2GO3A

Crystal structure of aquifex aeolicus lpxc complexed with imidazole.
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
266
structure length
266
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic Inferences from the Binding of Ligands to LpxC, a Metal-Dependent Deacetylase
pubmed doi rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 91
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2006-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 2go3A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 2go3A02
5DRPA 3P76A 4LCFA 4FW6A 5DROA 3UHMA 2J65A 3NZKA 4FW3A 1P42A 4LCGA 2O3ZA 1YHCA 3PS1A 4J3DA 3P3EA 5DRRA 3U1YA 1YH8A 1XXEA 2IERA 4OZEA 5DRQA 4FW4A 2JT2A 4MDTA 4U3DA 4OKGA 4FW7A 3PS3A 3P3CA 2GO3A 2IESA 2GO4A 4FW5A 4IS9A 4ISAA 2VESA 4LCHA 4U3BA 3PS2A 3P3GA 4MQYA
chains in the Genus database with same CATH superfamily
1XNQE 4NBQA 2CVEA 3F0NA 4LF5I 2E1RA 3QT6A 4DR4I 1PKPA 1H72C 4DV5E 1N0VC 4IZKA 2C38A 4DV4I 2JE6B 4DR1I 1H7UA 4WUCA 5FLXQ 4DV7I 4IFDE 2CGEA 2PNLA 4JI6E 4X62I 2HFSA 4DR6I 2PO1B 1Z0WA 3KRNA 4LF9I 2HK2A 4DU7A 4IS9A 1NZ0A 3B78A 4LCHA 1I94E 1XMQE 2V2VA 4NXMI 2BM1A 3ZZ0A 4DUZI 4JI2E 4JI1I 4DR2I 4UTGA 4DR3I 4FW3A 4M1KA 4JI8E 3J80C 3P3EA 4GKJI 3GLLA 5ELWA 4LF7I 1YH8A 4DR5E 1UEKA 1PVGA 1Z5BA 2OI2A 2LJPA 2NN6A 4QNKA 2HKJA 1ZM9A 2NN6F 2PO0B 1WUUA 3PS3A 1D6TA 1OYRA 4MU3A 4LFCI 2X7IA 3L7ZB 3CDJA 1A6FA 4P52A 5LMNE 1FWLA 4JI0E 4MQYA 2BV3A 2XEXA 5IT9Q 1Z59A 2C39A 2A2DA 4HY1A 4URLA 4JI7I 2BM0A 4JI4I 1NHIA 1Z0VA 2JE6A 2UUAE 1S16A 4IZKB 1PIEA 4Z7YA 5BR8E 2UUBE 1RHYA 2C38B 1UDNA 5K36A 2WNRB 1XHKA 2ZM6E 1UDQA 4DV3I 2R3VA 5C0XD 1J5EI 2IOQA 1UDSA 1NHJA 4B3SI 5A2QQ 3M7ND 4ISAA 2VESA 5L3JA 5GMDA 4MYTA 1FJGI 3V2UC 4OX9E 1KTVA 3P76A 3UHMA 3J80Q 3M85G 5K36B 4DUYE 1XNRI 4LPFA 4B3RE 2Z5BA 2ZBKB 3T1YE 4OO1E 4LFBI 1EI1A 5DRQA 1HK7A 3T1HE 4DV6E 2UU9E 1OYPA 2DEJA 3QT7A 1N36I 4JI3E 4LF4E 2VQEI 4LF8I 5DRPA 4LCFA 4FW6A 1FI4A 1P42A 1Y5YA 2Z5EA 3U1YA 5JEAA 5LL6R 4GQUA 4DPYA 4FN5A 1XXEA 2HFUA 1HR0I 3H1CA 4DV0E 4JYAI 1USUA 2CZ9A 2JEBA 2UXCI 3J7AM 2IOPA 2UXBI 5C0XE 3HKMA 4LF5E 4U3BA 4DR4E 1IBLI 3P3GA 2UXDI 1Z0BA 4DPXA 4MYUA 4DU8A 3LTOA 4DV2E 4B3TI 4OO1F 4OO1A 1MU5A 4J3DA 4HXZA 1K47A 5JEAF 3K17A 4X62E 4IFDC 3LNUA 4HACB 4WUDA 4PRXA 4PU9A 5JEAE 3CDIA 5JEAD 1HNXI 2GO3A 4JI5I 