2GO3A

Crystal structure of aquifex aeolicus lpxc complexed with imidazole.
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
266
structure length
266
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic Inferences from the Binding of Ligands to LpxC, a Metal-Dependent Deacetylase
pubmed doi rcsb
molecule tags Hydrolase
source organism Aquifex aeolicus
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 91
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2006-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 2go3A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 2go3A02
3PS1A 4J3DA 2JT2A 2VESA 4FW6A 1YHCA 4OKGA 3U1YA 4FW4A 5DRRA 4FW5A 1YH8A 2O3ZA 1XXEA 4FW3A 4FW7A 2GO4A 2IESA 4ISAA 4MQYA 1P42A 3P3CA 3PS3A 2GO3A 2IERA 4OZEA 3UHMA 5DRPA 4LCGA 3P3EA 4U3DA 4MDTA 5DROA 3PS2A 3P76A 4LCHA 2J65A 4IS9A 4U3BA 4LCFA 5DRQA 3NZKA 3P3GA
chains in the Genus database with same CATH superfamily
4JI7E 2CVEA 2V2ZA 3K1JA 2UUCE 5JEAD 4DR7I 4JI1E 4LF8I 1S4EA 3M85D 4USKA 3HKMA 4B3TE 1FKAE 1NHIA 4LCGA 1OJ4A 2HK3A 2WW4A 4K0KI 1HNXI 4DV1E 1OYPA 4JI7I 4OO1D 2C37B 4USMA 2O1UA 2UUCI 1XNRE 4JI1I 4X65E 1NZ0A 1USUA 2BA0D 1Y4SA 3Q1QA 1Z0CA 4MU1A 4AQYE 4B3TI 5L3JA 4DV1I 1OYSA 1XNRI 4X65I 2PO2B 4JI0E 2WNRB 1Z0VA 2BR2A 4NBQA 4AQYI 4AIMA 1XMQE 1PKPA 4LF9E 2XEXA 1ZXNA 4LFBE 1N0UA 2X36A 2R3VA 1ZM2A 3PS2A 3P76A 3D4JA 1Z0BA 4UTGA 4JI0I 1HR0E 5K36B 1ZM4A 1PVGA 5A2QC 1FNMA 1XMQI 4DXLA 4LF9I 4LFBI 3U1YA 2CGEA 4B3ME 3U1KA 4IFDC 2NN6C 1HR0I 2IERA 4X66E 2O1TA 4R1FA 3KRNA 2C38A 2EFGA 5C0XD 4IS9A 2WP8A 4B3MI 2Z5BA 4P52A 1N32E 4IZJA 1UDSA 4LF4E 4LOMA 4X66I 2OI2A 4GKKE 2E1RA 1VISA 4HACA 2ZBKB 2ZITA 1S16A 5JEAF 4I3HA 2AJ4A 1N32I 2IOQA 1QZRA 1RREA 3B78A 4MU0A 4LF4I 2HKEA 4UT4A 2CZ9A 4P7AA 5ELWA 4GKKI 2UXDE 2BR2B 1IBME 2NPFA 4OO1F 2Z5EA 3M6AA 4DR2E 4ED4A 3HULA 2X7IA 2UXDI 1FWKA 1IBMI 4NXNE 2E5LE 2C39B 4IFDA 3J80C 4DR2I 3Q6MA 3B82A 4MU4A 2F4VE 4HXZA 3CDJA 4FW9A 4DPTA 3NZKA 3P3GA 1XNQE 