2GO3A

Crystal structure of aquifex aeolicus lpxc complexed with imidazole.
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
266
structure length
266
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Mechanistic Inferences from the Binding of Ligands to LpxC, a Metal-Dependent Deacetylase
pubmed doi rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
total genus 91
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2006-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 2go3A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 2go3A02
4FW7A 2J65A 3P3GA 4FW4A 4U3DA 2JT2A 4IS9A 2IESA 3P3EA 2GO3A 4LCGA 5DROA 4ISAA 4U3BA 5DRRA 2VESA 4LCFA 3PS1A 4MQYA 4OKGA 3NZKA 3PS2A 5DRQA 3UHMA 3P76A 4FW3A 2IERA 3P3CA 4LCHA 5DRPA 2O3ZA 3U1YA 2GO4A 1YHCA 4FW5A 4FW6A 4MDTA 1P42A 4J3DA 1XXEA 1YH8A 4OZEA 3PS3A
chains in the Genus database with same CATH superfamily
4FW7A 1H7SA 2VQFE 1XMQE 4PRXA 1K47A 3JAMC 3T1YI 4JI0I 4MU3A 3Q1QA 2ZBKB 5K36B 2HFSA 1N34E 4JI3I 4M1KA 1MU5A 2WNRB 3K17A 4USMA 4LFAI 4DR6E 1HNWE 1Z0CA 4IFDA 5JEAA 1KVKA 2PO0A 4JI6I 1HNZE 2X7IA 1XNRI 4IFDF 3HULA 5JEAF 4NBQA 3U1YA 4X65E 2GO4A 5DNXA 3ZZ0A 5A2QQ 1HR0E 1ZM9A 2F1DA 4DR1I 4AIDA 2JEBB 3P3GA 2V8PA 4OO1E 1UDNA 4P7AA 4HACB 3CDIA 1IBKI 2IOPA 1PKPA 3P3EA 2C37A 2Z5CA 2UXBE 3M6AA 4BA2A 1IBLE 2WP8B 5C0XA 2F4VE 2V34A 4DPYA 5C0XF 4I3HA 1VISA 2C39A 2O1VA 2V2QA 1HK7A 4FW9A 4IZKB 1Z5CA 2NN6B 4QNKA 4Z7YA 4YY3E 3OTOI 4ZVIA 1Z59A 4LF8E 2ZM6I 4USKA 4LFCI 4IZJD 4DV5E 1N0UA 1Z5BA 4MQYA 1BKNA 3PS2A 4DV0I 2AE8A 3K1JA 4AM3A 2O1TA 2GQ0A 2HK2A 4WUDA 1XNQI 2BM0A 4QNJA 3ZM7A 1RHYA 2BA1G 3T1HI 2BR2B 2JE6A 2CG9A 5K36A 3WU4A 2JT2A 2WNRA 3CWVA 4DU8A 4EMDA 3L7ZA 1I94E 3P06A 3ZZTA 1Y6ZA 4JI8E 4DPTA 4KHPI 5K36F 4DPWA 1E3HA 2LJPA 2CVEA 4DR4E 2E5LI 2IOQA 3NZKA 4JV5I 4JI8I 4OO1B 2VQEE 3P76A 2C38B 4JYAI 3P3CA 4LCHA 2JEBA 4JI7E 3M85D 4DUZE 2V2ZA 2HK3A 5FWKA 1EI1A 1H73A 4URLA 2VQEI 4X64I 3ZKDA 4JI2E 4DR3E 1ZXMA 1N33I 2PNMA 4NXMI 1N32I 3J80Q 2UU9E 2UUCE 2DEIA 1NHHA 1J5EE 4OX9E 4B3SI 2PO2A 4OKGA 1Z0WA 4JI1I 1DARA 4DR2I 4HXZA 3GCMA 5IWAI 4DR5I 5EKWA 2NN6A 3T1YE 4JI0E 2PNZA 1XMOI 2Z5BB 1FWLA 2NN6F 4JI3E 1RR9A 4LFAE 2R42A 5IT9Q 4JI6E 2X36A 1XNRE 4PU9A 4AIMA 2HHHI 4MU0A 3J81C 4DV1I 4B3TI 4HYMA 4DR1E 3WU3A 2BR2A 4NXNI 3PYGA 1IBKE 2UUAI 1XXEA 1EA6A 