2FAPA

The structure of the immunophilin-immunosuppressant fkbp12-(c16)-ethoxy rapamycin complex interacting with huma
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
107
structure length
107
Chain Sequence
GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution.
pubmed doi rcsb
molecule keywords FK506-BINDING PROTEIN
molecule tags Complex (isomerase/kinase)
source organism Homo sapiens
total genus 25
structure length 107
sequence length 107
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 1998-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00254 FKBP_C FKBP-type peptidyl-prolyl cis-trans isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.50.40 Alpha Beta Roll Chitinase A; domain 3 Chitinase A; domain 3 2fapA00
3CGMA 4W9PA 2XPBA 4QIBA 3O5QA 4ODMA 4MGVA 4JYSA 2RUDA 4JFIA 2ZR5A 1QPFA 4O2TA 4U86A 2LJ4A 3KAHA 4ODRA 1EYMA 4BF8A 4DZ3A 4GGQA 5HT1A 4TW6A 3KZ7A 1BKFA 2VCDA 2ZQSA 3UQAA 1FKKA 1FKDA 3NRKA 1ROUA 2MNTA 1W26A 4IPXA 3KADA 5DITA 4LAXA 2ZQTA 5HW8A 5HW7A 1D7IA 1P5QA 3PA7A 5B8IC 5HWBA 1FAPA 2ZQUA 2ITKA 3IK8A 4N19A 4NNRA 5D75A 4DRQA 3UI5A 1FKRA 3WH0A 3H9RB 1J4RA 4JFLA 2PV3A 5J6EA 1A7XA 5HUAA 2MPHA 4ODQA 4ITZA 3TDBA 1HXVA 1Q6HA 4DRHA 2K8IA 5GPGA 1FKTA 2KGJA 1ZK6A 1QPLA 3JXVA 3KACA 3PRDA 4LAVA 2F4EA 3TCZA 1D7HA 2KI3A 4FN2A 3RFWA 2RUQA 4IQCA 1M5YA 2DG3A 2KFWA 2DG9A 3KCEA 3O5JA 1FKBA 1KT0A 1B6CA 1NMWA 1FKGA 3JYMA 4G50A 5BXJA 1L1PA 3CGNA 2OFNA 4TW7A 1PBKA 2M2AA 4ODKA 4ODNA 3VAWA 2M1IA 3IHZA 4U84A 1KT1A 2RSEA 2Y78A 3I6CA 3O5KA 2FAPA 4DIPA 3RGCA 1R9HA 2IF4A 4IQ2A 4J4OA 2F21A 1JNTA 2KR7A 2F2DA 2MLYA 1FKIA 4G2PA 4ODOA 3FAPA 1J6YA 1J4IA 4LAWA 1T11A 2KO7A 2PBCA 2PPNA 1JVWA 1FKHA 2KE0A 2Q5AA 4TX0A 2PPOA 4DRPA 1Q6UA 2MF9A 2XP5A 2M08A 1YW5A 1D6OA 3O5GA 3O5LA 1FD9A 1ROTA 4TYOA 2ZR4A 4W9OA 1N1AA 2MLXA 2ZR6A 4TW8A 2XP9A 2XP8A 2LKNA 3KAGA 4FAPA 4DRMA 3KABA 2XP3A 3O5PA 4LAYA 2RQSA 3B7XA 2XPAA 2XP6A 3TC5A 2AWGA 4TNSA 3ODKA 4DH0A 4DRNA 3JYJA 3O5RA 3KAFA 3LUOA 1FKJA 1Q6IA 2VN1A 4DT4A 3O5DA 1NSGA 1ZCNA 2RURA 1U79A 3UI6A 3MDYB 4DROA 3O5IA 4JFJA 2PV1A 1Q1CA 3UI4A 5HWCA 1FJDA 3OOBA 2PPPA 1FKLA 5DIUA 2UZ5A 3GPKA 3NTPA 1EQ3A 2FKEA 2MLZA 4R0XA 5I98A 3IKGA 1FKSA 4QT2A 3O5MA 3UQIA 1Y0OA 3O5OA 1NMVA 5DIVA 1JNSA 2N87A 4JFKA 4GIVA 1TCOC 4J4NA 1QZ2A 2XP4A 3KAIA 2PV2A 5HKGA 1D7JA 2JZVA 2RUCA 3UQBA 2DG4A 4DRKA 3EY6A 4QT3A 1BL4A 3O5FA 3PRBA 2D9FA 3NI6A 3O5EA 2ZQVA 4U85A 1F8AB 1FKFA 1PINA 2LPVA 3UF8A 4DRJA 4JFMA 1J4HA 4MSPA 2L2SA 1F40A 4DRIA 1C9HA 3IKDA 4ODPA 2XP7A 5HTGA 4DZ2A 4ODLA 1YATA 2LGOA 4W9QA 5HW6A 4C02B
chains in the Genus database with same CATH superfamily