1RREA 5C0XF 2UUCE 4X65E 4YY3I 2F4VE 2PNMA 3QT5A 4DR2E 4DR3E 4GKKI 4JI8I 3Q1QA 1XMOI 3WU6A 1IBKI 2Z5CA 5FWKA 4DV1E 1QZRA 4EMDA 2GS8A 2O3ZA 2F1DA 2BR2A 3J7AG 5A2QC 3ZZUA 5JEAB 3M85D 1HNZE 4YHHI 1FWKA 4ZVIA 5IWAE 3CWVA 1VI7A 4JI0I 2PO2A 4FW9A 4N3OA 3B4TA 1Y4UA 1NHHA 1N0UA 5LMUE 4JI7E 4K0KI 1H73A 1HNWE 5DROA 2JEAA 4KHPE 3GMEA 1N33I 2UUAI 5DRRA 1XNQI 3WU5A 3D4JA 2BA1D 4JG4A 1OJ4A 2JT2A 4DV5I 4IFDB 4X64I 2AE8A 4JV5I 1BKNA 1VISA 1Z0TA 1MX0A 4JI6I 4B3MI 3OTOI 4FWGA 3J81Q 3T1YI 2EFGA 1ZXNA 4LCGA 1XMQI 1YHCA 1ZXMA 2E5LI 4DV6I 4JI1E 3PYFA 5DNLA 1S4EA 2UU9I 4DR7I 5K36E 3U1KA 5K36C 5K36F 4OO1B 4NXNE 4LF4I 1U2RA 4LFAI 4HYMA 2IESA 2BA0D 1USVA 1E3PA 2VQFI 3PYGA 1N32I 3L7ZA 4R1FA 1UDOA 1Z5AA 4IZJB 2V34A 4LFCE 1Y4SA 1DARA 4DV4E 2JEBB 2J65A 4BA2B 1HR0E 4DV0I 1H74A 4DR6E 1R6MA 2UXCE 4LF9E 4LF6E 5BR8I 1I94I 5C0XC 4IZJD 4FW5A 4X66I 1ZM3A 2DEIA 4IZJA 2HHHE 5C0XA 2O1UA 3GCMA 1IBME 2ZITA 4DPWA 1KKHA 4DR5I 5JEAC 1FJGE 2V8PA 4QNJA 3NZKA 2PO1A 4IFDF 3WU4A 4AQYE 1OYSA 3PRYA 1N34E 1XNRE 2NN6C 3ZKBA 1EA6A 4LFBE 4FWDA 4YY3E 2F4VI 4I3HA 3T1HI 1XMOE 1IBKE 4DV1I 4XTJA 3GONA 4FWHA 1N36E 4JI4E 5EL9A 4JI3I 2VQEE 1HNZI 3Q6NA 4YHHE 2A2CA 3DD6A 2NN6D 3PYEA 1ZM4A 1RR9A 4OZEA 2NN6E 2O1WA 2R42A 4DV3E 2Q2EB 4OO1D 4MDTA 3ZZTA 4B3SE 3P06A 3JAMC 4DR1E 2JEAB 2CG9A 4DV7E 1MG7A 3V5RA 4K0KE 5EKWA 5C0XB 4KHPI 4MU1A 1Z5CA 1N33E 3PS2A 4DUYI 4LOMA 2UXBE 3H4LA 2PO0A 1IBLE 4NXME 3QT8A 5GMEA 4OO1C 4DV2I 4B3TE 4DUZE 4JI2I 5K36D 4BA1A 2BR2B 1Z0CA 3JAMQ 4FW4A 3K1JA 4WUBA 3ZKDA 4GKJE 2AJ4A 5DNXA 4RPFA 1Y60A 2PNZB 4LF7E 4B3ME 2WP8A 3OTOE 4AIDA 3P3CA 2J7KA 1HNXE 2C37A 4JI5E 1ELOA 4X65I 2WNRA 2NPFA 5LMNI 3PS1A 5IT9C 4HACA 3B82A 1Z0EA 4JYAE 1Y6ZA 4NXNI 2HKEA 2WW4A 3Q6MA 3LPSA 3B8HA 1R6LA 2C39B 4U3DA 3HJCA 4ED4A 2VQFE 4OKGA 1B63A 1N32E 1FNMA 2HK3A 4AM3A 2UUBI 2GO4A 2X36A 2UXDE 4DXLA 2C37B 2ZM6I 1J5EE 4DPTA 4UT4A 2BA0G 3K85A 2NN6B 3ZM7A 4OX9I 2WP8B 4USKA 5LMUI 1HNWI 2PNZA 4AIMA 4IFDA 4BA1B 4Z7CA 3PYDA 4IFDD 4MU4A 3HULA 2IERA 4MU0A 4LF6I 4B3RI 4USMA 4BA2A 2VF3A 4X66E 2UUCI 2HHHI 3J81C 1Z0GA 4GKKE 1IBMI 4X64E 4PRVA 3M7NG 4JV5E 4DPUA 2PO2B 4AQYI 2GQ0A 2V2QA 1ZM2A 1KIJA 4LF8E 1N34I 1FKAE 2BA1G 4KQVA 1KVKA 5IWAI 2Z5BB 2O1TA 2O1VA 2E5LE 4P7AA 5FLXC 1E3HA 2V2ZA 4DR7E 4FW7A 3WU3A 2Z5CB 1H7SA 3M6AA 1B62A 4LFAE
chains in the Genus database with same CATH topology
