8XA 5AHUB 2OGDA 3KRCB 2P1CA 3WCIA 4DWGA 3ZL6A 1N20A 5A0JA 3OABA 3WEJA 3SDTA 4JXNA 5HN7A 4LPGF 3KROB 4OKMA 3KRAB 4KVWA 3KRPA 4KKMA 4NUAA 2Z4XA 2Z50A 4P0VA 1VG6A 3VJAA 3LVSA 4F62A 3NRIA 3S9VA 2OPNA 3TS7A 3CKEA 3QQVA 3AE0A 3RBMA 4KQSA 5DZ2A 3IBAA 4H5DF 3LMDA 3V1XA 3ICZA 3P5RA 5ILDA 4RYPA 5B03A 3LDWA 4RNQA 3ZOUA 1KIYA 2Q80A 2Z52A 3PYBA 4DEMF 3KRFA 3PYAA 2Z4WA 3SDVA 4OGUA 2RAHA 2I19A 1WL2A 2ZCRA 4LFEA 4LPHF 3N5JF 4GP1A 3WCBA 4OKZA 1DI1A 2J1OA 4XQRF 5IMNA 4LFVF 3ACXA 3VJ9A 5JV2F 5B01A 3WCAA 3OABB 5HNAA 2J1PA 4PVXF 3LEEA 5C05A 3TC1A 3NPRA 1WKZA 2O1OA 3AQBB 5E8HA 3KRPB 3P8RA 1VG3A 3SDQA 5ERNA 4DXJA 3B7LA 3DYHA 4JXYA 4HD1A 3WCEA 2AETA 1WL1A 5B0MA 3SDRA 5DGNF 2E90A 4NG6A 3KRCA 1RTRA 4ZQ8A 5DIQF 1V4JA 3P41A 1V4KA 4P0XA 1WL3A 3M0GA 2AEKA 1VG2A 5KSXF 2Q58A 5CG6A 3KROA 5B0KA 3KRAA 3WEGA 4N9UA 1YYUA 4JZXA 4KVYA 2E91A 3RYWA 4UMJA 3Q2QA 2FORA 5IMPA 2AELA 3N0FA 4QXSF 4F6XA 5IL3A 3VJEA 3EFQA 4JZBA 4RXDA 3LJIA 1VG4A 2E8VA 3N3DA 4XQTF 3WSAA 3LLWA 3WCFA 5ILIA 4NKFA 1YQ7A 5IK6A 3SDUA 3LZ9A 2E8WA 5ILJA 2PS6A 1YYQA 3OYRA 2Q9ZA 3WC9A 3WCDA 3WCGA 3Q1OA 4OMHA 3WJKA 4NFIF 4LIXA 3UCAA 4FJQA 3BNYA 1JFAA 1N22A 2Z4YA 5AYPA 1ZW5A 2QISA 4KQ5A 2OA6A 3WEIA 2ZEUA 5DJVF 3IPIA 5A0KA 3V66A 4GAXA 4KQUA 4DI5A 5ILYA 1DGPA 3SAEA 5HN9A 3VJ8A 1YV5A 1WMWA 1VG7A 3N49F 5DJPF 2E92A 2ZEVA 5IN8A 3V1VA 3M9UA 4H5CF 2FTZA 4KFAA 3ICMA 3VJCA 2E93A 3APZA 4LA5A 3WEFA 3N46F 3EZ3A 1HM4A 4JYXA 2EWGA 2F8CF 3RYEA 3ADZA 2E8TA 1V4HA 1YYTA 5DJRF 1YJ4A 4WK5A 3N45F 3WCCA 2Z7HA 2H8OA 2F9KF 4K10A 2Z7IA 1N23A 1YYSA 3NPKA 3MAVA 3WCMA 4EA0A 1N24A 1UBWA 5IMIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PS7 A;  4H5E F;  4KVI A;  1EZF A;  4F6V A;  4P0W A;  5DHI A;  5ILK A;  3WCJ A;  5CG5 A;  1KIZ A;  1RQJ A;  5IL8 A;  4DZW A;  1YHM A;  4LOB A;  1N1Z A;  3WCL A;  3WJN A;  5E8K A;  5A0I A;  3TFP A;  3ZCD A;  1HX9 A;  4NFJ F;  3DYF A;  4RXA A;  1V4I A;  1PS1 A;  2F89 F;  4LFG A;  5B0J A;  3WCH A;  1WY0 A;  3VJD A;  3LGK A;  4FP4 A;  1RQI A;  3BNX A;  5E8L A;  5IK9 A;  2PS4 A;  3KBK A;  1N21 A;  3W7F A;  5JUZ F;  3ZMC A;  4QPF A;  3TFN A;  4KWD A;  3AQC B;  5H9D A;  2F8Z F;  