2GAQA

Nmr solution structure of the frb domain of mtor
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
100
structure length
100
Chain Sequence
ELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords FKBP12-rapamycin complex-associated protein
publication title The FRB Domain of mTOR: NMR Solution Structure and Inhibitor Design.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 24
structure length 100
sequence length 100
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2006-03-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08771 FRB_dom FKBP12-rapamycin binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.150 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) FKBP12-rapamycin binding domain 2gaqA00
4DRHB 2GAQA 5GPGB 1FAPB 2RSEB 1NSGB 4DRJB 4DRIB 4FAPB 3FAPB 1AUEA 2FAPB 2NPUA
chains in the Genus database with same CATH superfamily
2B0HA 2WVNA 3L34A 4KNWA 1FAPB 3FOPA 3RKOF 1NLXA 3IEEA 2DYRC 2R05A 1WGWA 4I1OB 4IAOA 3RVYA 3EZIA 4AE4A 1U0BB 1HE1A 2R7TA 3ZIBA 5DS6A 4MVOA 1WASA 5L0CA 1TFOB 3PCVA 4IRUA 4QDLA 1T01A 1JR8A 2G3VA 1LI5A 3DJNB 4JJGA 4A2NB 2WZLA 1HY5A 3CEXA 3M1CB 5L3VA 2XL4A 5E3AA 4DOZA 3TJ6A 4G7OF 3IHUA 2R7VA 1N1CA 1FMVA 1ORJA 2NUPA 4JZAA 3DE8A 5DVWA 4CDYA 3GEHA 1MQVA 3AOUA 4FWVA 3RQFA 4LLCA 5CI8A 4MVSA 1OR2A 1Q0GA 2LCHA 4NQFA 3NG1A 3N24A 5AC5A 2HV6A 2R03A 4NCQA 3B0VC 3U9JA 4YT8A 2ZD9A 4JE9A 2KNHA 4P9TA 2CNWA 3AJMA 1TQGA 2CYDA 4N6HA 4NTFA 3R2PA 4OINF 3RF3A 3TJ5A 3U8VA 4H4KC 1M2VA 1RKCA 2AWCA 1APCA 1ZHWA 2PX3A 3CAXA 4IARA 5AC4A 1MNDA 1QVXA 3M15A 5B3SC 1XZQA 1VMAA 2A68F 2BE5F 3GM2A 2Q9BA 5KYWB 5L3QA 3U3FA 2G62A 3UGOA 2L81A 2HV7A 3GM3A 4YN0B 2NG1A 4CJOA 2I8BA 4W8KA 2L6FA 4JTDB 2VB6A 2Y39A 2ETSA 2IXPA 2WZFA 4CIHA 3ABKC 3EGDB 1HW1A 2W4BA 4RDAA 3ZWIA 5T3WA 4O7GA 1K04A 1MMAA 1UFBA 1YJGA 2XLOA 2E87A 1LVKA 5A6KA 5L0FA 2YQYA 3G4XA 1D1CA 5COFA 4RD9A 1RJ9B 3VYWA 2LQGA 3IQTA 4HFKB 3QTHA 3UNGC 4MNDA 3HNJA 3U2MA 3TK0A 3S29A 1A7DA 2HKVA 4I44A 5KYXA 1V74B 3A9CA 3IQ5A 3GODA 3MYFA 5KYUB 1AUEA 4MS2A 1SR2A 2XLMA 1G8XA 2HUJA 4MTGA 4JIOA 3SZRA 2D4UA 2LD6A 3KH2A 3AG2C 2JX0A 4PJJA 1C02A 2OKUA 2IXOA 2YWAA 3T4RA 4BPMA 2XRHA 3AQCA 2KSFA 4LLEA 4Z9IA 1LE2A 2P61A 4XEFA 1ORSC 3C63A 2Y3DA 1ST6A 3KL4A 3O6XA 2XLWA 3B29A 5E2QA 4BEJA 1I4YA 2XLHA 3ABLC 4RBNA 3N2ZB 3VRCA 5KYYA 4FESA 2F22A 4WJ0A 3FOOA 3DJUB 1QSPA 4A4AA 5IY5C 2EPNA 4GQHA 3T9OA 1OXKA 1MMDA 2DB4A 4MVRA 2LP4A 4JCHA 3TULA 1S7ZA 3JRMO 