2C38B 3J80Q 4NXNI 1XHKA 2E5LI 2PNZA 4IZKA 4OKGA 5JEAE 1N34E 5FLXQ 1BKNA 2WP8B 3H1CA 1R6MA 4IZJB 2UU9I 1Z0WA 4LF5E 2F4VI 4JG4A 2BM0A 4X64E 4OO1E 4JYAE 4DPWA 4BA2A 1Y4UA 1N34I 4N3OA 3CWVA 4JI3E 2PNLA 2F1DA 4PRXA 2NN6D 3J81Q 4U3BA 4XTJA 2VQFE 5K36D 4B3RE 3Q6NA 4HYMA 5C0XF 2Z5CA 1I94E 4X64I 4JYAI 1KVKA 4JI3I 4JI2E 2VQFI 3J7AM 3CDIA 4GQUA 4X62E 4B3RI 4B3SE 2V34A 2AE8A 4JV5E 4DUYE 4DR6E 1I94I 2V2QA 3ZM7A 2GQ0A 4M1KA 4LF6E 4JI2I 4IFDB 4DR1E 2NN6B 5IT9Q 1KTVA 2JEAA 4X62I 4NXME 4DU8A 4B3SI 1ZM9A 2JT2A 2PO1A 3PYDA 4JV5I 4DUYI 4DR6I 5DRRA 4FW3A 3ZZ0A 1UDOA 4LF6I 1Z5AA 1R6LA 4IZKB 2PNZB 4DR1I 4LFCE 1H73A 3WU6A 4YHHE 4NXMI 1VI7A 3OTOE 4DV4E 5C0XE 4MYTA 4LCHA 2J65A 3QT7A 5JEAC 1D6TA 1USVA 1Z5CA 4LPFA 4JI5E 2PO0A 1B63A 4LFCI 2Q2EB 4YHHI 1Y6ZA 2VESA 3OTOI 1KKHA 4DV4I 4JI8E 1E3PA 2O3ZA 4OO1C 4WUCA 1OYRA 2Z5CB 3L7ZA 3JAMC 2UXCE 4LF7E 3T1HE 3WU3A 5DNXA 4JI5I 2V8PA 4BA1A 1UEKA 1WUUA 2DEIA 4DR5E 4MYUA 4JI6E 1J5EE 4JI8I 3JAMQ 4QNJA 4KQVA 3F0NA 2UXCI 4FWDA 1Z0GA 3T1HI 4LF7I 2BA1D 2O1VA 2R42A 5K36F 1E3HA 3H4LA 4DR4E 3LPSA 4IZJD 4JI6I 2JEAB 1J5EI 2IOPA 1Y60A 5DNLA 4AIDA 2O1WA 3V5RA 4JI4E 3GMEA 4DR4I 3GLLA 1UDNA 2CG9A 5FLXC 3M7NG 4LCFA 5JEAA 1N36E 1HNXE 3GONA 2J7KA 4J3DA 1HNWE 3J7AG 3PYEA 4Z7CA 3LNUA 2PO0B 2IESA 2Z5BB 4DU7A 5C0XC 4LFAE 1P42A 1NHHA 4OO1A 1XMOE 3J81C 4DV7E 2UUBE 3K85A 3ZZTA 1N36I 4MDTA 3K17A 1FI4A 2HFSA 3PRYA 1XNQI 1HNWI 1N33E 5GMEA 1H7SA 4LF8E 3L7ZB 4HACB 3HJCA 4WUBA 1MG7A 5K36E 4IFDD 4DV0E 1Z59A 2BA1G 3QT6A 1NHJA 4LFAI 4LF5I 1XMOI 2UUBI 4DV7I 4FN5A 4FW6A 1RHYA 1N33I 4FW7A 2A2CA 2GO4A 3P06A 5EL9A 3WU5A 1IBKE 4DV0I 3PS3A 5EKWA 2GS8A 2PNMA 4DV6E 1DARA 5IT9C 3GCMA 2BV3A 4DV2E 5BR8E 2BM1A 4PRVA 5LMUE 4YY3E 1IBKI 3T1YE 2VF3A 2LJPA 2ZM6E 4DV6I 1Z5BA 1YHCA 4GKJE 5LMNE 4Z7YA 5JEAB 4DV2I 2UXBE 4ISAA 3V2UC 4MQYA 5BR8I 5LMUI 4YY3I 5C0XA 3T1YI 3ZZUA 3P3EA 2HKJA 2ZM6I 4DR3E 2DEJA 4ZVIA 5DROA 4DPUA 4DV5E 4GKJI 1K47A 4PU9A 4OO1B 1KIJA 1ZXMA 3LTOA 1Y5YA 5LMNI 2UXBI 1EI1A 1EA6A 