2XPBA 1GUVA 4JYSA 4BF8A 2YBTA 4U86A 3KAHA 1EYMA 5HT1A 4L72B 1ROUA 3KADA 5HW8A 5DEZA 5B8IC 3GTYX 2ZQUA 4NNRA 5D75A 1HKIA 4S3KA 4ODQA 4QZVB 1NWUA 3JXVA 1D2KA 2DSZA 4Z2IA 4MAVA 4G50A 1B6CA 3AS0A 4ODNA 4ODKA 3VAWA 3IHZA 1HKKA 1KT1A 3I6CA 1JNTA 1W9VA 1T11A 4L3NA 1ZL1A 3WQVA 1FKHA 2KE0A 2PPOA 1SYTA 3ARRA 2MF9A 4LGXA 1YW5A 1D6OA 3WKZA 1N1AA 1ZB5A 2XP8A 4FAPA 2IUZA 3O5PA 2RQSA 2XP6A 3JYJA 1HJWA 3KAFA 1Q6IA 2VN1A 3O5DA 1EDQA 3MDYB 2PV1A 3CZ8A 1JNDA 2DSWA 3GPKA 3NTPA 1EQ3A 3IKGA 5DIVA 1JNSA 2N87A 4GIVA 1QZ2A 5HKGA 3KAIA 2PV2A 1HKMA 4IT6A 1EIBA 2DG4A 4DRKA 2DPEA 3ARTA 3EY6A 4KQZA 4MNMA 1E6PA 4U85A 3NI6A 5JH8A 2ZQVA 1PINA 4Z2HA 4JFMA 1J4HA 2L2SA 4DRIA 1XRVA 3IKDA 5HTGA 2QF8A 4Q7NA 4WIWA 4XAKA 4W9QA 1O6IA 3CGMA 4W9PA 4ODMA 4MGVA 2RUDA 4O2TA 1XHGA 1BKFA 2ZQSA 3UQAA 1FKDA 2PI6A 2MNTA 5HBFA 4LAXA 5HWBA 1P5QA 2ITKA 1HJVA 3IK8A 3WD2A 2WK2A 1IX5A 2B5UB 1HJXA 1FKRA 3H9RB 2WLYA 4JFLA 1NWTA 2PV3A 4WKAA 2MPHA 5DO2A 3TDBA 4DRHA 1GOIA 1FKTA 3KACA 1QPLA 4LAVA 2F4EA 4FN2A 2RUQA 4IQCA 1GPFA 3ARPA 2DG3A 3CH9A 2DSVA 3BMBA 2OFNA 2M2AA 3G6LA 2M1IA 4U84A 2RSEA 4DIPA 2B31A 4IQ2A 3B8SA 2MLYA 1FKIA 4ML4A 3ARZA 1J4IA 1J6YA 3AQUA 2PPNA 4TX0A 3CHCA 4DWSD 2XP5A 2M08A 1RD6A 1W1PA 2ZR4A 2MLXA 4TW8A 2XP9A 1H0GA 1VF8A 1UR8A 4MNLA 1CTNA 4MNJA 4LAYA 3RM9A 4UDMA 3TC5A 4DRNA 4DH0A 3WD4A 1E6RA 3W4RA 3B9DA 1FFQA 1NSGA 4DROA 3ARUA 5HWCA 3ALFA 1LL4A 1ZBVA 2DT2A 3CHDA 2MLZA 4R0XA 5I98A 1FKSA 3O5MA 4ZPVR 3ARWA 1Y0OA 1ZU8A 1LJYA 1KFWA 1LL7A 1D7JA 2JZVA 5GPRA 4MPKA 3O5FA 3PRBA 1E44A 3O5EA 1FKFA 4R5EA 3WD1A 4DWSA 5DF0A 1W1TA 1WAWA 5HW6A 4QIBA 1SR0A 5GQBA 4KR0B 1W1YA 2ZR5A 2FDMA 4ODRA 4IT4A 4DZ3A 4TW6A 3AROA 1GRJA 3NRKA 4ZPTR 2ZQTA 3PA7A 1K9TA 3ARYA 4N19A 4DRQA 1FFRA 2YBUA 3UI5A 2A3CA 3WH0A 1LG2A 4DWSC 1A7XA 4ITZA 1HXVA 2K8IA 3B9EA 4NSBA 5GPGA 3PRDA 3TCZA 3RFWA 4MTVA 3AS1A 1M5YA 1OGBA 2KFWA 3O5JA 4PTMA 1FKBA 1NMWA 1FKGA 5BXJA 2PN0A 4TW7A 1PBKA 2A3EA 2Y78A 2FAPA 3RGCA 1R9HA 4NZCA 2F21A 2KR7A 3ALGA 2F23A 4G2PA 4ODOA 3FAPA 4WKFA 4LAWA 1E15A 3ARXA 2PBCA 4DRPA 2A3BA 2O92A 1ZBCA 3O5LA 2ZR6A 1E9LA 4MNKA 1EHNA 3B7XA 2AWGA 1OGGA 1LQ0A 3O5RA 3LUOA 3GU0A 1FKJA 2DT0A 2DT3A 2DSUA 4DT4A 3AS2A 2A3AA 1U79A 1ITXA 3UI6A 2DT1A 3UI4A 1Q1CA 3RM8A 1UR9A 1FKLA 2UZ5A 2WLZA 4S3JA 2FKEA 2ETNA 4P8VA 4QT2A 3O5OA 1NMVA 1NWRA 4JFKA 1WB0A 1TCOC 4DWSB 4ZPWR 3RM4A 2RUCA 1H0IA 4Z2JA 4P8WA 3UQBA 4P8XA 3G6MA 3WD3A 1BL4A 2WM0A 4DRJA 4MSPA 4Z2GA 3CHEA 1C9HA 4ODPA 2XP7A 3PRAA 4DZ2A 4ODLA 2LGOA 4C02B 1E6ZA 3CHFA 2G41A 3O5QA 4WK9A 4JFIA 2P4VA 1QPFA 4GGQA 1TFVA 3ARSA 3KZ7A 2VCDA 3WL1A 1FKKA 5DITA 1W26A 4IPXA 5HW7A 1D7IA 1FAPA 3QOKA 3B9AA 1J4RA 4Z2KA 3PR9A 5J6EA 5HUAA 3WQWA 4WKHA 1X6NA 1Q6HA 4Q22A 1ZBKA 2KGJA 1ZK6A 3WL0A 1D7HA 2KI3A 1WNOA 2DG9A 3KCEA 3FXYA 1KT0A 3JYMA 1L1PA 4HBEA 3AS3A 3CGNA 1NH6A 1W1VA 4HBOA 3WIJA 3O5KA 2O9OA 