2G00L

Factor xa in complex with the inhibitor 3-(6-(2'-((dimethylamino)methyl)-4-biphenylyl)-7-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1h-pyrazolo[3,4-c]pyridin-1-yl)benzamide
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
52
structure length
52
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of potent, efficacious, and orally bioavailable inhibitors of blood coagulation factor Xa with neutral P1 moieties.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Coagulation factor X
total genus 12
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2006-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2g00L00
2WYGB 3ZYIB 1JV2B 1NFUB 2MHPA 2VJ3A 4NA9L 4X8TL 5JBCE 1JL9A 2WPLE 4CUEA 1EGFA 1IQKL 1KLOA 1U67A 4D0EA 2WFTA 3POYA 4NG9L 1HAFA 3SOVA 2W2NE 4Y71B 3ZYGA 3F1SB 2KL7A 3N8YA 1WHEA 3HO3A 1HCGB 3BT2A 2WPHE 2I9BA 1NFWB 1YUKB 2BOXA 2PUQL 2MGPA 2P26A 4G1MB 1XKAL 3ELAL 3V65B 2RHPA 4JZEL 2VWNL 1EQGA 5K0HB 3N8VA 3CS7L 1FSBA 2KV4A 1MQ6L 1NT0A 3QH0A 4Y7BB 2BQ6A 1BF9A 2KB9A 1A3PA 5F19A 5CKNA 1DX5I 1XFEA 2YGPA 3KQEL 3LTFB 3KQBL 1IQLL 1AUTL 3HO4A 2P3TA 2J34B 1F7EA 1G1TA 1N7DA 1UZPA 3ASIA 2PHBB 4JYUL 5IKVA 2UWPB 2P95L 1P0SL 3HPTA 4AQTA 1EPHA 4X8VL 1JBUL 3QMOA 1YUFA 2Q1JB 1RFNB 1FF7A 4JZDL 4LORA 2Y82B 4M10A 1YGCL 1CEJA 2WPME 2P94L 4BXWA 2WG3C 2Y81B 2Y5FL 3KK6A 1L5GB 3TZIA 5IKQA 3KL6B 4RS0A 5L30L 1HJ7A 2BQWA 3HS5A 2K2TA 5IKTA 4RRWA 1B9WA 2BMGA 3FFGL 2BOUA 1Q4GA 4C16A 3BT1A 4X8UL 2MGRA 4Y6DB 2WPIE 3N8XA 3DEMA 5EGMB 1IOEL 1NZIA 2Y38A 3TGFA 2WPJE 3TH3L 2XBVL 4CUFA 1U8CB 5L2YL 5JB9E 1HT8A 2CJIB 3N8WA 1WHFA 1PRHA 2W3IB 4RRXA 1IJQA 1PXXA 1EPJA 3ZYJB 4MMYB 3FCSB 1HT5A 2UWOB 2BO2A 3TBDA 1K37A 4XL1A 2WPKE 1ATDA 4BDXA 1FAXL 1KLIL 5FDQA 3KQDL 1TPGA 4CUDA 1OB1C 2J2UB 1LPZA 2NPRA 4M11A 4BTTA 5CKMA 5JB8E 4ISIL 4ZXYL 2FLBL 1CX2A 2J94B 5CISA 1IQHL 1EQHA 1APOA 1UZKA 1J9CL 4PH9A 2M74A 4A7IA 3IJEB 3TK5B 1EPGA 2J4IB 2YGOA 2Y5GL 4JZFL 2XC0L 2K2SB 1M1XB 2W2OE 3N8ZA 3F6UL 3GCXE 1EBVA 2I9AA 1IP0A 2DDUA 4OTYA 2AYLA 5KN5C 1MQ5L 3V64C 4X8SL 1IQIL 1L3YA 2TGFA 3C9AC 1IQNL 5JBAE 2EI7B 1WU1B 2W2ME 2XBXL 5IKRA 2RNLA 3KQCL 3LN1A 2W2QE 1TOZA 1NFYB 2PR3B 1X7AL 2VVCK 3LTGD 4ZAEB 3CFWA 1TLEA 5KIRA 2Y80B 3MDLA 4D0FA 1GK5A 2Y5HL 3HS7A 2XC5L 1KLJL 3U7UG 4Y79B 1ATAA 1EPIA 2VWLL 1G1QA 1FJSL 1UZJA 4YT6L 2GD4A 3U73A 2JKHL 1DIYA 3LAQA 4NGAL 1I0UA 4RRZA 5F1AA 1PFXL 3QCWA 4BDWA 1FFMA 1Z6EL 2OYUP 3CA7A 2FZZL 2ADXA 1ATEA 4Y76B 2P93L 2Y7XB 3EGFA 6COXA 2VVVL 1CVWL 2W26B 3OLUA 3M36L 1N1IA 2WFXB 1IQJL 1QFKL 4BTUA 3SOQA 3LIWB 3N8WB 2RA0L 3NTBA 1CQEA 5L2ZL 2WG4B 1G2MB 5JBBE 3IITB 2FD6A 1V3XB 1KSNB 1NQLB 2EI6B 4Z6AL 2W2PE 1IOXA 1EMOA 3FBYA 3NTGA 3OLTA 4E1GA 3N8YB 5JVZA 1ATBA 2P16L 1NPEB 1DDXA 1YUGA 4RUTA 4XLWA 5JW1A 1YO8A 2F9BL 5E8DA 4O1ZA 2BZ6L 1EZQB 3K9XA 3H5CB 1LPGA 2VWOL 4ZHAB 1XDTR 1O5DL 2WYJB 1ADXA 1IQGL 5I46L 1K36A 1XKBA 2UWLB 2W86A 1FE2A 2W3KB 1W8BL 3R05A 4RRYA 1G1SA 3PGHA 4COXA 1HRFA 2VH0B 3LC3B 1Z6CA 3NJPC 3CENL 1IVOC 