2FH3A

C-terminal half of gelsolin soaked in low calcium at ph 8
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
330
structure length
321
Chain Sequence
MDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDTPITVVKQGFEPPSFVGWFLGWDDDYW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Calcium ion exchange in crystalline gelsolin
pubmed doi rcsb
molecule tags Contractile protein
source organism Homo sapiens
molecule keywords Gelsolin
total genus 92
structure length 321
sequence length 330
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2005-12-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fh3A01
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fh3A03
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fh3A02
1P8XA 3FG7A 2MV2A 2FF6G 5IVUA 1PCXA 1WNJA 2LJ8A 3EGXB 1MDUA 2MP4A 3FG6A 5KYWA 5KYUB 1M2VB 1CNUA 1TVJA 1NM1G 1SVRA 5HVKB 1ESVS 2VILA 4KEFA 1NPHA 1SVYA 2FGHA 4LIZA 2NUTA 1WFSA 5KYXA 1D4XG 2XFAA 1WM4A 3EG9B 2MOTA 1F7SA 5FAFA 1AHQA 3FFKA 4PKGG 1T44G 4JD2H 1NMDG 1COFA 1T3YA 2FH2A 3CI5G 3L50A 1SVQA 1PD1A 3FFNA 2FH3A 2FH1A 5A1MA 4Z94G 2NUPA 2W0IA 3CJBG 2LXXA 3EGDA 3CJCG 1P8ZG 1DEJS 3EH2A 2FF3A 5KYYA 3TU5B 4S10C 2FH4A 5KYWB 5KYNA 2LLFA 2XF1A 2HD7A 2QTVA 4CBUG 4CBWG 1EQYS 2NUTB 5KYXB 1C0FS 1AK6A 1T3XA 3EH1A 1QPVA 1M2OA 1J72A 1M4JA 1VKKA 5KYUA 1YAGG 2D8BA 4PKHB 4BEX1 5HVKD 3CIPG 3EFOA 1RGIG 1Q8GA 1D0NA 3A5OS 3EG9A 1JHWA 2VIKA 1TMWA 2I2QA 1VFQA 3A5MS 1KCQA 1T2LA 5DD2A 1Q8XA 1C0GS 2NUPB 1NLVG 1UDMA 4KEEA 3EGDB 5L6WC 3EFOB 3A5NS 3EGXA 2L72A 4PKIG 4CBXG 1YVNG 2KVKA 4KEDA 5KYYB 1HQZ1 1M2VA 1V6FA 3A5LS 2VACA 5FAEA 1H1VG 3DAWB 3Q2BA 1AK7A 1CFYA 1PD0A 1X67A
chains in the Genus database with same CATH superfamily
1P8XA 3FG7A 2MV2A 2FF6G 5IVUA 1PCXA 1WNJA 2LJ8A 3EGXB 1MDUA 2MP4A 3FG6A 5KYWA 5KYUB 1M2VB 1CNUA 1TVJA 1NM1G 1SVRA 5HVKB 1ESVS 2VILA 4KEFA 1NPHA 1SVYA 2FGHA 4LIZA 2NUTA 1WFSA 5KYXA 3DA7A 1D4XG 2XFAA 1WM4A 3EG9B 2MOTA 1F7SA 5FAFA 1AHQA 3FFKA 4PKGG 1T44G 4JD2H 1NMDG 1COFA 1T3YA 2FH2A 3CI5G 3L50A 1SVQA 1PD1A 3FFNA 2FH3A 2FH1A 5A1MA 4Z94G 2NUPA 2W0IA 3CJBG 2LXXA 3EGDA 3CJCG 1P8ZG 1DEJS 3EH2A 2FF3A 5KYYA 3TU5B 4S10C 2FH4A 5KYWB 5KYNA 2LLFA 2XF1A 2HD7A 2QTVA 4CBUG 4CBWG 1EQYS 2NUTB 5KYXB 1C0FS 1AK6A 1T3XA 3EH1A 1QPVA 1M2OA 1J72A 1M4JA 1VKKA 5KYUA 1YAGG 2D8BA 4PKHB 4BEX1 5HVKD 3CIPG 3EFOA 1RGIG 1Q8GA 1D0NA 3A5OS 3EG9A 1JHWA 2VIKA 1TMWA 2I2QA 1VFQA 3A5MS 1KCQA 1T2LA 5DD2A 1Q8XA 1C0GS 2NUPB 1NLVG 1UDMA 4KEEA 3EGDB 5L6WC 3EFOB 3A5NS 3EGXA 2L72A 4PKIG 4CBXG 1YVNG 2KVKA 4KEDA 5KYYB 1HQZ1 1M2VA 1V6FA 3A5LS 2VACA 5FAEA 1H1VG 3DAWB 3Q2BA 1AK7A 1CFYA 1PD0A 1X67A
