2FGHA

Atp bound gelsolin
Total Genus 210
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
210
sequence length
729
structure length
721
Chain Sequence
VEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGILQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLLQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIYQWCGSKSNRFERLKATQVSKGIRDNERSGRAQVSVFEEGAEPEAMLQVLGPKPTLPEATENRKLAKLYKVSNGAGPMVVSLVADENPFAQGALRSEDCFILDHGKDGKIFVWKGKQANMEERKAALKTASDFISKMDYPKQTQVSVLPEGGETPLFRQFFKNWRDPDQTEGLGLAYLSSHIAHVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRVEGSNKVPVDPATYGQFYGGDSYIILYNYRHGSRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIVYKGGTSREGGQTAPASTRLFQVRASSSGATRAVEIIPKAGALNSNDAFVLKTPSAAYLWVGAGASEAEKTGAQELLRVLRAQPVQVAEGSEPDSFWEALGGKATYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGEFMQEDLATDDVMLLDTWDQVFVWVGKDSQDEEKTEALTSAKRYIDTDPAHRDRRTPITVVKQGFEPPSFVGWFLGWDDSYWSVDPLDRALAELAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structure of gelsolin bound to ATP
pubmed doi rcsb
molecule tags Contractile protein, structural protein
molecule keywords gelsolin
total genus 210
structure length 721
sequence length 729
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA02
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA01
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA04
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA06
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA05
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA03
4S10C 3EG9A 1Q8GA 4JD2H 1VFQA 4CBUG 1WM4A 3EH2A 2W0IA 5DD2A 1NM1G 3Q2BA 5L6WC 1Q8XA 3CJCG 2FGHA 1AHQA 2FF6G 1M2VB 3FFNA 1T44G 2MV2A 5KYXA 1T3YA 4BEX1 1X67A 3CJBG 1TVJA 2FH3A 5FAFA 3FG7A 5HVKB 1PD0A 3EGXB 5KYYB 1P8XA 5A1MA 1PD1A 1YAGG 4Z94G 4CBXG 1M4JA 3CIPG 4PKHB 2VIKA 5KYYA 2FH4A 1T3XA 5KYWA 1NPHA 3CI5G 1C0FS 1EQYS 3A5MS 5IVUA 1UDMA 3FG6A 2FH2A 3FFKA 1RGIG 2D8BA 1D4XG 2FH1A 1KCQA 2VILA 1QPVA 3EGDB 5KYXB 1SVRA 5FAEA 2NUPB 2NUTA 3A5LS 2FF3A 4KEFA 3EH1A 2NUPA 1M2OA 1CFYA 3L50A 1T2LA 1NLVG 3A5OS 1JHWA 1NMDG 2MP4A 1J72A 2QTVA 2HD7A 4KEDA 1TMWA 2KVKA 2I2QA 1H1VG 3DAWB 3EG9B 1PCXA 4PKIG 5KYUA 4KEEA 1SVYA 4LIZA 1CNUA 1SVQA 3EGXA 1D0NA 4PKGG 3TU5B 1YVNG 1F7SA 5KYUB 1WFSA 1C0GS 2NUTB 2VACA 5KYNA 1DEJS 2L72A 1HQZ1 2LJ8A 2XFAA 3A5NS 4CBWG 1P8ZG 5KYWB 1V6FA 3EFOB 1ESVS 1M2VA 1VKKA 2LXXA 2XF1A 1WNJA 2MOTA 1COFA 1AK6A 5HVKD 1MDUA 3EFOA 2LLFA 1AK7A 3EGDA
