2GO3A

Crystal structure of aquifex aeolicus lpxc complexed with imidazole.
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
266
structure length
266
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Mechanistic Inferences from the Binding of Ligands to LpxC, a Metal-Dependent Deacetylase
pubmed doi rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
total genus 91
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2006-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 2go3A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 2go3A02
2GO3A 4J3DA 3P3CA 4FW5A 4FW3A 5DRQA 5DRRA 3PS3A 1XXEA 4FW6A 3P76A 1YH8A 4LCFA 4ISAA 3P3EA 4FW4A 3P3GA 4U3BA 3PS1A 2O3ZA 4LCHA 2IESA 5DROA 5DRPA 1P42A 4MQYA 3UHMA 4OZEA 4LCGA 2JT2A 3PS2A 3NZKA 2IERA 4OKGA 2J65A 3U1YA 1YHCA 2GO4A 4MDTA 4U3DA 2VESA 4FW7A 4IS9A
chains in the Genus database with same CATH superfamily
2JEBB 1Y4SA 3PYFA 4DV7I 4OX9E 5DRRA 2E5LE 2UUAE 1Y4UA 1YH8A 4LOMA 2OI2A 4GKKE 3T1YE 2BV3A 3PS1A 4X66E 4DR2E 3ZKDA 1ZM9A 4XTJA 4LF9I 1MG7A 2JE6B 4JI7E 4NXME 4DUZI 5A2QQ 4JI3I 3LTOA 4JI6I 3J81Q 4JI1E 5K36D 1I94E 3CDJA 2C38A 4IZKB 4IZJD 1J5EE 1XNQE 2C37A 2C39B 2V2VA 1ZXNA 5EKWA 1IBKE 4DUYE 1XXEA 2PNZB 4HYMA 4LCFA 2UXDI 4UTGA 1OJ4A 4WUCA 2BA0G 2ZBKB 1UDQA 1H7SA 4AQYI 2Q2EB 2A2CA 4FN5A 1XMQI 4DPXA 1VI7A 4LFAI 1HNXE 2UUCE 3V5RA 3U1YA 1R6LA 4HACA 2V8PA 2PO2B 5ELWA 4B3TE 4KQVA 2CZ9A 4DU8A 3QT5A 2V2ZA 4DR7I 4PU9A 1HK7A 1H72C 4DR4I 1A6FA 1FWLA 2VQFI 1HNZI 5DNXA 3GCMA 2PNLA 1FJGI 5IWAE 4AIMA 3CWVA 3P3GA 2NPFA 3T1HI 1BKNA 5C0XB 1DARA 3M85D 2IOPA 4DV2E 5C0XE 2NN6F 3KRNA 2DEJA 3DD6A 3JAMQ 4NXNI 4LF4E 2UUBE 4LF6I 4K0KE 5LL6R 3J80C 2CVEA 4OO1D 4RPFA 1Y60A 1USUA 1Z0BA 2UXBI 5JEAA 2GQ0A 4N3OA 3M85G 4FW4A 1IBLE 2O3ZA 4JI0I 1N32I 4DR1I 3QT7A 1PKPA 1D6TA 4YY3I 2NN6A 1UEKA 3M6AA 4DU7A 4WUBA 4JYAE 4DPUA 1NHHA 4LF8E 2JEBA 2R3VA 3J7AM 4X62E 4U3DA 1HNWE 4MU0A 4DV5E 4FW7A 4EMDA 3OTOI 1Z0CA 3PYGA 5K36F 3PYEA 1FKAE 4FW5A 1N36I 3CDIA 2O1TA 5JEAC 4DV1I 2UXCE 4JI4E 4USMA 2JE6A 1Z0WA 3B82A 3PYDA 1USVA 2X7IA 5JEAE 2GS8A 2JT2A 2UU9E 1H73A 3Q1QA 2WNRB 4OKGA 4DPTA 5FLXQ 2C39A 2V2QA 2NN6C 5LMUI 4LF9E 1H74A 2ZM6I 3K1JA 2AJ4A 3ZZUA 3Q6NA 4DUZE 4JI3E 1XNRE 4AIDA 1IBMI 2PNZA 4JI6E 4BA2B 2EFGA 1RHYA 2HKEA 2NN6E 4FW9A 4B3SE 4DV0I 4WUDA 1ELOA 2PNMA 1N0UA 