2JEBA 1IBLE 4BA2B 4URLA 3M7ND 4DR3I 2HHHE 3M85G 2C39A 5IWAE 2HK2A 1U2RA 1Z0TA 4FW5A 4DV5I 3B8HA 2JE6A 2VQEE 4DV3E 5A2QQ 1H74A 5K36C 3UHMA 1IBLI 4EMDA 2BA0G 3QT5A 3WU4A 1ELOA 2HHHI 5IWAI 2UUAE 2VQEI 4DV3I 5DRQA 3PYFA 3QT8A 4IFDF 4HY1A 2NN6F 1B62A 1UDQA 2HFUA 1MX0A 2A2DA 1ZM3A 4DR5I 2C37A 3P3CA 2UUAI 4DPYA 3PYGA 4OZEA 5DRPA 1FJGE 4U3DA 2PO1B 5FWKA 4AM3A 3ZKBA 4DPXA 4KHPE 5LL6R 5C0XB 3B4TA 4OX9E 2PO2A 1H72C 4QNKA 3PS1A 1FJGI 4WUDA 4MU3A 1RR9A 1FWLA 2WNRA 4FW4A 4DUZE 4JI4I 1YH8A 1HNZE 1XXEA 4KHPI 1PIEA 2JEBB 1H7UA 3DD6A 1Z0EA 4FWHA 2GO3A 4OX9I 1MU5A 2NN6A 4FWGA 3ZKDA 5K36A 1HK7A 1A6FA 4DR7E 2JE6B 4RPFA 2UU9E 2V2VA 4DUZI 4IFDE 2NN6E 1HNZI 1N0VC 4BA1B 4K0KE 5GMDA
chains in the Genus database with same CATH topology
3PS1A 4J3DA 2JT2A 2VESA 4FW6A 1YHCA 4OKGA 3U1YA 4FW4A 5DRRA 4FW5A 1YH8A 2O3ZA 1XXEA 4FW3A 4FW7A 2GO4A 2IESA 4ISAA 4MQYA 1P42A 3P3CA 3PS3A 2GO3A 2IERA 4OZEA 3UHMA 5DRPA 4LCGA 3P3EA 4U3DA 4MDTA 5DROA 3PS2A 3P76A 4LCHA 2J65A 4IS9A 4U3BA 4LCFA 5DRQA 3NZKA 3P3GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PS1 A;  4J3D A;  2JT2 A;  2VES A;  4FW6 A;  1YHC A;  4OKG A;  3U1Y A;  4FW4 A;  5DRR A;  4FW5 A;  1YH8 A;  2O3Z A;  1XXE A;  4FW3 A;  4FW7 A;  2GO4 A;  2IES A;  4ISA A;  4MQY A;  1P42 A;  3P3C A;  3PS3 A;  2GO3 A;  2IER A;  4OZE A;  3UHM A;  5DRP A;  4LCG A;  3P3E A;  4U3D A;  4MDT A;  5DRO A;  3PS2 A;  3P76 A;  4LCH A;  2J65 A;  4IS9 A;  4U3B A;  4LCF A;  5DRQ A;  3NZK A;  3P3G A; 
#chains in the Genus database with same CATH topology
 4JI7 E;  2CVE A;  2V2Z A;  3K1J A;  2UUC E;  5JEA D;  4DR7 I;  4JI1 E;  4LF8 I;  1S4E A;  3M85 D;  4USK A;  3HKM A;  4B3T E;  1FKA E;  1NHI A;  4LCG A;  1OJ4 A;  2HK3 A;  2WW4 A;  4K0K I;  1HNX I;  4DV1 E;  1OYP A;  4JI7 I;  4OO1 D;  2C37 B;  4USM A;  2O1U A;  2UUC I;  1XNR E;  4JI1 I;  4X65 E;  1NZ0 A;  1USU A;  2BA0 D;  1Y4S A;  3Q1Q A;  1Z0C A;  4MU1 A;  4AQY E;  4B3T I;  5L3J A;  4DV1 I;  1OYS A;  1XNR I;  4X65 