2GO3A

Crystal structure of aquifex aeolicus lpxc complexed with imidazole.
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
266
structure length
266
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic Inferences from the Binding of Ligands to LpxC, a Metal-Dependent Deacetylase
pubmed doi rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 91
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2006-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 2go3A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 2go3A02
2IERA 1XXEA 2IESA 3PS2A 4J3DA 2VESA 3UHMA 4OKGA 4OZEA 3P3EA 5DROA 4LCHA 3P76A 3U1YA 4LCGA 3P3CA 5DRRA 4FW5A 4IS9A 4MDTA 2GO3A 3NZKA 4FW4A 4MQYA 5DRPA 4FW3A 2JT2A 1YH8A 3PS3A 5DRQA 4U3DA 4U3BA 2O3ZA 1P42A 4FW7A 4FW6A 1YHCA 2GO4A 4LCFA 3PS1A 2J65A 4ISAA 3P3GA
chains in the Genus database with same CATH superfamily
2O1TA 4PU9A 4LFBI 5BR8I 2EFGA 4DXLA 2DEIA 4GKJE 1H7SA 4DPUA 2OI2A 1VI7A 4JI6E 4MU0A 4X65E 4LF5E 2UXDE 3M6AA 4B3TE 1K47A 1U2RA 2JE6A 4MYTA 5K36C 2GO3A 2WW4A 4DU7A 2J7KA 3QT7A 2UUBI 4ED4A 5DNLA 1Y5YA 1R6MA 3QT8A 2J65A 4FN5A 2BR2A 2PO0A 3LPSA 4JI0E 4JYAI 3ZZUA 1Z5AA 4DPYA 4WUDA 1ZM4A 1N0UA 1KTVA 2IOQA 4GKKI 4P52A 3P76A 4JI2I 1IBME 2PNZB 4LF6I 3J7AG 4URLA 4OO1F 2E5LE 3Q1QA 4JI7E 4YY3E 4USKA 2UXCE 4IS9A 2JEBB 3LNUA 1UDNA 4DR4E 3B78A 2HHHE 4DV5I 1Z5BA 1J5EI 4DR1E 3CDJA 1XMOI 3PS1A 2C37A 1H72C 1PVGA 4X66E 5FLXC 3PS2A 5IT9C 5A2QQ 2HK3A 2NN6E 4HACA 2HKJA 1A6FA 1B63A 1FI4A 5DNXA 1I94I 4NBQA 4M1KA 1EA6A 1N32I 4DR5I 2F4VI 1HNWE 4DV4I 1IBKE 3KRNA 4LF7E 1H7UA 2WP8B 5DRPA 4ZVIA 1HK7A 4DR7I 1H73A 2AE8A 5LMUE 1RREA 1FJGI 2V8PA 3P3GA 4B3SI 4QNJA 3HJCA 4DR5E 2F4VE 2WNRA 4USMA 2VESA 4DV3E 4FWDA 4OX9I 3QT5A 4Z7CA 1DARA 4DR6E 5DROA 4AQYI 1D6TA 3U1YA 3H4LA 2BA0G 1RR9A 2BV3A 4K0KE 2CG9A 3P3CA 4MU1A 1Z59A 3U1KA 4DV7E 3PS3A 4U3DA 4JI4E 3M85G 4B3RE 1ZM9A 1KKHA 3QT6A 3WU3A 4AQYE 1ZXMA 3T1YE 4LFBE 2VF3A 4X64E 2Z5EA 5JEAD 4KHPI 3ZKBA 4B3MI 1N34I 3P3EA 1R6LA 3K85A 1FJGE 4IZJD 2BM1A 3JAMQ 4BA2A 2UXDI 4WUCA 4WUBA 1XNRI 5BR8E 3D4JA 1KVKA 2VQEI 3B8HA 2HHHI 4DR6I 1FNMA 2Z5BA 3B82A 3DD6A 4IFDC 2O1VA 5IT9Q 4HXZA 3OTOI 2PNZA 4IFDE 4LCFA 1HR0E 2R42A 1Z0CA 5EL9A 1OJ4A 1UEKA 1Z0TA 3GCMA 4DV2E 3P06A 3M7NG 1Z0BA 2PO0B 4KQVA 3GLLA 4HACB 4AM3A 2UXCI 3ZM7A 1XMQE 4NXNE 1PKPA 