2IF4A 3BXWA 4J4OA 4W5UA 3EIPA 2F2DA 2KO7A 2OLHA 3WD0A 3FY1A 1JVWA 2Q5AA 1JCHB 1Q6UA 4WJXA 1W9PA 1ZBWA 3O5GA 1FD9A 1ROTA 4TYOA 4W9OA 2LKNA 3KAGA 4DRMA 3KABA 2XP3A 2XPAA 4AY1A 4TNSA 4Z2LA 3ODKA 3OA5A 2AOSA 1ZCNA 1E6NA 2RURA 1LL6A 1LG1A 1W9UA 3O5IA 4JFJA 1X6LA 2G8ZA 3OOBA 2PPPA 5DIUA 3ARVA 2EULA 4P8UA 3UQIA 1HKJA 3RMEA 4J4NA 1JNEA 2XP4A 1NWSA 2ESCA 4HARA 4ZS6A 4QT3A 4URIA 2D9FA 1F8AB 3ARQA 3UF8A 2LPVA 1OWQA 1F40A 1YATA 2LJ4A 1FJDA
chains in the Genus database with same CATH topology
2XPBA 1GUVA 4JYSA 4BF8A 2YBTA 4U86A 3KAHA 1EYMA 5HT1A 4L72B 1ROUA 3KADA 5HW8A 5DEZA 5B8IC 2ZQUA 4NNRA 5D75A 1HKIA 4S3KA 4ODQA 4QZVB 1NWUA 3JXVA 1D2KA 2DSZA 4Z2IA 4MAVA 4G50A 1B6CA 3AS0A 4ODNA 4ODKA 3VAWA 3IHZA 1HKKA 1KT1A 3I6CA 1JNTA 1W9VA 1T11A 4L3NA 1ZL1A 3WQVA 1FKHA 2KE0A 2PPOA 1SYTA 3ARRA 2MF9A 4LGXA 1YW5A 1D6OA 3WKZA 1N1AA 1ZB5A 2XP8A 4FAPA 2IUZA 3O5PA 2RQSA 2XP6A 3JYJA 1HJWA 3KAFA 1Q6IA 2VN1A 3O5DA 1EDQA 3MDYB 2PV1A 3CZ8A 1JNDA 2DSWA 3GPKA 3NTPA 1EQ3A 3IKGA 5DIVA 1JNSA 2N87A 4GIVA 1QZ2A 5HKGA 3KAIA 2PV2A 1HKMA 4IT6A 1EIBA 2DG4A 4DRKA 2DPEA 3ARTA 3EY6A 4KQZA 4MNMA 1E6PA 4U85A 3NI6A 5JH8A 2ZQVA 1PINA 4Z2HA 4JFMA 1J4HA 2L2SA 4DRIA 1XRVA 3IKDA 5HTGA 2QF8A 4Q7NA 4WIWA 4XAKA 4W9QA 1O6IA 3CGMA 4W9PA 4ODMA 4MGVA 2RUDA 4O2TA 1XHGA 1BKFA 2ZQSA 3UQAA 1FKDA 2PI6A 2MNTA 5HBFA 4LAXA 5HWBA 1P5QA 2ITKA 1HJVA 3IK8A 3WD2A 2WK2A 1IX5A 1HJXA 1FKRA 3H9RB 2WLYA 4JFLA 1NWTA 2PV3A 4WKAA 2MPHA 5DO2A 3TDBA 4DRHA 1GOIA 1FKTA 3KACA 1QPLA 4LAVA 2F4EA 4FN2A 2RUQA 4IQCA 1GPFA 3ARPA 2DG3A 3CH9A 2DSVA 2OFNA 2M2AA 3G6LA 2M1IA 4U84A 2RSEA 4DIPA 2B31A 4IQ2A 3B8SA 2MLYA 1FKIA 4ML4A 3ARZA 1J4IA 1J6YA 3AQUA 2PPNA 4TX0A 3CHCA 4DWSD 2XP5A 2M08A 1RD6A 1W1PA 2ZR4A 2MLXA 4TW8A 2XP9A 1H0GA 1VF8A 1UR8A 4MNLA 1CTNA 4MNJA 4LAYA 3RM9A 3TC5A 4DRNA 4DH0A 3WD4A 1E6RA 3W4RA 3B9DA 1FFQA 1NSGA 4DROA 3ARUA 5HWCA 3ALFA 1LL4A 1ZBVA 2DT2A 3CHDA 2MLZA 4R0XA 5I98A 1FKSA 3O5MA 4ZPVR 3ARWA 1Y0OA 1ZU8A 1LJYA 1KFWA 1LL7A 1D7JA 2JZVA 5GPRA 4MPKA 3O5FA 3PRBA 3O5EA 1FKFA 4R5EA 3WD1A 4DWSA 5DF0A 1W1TA 1WAWA 5HW6A 4QIBA 1SR0A 5GQBA 4KR0B 1W1YA 2ZR5A 2FDMA 4ODRA 4IT4A 4DZ3A 4TW6A 3AROA 3NRKA 4ZPTR 2ZQTA 3PA7A 1K9TA 3ARYA 4N19A 4DRQA 1FFRA 2YBUA 3UI5A 2A3CA 3WH0A 1LG2A 4DWSC 1A7XA 4ITZA 1HXVA 2K8IA 3B9EA 4NSBA 5GPGA 3PRDA 3TCZA 3RFWA 4MTVA 3AS1A 1M5YA 1OGBA 2KFWA 3O5JA 4PTMA 1FKBA 1NMWA 1FKGA 5BXJA 4TW7A 1PBKA 2A3EA 2Y78A 2FAPA 3RGCA 1R9HA 4NZCA 2F21A 2KR7A 3ALGA 4G2PA 4ODOA 3FAPA 4WKFA 4LAWA 1E15A 3ARXA 2PBCA 4DRPA 2A3BA 2O92A 1ZBCA 3O5LA 2ZR6A 1E9LA 4MNKA 1EHNA 3B7XA 2AWGA 1OGGA 1LQ0A 3O5RA 3LUOA 1FKJA 2DT0A 2DT3A 2DSUA 4DT4A 3AS2A 2A3AA 1U79A 1ITXA 3UI6A 2DT1A 3UI4A 1Q1CA 3RM8A 1UR9A 1FKLA 2UZ5A 2WLZA 4S3JA 2FKEA 4P8VA 4QT2A 