1OYRA 1KIJA 1N34I 2DEIA 2HK2A 1XMOE 2X36A 2BA0D 2UXDE 3F0NA 2PO2A 4AQYE 1XMQE 4JV5E 4LFAE 4J3DA 3GMEA 1FI4A 1UDOA 4JI5E 5C0XA 4HY1A 3ZZTA 4GQUA 2IOQA 4OO1F 4IFDD 4HXZA 1K47A 1UDNA 4DV4I 5K36B 4DR4E 1H7UA 2VQFE 4LCGA 4IZJB 5LMNI 2WP8B 1HNZE 4LF5I 2O1WA 1FJGE 4DR6I 4KHPI 3T1HE 2VQEI 1Z5BA 4DV6E 1N33I 3K85A 4GKKI 4PRVA 5DROA 2BR2B 4LF7E 3T1YI 4IFDB 4NBQA 3P3CA 5C0XC 3GONA 3K17A 5BR8E 4B3RE 4NXNE 4X65I 1B62A 4LF6E 1ZM4A 4FWHA 4PRXA 2UXBE 1J5EI 1XNQI 1KKHA 3D4JA 1Y5YA 3WU6A 5DNLA 1E3PA 4JI0E 1N32E 2JEAB 4DR1E 2HFUA 2F4VI 1FNMA 1KTVA 4X64E 3H4LA 5DRQA 3WU4A 3WU3A 1N0VC 1HR0I 3WU5A 3J80Q 2HHHI 3OTOE 4DV3I 2UUCI 1N36E 4B3ME 5DRPA 2WNRA 4DV1E 2Z5BB 3P06A 4JI2I 2CGEA 3NZKA 1WUUA 2F1DA 4OO1B 5IT9Q 4BA2A 2O1UA 4URLA 2BM0A 4JG4A 2R42A 3B78A 2ZM6E 2HK3A 4DV2I 2Z5EA 2PO0B 1IBME 4LFBE 3P3EA 2BA1D 4DV7E 4QNKA 4LFCI 3UHMA 4OZEA 5JEAD 4IFDF 2ZITA 4IZKA 1N34E 2J65A 4P52A 3PRYA 3LNUA 4DR3I 4FW3A 2BA1G 3PS3A 4JI8I 5K36A 2NN6D 2BM1A 1ZXMA 2V34A 4IZJA 2WP8A 4JYAI 4U3BA 3QT6A 5FLXC 1NZ0A 1OYSA 2CG9A 4DXLA 5C0XF 1FWKA 1Z5AA 4UT4A 2WW4A 1U2RA 2IERA 1NHJA 2BR2A 1Z59A 4IFDA 1MU5A 3ZM7A 5LMNE 4MDTA 4LF5E 1EA6A 4DR6E 1RREA 4GKJI 4IS9A 2VQEE 2GO3A 2A2DA 1N33E 4DR5I 3B4TA 3GLLA 2UU9I 5K36C 2LJPA 3L7ZB 1ZM3A 5A2QC 4QNJA 4BA1B 2PO1B 4DR7E 4LCHA 2IESA 3J81C 4YHHI 3V2UC 2HKJA 1XNRI 3LPSA 1RR9A 4X65E 2JEAA 4P7AA 5K36E 4Z7CA 4OX9I 4IFDC 4B3SI 4M1KA 3ZKBA 2E5LI 2UUAI 2GO4A 2Z5CB 2VESA 1UDSA 1ZM2A 4X66I 4AM3A 4DR2I 1XMOI 4JI7I 2F4VE 4NXMI 4IFDE 4FWDA 2Z5BA 4FWGA 4MU3A 1XHKA 4MYUA 4JI1I 1NHIA 1Z5CA 1I94I 4OO1A 4JV5I 1S16A 1HR0E 2HHHE 3PS2A 4DV3E 3HJCA 5C0XD 1IBKI 4USKA 1E3HA 4DUYI 1R6MA 4JI5I 1YHCA 4MU1A 4DPWA 4JI2E 5JEAF 2PO0A 4YY3E 2C38B 4I3HA 2J7KA 2C37B 4FW6A 3P76A 1Z0TA 1EI1A 2AE8A 4MYTA 4DV6I 1HNXI 3M7ND 4OO1C 4B3TI 4LF7I 3JAMC 3QT8A 1PIEA 4LFCE 5L3JA 1KVKA 1VISA 5BR8I 4B3RI 4OO1E 4HACB 5IWAI 3J7AG 5LMUE 4MU4A 2VF3A 3U1KA 4ISAA 4DR3E 3M7NG 3Q6MA 2O1VA 1P42A 5IT9C 4JI8E 1B63A 4DV0E 3H1CA 4X64I 4LF4I 2UUBI 4K0KI 3B8HA 4ZVIA 1Y6ZA 1QZRA 1MX0A 4DPYA 4B3MI 5GMDA 1S4EA 3L7ZA 1IBLI 2E1RA 4BA1A 5FWKA 2PO1A 1PVGA 1Z0GA 4GKJE 5JEAB 2XEXA 4DR5E 4LF8I 4Z7YA 4MQYA 4R1FA 4X62I 1HNWI 4DV5I 2HFSA 2Z5CA 5EL9A 1Z0EA 3HULA 3HKMA 4YHHE 4DV4E 3ZZ0A 4ED4A 2UXCI 4LFBI 4JI4I 5GMEA 1Z0VA 2NN6B 1OYPA 4KHPE 4LPFA