3Q7DA 1LQDA 4TGFA 3LC5B 1DQBA 1G1RA 4ZXXL 2XBWL 1DVAL 1F0SB 1URKA 1P9JA 5COXA 3SW2A 2BQ7A 5CKQA 3GCWE 4LMFA 3SOBB 1EAIC 2B7DL 4Z0LA 1LPKA 4BTIA 3P5BL 3GISX 1IQFL 1EMNA 3TK6B 1IQML 3ENSA 4MMZB 2BOKL 2G00L 1IQEL 4YT7L 1ZAQA 2BOHA 3HO5A 2FLGA 2Y7ZB 4JYVL 1IGXA 2H9EL 3HS6A 1APQA 4ISHL 4BXSA 1CCVA 4ZH8B 2XC4L 1HAEA 1MOXC 2P3FN 3LN0A 1G2LB 2OYEP 3M37L 1HX2A 2P3FL 1LMJA 1CCFA 2P28B 2D1JB 4OTJA 4CSYA 4FM5A 3NT1A 1UZQA 1NFXB 2J95B 2J38B 1W7XL 5JVYA 1FAKL 3RR3A 1COUA 1KIGL 2VH6B 3MQEA 4O02B 3KCGL 1HZ8A 1F0RB 2VWMK 3KRKA 4Y7AB 4D90A 4XBMA 2EI8B 4Z0KB 1SZBA 3BPSE 4MMXB 2P3UA 2XBYL 2VVUL 3Q3KB 1CVUA 2FLRL 1C5MF 1PGEA 4YZUB 1HREA 1F7MA 1IGZA 1PTHA
chains in the Genus database with same CATH superfamily
2WYGB 3ZYIB 1JV2B 1NFUB 2MHPA 2VJ3A 4NA9L 4X8TL 5JBCE 1JL9A 2WPLE 4CUEA 1EGFA 1IQKL 1KLOA 1U67A 4D0EA 2WFTA 3POYA 4NG9L 1HAFA 3SOVA 2W2NE 4Y71B 3ZYGA 3F1SB 2KL7A 3N8YA 2YGQA 2BT8A 1WHEA 4GU4A 3HO3A 1HCGB 3BT2A 2HORA 2WPHE 2I9BA 1NFWB 1YUKB 2BOXA 2PUQL 2MGPA 2P26A 4G1MB 1XKAL 3ELAL 3V65B 2RHPA 4JZEL 2VWNL 1EQGA 5K0HB 3N8VA 3CS7L 1FSBA 2KV4A 1MQ6L 1NT0A 3QH0A 4Y7BB 2BQ6A 1BF9A 2KB9A 1A3PA 5F19A 5CKNA 1DX5I 1XFEA 2YGPA 3KQEL 3LTFB 3KQBL 1IQLL 1AUTL 3HO4A 2P3TA 2J34B 1F7EA 1G1TA 1N7DA 1UZPA 3ASIA 2PHBB 4JYUL 5IKVA 2UWPB 2P95L 1P0SL 3HPTA 4AQTA 1EPHA 4X8VL 1JBUL 3QMOA 1YUFA 2Q1JB 1RFNB 1FF7A 4JZDL 4LORA 2Y82B 4M10A 1YGCL 1CEJA 2WPME 2P94L 4BXWA 2WG3C 2Y81B 2Y5FL 3KK6A 1L5GB 3TZIA 5IKQA 3KL6B 4RS0A 5L30L 2H9EC 1HJ7A 2BQWA 3HS5A 2K2TA 5IKTA 4RRWA 1B9WA 2BMGA 3FFGL 2BOUA 1Q4GA 4C16A 3BT1A 1LMMA 4X8UL 2MGRA 4Y6DB 2HOXA 2WPIE 3N8XA 3DEMA 4A94C 5EGMB 1IOEL 1NZIA 2Y38A 3TGFA 2WPJE 3TH3L 2XBVL 4CUFA 1U8CB 5L2YL 5JB9E 1HT8A 2CJIB 3N8WA 1WHFA 1PRHA 2W3IB 4RRXA 1IJQA 1PXXA 1EPJA 3ZYJB 4MMYB 3FCSB 1HT5A 2UWOB 2BO2A 3TBDA 1K37A 4XL1A 2WPKE 1ATDA 4BDXA 1FAXL 1KLIL 5FDQA 3KQDL 1TPGA 4CUDA 1OB1C 2J2UB 1LPZA 2NPRA 4M11A 4BTTA 5CKMA 5JB8E 4ISIL 4ZXYL 2FLBL 1CX2A 2J94B 5CISA 1IQHL 1EQHA 1APOA 1UZKA 1J9CL 4PH9A 2M74A 4A7IA 3IJEB 3TK5B 1EPGA 2J4IB 2YGOA 2Y5GL 4JZFL 2XC0L 2K2SB 1M1XB 2W2OE 3N8ZA 3F6UL 3GCXE 1EBVA 2I9AA 1IP0A 2DDUA 4OTYA 2AYLA 5KN5C 1MQ5L 3V64C 4X8SL 1IQIL 1L3YA 2TGFA 3C9AC 1IQNL 5JBAE 2EI7B 1WU1B 2KNIA 2W2ME 2XBXL 5IKRA 2RNLA 3KQCL 3LN1A 2W2QE 1TOZA 1NFYB 2PR3B 1X7AL 2VVCK 3LTGD 4ZAEB 3CFWA 1TLEA 5KIRA 2Y80B 3MDLA 4D0FA 1GK5A 2Y5HL 3HS7A 2XC5L 2VRSA 1KLJL 3U7UG 4Y79B 1ATAA 1EPIA 2VWLL 1G1QA 1FJSL 1UZJA 4YT6L 2GD4A 3U73A 2JKHL 1V1HA 1DIYA 3LAQA 4NGAL 1I0UA 4RRZA 5F1AA 1PFXL 3QCWA 4BDWA 1FFMA 1Z6EL 2OYUP 3CA7A 2FZZL 2ADXA 1ATEA 4Y76B 2P93L 2Y7XB 1QIUA 3EGFA 6COXA 2VVVL 1CVWL 2W26B 3OLUA 3M36L 1N1IA 2WFXB 1IQJL 1QFKL 4BTUA 3SOQA 3LIWB 3N8WB 2RA0L 3NTBA 1CQEA 5L2ZL 2WG4B 1G2MB 5JBBE 3IITB 2FD6A 1V3XB 1KSNB 1NQLB 2EI6B 4Z6AL 2W2PE 1IOXA 1EMOA 3FBYA 3NTGA 3OLTA 4E1GA 3N8YB 5JVZA 1ATBA 2P16L 1NPEB 2BT7A 1DDXA 1YUGA 4RUTA 4XLWA 5JW1A 1YO8A 2F9BL 5E8DA 4O1ZA 2BZ6L 1EZQB 3K9XA 3H5CB 1LPGA 2VWOL 4ZHAB 1XDTR 1O5DL 2WYJB 