3O5OA 1NMVA 1NWRA 4JFKA 1WB0A 1TCOC 4DWSB 4ZPWR 3RM4A 2RUCA 1H0IA 4Z2JA 4P8WA 3UQBA 4P8XA 3G6MA 3WD3A 1BL4A 2WM0A 4DRJA 4MSPA 4Z2GA 3CHEA 1C9HA 4ODPA 2XP7A 3PRAA 4DZ2A 4ODLA 2LGOA 4C02B 1E6ZA 3CHFA 2G41A 3O5QA 4WK9A 4JFIA 1QPFA 4GGQA 1TFVA 3ARSA 3KZ7A 2VCDA 3WL1A 1FKKA 5DITA 1W26A 4IPXA 5HW7A 1D7IA 1FAPA 3QOKA 3B9AA 1J4RA 4Z2KA 3PR9A 5J6EA 5HUAA 3WQWA 4WKHA 1X6NA 1Q6HA 4Q22A 1ZBKA 2KGJA 1ZK6A 3WL0A 1D7HA 2KI3A 1WNOA 2DG9A 3KCEA 3FXYA 1KT0A 3JYMA 1L1PA 4HBEA 3AS3A 3CGNA 1NH6A 1W1VA 4HBOA 3WIJA 3O5KA 2O9OA 2IF4A 3BXWA 4J4OA 4W5UA 2F2DA 2KO7A 2OLHA 3WD0A 3FY1A 1JVWA 2Q5AA 1Q6UA 4WJXA 1W9PA 1ZBWA 3O5GA 1FD9A 1ROTA 4TYOA 4W9OA 2LKNA 3KAGA 4DRMA 3KABA 2XP3A 2XPAA 4AY1A 4TNSA 4Z2LA 3ODKA 3OA5A 2AOSA 1ZCNA 1E6NA 2RURA 1LL6A 1LG1A 1W9UA 3O5IA 4JFJA 1X6LA 2G8ZA 3OOBA 2PPPA 5DIUA 3ARVA 4P8UA 3UQIA 1HKJA 3RMEA 4J4NA 1JNEA 2XP4A 1NWSA 2ESCA 4HARA 4ZS6A 4QT3A 4URIA 2D9FA 1F8AB 3ARQA 3UF8A 2LPVA 1OWQA 1F40A 1YATA 2LJ4A 1FJDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CGM A;  4W9P A;  2XPB A;  4QIB A;  3O5Q A;  4ODM A;  4MGV A;  4JYS A;  2RUD A;  4JFI A;  2ZR5 A;  1QPF A;  4O2T A;  4U86 A;  2LJ4 A;  3KAH A;  4ODR A;  1EYM A;  4BF8 A;  4DZ3 A;  4GGQ A;  5HT1 A;  4TW6 A;  3KZ7 A;  1BKF A;  2VCD A;  2ZQS A;  3UQA A;  1FKK A;  1FKD A;  3NRK A;  1ROU A;  2MNT A;  1W26 A;  4IPX A;  3KAD A;  5DIT A;  4LAX A;  2ZQT A;  5HW8 A;  5HW7 A;  1D7I A;  1P5Q A;  3PA7 A;  5B8I C;  5HWB A;  1FAP A;  2ZQU A;  2ITK A;  3IK8 A;  4N19 A;  4NNR A;  5D75 A;  4DRQ A;  3UI5 A;  1FKR A;  3WH0 A;  3H9R B;  1J4R A;  4JFL A;  2PV3 A;  5J6E A;  1A7X A;  5HUA A;  2MPH A;  4ODQ A;  4ITZ A;  3TDB A;  1HXV A;  1Q6H A;  4DRH A;  2K8I A;  5GPG A;  1FKT A;  2KGJ A;  1ZK6 A;  1QPL A;  3JXV A;  3KAC A;  3PRD A;  4LAV A;  2F4E A;  3TCZ A;  1D7H A;  2KI3 A;  4FN2 A;  3RFW A;  2RUQ A;  4IQC A;  1M5Y A;  2DG3 A;  2KFW A;  2DG9 A;  3KCE A;  3O5J A;  1FKB A;  1KT0 A;  1B6C A;  1NMW A;  1FKG A;  3JYM A;  4G50 A;  5BXJ A;  1L1P A;  3CGN A;  2OFN A;  4TW7 A;  1PBK A;  2M2A A;  4ODK A;  4ODN A;  3VAW A;  2M1I A;  3IHZ A;  4U84 A;  1KT1 A;  2RSE A;  2Y78 A;  3I6C A;  3O5K A;  2FAP A;  4DIP A;  3RGC A;  1R9H A;  2IF4 A;  4IQ2 A;  4J4O A;  2F21 A;  1JNT A;  2KR7 A;  2F2D A;  2MLY A;  1FKI A;  4G2P A;  4ODO A;  3FAP A;  1J6Y A;  1J4I A;  4LAW A;  1T11 A;  2KO7 A;  2PBC A;  2PPN A;  1JVW A;  1FKH A;  2KE0 A;  2Q5A A;  4TX0 A;  2PPO A;  4DRP A;  1Q6U A;  2MF9 A;  2XP5 A;  2M08 A;  1YW5 A;  1D6O A;  3O5G A;  3O5L A;  1FD9 A;  1ROT A;  4TYO A;  2ZR4 A;  4W9O A;  1N1A A;  2MLX A;  2ZR6 A;  4TW8 A;  2XP9 A;  2XP8 A;  2LKN A;  3KAG A;  4FAP A;  4DRM A;  3KAB A;  2XP3 A;  3O5P A;  4LAY A;  2RQS A;  3B7X