3T6JA 4E0HA 1E84A 4IAQA 4QI0A 2C04A 3DKAA 1V55C 2QY9A 4U5CE 1GM5A 2PNOA 2MYSA 2OQMA 2EINC 4PJNA 2ZXWC 5DQTA 3DXJF 1J8MF 3NRHA 1WWPA 1Y6DA 4Q7CA 2Q7RA 1NG1A 4AX2A 4ANJA 5A6AA 5KYNA 3S0XA 1YVIA 1RMVA 3ZSUA 1MMNA 2IYLD 1R5ID 3ASOC 3GWNA 2R02A 1SZIA 3MYIA 3V5XA 1L3PA 3AQBA 3LAYA 2QUPA 4XEKA 2NUTB 3JT1A 2A6HF 2M64A 2QLAA 2RD9A 1HMDA 2R7XA 3AGUA 1I4ZA 4PACA 4G7ZF 3EFOB 1C17M 1C03A 2HMQA 2O9XA 3NYMA 4U9DA 2YLIA 2R9RB 4XPYA 2YKZA 2CNWD 2X0CA 4C7OA 1VYIA 1OKKA 3EQLF 4MVZA 3KMIA 1H6GA 2H7OA 3BEHA 5CI9A 2XM4A 3LS1A 3ZQYA 1Q0FA 2A0BA 2MWQA 3JTLO 1Z7Qc 1VK5A 3X1OA 2J9UA 1JOGA 3HTKC 3K33A 1RKEA 5HSWA 1ZHTA 5JUAA 3W2WA 2PFDA 3NYLA 5E3CA 1LS1A 3W8HA 2WL8A 3V5ZA 1K40A 5E33A 5JS5A 3SXKA 3MX3A 1BR2A 3HNIA 3L8IA 1QQ3A 5DLJA 4D4NA 3FAPB 5HV9A 5TJ5E 4AL0A 2J8WA 1W2WA 4FX5A 2P1AA 2Y3BA 3OEOA 4DVZA 1EKYA 1XWJA 2XM0A 4DRIB 3FMSA 2CCYA 4I3MA 1NFOA 4YL3A 3RYLA 4U9EA 1YYJA 2OU6A 1R4TA 2HFIA 4D4XA 1YZCA 2Q9CA 4J7TA 3C7JA 4WABA 2WZGA 4NTBA 3U5SA 3ZTZA 2YL1A 4DJ9A 3I5PA 3LS0A 2PF4E 4DBRA 1NSGB 3NKDA 2QE9A 1T5OA 2LK4A 3K66A 3SYNA 3R7CA 4EBBA 5DS4A 3LLKA 4MW8A 2GDCA 1NU7D 1SMYF 2IXMA 3EGXA 4JJFA 1NBBA 3T6GB 1AEPA 4YL1A 4UDVA 2XLEA 3RW0A 4XTKA 2H7BA 2PX0A 3AG3C 4JC7A 2KQ9A 2YZSA 3SXYA 2VCCA 4E7ZA 1YZAA 1I5NA 3ABMC 3C8GB 1K05A 4ONSA 1LS4A 2J9VA 4MTOA 2AU5A 1S05A 3NMKA 4C3BA 3KYJA 4BJ5C 1E86A 3J06A 3PDMP 1YYXA 3LNMB 3EG9A 4IB4A 3I5QA 3RH3A 2A1DD 2EIMC 2OCCC 1T6QA 1V54C 4X0RA 1BDJB 1Z3IX 1ORYA 3JZ0A 2EPLX 2J7PA 3K6BA 4U5FE 3SXZA 1BBHA 5FCLA 4AK9A 4HFFB 1A41A 2KC3A 2L6HA 3RFYA 2G3KA 4CS7A 4ULWA 3EJNA 1ZHXA 3CQZA 3QZCA 3QVYA 3GWLA 1Q0MA 2KK1A 1F1MA 3BRJA 3MLGA 2XS8A 4G78A 1H9TA 3DI5A 1OCZC 1Q0DA 1U89A 3C8ZA 4JTCB 3NMJA 4G0HA 4BJ5A 1M57C 2R7UA 1RCPA 2Q3TA 2YRFA 1CGME 3M79A 3V7OA 3SXMA 1JPJA 2Y3HA 3S84A 1OKKD 3U9MA 3Q7LA 4BEMJ 2PBEA 3EPVA 1FNTc 1AVOB 3G50A 4H54A 3ZDLA 3ZTMA 4C3DA 4DVYP 2QTVA 1OCRC 4EWCA 5A6BA 3G4ZA 4U5BE 1KTMA 4CDAA 3UMKA 1Y4CA 4JEBA 1ZHZA 2A0UA 3GORA 3TD7A 3C62A 5BQHA 4Q5SF 3MBGA 3A11A 2Q00A 5KYWA 5COMA 2XXAB 1V4AA 3QW1A 2J0WA 5L0IA 1G4US 3KKBA 1NZEA 4N6CA 4CJGA 5L0JA 2VASA 2XL6A 1FTSA 2LFFA 1ZW3A 3GANA 4U5HA 4N06A 3SNHA 3EGDA 4PJLA 1XZPA 1TWHA 1Z5ZA 4XQ1A 3VM6A 4YT5A 3EH2A 4OIRF 4EIYA 4CSAA 3EH1A 3B0PA 1WTYA 1Z63A 1RJ9A 2CDQA 1TWGA 2W4MA 2OOCA 1GQAA 1LI7A 2YLDA 3GEEA 4P9FA 3X2QC 2HS5A 4BJ6A 1ZVZA 5EK0A 1T6IA 4PFPA 1OCOC 2AP3A 1VTMP 3IPMO 4C7OB 3VF0A 1HE9A 3DAGA 5F28E 4E17A 2A6EF 4M63A 3GM1A 1MNEA 2P7VA 4JW1A 5KYUA 