2G6ZA

Crystal structure of human dusp5
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
147
structure length
147
Chain Sequence
GSHMGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACMTHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHSEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the catalytic domain of human DUSP5, a dual specificity MAP kinase protein phosphatase
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Dual specificity protein phosphatase 5
total genus 51
structure length 147
sequence length 147
chains with identical sequence B, C
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2006-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00782 DSPc Dual specificity phosphatase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2g6zA00
2J16A 4H1OA 3O3LA 1YWFA 5IBSA 4DGPA 3CWEA 5BZZA 1U25A 3QKQA 2RF6A 3V0HA 2H03A 4NNDA 4ERCA 1WRMA 4RDDA 1BZCA 3QCJA 3QCFA 2PT0A 1I9TA 2YDUA 2NZ6A 2I75A 3H2XA 2I4EA 4YAAA 4Z6BA 1LQFA 1T4JA 2QBRA 3A5JA 2BZLA 2J16B 2I6JA 1OHEA 5KACA 2G6ZA 2ESBA 2FJNA 1U24A 2GWOA 3MOZA 2F46A 3BRHA 1ZCKA 4RH9A 4NWGA 3F81A 4KYRA 2Y2FA 3V0DA 2I6OA 2F6ZA 2H04A 2VEVA 2CMBA 4GFVA 2BIJA 2CM3A 3QCCA 4QAHA 1PTVA 4WU2A 4WTYA 5EHPA 3A5KA 2BV5A 1U26A 2H4GA 2CNIA 1XBOA 1OHDA 4RHGA 2NTAA 2HXPA 1X24A 3QCMA 3QKPA 3LJ8A 4ZRTA 2B4UA 1BZHA 3EAXA 1XM2A 3ZM3A 1D5RA 2F6VA 5BZXA 1G7FA 5J8RA 3F99A 3BLTA 3V0EA 4AZ1A 2ZMMA 3QCIA 1QXKA 4KYQA 3ZM2A 1OEOX 1P15A 2I5XA 2BGDA 4S0GA 2QBQA 3OMHA 1M3GA 1QZ0A 4OHDA 4PYHA 4H34A 3F9AA 4RH5A 1C85A 1WCHA 2B4SA 1OHCA 2CMAA 2M3VA 2Y96A 4RI5A 1ONYA 1Q6MA 3ZM1A 3QCGA 3GXHA 2HY3A 1YGRA 1WAXA 2B49A 2VEYA 1PTUA 2QDPA 4KI9A 4RKKA 4J51A 4GWFA 3F41A 4D3PA 2VEXA 1NWEA 3D44A 1A5YA 4GS0A 1NO6A 2QCTA 2Q47A 5KA3A 3NMEA 2PI7A 3O5XA 2BGEA 2CNGA 2C7SA 3V0GA 3M4UA 1L8GA 2HNPA 5K22A 3BM8A 3AWGA 3SMEA 1Q1MA 2CM7A 1C87A 1AAXA 2HNQA 2HB1A 2A8BA 2OC3A 1YTWA 2GJTA 3EU0A 1ONZA 4NWFA 1C84A 4HRFA 4GE6A 1BZJA 5IBMA 1NL9A 1G1FA 2SHPA 2I6IA 5AWXA 1ECVA 3D1QA 4NX8A 4R30A 4MBBA 2QCJA 1ZC0A 2B4PA 2GP0A 2HVLA 2CNHA 2B07A 5BX1A 1XXVA 4ZN5A 3I7ZA 2F6WA 3MOWA 3QCKA 1XRIA 3S3KA 4QBEA 2I1YA 2FH7A 4QAPA 2B3OA 3S3EA 1EENA 1G7GA 1Q6PA 4GFUA 5KA1A 3PS5A 2NV5A 5EHRA 1GFYA 3QCHA 1JLNA 1G4US 2PA5A 2Q05A 1NNYA 4RI4A 3S3HA 4HJQA 1NZ7A 2H4VA 1GWZA 5I6VA 2I4HA 1Q6SA 2MBCA 3N0AA 3RO1A 5K24A 1J4XA 1EEOA 4WOHA 4GRZA 3EB1A 5GTJA 2A3KA 2I3UA 2F6TA 1ZZWA 5M43A 3SR9A 5KA2A 2PQ5A 2FJMA 1YPTA 1ZCLA 2WGPA 1I9SA 1PXHA 2H4KA 1PH0A 1G1HA 1XXPA 3I80A 1OEVA 2F6YA 1G1GA 3QCDA 5KA9A 5K25A 4QUNA 2PBNA 2QBPA 3RGOA 4JNBA 4WU3A 3D42A 3B7OA 1YTNA 3MMJA 1SUGA 2F6FA 2F70A 2DXPA 3O4TA 2NLKA 3CM3A 3V0JA 1FPRA 2VEWA 1G4WR 2I6MA 3BLUA 3V0IA 2HC1A 3RZ2A 2OUDA 2PSZA 3D1HA 3F9BA 4YR8B 3S3FA 5KA4A 3S4OA 3QCEA 3U96A 3ZMPA 1YFOA 1JF7A 5BUGA 5LXQB 3OLRA 5KAAA 3RGQA 3QCBA 2CFVA 2NT2A 2IMGA 2P4DA 1RPMA 2CM8A 4JMJA 4GE5A 4GE2A 1YZ4A 4D3RA 2VEUA 1PTYA 5MMZB 3ZV2A 4ZI4A 