2Z78 A;  4Q23 A;  3ICK A;  4E1E A;  5ERM A;  1HXA A;  1YHL A;  4KPJ A;  1WL0 A;  5IVG A;  3PKO A;  2AZJ A;  3N3L F;  3WSB A;  4DWB A;  3ZMB A;  3G4F A;  3MZV A;  3WE9 A;  2Q9Y A;  4E9U A;  3CC9 A;  5DHK A;  4OMG A;  2ZY1 A;  2F92 F;  4LXW A;  2ZCO A;  4EA1 A;  5EAU A;  2E4O A;  5IKA A;  3OAC A;  3N1W F;  5B02 A;  3N0G A;  4LTV A;  4LTZ A;  3LSN A;  3VJB A;  2PS5 A;  3Q30 A;  4LLT A;  4EA2 A;  5AEL A;  3DYG A;  2ONH A;  4PVY F;  4E9Z A;  1UBV A;  2Z4Z A;  5ER8 A;  5HN8 A;  3LK5 A;  4KPD A;  3RMG A;  1UBY A;  3N6K F;  2F7M F;  4LZC A;  2OPM A;  3ACY A;  3QKC A;  3ICN A;  3LG5 A;  3EGT A;  5DW7 A;  3CP6 A;  4DHD A;  5B0I A;  5B0L A;  3WJO A;  2F94 F;  2ZCQ A;  2AZK A;  2ZCS A;  3P5P A;  4LUU A;  1N1B A;  2Z4V A;  3OAC B;  5EAS A;  5IM1 A;  3KB9 A;  3AQ0 A;  1FPS A;  3ACW A;  4NKE A;  4MC3 A;  2ONG A;  5B00 A;  3TFV A;  1HM7 A;  5DGS F;  2AZL A;  3LOM A;  2J5C A;  3G4D A;  1YHK A;  3ID0 A;  4MC8 A;  5ILZ A;  3PDE A;  2E94 A;  2E8U A;  3ASX A;  5IKH A;  5IK0 A;  3N5H F;  3M00 A;  4KUX A;  1YYR A;  4L2X F;  5JV1 F;  5DGM F;  5AFX A;  5JV0 F;  4GA3 A;  3P8L A;  4MC0 A;  2PS8 A;  3WEH A;  1HXC A;  4LA6 A;  5ILH A;  2DH4 A;  3NF2 A;  2VF6 A;  5I1U A;  3KRF B;  3N1V F;  4LLS A;  3M02 A;  4KVD A;  3PH7 A;  4LZ3 A;  3Q2Z A;  1HXG A;  3S4J A;  3WEK A;  5EAT A;  4NFK F;  5ERO A;  4KK2 A;  1V4E A;  5JA0 F;  4N1Z F;  4GP2 A;  3M01 A;  1UBX A;  3LGZ B;  1JFG A;  4JVJ F;  4XQS F;  4RXE A;  4RXC A;  2E95 A;  4LZ0 A;  2E8X A;  5AHU B;  2OGD A;  3KRC B;  2P1C A;  3WCI A;  4DWG A;  3ZL6 A;  1N20 A;  5A0J A;  3OAB A;  3WEJ A;  3SDT A;  4JXN A;  5HN7 A;  4LPG F;  3KRO B;  4OKM A;  3KRA B;  4KVW A;  3KRP A;  4KKM A;  4NUA A;  2Z4X A;  2Z50 A;  4P0V A;  1VG6 A;  3VJA A;  3LVS A;  4F62 A;  3NRI A;  3S9V A;  2OPN A;  3TS7 A;  3CKE A;  3QQV A;  3AE0 A;  3RBM A;  4KQS A;  5DZ2 A;  3IBA A;  4H5D F;  3LMD A;  3V1X A;  3ICZ A;  3P5R A;  5ILD A;  4RYP A;  5B03 A;  3LDW A;  4RNQ A;  3ZOU A;  1KIY A;  2Q80 A;  2Z52 A;  3PYB A;  4DEM F;  3KRF A;  3PYA A;  2Z4W A;  3SDV A;  4OGU A;  2RAH A;  2I19 A;  1WL2 A;  2ZCR A;  4LFE A;  4LPH F;  3N5J