4JI2E 2Z5CB 2E1RA 4IFDA 5LL6R 5C0XC 5C0XE 4LFCI 4JV5I 1USUA 4X66I 4DR2I 4OO1D 5JEAB 1XHKA 1HNWI 1XMQI 4X64I 2XEXA 5A2QC 4EMDA 2A2DA 4DUZI 3WU5A 4MDTA 4DPXA 4DV0I 2BR2B 2O1WA 2UXBE 2UU9E 4DR7E 4DPTA 2Q2EB 2BA1D 2UUCE 3K1JA 1ELOA 4ISAA 5IWAE 4DV4E 1IBKI 1HNZI 3WU4A 2V2QA 1XNQI 4OX9E 5EKWA 4NXME 1USVA 4LF4E 2PO2A 4LF8I 4DR3I 3J80C 4PRXA 2NN6C 4LCGA 1KIJA 2PO1A 4FW4A 1S16A 1OYRA 4MU3A 1N36E 1OYSA 4LF5I 2PO1B 1YHCA 1FKAE 1Z5CA 4NXNI 4XTJA 4MYUA 3M85D 1XNQE 2CGEA 2IERA 1QZRA 1BKNA 4GKKE 1NHIA 4FW9A 4MU4A 1NHHA 1OYPA 2V34A 1HNXI 3T1HE 1MG7A 1J5EE 3ZKDA 1RHYA 3J7AM 3OTOE 2BA1G 4DR4I 4FW6A 1ZM2A 5LMNI 2UUAI 4B3SE 2X7IA 1H74A 5K36E 4JI3I 1IBMI 3Q6MA 2UUCI 4JI4I 3V2UC 4R1FA 4FWHA 5GMDA 4KHPE 2NN6A 4UTGA 2HFUA 5LMNE 4NXMI 2BA0D 1ZM3A 3WU6A 4BA1A 2NN6D 4LPFA 4YHHI 3J81C 1UDQA 5JEAF 4B3RI 4X62E 2O3ZA 4LFCE 4JV5E 4UT4A 4JI8I 2R3VA 4IFDF 2WP8A 4JYAE 4JI1I 4JI5E 3M7ND 2HK2A 4LFAI 3PRYA 2CVEA 4LF8E 5K36A 2PNLA 4QNKA 2NN6B 3H1CA 4IFDB 4IZJA 1I94E 4LF6E 3PYFA 2VQEE 4DV7I 2C37B 4DV2I 2UU9I 1P42A 4JI8E 2A2CA 5C0XA 4LF7I 2NN6F 2F1DA 4OO1C 4B3ME 4IZKB 1Y60A 4J3DA 4LF4I 2LJPA 2VQFI 1Z0WA 2ZM6E 5C0XB 1EI1A 1MU5A 4LF9I 3K17A 5IWAI 1HNXE 2X36A 3GMEA 3NZKA 4P7AA 2JT2A 2Z5BB 4DV5E 5K36F 3Q6NA 3JAMC 4JI6I 3B4TA 1HR0I 2ZITA 1Y6ZA 4DUZE 1Z0EA 4YY3I 4DU8A 1FWLA 1XXEA 2IESA 4DV3I 5ELWA 4DUYE 1UDOA 5L3JA 1ZXNA 3F0NA 3L7ZB 4JI1E 4JI5I 5K36B 2AJ4A 4LCHA 3T1HI 4B3TI 1WUUA 4X65I 1Y4SA 5JEAE 1XMOE 5FWKA 2BM0A 1VISA 4IZKA 3GONA 3HULA 5DRQA 2VQFE 4DR3E 4DUYI 1N32E 2GO4A 1IBLI 1XNRE 4FWGA 4PRVA 3J81Q 2C38B 5JEAC 1PIEA 2DEJA 2WNRB 3CWVA 3UHMA 4IZJB 3HKMA 4GKJI 4JI0I 2C39A 5LMUI 2JEAB 4DV1E 4BA2B 2O1UA 4AIDA 4DR1I 1N0VC 2ZM6I 2C38A 4RPFA 4HYMA 4YHHE 2NPFA 2CZ9A 1S4EA 1Z0VA 5JEAA 3J80Q 2JEBA 1MX0A 2C39B 2JEAA 4OO1B 4HY1A 2V2ZA 2V2VA 4DV6E 3CDIA 4BA1B 2HKEA 2GQ0A 2ZBKB 4OKGA 3L7ZA 2UUAE 1E3PA 4LF9E 1IBLE 2UUBE 3T1YI 2HFSA 2PNMA 1N33I 1B62A 1UDSA 2GS8A 5DRRA 4LOMA 4DPWA 4JG4A 4OO1E 4DR2E 1HNZE 4FW3A 2IOPA 1YH8A 4U3BA 3ZZ0A 4DV1I 5C0XF 4N3OA 4DV6I 3LTOA 2PO2B 1E3HA 4DV0E 5K36D 1Z0GA 1Y4UA 3ZZTA 1N33E 4Z7YA 4OZEA 1NZ0A 1NHJA 2Z5CA 2E5LI 4JI7I 1N36I 4LFAE 4FW5A 4MQYA 5GMEA 3PYDA 3V5RA 4K0KI 2UXBI 2JE6B 3PYGA 4X62I 1N34E 4IFDD 4FW7A 4JI3E 4I3HA 4GQUA 5FLXQ 4OO1A 3PYEA 1FWKA 5C0XD 4AIMA
chains in the Genus database with same CATH topology