1LARA 1V3AA 1PA9A 4B04A 2F71A 4QBWA 3EMUA 1Q6NA 3O4UA 2HCMA 1OESA 2G59A 5KA0A 1NWLA 2I42A 5K23A 2QEPA 4IKCA 4GRYA 2HC2A 4R0TA 1YGUA 1T49A 2C46A 1C86A 3GXGA 4HJPA 1Q6TA 5KA8A 1R6HA 2CMCA 1PA1A 2OZ5A 2I4GA 1YTSA 1FQ1A 4I8NA 1FPZA 4D3QA 3QCNA 4JBCA 2I3RA 3AWFA 4TVVA 1KAVA 2R0BA 2JJDA 3D9CA 4NYHA 5K9VA 2QBSA 3ZM0A 1T48A 2J17A 3D1OA 4BPCA 1Q6JA 1LYVA 2NT7A 4OHIA 4JMKA 4ICZA 4R0SA 1C83A 1MKPA 3S4EA 2ZN7A 5KABA 1C88A 1KAKA 3QCLA 4OHLA 4Y14A 2E0TA 2AHSA 2I6PA 3AWEA 5K9WA 1L8KA 1OEUA 2OOQA 3ZMQA 4PVGA 4OHHA 2CNFA 2QDMA 2CM2A 4BJOA 3EZZA 1PYNA 4OHEA 2CJZA 4QUMA 1OEMX 2QDCA 3I36A 4DGXA 4Y2EA 1VHRA 2AZRA 2CNEA 1YN9A 5HDEA 1RXDA 2P6XA 2H02A 5KA7A 1PTTA 3O4SA 5KADA 2B4OA 1I57A 1OETA 3V0FA
chains in the Genus database with same CATH superfamily
2J16A 4H1OA 3O3LA 1YWFA 5IBSA 4DGPA 3CWEA 5BZZA 1U25A 3QKQA 2RF6A 3V0HA 2H03A 4NNDA 4ERCA 1WRMA 4RDDA 1BZCA 3QCJA 3QCFA 2PT0A 1I9TA 2YDUA 2NZ6A 2I75A 4UAGA 3H2XA 2I4EA 4YAAA 4Z6BA 1LQFA 1T4JA 2QBRA 3ZL8A 3A5JA 2BZLA 2J16B 2I6JA 1OHEA 5KACA 2G6ZA 2ESBA 2FJNA 1U24A 2GWOA 3MOZA 2F46A 3BRHA 3QCZA 1ZCKA 4RH9A 4NWGA 3F81A 4KYRA 2Y2FA 3V0DA 2I6OA 2F6ZA 2H04A 2VEVA 2CMBA 4GFVA 4CVKA 2BIJA 2CM3A 2UUOA 3QCCA 4QAHA 1PTVA 4WU2A 3PYZA 4WTYA 5EHPA 3A5KA 2BV5A 1U26A 2H4GA 2CNIA 1XBOA 1OHDA 4RHGA 2NTAA 2JFGA 2HXPA 1X24A 3QCMA 3QKPA 3LJ8A 4ZRTA 2B4UA 1BZHA 3EAXA 1XM2A 2GC5A 3ZM3A 1D5RA 2F6VA 5BZXA 1G7FA 5J8RA 3F99A 3BLTA 3V0EA 2UAGA 4AZ1A 2ZMMA 3QCIA 1QXKA 4KYQA 3ZM2A 1OEOX 1P15A 2I5XA 2GC6A 2BGDA 4S0GA 2QBQA 3OMHA 1M3GA 1QZ0A 3UAGA 4OHDA 4PYHA 4H34A 3F9AA 4RH5A 3ZM6A 1C85A 1WCHA 2B4SA 1OHCA 2CMAA 2M3VA 2Y96A 4RI5A 3ZM5A 1ONYA 1Q6MA 3ZM1A 2Y1OA 3QCGA 5A5FA 3GXHA 2HY3A 1YGRA 5A5EA 1WAXA 2B49A 2VEYA 1PTUA 2XJAA 2QDPA 2JFHA 4KI9A 4QDIA 4RKKA 4J51A 4GWFA 3F41A 1FGSA 4D3PA 2VEXA 1NWEA 3D44A 1A5YA 4GS0A 4C13A 1NO6A 2QCTA 2Q47A 5KA3A 3NMEA 2PI7A 3O5XA 2BGEA 2CNGA 2C7SA 3V0GA 3MVNA 3M4UA 1L8GA 2HNPA 5K22A 3BM8A 3AWGA 3SMEA 1Q1MA 2CM7A 1C87A 1AAXA 2HNQA 2F00A 2HB1A 2A8BA 2GCAA 2OC3A 1YTWA 2GJTA 3EU0A 1ONZA 4NWFA 1C84A 4HRFA 4GE6A 1BZJA 5IBMA 2VOSA 1NL9A 1G1FA 2SHPA 2I6IA 5AWXA 1ECVA 3D1QA 4NX8A 4R30A 4MBBA 2QCJA 1ZC0A 2B4PA 2GP0A 2HVLA 2CNHA 2B07A 5BX1A 1XXVA 4ZN5A 3I7ZA 2F6WA 3MOWA 3QCKA 1XRIA 3S3KA 4QBEA 2I1YA 2FH7A 4QAPA 2B3OA 3S3EA 1GQYA 1EENA 1G7GA 1Q6PA 4GFUA 5KA1A 3PS5A 2NV5A 5EHRA 1GFYA 3QCHA 1JLNA 1G4US 2PA5A 2XPCA 4QF5A 2Q05A 1NNYA 4RI4A 3S3HA 4BUBA 4HJQA 1NZ7A 2H4VA 1GWZA 5I6VA 2I4HA 1Q6SA 4BUCA 2MBCA 3N0AA 3RO1A 5K24A 1J4XA 1EEOA 2Y66A 4WOHA 1EEHA 4GRZA 3EB1A 5GTJA 2A3KA 2I3UA 2F6TA 1ZZWA 5M43A 3SR9A 5KA2A 2GCBA 2PQ5A 2FJMA 1YPTA 1ZCLA 2WGPA 1I9SA 1PXHA 2AM2A 2H4KA 1O5ZA 1PH0A 1G1HA 1XXPA 2VORA 3I80A 4ZIYA 1OEVA 1JBWA 2F6YA 1G1GA 3QCDA 5KA9A 5K25A 4QUNA 2WTZA 3HN7A 2PBNA 1W7KA 2WJPA 2QBPA 3RGOA 4JNBA 4WU3A 3D42A 3B7OA 2UUPA 1YTNA 3MMJA 1SUGA 2F6FA 2F70A 2DXPA 1GG4A 3O4TA 2NLKA 3CM3A 3V0JA 1FPRA 2VEWA 1G4WR 1P3DA 2I6MA 3BLUA 