2FGHA

Atp bound gelsolin
Total Genus 210
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
210
sequence length
729
structure length
721
Chain Sequence
VEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGILQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLLQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIYQWCGSKSNRFERLKATQVSKGIRDNERSGRAQVSVFEEGAEPEAMLQVLGPKPTLPEATENRKLAKLYKVSNGAGPMVVSLVADENPFAQGALRSEDCFILDHGKDGKIFVWKGKQANMEERKAALKTASDFISKMDYPKQTQVSVLPEGGETPLFRQFFKNWRDPDQTEGLGLAYLSSHIAHVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRVEGSNKVPVDPATYGQFYGGDSYIILYNYRHGSRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIVYKGGTSREGGQTAPASTRLFQVRASSSGATRAVEIIPKAGALNSNDAFVLKTPSAAYLWVGAGASEAEKTGAQELLRVLRAQPVQVAEGSEPDSFWEALGGKATYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGEFMQEDLATDDVMLLDTWDQVFVWVGKDSQDEEKTEALTSAKRYIDTDPAHRDRRTPITVVKQGFEPPSFVGWFLGWDDSYWSVDPLDRALAELAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structure of gelsolin bound to ATP
pubmed doi rcsb
molecule tags Contractile protein, structural protein
molecule keywords gelsolin
total genus 210
structure length 721
sequence length 729
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA02
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA01
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA04
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA06
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA05
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fghA03
1YVNG 3CJBG 3L50A 5DD2A 4Z94G 1NMDG 2NUTA 1SVYA 1T3XA 1YAGG 1CFYA 2W0IA 1UDMA 2LLFA 5FAEA 5HVKB 1AK6A 3EH1A 1Q8XA 2KVKA 1WM4A 2I2QA 1RGIG 2HD7A 2FH2A 5KYWB 3A5NS 5IVUA 3TU5B 5KYNA 1VFQA 2FH4A 1TMWA 2VILA 1NLVG 5KYXB 2FH3A 3FFKA 1PD1A 1VKKA 1JHWA 1QPVA 4KEDA 3EGXA 1NPHA 1DEJS 1SVRA 5KYYB 3EH2A 2FGHA 1Q8GA 3EG9B 1ESVS 1SVQA 1T2LA 3EFOB 1M2OA 2NUPB 1T3YA 1M2VA 3CJCG 1F7SA 1C0GS 1C0FS 4CBXG 2XF1A 1TVJA 1WNJA 5KYUB 3CI5G 1AK7A 4S10C 4KEFA 2FF3A 2MV2A 1COFA 1D4XG 3DAWB 2D8BA 5KYYA 1X67A 3EGDB 2L72A 4PKHB 1PCXA 2VACA 2VIKA 2FF6G 2XFAA 3FG6A 3A5LS 3FG7A 4PKGG 3Q2BA 3A5MS 5A1MA 2LJ8A 5HVKD 1MDUA 4KEEA 5KYWA 1AHQA 1PD0A 5FAFA 1D0NA 1P8XA 1NM1G 1V6FA 4CBUG 2QTVA 5KYUA 3A5OS 4PKIG 4LIZA 1KCQA 1HQZ1 2FH1A 1EQYS 5KYXA 1M4JA 2LXXA 2NUTB 4BEX1 3FFNA 3EGXB 1WFSA 2MP4A 1H1VG 3CIPG 3EGDA 4JD2H 4CBWG 3EG9A 1P8ZG 2MOTA 3EFOA 1T44G 1CNUA 2NUPA 1J72A 5L6WC 1M2VB