3PS3A 4GQUA 3LPSA 2CGEA 1A6FA 4JI5I 1Z0BA 1UDQA 4IFDD 5JEAD 4LF4I 2GO3A 4B3RI 4OO1A 2A2DA 4OO1F 5FLXQ 1N36E 3UHMA 1R6LA 3K85A 4MYUA 1N36I 4KQVA 3OTOE 4PRVA 1NHIA 2ZM6E 4DU7A 4LFCE 4DUYI 4AQYI 1XHKA 5C0XD 1HNXI 4DPUA 4BA1A 5GMEA 4DV0E 4U3BA 4DV2I 4IFDC 3PS1A 3DD6A 3KRNA 1MG7A 5JEAC 1XNQE 3H1CA 2CZ9A 3PRYA 3ZZUA 1FWKA 4X62I 2UUBI 1Z0VA 1IBMI 3J7AM 2ZITA 3T1HE 2BA0G 1Y4UA 4GKKI 2Z5BA 4WUBA 2UXDI 4LF6I 1B62A 1E3PA 2HKJA 4KHPE 3LNUA 2VF3A 3F0NA 4B3MI 3B4TA 1U2RA 2BM1A 2E5LE 5DROA 4JV5E 1PIEA 2J7KA 5DRRA 4DV3I 5EL9A 4JYAE 3M7NG 4UTGA 5C0XC 4X64E 5K36D 2BA1D 1UDOA 3WU5A 1N33E 4FW5A 1NZ0A 1P42A 5BR8I 4HACA 4NXME 1N32E 1FJGI 2J65A 1KTVA 1OJ4A 1USVA 4K0KI 2JEAB 4IS9A 3B82A 4B3SE 4FN5A 4FWDA 4JI1E 2BV3A 2WP8A 3WU6A 1ZM2A 4DR2E 1USUA 2C37B 1Y5YA 1FNMA 4RPFA 5IWAE 4DR5E 4BA2B 1PVGA 2O1WA 3D4JA 4FW3A 1XMOE 4LOMA 3H4LA 1FI4A 1RREA 4UT4A 4IZKA 4GKJI 1Y4SA 4IZJB 4LPFA 2UXCI 5K36C 2C39B 4U3DA 4MU1A 5A2QC 2HHHE 4HY1A 1KIJA 4DR7I 4ED4A 1OYPA 4B3TE 5LMUI 4DV1E 4LF9I 3V5RA 1N0VC 1KKHA 2NN6D 4NXNE 1B63A 4XTJA 2UUAE 4LF7I 2Q2EB 5FLXC 5DRPA 4JI4I 3GLLA 3B78A 4X66I 4JI5E 1YHCA 4FW6A 5ELWA 1Z0EA 5LMNI 4YHHI 2GS8A 4LF4E 4LFBI 3LTOA 4B3RE 3GMEA 1S16A 1R6MA 2IESA 2O1UA 4DV6I 4LF5I 2JE6B 4IFDE 3HKMA 5JEAE 2VQFI 1XMQI 3B8HA 3L7ZB 3GONA 3HJCA 2C38A 1QZRA 4MYTA 2AJ4A 1N34I 1UDSA 1ZM4A 4DR6I 1HNWI 1Z0GA 1ZM3A 2O3ZA 3PYEA 1Y60A 2NN6C 4DUYE 2DEJA 3Q6NA 4WUCA 1HNZI 2JEAA 4AQYE 3JAMQ 1HNXE 4JG4A 4OO1D 4X65I 2E1RA 4DV2E 1HR0I 1MX0A 3PYFA 5LL6R 5C0XE 4X62E 1VI7A 2UUBE 3J81Q 3V2UC 1IBME 4GKKE 4P52A 1NHJA 5DRQA 4LF6E 2PO2B 2UXDE 2UXBI 2Z5EA 5DNLA 4IZJA 2PO1B 1IBLI 1FKAE 4B3ME 1S4EA 2F4VI 1ZXNA 3U1KA 4MU4A 2A2CA 2PNZB 4DV3E 4N3OA 4LCGA 4OO1C 4Z7CA 4YY3I 4LF8I 3J80C 2XEXA 1UEKA 2BA0D 5BR8E 4DV5I 2HFUA 4IFDB 1FJGE 4DV4E 1OYSA 3QT8A 5JEAB 2PO0B 5K36E 4K0KE 1Z0TA 3QT5A 3M85G 1Z5AA 4FWGA 4DV4I 5GMDA 2PNLA 4DV7E 4FWHA 1H74A 3M7ND 5IT9C 1I94I 4GKJE 4DV7I 2Z5CB 2UXCE 4DR4I 3Q6MA 5C0XB 3CDJA 4J3DA 3ZKBA 3PYDA 4OZEA 4DPXA 4JI7I 4DUZI 1OYRA 4FW4A 2WW4A 4DR7E 2V2VA 2EFGA 2HKEA 5LMUE 4DXLA 1D6TA 4LF9E 1ELOA 4JI2I 4DR3I 1WUUA 4ISAA 2VESA 4LF7E 2OI2A 3QT7A 4LCFA 4BA1B 2PO1A 5L3JA 4JI4E 2UU9I 4X66E 1H72C 2UUCI 2NN6E 1J5EI 3J7AG 4OX9I 5LMNE 4YHHE 3QT6A 4LFBE 1H7UA 2IERA 2NPFA 4MDTA 4DV6E 4LF5E 4R1FA 1YH8A 2R3VA