3V0IA 2HC1A 3RZ2A 2OUDA 2PSZA 2AM1A 3D1HA 3F9BA 4YR8B 3S3FA 5KA4A 3S4OA 3QCEA 3U96A 3ZMPA 1YFOA 1JF7A 5BUGA 5LXQB 3OLRA 5KAAA 3RGQA 3QCBA 2CFVA 2NT2A 2IMGA 2P4DA 1RPMA 2CM8A 4JMJA 4GE5A 4GE2A 1YZ4A 4D3RA 1PTYA 2VEUA 1JBVA 5MMZB 3ZV2A 4ZI4A 1LARA 1V3AA 1PA9A 4B04A 2F71A 4QBWA 3EMUA 1Q6NA 3O4UA 2HCMA 1OESA 2G59A 5KA0A 1NWLA 2I42A 1J6UA 5K23A 2QEPA 4IKCA 4GRYA 2HC2A 1GQQA 4R0TA 1UAGA 1YGUA 1T49A 2C46A 1C86A 3GXGA 4HJPA 1Q6TA 1E8CA 5KA8A 1R6HA 2CMCA 1PA1A 2OZ5A 2I4GA 1YTSA 2VTEA 1FQ1A 4I8NA 1FPZA 4D3QA 3QCNA 4JBCA 2I3RA 3AWFA 4TVVA 1KAVA 2R0BA 2JJDA 1W78A 2Y67A 3D9CA 4NYHA 5K9VA 2QBSA 3ZM0A 4C12A 1T48A 2J17A 3D1OA 4BPCA 1Q6JA 1LYVA 2X5OA 2Y68A 2NT7A 4OHIA 4JMKA 4ICZA 4R0SA 1C83A 1MKPA 3S4EA 2ZN7A 5KABA 1C88A 1KAKA 3QCLA 4OHLA 4Y14A 2E0TA 2AHSA 2I6PA 3AWEA 5K9WA 1L8KA 1OEUA 2OOQA 3ZMQA 4PVGA 4OHHA 2CNFA 2QDMA 2CM2A 4BJOA 2JFFA 3EZZA 3N2AA 1PYNA 4OHEA 2CJZA 4QUMA 2VTDA 1OEMX 2QDCA 3I36A 4DGXA 3LK7A 4Y2EA 1P31A 1VHRA 2AZRA 2CNEA 1YN9A 5HDEA 1RXDA 2P6XA 3NRSA 2H02A 1E0DA 5KA7A 1PTTA 3O4SA 4HV4A 5KADA 4CVMA 2B4OA 4CVLA 1I57A 1OETA 3V0FA
chains in the Genus database with same CATH topology
2J16A 4H1OA 3O3LA 1YWFA 5IBSA 4DGPA 3CWEA 5BZZA 1U25A 3QKQA 2RF6A 3V0HA 2H03A 4NNDA 4ERCA 1WRMA 4RDDA 1BZCA 3QCJA 3QCFA 2PT0A 1I9TA 2YDUA 2NZ6A 2I75A 3H2XA 2I4EA 4YAAA 4Z6BA 1LQFA 1T4JA 2QBRA 3A5JA 2BZLA 2J16B 2I6JA 1OHEA 5KACA 2G6ZA 2ESBA 2FJNA 1U24A 2GWOA 3MOZA 2F46A 3BRHA 1ZCKA 4RH9A 4NWGA 3F81A 4KYRA 2Y2FA 3V0DA 2I6OA 2F6ZA 2H04A 2VEVA 2CMBA 4GFVA 2BIJA 2CM3A 3QCCA 4QAHA 1PTVA 4WU2A 4WTYA 5EHPA 3A5KA 2BV5A 1U26A 2H4GA 2CNIA 1XBOA 1OHDA 4RHGA 2NTAA 2HXPA 1X24A 3QCMA 3QKPA 3LJ8A 4ZRTA 2B4UA 1BZHA 3EAXA 1XM2A 3ZM3A 1D5RA 2F6VA 5BZXA 1G7FA 5J8RA 3F99A 3BLTA 3V0EA 4AZ1A 2ZMMA 3QCIA 1QXKA 4KYQA 3ZM2A 1OEOX 1P15A 2I5XA 2BGDA 4S0GA 2QBQA 3OMHA 1M3GA 1QZ0A 4OHDA 4PYHA 4H34A 3F9AA 4RH5A 1C85A 1WCHA 2B4SA 1OHCA 2CMAA 2M3VA 2Y96A 4RI5A 1ONYA 1Q6MA 3ZM1A 3QCGA 3GXHA 2HY3A 1YGRA 1WAXA 2B49A 2VEYA 1PTUA 2QDPA 4KI9A 4RKKA 4J51A 4GWFA 3F41A 4D3PA 2VEXA 1NWEA 3D44A 1A5YA 4GS0A 1NO6A 2QCTA 2Q47A 5KA3A 3NMEA 2PI7A 3O5XA 2BGEA 2CNGA 2C7SA 3V0GA 3M4UA 1L8GA 2HNPA 5K22A 3BM8A 3AWGA 3SMEA 1Q1MA 2CM7A 1C87A 1AAXA 2HNQA 2HB1A 2A8BA 2OC3A 1YTWA 2GJTA 3EU0A 1ONZA 4NWFA 1C84A 4HRFA 4GE6A 1BZJA 5IBMA 1NL9A 1G1FA 2SHPA 2I6IA 5AWXA 1ECVA 3D1QA 4NX8A 4R30A 4MBBA 2QCJA 1ZC0A 2B4PA 2GP0A 2HVLA 2CNHA 2B07A 5BX1A 1XXVA 4ZN5A 3I7ZA 2F6WA 3MOWA 3QCKA 1XRIA 3S3KA 4QBEA 2I1YA 2FH7A 4QAPA 2B3OA 3S3EA 1EENA 1G7GA 1Q6PA 4GFUA 5KA1A 3PS5A 2NV5A 5EHRA 1GFYA 3QCHA 1JLNA 1G4US 2PA5A 2Q05A 1NNYA 4RI4A 3S3HA 4HJQA 1NZ7A 2H4VA 1GWZA 5I6VA 2I4HA 1Q6SA 2MBCA 3N0AA 3RO1A 5K24A 1J4XA 1EEOA 4WOHA 4GRZA 3EB1A 5GTJA 2A3KA 2I3UA 2F6TA 1ZZWA 5M43A 3SR9A 5KA2A 2PQ5A 2FJMA 1YPTA 1ZCLA 2WGPA 1I9SA 1PXHA 2H4KA 1PH0A 1G1HA 1XXPA 3I80A 1OEVA 2F6YA 1G1GA 3QCDA 5KA9A 5K25A 4QUNA 2PBNA 2QBPA 3RGOA 4JNBA 4WU3A 3D42A 3B7OA 1YTNA 3MMJA 