chains in the Genus database with same CATH superfamily
1YVNG 3CJBG 3L50A 5DD2A 4Z94G 1NMDG 2NUTA 1SVYA 1T3XA 1YAGG 1CFYA 2W0IA 1UDMA 2LLFA 5FAEA 5HVKB 1AK6A 3EH1A 1Q8XA 2KVKA 1WM4A 2I2QA 1RGIG 2HD7A 2FH2A 5KYWB 3A5NS 5IVUA 3TU5B 5KYNA 1VFQA 2FH4A 1TMWA 2VILA 1NLVG 5KYXB 2FH3A 3FFKA 1PD1A 1VKKA 1JHWA 1QPVA 4KEDA 3EGXA 1NPHA 1DEJS 1SVRA 5KYYB 3EH2A 2FGHA 1Q8GA 3EG9B 1ESVS 1SVQA 1T2LA 3EFOB 1M2OA 2NUPB 1T3YA 1M2VA 3CJCG 1F7SA 1C0GS 1C0FS 4CBXG 2XF1A 1TVJA 1WNJA 5KYUB 3CI5G 1AK7A 4S10C 4KEFA 2FF3A 2MV2A 1COFA 1D4XG 3DAWB 2D8BA 5KYYA 1X67A 3EGDB 2L72A 4PKHB 1PCXA 2VACA 2VIKA 2FF6G 2XFAA 3FG6A 3A5LS 3FG7A 4PKGG 3Q2BA 3A5MS 5A1MA 2LJ8A 5HVKD 1MDUA 4KEEA 5KYWA 1AHQA 1PD0A 5FAFA 1D0NA 1P8XA 1NM1G 1V6FA 4CBUG 2QTVA 5KYUA 3A5OS 4PKIG 4LIZA 1KCQA 1HQZ1 2FH1A 1EQYS 5KYXA 1M4JA 2LXXA 2NUTB 4BEX1 3FFNA 3EGXB 1WFSA 2MP4A 1H1VG 3CIPG 3EGDA 4JD2H 4CBWG 3EG9A 1P8ZG 2MOTA 3DA7A 3EFOA 1T44G 1CNUA 2NUPA 1J72A 5L6WC 1M2VB
chains in the Genus database with same CATH topology
1YVNG 3CJBG 3L50A 5DD2A 4Z94G 1NMDG 2NUTA 1SVYA 1T3XA 1YAGG 1CFYA 2W0IA 1UDMA 2LLFA 5FAEA 5HVKB 1AK6A 3EH1A 1Q8XA 2KVKA 1WM4A 2I2QA 1RGIG 2HD7A 2FH2A 5KYWB 3A5NS 5IVUA 3TU5B 5KYNA 1VFQA 2FH4A 1TMWA 2VILA 1NLVG 5KYXB 2FH3A 3FFKA 1PD1A 1VKKA 1JHWA 1QPVA 4KEDA 3EGXA 1NPHA 1DEJS 1SVRA 5KYYB 3EH2A 2FGHA 1Q8GA 3EG9B 1ESVS 1SVQA 1T2LA 3EFOB 1M2OA 2NUPB 1T3YA 1M2VA 3CJCG 1F7SA 1C0GS 1C0FS 4CBXG 2XF1A 1TVJA 1WNJA 5KYUB 3CI5G 1AK7A 4S10C 4KEFA 2FF3A 2MV2A 1COFA 1D4XG 3DAWB 2D8BA 5KYYA 1X67A 3EGDB 2L72A 4PKHB 1PCXA 2VACA 2VIKA 2FF6G 2XFAA 3FG6A 3A5LS 3FG7A 4PKGG 3Q2BA 3A5MS 5A1MA 2LJ8A 5HVKD 1MDUA 4KEEA 5KYWA 1AHQA 1PD0A 5FAFA 1D0NA 1P8XA 1NM1G 1V6FA 4CBUG 2QTVA 5KYUA 3A5OS 4PKIG 4LIZA 1KCQA 1HQZ1 2FH1A 1EQYS 5KYXA 1M4JA 2LXXA 2NUTB 4BEX1 3FFNA 3EGXB 1WFSA 2MP4A 1H1VG 3CIPG 3EGDA 4JD2H 4CBWG 3EG9A 1P8ZG 2MOTA 3DA7A 3EFOA 1T44G 