5DQZA 1PD0A 2CW0F 1TR2A 4CX9A 5L0DA 5DS5A 4R32A 4EBKA 4XLPF 1FMWA 1Q0KA 2Z15A 4OD4A 3I4UA 3ZQVA 4KNVA 1M6TA 1EI7A 2LIGA 2HZ8A 1QZXA 1E85A 5EGYA 2R7QA 1KU2A 1D1AA 4CBEA 1ZZPA 2GA0A 1ZHYA 4CS9A 4Q4ZF 3L0IA 1H7IA 4MW3A 4ZLDA 4YWQA 2HJ3A 2DI3A 3TOLA 5BQGA 2LSEA 3WG7C 4CIPA 4NTAA 3HLZA 5B1BC 3QMKA 2QNLA 1OR3A 1VB5A 4EUKB 2J7PD 2OEXA 3POVA 1TWCA 3FXHA 3JRTA 3LLIA 1CPQA 3JSEO 4IJJA 4JKVA 3H2VA 4L6RA 4AE4B 4BJ1A 2KW3C 4EHPA 2RSEB 2YL0A 3ATPA 2OJQA 256BA 2R7OA 3L1MA 5L0GA 3H2UA 3JSZA 1PCXA 1YA7O 3QW0A 1LM3B 5JSLA 3M4CA 1LE4A 4JURI 2WB7A 1LIHA 2NUPB 3FAJA 3ECSA 3JCUQ 1T9KA 1A7EA 1Z23A 1EQ1A 1OW7A 3T6BA 2NUTA 4JVSA 2BC5A 3CZ6A 3N0TA 3QVZA 2B0JA 3OWTA 3SEOA 3LUTB 3Q6MA 4F4BA 3SP1A 1KNYA 5JVEA 1OCCC 3EFOA 4OIQF 2GWWA 4BJTA 1L7CA 1TKNA 3EHMA 4BG0A 3K1IA 2IXNA 3DZAA 5A6BD 3AG1C 3LEOA 5JP7A 1M2VB 3JYYA 4XWJA 1YDIA 2ZXOA 4GEHA 4J32B 4YK5A 3Q6NA 4DRHB 2GAQA 2HJMA 1HW2A 1VLSA 3AGTA 3FVYA 5A69A 4NC3A 4PJMA 3V5YA 1J8YF 4JRZA 1PV3A 1RXQA 4N4WA 3DWWA 5BQIA 2KJGA 4G7HF 1HMOA 2J9BA 3KYIA 2YHSA 3O55A 1M2OA 2ZXRA 1BR4A 1E83A 2R7WA 3ZG1A 4LDKA 2ASRA 4FAPB 2UUIA 2V26A 1YLMA 2FAPB 4KC9A 4AL1A 2P0NA 1ZYRF 3TOMA 3CSKA 2EPKX 2DYSC 2XSEA 3FHDA 5CIVA 4OD5A 4YJWA 4Z9HA 4ZLCA 1A0BA 2IM8A 2H7VC 3LESA 4JEAA 2XS1A 2D5RB 2IOQA 2FGYA 3DE9A 3JYHA 4IGGA 1OW6A 5KYXB 1VYKA 1WATA 1LKXA 4CS8A 2ZPAA 4E7SA 3B9QA 1DOWA 4E18A 2Y69C 3ASNC 4DBQA 1NFNA 2OJED 4MQ9F 3O10A 5L0HA 4QI2A 1BZ4A 4LERA 4U5DE 3S28A 4EBJA 2JD3A 3U8PA 2YL3A 3DAFA 3IQ6A 2NSFA 3Q7GA 2JPUA 2KYHA 3LEVA 3L8JA 4LDRA 4YL0A 1QLEC 5B3IA 2R7SA 2HSBA 2C03A 2H8AA 3W2VA 1VOMA 1O3UA 4XPXA 4MVUA 2PP4A 2DGJA 1YARO 3C18A 5T1DB 4XLNF 3UMHA 3W4YA 2GFHA 2YL7A 3NDBB 2WVQA 5KYYB 5AGFA 4CSAC 3C8GA 3HNLA 3ITFA 4O6MA 1YAUO 5JT4A 4BJ6C 4XPWA 4C3EA 4OIOF 5JLIA 3F47A 1JPNA 4K0DA 1IZMA 4KBLA 4LDQA 3UR3C 4B6IA 1D0XA 3DM5A 4PFOA 5FZTA 3U0CA 2OG2A 3UGPA 4CDVA 2KGOA 5COGA 2XLDA 3DM9B 1WN0A 2Q4FA 1EA8A 1QKRA 5D92A 2HSQA 2L9JA 1TWAA 1NU9C 2AVKA 2Y3GA 3HNKA 4O6NA 3HKKA 3U3BA 3VAYA 3IQCA 3B71A 1E2XA 4WGZA 1IW7F 1CGNA 4P6IC 4NY3A 4CS9C 1OW8A 4U5GA 4Z9JA 1FFTC 3HJCA 3GEIA 3NKEA 2YVKA 2BL2A 1FR0A 1CGOA 1MMGA 2EILC 4WGYA 2FFHA 1O87A 4DRJB 4EKWA 2HMZA 3OA1A 3KPHA 4GYTA 3W8IA 4YT2A 1JAFA 4PR9A 3PMRA 1A7VA 4E0IA 2NSGA 1O5HA 1U6HA 1DOVA 3DMDA 2EIKC 4ER9A 5K0IA 4HEAJ 1BR1A 2I15A 2W45A 3PHF2 4O79A 1LPEA 3ZVRA 2IBFA 5F5FA 1WOLA 4OIPF 1RKEB 1FFHA 2A69F 2AWYA 1CPRA 3RQGA 1QPUA 2UUHA 4IWBA 1D0ZA 1ZU5A 3FDQA 1PD1A 2W9YA 2X51A 