1SUGA 2F6FA 2F70A 2DXPA 3O4TA 2NLKA 3CM3A 3V0JA 1FPRA 2VEWA 1G4WR 2I6MA 3BLUA 3V0IA 2HC1A 3RZ2A 2OUDA 2PSZA 3D1HA 3F9BA 4YR8B 3S3FA 5KA4A 3S4OA 3QCEA 3U96A 3ZMPA 1YFOA 1JF7A 5BUGA 5LXQB 3OLRA 5KAAA 3RGQA 3QCBA 2CFVA 2NT2A 2IMGA 2P4DA 1RPMA 2CM8A 4JMJA 4GE5A 4GE2A 1YZ4A 4D3RA 2VEUA 1PTYA 5MMZB 3ZV2A 4ZI4A 1LARA 1V3AA 1PA9A 4B04A 2F71A 4QBWA 3EMUA 1Q6NA 3O4UA 2HCMA 1OESA 2G59A 5KA0A 1NWLA 2I42A 5K23A 2QEPA 4IKCA 4GRYA 2HC2A 4R0TA 1YGUA 1T49A 2C46A 1C86A 3GXGA 4HJPA 1Q6TA 5KA8A 1R6HA 2CMCA 1PA1A 2OZ5A 2I4GA 1YTSA 1FQ1A 4I8NA 1FPZA 4D3QA 3QCNA 4JBCA 2I3RA 3AWFA 4TVVA 1KAVA 2R0BA 2JJDA 3D9CA 4NYHA 5K9VA 2QBSA 3ZM0A 1T48A 2J17A 3D1OA 4BPCA 1Q6JA 1LYVA 2NT7A 4OHIA 4JMKA 4ICZA 4R0SA 1C83A 1MKPA 3S4EA 2ZN7A 5KABA 1C88A 1KAKA 3QCLA 4OHLA 4Y14A 2E0TA 2AHSA 2I6PA 3AWEA 5K9WA 1L8KA 1OEUA 2OOQA 3ZMQA 4PVGA 4OHHA 2CNFA 2QDMA 2CM2A 4BJOA 3EZZA 1PYNA 4OHEA 2CJZA 4QUMA 1OEMX 2QDCA 3I36A 4DGXA 4Y2EA 1VHRA 2AZRA 2CNEA 1YN9A 5HDEA 1RXDA 2P6XA 2H02A 5KA7A 1PTTA 3O4SA 5KADA 2B4OA 1I57A 1OETA 3V0FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J16 A;  4H1O A;  3O3L A;  1YWF A;  5IBS A;  4DGP A;  3CWE A;  5BZZ A;  1U25 A;  3QKQ A;  2RF6 A;  3V0H A;  2H03 A;  4NND A;  4ERC A;  1WRM A;  4RDD A;  1BZC A;  3QCJ A;  3QCF A;  2PT0 A;  1I9T A;  2YDU A;  2NZ6 A;  2I75 A;  3H2X A;  2I4E A;  4YAA A;  4Z6B A;  1LQF A;  1T4J A;  2QBR A;  3A5J A;  2BZL A;  2J16 B;  2I6J A;  1OHE A;  5KAC A;  2G6Z A;  2ESB A;  2FJN A;  1U24 A;  2GWO A;  3MOZ A;  2F46 A;  3BRH A;  1ZCK A;  4RH9 A;  4NWG A;  3F81 A;  4KYR A;  2Y2F A;  3V0D A;  2I6O A;  2F6Z A;  2H04 A;  2VEV A;  2CMB A;  4GFV A;  2BIJ A;  2CM3 A;  3QCC A;  4QAH A;  1PTV A;  4WU2 A;  4WTY A;  5EHP A;  3A5K A;  2BV5 A;  1U26 A;  2H4G A;  2CNI A;  1XBO A;  1OHD A;  4RHG A;  2NTA A;  2HXP A;  1X24 A;  3QCM A;  3QKP A;  3LJ8 A;  4ZRT A;  2B4U A;  1BZH A;  3EAX A;  1XM2 A;  3ZM3 A;  1D5R A;  2F6V A;  5BZX A;  1G7F A;  5J8R A;  3F99 A;  3BLT A;  3V0E A;  4AZ1 A;  2ZMM A;  3QCI A;  1QXK A;  4KYQ A;  3ZM2 A;  1OEO X;  1P15 A;  2I5X A;  2BGD A;  4S0G A;  2QBQ A;  3OMH A;  1M3G A;  1QZ0 A;  4OHD A;  4PYH A;  4H34 A;  3F9A A;  4RH5 A;  1C85 A;  1WCH A;  2B4S A;  1OHC A;  2CMA A;  2M3V A;  2Y96 A;  4RI5 A;  1ONY A;  1Q6M A;  3ZM1 A;  3QCG A;  3GXH A;  2HY3 A;  1YGR A;  1WAX A;  2B49 A;  2VEY A;  1PTU A;  2QDP A;  4KI9 A;  4RKK A;  4J51 A;  4GWF A;  3F41 A;  4D3P A;  2VEX A;  1NWE A;  3D44 A;  1A5Y A;  4GS0 A;  1NO6 A;  2QCT A;  2Q47 A;  5KA3 A;  3NME A;  2PI7 A;  3O5X A;  2BGE A;  2CNG A;  2C7S A;  3V0G A;  3M4U A;  1L8G A;  2HNP A;  5K22 A;  3BM8 A;  3AWG A;  3SME A;  1Q1M A;  2CM7 A;  1C87 A;  1AAX A;  2HNQ A;  2HB1 A;  2A8B A;  2OC3 A;  1YTW A;  2GJT A;  3EU0 A;  1ONZ A;  4NWF A;  1C84 A;  4HRF A;  4GE6 A;  1BZJ A;  5IBM A;  1NL9 A;  1G1F A;  2SHP A;  2I6I A;  5AWX A;  1ECV A;  3D1Q A;  4NX8 A;  4R30 A;  4MBB A;  2QCJ A;  1ZC0 A;  