A;  2XPA A;  2XP6 A;  3TC5 A;  2AWG A;  4TNS A;  3ODK A;  4DH0 A;  4DRN A;  3JYJ A;  3O5R A;  3KAF A;  3LUO A;  1FKJ A;  1Q6I A;  2VN1 A;  4DT4 A;  3O5D A;  1NSG A;  1ZCN A;  2RUR A;  1U79 A;  3UI6 A;  3MDY B;  4DRO A;  3O5I A;  4JFJ A;  2PV1 A;  1Q1C A;  3UI4 A;  5HWC A;  1FJD A;  3OOB A;  2PPP A;  1FKL A;  5DIU A;  2UZ5 A;  3GPK A;  3NTP A;  1EQ3 A;  2FKE A;  2MLZ A;  4R0X A;  5I98 A;  3IKG A;  1FKS A;  4QT2 A;  3O5M A;  3UQI A;  1Y0O A;  3O5O A;  1NMV A;  5DIV A;  1JNS A;  2N87 A;  4JFK A;  4GIV A;  1TCO C;  4J4N A;  1QZ2 A;  2XP4 A;  3KAI A;  2PV2 A;  5HKG A;  1D7J A;  2JZV A;  2RUC A;  3UQB A;  2DG4 A;  4DRK A;  3EY6 A;  4QT3 A;  1BL4 A;  3O5F A;  3PRB A;  2D9F A;  3NI6 A;  3O5E A;  2ZQV A;  4U85 A;  1F8A B;  1FKF A;  1PIN A;  2LPV A;  3UF8 A;  4DRJ A;  4JFM A;  1J4H A;  4MSP A;  2L2S A;  1F40 A;  4DRI A;  1C9H A;  3IKD A;  4ODP A;  2XP7 A;  5HTG A;  4DZ2 A;  4ODL A;  1YAT A;  2LGO A;  4W9Q A;  5HW6 A;  4C02 B; 
#chains in the Genus database with same CATH topology
 2XPB A;  1GUV A;  4JYS A;  4BF8 A;  2YBT A;  4U86 A;  3KAH A;  1EYM A;  5HT1 A;  4L72 B;  1ROU A;  3KAD A;  5HW8 A;  5DEZ A;  5B8I C;  3GTY X;  2ZQU A;  4NNR A;  5D75 A;  1HKI A;  4S3K A;  4ODQ A;  4QZV B;  1NWU A;  3JXV A;  1D2K A;  2DSZ A;  4Z2I A;  4MAV A;  4G50 A;  1B6C A;  3AS0 A;  4ODN A;  4ODK A;  3VAW A;  3IHZ A;  1HKK A;  1KT1 A;  3I6C A;  1JNT A;  1W9V A;  1T11 A;  4L3N A;  1ZL1 A;  3WQV A;  1FKH A;  2KE0 A;  2PPO A;  1SYT A;  3ARR A;  2MF9 A;  4LGX A;  1YW5 A;  1D6O A;  3WKZ A;  1N1A A;  1ZB5 A;  2XP8 A;  4FAP A;  2IUZ A;  3O5P A;  2RQS A;  2XP6 A;  3JYJ A;  1HJW A;  3KAF A;  1Q6I A;  2VN1 A;  3O5D A;  1EDQ A;  3MDY B;  2PV1 A;  3CZ8 A;  1JND A;  2DSW A;  3GPK A;  3NTP A;  1EQ3 A;  3IKG A;  5DIV A;  1JNS A;  2N87 A;  4GIV A;  1QZ2 A;  5HKG A;  3KAI A;  2PV2 A;  1HKM A;  4IT6 A;  1EIB A;  2DG4 A;  4DRK A;  2DPE A;  3ART A;  3EY6 A;  4KQZ A;  4MNM A;  1E6P A;  4U85 A;  3NI6 A;  5JH8 A;  2ZQV A;  1PIN A;  4Z2H A;  4JFM A;  1J4H A;  2L2S A;  4DRI A;  1XRV A;  3IKD A;  5HTG A;  2QF8 A;  4Q7N A;  4WIW A;  4XAK A;  4W9Q A;  1O6I A;  3CGM A;  4W9P A;  4ODM A;  4MGV A;  2RUD A;  4O2T A;  1XHG A;  1BKF A;  2ZQS A;  3UQA A;  1FKD A;  2PI6 A;  2MNT A;  5HBF A;  4LAX A;  5HWB A;  1P5Q A;  2ITK A;  1HJV A;  3IK8 A;  3WD2 A;  2WK2 A;  1IX5 A;  2B5U B;  1HJX A;  1FKR A;  3H9R B;  2WLY A;  4JFL A;  1NWT A;  2PV3 A;  4WKA A;  2MPH A;  5DO2 A;  3TDB A;  4DRH A;  1GOI A;  1FKT A;  3KAC A;  1QPL A;  4LAV A;  2F4E A;  4FN2 A;  2RUQ A;  4IQC A;  1GPF A;  3ARP A;  2DG3 A;  3CH9 A;  2DSV A;  3BMB A;  2OFN A;  2M2A A;  3G6L A;  2M1I A;  4U84 A;  2RSE A;  4DIP A;  2B31 A;  4IQ2 A;  3B8S A;  