1B68A 1YA9A 2XXAA 3AG4C 1TFKB 2OEVA 1GS9A 2YEVA 3ZC4A 4MVQA 2J45A 2R25A 2LFDA 2WVOA 1OQCA 1Z6AA 2XL8A 4J7YA 4LACB 4MTFA 3U2LA 2CGEA 4K1OA 3US6A 1M56C 2Q9AA 3M4BA 3RQEA 5EHHA 4JCZA 1SF8A 3K1IC 2R7RA 4XEVA 4U5EE 3O39A 3LJBA 4J30B 4O6YA 4W8PA 5B1AC 2ZXPA 4HE8D 5F5HA 3NYJA 2VCAA 3MFNA 4YT4A 4I1MA 1GGQA 1UG7A 4KI2A 2EPMX 3EHNA 3K7DA 4MVMA 1G4WR 3WHNA 3EZHA 5BUOA 5JRAA 2J9WA 2XLVA 3S27A 2VCBA 5GPGB 3EGXB 1D1BA 2M4EA 3WAQA 4PK4A 2YLGA 3E9VA 3K1HA 3S9OA 2TMVP 2EIJC 2NPUA 3NMIA 4JTAB 4ULVA 3DD7A 3B0UX 2VH3A 1OXBA 2L7AA 1T6UA 3C8GD 2ICWG 5T3TA 1JMWA 3RIPA 3F46A 4K7BA 5A6JA 1ZW2A 2V3CC 3WODF 1D0YA 1G5ZA 3E70C 1H9GA 3UMIA 2J46A 2L6GA 2MHRA 3LNRA 1ZU4A 3EG9B 4CS8C 3S90A 1SYQA 3RVZA 1JRAA 2J0XA 2EPOA 5D91A 4DXWA 2VC9A 2P6VA 1VLTA 3TQOA 3H65A
chains in the Genus database with same CATH topology
4DRHB 2GAQA 5GPGB 1FAPB 2RSEB 1NSGB 4DRJB 4DRIB 4FAPB 3FAPB 1AUEA 2FAPB 2NPUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DRH B;  2GAQ A;  5GPG B;  1FAP B;  2RSE B;  1NSG B;  4DRJ B;  4DRI B;  4FAP B;  3FAP B;  1AUE A;  2FAP B;  2NPU A; 
#chains in the Genus database with same CATH topology
 2B0H A;  2WVN A;  3L34 A;  4KNW A;  1FAP B;  3FOP A;  3RKO F;  1NLX A;  3IEE A;  2DYR C;  2R05 A;  1WGW A;  4I1O B;  4IAO A;  3RVY A;  3EZI A;  4AE4 A;  1U0B B;  1HE1 A;  2R7T A;  3ZIB A;  5DS6 A;  4MVO A;  1WAS A;  5L0C A;  1TFO B;  3PCV A;  4IRU A;  4QDL A;  1T01 A;  1JR8 A;  2G3V A;  1LI5 A;  3DJN B;  4JJG A;  4A2N B;  2WZL A;  1HY5 A;  3CEX A;  3M1C B;  5L3V A;  2XL4 A;  5E3A A;  4DOZ A;  3TJ6 A;  4G7O F;  3IHU A;  2R7V A;  1N1C A;  1FMV A;  1ORJ A;  2NUP A;  4JZA A;  3DE8 A;  5DVW A;  4CDY A;  3GEH A;  1MQV A;  3AOU A;  4FWV A;  3RQF A;  4LLC A;  5CI8 A;  4MVS A;  1OR2 A;  1Q0G A;  2LCH A;  4NQF A;  3NG1 A;  3N24 A;  5AC5 A;  2HV6 A;  2R03 A;  4NCQ A;  3B0V C;  3U9J A;  4YT8 A;  2ZD9 A;  4JE9 A;  2KNH A;  4P9T A;  2CNW A;  3AJM A;  1TQG A;  2CYD A;  4N6H A;  4NTF A;  3R2P A;  4OIN F;  3RF3 A;  3TJ5 A;  3U8V A;  4H4K C;  1M2V A;  1RKC A;  2AWC A;  1APC A;  1ZHW A;  2PX3 A;  3CAX A;  4IAR A;  5AC4 A;  1MND A;  1QVX A;  3M15 A;  5B3S C;  1XZQ A;  1VMA A;  2A68 F;  2BE5 F;  3GM2 A;  2Q9B A;  5KYW B;  5L3Q A;  3U3F A;  2G62 A;  3UGO A;  2L81 A;  2HV7 A;  3GM3 A;  4YN0 B;  2NG1 A;  4CJO A;  2I8B A;  4W8K A;  2L6F A;  4JTD B;  2VB6 A;  2Y39 A;  2ETS A;  2IXP A;  2WZF A;  4CIH A;  3ABK C;  3EGD B;  1HW1 A;  2W4B A;  4RDA