F;  4GP1 A;  3WCB A;  4OKZ A;  1DI1 A;  2J1O A;  4XQR F;  5IMN A;  4LFV F;  3ACX A;  3VJ9 A;  5JV2 F;  5B01 A;  3WCA A;  3OAB B;  5HNA A;  2J1P A;  4PVX F;  3LEE A;  5C05 A;  3TC1 A;  3NPR A;  1WKZ A;  2O1O A;  3AQB B;  5E8H A;  3KRP B;  3P8R A;  1VG3 A;  3SDQ A;  5ERN A;  4DXJ A;  3B7L A;  3DYH A;  4JXY A;  4HD1 A;  3WCE A;  2AET A;  1WL1 A;  5B0M A;  3SDR A;  5DGN F;  2E90 A;  4NG6 A;  3KRC A;  1RTR A;  4ZQ8 A;  5DIQ F;  1V4J A;  3P41 A;  1V4K A;  4P0X A;  1WL3 A;  3M0G A;  2AEK A;  1VG2 A;  5KSX F;  2Q58 A;  5CG6 A;  3KRO A;  5B0K A;  3KRA A;  3WEG A;  4N9U A;  1YYU A;  4JZX A;  4KVY A;  2E91 A;  3RYW A;  4UMJ A;  3Q2Q A;  2FOR A;  5IMP A;  2AEL A;  3N0F A;  4QXS F;  4F6X A;  5IL3 A;  3VJE A;  3EFQ A;  4JZB A;  4RXD A;  3LJI A;  1VG4 A;  2E8V A;  3N3D A;  4XQT F;  3WSA A;  3LLW A;  3WCF A;  5ILI A;  4NKF A;  1YQ7 A;  5IK6 A;  3SDU A;  3LZ9 A;  2E8W A;  5ILJ A;  2PS6 A;  1YYQ A;  3OYR A;  2Q9Z A;  3WC9 A;  3WCD A;  3WCG A;  3Q1O A;  4OMH A;  3WJK A;  4NFI F;  4LIX A;  3UCA A;  4FJQ A;  3BNY A;  1JFA A;  1N22 A;  2Z4Y A;  5AYP A;  1ZW5 A;  2QIS A;  4KQ5 A;  2OA6 A;  3WEI A;  2ZEU A;  5DJV F;  3IPI A;  5A0K A;  3V66 A;  4GAX A;  4KQU A;  4DI5 A;  5ILY A;  1DGP A;  3SAE A;  5HN9 A;  3VJ8 A;  1YV5 A;  1WMW A;  1VG7 A;  3N49 F;  5DJP F;  2E92 A;  2ZEV A;  5IN8 A;  3V1V A;  3M9U A;  4H5C F;  2FTZ A;  4KFA A;  3ICM A;  3VJC A;  2E93 A;  3APZ A;  4LA5 A;  3WEF A;  3N46 F;  3EZ3 A;  1HM4 A;  4JYX A;  2EWG A;  2F8C F;  3RYE A;  3ADZ A;  2E8T A;  1V4H A;  1YYT A;  5DJR F;  1YJ4 A;  4WK5 A;  3N45 F;  3WCC A;  2Z7H A;  2H8O A;  2F9K F;  4K10 A;  2Z7I A;  1N23 A;  1YYS A;  3NPK A;  3MAV A;  3WCM A;  4EA0 A;  1N24 A;  1UBW A;  5IMI A; 
#chains in the Genus database with same CATH topology
 2PS7 A;  4H5E F;  4KVI A;  1EZF A;  4F6V A;  4P0W A;  5DHI A;  5ILK A;  3WCJ A;  5CG5 A;  1KIZ A;  1RQJ A;  5IL8 A;  4DZW A;  1YHM A;  4LOB A;  1N1Z A;  3WCL A;  3WJN A;  5E8K A;  5A0I A;  3TFP A;  3ZCD A;  1HX9 A;  4NFJ F;  3DYF A;  4RXA A;  1V4I A;  1PS1 A;  2F89 F;  4LFG A;  5B0J A;  3WCH A;  1WY0 A;  3VJD A;  3LGK A;  4FP4 A;  