chains in the Genus database with same CATH superfamily
4S10C 3EG9A 1Q8GA 4JD2H 1VFQA 4CBUG 1WM4A 3EH2A 2W0IA 5DD2A 1NM1G 3Q2BA 5L6WC 1Q8XA 3CJCG 2FGHA 1AHQA 2FF6G 1M2VB 3FFNA 1T44G 2MV2A 5KYXA 1T3YA 4BEX1 1X67A 3CJBG 1TVJA 2FH3A 5FAFA 3FG7A 5HVKB 1PD0A 3EGXB 5KYYB 1P8XA 5A1MA 1PD1A 1YAGG 4Z94G 4CBXG 1M4JA 3CIPG 4PKHB 2VIKA 5KYYA 2FH4A 1T3XA 5KYWA 1NPHA 3CI5G 3DA7A 1C0FS 1EQYS 3A5MS 5IVUA 1UDMA 3FG6A 2FH2A 3FFKA 1RGIG 2D8BA 1D4XG 2FH1A 1KCQA 2VILA 1QPVA 3EGDB 5KYXB 1SVRA 5FAEA 2NUPB 2NUTA 3A5LS 2FF3A 4KEFA 3EH1A 2NUPA 1M2OA 1CFYA 3L50A 1T2LA 1NLVG 3A5OS 1JHWA 1NMDG 2MP4A 1J72A 2QTVA 2HD7A 4KEDA 1TMWA 2KVKA 2I2QA 1H1VG 3DAWB 3EG9B 1PCXA 4PKIG 5KYUA 4KEEA 1SVYA 4LIZA 1CNUA 1SVQA 3EGXA 1D0NA 4PKGG 3TU5B 1YVNG 1F7SA 5KYUB 1WFSA 1C0GS 2NUTB 2VACA 5KYNA 1DEJS 2L72A 1HQZ1 2LJ8A 2XFAA 3A5NS 4CBWG 1P8ZG 5KYWB 1V6FA 3EFOB 1ESVS 1M2VA 1VKKA 2LXXA 2XF1A 1WNJA 2MOTA 1COFA 1AK6A 5HVKD 1MDUA 3EFOA 2LLFA 1AK7A 3EGDA
chains in the Genus database with same CATH topology
4S10C 3EG9A 1Q8GA 4JD2H 1VFQA 4CBUG 1WM4A 3EH2A 2W0IA 5DD2A 1NM1G 3Q2BA 5L6WC 1Q8XA 3CJCG 2FGHA 1AHQA 2FF6G 1M2VB 3FFNA 1T44G 2MV2A 5KYXA 1T3YA 4BEX1 1X67A 3CJBG 1TVJA 2FH3A 5FAFA 3FG7A 5HVKB 1PD0A 3EGXB 5KYYB 1P8XA 5A1MA 1PD1A 1YAGG 4Z94G 4CBXG 1M4JA 3CIPG 4PKHB 2VIKA 5KYYA 2FH4A 1T3XA 5KYWA 1NPHA 3CI5G 3DA7A 1C0FS 1EQYS 3A5MS 5IVUA 1UDMA 3FG6A 2FH2A 3FFKA 1RGIG 2D8BA 1D4XG 2FH1A 1KCQA 2VILA 1QPVA 3EGDB 5KYXB 1SVRA 5FAEA 2NUPB 2NUTA 3A5LS 2FF3A 4KEFA 3EH1A 2NUPA 1M2OA 1CFYA 3L50A 1T2LA 1NLVG 3A5OS 1JHWA 1NMDG 2MP4A 1J72A 2QTVA 2HD7A 4KEDA 1TMWA 2KVKA 2I2QA 1H1VG 3DAWB 3EG9B 1PCXA 4PKIG 5KYUA 4KEEA 1SVYA 4LIZA 1CNUA 1SVQA 3EGXA 1D0NA 4PKGG 3TU5B 1YVNG 1F7SA 5KYUB 1WFSA 1C0GS 2NUTB 2VACA 5KYNA 1DEJS 2L72A 1HQZ1 2LJ8A 2XFAA 3A5NS 4CBWG 1P8ZG 5KYWB 1V6FA 3EFOB 1ESVS 1M2VA 1VKKA 2LXXA 2XF1A 1WNJA 2MOTA 1COFA 1AK6A 5HVKD 