2FGHA

Atp bound gelsolin
Total Genus 210
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
210
sequence length
729
structure length
721
Chain Sequence
VEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGILQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLLQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIYQWCGSKSNRFERLKATQVSKGIRDNERSGRAQVSVFEEGAEPEAMLQVLGPKPTLPEATENRKLAKLYKVSNGAGPMVVSLVADENPFAQGALRSEDCFILDHGKDGKIFVWKGKQANMEERKAALKTASDFISKMDYPKQTQVSVLPEGGETPLFRQFFKNWRDPDQTEGLGLAYLSSHIAHVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRVEGSNKVPVDPATYGQFYGGDSYIILYNYRHGSRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIVYKGGTSREGGQTAPASTRLFQVRASSSGATRAVEIIPKAGALNSNDAFVLKTPSAAYLWVGAGASEAEKTGAQELLRVLRAQPVQVAEGSEPDSFWEALGGKATYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGEFMQEDLATDDVMLLDTWDQVFVWVGKDSQDEEKTEALTSAKRYIDTDPAHRDRRTPITVVKQGFEPPSFVGWFLGWDDSYWSVDPLDRALAELAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structure of gelsolin bound to ATP
pubmed doi rcsb
molecule tags Contractile protein, structural protein
molecule keywords gelsolin
total genus 210
structure length 721
sequence length 729
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA02
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA01
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA04
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA06
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA05
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA03
5KYUB 1V6FA 3EH2A 2FH2A 2NUPA 3DAWB 1D4XG 2I2QA 2MV2A 3CIPG 3EH1A 1YVNG 1J72A 1NM1G 1SVQA 3EGXA 5IVUA 2NUTB 1DEJS 3EG9A 3EFOB 1CNUA 3A5LS 1QPVA 5KYWA 5KYYB 1VFQA 2VILA 3CI5G 1C0GS 1EQYS 1NMDG 2XFAA 3FFKA 1KCQA 1M2VB 2HD7A 2LJ8A 4Z94G 1ESVS 5KYUA 1SVRA 5HVKB 1RGIG 1PD0A 5FAFA 1HQZ1 1P8XA 1Q8GA 3EFOA 2FGHA 4S10C 2KVKA 4CBWG 1NLVG 2FH3A 4KEFA 4CBXG 5KYWB 3A5NS 4BEX1 3FG6A 4PKGG 5KYNA 1AK6A 3FFNA 1AHQA 1TMWA 2FH4A 3EGXB 1YAGG 1JHWA 2D8BA 1D0NA 2XF1A 1UDMA 1T44G 4KEEA 5KYXA 2VACA 4PKIG 2QTVA 5KYYA 2LXXA 3A5MS 1Q8XA 1PD1A 2FF6G 1M4JA 1MDUA 4JD2H 4LIZA 3TU5B 3CJCG 5A1MA 3Q2BA 1T2LA 4CBUG 3A5OS 2L72A 1WNJA 3L50A 1PCXA 2MOTA 2NUPB 1P8ZG 1M2OA 5L6WC 1H1VG 3EGDA 1NPHA 2MP4A 1COFA 1T3YA 4KEDA 5KYXB 1C0FS 4PKHB 1F7SA 1VKKA 2NUTA 5DD2A 1X67A 5HVKD 2VIKA 2LLFA 1TVJA 1WFSA 2FH1A 3FG7A 1T3XA 1CFYA 3CJBG 1SVYA 2W0IA 1WM4A 1M2VA 3EG9B 5FAEA 1AK7A 3EGDB 2FF3A