2IERA 1XXEA 2IESA 3PS2A 4J3DA 2VESA 3UHMA 4OKGA 4OZEA 3P3EA 5DROA 4LCHA 3P76A 3U1YA 4LCGA 3P3CA 5DRRA 4FW5A 4IS9A 4MDTA 2GO3A 3NZKA 4FW4A 4MQYA 5DRPA 4FW3A 2JT2A 1YH8A 3PS3A 5DRQA 4U3DA 4U3BA 2O3ZA 1P42A 4FW7A 4FW6A 1YHCA 2GO4A 4LCFA 3PS1A 2J65A 4ISAA 3P3GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IER A;  1XXE A;  2IES A;  3PS2 A;  4J3D A;  2VES A;  3UHM A;  4OKG A;  4OZE A;  3P3E A;  5DRO A;  4LCH A;  3P76 A;  3U1Y A;  4LCG A;  3P3C A;  5DRR A;  4FW5 A;  4IS9 A;  4MDT A;  2GO3 A;  3NZK A;  4FW4 A;  4MQY A;  5DRP A;  4FW3 A;  2JT2 A;  1YH8 A;  3PS3 A;  5DRQ A;  4U3D A;  4U3B A;  2O3Z A;  1P42 A;  4FW7 A;  4FW6 A;  1YHC A;  2GO4 A;  4LCF A;  3PS1 A;  2J65 A;  4ISA A;  3P3G A; 
#chains in the Genus database with same CATH topology
 2O1T A;  4PU9 A;  4LFB I;  5BR8 I;  2EFG A;  4DXL A;  2DEI A;  4GKJ E;  1H7S A;  4DPU A;  2OI2 A;  1VI7 A;  4JI6 E;  4MU0 A;  4X65 E;  4LF5 E;  2UXD E;  3M6A A;  4B3T E;  1K47 A;  1U2R A;  2JE6 A;  4MYT A;  5K36 C;  2GO3 A;  2WW4 A;  4DU7 A;  2J7K A;  3QT7 A;  2UUB I;  4ED4 A;  5DNL A;  1Y5Y A;  1R6M A;  3QT8 A;  2J65 A;  4FN5 A;  2BR2 A;  2PO0 A;  3LPS A;  4JI0 E;  4JYA I;  3ZZU A;  1Z5A A;  4DPY A;  4WUD A;  1ZM4 A;  1N0U A;  1KTV A;  2IOQ A;  4GKK I;  4P52 A;  3P76 A;  4JI2 I;  1IBM E;  2PNZ B;  4LF6 I;  3J7A G;  4URL A;  4OO1 F;  2E5L E;  3Q1Q A;  4JI7 E;  4YY3 E;  4USK A;  2UXC E;  4IS9 A;  2JEB B;  3LNU A;  1UDN A;  4DR4 E;  3B78 A;  2HHH E;  4DV5 I;  1Z5B A;  1J5E I;  4DR1 E;  3CDJ A;  1XMO I;  3PS1 A;  2C37 A;  1H72 C;  1PVG A;  4X66 E;  5FLX C;  3PS2 A;  5IT9 C;  5A2Q Q;  2HK3 A;  2NN6 E;  4HAC A;  2HKJ A;  1A6F A;  1B63 A;  1FI4 A;  5DNX A;  1I94 I;  4NBQ A;  4M1K A;  1EA6 A;  1N32 I;  4DR5 I;  2F4V I;  1HNW E;  4DV4 I;  1IBK E;  3KRN A;  4LF7 E;  1H7U A;  2WP8 B;  5DRP A;  4ZVI A;  1HK7 A;  4DR7 I;  1H73 A;  2AE8 A;  5LMU E;  1RRE A;  1FJG I;  2V8P A;  3P3G A;  4B3S I;  4QNJ A;  3HJC A;  4DR5 E;  2F4V E;  2WNR A;  4USM A;  2VES A;  4DV3 E;  4FWD A;  4OX9 I;  3QT5 A;  4Z7C A;  1DAR A;  4DR6 E;  5DRO A;  4AQY I;  1D6T A;  3U1Y A;  3H4L A;  2BA0 G;  1RR9 A;  2BV3 A;  4K0K E;  2CG9 A;  3P3C A;  4MU1 A;  1Z59 A;  3U1K A;  4DV7 E;  3PS3 A;  4U3D A;  4JI4 E;  3M85 G;  4B3R E;  1ZM9 A;  1KKH A;  3QT6 