1MDUA 3EFOA 2LLFA 1AK7A 3EGDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4S10 C;  3EG9 A;  1Q8G A;  4JD2 H;  1VFQ A;  4CBU G;  1WM4 A;  3EH2 A;  2W0I A;  5DD2 A;  1NM1 G;  3Q2B A;  5L6W C;  1Q8X A;  3CJC G;  2FGH A;  1AHQ A;  2FF6 G;  1M2V B;  3FFN A;  1T44 G;  2MV2 A;  5KYX A;  1T3Y A;  4BEX 1;  1X67 A;  3CJB G;  1TVJ A;  2FH3 A;  5FAF A;  3FG7 A;  5HVK B;  1PD0 A;  3EGX B;  5KYY B;  1P8X A;  5A1M A;  1PD1 A;  1YAG G;  4Z94 G;  4CBX G;  1M4J A;  3CIP G;  4PKH B;  2VIK A;  5KYY A;  2FH4 A;  1T3X A;  5KYW A;  1NPH A;  3CI5 G;  1C0F S;  1EQY S;  3A5M S;  5IVU A;  1UDM A;  3FG6 A;  2FH2 A;  3FFK A;  1RGI G;  2D8B A;  1D4X G;  2FH1 A;  1KCQ A;  2VIL A;  1QPV A;  3EGD B;  5KYX B;  1SVR A;  5FAE A;  2NUP B;  2NUT A;  3A5L S;  2FF3 A;  4KEF A;  3EH1 A;  2NUP A;  1M2O A;  1CFY A;  3L50 A;  1T2L A;  1NLV G;  3A5O S;  1JHW A;  1NMD G;  2MP4 A;  1J72 A;  2QTV A;  2HD7 A;  4KED A;  1TMW A;  2KVK A;  2I2Q A;  1H1V G;  3DAW B;  3EG9 B;  1PCX A;  4PKI G;  5KYU A;  4KEE A;  1SVY A;  4LIZ A;  1CNU A;  1SVQ A;  3EGX A;  1D0N A;  4PKG G;  3TU5 B;  1YVN G;  1F7S A;  5KYU B;  1WFS A;  1C0G S;  2NUT B;  2VAC A;  5KYN A;  1DEJ S;  2L72 A;  1HQZ 1;  2LJ8 A;  2XFA A;  3A5N S;  4CBW G;  1P8Z G;  5KYW B;  1V6F A;  3EFO B;  1ESV S;  1M2V A;  1VKK A;  2LXX A;  2XF1 A;  1WNJ A;  2MOT A;  1COF A;  1AK6 A;  5HVK D;  1MDU A;  3EFO A;  2LLF A;  1AK7 A;  3EGD A; 
#chains in the Genus database with same CATH topology
 4S10 C;  3EG9 A;  1Q8G A;  4JD2 H;  1VFQ A;  4CBU G;  1WM4 A;  3EH2 A;  2W0I A;  5DD2 A;  1NM1 G;  3Q2B A;  5L6W C;  1Q8X A;  3CJC G;  2FGH A;  1AHQ A;  2FF6 G;  1M2V B;  3FFN A;  1T44 G;  2MV2 A;  5KYX A;  1T3Y A;  4BEX 1;  1X67 A;  3CJB G;  1TVJ A;  2FH3 A;  5FAF A;  3FG7 A;  5HVK B;  1PD0 A;  3EGX B;  5KYY B;  1P8X A;  5A1M A;  1PD1 A;  1YAG G;  4Z94 G;  4CBX G;  1M4J A;  3CIP G;  4PKH B;  2VIK A;  5KYY A;  2FH4 A;  1T3X A;  5KYW A;  1NPH A;  3CI5 G;  3DA7 A;  1C0F S;  1EQY S;  3A5M S;  5IVU A;  1UDM A;  3FG6 A;  2FH2 A;  3FFK A;  1RGI G;  2D8B A;  1D4X G;  2FH1 A;  1KCQ A;  2VIL A;  1QPV A;  3EGD B;  5KYX B;  1SVR A;  5FAE A;  2NUP B;  2NUT A;  