chains in the Genus database with same CATH superfamily
5KYUB 1V6FA 3EH2A 2FH2A 2NUPA 3DAWB 1D4XG 2I2QA 2MV2A 3CIPG 3EH1A 1YVNG 1J72A 1NM1G 1SVQA 3EGXA 5IVUA 2NUTB 1DEJS 3EG9A 3EFOB 1CNUA 3A5LS 1QPVA 5KYWA 5KYYB 1VFQA 2VILA 3CI5G 1C0GS 1EQYS 1NMDG 2XFAA 3FFKA 1KCQA 1M2VB 2HD7A 2LJ8A 4Z94G 1ESVS 5KYUA 1SVRA 5HVKB 1RGIG 1PD0A 5FAFA 1HQZ1 1P8XA 1Q8GA 3EFOA 2FGHA 4S10C 2KVKA 4CBWG 1NLVG 2FH3A 4KEFA 4CBXG 5KYWB 3A5NS 4BEX1 3FG6A 4PKGG 5KYNA 1AK6A 3FFNA 1AHQA 1TMWA 2FH4A 3EGXB 1YAGG 1JHWA 2D8BA 1D0NA 2XF1A 1UDMA 1T44G 4KEEA 5KYXA 2VACA 4PKIG 2QTVA 5KYYA 2LXXA 3A5MS 3DA7A 1Q8XA 1PD1A 2FF6G 1M4JA 1MDUA 4JD2H 4LIZA 3TU5B 3CJCG 5A1MA 3Q2BA 1T2LA 4CBUG 3A5OS 2L72A 1WNJA 3L50A 1PCXA 2MOTA 2NUPB 1P8ZG 1M2OA 5L6WC 1H1VG 3EGDA 1NPHA 2MP4A 1COFA 1T3YA 4KEDA 5KYXB 1C0FS 4PKHB 1F7SA 1VKKA 2NUTA 5DD2A 1X67A 5HVKD 2VIKA 2LLFA 1TVJA 1WFSA 2FH1A 3FG7A 1T3XA 1CFYA 3CJBG 1SVYA 2W0IA 1WM4A 1M2VA 3EG9B 5FAEA 1AK7A 3EGDB 2FF3A
chains in the Genus database with same CATH topology
5KYUB 1V6FA 3EH2A 2FH2A 2NUPA 3DAWB 1D4XG 2I2QA 2MV2A 3CIPG 3EH1A 1YVNG 1J72A 1NM1G 1SVQA 3EGXA 5IVUA 2NUTB 1DEJS 3EG9A 3EFOB 1CNUA 3A5LS 1QPVA 5KYWA 5KYYB 1VFQA 2VILA 3CI5G 1C0GS 1EQYS 1NMDG 2XFAA 3FFKA 1KCQA 1M2VB 2HD7A 2LJ8A 4Z94G 1ESVS 5KYUA 1SVRA 5HVKB 1RGIG 1PD0A 5FAFA 1HQZ1 1P8XA 1Q8GA 3EFOA 2FGHA 4S10C 2KVKA 4CBWG 1NLVG 2FH3A 4KEFA 4CBXG 5KYWB 3A5NS 4BEX1 3FG6A 4PKGG 5KYNA 1AK6A 3FFNA 1AHQA 1TMWA 2FH4A 3EGXB 1YAGG 1JHWA 2D8BA 1D0NA 2XF1A 1UDMA 1T44G 4KEEA 5KYXA 2VACA 4PKIG 2QTVA 5KYYA 2LXXA 3A5MS 3DA7A 1Q8XA 1PD1A 2FF6G 1M4JA 1MDUA 4JD2H 4LIZA 3TU5B 3CJCG 5A1MA 3Q2BA 1T2LA 4CBUG 3A5OS 2L72A 1WNJA 3L50A 1PCXA 2MOTA 2NUPB 1P8ZG 1M2OA 5L6WC 1H1VG 3EGDA 1NPHA 2MP4A 1COFA 1T3YA 4KEDA 5KYXB 1C0FS 4PKHB 1F7SA 1VKKA 2NUTA 5DD2A 1X67A 5HVKD 2VIKA 2LLFA 1TVJA 1WFSA 2FH1A 3FG7A 1T3XA 1CFYA 3CJBG 1SVYA 2W0IA 1WM4A 1M2VA 