1RQI A;  3BNX A;  5E8L A;  5IK9 A;  2PS4 A;  3KBK A;  1N21 A;  3W7F A;  5JUZ F;  3ZMC A;  4QPF A;  3TFN A;  4KWD A;  3AQC B;  5H9D A;  2F8Z F;  2Z78 A;  4Q23 A;  3ICK A;  4E1E A;  5ERM A;  1HXA A;  1YHL A;  4KPJ A;  1WL0 A;  5IVG A;  3PKO A;  2AZJ A;  3N3L F;  3WSB A;  4DWB A;  3ZMB A;  3G4F A;  3MZV A;  3WE9 A;  2Q9Y A;  4E9U A;  3CC9 A;  5DHK A;  4OMG A;  2ZY1 A;  2F92 F;  4LXW A;  2ZCO A;  4EA1 A;  5EAU A;  2E4O A;  5IKA A;  3OAC A;  3N1W F;  5B02 A;  3N0G A;  4LTV A;  4LTZ A;  3LSN A;  3VJB A;  2PS5 A;  3Q30 A;  4LLT A;  4EA2 A;  5AEL A;  3DYG A;  2ONH A;  4PVY F;  4E9Z A;  1UBV A;  2Z4Z A;  5ER8 A;  5HN8 A;  3LK5 A;  4KPD A;  3RMG A;  1UBY A;  3N6K F;  2F7M F;  4LZC A;  2OPM A;  3ACY A;  3QKC A;  3ICN A;  3LG5 A;  3EGT A;  5DW7 A;  3CP6 A;  4DHD A;  5B0I A;  5B0L A;  3WJO A;  2F94 F;  2ZCQ A;  2AZK A;  2ZCS A;  3P5P A;  4LUU A;  1N1B A;  2Z4V A;  3OAC B;  5EAS A;  5IM1 A;  3KB9 A;  3AQ0 A;  1FPS A;  3ACW A;  4NKE A;  4MC3 A;  2ONG A;  5B00 A;  3TFV A;  1HM7 A;  5DGS F;  2AZL A;  3LOM A;  2J5C A;  3G4D A;  1YHK A;  3ID0 A;  4MC8 A;  5ILZ A;  3PDE A;  2E94 A;  2E8U A;  3ASX A;  5IKH A;  5IK0 A;  3N5H F;  3M00 A;  4KUX A;  1YYR A;  4L2X F;  5JV1 F;  5DGM F;  5AFX A;  5JV0 F;  4GA3 A;  3P8L A;  4MC0 A;  2PS8 A;  3WEH A;  1HXC A;  4LA6 A;  5ILH A;  2DH4 A;  3NF2 A;  2VF6 A;  5I1U A;  3KRF B;  3N1V F;  4LLS A;  3M02 A;  4KVD A;  3PH7 A;  4LZ3 A;  3Q2Z A;  1HXG A;  3S4J A;  3WEK A;  5EAT A;  4NFK F;  5ERO A;  4KK2 A;  1V4E A;  5JA0 F;  4N1Z F;  4GP2 A;  3M01 A;  1UBX A;  3LGZ B;  1JFG A;  4JVJ F;  4XQS F;  4RXE A;  4RXC A;  2E95 A;  4LZ0 A;  2E8X A;  5AHU B;  2OGD A;  3KRC B;  2P1C A;  3WCI A;  4DWG A;  3ZL6 A;  1N20 A;  5A0J A;  3OAB A;  3WEJ A;  3SDT A;  4JXN A;  5HN7 A;  4LPG F;  3KRO B;  4OKM A;  3KRA B;  4KVW A;  3KRP A;  4KKM A;  4NUA A;  2Z4X A;  2Z50 A;  4P0V A;  1VG6 A;  3VJA A;  3LVS A;  4F62 A;  3NRI A;  3S9V A;  2OPN A;  3TS7 A;  3CKE A;  3QQV A;  3AE0 A;  3RBM A;  4KQS A;  5DZ2 A;  3IBA A;  4H5D F;  3LMD A;  3V1X A;  3ICZ A;  3P5R A;  5ILD A;  4RYP A;  5B03 A;  3LDW A;  4RNQ A;  3ZOU A;  1KIY