5DRPA 3P76A 4LCFA 4FW6A 5DROA 3UHMA 2J65A 3NZKA 4FW3A 1P42A 4LCGA 2O3ZA 1YHCA 3PS1A 4J3DA 3P3EA 5DRRA 3U1YA 1YH8A 1XXEA 2IERA 4OZEA 5DRQA 4FW4A 2JT2A 4MDTA 4U3DA 4OKGA 4FW7A 3PS3A 3P3CA 2GO3A 2IESA 2GO4A 4FW5A 4IS9A 4ISAA 2VESA 4LCHA 4U3BA 3PS2A 3P3GA 4MQYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DRP A;  3P76 A;  4LCF A;  4FW6 A;  5DRO A;  3UHM A;  2J65 A;  3NZK A;  4FW3 A;  1P42 A;  4LCG A;  2O3Z A;  1YHC A;  3PS1 A;  4J3D A;  3P3E A;  5DRR A;  3U1Y A;  1YH8 A;  1XXE A;  2IER A;  4OZE A;  5DRQ A;  4FW4 A;  2JT2 A;  4MDT A;  4U3D A;  4OKG A;  4FW7 A;  3PS3 A;  3P3C A;  2GO3 A;  2IES A;  2GO4 A;  4FW5 A;  4IS9 A;  4ISA A;  2VES A;  4LCH A;  4U3B A;  3PS2 A;  3P3G A;  4MQY A; 
#chains in the Genus database with same CATH topology
 1XNQ E;  4NBQ A;  2CVE A;  3F0N A;  4LF5 I;  2E1R A;  3QT6 A;  4DR4 I;  1PKP A;  1H72 C;  4DV5 E;  1N0V C;  4IZK A;  2C38 A;  4DV4 I;  2JE6 B;  4DR1 I;  1H7U A;  4WUC A;  5FLX Q;  4DV7 I;  4IFD E;  2CGE A;  2PNL A;  4JI6 E;  4X62 I;  2HFS A;  4DR6 I;  2PO1 B;  1Z0W A;  3KRN A;  4LF9 I;  2HK2 A;  4DU7 A;  4IS9 A;  1NZ0 A;  3B78 A;  4LCH A;  1I94 E;  1XMQ E;  2V2V A;  4NXM I;  2BM1 A;  3ZZ0 A;  4DUZ I;  4JI2 E;  4JI1 I;  4DR2 I;  4UTG A;  4DR3 I;  4FW3 A;  4M1K A;  4JI8 E;  3J80 C;  3P3E A;  4GKJ I;  3GLL A;  5ELW A;  4LF7 I;  1YH8 A;  4DR5 E;  1UEK A;  1PVG A;  1Z5B A;  2OI2 A;  2LJP A;  2NN6 A;  4QNK A;  2HKJ A;  1ZM9 A;  2NN6 F;  2PO0 B;  1WUU A;  3PS3 A;  1D6T A;  1OYR A;  4MU3 A;  4LFC I;  2X7I A;  3L7Z B;  3CDJ A;  1A6F A;  4P52 A;  5LMN E;  1FWL A;  4JI0 E;  4MQY A;  2BV3 A;  2XEX A;  5IT9 Q;  1Z59 A;  2C39 A;  2A2D A;  4HY1 A;  4URL A;  4JI7 I;  2BM0 A;  4JI4 I;  1NHI A;  1Z0V A;  2JE6 A;  2UUA E;  1S16 A;  4IZK B;  1PIE A;  4Z7Y A;  5BR8 E;  2UUB E;  1RHY A;  2C38 B;  1UDN A;  5K36 A;  2WNR B;  1XHK A;  2ZM6 E;  1UDQ A;  4DV3 I;  2R3V A;  5C0X D;  1J5E I;  2IOQ A;  1UDS A;  1NHJ A;  4B3S I;  5A2Q Q;  3M7N D;  4ISA A;  2VES A;  5L3J A;  5GMD A;  4MYT A;  1FJG I;  3V2U C;  4OX9 E;  1KTV A;  3P76 A;  3UHM A;  3J80 Q;  3M85 G;  5K36 B;  4DUY E;  1XNR I;  4LPF A;  4B3R E;  2Z5B A;  2ZBK B;  3T1Y E;  4OO1 E;  4LFB I;  1EI1 A;  5DRQ A;  1HK7 A;  3T1H E;  4DV6 E;  2UU9 E;  1OYP A;  2DEJ A;  3QT7 A;  1N36 