3EG9B 5FAEA 1AK7A 3EGDB 2FF3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5KYU B;  1V6F A;  3EH2 A;  2FH2 A;  2NUP A;  3DAW B;  1D4X G;  2I2Q A;  2MV2 A;  3CIP G;  3EH1 A;  1YVN G;  1J72 A;  1NM1 G;  1SVQ A;  3EGX A;  5IVU A;  2NUT B;  1DEJ S;  3EG9 A;  3EFO B;  1CNU A;  3A5L S;  1QPV A;  5KYW A;  5KYY B;  1VFQ A;  2VIL A;  3CI5 G;  1C0G S;  1EQY S;  1NMD G;  2XFA A;  3FFK A;  1KCQ A;  1M2V B;  2HD7 A;  2LJ8 A;  4Z94 G;  1ESV S;  5KYU A;  1SVR A;  5HVK B;  1RGI G;  1PD0 A;  5FAF A;  1HQZ 1;  1P8X A;  1Q8G A;  3EFO A;  2FGH A;  4S10 C;  2KVK A;  4CBW G;  1NLV G;  2FH3 A;  4KEF A;  4CBX G;  5KYW B;  3A5N S;  4BEX 1;  3FG6 A;  4PKG G;  5KYN A;  1AK6 A;  3FFN A;  1AHQ A;  1TMW A;  2FH4 A;  3EGX B;  1YAG G;  1JHW A;  2D8B A;  1D0N A;  2XF1 A;  1UDM A;  1T44 G;  4KEE A;  5KYX A;  2VAC A;  4PKI G;  2QTV A;  5KYY A;  2LXX A;  3A5M S;  1Q8X A;  1PD1 A;  2FF6 G;  1M4J A;  1MDU A;  4JD2 H;  4LIZ A;  3TU5 B;  3CJC G;  5A1M A;  3Q2B A;  1T2L A;  4CBU G;  3A5O S;  2L72 A;  1WNJ A;  3L50 A;  1PCX A;  2MOT A;  2NUP B;  1P8Z G;  1M2O A;  5L6W C;  1H1V G;  3EGD A;  1NPH A;  2MP4 A;  1COF A;  1T3Y A;  4KED A;  5KYX B;  1C0F S;  4PKH B;  1F7S A;  1VKK A;  2NUT A;  5DD2 A;  1X67 A;  5HVK D;  2VIK A;  2LLF A;  1TVJ A;  1WFS A;  2FH1 A;  3FG7 A;  1T3X A;  1CFY A;  3CJB G;  1SVY A;  2W0I A;  1WM4 A;  1M2V A;  3EG9 B;  5FAE A;  1AK7 A;  3EGD B;  2FF3 A; 
#chains in the Genus database with same CATH topology
 5KYU B;  1V6F A;  3EH2 A;  2FH2 A;  2NUP A;  3DAW B;  1D4X G;  2I2Q A;  2MV2 A;  3CIP G;  3EH1 A;  1YVN G;  1J72 A;  1NM1 G;  1SVQ A;  3EGX A;  5IVU A;  2NUT B;  1DEJ S;  3EG9 A;  3EFO B;  1CNU A;  3A5L S;  1QPV A;  5KYW A;  5KYY B;  1VFQ A;  2VIL A;  3CI5 G;  1C0G S;  1EQY S;  1NMD G;  2XFA A;  3FFK A;  1KCQ A;  1M2V B;  2HD7 A;  2LJ8 A;  4Z94 G;  1ESV S;  5KYU A;  1SVR A;  5HVK B;  1RGI G;  1PD0 A;  5FAF A;  1HQZ 1;  1P8X A;  1Q8G A;  3EFO A;  2FGH A;  4S10 C;  2KVK A;  4CBW G;  1NLV G;  2FH3 A;  4KEF A;  4CBX G;  5KYW B;  3A5N S;  4BEX 1;  3FG6 A;  4PKG G;  5KYN A;  1AK6 A;  3FFN A;  1AHQ A;  1TMW A;  2FH4 A;  3EGX B;  1YAG G;  1JHW A;  2D8B A;  