A;  3ZWI A;  5T3W A;  4O7G A;  1K04 A;  1MMA A;  1UFB A;  1YJG A;  2XLO A;  2E87 A;  1LVK A;  5A6K A;  5L0F A;  2YQY A;  3G4X A;  1D1C A;  5COF A;  4RD9 A;  1RJ9 B;  3VYW A;  2LQG A;  3IQT A;  4HFK B;  3QTH A;  3UNG C;  4MND A;  3HNJ A;  3U2M A;  3TK0 A;  3S29 A;  1A7D A;  2HKV A;  4I44 A;  5KYX A;  1V74 B;  3A9C A;  3IQ5 A;  3GOD A;  3MYF A;  5KYU B;  1AUE A;  4MS2 A;  1SR2 A;  2XLM A;  1G8X A;  2HUJ A;  4MTG A;  4JIO A;  3SZR A;  2D4U A;  2LD6 A;  3KH2 A;  3AG2 C;  2JX0 A;  4PJJ A;  1C02 A;  2OKU A;  2IXO A;  2YWA A;  3T4R A;  4BPM A;  2XRH A;  3AQC A;  2KSF A;  4LLE A;  4Z9I A;  1LE2 A;  2P61 A;  4XEF A;  1ORS C;  3C63 A;  2Y3D A;  1ST6 A;  3KL4 A;  3O6X A;  2XLW A;  3B29 A;  5E2Q A;  4BEJ A;  1I4Y A;  2XLH A;  3ABL C;  4RBN A;  3N2Z B;  3VRC A;  5KYY A;  4FES A;  2F22 A;  4WJ0 A;  3FOO A;  3DJU B;  1QSP A;  4A4A A;  5IY5 C;  2EPN A;  4GQH A;  3T9O A;  1OXK A;  1MMD A;  2DB4 A;  4MVR A;  2LP4 A;  4JCH A;  3TUL A;  1S7Z A;  3JRM O;  3T6J A;  4E0H A;  1E84 A;  4IAQ A;  4QI0 A;  2C04 A;  3DKA A;  1V55 C;  2QY9 A;  4U5C E;  1GM5 A;  2PNO A;  2MYS A;  2OQM A;  2EIN C;  4PJN A;  2ZXW C;  5DQT A;  3DXJ F;  1J8M F;  3NRH A;  1WWP A;  1Y6D A;  4Q7C A;  2Q7R A;  1NG1 A;  4AX2 A;  4ANJ A;  5A6A A;  5KYN A;  3S0X A;  1YVI A;  1RMV A;  3ZSU A;  1MMN A;  2IYL D;  1R5I D;  3ASO C;  3GWN A;  2R02 A;  1SZI A;  3MYI A;  3V5X A;  1L3P A;  3AQB A;  3LAY A;  2QUP A;  4XEK A;  2NUT B;  3JT1 A;  2A6H F;  2M64 A;  2QLA A;  2RD9 A;  1HMD A;  2R7X A;  3AGU A;  1I4Z A;  4PAC A;  4G7Z F;  3EFO B;  1C17 M;  1C03 A;  2HMQ A;  2O9X A;  3NYM A;  4U9D A;  2YLI A;  2R9R B;  4XPY A;  2YKZ A;  2CNW D;  2X0C A;  4C7O A;  1VYI A;  1OKK A;  3EQL F;  4MVZ A;  3KMI A;  1H6G A;  2H7O A;  3BEH A;  5CI9 A;  2XM4 A;  3LS1 A;  3ZQY A;  1Q0F A;  2A0B A;  2MWQ A;  3JTL O;  1Z7Q c;  1VK5 A;  3X1O A;  2J9U A;  1JOG A;  3HTK C;  3K33 A;  1RKE A;  5HSW A;  1ZHT A;  5JUA A;  3W2W A;  2PFD A;  3NYL A;  5E3C A;  1LS1 A;  3W8H A;  2WL8 A;  3V5Z A;  1K40 A;  5E33 A;  5JS5 A;  3SXK A;  3MX3 A;  1BR2 A;  3HNI A;  3L8I A;  1QQ3 A;  5DLJ A;  4D4N A;  3FAP B;  5HV9 A;  5TJ5 E;  4AL0 A;  2J8W A;  1W2W A;  4FX5 A;  2P1A A;  2Y3B A;  3OEO A;  4DVZ A;  1EKY A;  1XWJ A;  2XM0 A;  4DRI B;  3FMS A;  2CCY A;  4I3M A;  1NFO A;  4YL3 A;  3RYL A;  4U9E A;  1YYJ A;  2OU6 A;  1R4T A;  2HFI A;  4D4X A;  1YZC A;  2Q9C A;  4J7T A;  3C7J A;  4WAB A;  2WZG A;  4NTB A;  