2MLY A;  1FKI A;  4ML4 A;  3ARZ A;  1J4I A;  1J6Y A;  3AQU A;  2PPN A;  4TX0 A;  3CHC A;  4DWS D;  2XP5 A;  2M08 A;  1RD6 A;  1W1P A;  2ZR4 A;  2MLX A;  4TW8 A;  2XP9 A;  1H0G A;  1VF8 A;  1UR8 A;  4MNL A;  1CTN A;  4MNJ A;  4LAY A;  3RM9 A;  4UDM A;  3TC5 A;  4DRN A;  4DH0 A;  3WD4 A;  1E6R A;  3W4R A;  3B9D A;  1FFQ A;  1NSG A;  4DRO A;  3ARU A;  5HWC A;  3ALF A;  1LL4 A;  1ZBV A;  2DT2 A;  3CHD A;  2MLZ A;  4R0X A;  5I98 A;  1FKS A;  3O5M A;  4ZPV R;  3ARW A;  1Y0O A;  1ZU8 A;  1LJY A;  1KFW A;  1LL7 A;  1D7J A;  2JZV A;  5GPR A;  4MPK A;  3O5F A;  3PRB A;  1E44 A;  3O5E A;  1FKF A;  4R5E A;  3WD1 A;  4DWS A;  5DF0 A;  1W1T A;  1WAW A;  5HW6 A;  4QIB A;  1SR0 A;  5GQB A;  4KR0 B;  1W1Y A;  2ZR5 A;  2FDM A;  4ODR A;  4IT4 A;  4DZ3 A;  4TW6 A;  3ARO A;  1GRJ A;  3NRK A;  4ZPT R;  2ZQT A;  3PA7 A;  1K9T A;  3ARY A;  4N19 A;  4DRQ A;  1FFR A;  2YBU A;  3UI5 A;  2A3C A;  3WH0 A;  1LG2 A;  4DWS C;  1A7X A;  4ITZ A;  1HXV A;  2K8I A;  3B9E A;  4NSB A;  5GPG A;  3PRD A;  3TCZ A;  3RFW A;  4MTV A;  3AS1 A;  1M5Y A;  1OGB A;  2KFW A;  3O5J A;  4PTM A;  1FKB A;  1NMW A;  1FKG A;  5BXJ A;  2PN0 A;  4TW7 A;  1PBK A;  2A3E A;  2Y78 A;  2FAP A;  3RGC A;  1R9H A;  4NZC A;  2F21 A;  2KR7 A;  3ALG A;  2F23 A;  4G2P A;  4ODO A;  3FAP A;  4WKF A;  4LAW A;  1E15 A;  3ARX A;  2PBC A;  4DRP A;  2A3B A;  2O92 A;  1ZBC A;  3O5L A;  2ZR6 A;  1E9L A;  4MNK A;  1EHN A;  3B7X A;  2AWG A;  1OGG A;  1LQ0 A;  3O5R A;  3LUO A;  3GU0 A;  1FKJ A;  2DT0 A;  2DT3 A;  2DSU A;  4DT4 A;  3AS2 A;  2A3A A;  1U79 A;  1ITX A;  3UI6 A;  2DT1 A;  3UI4 A;  1Q1C A;  3RM8 A;  1UR9 A;  1FKL A;  2UZ5 A;  2WLZ A;  4S3J A;  2FKE A;  2ETN A;  4P8V A;  4QT2 A;  3O5O A;  1NMV A;  1NWR A;  4JFK A;  1WB0 A;  1TCO C;  4DWS B;  4ZPW R;  3RM4 A;  2RUC A;  1H0I A;  4Z2J A;  4P8W A;  3UQB A;  4P8X A;  3G6M A;  3WD3 A;  1BL4 A;  2WM0 A;  4DRJ A;  4MSP A;  4Z2G A;  3CHE A;  1C9H A;  4ODP A;  2XP7 A;  3PRA A;  4DZ2 A;  4ODL A;  2LGO A;  4C02 B;  1E6Z A;  3CHF A;  2G41 A;  3O5Q A;  4WK9 A;  4JFI A;  2P4V A;  1QPF A;  4GGQ A;  1TFV A;  3ARS A;  3KZ7 A;  2VCD A;  3WL1 A;  1FKK A;  5DIT A;  1W26 A;  4IPX A;  5HW7 A;  1D7I A;  1FAP A;  3QOK A;  3B9A A;  1J4R A;  4Z2K A;  3PR9 A;  5J6E A;  5HUA A;  3WQW A;  4WKH A;  1X6N A;  1Q6H A;  4Q22 A;  1ZBK A;  2KGJ A;  1ZK6 A;  3WL0 A;  1D7H A;  2KI3 A;  1WNO A;  2DG9 A;  3KCE A;  3FXY A;  1KT0 A;  3JYM A;  1L1P A;  4HBE A;  3AS3 A;  3CGN A;  1NH6 A;  1W1V A;  4HBO A;  3WIJ A;  3O5K A;  2O9O A;  2IF4 A;  3BXW A;  4J4O A;  4W5U A;  3EIP A;  2F2D A;  2KO7 A;  2OLH A;  3WD0 A;  3FY1 A;  1JVW A;  2Q5A A;  1JCH B;  1Q6U A;  4WJX A;  1W9P A;  1ZBW A;  3O5G A;  1FD9 A;  