chains in the Genus database with same CATH topology
1P8XA 3FG7A 2MV2A 2FF6G 5IVUA 1PCXA 1WNJA 2LJ8A 3EGXB 1MDUA 2MP4A 3FG6A 5KYWA 5KYUB 1M2VB 1CNUA 1TVJA 1NM1G 1SVRA 5HVKB 1ESVS 2VILA 4KEFA 1NPHA 1SVYA 2FGHA 4LIZA 2NUTA 1WFSA 5KYXA 3DA7A 1D4XG 2XFAA 1WM4A 3EG9B 2MOTA 1F7SA 5FAFA 1AHQA 3FFKA 4PKGG 1T44G 4JD2H 1NMDG 1COFA 1T3YA 2FH2A 3CI5G 3L50A 1SVQA 1PD1A 3FFNA 2FH3A 2FH1A 5A1MA 4Z94G 2NUPA 2W0IA 3CJBG 2LXXA 3EGDA 3CJCG 1P8ZG 1DEJS 3EH2A 2FF3A 5KYYA 3TU5B 4S10C 2FH4A 5KYWB 5KYNA 2LLFA 2XF1A 2HD7A 2QTVA 4CBUG 4CBWG 1EQYS 2NUTB 5KYXB 1C0FS 1AK6A 1T3XA 3EH1A 1QPVA 1M2OA 1J72A 1M4JA 1VKKA 5KYUA 1YAGG 2D8BA 4PKHB 4BEX1 5HVKD 3CIPG 3EFOA 1RGIG 1Q8GA 1D0NA 3A5OS 3EG9A 1JHWA 2VIKA 1TMWA 2I2QA 1VFQA 3A5MS 1KCQA 1T2LA 5DD2A 1Q8XA 1C0GS 2NUPB 1NLVG 1UDMA 4KEEA 3EGDB 5L6WC 3EFOB 3A5NS 3EGXA 2L72A 4PKIG 4CBXG 1YVNG 2KVKA 4KEDA 5KYYB 1HQZ1 1M2VA 1V6FA 3A5LS 2VACA 5FAEA 1H1VG 3DAWB 3Q2BA 1AK7A 1CFYA 1PD0A 1X67A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1P8X A;  3FG7 A;  2MV2 A;  2FF6 G;  5IVU A;  1PCX A;  1WNJ A;  2LJ8 A;  3EGX B;  1MDU A;  2MP4 A;  3FG6 A;  5KYW A;  5KYU B;  1M2V B;  1CNU A;  1TVJ A;  1NM1 G;  1SVR A;  5HVK B;  1ESV S;  2VIL A;  4KEF A;  1NPH A;  1SVY A;  2FGH A;  4LIZ A;  2NUT A;  1WFS A;  5KYX A;  1D4X G;  2XFA A;  1WM4 A;  3EG9 B;  2MOT A;  1F7S A;  5FAF A;  1AHQ A;  3FFK A;  4PKG G;  1T44 G;  4JD2 H;  1NMD G;  1COF A;  1T3Y A;  2FH2 A;  3CI5 G;  3L50 A;  1SVQ A;  1PD1 A;  3FFN A;  2FH3 A;  2FH1 A;  5A1M A;  4Z94 G;  2NUP A;  2W0I A;  3CJB G;  2LXX A;  3EGD A;  3CJC G;  1P8Z G;  1DEJ S;  3EH2 A;  2FF3 A;  5KYY A;  3TU5 B;  4S10 C;  2FH4 A;  5KYW B;  5KYN A;  2LLF A;  2XF1 A;  2HD7 A;  2QTV A;  4CBU G;  4CBW G;  1EQY S;  2NUT B;  5KYX B;  1C0F S;  1AK6 A;  1T3X A;  3EH1 A;  1QPV A;  1M2O A;  1J72 A;  1M4J A;  1VKK A;  5KYU A;  1YAG G;  2D8B A;  4PKH B;  4BEX 1;  5HVK D;  3CIP G;  3EFO A;  1RGI G;  1Q8G A;  1D0N A;  3A5O S;  3EG9 A;  1JHW A;  2VIK A;  1TMW A;  2I2Q A;  1VFQ A;  3A5M S;  1KCQ A;  1T2L A;  5DD2 A;  1Q8X A;  1C0G S;  2NUP B;  1NLV G;  1UDM A;  4KEE A;  3EGD B;  5L6W C;  3EFO B;  3A5N S;  3EGX A;  2L72 A;  4PKI G;  4CBX G;  1YVN G;  2KVK A;  4KED A;  5KYY B;  1HQZ 1;  1M2V A;  1V6F A;  3A5L S;  2VAC A;  5FAE A;  1H1V G;  3DAW B;  3Q2B A;  1AK7 A;  1CFY A;  1PD0 A;  1X67 A; 
#chains in the Genus database with same CATH topology