2B4P A;  2GP0 A;  2HVL A;  2CNH A;  2B07 A;  5BX1 A;  1XXV A;  4ZN5 A;  3I7Z A;  2F6W A;  3MOW A;  3QCK A;  1XRI A;  3S3K A;  4QBE A;  2I1Y A;  2FH7 A;  4QAP A;  2B3O A;  3S3E A;  1EEN A;  1G7G A;  1Q6P A;  4GFU A;  5KA1 A;  3PS5 A;  2NV5 A;  5EHR A;  1GFY A;  3QCH A;  1JLN A;  1G4U S;  2PA5 A;  2Q05 A;  1NNY A;  4RI4 A;  3S3H A;  4HJQ A;  1NZ7 A;  2H4V A;  1GWZ A;  5I6V A;  2I4H A;  1Q6S A;  2MBC A;  3N0A A;  3RO1 A;  5K24 A;  1J4X A;  1EEO A;  4WOH A;  4GRZ A;  3EB1 A;  5GTJ A;  2A3K A;  2I3U A;  2F6T A;  1ZZW A;  5M43 A;  3SR9 A;  5KA2 A;  2PQ5 A;  2FJM A;  1YPT A;  1ZCL A;  2WGP A;  1I9S A;  1PXH A;  2H4K A;  1PH0 A;  1G1H A;  1XXP A;  3I80 A;  1OEV A;  2F6Y A;  1G1G A;  3QCD A;  5KA9 A;  5K25 A;  4QUN A;  2PBN A;  2QBP A;  3RGO A;  4JNB A;  4WU3 A;  3D42 A;  3B7O A;  1YTN A;  3MMJ A;  1SUG A;  2F6F A;  2F70 A;  2DXP A;  3O4T A;  2NLK A;  3CM3 A;  3V0J A;  1FPR A;  2VEW A;  1G4W R;  2I6M A;  3BLU A;  3V0I A;  2HC1 A;  3RZ2 A;  2OUD A;  2PSZ A;  3D1H A;  3F9B A;  4YR8 B;  3S3F A;  5KA4 A;  3S4O A;  3QCE A;  3U96 A;  3ZMP A;  1YFO A;  1JF7 A;  5BUG A;  5LXQ B;  3OLR A;  5KAA A;  3RGQ A;  3QCB A;  2CFV A;  2NT2 A;  2IMG A;  2P4D A;  1RPM A;  2CM8 A;  4JMJ A;  4GE5 A;  4GE2 A;  1YZ4 A;  4D3R A;  2VEU A;  1PTY A;  5MMZ B;  3ZV2 A;  4ZI4 A;  1LAR A;  1V3A A;  1PA9 A;  4B04 A;  2F71 A;  4QBW A;  3EMU A;  1Q6N A;  3O4U A;  2HCM A;  1OES A;  2G59 A;  5KA0 A;  1NWL A;  2I42 A;  5K23 A;  2QEP A;  4IKC A;  4GRY A;  2HC2 A;  4R0T A;  1YGU A;  1T49 A;  2C46 A;  1C86 A;  3GXG A;  4HJP A;  1Q6T A;  5KA8 A;  1R6H A;  2CMC A;  1PA1 A;  2OZ5 A;  2I4G A;  1YTS A;  1FQ1 A;  4I8N A;  1FPZ A;  4D3Q A;  3QCN A;  4JBC A;  2I3R A;  3AWF A;  4TVV A;  1KAV A;  2R0B A;  2JJD A;  3D9C A;  4NYH A;  5K9V A;  2QBS A;  3ZM0 A;  1T48 A;  2J17 A;  3D1O A;  4BPC A;  1Q6J A;  1LYV A;  2NT7 A;  4OHI A;  4JMK A;  4ICZ A;  4R0S A;  1C83 A;  1MKP A;  3S4E A;  2ZN7 A;  5KAB A;  1C88 A;  1KAK A;  3QCL A;  4OHL A;  4Y14 A;  2E0T A;  2AHS A;  2I6P A;  3AWE A;  5K9W A;  1L8K A;  1OEU A;  2OOQ A;  3ZMQ A;  4PVG A;  4OHH A;  2CNF A;  2QDM A;  2CM2 A;  4BJO A;  3EZZ A;  1PYN A;  4OHE A;  2CJZ A;  4QUM A;  1OEM X;  2QDC A;  3I36 A;  4DGX A;  4Y2E A;  1VHR A;  2AZR A;  2CNE A;  1YN9 A;  5HDE A;  1RXD A;  2P6X A;  2H02 A;  5KA7 A;  1PTT A;  3O4S A;  5KAD A;  2B4O A;  1I57 A;  1OET A;  3V0F A; 
#chains in the Genus database with same CATH topology
 2J16 A;  4H1O A;  3O3L A;  1YWF A;  5IBS A;  4DGP A;  3CWE A;  5BZZ A;  1U25 A;  3QKQ A;  2RF6 A;  3V0H A;  2H03 A;  4NND A;  4ERC A;  1WRM A;  4RDD A;  1BZC A;  3QCJ A;  3QCF A;  2PT0 A;  1I9T A;  2YDU A;  2NZ6 A;  2I75 A;  4UAG A;  3H2X A;  2I4E A;  4YAA A;  4Z6B A;  1LQF A;  1T4J A;  2QBR A;  3ZL8 A;  3A5J A;  2BZL A;  2J16 B;  2I6J A;  1OHE A;  5KAC A;  2G6Z A;  2ESB A;  2FJN A;  1U24 A;  2GWO A;  3MOZ A;  2F46 A;  3BRH A;  3QCZ A;  1ZCK A;  