1ADXA 1IQGL 5I46L 1K36A 1XKBA 2UWLB 2W86A 2JJLA 1FE2A 2W3KB 1W8BL 3R05A 4RRYA 1G1SA 3PGHA 4COXA 1HRFA 2VH0B 3LC3B 1Z6CA 3NJPC 3CENL 1IVOC 3Q7DA 1LQDA 4TGFA 3LC5B 1DQBA 1G1RA 4ZXXL 1LK9A 2XBWL 1DVAL 1F0SB 1URKA 1P9JA 5COXA 3SW2A 2BQ7A 5CKQA 3GCWE 4LMFA 3SOBB 1EAIC 2B7DL 4Z0LA 1LPKA 4BTIA 3P5BL 3GISX 1IQFL 2WZPP 1EMNA 3TK6B 1KKEA 1IQML 3ENSA 4MMZB 2BOKL 2G00L 1IQEL 4YT7L 1ZAQA 2BOHA 3HO5A 2FLGA 2Y7ZB 4JYVL 1IGXA 2H9EL 3HS6A 1APQA 4ISHL 4BXSA 1CCVA 4ZH8B 2XC4L 1HAEA 1MOXC 2P3FN 3LN0A 1G2LB 2OYEP 3M37L 1HX2A 2P3FL 1LMJA 1CCFA 2P28B 2D1JB 1V1IA 4OTJA 4CSYA 4FM5A 3NT1A 1UZQA 1NFXB 2J95B 2J38B 1W7XL 5JVYA 1FAKL 3RR3A 1COUA 1KIGL 2VH6B 3MQEA 4O02B 3KCGL 1HZ8A 1F0RB 2VWMK 4GU3A 3KRKA 4Y7AB 4D90A 4XBMA 2EI8B 4Z0KB 1SZBA 3BPSE 4MMXB 2P3UA 2XBYL 2BSFA 2VVUL 3Q3KB 3S6XA 1CVUA 2FLRL 1C5MF 1PGEA 4YZUB 1HREA 1F7MA 1IGZA 1PTHA
chains in the Genus database with same CATH topology
2WYGB 3ZYIB 1JV2B 1NFUB 2MHPA 2VJ3A 4NA9L 4X8TL 5JBCE 1JL9A 2WPLE 4CUEA 1EGFA 1IQKL 1KLOA 1U67A 4D0EA 2WFTA 3POYA 4NG9L 1HAFA 3SOVA 2W2NE 4Y71B 3ZYGA 3F1SB 2KL7A 3N8YA 2YGQA 1WHEA 3HO3A 1HCGB 3BT2A 2WPHE 2I9BA 1NFWB 1YUKB 2BOXA 2PUQL 2MGPA 2P26A 4G1MB 1XKAL 3ELAL 3V65B 2RHPA 4JZEL 2VWNL 1EQGA 5K0HB 3N8VA 3CS7L 1FSBA 2KV4A 1MQ6L 1NT0A 3QH0A 4Y7BB 2BQ6A 1BF9A 2KB9A 1A3PA 5F19A 5CKNA 1DX5I 1XFEA 2YGPA 3KQEL 3LTFB 3KQBL 1IQLL 1AUTL 3HO4A 2P3TA 2J34B 1F7EA 1G1TA 1N7DA 1UZPA 3ASIA 2PHBB 4JYUL 5IKVA 2UWPB 2P95L 1P0SL 3HPTA 4AQTA 1EPHA 4X8VL 1JBUL 3QMOA 1YUFA 2Q1JB 1RFNB 1FF7A 4JZDL 4LORA 2Y82B 4M10A 1YGCL 1CEJA 2WPME 2P94L 4BXWA 2WG3C 2Y81B 2Y5FL 3KK6A 1L5GB 3TZIA 5IKQA 3KL6B 4RS0A 5L30L 2H9EC 1HJ7A 2BQWA 3HS5A 2K2TA 5IKTA 4RRWA 1B9WA 2BMGA 3FFGL 2BOUA 1Q4GA 4C16A 3BT1A 1LMMA 4X8UL 2MGRA 4Y6DB 2WPIE 3N8XA 3DEMA 4A94C 5EGMB 1IOEL 1NZIA 2Y38A 3TGFA 2WPJE 3TH3L 2XBVL 4CUFA 1U8CB 5L2YL 5JB9E 1HT8A 2CJIB 3N8WA 1WHFA 1PRHA 2W3IB 4RRXA 1IJQA 1PXXA 1EPJA 3ZYJB 4MMYB 3FCSB 1HT5A 2UWOB 2BO2A 3TBDA 1K37A 4XL1A 2WPKE 1ATDA 4BDXA 1FAXL 1KLIL 5FDQA 3KQDL 1TPGA 4CUDA 1OB1C 2J2UB 1LPZA 2NPRA 4M11A 4BTTA 5CKMA 5JB8E 4ISIL 4ZXYL 2FLBL 1CX2A 2J94B 5CISA 1IQHL 1EQHA 1APOA 1UZKA 1J9CL 4PH9A 2M74A 4A7IA 3IJEB 3TK5B 1EPGA 2J4IB 2YGOA 2Y5GL 4JZFL 2XC0L 2K2SB 1M1XB 2W2OE 3N8ZA 3F6UL 3GCXE 1EBVA 2I9AA 1IP0A 2DDUA 4OTYA 2AYLA 5KN5C 1MQ5L 3V64C 4X8SL 1IQIL 1L3YA 2TGFA 3C9AC 1IQNL 5JBAE 2EI7B 1WU1B 2KNIA 2W2ME 2XBXL 5IKRA 2RNLA 3KQCL 3LN1A 2W2QE 1TOZA 1NFYB 2PR3B 1X7AL 2VVCK 3LTGD 4ZAEB 3CFWA 1TLEA 5KIRA 2Y80B 3MDLA 4D0FA 1GK5A 2Y5HL 3HS7A 2XC5L 1KLJL 3U7UG 4Y79B 1ATAA 1EPIA 2VWLL 1G1QA 1FJSL 1UZJA 4YT6L 2GD4A 3U73A 2JKHL 1DIYA 3LAQA 4NGAL 1I0UA 4RRZA 5F1AA 1PFXL 3QCWA 4BDWA 1FFMA 1Z6EL 2OYUP 3CA7A 2FZZL 2ADXA 1ATEA 4Y76B 2P93L 2Y7XB 3EGFA 6COXA 2VVVL 1CVWL 2W26B 3OLUA 3M36L 1N1IA 2WFXB 1IQJL 1QFKL 4BTUA 3SOQA 3LIWB 3N8WB 2RA0L 3NTBA 1CQEA 5L2ZL 2WG4B 1G2MB 5JBBE 3IITB 2FD6A 1V3XB 1KSNB 1NQLB 2EI6B 4Z6AL 2W2PE 1IOXA 1EMOA 3FBYA 3NTGA 3OLTA 4E1GA 3N8YB 5JVZA 1ATBA 