A;  3WU3 A;  4AQY E;  1ZXM A;  3T1Y E;  4LFB E;  2VF3 A;  4X64 E;  2Z5E A;  5JEA D;  4KHP I;  3ZKB A;  4B3M I;  1N34 I;  3P3E A;  1R6L A;  3K85 A;  1FJG E;  4IZJ D;  2BM1 A;  3JAM Q;  4BA2 A;  2UXD I;  4WUC A;  4WUB A;  1XNR I;  5BR8 E;  3D4J A;  1KVK A;  2VQE I;  3B8H A;  2HHH I;  4DR6 I;  1FNM A;  2Z5B A;  3B82 A;  3DD6 A;  4IFD C;  2O1V A;  5IT9 Q;  4HXZ A;  3OTO I;  2PNZ A;  4IFD E;  4LCF A;  1HR0 E;  2R42 A;  1Z0C A;  5EL9 A;  1OJ4 A;  1UEK A;  1Z0T A;  3GCM A;  4DV2 E;  3P06 A;  3M7N G;  1Z0B A;  2PO0 B;  4KQV A;  3GLL A;  4HAC B;  4AM3 A;  2UXC I;  3ZM7 A;  1XMQ E;  4NXN E;  1PKP A;  4JI2 E;  2Z5C B;  2E1R A;  4IFD A;  5LL6 R;  5C0X C;  5C0X E;  4LFC I;  4JV5 I;  1USU A;  4X66 I;  4DR2 I;  4OO1 D;  5JEA B;  1XHK A;  1HNW I;  1XMQ I;  4X64 I;  2XEX A;  5A2Q C;  4EMD A;  2A2D A;  4DUZ I;  3WU5 A;  4MDT A;  4DPX A;  4DV0 I;  2BR2 B;  2O1W A;  2UXB E;  2UU9 E;  4DR7 E;  4DPT A;  2Q2E B;  2BA1 D;  2UUC E;  3K1J A;  1ELO A;  4ISA A;  5IWA E;  4DV4 E;  1IBK I;  1HNZ I;  3WU4 A;  2V2Q A;  1XNQ I;  4OX9 E;  5EKW A;  4NXM E;  1USV A;  4LF4 E;  2PO2 A;  4LF8 I;  4DR3 I;  3J80 C;  4PRX A;  2NN6 C;  4LCG A;  1KIJ A;  2PO1 A;  4FW4 A;  1S16 A;  1OYR A;  4MU3 A;  1N36 E;  1OYS A;  4LF5 I;  2PO1 B;  1YHC A;  1FKA E;  1Z5C A;  4NXN I;  4XTJ A;  4MYU A;  3M85 D;  1XNQ E;  2CGE A;  2IER A;  1QZR A;  1BKN A;  4GKK E;  1NHI A;  4FW9 A;  4MU4 A;  1NHH A;  1OYP A;  2V34 A;  1HNX I;  3T1H E;  1MG7 A;  1J5E E;  3ZKD A;  1RHY A;  3J7A M;  3OTO E;  2BA1 G;  4DR4 I;  4FW6 A;  1ZM2 A;  5LMN I;  2UUA I;  4B3S E;  2X7I A;  1H74 A;  5K36 E;  4JI3 I;  1IBM I;  3Q6M A;  2UUC I;  4JI4 I;  3V2U C;  4R1F A;  4FWH A;  5GMD A;  4KHP E;  2NN6 A;  4UTG A;  2HFU A;  5LMN E;  4NXM I;  2BA0 D;  1ZM3 A;  3WU6 A;  4BA1 A;  2NN6 D;  4LPF A;  4YHH I;  3J81 C;  1UDQ A;  5JEA F;  4B3R I;  4X62 E;  2O3Z A;  4LFC E;  4JV5 E;  4UT4 A;  4JI8 I;  2R3V A;  4IFD F;  2WP8 A;  4JYA E;  4JI1 I;  4JI5 E;  3M7N D;  2HK2 A;  4LFA I;  3PRY A;  2CVE A;  4LF8 E;  5K36 A;  2PNL A;  4QNK A;  2NN6 B;  3H1C A;  4IFD B;  4IZJ A;  1I94 E;  4LF6 E;  3PYF A;  2VQE E;  4DV7 I;  2C37 B;  4DV2 I;  2UU9 I;  1P42 A;  4JI8 E;  2A2C A;  5C0X A;  4LF7 I;  2NN6 F;  2F1D A;  4OO1 C;  4B3M E;  4IZK B;  1Y60 A;  4J3D A;  4LF4 I;  2LJP A;  