4RH9 A;  4NWG A;  3F81 A;  4KYR A;  2Y2F A;  3V0D A;  2I6O A;  2F6Z A;  2H04 A;  2VEV A;  2CMB A;  4GFV A;  4CVK A;  2BIJ A;  2CM3 A;  2UUO A;  3QCC A;  4QAH A;  1PTV A;  4WU2 A;  3PYZ A;  4WTY A;  5EHP A;  3A5K A;  2BV5 A;  1U26 A;  2H4G A;  2CNI A;  1XBO A;  1OHD A;  4RHG A;  2NTA A;  2JFG A;  2HXP A;  1X24 A;  3QCM A;  3QKP A;  3LJ8 A;  4ZRT A;  2B4U A;  1BZH A;  3EAX A;  1XM2 A;  2GC5 A;  3ZM3 A;  1D5R A;  2F6V A;  5BZX A;  1G7F A;  5J8R A;  3F99 A;  3BLT A;  3V0E A;  2UAG A;  4AZ1 A;  2ZMM A;  3QCI A;  1QXK A;  4KYQ A;  3ZM2 A;  1OEO X;  1P15 A;  2I5X A;  2GC6 A;  2BGD A;  4S0G A;  2QBQ A;  3OMH A;  1M3G A;  1QZ0 A;  3UAG A;  4OHD A;  4PYH A;  4H34 A;  3F9A A;  4RH5 A;  3ZM6 A;  1C85 A;  1WCH A;  2B4S A;  1OHC A;  2CMA A;  2M3V A;  2Y96 A;  4RI5 A;  3ZM5 A;  1ONY A;  1Q6M A;  3ZM1 A;  2Y1O A;  3QCG A;  5A5F A;  3GXH A;  2HY3 A;  1YGR A;  5A5E A;  1WAX A;  2B49 A;  2VEY A;  1PTU A;  2XJA A;  2QDP A;  2JFH A;  4KI9 A;  4QDI A;  4RKK A;  4J51 A;  4GWF A;  3F41 A;  1FGS A;  4D3P A;  2VEX A;  1NWE A;  3D44 A;  1A5Y A;  4GS0 A;  4C13 A;  1NO6 A;  2QCT A;  2Q47 A;  5KA3 A;  3NME A;  2PI7 A;  3O5X A;  2BGE A;  2CNG A;  2C7S A;  3V0G A;  3MVN A;  3M4U A;  1L8G A;  2HNP A;  5K22 A;  3BM8 A;  3AWG A;  3SME A;  1Q1M A;  2CM7 A;  1C87 A;  1AAX A;  2HNQ A;  2F00 A;  2HB1 A;  2A8B A;  2GCA A;  2OC3 A;  1YTW A;  2GJT A;  3EU0 A;  1ONZ A;  4NWF A;  1C84 A;  4HRF A;  4GE6 A;  1BZJ A;  5IBM A;  2VOS A;  1NL9 A;  1G1F A;  2SHP A;  2I6I A;  5AWX A;  1ECV A;  3D1Q A;  4NX8 A;  4R30 A;  4MBB A;  2QCJ A;  1ZC0 A;  2B4P A;  2GP0 A;  2HVL A;  2CNH A;  2B07 A;  5BX1 A;  1XXV A;  4ZN5 A;  3I7Z A;  2F6W A;  3MOW A;  3QCK A;  1XRI A;  3S3K A;  4QBE A;  2I1Y A;  2FH7 A;  4QAP A;  2B3O A;  3S3E A;  1GQY A;  1EEN A;  1G7G A;  1Q6P A;  4GFU A;  5KA1 A;  3PS5 A;  2NV5 A;  5EHR A;  1GFY A;  3QCH A;  1JLN A;  1G4U S;  2PA5 A;  2XPC A;  4QF5 A;  2Q05 A;  1NNY A;  4RI4 A;  3S3H A;  4BUB A;  4HJQ A;  1NZ7 A;  2H4V A;  1GWZ A;  5I6V A;  2I4H A;  1Q6S A;  4BUC A;  2MBC A;  3N0A A;  3RO1 A;  5K24 A;  1J4X A;  1EEO A;  2Y66 A;  4WOH A;  1EEH A;  4GRZ A;  3EB1 A;  5GTJ A;  2A3K A;  2I3U A;  2F6T A;  1ZZW A;  5M43 A;  3SR9 A;  5KA2 A;  2GCB A;  2PQ5 A;  2FJM A;  1YPT A;  1ZCL A;  2WGP A;  1I9S A;  1PXH A;  2AM2 A;  2H4K A;  1O5Z A;  1PH0 A;  1G1H A;  1XXP A;  2VOR A;  3I80 A;  4ZIY A;  1OEV A;  1JBW A;  2F6Y A;  1G1G A;  3QCD A;  5KA9 A;  5K25 A;  4QUN A;  2WTZ A;  3HN7 A;  2PBN A;  1W7K A;  2WJP A;  2QBP A;  3RGO A;  4JNB A;  4WU3 A;  3D42 A;  3B7O A;  2UUP A;  1YTN A;  3MMJ A;  1SUG A;  2F6F A;  2F70 A;  2DXP A;  1GG4 A;  3O4T A;  2NLK A;  3CM3 A;  3V0J A;  1FPR A;  2VEW A;  1G4W R;  1P3D A;  2I6M A;  3BLU A;  3V0I A;  2HC1 A;  3RZ2 A;  2OUD A;  2PSZ A;  2AM1 A;  3D1H A;  3F9B A;  4YR8 B;  3S3F A;  5KA4 A;  3S4O A;  3QCE A;  3U96 A;  3ZMP A;  1YFO A;  1JF7 A;  5BUG A;  5LXQ B;  