1CNUA 2NUPA 1J72A 5L6WC 1M2VB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YVN G;  3CJB G;  3L50 A;  5DD2 A;  4Z94 G;  1NMD G;  2NUT A;  1SVY A;  1T3X A;  1YAG G;  1CFY A;  2W0I A;  1UDM A;  2LLF A;  5FAE A;  5HVK B;  1AK6 A;  3EH1 A;  1Q8X A;  2KVK A;  1WM4 A;  2I2Q A;  1RGI G;  2HD7 A;  2FH2 A;  5KYW B;  3A5N S;  5IVU A;  3TU5 B;  5KYN A;  1VFQ A;  2FH4 A;  1TMW A;  2VIL A;  1NLV G;  5KYX B;  2FH3 A;  3FFK A;  1PD1 A;  1VKK A;  1JHW A;  1QPV A;  4KED A;  3EGX A;  1NPH A;  1DEJ S;  1SVR A;  5KYY B;  3EH2 A;  2FGH A;  1Q8G A;  3EG9 B;  1ESV S;  1SVQ A;  1T2L A;  3EFO B;  1M2O A;  2NUP B;  1T3Y A;  1M2V A;  3CJC G;  1F7S A;  1C0G S;  1C0F S;  4CBX G;  2XF1 A;  1TVJ A;  1WNJ A;  5KYU B;  3CI5 G;  1AK7 A;  4S10 C;  4KEF A;  2FF3 A;  2MV2 A;  1COF A;  1D4X G;  3DAW B;  2D8B A;  5KYY A;  1X67 A;  3EGD B;  2L72 A;  4PKH B;  1PCX A;  2VAC A;  2VIK A;  2FF6 G;  2XFA A;  3FG6 A;  3A5L S;  3FG7 A;  4PKG G;  3Q2B A;  3A5M S;  5A1M A;  2LJ8 A;  5HVK D;  1MDU A;  4KEE A;  5KYW A;  1AHQ A;  1PD0 A;  5FAF A;  1D0N A;  1P8X A;  1NM1 G;  1V6F A;  4CBU G;  2QTV A;  5KYU A;  3A5O S;  4PKI G;  4LIZ A;  1KCQ A;  1HQZ 1;  2FH1 A;  1EQY S;  5KYX A;  1M4J A;  2LXX A;  2NUT B;  4BEX 1;  3FFN A;  3EGX B;  1WFS A;  2MP4 A;  1H1V G;  3CIP G;  3EGD A;  4JD2 H;  4CBW G;  3EG9 A;  1P8Z G;  2MOT A;  3EFO A;  1T44 G;  1CNU A;  2NUP A;  1J72 A;  5L6W C;  1M2V B; 
#chains in the Genus database with same CATH topology
 1YVN G;  3CJB G;  3L50 A;  5DD2 A;  4Z94 G;  1NMD G;  2NUT A;  1SVY A;  1T3X A;  1YAG G;  1CFY A;  2W0I A;  1UDM A;  2LLF A;  5FAE A;  5HVK B;  1AK6 A;  3EH1 A;  1Q8X A;  2KVK A;  1WM4 A;  2I2Q A;  1RGI G;  2HD7 A;  2FH2 A;  5KYW B;  3A5N S;  5IVU A;  3TU5 B;  5KYN A;  1VFQ A;  2FH4 A;  1TMW A;  2VIL A;  1NLV G;  5KYX B;  2FH3 A;  3FFK A;  1PD1 A;  1VKK A;  1JHW A;  1QPV A;  4KED A;  3EGX A;  1NPH A;  1DEJ S;  1SVR A;  5KYY B;  3EH2 A;  2FGH A;  1Q8G A;  3EG9 B;  1ESV S;  1SVQ A;  1T2L A;  3EFO B;  1M2O A;  2NUP B;  1T3Y A;  1M2V A;  3CJC G;  1F7S A;  1C0G S;  1C0F S;  4CBX G;  2XF1 A;  1TVJ A;  1WNJ A;  5KYU B;  3CI5 G;  1AK7 A;  4S10 C;  4KEF A;  2FF3 