A;  2Q80 A;  2Z52 A;  3PYB A;  4DEM F;  3KRF A;  3PYA A;  2Z4W A;  3SDV A;  4OGU A;  2RAH A;  2I19 A;  1WL2 A;  2ZCR A;  4LFE A;  4LPH F;  3N5J F;  4GP1 A;  3WCB A;  4OKZ A;  1DI1 A;  2J1O A;  4XQR F;  5IMN A;  4LFV F;  3ACX A;  3VJ9 A;  5JV2 F;  5B01 A;  3WCA A;  3OAB B;  5HNA A;  2J1P A;  4PVX F;  3LEE A;  5C05 A;  3TC1 A;  3NPR A;  1WKZ A;  2O1O A;  3AQB B;  5E8H A;  3KRP B;  3P8R A;  1VG3 A;  3SDQ A;  5ERN A;  4DXJ A;  3B7L A;  3DYH A;  4JXY A;  4HD1 A;  3WCE A;  2AET A;  1WL1 A;  5B0M A;  3SDR A;  5DGN F;  2E90 A;  4NG6 A;  3KRC A;  1RTR A;  4ZQ8 A;  5DIQ F;  1V4J A;  3P41 A;  1V4K A;  4P0X A;  1WL3 A;  3M0G A;  2AEK A;  1VG2 A;  5KSX F;  2Q58 A;  5CG6 A;  3KRO A;  5B0K A;  3KRA A;  3WEG A;  4N9U A;  1YYU A;  4JZX A;  4KVY A;  2E91 A;  3RYW A;  4UMJ A;  3Q2Q A;  2FOR A;  5IMP A;  2AEL A;  3N0F A;  4QXS F;  4F6X A;  5IL3 A;  3VJE A;  3EFQ A;  4JZB A;  4RXD A;  3LJI A;  1VG4 A;  2E8V A;  3N3D A;  4XQT F;  3WSA A;  3LLW A;  3WCF A;  5ILI A;  4NKF A;  1YQ7 A;  5IK6 A;  3SDU A;  3LZ9 A;  2E8W A;  5ILJ A;  2PS6 A;  1YYQ A;  3OYR A;  2Q9Z A;  3WC9 A;  3WCD A;  3WCG A;  3Q1O A;  4OMH A;  3WJK A;  4NFI F;  4LIX A;  3UCA A;  4FJQ A;  3BNY A;  1JFA A;  1N22 A;  2Z4Y A;  5AYP A;  1ZW5 A;  2QIS A;  4KQ5 A;  2OA6 A;  3WEI A;  2ZEU A;  5DJV F;  3IPI A;  5A0K A;  3V66 A;  4GAX A;  4KQU A;  4DI5 A;  5ILY A;  1DGP A;  3SAE A;  5HN9 A;  3VJ8 A;  1YV5 A;  1WMW A;  1VG7 A;  3N49 F;  5DJP F;  2E92 A;  2ZEV A;  5IN8 A;  3V1V A;  3M9U A;  4H5C F;  2FTZ A;  4KFA A;  3ICM A;  3VJC A;  2E93 A;  3APZ A;  4LA5 A;  3WEF A;  3N46 F;  3EZ3 A;  1HM4 A;  4JYX A;  2EWG A;  2F8C F;  3RYE A;  3ADZ A;  2E8T A;  1V4H A;  1YYT A;  5DJR F;  1YJ4 A;  4WK5 A;  3N45 F;  3WCC A;  2Z7H A;  2H8O A;  2F9K F;  4K10 A;  2Z7I A;  1N23 A;  1YYS A;  3NPK A;  3MAV A;  3WCM A;  4EA0 A;  1N24 A;  1UBW A;  5IMI A; 
#chains in the Genus database with same CATH homology