3U5S A;  3ZTZ A;  2YL1 A;  4DJ9 A;  3I5P A;  3LS0 A;  2PF4 E;  4DBR A;  1NSG B;  3NKD A;  2QE9 A;  1T5O A;  2LK4 A;  3K66 A;  3SYN A;  3R7C A;  4EBB A;  5DS4 A;  3LLK A;  4MW8 A;  2GDC A;  1NU7 D;  1SMY F;  2IXM A;  3EGX A;  4JJF A;  1NBB A;  3T6G B;  1AEP A;  4YL1 A;  4UDV A;  2XLE A;  3RW0 A;  4XTK A;  2H7B A;  2PX0 A;  3AG3 C;  4JC7 A;  2KQ9 A;  2YZS A;  3SXY A;  2VCC A;  4E7Z A;  1YZA A;  1I5N A;  3ABM C;  3C8G B;  1K05 A;  4ONS A;  1LS4 A;  2J9V A;  4MTO A;  2AU5 A;  1S05 A;  3NMK A;  4C3B A;  3KYJ A;  4BJ5 C;  1E86 A;  3J06 A;  3PDM P;  1YYX A;  3LNM B;  3EG9 A;  4IB4 A;  3I5Q A;  3RH3 A;  2A1D D;  2EIM C;  2OCC C;  1T6Q A;  1V54 C;  4X0R A;  1BDJ B;  1Z3I X;  1ORY A;  3JZ0 A;  2EPL X;  2J7P A;  3K6B A;  4U5F E;  3SXZ A;  1BBH A;  5FCL A;  4AK9 A;  4HFF B;  1A41 A;  2KC3 A;  2L6H A;  3RFY A;  2G3K A;  4CS7 A;  4ULW A;  3EJN A;  1ZHX A;  3CQZ A;  3QZC A;  3QVY A;  3GWL A;  1Q0M A;  2KK1 A;  1F1M A;  3BRJ A;  3MLG A;  2XS8 A;  4G78 A;  1H9T A;  3DI5 A;  1OCZ C;  1Q0D A;  1U89 A;  3C8Z A;  4JTC B;  3NMJ A;  4G0H A;  4BJ5 A;  1M57 C;  2R7U A;  1RCP A;  2Q3T A;  2YRF A;  1CGM E;  3M79 A;  3V7O A;  3SXM A;  1JPJ A;  2Y3H A;  3S84 A;  1OKK D;  3U9M A;  3Q7L A;  4BEM J;  2PBE A;  3EPV A;  1FNT c;  1AVO B;  3G50 A;  4H54 A;  3ZDL A;  3ZTM A;  4C3D A;  4DVY P;  2QTV A;  1OCR C;  4EWC A;  5A6B A;  3G4Z A;  4U5B E;  1KTM A;  4CDA A;  3UMK A;  1Y4C A;  4JEB A;  1ZHZ A;  2A0U A;  3GOR A;  3TD7 A;  3C62 A;  5BQH A;  4Q5S F;  3MBG A;  3A11 A;  2Q00 A;  5KYW A;  5COM A;  2XXA B;  1V4A A;  3QW1 A;  2J0W A;  5L0I A;  1G4U S;  3KKB A;  1NZE A;  4N6C A;  4CJG A;  5L0J A;  2VAS A;  2XL6 A;  1FTS A;  2LFF A;  1ZW3 A;  3GAN A;  4U5H A;  4N06 A;  3SNH A;  3EGD A;  4PJL A;  1XZP A;  1TWH A;  1Z5Z A;  4XQ1 A;  3VM6 A;  4YT5 A;  3EH2 A;  4OIR F;  4EIY A;  4CSA A;  3EH1 A;  3B0P A;  1WTY A;  1Z63 A;  1RJ9 A;  2CDQ A;  1TWG A;  2W4M A;  2OOC A;  1GQA A;  1LI7 A;  2YLD A;  3GEE A;  4P9F A;  3X2Q C;  2HS5 A;  4BJ6 A;  1ZVZ A;  5EK0 A;  1T6I A;  4PFP A;  1OCO C;  2AP3 A;  1VTM P;  3IPM O;  4C7O B;  3VF0 A;  1HE9 A;  3DAG A;  5F28 E;  4E17 A;  2A6E F;  4M63 A;  3GM1 A;  1MNE A;  2P7V A;  4JW1 A;  5KYU A;  5DQZ A;  1PD0 A;  2CW0 F;  1TR2 A;  4CX9 A;  5L0D A;  5DS5 A;  4R32 A;  4EBK A;  4XLP F;  1FMW A;  1Q0K A;  2Z15 A;  4OD4 A;  3I4U A;  3ZQV A;  4KNV A;  1M6T A;  1EI7 A;  2LIG A;  2HZ8 A;  1QZX A;  1E85 A;  5EGY A;  