A;  2MV2 A;  1COF A;  1D4X G;  3DAW B;  2D8B A;  5KYY A;  1X67 A;  3EGD B;  2L72 A;  4PKH B;  1PCX A;  2VAC A;  2VIK A;  2FF6 G;  2XFA A;  3FG6 A;  3A5L S;  3FG7 A;  4PKG G;  3Q2B A;  3A5M S;  5A1M A;  2LJ8 A;  5HVK D;  1MDU A;  4KEE A;  5KYW A;  1AHQ A;  1PD0 A;  5FAF A;  1D0N A;  1P8X A;  1NM1 G;  1V6F A;  4CBU G;  2QTV A;  5KYU A;  3A5O S;  4PKI G;  4LIZ A;  1KCQ A;  1HQZ 1;  2FH1 A;  1EQY S;  5KYX A;  1M4J A;  2LXX A;  2NUT B;  4BEX 1;  3FFN A;  3EGX B;  1WFS A;  2MP4 A;  1H1V G;  3CIP G;  3EGD A;  4JD2 H;  4CBW G;  3EG9 A;  1P8Z G;  2MOT A;  3DA7 A;  3EFO A;  1T44 G;  1CNU A;  2NUP A;  1J72 A;  5L6W C;  1M2V B; 
#chains in the Genus database with same CATH homology
 1YVN G;  3CJB G;  3L50 A;  5DD2 A;  4Z94 G;  1NMD G;  2NUT A;  1SVY A;  1T3X A;  1YAG G;  1CFY A;  2W0I A;  1UDM A;  2LLF A;  5FAE A;  5HVK B;  1AK6 A;  3EH1 A;  1Q8X A;  2KVK A;  1WM4 A;  2I2Q A;  1RGI G;  2HD7 A;  2FH2 A;  5KYW B;  3A5N S;  5IVU A;  3TU5 B;  5KYN A;  1VFQ A;  2FH4 A;  1TMW A;  2VIL A;  1NLV G;  5KYX B;  2FH3 A;  3FFK A;  1PD1 A;  1VKK A;  1JHW A;  1QPV A;  4KED A;  3EGX A;  1NPH A;  1DEJ S;  1SVR A;  5KYY B;  3EH2 A;  2FGH A;  1Q8G A;  3EG9 B;  1ESV S;  1SVQ A;  1T2L A;  3EFO B;  1M2O A;  2NUP B;  1T3Y A;  1M2V A;  3CJC G;  1F7S A;  1C0G S;  1C0F S;  4CBX G;  2XF1 A;  1TVJ A;  1WNJ A;  5KYU B;  3CI5 G;  1AK7 A;  4S10 C;  4KEF A;  2FF3 A;  2MV2 A;  1COF A;  1D4X G;  3DAW B;  2D8B A;  5KYY A;  1X67 A;  3EGD B;  2L72 A;  4PKH B;  1PCX A;  2VAC A;  2VIK A;  2FF6 G;  2XFA A;  3FG6 A;  3A5L S;  3FG7 A;  4PKG G;  3Q2B A;  3A5M S;  5A1M A;  2LJ8 A;  5HVK D;  1MDU A;  4KEE A;  5KYW A;  1AHQ A;  1PD0 A;  5FAF A;  1D0N A;  1P8X A;  1NM1 G;  1V6F A;  4CBU G;  2QTV A;  5KYU A;  3A5O S;  4PKI G;  4LIZ A;  1KCQ A;  1HQZ 1;  2FH1 A;  1EQY S;  5KYX A;  1M4J A;  2LXX A;  2NUT B;  4BEX 1;  3FFN A;  3EGX B;  1WFS A;  2MP4 A;  1H1V G;  3CIP G;  3EGD A;  4JD2 H;  4CBW G;  3EG9 A;  1P8Z G;  2MOT A;  3DA7 A;  3EFO A;  1T44 G;  1CNU A;  2NUP A;  1J72 A;  5L6W C;  1M2V B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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