 2PS7 A;  4H5E F;  4KVI A;  1EZF A;  4F6V A;  4P0W A;  5DHI A;  5ILK A;  3WCJ A;  5CG5 A;  1KIZ A;  1RQJ A;  5IL8 A;  4DZW A;  1YHM A;  4LOB A;  1N1Z A;  3WCL A;  3WJN A;  5E8K A;  5A0I A;  3TFP A;  3ZCD A;  1HX9 A;  4NFJ F;  3DYF A;  4RXA A;  1V4I A;  1PS1 A;  2F89 F;  4LFG A;  5B0J A;  3WCH A;  1WY0 A;  3VJD A;  3LGK A;  4FP4 A;  1RQI A;  3BNX A;  5E8L A;  5IK9 A;  2PS4 A;  3KBK A;  1N21 A;  3W7F A;  5JUZ F;  3ZMC A;  4QPF A;  3TFN A;  4KWD A;  3AQC B;  5H9D A;  2F8Z F;  2Z78 A;  4Q23 A;  3ICK A;  4E1E A;  5ERM A;  1HXA A;  1YHL A;  4KPJ A;  1WL0 A;  5IVG A;  3PKO A;  2AZJ A;  3N3L F;  3WSB A;  4DWB A;  3ZMB A;  3G4F A;  3MZV A;  3WE9 A;  2Q9Y A;  4E9U A;  3CC9 A;  5DHK A;  4OMG A;  2ZY1 A;  2F92 F;  4LXW A;  2ZCO A;  4EA1 A;  5EAU A;  2E4O A;  5IKA A;  3OAC A;  3N1W F;  5B02 A;  3N0G A;  4LTV A;  4LTZ A;  3LSN A;  3VJB A;  2PS5 A;  3Q30 A;  4LLT A;  4EA2 A;  5AEL A;  3DYG A;  2ONH A;  4PVY F;  4E9Z A;  1UBV A;  2Z4Z A;  5ER8 A;  5HN8 A;  3LK5 A;  4KPD A;  3RMG A;  1UBY A;  3N6K F;  2F7M F;  4LZC A;  2OPM A;  3ACY A;  3QKC A;  3ICN A;  3LG5 A;  3EGT A;  5DW7 A;  3CP6 A;  4DHD A;  5B0I A;  5B0L A;  3WJO A;  2F94 F;  2ZCQ A;  2AZK A;  2ZCS A;  3P5P A;  4LUU A;  1N1B A;  2Z4V A;  3OAC B;  5EAS A;  5IM1 A;  3KB9 A;  3AQ0 A;  1FPS A;  3ACW A;  4NKE A;  4MC3 A;  2ONG A;  5B00 A;  3TFV A;  1HM7 A;  5DGS F;  2AZL A;  3LOM A;  2J5C A;  3G4D A;  1YHK A;  3ID0 A;  4MC8 A;  5ILZ A;  3PDE A;  2E94 A;  2E8U A;  3ASX A;  5IKH A;  5IK0 A;  3N5H F;  3M00 A;  4KUX A;  1YYR A;  4L2X F;  5JV1 F;  5DGM F;  5AFX A;  5JV0 F;  4GA3 A;  3P8L A;  4MC0 A;  2PS8 A;  3WEH A;  1HXC A;  4LA6 A;  5ILH A;  2DH4 A;  3NF2 A;  2VF6 A;  5I1U A;  3KRF B;  3N1V F;  4LLS A;  3M02 A;  4KVD A;  3PH7 A;  4LZ3 A;  3Q2Z A;  1HXG A;  3S4J A;  3WEK A;  5EAT A;  4NFK F;  5ERO A;  4KK2 A;  1V4E A;  5JA0 F;  4N1Z F;  4GP2 A;  3M01 A;  1UBX A;  3LGZ B;  1JFG A;  4JVJ F;  4XQS F;  4RXE A;  4RXC A;  2E95 A;  4LZ0 A;  2E8X A;  5AHU B;  2OGD A;  3KRC B;  2P1C A;  3WCI A;  4DWG A;  3ZL6 A;  1N20 A;  5A0J A;  3OAB A;  3WEJ A;  3SDT A;  4JXN A;  5HN7 A;  4LPG F;  3KRO B;  4OKM A;  3KRA B;  4KVW A;  3KRP A;  4KKM A;  4NUA A;  2Z4X A;  2Z50 A;  4P0V A;  1VG6 A;  3VJA A;  3LVS A;  4F62 A;  3NRI A;  3S9V A;  2OPN A;  3TS7 A;  3CKE A;  3QQV A;  3AE0 