3OLR A;  5KAA A;  3RGQ A;  3QCB A;  2CFV A;  2NT2 A;  2IMG A;  2P4D A;  1RPM A;  2CM8 A;  4JMJ A;  4GE5 A;  4GE2 A;  1YZ4 A;  4D3R A;  1PTY A;  2VEU A;  1JBV A;  5MMZ B;  3ZV2 A;  4ZI4 A;  1LAR A;  1V3A A;  1PA9 A;  4B04 A;  2F71 A;  4QBW A;  3EMU A;  1Q6N A;  3O4U A;  2HCM A;  1OES A;  2G59 A;  5KA0 A;  1NWL A;  2I42 A;  1J6U A;  5K23 A;  2QEP A;  4IKC A;  4GRY A;  2HC2 A;  1GQQ A;  4R0T A;  1UAG A;  1YGU A;  1T49 A;  2C46 A;  1C86 A;  3GXG A;  4HJP A;  1Q6T A;  1E8C A;  5KA8 A;  1R6H A;  2CMC A;  1PA1 A;  2OZ5 A;  2I4G A;  1YTS A;  2VTE A;  1FQ1 A;  4I8N A;  1FPZ A;  4D3Q A;  3QCN A;  4JBC A;  2I3R A;  3AWF A;  4TVV A;  1KAV A;  2R0B A;  2JJD A;  1W78 A;  2Y67 A;  3D9C A;  4NYH A;  5K9V A;  2QBS A;  3ZM0 A;  4C12 A;  1T48 A;  2J17 A;  3D1O A;  4BPC A;  1Q6J A;  1LYV A;  2X5O A;  2Y68 A;  2NT7 A;  4OHI A;  4JMK A;  4ICZ A;  4R0S A;  1C83 A;  1MKP A;  3S4E A;  2ZN7 A;  5KAB A;  1C88 A;  1KAK A;  3QCL A;  4OHL A;  4Y14 A;  2E0T A;  2AHS A;  2I6P A;  3AWE A;  5K9W A;  1L8K A;  1OEU A;  2OOQ A;  3ZMQ A;  4PVG A;  4OHH A;  2CNF A;  2QDM A;  2CM2 A;  4BJO A;  2JFF A;  3EZZ A;  3N2A A;  1PYN A;  4OHE A;  2CJZ A;  4QUM A;  2VTD A;  1OEM X;  2QDC A;  3I36 A;  4DGX A;  3LK7 A;  4Y2E A;  1P31 A;  1VHR A;  2AZR A;  2CNE A;  1YN9 A;  5HDE A;  1RXD A;  2P6X A;  3NRS A;  2H02 A;  1E0D A;  5KA7 A;  1PTT A;  3O4S A;  4HV4 A;  5KAD A;  4CVM A;  2B4O A;  4CVL A;  1I57 A;  1OET A;  3V0F A; 
#chains in the Genus database with same CATH homology
 2J16 A;  4H1O A;  3O3L A;  1YWF A;  5IBS A;  4DGP A;  3CWE A;  5BZZ A;  1U25 A;  3QKQ A;  2RF6 A;  3V0H A;  2H03 A;  4NND A;  4ERC A;  1WRM A;  4RDD A;  1BZC A;  3QCJ A;  3QCF A;  2PT0 A;  1I9T A;  2YDU A;  2NZ6 A;  2I75 A;  3H2X A;  2I4E A;  4YAA A;  4Z6B A;  1LQF A;  1T4J A;  2QBR A;  3A5J A;  2BZL A;  2J16 B;  2I6J A;  1OHE A;  5KAC A;  2G6Z A;  2ESB A;  2FJN A;  1U24 A;  2GWO A;  3MOZ A;  2F46 A;  3BRH A;  1ZCK A;  4RH9 A;  4NWG A;  3F81 A;  4KYR A;  2Y2F A;  3V0D A;  2I6O A;  2F6Z A;  2H04 A;  2VEV A;  2CMB A;  4GFV A;  2BIJ A;  2CM3 A;  3QCC A;  4QAH A;  1PTV A;  4WU2 A;  4WTY A;  5EHP A;  3A5K A;  2BV5 A;  1U26 A;  2H4G A;  2CNI A;  1XBO A;  1OHD A;  4RHG A;  2NTA A;  2HXP A;  1X24 A;  3QCM A;  3QKP A;  3LJ8 A;  4ZRT A;  2B4U A;  1BZH A;  3EAX A;  1XM2 A;  3ZM3 A;  1D5R A;  2F6V A;  5BZX A;  1G7F A;  5J8R A;  3F99 A;  3BLT A;  3V0E A;  4AZ1 A;  2ZMM A;  3QCI A;  1QXK A;  4KYQ A;  3ZM2 A;  1OEO X;  1P15 A;  2I5X A;  2BGD A;  4S0G A;  2QBQ A;  3OMH A;  1M3G A;  1QZ0 A;  4OHD A;  4PYH A;  4H34 A;  3F9A A;  4RH5 A;  1C85 A;  1WCH A;  2B4S A;  1OHC A;  2CMA A;  2M3V A;  2Y96 A;  4RI5 A;  1ONY A;  1Q6M A;  3ZM1 A;  3QCG A;  3GXH A;  2HY3 A;  1YGR A;  1WAX A;  2B49 A;  2VEY A;  1PTU A;  2QDP A;  4KI9 A;  4RKK A;  4J51 A;  4GWF A;  3F41 A;  4D3P A;  2VEX A;  1NWE A;  3D44 A;  1A5Y A;  4GS0 A;  1NO6 A;  2QCT A;  2Q47 A;  