2P16L 1NPEB 1DDXA 1YUGA 4RUTA 4XLWA 5JW1A 1YO8A 2F9BL 5E8DA 4O1ZA 2BZ6L 1EZQB 3K9XA 3H5CB 1LPGA 2VWOL 4ZHAB 1XDTR 1O5DL 2WYJB 1ADXA 1IQGL 5I46L 1K36A 1XKBA 2UWLB 2W86A 1FE2A 2W3KB 1W8BL 3R05A 4RRYA 1G1SA 3PGHA 4COXA 1HRFA 2VH0B 3LC3B 1Z6CA 3NJPC 3CENL 1IVOC 3Q7DA 1LQDA 4TGFA 3LC5B 1DQBA 1G1RA 4ZXXL 2XBWL 1DVAL 1F0SB 1URKA 1P9JA 5COXA 3SW2A 2BQ7A 5CKQA 3GCWE 4LMFA 3SOBB 1EAIC 2B7DL 4Z0LA 1LPKA 4BTIA 3P5BL 3GISX 1IQFL 2WZPP 1EMNA 3TK6B 1IQML 3ENSA 4MMZB 2BOKL 2G00L 1IQEL 4YT7L 1ZAQA 2BOHA 3HO5A 2FLGA 2Y7ZB 4JYVL 1IGXA 2H9EL 3HS6A 1APQA 4ISHL 4BXSA 1CCVA 4ZH8B 2XC4L 1HAEA 1MOXC 2P3FN 3LN0A 1G2LB 2OYEP 3M37L 1HX2A 2P3FL 1LMJA 1CCFA 2P28B 2D1JB 4OTJA 4CSYA 4FM5A 3NT1A 1UZQA 1NFXB 2J95B 2J38B 1W7XL 5JVYA 1FAKL 3RR3A 1COUA 1KIGL 2VH6B 3MQEA 4O02B 3KCGL 1HZ8A 1F0RB 2VWMK 3KRKA 4Y7AB 4D90A 4XBMA 2EI8B 4Z0KB 1SZBA 3BPSE 4MMXB 2P3UA 2XBYL 2VVUL 3Q3KB 3S6XA 1CVUA 2FLRL 1C5MF 1PGEA 4YZUB 1HREA 1F7MA 1IGZA 1PTHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WYG B;  3ZYI B;  1JV2 B;  1NFU B;  2MHP A;  2VJ3 A;  4NA9 L;  4X8T L;  5JBC E;  1JL9 A;  2WPL E;  4CUE A;  1EGF A;  1IQK L;  1KLO A;  1U67 A;  4D0E A;  2WFT A;  3POY A;  4NG9 L;  1HAF A;  3SOV A;  2W2N E;  4Y71 B;  3ZYG A;  3F1S B;  2KL7 A;  3N8Y A;  1WHE A;  3HO3 A;  1HCG B;  3BT2 A;  2WPH E;  2I9B A;  1NFW B;  1YUK B;  2BOX A;  2PUQ L;  2MGP A;  2P26 A;  4G1M B;  1XKA L;  3ELA L;  3V65 B;  2RHP A;  4JZE L;  2VWN L;  1EQG A;  5K0H B;  3N8V A;  3CS7 L;  1FSB A;  2KV4 A;  1MQ6 L;  1NT0 A;  3QH0 A;  4Y7B B;  2BQ6 A;  1BF9 A;  2KB9 A;  1A3P A;  5F19 A;  5CKN A;  1DX5 I;  1XFE A;  2YGP A;  3KQE L;  3LTF B;  3KQB L;  1IQL L;  1AUT L;  3HO4 A;  2P3T A;  2J34 B;  1F7E A;  1G1T A;  1N7D A;  1UZP A;  3ASI A;  2PHB B;  4JYU L;  5IKV A;  2UWP B;  2P95 L;  1P0S L;  3HPT A;  4AQT A;  1EPH A;  4X8V L;  1JBU L;  3QMO A;  1YUF A;  2Q1J B;  1RFN B;  1FF7 A;  4JZD L;  4LOR A;  2Y82 B;  4M10 A;  1YGC L;  1CEJ A;  2WPM E;  2P94 L;  4BXW A;  2WG3 C;  2Y81 B;  2Y5F L;  3KK6 A;  1L5G B;  3TZI A;  5IKQ A;  3KL6 B;  4RS0 A;  5L30 L;  1HJ7 A;  2BQW A;  3HS5 A;  2K2T A;  5IKT A;  4RRW A;  1B9W A;  2BMG A;  3FFG L;  2BOU A;  1Q4G A;  4C16 A;  3BT1 A;  4X8U L;  2MGR A;  4Y6D B;  2WPI E;  3N8X A;  3DEM A;  5EGM B;  1IOE L;  1NZI A;  2Y38 A;  3TGF A;  2WPJ E;  3TH3 L;  2XBV L;  4CUF A;  1U8C B;  5L2Y L;  5JB9 E;  1HT8 A;  2CJI B;  3N8W A;  1WHF A;  1PRH A;  2W3I B;  4RRX A;  1IJQ A;  1PXX A;  1EPJ A;  3ZYJ B;  4MMY B;  3FCS B;  1HT5 A;  2UWO B;  2BO2 A;  3TBD A;  1K37 A;  4XL1 A;  2WPK E;  1ATD A;  4BDX A;  1FAX L;  1KLI L;  5FDQ A;  3KQD L;  1TPG A;  4CUD A;  1OB1 C;  2J2U B;  1LPZ A;  2NPR A;  4M11 A;  4BTT A;  5CKM A;  5JB8 E;  4ISI L;  4ZXY L;  2FLB L;  1CX2 A;  2J94 B;  5CIS A;  1IQH L;  1EQH A;  1APO A;  1UZK A;  1J9C L;  4PH9 A;  2M74 A;  4A7I A;  3IJE B;  3TK5 B;  1EPG A;  2J4I B;  2YGO A;  2Y5G L;  4JZF L;  2XC0 L;  2K2S B;  1M1X B;  2W2O E;  3N8Z A;  3F6U L;  