 1P8X A;  3FG7 A;  2MV2 A;  2FF6 G;  5IVU A;  1PCX A;  1WNJ A;  2LJ8 A;  3EGX B;  1MDU A;  2MP4 A;  3FG6 A;  5KYW A;  5KYU B;  1M2V B;  1CNU A;  1TVJ A;  1NM1 G;  1SVR A;  5HVK B;  1ESV S;  2VIL A;  4KEF A;  1NPH A;  1SVY A;  2FGH A;  4LIZ A;  2NUT A;  1WFS A;  5KYX A;  3DA7 A;  1D4X G;  2XFA A;  1WM4 A;  3EG9 B;  2MOT A;  1F7S A;  5FAF A;  1AHQ A;  3FFK A;  4PKG G;  1T44 G;  4JD2 H;  1NMD G;  1COF A;  1T3Y A;  2FH2 A;  3CI5 G;  3L50 A;  1SVQ A;  1PD1 A;  3FFN A;  2FH3 A;  2FH1 A;  5A1M A;  4Z94 G;  2NUP A;  2W0I A;  3CJB G;  2LXX A;  3EGD A;  3CJC G;  1P8Z G;  1DEJ S;  3EH2 A;  2FF3 A;  5KYY A;  3TU5 B;  4S10 C;  2FH4 A;  5KYW B;  5KYN A;  2LLF A;  2XF1 A;  2HD7 A;  2QTV A;  4CBU G;  4CBW G;  1EQY S;  2NUT B;  5KYX B;  1C0F S;  1AK6 A;  1T3X A;  3EH1 A;  1QPV A;  1M2O A;  1J72 A;  1M4J A;  1VKK A;  5KYU A;  1YAG G;  2D8B A;  4PKH B;  4BEX 1;  5HVK D;  3CIP G;  3EFO A;  1RGI G;  1Q8G A;  1D0N A;  3A5O S;  3EG9 A;  1JHW A;  2VIK A;  1TMW A;  2I2Q A;  1VFQ A;  3A5M S;  1KCQ A;  1T2L A;  5DD2 A;  1Q8X A;  1C0G S;  2NUP B;  1NLV G;  1UDM A;  4KEE A;  3EGD B;  5L6W C;  3EFO B;  3A5N S;  3EGX A;  2L72 A;  4PKI G;  4CBX G;  1YVN G;  2KVK A;  4KED A;  5KYY B;  1HQZ 1;  1M2V A;  1V6F A;  3A5L S;  2VAC A;  5FAE A;  1H1V G;  3DAW B;  3Q2B A;  1AK7 A;  1CFY A;  1PD0 A;  1X67 A; 
#chains in the Genus database with same CATH homology
 1P8X A;  3FG7 A;  2MV2 A;  2FF6 G;  5IVU A;  1PCX A;  1WNJ A;  2LJ8 A;  3EGX B;  1MDU A;  2MP4 A;  3FG6 A;  5KYW A;  5KYU B;  1M2V B;  1CNU A;  1TVJ A;  1NM1 G;  1SVR A;  5HVK B;  1ESV S;  2VIL A;  4KEF A;  1NPH A;  1SVY A;  2FGH A;  4LIZ A;  2NUT A;  1WFS A;  5KYX A;  3DA7 A;  1D4X G;  2XFA A;  1WM4 A;  3EG9 B;  2MOT A;  1F7S A;  5FAF A;  1AHQ A;  3FFK A;  4PKG G;  1T44 G;  4JD2 H;  1NMD G;  1COF A;  1T3Y A;  2FH2 A;  3CI5 G;  3L50 A;  1SVQ A;  1PD1 A;  3FFN A;  2FH3 A;  2FH1 A;  5A1M A;  4Z94 G;  2NUP A;  2W0I A;  3CJB G;  2LXX A;  3EGD A;  3CJC G;  1P8Z G;  1DEJ S;  3EH2 A;  2FF3 A;  5KYY A;  3TU5 B;  4S10 C;  2FH4 A;  5KYW B;  5KYN A;  2LLF A;  2XF1 A;  2HD7 A;  2QTV A;  4CBU G;  4CBW G;  1EQY S;  2NUT B;  5KYX B;  1C0F S;  1AK6 A;  1T3X A;  3EH1 A;  1QPV A;  1M2O A;  1J72 A;  1M4J A;  1VKK A;  5KYU A;  1YAG G;  2D8B A;  4PKH B;  4BEX 1;  5HVK D;  3CIP G;  3EFO A;  1RGI G;  1Q8G A;  1D0N A;  3A5O S;  3EG9 A;  1JHW A;  2VIK A;  1TMW A;  2I2Q A;  1VFQ A;  3A5M S;  1KCQ A;  1T2L A;  5DD2 A;  1Q8X A;  1C0G S;  2NUP B;  1NLV G;  1UDM A;  4KEE A;  3EGD B;  5L6W C;  3EFO B;  3A5N S;  3EGX A;  2L72 A;  4PKI G;  4CBX G;  1YVN G;  2KVK A;  4KED A;  5KYY B;  1HQZ 1;  1M2V A;  1V6F A;  3A5L S;  2VAC A;  5FAE A;  1H1V G;  3DAW B;  3Q2B A;  1AK7 A;  1CFY A;  1PD0 A;  1X67 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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