2R7Q A;  1KU2 A;  1D1A A;  4CBE A;  1ZZP A;  2GA0 A;  1ZHY A;  4CS9 A;  4Q4Z F;  3L0I A;  1H7I A;  4MW3 A;  4ZLD A;  4YWQ A;  2HJ3 A;  2DI3 A;  3TOL A;  5BQG A;  2LSE A;  3WG7 C;  4CIP A;  4NTA A;  3HLZ A;  5B1B C;  3QMK A;  2QNL A;  1OR3 A;  1VB5 A;  4EUK B;  2J7P D;  2OEX A;  3POV A;  1TWC A;  3FXH A;  3JRT A;  3LLI A;  1CPQ A;  3JSE O;  4IJJ A;  4JKV A;  3H2V A;  4L6R A;  4AE4 B;  4BJ1 A;  2KW3 C;  4EHP A;  2RSE B;  2YL0 A;  3ATP A;  2OJQ A;  256B A;  2R7O A;  3L1M A;  5L0G A;  3H2U A;  3JSZ A;  1PCX A;  1YA7 O;  3QW0 A;  1LM3 B;  5JSL A;  3M4C A;  1LE4 A;  4JUR I;  2WB7 A;  1LIH A;  2NUP B;  3FAJ A;  3ECS A;  3JCU Q;  1T9K A;  1A7E A;  1Z23 A;  1EQ1 A;  1OW7 A;  3T6B A;  2NUT A;  4JVS A;  2BC5 A;  3CZ6 A;  3N0T A;  3QVZ A;  2B0J A;  3OWT A;  3SEO A;  3LUT B;  3Q6M A;  4F4B A;  3SP1 A;  1KNY A;  5JVE A;  1OCC C;  3EFO A;  4OIQ F;  2GWW A;  4BJT A;  1L7C A;  1TKN A;  3EHM A;  4BG0 A;  3K1I A;  2IXN A;  3DZA A;  5A6B D;  3AG1 C;  3LEO A;  5JP7 A;  1M2V B;  3JYY A;  4XWJ A;  1YDI A;  2ZXO A;  4GEH A;  4J32 B;  4YK5 A;  3Q6N A;  4DRH B;  2GAQ A;  2HJM A;  1HW2 A;  1VLS A;  3AGT A;  3FVY A;  5A69 A;  4NC3 A;  4PJM A;  3V5Y A;  1J8Y F;  4JRZ A;  1PV3 A;  1RXQ A;  4N4W A;  3DWW A;  5BQI A;  2KJG A;  4G7H F;  1HMO A;  2J9B A;  3KYI A;  2YHS A;  3O55 A;  1M2O A;  2ZXR A;  1BR4 A;  1E83 A;  2R7W A;  3ZG1 A;  4LDK A;  2ASR A;  4FAP B;  2UUI A;  2V26 A;  1YLM A;  2FAP B;  4KC9 A;  4AL1 A;  2P0N A;  1ZYR F;  3TOM A;  3CSK A;  2EPK X;  2DYS C;  2XSE A;  3FHD A;  5CIV A;  4OD5 A;  4YJW A;  4Z9H A;  4ZLC A;  1A0B A;  2IM8 A;  2H7V C;  3LES A;  4JEA A;  2XS1 A;  2D5R B;  2IOQ A;  2FGY A;  3DE9 A;  3JYH A;  4IGG A;  1OW6 A;  5KYX B;  1VYK A;  1WAT A;  1LKX A;  4CS8 A;  2ZPA A;  4E7S A;  3B9Q A;  1DOW A;  4E18 A;  2Y69 C;  3ASN C;  4DBQ A;  1NFN A;  2OJE D;  4MQ9 F;  3O10 A;  5L0H A;  4QI2 A;  1BZ4 A;  4LER A;  4U5D E;  3S28 A;  4EBJ A;  2JD3 A;  3U8P A;  2YL3 A;  3DAF A;  3IQ6 A;  2NSF A;  3Q7G A;  2JPU A;  2KYH A;  3LEV A;  3L8J A;  4LDR A;  4YL0 A;  1QLE C;  5B3I A;  2R7S A;  2HSB A;  2C03 A;  2H8A A;  3W2V A;  1VOM A;  1O3U A;  4XPX A;  4MVU A;  2PP4 A;  2DGJ A;  1YAR O;  3C18 A;  5T1D B;  4XLN F;  3UMH A;  3W4Y A;  2GFH A;  2YL7 A;  3NDB B;  2WVQ A;  5KYY B;  5AGF A;  4CSA C;  3C8G A;  3HNL A;  3ITF A;  4O6M A;  1YAU O;  5JT4 A;  4BJ6 C;  4XPW A;  4C3E A;  4OIO F;  5JLI A;  3F47 A;  1JPN A;  4K0D A;  