chains in the Genus database with same CATH topology
2GO3A 4J3DA 3P3CA 4FW5A 4FW3A 5DRQA 5DRRA 3PS3A 1XXEA 4FW6A 3P76A 1YH8A 4LCFA 4ISAA 3P3EA 4FW4A 3P3GA 4U3BA 3PS1A 2O3ZA 4LCHA 2IESA 5DROA 5DRPA 1P42A 4MQYA 3UHMA 4OZEA 4LCGA 2JT2A 3PS2A 3NZKA 2IERA 4OKGA 2J65A 3U1YA 1YHCA 2GO4A 4MDTA 4U3DA 2VESA 4FW7A 4IS9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GO3 A;  4J3D A;  3P3C A;  4FW5 A;  4FW3 A;  5DRQ A;  5DRR A;  3PS3 A;  1XXE A;  4FW6 A;  3P76 A;  1YH8 A;  4LCF A;  4ISA A;  3P3E A;  4FW4 A;  3P3G A;  4U3B A;  3PS1 A;  2O3Z A;  4LCH A;  2IES A;  5DRO A;  5DRP A;  1P42 A;  4MQY A;  3UHM A;  4OZE A;  4LCG A;  2JT2 A;  3PS2 A;  3NZK A;  2IER A;  4OKG A;  2J65 A;  3U1Y A;  1YHC A;  2GO4 A;  4MDT A;  4U3D A;  2VES A;  4FW7 A;  4IS9 A; 
#chains in the Genus database with same CATH topology
 2JEB B;  1Y4S A;  3PYF A;  4DV7 I;  4OX9 E;  5DRR A;  2E5L E;  2UUA E;  1Y4U A;  1YH8 A;  4LOM A;  2OI2 A;  4GKK E;  3T1Y E;  2BV3 A;  3PS1 A;  4X66 E;  4DR2 E;  3ZKD A;  1ZM9 A;  4XTJ A;  4LF9 I;  1MG7 A;  2JE6 B;  4JI7 E;  4NXM E;  4DUZ I;  5A2Q Q;  4JI3 I;  3LTO A;  4JI6 I;  3J81 Q;  4JI1 E;  5K36 D;  1I94 E;  3CDJ A;  2C38 A;  4IZK B;  4IZJ D;  1J5E E;  1XNQ E;  2C37 A;  2C39 B;  2V2V A;  1ZXN A;  5EKW A;  1IBK E;  4DUY E;  1XXE A;  2PNZ B;  4HYM A;  4LCF A;  2UXD I;  4UTG A;  1OJ4 A;  4WUC A;  2BA0 G;  2ZBK B;  1UDQ A;  1H7S A;  4AQY I;  2Q2E B;  2A2C A;  4FN5 A;  1XMQ I;  4DPX A;  1VI7 A;  4LFA I;  1HNX E;  2UUC E;  3V5R A;  3U1Y A;  1R6L A;  4HAC A;  2V8P A;  2PO2 B;  5ELW A;  4B3T E;  4KQV A;  2CZ9 A;  4DU8 A;  3QT5 A;  2V2Z A;  4DR7 I;  4PU9 A;  1HK7 A;  1H72 C;  4DR4 I;  1A6F A;  1FWL A;  2VQF I;  1HNZ I;  5DNX A;  3GCM A;  2PNL A;  1FJG I;  5IWA E;  4AIM A;  3CWV A;  3P3G A;  2NPF A;  3T1H I;  1BKN A;  5C0X B;  1DAR A;  3M85 D;  2IOP A;  4DV2 E;  5C0X E;  2NN6 F;  3KRN A;  2DEJ A;  3DD6 A;  3JAM Q;  4NXN I;  4LF4 E;  2UUB E;  4LF6 I;  4K0K E;  5LL6 R;  3J80 C;  2CVE A;  4OO1 D;  4RPF A;  1Y60 A;  1USU A;  1Z0B A;  2UXB I;  5JEA A;  2GQ0 A;  4N3O A;  3M85 G;  4FW4 A;  1IBL E;  2O3Z A;  4JI0 I;  1N32 I;  4DR1 I;  3QT7 A;  1PKP A;  1D6T A;  4YY3 I;  2NN6 A;  1UEK A;  3M6A A;  4DU7 A;  4WUB A;  4JYA E;  4DPU A;  1NHH A;  4LF8 E;  2JEB A;  2R3V A;  3J7A M;  4X62 E;  4U3D A;  1HNW E;  4MU0 