3GCX E;  1EBV A;  2I9A A;  1IP0 A;  2DDU A;  4OTY A;  2AYL A;  5KN5 C;  1MQ5 L;  3V64 C;  4X8S L;  1IQI L;  1L3Y A;  2TGF A;  3C9A C;  1IQN L;  5JBA E;  2EI7 B;  1WU1 B;  2W2M E;  2XBX L;  5IKR A;  2RNL A;  3KQC L;  3LN1 A;  2W2Q E;  1TOZ A;  1NFY B;  2PR3 B;  1X7A L;  2VVC K;  3LTG D;  4ZAE B;  3CFW A;  1TLE A;  5KIR A;  2Y80 B;  3MDL A;  4D0F A;  1GK5 A;  2Y5H L;  3HS7 A;  2XC5 L;  1KLJ L;  3U7U G;  4Y79 B;  1ATA A;  1EPI A;  2VWL L;  1G1Q A;  1FJS L;  1UZJ A;  4YT6 L;  2GD4 A;  3U73 A;  2JKH L;  1DIY A;  3LAQ A;  4NGA L;  1I0U A;  4RRZ A;  5F1A A;  1PFX L;  3QCW A;  4BDW A;  1FFM A;  1Z6E L;  2OYU P;  3CA7 A;  2FZZ L;  2ADX A;  1ATE A;  4Y76 B;  2P93 L;  2Y7X B;  3EGF A;  6COX A;  2VVV L;  1CVW L;  2W26 B;  3OLU A;  3M36 L;  1N1I A;  2WFX B;  1IQJ L;  1QFK L;  4BTU A;  3SOQ A;  3LIW B;  3N8W B;  2RA0 L;  3NTB A;  1CQE A;  5L2Z L;  2WG4 B;  1G2M B;  5JBB E;  3IIT B;  2FD6 A;  1V3X B;  1KSN B;  1NQL B;  2EI6 B;  4Z6A L;  2W2P E;  1IOX A;  1EMO A;  3FBY A;  3NTG A;  3OLT A;  4E1G A;  3N8Y B;  5JVZ A;  1ATB A;  2P16 L;  1NPE B;  1DDX A;  1YUG A;  4RUT A;  4XLW A;  5JW1 A;  1YO8 A;  2F9B L;  5E8D A;  4O1Z A;  2BZ6 L;  1EZQ B;  3K9X A;  3H5C B;  1LPG A;  2VWO L;  4ZHA B;  1XDT R;  1O5D L;  2WYJ B;  1ADX A;  1IQG L;  5I46 L;  1K36 A;  1XKB A;  2UWL B;  2W86 A;  1FE2 A;  2W3K B;  1W8B L;  3R05 A;  4RRY A;  1G1S A;  3PGH A;  4COX A;  1HRF A;  2VH0 B;  3LC3 B;  1Z6C A;  3NJP C;  3CEN L;  1IVO C;  3Q7D A;  1LQD A;  4TGF A;  3LC5 B;  1DQB A;  1G1R A;  4ZXX L;  2XBW L;  1DVA L;  1F0S B;  1URK A;  1P9J A;  5COX A;  3SW2 A;  2BQ7 A;  5CKQ A;  3GCW E;  4LMF A;  3SOB B;  1EAI C;  2B7D L;  4Z0L A;  1LPK A;  4BTI A;  3P5B L;  3GIS X;  1IQF L;  1EMN A;  3TK6 B;  1IQM L;  3ENS A;  4MMZ B;  2BOK L;  2G00 L;  1IQE L;  4YT7 L;  1ZAQ A;  2BOH A;  3HO5 A;  2FLG A;  2Y7Z B;  4JYV L;  1IGX A;  2H9E L;  3HS6 A;  1APQ A;  4ISH L;  4BXS A;  1CCV A;  4ZH8 B;  2XC4 L;  1HAE A;  1MOX C;  2P3F N;  3LN0 A;  1G2L B;  2OYE P;  3M37 L;  1HX2 A;  2P3F L;  1LMJ A;  1CCF A;  2P28 B;  2D1J B;  4OTJ A;  4CSY A;  4FM5 A;  3NT1 A;  1UZQ A;  1NFX B;  2J95 B;  2J38 B;  1W7X L;  5JVY A;  1FAK L;  3RR3 A;  1COU A;  1KIG L;  2VH6 B;  3MQE A;  4O02 B;  3KCG L;  1HZ8 A;  1F0R B;  2VWM K;  3KRK A;  4Y7A B;  4D90 A;  4XBM A;  2EI8 B;  4Z0K B;  1SZB A;  3BPS E;  4MMX B;  2P3U A;  2XBY L;  2VVU L;  3Q3K B;  1CVU A;  2FLR L;  1C5M F;  1PGE A;  4YZU B;  1HRE A;  1F7M A;  1IGZ A;  1PTH A; 
#chains in the Genus database with same CATH topology