chains in the Genus database with same CATH topology
4FW7A 2J65A 3P3GA 4FW4A 4U3DA 2JT2A 4IS9A 2IESA 3P3EA 2GO3A 4LCGA 5DROA 4ISAA 4U3BA 5DRRA 2VESA 4LCFA 3PS1A 4MQYA 4OKGA 3NZKA 3PS2A 5DRQA 3UHMA 3P76A 4FW3A 2IERA 3P3CA 4LCHA 5DRPA 2O3ZA 3U1YA 2GO4A 1YHCA 4FW5A 4FW6A 4MDTA 1P42A 4J3DA 1XXEA 1YH8A 4OZEA 3PS3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FW7 A;  2J65 A;  3P3G A;  4FW4 A;  4U3D A;  2JT2 A;  4IS9 A;  2IES A;  3P3E A;  2GO3 A;  4LCG A;  5DRO A;  4ISA A;  4U3B A;  5DRR A;  2VES A;  4LCF A;  3PS1 A;  4MQY A;  4OKG A;  3NZK A;  3PS2 A;  5DRQ A;  3UHM A;  3P76 A;  4FW3 A;  2IER A;  3P3C A;  4LCH A;  5DRP A;  2O3Z A;  3U1Y A;  2GO4 A;  1YHC A;  4FW5 A;  4FW6 A;  4MDT A;  1P42 A;  4J3D A;  1XXE A;  1YH8 A;  4OZE A;  3PS3 A; 
#chains in the Genus database with same CATH topology
 4FW7 A;  1H7S A;  2VQF E;  1XMQ E;  4PRX A;  1K47 A;  3JAM C;  3T1Y I;  4JI0 I;  4MU3 A;  3Q1Q A;  2ZBK B;  5K36 B;  2HFS A;  1N34 E;  4JI3 I;  4M1K A;  1MU5 A;  2WNR B;  3K17 A;  4USM A;  4LFA I;  4DR6 E;  1HNW E;  1Z0C A;  4IFD A;  5JEA A;  1KVK A;  2PO0 A;  4JI6 I;  1HNZ E;  2X7I A;  1XNR I;  4IFD F;  3HUL A;  5JEA F;  4NBQ A;  3U1Y A;  4X65 E;  2GO4 A;  5DNX A;  3ZZ0 A;  5A2Q Q;  1HR0 E;  1ZM9 A;  2F1D A;  4DR1 I;  4AID A;  2JEB B;  3P3G A;  2V8P A;  4OO1 E;  1UDN A;  4P7A A;  4HAC B;  3CDI A;  1IBK I;  2IOP A;  1PKP A;  3P3E A;  2C37 A;  2Z5C A;  2UXB E;  3M6A A;  4BA2 A;  1IBL E;  2WP8 B;  5C0X A;  2F4V E;  2V34 A;  4DPY A;  5C0X F;  4I3H A;  1VIS A;  2C39 A;  2O1V A;  2V2Q A;  1HK7 A;  4FW9 A;  4IZK B;  1Z5C A;  2NN6 B;  4QNK A;  4Z7Y A;  4YY3 E;  3OTO I;  4ZVI A;  1Z59 A;  4LF8 E;  2ZM6 I;  4USK A;  4LFC I;  4IZJ D;  4DV5 E;  1N0U A;  1Z5B A;  4MQY A;  1BKN A;  3PS2 A;  4DV0 I;  2AE8 A;  3K1J A;  4AM3 A;  2O1T A;  2GQ0 A;  2HK2 A;  4WUD A;  1XNQ I;  2BM0 A;  4QNJ A;  3ZM7 A;  1RHY A;  2BA1 G;  3T1H I;  2BR2 B;  2JE6 A;  2CG9 A;  5K36 A;  3WU4 A;  2JT2 A;  2WNR A;  3CWV A;  4DU8 A;  4EMD A;  3L7Z A;  1I94 E;  3P06 A;  3ZZT A;  1Y6Z A;  4JI8 E;  4DPT A;  4KHP I;  5K36 F;  4DPW A;  1E3H A;  2LJP A;  2CVE A;  4DR4 E;  2E5L I;  2IOQ A;  3NZK A;  4JV5 I;  4JI8 I;  4OO1 B;  2VQE E;  3P76 A;  2C38 B;  4JYA I;  3P3C A;  4LCH A;  2JEB A;  4JI7 E;  3M85 D;  4DUZ E;  2V2Z A;  2HK3 A;  5FWK A;  1EI1 