A;  4DV5 E;  4FW7 A;  4EMD A;  3OTO I;  1Z0C A;  3PYG A;  5K36 F;  3PYE A;  1FKA E;  4FW5 A;  1N36 I;  3CDI A;  2O1T A;  5JEA C;  4DV1 I;  2UXC E;  4JI4 E;  4USM A;  2JE6 A;  1Z0W A;  3B82 A;  3PYD A;  1USV A;  2X7I A;  5JEA E;  2GS8 A;  2JT2 A;  2UU9 E;  1H73 A;  3Q1Q A;  2WNR B;  4OKG A;  4DPT A;  5FLX Q;  2C39 A;  2V2Q A;  2NN6 C;  5LMU I;  4LF9 E;  1H74 A;  2ZM6 I;  3K1J A;  2AJ4 A;  3ZZU A;  3Q6N A;  4DUZ E;  4JI3 E;  1XNR E;  4AID A;  1IBM I;  2PNZ A;  4JI6 E;  4BA2 B;  2EFG A;  1RHY A;  2HKE A;  2NN6 E;  4FW9 A;  4B3S E;  4DV0 I;  4WUD A;  1ELO A;  2PNM A;  1N0U A;  1OYR A;  1KIJ A;  1N34 I;  2DEI A;  2HK2 A;  1XMO E;  2X36 A;  2BA0 D;  2UXD E;  3F0N A;  2PO2 A;  4AQY E;  1XMQ E;  4JV5 E;  4LFA E;  4J3D A;  3GME A;  1FI4 A;  1UDO A;  4JI5 E;  5C0X A;  4HY1 A;  3ZZT A;  4GQU A;  2IOQ A;  4OO1 F;  4IFD D;  4HXZ A;  1K47 A;  1UDN A;  4DV4 I;  5K36 B;  4DR4 E;  1H7U A;  2VQF E;  4LCG A;  4IZJ B;  5LMN I;  2WP8 B;  1HNZ E;  4LF5 I;  2O1W A;  1FJG E;  4DR6 I;  4KHP I;  3T1H E;  2VQE I;  1Z5B A;  4DV6 E;  1N33 I;  3K85 A;  4GKK I;  4PRV A;  5DRO A;  2BR2 B;  4LF7 E;  3T1Y I;  4IFD B;  4NBQ A;  3P3C A;  5C0X C;  3GON A;  3K17 A;  5BR8 E;  4B3R E;  4NXN E;  4X65 I;  1B62 A;  4LF6 E;  1ZM4 A;  4FWH A;  4PRX A;  2UXB E;  1J5E I;  1XNQ I;  1KKH A;  3D4J A;  1Y5Y A;  3WU6 A;  5DNL A;  1E3P A;  4JI0 E;  1N32 E;  2JEA B;  4DR1 E;  2HFU A;  2F4V I;  1FNM A;  1KTV A;  4X64 E;  3H4L A;  5DRQ A;  3WU4 A;  3WU3 A;  1N0V C;  1HR0 I;  3WU5 A;  3J80 Q;  2HHH I;  3OTO E;  4DV3 I;  2UUC I;  1N36 E;  4B3M E;  5DRP A;  2WNR A;  4DV1 E;  2Z5B B;  3P06 A;  4JI2 I;  2CGE A;  3NZK A;  1WUU A;  2F1D A;  4OO1 B;  5IT9 Q;  4BA2 A;  2O1U A;  4URL A;  2BM0 A;  4JG4 A;  2R42 A;  3B78 A;  2ZM6 E;  2HK3 A;  4DV2 I;  2Z5E A;  2PO0 B;  1IBM E;  4LFB E;  3P3E A;  2BA1 D;  4DV7 E;  4QNK A;  4LFC I;  3UHM A;  4OZE A;  5JEA D;  4IFD F;  2ZIT A;  4IZK A;  1N34 E;  2J65 A;  4P52 A;  3PRY A;  3LNU A;  4DR3 I;  4FW3 A;  2BA1 G;  3PS3 A;  4JI8 I;  5K36 A;  2NN6 D;  2BM1 A;  1ZXM A;  2V34 A;  4IZJ A;  2WP8 A;  4JYA I;  4U3B A;  3QT6 A;  5FLX C;  1NZ0 A;  1OYS A;  2CG9 A;  4DXL A;  5C0X F;  1FWK A;  1Z5A A;  4UT4 A;  2WW4 A;  1U2R A;  2IER A;  1NHJ A;  2BR2 A;  1Z59 A;  4IFD A;  1MU5 A;  3ZM7 A;  5LMN E;  4MDT