1ROT A;  4TYO A;  4W9O A;  2LKN A;  3KAG A;  4DRM A;  3KAB A;  2XP3 A;  2XPA A;  4AY1 A;  4TNS A;  4Z2L A;  3ODK A;  3OA5 A;  2AOS A;  1ZCN A;  1E6N A;  2RUR A;  1LL6 A;  1LG1 A;  1W9U A;  3O5I A;  4JFJ A;  1X6L A;  2G8Z A;  3OOB A;  2PPP A;  5DIU A;  3ARV A;  2EUL A;  4P8U A;  3UQI A;  1HKJ A;  3RME A;  4J4N A;  1JNE A;  2XP4 A;  1NWS A;  2ESC A;  4HAR A;  4ZS6 A;  4QT3 A;  4URI A;  2D9F A;  1F8A B;  3ARQ A;  3UF8 A;  2LPV A;  1OWQ A;  1F40 A;  1YAT A;  2LJ4 A;  1FJD A; 
#chains in the Genus database with same CATH homology
 2XPB A;  1GUV A;  4JYS A;  4BF8 A;  2YBT A;  4U86 A;  3KAH A;  1EYM A;  5HT1 A;  4L72 B;  1ROU A;  3KAD A;  5HW8 A;  5DEZ A;  5B8I C;  2ZQU A;  4NNR A;  5D75 A;  1HKI A;  4S3K A;  4ODQ A;  4QZV B;  1NWU A;  3JXV A;  1D2K A;  2DSZ A;  4Z2I A;  4MAV A;  4G50 A;  1B6C A;  3AS0 A;  4ODN A;  4ODK A;  3VAW A;  3IHZ A;  1HKK A;  1KT1 A;  3I6C A;  1JNT A;  1W9V A;  1T11 A;  4L3N A;  1ZL1 A;  3WQV A;  1FKH A;  2KE0 A;  2PPO A;  1SYT A;  3ARR A;  2MF9 A;  4LGX A;  1YW5 A;  1D6O A;  3WKZ A;  1N1A A;  1ZB5 A;  2XP8 A;  4FAP A;  2IUZ A;  3O5P A;  2RQS A;  2XP6 A;  3JYJ A;  1HJW A;  3KAF A;  1Q6I A;  2VN1 A;  3O5D A;  1EDQ A;  3MDY B;  2PV1 A;  3CZ8 A;  1JND A;  2DSW A;  3GPK A;  3NTP A;  1EQ3 A;  3IKG A;  5DIV A;  1JNS A;  2N87 A;  4GIV A;  1QZ2 A;  5HKG A;  3KAI A;  2PV2 A;  1HKM A;  4IT6 A;  1EIB A;  2DG4 A;  4DRK A;  2DPE A;  3ART A;  3EY6 A;  4KQZ A;  4MNM A;  1E6P A;  4U85 A;  3NI6 A;  5JH8 A;  2ZQV A;  1PIN A;  4Z2H A;  4JFM A;  1J4H A;  2L2S A;  4DRI A;  1XRV A;  3IKD A;  5HTG A;  2QF8 A;  4Q7N A;  4WIW A;  4XAK A;  4W9Q A;  1O6I A;  3CGM A;  4W9P A;  4ODM A;  4MGV A;  2RUD A;  4O2T A;  1XHG A;  1BKF A;  2ZQS A;  3UQA A;  1FKD A;  2PI6 A;  2MNT A;  5HBF A;  4LAX A;  5HWB A;  1P5Q A;  2ITK A;  1HJV A;  3IK8 A;  3WD2 A;  2WK2 A;  1IX5 A;  1HJX A;  1FKR A;  3H9R B;  2WLY A;  4JFL A;  1NWT A;  2PV3 A;  4WKA A;  2MPH A;  5DO2 A;  3TDB A;  4DRH A;  1GOI A;  1FKT A;  3KAC A;  1QPL A;  4LAV A;  2F4E A;  4FN2 A;  2RUQ A;  4IQC A;  1GPF A;  3ARP A;  2DG3 A;  3CH9 A;  2DSV A;  2OFN A;  2M2A A;  3G6L A;  2M1I A;  4U84 A;  2RSE A;  4DIP A;  2B31 A;  4IQ2 A;  3B8S A;  2MLY A;  1FKI A;  4ML4 A;  3ARZ A;  1J4I A;  1J6Y A;  3AQU A;  2PPN A;  4TX0 A;  3CHC A;  4DWS D;  2XP5 A;  2M08 A;  1RD6 A;  1W1P A;  2ZR4 A;  2MLX A;  4TW8 A;  2XP9 A;  1H0G A;  1VF8 A;  1UR8 A;  4MNL A;  1CTN A;  4MNJ A;  4LAY A;  3RM9 A;  3TC5 A;  4DRN A;  4DH0 A;  3WD4 A;  1E6R A;  3W4R A;  3B9D A;  1FFQ A;  1NSG A;  4DRO A;  3ARU A;  5HWC A;  3ALF A;  1LL4 A;  1ZBV A;  2DT2 A;  3CHD A;  2MLZ A;  4R0X A;  5I98 A;  1FKS A;  3O5M A;  4ZPV R;  3ARW A;  1Y0O A;  1ZU8 A;  