1IZM A;  4KBL A;  4LDQ A;  3UR3 C;  4B6I A;  1D0X A;  3DM5 A;  4PFO A;  5FZT A;  3U0C A;  2OG2 A;  3UGP A;  4CDV A;  2KGO A;  5COG A;  2XLD A;  3DM9 B;  1WN0 A;  2Q4F A;  1EA8 A;  1QKR A;  5D92 A;  2HSQ A;  2L9J A;  1TWA A;  1NU9 C;  2AVK A;  2Y3G A;  3HNK A;  4O6N A;  3HKK A;  3U3B A;  3VAY A;  3IQC A;  3B71 A;  1E2X A;  4WGZ A;  1IW7 F;  1CGN A;  4P6I C;  4NY3 A;  4CS9 C;  1OW8 A;  4U5G A;  4Z9J A;  1FFT C;  3HJC A;  3GEI A;  3NKE A;  2YVK A;  2BL2 A;  1FR0 A;  1CGO A;  1MMG A;  2EIL C;  4WGY A;  2FFH A;  1O87 A;  4DRJ B;  4EKW A;  2HMZ A;  3OA1 A;  3KPH A;  4GYT A;  3W8I A;  4YT2 A;  1JAF A;  4PR9 A;  3PMR A;  1A7V A;  4E0I A;  2NSG A;  1O5H A;  1U6H A;  1DOV A;  3DMD A;  2EIK C;  4ER9 A;  5K0I A;  4HEA J;  1BR1 A;  2I15 A;  2W45 A;  3PHF 2;  4O79 A;  1LPE A;  3ZVR A;  2IBF A;  5F5F A;  1WOL A;  4OIP F;  1RKE B;  1FFH A;  2A69 F;  2AWY A;  1CPR A;  3RQG A;  1QPU A;  2UUH A;  4IWB A;  1D0Z A;  1ZU5 A;  3FDQ A;  1PD1 A;  2W9Y A;  2X51 A;  1B68 A;  1YA9 A;  2XXA A;  3AG4 C;  1TFK B;  2OEV A;  1GS9 A;  2YEV A;  3ZC4 A;  4MVQ A;  2J45 A;  2R25 A;  2LFD A;  2WVO A;  1OQC A;  1Z6A A;  2XL8 A;  4J7Y A;  4LAC B;  4MTF A;  3U2L A;  2CGE A;  4K1O A;  3US6 A;  1M56 C;  2Q9A A;  3M4B A;  3RQE A;  5EHH A;  4JCZ A;  1SF8 A;  3K1I C;  2R7R A;  4XEV A;  4U5E E;  3O39 A;  3LJB A;  4J30 B;  4O6Y A;  4W8P A;  5B1A C;  2ZXP A;  4HE8 D;  5F5H A;  3NYJ A;  2VCA A;  3MFN A;  4YT4 A;  4I1M A;  1GGQ A;  1UG7 A;  4KI2 A;  2EPM X;  3EHN A;  3K7D A;  4MVM A;  1G4W R;  3WHN A;  3EZH A;  5BUO A;  5JRA A;  2J9W A;  2XLV A;  3S27 A;  2VCB A;  5GPG B;  3EGX B;  1D1B A;  2M4E A;  3WAQ A;  4PK4 A;  2YLG A;  3E9V A;  3K1H A;  3S9O A;  2TMV P;  2EIJ C;  2NPU A;  3NMI A;  4JTA B;  4ULV A;  3DD7 A;  3B0U X;  2VH3 A;  1OXB A;  2L7A A;  1T6U A;  3C8G D;  2ICW G;  5T3T A;  1JMW A;  3RIP A;  3F46 A;  4K7B A;  5A6J A;  1ZW2 A;  2V3C C;  3WOD F;  1D0Y A;  1G5Z A;  3E70 C;  1H9G A;  3UMI A;  2J46 A;  2L6G A;  2MHR A;  3LNR A;  1ZU4 A;  3EG9 B;  4CS8 C;  3S90 A;  1SYQ A;  3RVZ A;  1JRA A;  2J0X A;  2EPO A;  5D91 A;  4DXW A;  2VC9 A;  2P6V A;  1VLT A;  3TQO A;  3H65 A; 
#chains in the Genus database with same CATH homology
 4DRH B;  2GAQ A;  5GPG B;  1FAP B;  2RSE B;  1NSG B;  4DRJ B;  4DRI B;  4FAP B;  3FAP B;  1AUE A;  2FAP B;  2NPU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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