2FTSA

Crystal structure of the glycine receptor-gephyrin complex
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
419
structure length
419
Chain Sequence
MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Deciphering the structural framework of glycine receptor anchoring by gephyrin.
pubmed doi rcsb
molecule tags Structural protein
source organism Rattus norvegicus
molecule keywords gephyrin
total genus 95
structure length 419
sequence length 419
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2006-01-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 2ftsA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 2ftsA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 2ftsA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 2ftsA02
2G2CA 5ERRA 4XCWA 4TK3A 2NROA 5ERSA 1R2KA 2NQSA 5ERTA 2FTSA 4PD1A 3OI9A 2PBQA 4TWGA 2NQKA 2NRPA 2NQQA 4CT8A 5ERQA 4NWOA 3K6AA 4UUXA 1O8QA 2NQUA 1JLJA 4U91A 1T3EA 2F7YA 3MCJA 1Y5EA 2NRSA 4PD0A 4TK1A 5G2SA 1UUXA 1DI7A 3MCIA 3RFQA 4LHBA 1EAVA 1MKZA 1UZ5A 1UUYA 5G2RA 4UUWA 3TCRA 1O8OA 4CTAA 2NQNA 4CT9A 1FC5A 2NQMA 1DI6A 2IS8A 1O8NA 3MCHA 2NQRA 2FU3A 5ERVA 4CTAB 2QQ1A 1G8RA 2F7WA 2X3LA 3IWTA 2NQVA 4UOCA 1IHCA 3PZYA 2G4RA 1G8LA 1WU2A 5ERUA 4TK4A 4U90A 1XI8A 3KBQA
chains in the Genus database with same CATH superfamily
2G2CA 5ERRA 4XCWA 5DMHA 4TK3A 2NROA 5D6GA 5ERSA 1R2KA 2NQSA 5ERTA 2FTSA 4PD1A 3OI9A 2PBQA 4TWGA 2NQKA 2NRPA 2NQQA 4CT8A 5D8HB 5ERQA 4NWOA 3K6AA 4UUXA 1O8QA 2NQUA 1HQMD 1JLJA 4U91A 1T3EA 2F7YA 3MCJA 3JSYA 1Y5EA 2NRSA 4PD0A 4TK1A 5G2SA 1UUXA 4NWBA 1DI7A 3MCIA 3RFQA 4LHBA 1EAVA 1MKZA 1UZ5A 1UUYA 5G2RA 4UUWA 3TCRA 1O8OA 4CTAA 2NQNA 4CT9A 1FC5A 2NQMA 1DI6A 2IS8A 1O8NA 3MCHA 2NQRA 2FU3A 5ERVA 4CTAB 1IW7D 2QQ1A 1G8RA 2F7WA 2X3LA 3DQQA 3IWTA 2NQVA 4UOCA 1YZYA 1I6VD 1IHCA 3PZYA 2G4RA 1G8LA 1WU2A 5ERUA 4TK4A 4U90A 1XI8A 3KBQA
chains in the Genus database with same CATH topology
2G2CA 5ERRA 4XCWA 4TK3A 2NROA 5D6GA 5ERSA 1R2KA 2NQSA 5ERTA 2FTSA 4PD1A 3OI9A 2PBQA 4TWGA 2NQKA 2NRPA 2NQQA 4CT8A 5D8HB 5ERQA 4NWOA 3K6AA 4UUXA 1O8QA 2NQUA 1HQMD 1JLJA 4U91A 1T3EA 2F7YA 3MCJA 3JSYA 1Y5EA 2NRSA 4PD0A 4TK1A 5G2SA 1UUXA 4NWBA 1DI7A 3MCIA 3RFQA 4LHBA 1EAVA 1MKZA 1UZ5A 1UUYA 5G2RA 4UUWA 3TCRA 1O8OA 4CTAA 2NQNA 4CT9A 1FC5A 2NQMA 1DI6A 2IS8A 1O8NA 3MCHA 2NQRA 2FU3A 5ERVA 4CTAB 1IW7D 2QQ1A 1G8RA 2F7WA 2X3LA 3IWTA 2NQVA 4UOCA 1I6VD 1IHCA 3PZYA 2G4RA 1G8LA 1WU2A 5ERUA 4TK4A 4U90A 1XI8A 3KBQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2G2C A;  5ERR A;  