3A5L S;  2FF3 A;  4KEF A;  3EH1 A;  2NUP A;  1M2O A;  1CFY A;  3L50 A;  1T2L A;  1NLV G;  3A5O S;  1JHW A;  1NMD G;  2MP4 A;  1J72 A;  2QTV A;  2HD7 A;  4KED A;  1TMW A;  2KVK A;  2I2Q A;  1H1V G;  3DAW B;  3EG9 B;  1PCX A;  4PKI G;  5KYU A;  4KEE A;  1SVY A;  4LIZ A;  1CNU A;  1SVQ A;  3EGX A;  1D0N A;  4PKG G;  3TU5 B;  1YVN G;  1F7S A;  5KYU B;  1WFS A;  1C0G S;  2NUT B;  2VAC A;  5KYN A;  1DEJ S;  2L72 A;  1HQZ 1;  2LJ8 A;  2XFA A;  3A5N S;  4CBW G;  1P8Z G;  5KYW B;  1V6F A;  3EFO B;  1ESV S;  1M2V A;  1VKK A;  2LXX A;  2XF1 A;  1WNJ A;  2MOT A;  1COF A;  1AK6 A;  5HVK D;  1MDU A;  3EFO A;  2LLF A;  1AK7 A;  3EGD A; 
#chains in the Genus database with same CATH homology
 4S10 C;  3EG9 A;  1Q8G A;  4JD2 H;  1VFQ A;  4CBU G;  1WM4 A;  3EH2 A;  2W0I A;  5DD2 A;  1NM1 G;  3Q2B A;  5L6W C;  1Q8X A;  3CJC G;  2FGH A;  1AHQ A;  2FF6 G;  1M2V B;  3FFN A;  1T44 G;  2MV2 A;  5KYX A;  1T3Y A;  4BEX 1;  1X67 A;  3CJB G;  1TVJ A;  2FH3 A;  5FAF A;  3FG7 A;  5HVK B;  1PD0 A;  3EGX B;  5KYY B;  1P8X A;  5A1M A;  1PD1 A;  1YAG G;  4Z94 G;  4CBX G;  1M4J A;  3CIP G;  4PKH B;  2VIK A;  5KYY A;  2FH4 A;  1T3X A;  5KYW A;  1NPH A;  3CI5 G;  3DA7 A;  1C0F S;  1EQY S;  3A5M S;  5IVU A;  1UDM A;  3FG6 A;  2FH2 A;  3FFK A;  1RGI G;  2D8B A;  1D4X G;  2FH1 A;  1KCQ A;  2VIL A;  1QPV A;  3EGD B;  5KYX B;  1SVR A;  5FAE A;  2NUP B;  2NUT A;  3A5L S;  2FF3 A;  4KEF A;  3EH1 A;  2NUP A;  1M2O A;  1CFY A;  3L50 A;  1T2L A;  1NLV G;  3A5O S;  1JHW A;  1NMD G;  2MP4 A;  1J72 A;  2QTV A;  2HD7 A;  4KED A;  1TMW A;  2KVK A;  2I2Q A;  1H1V G;  3DAW B;  3EG9 B;  1PCX A;  4PKI G;  5KYU A;  4KEE A;  1SVY A;  4LIZ A;  1CNU A;  1SVQ A;  3EGX A;  1D0N A;  4PKG G;  3TU5 B;  1YVN G;  1F7S A;  5KYU B;  1WFS A;  1C0G S;  2NUT B;  2VAC A;  5KYN A;  1DEJ S;  2L72 A;  1HQZ 1;  2LJ8 A;  2XFA A;  3A5N S;  4CBW G;  1P8Z G;  5KYW B;  1V6F A;  3EFO B;  1ESV S;  1M2V A;  1VKK A;  2LXX A;  2XF1 A;  1WNJ A;  2MOT A;  1COF A;  1AK6 A;  5HVK D;  1MDU A;  3EFO A;  2LLF A;  1AK7 A;  3EGD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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