5KA3 A;  3NME A;  2PI7 A;  3O5X A;  2BGE A;  2CNG A;  2C7S A;  3V0G A;  3M4U A;  1L8G A;  2HNP A;  5K22 A;  3BM8 A;  3AWG A;  3SME A;  1Q1M A;  2CM7 A;  1C87 A;  1AAX A;  2HNQ A;  2HB1 A;  2A8B A;  2OC3 A;  1YTW A;  2GJT A;  3EU0 A;  1ONZ A;  4NWF A;  1C84 A;  4HRF A;  4GE6 A;  1BZJ A;  5IBM A;  1NL9 A;  1G1F A;  2SHP A;  2I6I A;  5AWX A;  1ECV A;  3D1Q A;  4NX8 A;  4R30 A;  4MBB A;  2QCJ A;  1ZC0 A;  2B4P A;  2GP0 A;  2HVL A;  2CNH A;  2B07 A;  5BX1 A;  1XXV A;  4ZN5 A;  3I7Z A;  2F6W A;  3MOW A;  3QCK A;  1XRI A;  3S3K A;  4QBE A;  2I1Y A;  2FH7 A;  4QAP A;  2B3O A;  3S3E A;  1EEN A;  1G7G A;  1Q6P A;  4GFU A;  5KA1 A;  3PS5 A;  2NV5 A;  5EHR A;  1GFY A;  3QCH A;  1JLN A;  1G4U S;  2PA5 A;  2Q05 A;  1NNY A;  4RI4 A;  3S3H A;  4HJQ A;  1NZ7 A;  2H4V A;  1GWZ A;  5I6V A;  2I4H A;  1Q6S A;  2MBC A;  3N0A A;  3RO1 A;  5K24 A;  1J4X A;  1EEO A;  4WOH A;  4GRZ A;  3EB1 A;  5GTJ A;  2A3K A;  2I3U A;  2F6T A;  1ZZW A;  5M43 A;  3SR9 A;  5KA2 A;  2PQ5 A;  2FJM A;  1YPT A;  1ZCL A;  2WGP A;  1I9S A;  1PXH A;  2H4K A;  1PH0 A;  1G1H A;  1XXP A;  3I80 A;  1OEV A;  2F6Y A;  1G1G A;  3QCD A;  5KA9 A;  5K25 A;  4QUN A;  2PBN A;  2QBP A;  3RGO A;  4JNB A;  4WU3 A;  3D42 A;  3B7O A;  1YTN A;  3MMJ A;  1SUG A;  2F6F A;  2F70 A;  2DXP A;  3O4T A;  2NLK A;  3CM3 A;  3V0J A;  1FPR A;  2VEW A;  1G4W R;  2I6M A;  3BLU A;  3V0I A;  2HC1 A;  3RZ2 A;  2OUD A;  2PSZ A;  3D1H A;  3F9B A;  4YR8 B;  3S3F A;  5KA4 A;  3S4O A;  3QCE A;  3U96 A;  3ZMP A;  1YFO A;  1JF7 A;  5BUG A;  5LXQ B;  3OLR A;  5KAA A;  3RGQ A;  3QCB A;  2CFV A;  2NT2 A;  2IMG A;  2P4D A;  1RPM A;  2CM8 A;  4JMJ A;  4GE5 A;  4GE2 A;  1YZ4 A;  4D3R A;  2VEU A;  1PTY A;  5MMZ B;  3ZV2 A;  4ZI4 A;  1LAR A;  1V3A A;  1PA9 A;  4B04 A;  2F71 A;  4QBW A;  3EMU A;  1Q6N A;  3O4U A;  2HCM A;  1OES A;  2G59 A;  5KA0 A;  1NWL A;  2I42 A;  5K23 A;  2QEP A;  4IKC A;  4GRY A;  2HC2 A;  4R0T A;  1YGU A;  1T49 A;  2C46 A;  1C86 A;  3GXG A;  4HJP A;  1Q6T A;  5KA8 A;  1R6H A;  2CMC A;  1PA1 A;  2OZ5 A;  2I4G A;  1YTS A;  1FQ1 A;  4I8N A;  1FPZ A;  4D3Q A;  3QCN A;  4JBC A;  2I3R A;  3AWF A;  4TVV A;  1KAV A;  2R0B A;  2JJD A;  3D9C A;  4NYH A;  5K9V A;  2QBS A;  3ZM0 A;  1T48 A;  2J17 A;  3D1O A;  4BPC A;  1Q6J A;  1LYV A;  2NT7 A;  4OHI A;  4JMK A;  4ICZ A;  4R0S A;  1C83 A;  1MKP A;  3S4E A;  2ZN7 A;  5KAB A;  1C88 A;  1KAK A;  3QCL A;  4OHL A;  4Y14 A;  2E0T A;  2AHS A;  2I6P A;  3AWE A;  5K9W A;  1L8K A;  1OEU A;  2OOQ A;  3ZMQ A;  4PVG A;  4OHH A;  2CNF A;  2QDM A;  2CM2 A;  4BJO A;  3EZZ A;  1PYN A;  4OHE A;  2CJZ A;  4QUM A;  1OEM X;  2QDC A;  3I36 A;  4DGX A;  4Y2E A;  1VHR A;  2AZR A;  2CNE A;  1YN9 A;  5HDE A;  1RXD A;  2P6X A;  2H02 A;  5KA7 A;  1PTT A;  3O4S A;  5KAD A;  2B4O A;  1I57 A;  1OET A;  3V0F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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