I;  4JI3 E;  4LF4 E;  2VQE I;  4LF8 I;  5DRP A;  4LCF A;  4FW6 A;  1FI4 A;  1P42 A;  1Y5Y A;  2Z5E A;  3U1Y A;  5JEA A;  5LL6 R;  4GQU A;  4DPY A;  4FN5 A;  1XXE A;  2HFU A;  1HR0 I;  3H1C A;  4DV0 E;  4JYA I;  1USU A;  2CZ9 A;  2JEB A;  2UXC I;  3J7A M;  2IOP A;  2UXB I;  5C0X E;  3HKM A;  4LF5 E;  4U3B A;  4DR4 E;  1IBL I;  3P3G A;  2UXD I;  1Z0B A;  4DPX A;  4MYU A;  4DU8 A;  3LTO A;  4DV2 E;  4B3T I;  4OO1 F;  4OO1 A;  1MU5 A;  4J3D A;  4HXZ A;  1K47 A;  5JEA F;  3K17 A;  4X62 E;  4IFD C;  3LNU A;  4HAC B;  4WUD A;  4PRX A;  4PU9 A;  5JEA E;  3CDI A;  5JEA D;  1HNX I;  2GO3 A;  4JI5 I;  1RRE A;  5C0X F;  2UUC E;  4X65 E;  4YY3 I;  2F4V E;  2PNM A;  3QT5 A;  4DR2 E;  4DR3 E;  4GKK I;  4JI8 I;  3Q1Q A;  1XMO I;  3WU6 A;  1IBK I;  2Z5C A;  5FWK A;  4DV1 E;  1QZR A;  4EMD A;  2GS8 A;  2O3Z A;  2F1D A;  2BR2 A;  3J7A G;  5A2Q C;  3ZZU A;  5JEA B;  3M85 D;  1HNZ E;  4YHH I;  1FWK A;  4ZVI A;  5IWA E;  3CWV A;  1VI7 A;  4JI0 I;  2PO2 A;  4FW9 A;  4N3O A;  3B4T A;  1Y4U A;  1NHH A;  1N0U A;  5LMU E;  4JI7 E;  4K0K I;  1H73 A;  1HNW E;  5DRO A;  2JEA A;  4KHP E;  3GME A;  1N33 I;  2UUA I;  5DRR A;  1XNQ I;  3WU5 A;  3D4J A;  2BA1 D;  4JG4 A;  1OJ4 A;  2JT2 A;  4DV5 I;  4IFD B;  4X64 I;  2AE8 A;  4JV5 I;  1BKN A;  1VIS A;  1Z0T A;  1MX0 A;  4JI6 I;  4B3M I;  3OTO I;  4FWG A;  3J81 Q;  3T1Y I;  2EFG A;  1ZXN A;  4LCG A;  1XMQ I;  1YHC A;  1ZXM A;  2E5L I;  4DV6 I;  4JI1 E;  3PYF A;  5DNL A;  1S4E A;  2UU9 I;  4DR7 I;  5K36 E;  3U1K A;  5K36 C;  5K36 F;  4OO1 B;  4NXN E;  4LF4 I;  1U2R A;  4LFA I;  4HYM A;  2IES A;  2BA0 D;  1USV A;  1E3P A;  2VQF I;  3PYG A;  1N32 I;  3L7Z A;  4R1F A;  1UDO A;  1Z5A A;  4IZJ B;  2V34 A;  4LFC E;  1Y4S A;  1DAR A;  4DV4 E;  2JEB B;  2J65 A;  4BA2 B;  1HR0 E;  4DV0 I;  1H74 A;  4DR6 E;  1R6M A;  2UXC E;  4LF9 E;  4LF6 E;  5BR8 I;  1I94 I;  5C0X C;  4IZJ D;  4FW5 A;  4X66 I;  1ZM3 A;  2DEI A;  4IZJ A;  2HHH E;  5C0X A;  2O1U A;  3GCM A;  1IBM E;  2ZIT A;  4DPW A;  1KKH A;  4DR5 I;  5JEA C;  1FJG E;  2V8P A;  4QNJ A;  3NZK A;  2PO1 A;  4IFD F;  3WU4 A;  4AQY E;  1OYS A;  3PRY A;  1N34 E;  1XNR E;  2NN6 C;  3ZKB A;  1EA6 A;  4LFB E;  4FWD A;  4YY3 E;  2F4V I;  4I3H A;  3T1H I;  1XMO E;  1IBK E;  4DV1 I;  4XTJ A;  3GON A;  4FWH A;  1N36 E;  