1LJY A;  1KFW A;  1LL7 A;  1D7J A;  2JZV A;  5GPR A;  4MPK A;  3O5F A;  3PRB A;  3O5E A;  1FKF A;  4R5E A;  3WD1 A;  4DWS A;  5DF0 A;  1W1T A;  1WAW A;  5HW6 A;  4QIB A;  1SR0 A;  5GQB A;  4KR0 B;  1W1Y A;  2ZR5 A;  2FDM A;  4ODR A;  4IT4 A;  4DZ3 A;  4TW6 A;  3ARO A;  3NRK A;  4ZPT R;  2ZQT A;  3PA7 A;  1K9T A;  3ARY A;  4N19 A;  4DRQ A;  1FFR A;  2YBU A;  3UI5 A;  2A3C A;  3WH0 A;  1LG2 A;  4DWS C;  1A7X A;  4ITZ A;  1HXV A;  2K8I A;  3B9E A;  4NSB A;  5GPG A;  3PRD A;  3TCZ A;  3RFW A;  4MTV A;  3AS1 A;  1M5Y A;  1OGB A;  2KFW A;  3O5J A;  4PTM A;  1FKB A;  1NMW A;  1FKG A;  5BXJ A;  4TW7 A;  1PBK A;  2A3E A;  2Y78 A;  2FAP A;  3RGC A;  1R9H A;  4NZC A;  2F21 A;  2KR7 A;  3ALG A;  4G2P A;  4ODO A;  3FAP A;  4WKF A;  4LAW A;  1E15 A;  3ARX A;  2PBC A;  4DRP A;  2A3B A;  2O92 A;  1ZBC A;  3O5L A;  2ZR6 A;  1E9L A;  4MNK A;  1EHN A;  3B7X A;  2AWG A;  1OGG A;  1LQ0 A;  3O5R A;  3LUO A;  1FKJ A;  2DT0 A;  2DT3 A;  2DSU A;  4DT4 A;  3AS2 A;  2A3A A;  1U79 A;  1ITX A;  3UI6 A;  2DT1 A;  3UI4 A;  1Q1C A;  3RM8 A;  1UR9 A;  1FKL A;  2UZ5 A;  2WLZ A;  4S3J A;  2FKE A;  4P8V A;  4QT2 A;  3O5O A;  1NMV A;  1NWR A;  4JFK A;  1WB0 A;  1TCO C;  4DWS B;  4ZPW R;  3RM4 A;  2RUC A;  1H0I A;  4Z2J A;  4P8W A;  3UQB A;  4P8X A;  3G6M A;  3WD3 A;  1BL4 A;  2WM0 A;  4DRJ A;  4MSP A;  4Z2G A;  3CHE A;  1C9H A;  4ODP A;  2XP7 A;  3PRA A;  4DZ2 A;  4ODL A;  2LGO A;  4C02 B;  1E6Z A;  3CHF A;  2G41 A;  3O5Q A;  4WK9 A;  4JFI A;  1QPF A;  4GGQ A;  1TFV A;  3ARS A;  3KZ7 A;  2VCD A;  3WL1 A;  1FKK A;  5DIT A;  1W26 A;  4IPX A;  5HW7 A;  1D7I A;  1FAP A;  3QOK A;  3B9A A;  1J4R A;  4Z2K A;  3PR9 A;  5J6E A;  5HUA A;  3WQW A;  4WKH A;  1X6N A;  1Q6H A;  4Q22 A;  1ZBK A;  2KGJ A;  1ZK6 A;  3WL0 A;  1D7H A;  2KI3 A;  1WNO A;  2DG9 A;  3KCE A;  3FXY A;  1KT0 A;  3JYM A;  1L1P A;  4HBE A;  3AS3 A;  3CGN A;  1NH6 A;  1W1V A;  4HBO A;  3WIJ A;  3O5K A;  2O9O A;  2IF4 A;  3BXW A;  4J4O A;  4W5U A;  2F2D A;  2KO7 A;  2OLH A;  3WD0 A;  3FY1 A;  1JVW A;  2Q5A A;  1Q6U A;  4WJX A;  1W9P A;  1ZBW A;  3O5G A;  1FD9 A;  1ROT A;  4TYO A;  4W9O A;  2LKN A;  3KAG A;  4DRM A;  3KAB A;  2XP3 A;  2XPA A;  4AY1 A;  4TNS A;  4Z2L A;  3ODK A;  3OA5 A;  2AOS A;  1ZCN A;  1E6N A;  2RUR A;  1LL6 A;  1LG1 A;  1W9U A;  3O5I A;  4JFJ A;  1X6L A;  2G8Z A;  3OOB A;  2PPP A;  5DIU A;  3ARV A;  4P8U A;  3UQI A;  1HKJ A;  3RME A;  4J4N A;  1JNE A;  2XP4 A;  1NWS A;  2ESC A;  4HAR A;  4ZS6 A;  4QT3 A;  4URI A;  2D9F A;  1F8A B;  3ARQ A;  3UF8 A;  2LPV A;  1OWQ A;  1F40 A;  1YAT A;  2LJ4 A;  1FJD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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