A;  3RBM A;  4KQS A;  5DZ2 A;  3IBA A;  4H5D F;  3LMD A;  3V1X A;  3ICZ A;  3P5R A;  5ILD A;  4RYP A;  5B03 A;  3LDW A;  4RNQ A;  3ZOU A;  1KIY A;  2Q80 A;  2Z52 A;  3PYB A;  4DEM F;  3KRF A;  3PYA A;  2Z4W A;  3SDV A;  4OGU A;  2RAH A;  2I19 A;  1WL2 A;  2ZCR A;  4LFE A;  4LPH F;  3N5J F;  4GP1 A;  3WCB A;  4OKZ A;  1DI1 A;  2J1O A;  4XQR F;  5IMN A;  4LFV F;  3ACX A;  3VJ9 A;  5JV2 F;  5B01 A;  3WCA A;  3OAB B;  5HNA A;  2J1P A;  4PVX F;  3LEE A;  5C05 A;  3TC1 A;  3NPR A;  1WKZ A;  2O1O A;  3AQB B;  5E8H A;  3KRP B;  3P8R A;  1VG3 A;  3SDQ A;  5ERN A;  4DXJ A;  3B7L A;  3DYH A;  4JXY A;  4HD1 A;  3WCE A;  2AET A;  1WL1 A;  5B0M A;  3SDR A;  5DGN F;  2E90 A;  4NG6 A;  3KRC A;  1RTR A;  4ZQ8 A;  5DIQ F;  1V4J A;  3P41 A;  1V4K A;  4P0X A;  1WL3 A;  3M0G A;  2AEK A;  1VG2 A;  5KSX F;  2Q58 A;  5CG6 A;  3KRO A;  5B0K A;  3KRA A;  3WEG A;  4N9U A;  1YYU A;  4JZX A;  4KVY A;  2E91 A;  3RYW A;  4UMJ A;  3Q2Q A;  2FOR A;  5IMP A;  2AEL A;  3N0F A;  4QXS F;  4F6X A;  5IL3 A;  3VJE A;  3EFQ A;  4JZB A;  4RXD A;  3LJI A;  1VG4 A;  2E8V A;  3N3D A;  4XQT F;  3WSA A;  3LLW A;  3WCF A;  5ILI A;  4NKF A;  1YQ7 A;  5IK6 A;  3SDU A;  3LZ9 A;  2E8W A;  5ILJ A;  2PS6 A;  1YYQ A;  3OYR A;  2Q9Z A;  3WC9 A;  3WCD A;  3WCG A;  3Q1O A;  4OMH A;  3WJK A;  4NFI F;  4LIX A;  3UCA A;  4FJQ A;  3BNY A;  1JFA A;  1N22 A;  2Z4Y A;  5AYP A;  1ZW5 A;  2QIS A;  4KQ5 A;  2OA6 A;  3WEI A;  2ZEU A;  5DJV F;  3IPI A;  5A0K A;  3V66 A;  4GAX A;  4KQU A;  4DI5 A;  5ILY A;  1DGP A;  3SAE A;  5HN9 A;  3VJ8 A;  1YV5 A;  1WMW A;  1VG7 A;  3N49 F;  5DJP F;  2E92 A;  2ZEV A;  5IN8 A;  3V1V A;  3M9U A;  4H5C F;  2FTZ A;  4KFA A;  3ICM A;  3VJC A;  2E93 A;  3APZ A;  4LA5 A;  3WEF A;  3N46 F;  3EZ3 A;  1HM4 A;  4JYX A;  2EWG A;  2F8C F;  3RYE A;  3ADZ A;  2E8T A;  1V4H A;  1YYT A;  5DJR F;  1YJ4 A;  4WK5 A;  3N45 F;  3WCC A;  2Z7H A;  2H8O A;  2F9K F;  4K10 A;  2Z7I A;  1N23 A;  1YYS A;  3NPK A;  3MAV A;  3WCM A;  4EA0 A;  1N24 A;  1UBW A;  5IMI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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