2VQF I;  1Z0W A;  2ZM6 E;  5C0X B;  1EI1 A;  1MU5 A;  4LF9 I;  3K17 A;  5IWA I;  1HNX E;  2X36 A;  3GME A;  3NZK A;  4P7A A;  2JT2 A;  2Z5B B;  4DV5 E;  5K36 F;  3Q6N A;  3JAM C;  4JI6 I;  3B4T A;  1HR0 I;  2ZIT A;  1Y6Z A;  4DUZ E;  1Z0E A;  4YY3 I;  4DU8 A;  1FWL A;  1XXE A;  2IES A;  4DV3 I;  5ELW A;  4DUY E;  1UDO A;  5L3J A;  1ZXN A;  3F0N A;  3L7Z B;  4JI1 E;  4JI5 I;  5K36 B;  2AJ4 A;  4LCH A;  3T1H I;  4B3T I;  1WUU A;  4X65 I;  1Y4S A;  5JEA E;  1XMO E;  5FWK A;  2BM0 A;  1VIS A;  4IZK A;  3GON A;  3HUL A;  5DRQ A;  2VQF E;  4DR3 E;  4DUY I;  1N32 E;  2GO4 A;  1IBL I;  1XNR E;  4FWG A;  4PRV A;  3J81 Q;  2C38 B;  5JEA C;  1PIE A;  2DEJ A;  2WNR B;  3CWV A;  3UHM A;  4IZJ B;  3HKM A;  4GKJ I;  4JI0 I;  2C39 A;  5LMU I;  2JEA B;  4DV1 E;  4BA2 B;  2O1U A;  4AID A;  4DR1 I;  1N0V C;  2ZM6 I;  2C38 A;  4RPF A;  4HYM A;  4YHH E;  2NPF A;  2CZ9 A;  1S4E A;  1Z0V A;  5JEA A;  3J80 Q;  2JEB A;  1MX0 A;  2C39 B;  2JEA A;  4OO1 B;  4HY1 A;  2V2Z A;  2V2V A;  4DV6 E;  3CDI A;  4BA1 B;  2HKE A;  2GQ0 A;  2ZBK B;  4OKG A;  3L7Z A;  2UUA E;  1E3P A;  4LF9 E;  1IBL E;  2UUB E;  3T1Y I;  2HFS A;  2PNM A;  1N33 I;  1B62 A;  1UDS A;  2GS8 A;  5DRR A;  4LOM A;  4DPW A;  4JG4 A;  4OO1 E;  4DR2 E;  1HNZ E;  4FW3 A;  2IOP A;  1YH8 A;  4U3B A;  3ZZ0 A;  4DV1 I;  5C0X F;  4N3O A;  4DV6 I;  3LTO A;  2PO2 B;  1E3H A;  4DV0 E;  5K36 D;  1Z0G A;  1Y4U A;  3ZZT A;  1N33 E;  4Z7Y A;  4OZE A;  1NZ0 A;  1NHJ A;  2Z5C A;  2E5L I;  4JI7 I;  1N36 I;  4LFA E;  4FW5 A;  4MQY A;  5GME A;  3PYD A;  3V5R A;  4K0K I;  2UXB I;  2JE6 B;  3PYG A;  4X62 I;  1N34 E;  4IFD D;  4FW7 A;  4JI3 E;  4I3H A;  4GQU A;  5FLX Q;  4OO1 A;  3PYE A;  1FWK A;  5C0X D;  4AIM A; 
#chains in the Genus database with same CATH homology
 2IER A;  1XXE A;  2IES A;  3PS2 A;  4J3D A;  2VES A;  3UHM A;  4OKG A;  4OZE A;  3P3E A;  5DRO A;  4LCH A;  3P76 A;  3U1Y A;  4LCG A;  3P3C A;  5DRR A;  4FW5 A;  4IS9 A;  4MDT A;  2GO3 A;  3NZK A;  4FW4 A;  4MQY A;  5DRP A;  4FW3 A;  2JT2 A;  1YH8 A;  3PS3 A;  5DRQ A;  4U3D A;  4U3B A;  2O3Z A;  1P42 A;  4FW7 A;  4FW6 A;  1YHC A;  2GO4 A;  4LCF A;  3PS1 A;  2J65 A;  4ISA A;  3P3G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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