A;  1H73 A;  4URL A;  2VQE I;  4X64 I;  3ZKD A;  4JI2 E;  4DR3 E;  1ZXM A;  1N33 I;  2PNM A;  4NXM I;  1N32 I;  3J80 Q;  2UU9 E;  2UUC E;  2DEI A;  1NHH A;  1J5E E;  4OX9 E;  4B3S I;  2PO2 A;  4OKG A;  1Z0W A;  4JI1 I;  1DAR A;  4DR2 I;  4HXZ A;  3GCM A;  5IWA I;  4DR5 I;  5EKW A;  2NN6 A;  3T1Y E;  4JI0 E;  2PNZ A;  1XMO I;  2Z5B B;  1FWL A;  2NN6 F;  4JI3 E;  1RR9 A;  4LFA E;  2R42 A;  5IT9 Q;  4JI6 E;  2X36 A;  1XNR E;  4PU9 A;  4AIM A;  2HHH I;  4MU0 A;  3J81 C;  4DV1 I;  4B3T I;  4HYM A;  4DR1 E;  3WU3 A;  2BR2 A;  4NXN I;  3PYG A;  1IBK E;  2UUA I;  1XXE A;  1EA6 A;  3PS3 A;  4GQU A;  3LPS A;  2CGE A;  1A6F A;  4JI5 I;  1Z0B A;  1UDQ A;  4IFD D;  5JEA D;  4LF4 I;  2GO3 A;  4B3R I;  4OO1 A;  2A2D A;  4OO1 F;  5FLX Q;  1N36 E;  3UHM A;  1R6L A;  3K85 A;  4MYU A;  1N36 I;  4KQV A;  3OTO E;  4PRV A;  1NHI A;  2ZM6 E;  4DU7 A;  4LFC E;  4DUY I;  4AQY I;  1XHK A;  5C0X D;  1HNX I;  4DPU A;  4BA1 A;  5GME A;  4DV0 E;  4U3B A;  4DV2 I;  4IFD C;  3PS1 A;  3DD6 A;  3KRN A;  1MG7 A;  5JEA C;  1XNQ E;  3H1C A;  2CZ9 A;  3PRY A;  3ZZU A;  1FWK A;  4X62 I;  2UUB I;  1Z0V A;  1IBM I;  3J7A M;  2ZIT A;  3T1H E;  2BA0 G;  1Y4U A;  4GKK I;  2Z5B A;  4WUB A;  2UXD I;  4LF6 I;  1B62 A;  1E3P A;  2HKJ A;  4KHP E;  3LNU A;  2VF3 A;  3F0N A;  4B3M I;  3B4T A;  1U2R A;  2BM1 A;  2E5L E;  5DRO A;  4JV5 E;  1PIE A;  2J7K A;  5DRR A;  4DV3 I;  5EL9 A;  4JYA E;  3M7N G;  4UTG A;  5C0X C;  4X64 E;  5K36 D;  2BA1 D;  1UDO A;  3WU5 A;  1N33 E;  4FW5 A;  1NZ0 A;  1P42 A;  5BR8 I;  4HAC A;  4NXM E;  1N32 E;  1FJG I;  2J65 A;  1KTV A;  1OJ4 A;  1USV A;  4K0K I;  2JEA B;  4IS9 A;  3B82 A;  4B3S E;  4FN5 A;  4FWD A;  4JI1 E;  2BV3 A;  2WP8 A;  3WU6 A;  1ZM2 A;  4DR2 E;  1USU A;  2C37 B;  1Y5Y A;  1FNM A;  4RPF A;  5IWA E;  4DR5 E;  4BA2 B;  1PVG A;  2O1W A;  3D4J A;  4FW3 A;  1XMO E;  4LOM A;  3H4L A;  1FI4 A;  1RRE A;  4UT4 A;  4IZK A;  4GKJ I;  1Y4S A;  4IZJ B;  4LPF A;  2UXC I;  5K36 C;  2C39 B;  4U3D A;  4MU1 A;  5A2Q C;  2HHH E;  4HY1 A;  1KIJ A;  4DR7 I;  4ED4 A;  1OYP A;  4B3T E;  5LMU I;  4DV1 E;  4LF9 I;  3V5R A;  1N0V C;  1KKH A;  2NN6 D;  4NXN E;  1B63 A;  4XTJ A;  2UUA E;  4LF7 I;  2Q2E B;  5FLX C;  5DRP A;  4JI4 I;  3GLL A;  3B78 A;  4X66 I;  4JI5 E;  1YHC A;  4FW6 A;  5ELW A;  1Z0E