A;  4LF5 E;  1EA6 A;  4DR6 E;  1RRE A;  4GKJ I;  4IS9 A;  2VQE E;  2GO3 A;  2A2D A;  1N33 E;  4DR5 I;  3B4T A;  3GLL A;  2UU9 I;  5K36 C;  2LJP A;  3L7Z B;  1ZM3 A;  5A2Q C;  4QNJ A;  4BA1 B;  2PO1 B;  4DR7 E;  4LCH A;  2IES A;  3J81 C;  4YHH I;  3V2U C;  2HKJ A;  1XNR I;  3LPS A;  1RR9 A;  4X65 E;  2JEA A;  4P7A A;  5K36 E;  4Z7C A;  4OX9 I;  4IFD C;  4B3S I;  4M1K A;  3ZKB A;  2E5L I;  2UUA I;  2GO4 A;  2Z5C B;  2VES A;  1UDS A;  1ZM2 A;  4X66 I;  4AM3 A;  4DR2 I;  1XMO I;  4JI7 I;  2F4V E;  4NXM I;  4IFD E;  4FWD A;  2Z5B A;  4FWG A;  4MU3 A;  1XHK A;  4MYU A;  4JI1 I;  1NHI A;  1Z5C A;  1I94 I;  4OO1 A;  4JV5 I;  1S16 A;  1HR0 E;  2HHH E;  3PS2 A;  4DV3 E;  3HJC A;  5C0X D;  1IBK I;  4USK A;  1E3H A;  4DUY I;  1R6M A;  4JI5 I;  1YHC A;  4MU1 A;  4DPW A;  4JI2 E;  5JEA F;  2PO0 A;  4YY3 E;  2C38 B;  4I3H A;  2J7K A;  2C37 B;  4FW6 A;  3P76 A;  1Z0T A;  1EI1 A;  2AE8 A;  4MYT A;  4DV6 I;  1HNX I;  3M7N D;  4OO1 C;  4B3T I;  4LF7 I;  3JAM C;  3QT8 A;  1PIE A;  4LFC E;  5L3J A;  1KVK A;  1VIS A;  5BR8 I;  4B3R I;  4OO1 E;  4HAC B;  5IWA I;  3J7A G;  5LMU E;  4MU4 A;  2VF3 A;  3U1K A;  4ISA A;  4DR3 E;  3M7N G;  3Q6M A;  2O1V A;  1P42 A;  5IT9 C;  4JI8 E;  1B63 A;  4DV0 E;  3H1C A;  4X64 I;  4LF4 I;  2UUB I;  4K0K I;  3B8H A;  4ZVI A;  1Y6Z A;  1QZR A;  1MX0 A;  4DPY A;  4B3M I;  5GMD A;  1S4E A;  3L7Z A;  1IBL I;  2E1R A;  4BA1 A;  5FWK A;  2PO1 A;  1PVG A;  1Z0G A;  4GKJ E;  5JEA B;  2XEX A;  4DR5 E;  4LF8 I;  4Z7Y A;  4MQY A;  4R1F A;  4X62 I;  1HNW I;  4DV5 I;  2HFS A;  2Z5C A;  5EL9 A;  1Z0E A;  3HUL A;  3HKM A;  4YHH E;  4DV4 E;  3ZZ0 A;  4ED4 A;  2UXC I;  4LFB I;  4JI4 I;  5GME A;  1Z0V A;  2NN6 B;  1OYP A;  4KHP E;  4LPF A; 
#chains in the Genus database with same CATH homology
 2GO3 A;  4J3D A;  3P3C A;  4FW5 A;  4FW3 A;  5DRQ A;  5DRR A;  3PS3 A;  1XXE A;  4FW6 A;  3P76 A;  1YH8 A;  4LCF A;  4ISA A;  3P3E A;  4FW4 A;  3P3G A;  4U3B A;  3PS1 A;  2O3Z A;  4LCH A;  2IES A;  5DRO A;  5DRP A;  1P42 A;  4MQY A;  3UHM A;  4OZE A;  4LCG A;  2JT2 A;  3PS2 A;  3NZK A;  2IER A;  4OKG A;  2J65 A;  3U1Y A;  1YHC A;  2GO4 A;  4MDT A;  4U3D A;  2VES A;  4FW7 A;  4IS9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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