4JI4 E;  5EL9 A;  4JI3 I;  2VQE E;  1HNZ I;  3Q6N A;  4YHH E;  2A2C A;  3DD6 A;  2NN6 D;  3PYE A;  1ZM4 A;  1RR9 A;  4OZE A;  2NN6 E;  2O1W A;  2R42 A;  4DV3 E;  2Q2E B;  4OO1 D;  4MDT A;  3ZZT A;  4B3S E;  3P06 A;  3JAM C;  4DR1 E;  2JEA B;  2CG9 A;  4DV7 E;  1MG7 A;  3V5R A;  4K0K E;  5EKW A;  5C0X B;  4KHP I;  4MU1 A;  1Z5C A;  1N33 E;  3PS2 A;  4DUY I;  4LOM A;  2UXB E;  3H4L A;  2PO0 A;  1IBL E;  4NXM E;  3QT8 A;  5GME A;  4OO1 C;  4DV2 I;  4B3T E;  4DUZ E;  4JI2 I;  5K36 D;  4BA1 A;  2BR2 B;  1Z0C A;  3JAM Q;  4FW4 A;  3K1J A;  4WUB A;  3ZKD A;  4GKJ E;  2AJ4 A;  5DNX A;  4RPF A;  1Y60 A;  2PNZ B;  4LF7 E;  4B3M E;  2WP8 A;  3OTO E;  4AID A;  3P3C A;  2J7K A;  1HNX E;  2C37 A;  4JI5 E;  1ELO A;  4X65 I;  2WNR A;  2NPF A;  5LMN I;  3PS1 A;  5IT9 C;  4HAC A;  3B82 A;  1Z0E A;  4JYA E;  1Y6Z A;  4NXN I;  2HKE A;  2WW4 A;  3Q6M A;  3LPS A;  3B8H A;  1R6L A;  2C39 B;  4U3D A;  3HJC A;  4ED4 A;  2VQF E;  4OKG A;  1B63 A;  1N32 E;  1FNM A;  2HK3 A;  4AM3 A;  2UUB I;  2GO4 A;  2X36 A;  2UXD E;  4DXL A;  2C37 B;  2ZM6 I;  1J5E E;  4DPT A;  4UT4 A;  2BA0 G;  3K85 A;  2NN6 B;  3ZM7 A;  4OX9 I;  2WP8 B;  4USK A;  5LMU I;  1HNW I;  2PNZ A;  4AIM A;  4IFD A;  4BA1 B;  4Z7C A;  3PYD A;  4IFD D;  4MU4 A;  3HUL A;  2IER A;  4MU0 A;  4LF6 I;  4B3R I;  4USM A;  4BA2 A;  2VF3 A;  4X66 E;  2UUC I;  2HHH I;  3J81 C;  1Z0G A;  4GKK E;  1IBM I;  4X64 E;  4PRV A;  3M7N G;  4JV5 E;  4DPU A;  2PO2 B;  4AQY I;  2GQ0 A;  2V2Q A;  1ZM2 A;  1KIJ A;  4LF8 E;  1N34 I;  1FKA E;  2BA1 G;  4KQV A;  1KVK A;  5IWA I;  2Z5B B;  2O1T A;  2O1V A;  2E5L E;  4P7A A;  5FLX C;  1E3H A;  2V2Z A;  4DR7 E;  4FW7 A;  3WU3 A;  2Z5C B;  1H7S A;  3M6A A;  1B62 A;  4LFA E; 
#chains in the Genus database with same CATH homology
 5DRP A;  3P76 A;  4LCF A;  4FW6 A;  5DRO A;  3UHM A;  2J65 A;  3NZK A;  4FW3 A;  1P42 A;  4LCG A;  2O3Z A;  1YHC A;  3PS1 A;  4J3D A;  3P3E A;  5DRR A;  3U1Y A;  1YH8 A;  1XXE A;  2IER A;  4OZE A;  5DRQ A;  4FW4 A;  2JT2 A;  4MDT A;  4U3D A;  4OKG A;  4FW7 A;  3PS3 A;  3P3C A;  2GO3 A;  2IES A;  2GO4 A;  4FW5 A;  4IS9 A;  4ISA A;  2VES A;  4LCH A;  4U3B A;  3PS2 A;  3P3G A;  4MQY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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