 2WYG B;  3ZYI B;  1JV2 B;  1NFU B;  2MHP A;  2VJ3 A;  4NA9 L;  4X8T L;  5JBC E;  1JL9 A;  2WPL E;  4CUE A;  1EGF A;  1IQK L;  1KLO A;  1U67 A;  4D0E A;  2WFT A;  3POY A;  4NG9 L;  1HAF A;  3SOV A;  2W2N E;  4Y71 B;  3ZYG A;  3F1S B;  2KL7 A;  3N8Y A;  2YGQ A;  2BT8 A;  1WHE A;  4GU4 A;  3HO3 A;  1HCG B;  3BT2 A;  2HOR A;  2WPH E;  2I9B A;  1NFW B;  1YUK B;  2BOX A;  2PUQ L;  2MGP A;  2P26 A;  4G1M B;  1XKA L;  3ELA L;  3V65 B;  2RHP A;  4JZE L;  2VWN L;  1EQG A;  5K0H B;  3N8V A;  3CS7 L;  1FSB A;  2KV4 A;  1MQ6 L;  1NT0 A;  3QH0 A;  4Y7B B;  2BQ6 A;  1BF9 A;  2KB9 A;  1A3P A;  5F19 A;  5CKN A;  1DX5 I;  1XFE A;  2YGP A;  3KQE L;  3LTF B;  3KQB L;  1IQL L;  1AUT L;  3HO4 A;  2P3T A;  2J34 B;  1F7E A;  1G1T A;  1N7D A;  1UZP A;  3ASI A;  2PHB B;  4JYU L;  5IKV A;  2UWP B;  2P95 L;  1P0S L;  3HPT A;  4AQT A;  1EPH A;  4X8V L;  1JBU L;  3QMO A;  1YUF A;  2Q1J B;  1RFN B;  1FF7 A;  4JZD L;  4LOR A;  2Y82 B;  4M10 A;  1YGC L;  1CEJ A;  2WPM E;  2P94 L;  4BXW A;  2WG3 C;  2Y81 B;  2Y5F L;  3KK6 A;  1L5G B;  3TZI A;  5IKQ A;  3KL6 B;  4RS0 A;  5L30 L;  2H9E C;  1HJ7 A;  2BQW A;  3HS5 A;  2K2T A;  5IKT A;  4RRW A;  1B9W A;  2BMG A;  3FFG L;  2BOU A;  1Q4G A;  4C16 A;  3BT1 A;  1LMM A;  4X8U L;  2MGR A;  4Y6D B;  2HOX A;  2WPI E;  3N8X A;  3DEM A;  4A94 C;  5EGM B;  1IOE L;  1NZI A;  2Y38 A;  3TGF A;  2WPJ E;  3TH3 L;  2XBV L;  4CUF A;  1U8C B;  5L2Y L;  5JB9 E;  1HT8 A;  2CJI B;  3N8W A;  1WHF A;  1PRH A;  2W3I B;  4RRX A;  1IJQ A;  1PXX A;  1EPJ A;  3ZYJ B;  4MMY B;  3FCS B;  1HT5 A;  2UWO B;  2BO2 A;  3TBD A;  1K37 A;  4XL1 A;  2WPK E;  1ATD A;  4BDX A;  1FAX L;  1KLI L;  5FDQ A;  3KQD L;  1TPG A;  4CUD A;  1OB1 C;  2J2U B;  1LPZ A;  2NPR A;  4M11 A;  4BTT A;  5CKM A;  5JB8 E;  4ISI L;  4ZXY L;  2FLB L;  1CX2 A;  2J94 B;  5CIS A;  1IQH L;  1EQH A;  1APO A;  1UZK A;  1J9C L;  4PH9 A;  2M74 A;  4A7I A;  3IJE B;  3TK5 B;  1EPG A;  2J4I B;  2YGO A;  2Y5G L;  4JZF L;  2XC0 L;  2K2S B;  1M1X B;  2W2O E;  3N8Z A;  3F6U L;  3GCX E;  1EBV A;  2I9A A;  1IP0 A;  2DDU A;  4OTY A;  2AYL A;  5KN5 C;  1MQ5 L;  3V64 C;  4X8S L;  1IQI L;  1L3Y A;  2TGF A;  3C9A C;  1IQN L;  5JBA E;  2EI7 B;  1WU1 B;  2KNI A;  2W2M E;  2XBX L;  5IKR A;  2RNL A;  3KQC L;  3LN1 A;  2W2Q E;  1TOZ A;  1NFY B;  2PR3 B;  1X7A L;  2VVC K;  3LTG D;  4ZAE B;  3CFW A;  1TLE A;  5KIR A;  2Y80 B;  3MDL A;  4D0F A;  1GK5 A;  2Y5H L;  3HS7 A;  2XC5 L;  2VRS A;  1KLJ L;  3U7U G;  4Y79 B;  1ATA A;  1EPI A;  2VWL L;  1G1Q A;  1FJS L;  1UZJ A;  4YT6 L;  2GD4 A;  3U73 A;  2JKH L;  1V1H A;  1DIY A;  3LAQ A;  4NGA L;  1I0U A;  4RRZ A;  5F1A A;  1PFX L;  3QCW A;  4BDW A;  1FFM A;  1Z6E L;  2OYU P;  3CA7 A;  2FZZ L;  2ADX A;  1ATE A;  4Y76 B;  2P93 L;  2Y7X B;  1QIU A;  3EGF A;  6COX A;  2VVV L;  1CVW L;  2W26 B;  3OLU A;  3M36 L;  1N1I A;  2WFX B;  1IQJ L;  1QFK L;  4BTU A;  3SOQ A;  3LIW B;  3N8W B;  2RA0 L;  3NTB A;  1CQE A;  5L2Z L;  2WG4 B;  1G2M B;  5JBB E;  3IIT B;  2FD6 A;  1V3X B;  1KSN B;  1NQL B;  2EI6 B;  4Z6A L;  2W2P E;  1IOX A;  1EMO A;  3FBY A;  3NTG A;  3OLT A;  4E1G A;  3N8Y B;  5JVZ A;  1ATB A;  2P16 L;  1NPE B;  2BT7 A;  1DDX A;  1YUG A;  4RUT A;  4XLW A;  5JW1 A;  1YO8 A;  2F9B L;  5E8D A;  4O1Z A;  2BZ6 L;  1EZQ B;  3K9X A;  3H5C B;  1LPG A;  2VWO L;  4ZHA B;  1XDT R;  1O5D L;  2WYJ B;  1ADX A;  1IQG L;  5I46 L;  1K36 