1D0N A;  2XF1 A;  1UDM A;  1T44 G;  4KEE A;  5KYX A;  2VAC A;  4PKI G;  2QTV A;  5KYY A;  2LXX A;  3A5M S;  3DA7 A;  1Q8X A;  1PD1 A;  2FF6 G;  1M4J A;  1MDU A;  4JD2 H;  4LIZ A;  3TU5 B;  3CJC G;  5A1M A;  3Q2B A;  1T2L A;  4CBU G;  3A5O S;  2L72 A;  1WNJ A;  3L50 A;  1PCX A;  2MOT A;  2NUP B;  1P8Z G;  1M2O A;  5L6W C;  1H1V G;  3EGD A;  1NPH A;  2MP4 A;  1COF A;  1T3Y A;  4KED A;  5KYX B;  1C0F S;  4PKH B;  1F7S A;  1VKK A;  2NUT A;  5DD2 A;  1X67 A;  5HVK D;  2VIK A;  2LLF A;  1TVJ A;  1WFS A;  2FH1 A;  3FG7 A;  1T3X A;  1CFY A;  3CJB G;  1SVY A;  2W0I A;  1WM4 A;  1M2V A;  3EG9 B;  5FAE A;  1AK7 A;  3EGD B;  2FF3 A; 
#chains in the Genus database with same CATH homology
 5KYU B;  1V6F A;  3EH2 A;  2FH2 A;  2NUP A;  3DAW B;  1D4X G;  2I2Q A;  2MV2 A;  3CIP G;  3EH1 A;  1YVN G;  1J72 A;  1NM1 G;  1SVQ A;  3EGX A;  5IVU A;  2NUT B;  1DEJ S;  3EG9 A;  3EFO B;  1CNU A;  3A5L S;  1QPV A;  5KYW A;  5KYY B;  1VFQ A;  2VIL A;  3CI5 G;  1C0G S;  1EQY S;  1NMD G;  2XFA A;  3FFK A;  1KCQ A;  1M2V B;  2HD7 A;  2LJ8 A;  4Z94 G;  1ESV S;  5KYU A;  1SVR A;  5HVK B;  1RGI G;  1PD0 A;  5FAF A;  1HQZ 1;  1P8X A;  1Q8G A;  3EFO A;  2FGH A;  4S10 C;  2KVK A;  4CBW G;  1NLV G;  2FH3 A;  4KEF A;  4CBX G;  5KYW B;  3A5N S;  4BEX 1;  3FG6 A;  4PKG G;  5KYN A;  1AK6 A;  3FFN A;  1AHQ A;  1TMW A;  2FH4 A;  3EGX B;  1YAG G;  1JHW A;  2D8B A;  1D0N A;  2XF1 A;  1UDM A;  1T44 G;  4KEE A;  5KYX A;  2VAC A;  4PKI G;  2QTV A;  5KYY A;  2LXX A;  3A5M S;  3DA7 A;  1Q8X A;  1PD1 A;  2FF6 G;  1M4J A;  1MDU A;  4JD2 H;  4LIZ A;  3TU5 B;  3CJC G;  5A1M A;  3Q2B A;  1T2L A;  4CBU G;  3A5O S;  2L72 A;  1WNJ A;  3L50 A;  1PCX A;  2MOT A;  2NUP B;  1P8Z G;  1M2O A;  5L6W C;  1H1V G;  3EGD A;  1NPH A;  2MP4 A;  1COF A;  1T3Y A;  4KED A;  5KYX B;  1C0F S;  4PKH B;  1F7S A;  1VKK A;  2NUT A;  5DD2 A;  1X67 A;  5HVK D;  2VIK A;  2LLF A;  1TVJ A;  1WFS A;  2FH1 A;  3FG7 A;  1T3X A;  1CFY A;  3CJB G;  1SVY A;  2W0I A;  1WM4 A;  1M2V A;  3EG9 B;  5FAE A;  1AK7 A;  3EGD B;  2FF3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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