4XCW A;  4TK3 A;  2NRO A;  5ERS A;  1R2K A;  2NQS A;  5ERT A;  2FTS A;  4PD1 A;  3OI9 A;  2PBQ A;  4TWG A;  2NQK A;  2NRP A;  2NQQ A;  4CT8 A;  5ERQ A;  4NWO A;  3K6A A;  4UUX A;  1O8Q A;  2NQU A;  1JLJ A;  4U91 A;  1T3E A;  2F7Y A;  3MCJ A;  1Y5E A;  2NRS A;  4PD0 A;  4TK1 A;  5G2S A;  1UUX A;  1DI7 A;  3MCI A;  3RFQ A;  4LHB A;  1EAV A;  1MKZ A;  1UZ5 A;  1UUY A;  5G2R A;  4UUW A;  3TCR A;  1O8O A;  4CTA A;  2NQN A;  4CT9 A;  1FC5 A;  2NQM A;  1DI6 A;  2IS8 A;  1O8N A;  3MCH A;  2NQR A;  2FU3 A;  5ERV A;  4CTA B;  2QQ1 A;  1G8R A;  2F7W A;  2X3L A;  3IWT A;  2NQV A;  4UOC A;  1IHC A;  3PZY A;  2G4R A;  1G8L A;  1WU2 A;  5ERU A;  4TK4 A;  4U90 A;  1XI8 A;  3KBQ A; 
#chains in the Genus database with same CATH topology
 2G2C A;  5ERR A;  4XCW A;  5DMH A;  4TK3 A;  2NRO A;  5D6G A;  5ERS A;  1R2K A;  2NQS A;  5ERT A;  2FTS A;  4PD1 A;  3OI9 A;  2PBQ A;  4TWG A;  2NQK A;  2NRP A;  2NQQ A;  4CT8 A;  5D8H B;  5ERQ A;  4NWO A;  3K6A A;  4UUX A;  1O8Q A;  2NQU A;  1HQM D;  1JLJ A;  4U91 A;  1T3E A;  2F7Y A;  3MCJ A;  3JSY A;  1Y5E A;  2NRS A;  4PD0 A;  4TK1 A;  5G2S A;  1UUX A;  4NWB A;  1DI7 A;  3MCI A;  3RFQ A;  4LHB A;  1EAV A;  1MKZ A;  1UZ5 A;  1UUY A;  5G2R A;  4UUW A;  3TCR A;  1O8O A;  4CTA A;  2NQN A;  4CT9 A;  1FC5 A;  2NQM A;  1DI6 A;  2IS8 A;  1O8N A;  3MCH A;  2NQR A;  2FU3 A;  5ERV A;  4CTA B;  1IW7 D;  2QQ1 A;  1G8R A;  2F7W A;  2X3L A;  3DQQ A;  3IWT A;  2NQV A;  4UOC A;  1YZY A;  1I6V D;  1IHC A;  3PZY A;  2G4R A;  1G8L A;  1WU2 A;  5ERU A;  4TK4 A;  4U90 A;  1XI8 A;  3KBQ A; 
#chains in the Genus database with same CATH homology
 2G2C A;  5ERR A;  4XCW A;  4TK3 A;  2NRO A;  5D6G A;  5ERS A;  1R2K A;  2NQS A;  5ERT A;  2FTS A;  4PD1 A;  3OI9 A;  2PBQ A;  4TWG A;  2NQK A;  2NRP A;  2NQQ A;  4CT8 A;  5D8H B;  5ERQ A;  4NWO A;  3K6A A;  4UUX A;  1O8Q A;  2NQU A;  1HQM D;  1JLJ A;  4U91 A;  1T3E A;  2F7Y A;  3MCJ A;  3JSY A;  1Y5E A;  2NRS A;  4PD0 A;  4TK1 A;  5G2S A;  1UUX A;  4NWB A;  1DI7 A;  3MCI A;  3RFQ A;  4LHB A;  1EAV A;  1MKZ A;  1UZ5 A;  1UUY A;  5G2R A;  4UUW A;  3TCR A;  1O8O A;  4CTA A;  2NQN A;  4CT9 A;  1FC5 A;  2NQM A;  1DI6 A;  2IS8 A;  1O8N A;  3MCH A;  2NQR A;  2FU3 A;  5ERV A;  4CTA B;  1IW7 D;  2QQ1 A;  1G8R A;  2F7W A;  2X3L A;  3IWT A;  2NQV A;  4UOC A;  1I6V D;  1IHC A;  3PZY A;  2G4R A;  1G8L A;  1WU2 A;  5ERU A;  4TK4 A;  4U90 A;  1XI8 A;  3KBQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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