A;  1XKB A;  2UWL B;  2W86 A;  2JJL A;  1FE2 A;  2W3K B;  1W8B L;  3R05 A;  4RRY A;  1G1S A;  3PGH A;  4COX A;  1HRF A;  2VH0 B;  3LC3 B;  1Z6C A;  3NJP C;  3CEN L;  1IVO C;  3Q7D A;  1LQD A;  4TGF A;  3LC5 B;  1DQB A;  1G1R A;  4ZXX L;  1LK9 A;  2XBW L;  1DVA L;  1F0S B;  1URK A;  1P9J A;  5COX A;  3SW2 A;  2BQ7 A;  5CKQ A;  3GCW E;  4LMF A;  3SOB B;  1EAI C;  2B7D L;  4Z0L A;  1LPK A;  4BTI A;  3P5B L;  3GIS X;  1IQF L;  2WZP P;  1EMN A;  3TK6 B;  1KKE A;  1IQM L;  3ENS A;  4MMZ B;  2BOK L;  2G00 L;  1IQE L;  4YT7 L;  1ZAQ A;  2BOH A;  3HO5 A;  2FLG A;  2Y7Z B;  4JYV L;  1IGX A;  2H9E L;  3HS6 A;  1APQ A;  4ISH L;  4BXS A;  1CCV A;  4ZH8 B;  2XC4 L;  1HAE A;  1MOX C;  2P3F N;  3LN0 A;  1G2L B;  2OYE P;  3M37 L;  1HX2 A;  2P3F L;  1LMJ A;  1CCF A;  2P28 B;  2D1J B;  1V1I A;  4OTJ A;  4CSY A;  4FM5 A;  3NT1 A;  1UZQ A;  1NFX B;  2J95 B;  2J38 B;  1W7X L;  5JVY A;  1FAK L;  3RR3 A;  1COU A;  1KIG L;  2VH6 B;  3MQE A;  4O02 B;  3KCG L;  1HZ8 A;  1F0R B;  2VWM K;  4GU3 A;  3KRK A;  4Y7A B;  4D90 A;  4XBM A;  2EI8 B;  4Z0K B;  1SZB A;  3BPS E;  4MMX B;  2P3U A;  2XBY L;  2BSF A;  2VVU L;  3Q3K B;  3S6X A;  1CVU A;  2FLR L;  1C5M F;  1PGE A;  4YZU B;  1HRE A;  1F7M A;  1IGZ A;  1PTH A; 
#chains in the Genus database with same CATH homology
 2WYG B;  3ZYI B;  1JV2 B;  1NFU B;  2MHP A;  2VJ3 A;  4NA9 L;  4X8T L;  5JBC E;  1JL9 A;  2WPL E;  4CUE A;  1EGF A;  1IQK L;  1KLO A;  1U67 A;  4D0E A;  2WFT A;  3POY A;  4NG9 L;  1HAF A;  3SOV A;  2W2N E;  4Y71 B;  3ZYG A;  3F1S B;  2KL7 A;  3N8Y A;  2YGQ A;  1WHE A;  3HO3 A;  1HCG B;  3BT2 A;  2WPH E;  2I9B A;  1NFW B;  1YUK B;  2BOX A;  2PUQ L;  2MGP A;  2P26 A;  4G1M B;  1XKA L;  3ELA L;  3V65 B;  2RHP A;  4JZE L;  2VWN L;  1EQG A;  5K0H B;  3N8V A;  3CS7 L;  1FSB A;  2KV4 A;  1MQ6 L;  1NT0 A;  3QH0 A;  4Y7B B;  2BQ6 A;  1BF9 A;  2KB9 A;  1A3P A;  5F19 A;  5CKN A;  1DX5 I;  1XFE A;  2YGP A;  3KQE L;  3LTF B;  3KQB L;  1IQL L;  1AUT L;  3HO4 A;  2P3T A;  2J34 B;  1F7E A;  1G1T A;  1N7D A;  1UZP A;  3ASI A;  2PHB B;  4JYU L;  5IKV A;  2UWP B;  2P95 L;  1P0S L;  3HPT A;  4AQT A;  1EPH A;  4X8V L;  1JBU L;  3QMO A;  1YUF A;  2Q1J B;  1RFN B;  1FF7 A;  4JZD L;  4LOR A;  2Y82 B;  4M10 A;  1YGC L;  1CEJ A;  2WPM E;  2P94 L;  4BXW A;  2WG3 C;  2Y81 B;  2Y5F L;  3KK6 A;  1L5G B;  3TZI A;  5IKQ A;  3KL6 B;  4RS0 A;  5L30 L;  2H9E C;  1HJ7 A;  2BQW A;  3HS5 A;  2K2T A;  5IKT A;  4RRW A;  1B9W A;  2BMG A;  3FFG L;  2BOU A;  1Q4G A;  4C16 A;  3BT1 A;  1LMM A;  4X8U L;  2MGR A;  4Y6D B;  2WPI E;  3N8X A;  3DEM A;  4A94 C;  5EGM B;  1IOE L;  1NZI A;  2Y38 A;  3TGF A;  2WPJ E;  3TH3 L;  2XBV L;  4CUF A;  1U8C B;  5L2Y L;  5JB9 E;  1HT8 A;  2CJI B;  3N8W A;  1WHF A;  1PRH A;  2W3I B;  4RRX A;  1IJQ A;  1PXX A;  1EPJ A;  3ZYJ B;  4MMY B;  3FCS B;  1HT5 A;  2UWO B;  2BO2 A;  3TBD A;  1K37 A;  4XL1 A;  2WPK E;  1ATD A;  4BDX A;  1FAX L;  1KLI L;  5FDQ A;  3KQD L;  1TPG