A;  5LMN I;  4YHH I;  2GS8 A;  4LF4 E;  4LFB I;  3LTO A;  4B3R E;  3GME A;  1S16 A;  1R6M A;  2IES A;  2O1U A;  4DV6 I;  4LF5 I;  2JE6 B;  4IFD E;  3HKM A;  5JEA E;  2VQF I;  1XMQ I;  3B8H A;  3L7Z B;  3GON A;  3HJC A;  2C38 A;  1QZR A;  4MYT A;  2AJ4 A;  1N34 I;  1UDS A;  1ZM4 A;  4DR6 I;  1HNW I;  1Z0G A;  1ZM3 A;  2O3Z A;  3PYE A;  1Y60 A;  2NN6 C;  4DUY E;  2DEJ A;  3Q6N A;  4WUC A;  1HNZ I;  2JEA A;  4AQY E;  3JAM Q;  1HNX E;  4JG4 A;  4OO1 D;  4X65 I;  2E1R A;  4DV2 E;  1HR0 I;  1MX0 A;  3PYF A;  5LL6 R;  5C0X E;  4X62 E;  1VI7 A;  2UUB E;  3J81 Q;  3V2U C;  1IBM E;  4GKK E;  4P52 A;  1NHJ A;  5DRQ A;  4LF6 E;  2PO2 B;  2UXD E;  2UXB I;  2Z5E A;  5DNL A;  4IZJ A;  2PO1 B;  1IBL I;  1FKA E;  4B3M E;  1S4E A;  2F4V I;  1ZXN A;  3U1K A;  4MU4 A;  2A2C A;  2PNZ B;  4DV3 E;  4N3O A;  4LCG A;  4OO1 C;  4Z7C A;  4YY3 I;  4LF8 I;  3J80 C;  2XEX A;  1UEK A;  2BA0 D;  5BR8 E;  4DV5 I;  2HFU A;  4IFD B;  1FJG E;  4DV4 E;  1OYS A;  3QT8 A;  5JEA B;  2PO0 B;  5K36 E;  4K0K E;  1Z0T A;  3QT5 A;  3M85 G;  1Z5A A;  4FWG A;  4DV4 I;  5GMD A;  2PNL A;  4DV7 E;  4FWH A;  1H74 A;  3M7N D;  5IT9 C;  1I94 I;  4GKJ E;  4DV7 I;  2Z5C B;  2UXC E;  4DR4 I;  3Q6M A;  5C0X B;  3CDJ A;  4J3D A;  3ZKB A;  3PYD A;  4OZE A;  4DPX A;  4JI7 I;  4DUZ I;  1OYR A;  4FW4 A;  2WW4 A;  4DR7 E;  2V2V A;  2EFG A;  2HKE A;  5LMU E;  4DXL A;  1D6T A;  4LF9 E;  1ELO A;  4JI2 I;  4DR3 I;  1WUU A;  4ISA A;  2VES A;  4LF7 E;  2OI2 A;  3QT7 A;  4LCF A;  4BA1 B;  2PO1 A;  5L3J A;  4JI4 E;  2UU9 I;  4X66 E;  1H72 C;  2UUC I;  2NN6 E;  1J5E I;  3J7A G;  4OX9 I;  5LMN E;  4YHH E;  3QT6 A;  4LFB E;  1H7U A;  2IER A;  2NPF A;  4MDT A;  4DV6 E;  4LF5 E;  4R1F A;  1YH8 A;  2R3V A; 
#chains in the Genus database with same CATH homology
 4FW7 A;  2J65 A;  3P3G A;  4FW4 A;  4U3D A;  2JT2 A;  4IS9 A;  2IES A;  3P3E A;  2GO3 A;  4LCG A;  5DRO A;  4ISA A;  4U3B A;  5DRR A;  2VES A;  4LCF A;  3PS1 A;  4MQY A;  4OKG A;  3NZK A;  3PS2 A;  5DRQ A;  3UHM A;  3P76 A;  4FW3 A;  2IER A;  3P3C A;  4LCH A;  5DRP A;  2O3Z A;  3U1Y A;  2GO4 A;  1YHC A;  4FW5 A;  4FW6 A;  4MDT A;  1P42 A;  4J3D A;  1XXE A;  1YH8 A;  4OZE A;  3PS3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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