A;  4CUD A;  1OB1 C;  2J2U B;  1LPZ A;  2NPR A;  4M11 A;  4BTT A;  5CKM A;  5JB8 E;  4ISI L;  4ZXY L;  2FLB L;  1CX2 A;  2J94 B;  5CIS A;  1IQH L;  1EQH A;  1APO A;  1UZK A;  1J9C L;  4PH9 A;  2M74 A;  4A7I A;  3IJE B;  3TK5 B;  1EPG A;  2J4I B;  2YGO A;  2Y5G L;  4JZF L;  2XC0 L;  2K2S B;  1M1X B;  2W2O E;  3N8Z A;  3F6U L;  3GCX E;  1EBV A;  2I9A A;  1IP0 A;  2DDU A;  4OTY A;  2AYL A;  5KN5 C;  1MQ5 L;  3V64 C;  4X8S L;  1IQI L;  1L3Y A;  2TGF A;  3C9A C;  1IQN L;  5JBA E;  2EI7 B;  1WU1 B;  2KNI A;  2W2M E;  2XBX L;  5IKR A;  2RNL A;  3KQC L;  3LN1 A;  2W2Q E;  1TOZ A;  1NFY B;  2PR3 B;  1X7A L;  2VVC K;  3LTG D;  4ZAE B;  3CFW A;  1TLE A;  5KIR A;  2Y80 B;  3MDL A;  4D0F A;  1GK5 A;  2Y5H L;  3HS7 A;  2XC5 L;  1KLJ L;  3U7U G;  4Y79 B;  1ATA A;  1EPI A;  2VWL L;  1G1Q A;  1FJS L;  1UZJ A;  4YT6 L;  2GD4 A;  3U73 A;  2JKH L;  1DIY A;  3LAQ A;  4NGA L;  1I0U A;  4RRZ A;  5F1A A;  1PFX L;  3QCW A;  4BDW A;  1FFM A;  1Z6E L;  2OYU P;  3CA7 A;  2FZZ L;  2ADX A;  1ATE A;  4Y76 B;  2P93 L;  2Y7X B;  3EGF A;  6COX A;  2VVV L;  1CVW L;  2W26 B;  3OLU A;  3M36 L;  1N1I A;  2WFX B;  1IQJ L;  1QFK L;  4BTU A;  3SOQ A;  3LIW B;  3N8W B;  2RA0 L;  3NTB A;  1CQE A;  5L2Z L;  2WG4 B;  1G2M B;  5JBB E;  3IIT B;  2FD6 A;  1V3X B;  1KSN B;  1NQL B;  2EI6 B;  4Z6A L;  2W2P E;  1IOX A;  1EMO A;  3FBY A;  3NTG A;  3OLT A;  4E1G A;  3N8Y B;  5JVZ A;  1ATB A;  2P16 L;  1NPE B;  1DDX A;  1YUG A;  4RUT A;  4XLW A;  5JW1 A;  1YO8 A;  2F9B L;  5E8D A;  4O1Z A;  2BZ6 L;  1EZQ B;  3K9X A;  3H5C B;  1LPG A;  2VWO L;  4ZHA B;  1XDT R;  1O5D L;  2WYJ B;  1ADX A;  1IQG L;  5I46 L;  1K36 A;  1XKB A;  2UWL B;  2W86 A;  1FE2 A;  2W3K B;  1W8B L;  3R05 A;  4RRY A;  1G1S A;  3PGH A;  4COX A;  1HRF A;  2VH0 B;  3LC3 B;  1Z6C A;  3NJP C;  3CEN L;  1IVO C;  3Q7D A;  1LQD A;  4TGF A;  3LC5 B;  1DQB A;  1G1R A;  4ZXX L;  2XBW L;  1DVA L;  1F0S B;  1URK A;  1P9J A;  5COX A;  3SW2 A;  2BQ7 A;  5CKQ A;  3GCW E;  4LMF A;  3SOB B;  1EAI C;  2B7D L;  4Z0L A;  1LPK A;  4BTI A;  3P5B L;  3GIS X;  1IQF L;  2WZP P;  1EMN A;  3TK6 B;  1IQM L;  3ENS A;  4MMZ B;  2BOK L;  2G00 L;  1IQE L;  4YT7 L;  1ZAQ A;  2BOH A;  3HO5 A;  2FLG A;  2Y7Z B;  4JYV L;  1IGX A;  2H9E L;  3HS6 A;  1APQ A;  4ISH L;  4BXS A;  1CCV A;  4ZH8 B;  2XC4 L;  1HAE A;  1MOX C;  2P3F N;  3LN0 A;  1G2L B;  2OYE P;  3M37 L;  1HX2 A;  2P3F L;  1LMJ A;  1CCF A;  2P28 B;  2D1J B;  4OTJ A;  4CSY A;  4FM5 A;  3NT1 A;  1UZQ A;  1NFX B;  2J95 B;  2J38 B;  1W7X L;  5JVY A;  1FAK L;  3RR3 A;  1COU A;  1KIG L;  2VH6 B;  3MQE A;  4O02 B;  3KCG L;  1HZ8 A;  1F0R B;  2VWM K;  3KRK A;  4Y7A B;  4D90 A;  4XBM A;  2EI8 B;  4Z0K B;  1SZB A;  3BPS E;  4MMX B;  2P3U A;  2XBY L;  2VVU L;  3Q3K B;  3S6X A;  1CVU A;  2FLR L;  1C5M F;  1PGE A;  4YZU B;  1HRE A;  1F7M A;  1IGZ A;  1PTH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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