I;  2PO2 B;  4JI0 E;  2WNR B;  1Z0V A;  2BR2 A;  4NBQ A;  4AQY I;  4AIM A;  1XMQ E;  1PKP A;  4LF9 E;  2XEX A;  1ZXN A;  4LFB E;  1N0U A;  2X36 A;  2R3V A;  1ZM2 A;  3PS2 A;  3P76 A;  3D4J A;  1Z0B A;  4UTG A;  4JI0 I;  1HR0 E;  5K36 B;  1ZM4 A;  1PVG A;  5A2Q C;  1FNM A;  1XMQ I;  4DXL A;  4LF9 I;  4LFB I;  3U1Y A;  2CGE A;  4B3M E;  3U1K A;  4IFD C;  2NN6 C;  1HR0 I;  2IER A;  4X66 E;  2O1T A;  4R1F A;  3KRN A;  2C38 A;  2EFG A;  5C0X D;  4IS9 A;  2WP8 A;  4B3M I;  2Z5B A;  4P52 A;  1N32 E;  4IZJ A;  1UDS A;  4LF4 E;  4LOM A;  4X66 I;  2OI2 A;  4GKK E;  2E1R A;  1VIS A;  4HAC A;  2ZBK B;  2ZIT A;  1S16 A;  5JEA F;  4I3H A;  2AJ4 A;  1N32 I;  2IOQ A;  1QZR A;  1RRE A;  3B78 A;  4MU0 A;  4LF4 I;  2HKE A;  4UT4 A;  2CZ9 A;  4P7A A;  5ELW A;  4GKK I;  2UXD E;  2BR2 B;  1IBM E;  2NPF A;  4OO1 F;  2Z5E A;  3M6A A;  4DR2 E;  4ED4 A;  3HUL A;  2X7I A;  2UXD I;  1FWK A;  1IBM I;  4NXN E;  2E5L E;  2C39 B;  4IFD A;  3J80 C;  4DR2 I;  3Q6M A;  3B82 A;  4MU4 A;  2F4V E;  4HXZ A;  3CDJ A;  4FW9 A;  4DPT A;  3NZK A;  3P3G A;  1XNQ E;  2C38 B;  3J80 Q;  4NXN I;  1XHK A;  2E5L I;  2PNZ A;  4IZK A;  4OKG A;  5JEA E;  1N34 E;  5FLX Q;  1BKN A;  2WP8 B;  3H1C A;  1R6M A;  4IZJ B;  2UU9 I;  1Z0W A;  4LF5 E;  2F4V I;  4JG4 A;  2BM0 A;  4X64 E;  4OO1 E;  4JYA E;  4DPW A;  4BA2 A;  1Y4U A;  1N34 I;  4N3O A;  3CWV A;  4JI3 E;  2PNL A;  2F1D A;  4PRX A;  2NN6 D;  3J81 Q;  4U3B A;  4XTJ A;  2VQF E;  5K36 D;  4B3R E;  3Q6N A;  4HYM A;  5C0X F;  2Z5C A;  1I94 E;  4X64 I;  4JYA I;  1KVK A;  4JI3 I;  4JI2 E;  2VQF I;  3J7A M;  3CDI A;  4GQU A;  4X62 E;  4B3R I;  4B3S E;  2V34 A;  2AE8 A;  4JV5 E;  4DUY E;  4DR6 E;  1I94 I;  2V2Q A;  3ZM7 A;  2GQ0 A;  4M1K A;  4LF6 E;  4JI2 I;  4IFD B;  4DR1 E;  2NN6 B;  5IT9 Q;  1KTV A;  2JEA A;  4X62 I;  4NXM E;  4DU8 A;  4B3S I;  1ZM9 A;  2JT2 A;  2PO1 A;  3PYD A;  4JV5 I;  4DUY I;  4DR6 I;  5DRR A;  4FW3 A;  3ZZ0 A;  1UDO A;  4LF6 I;  1Z5A A;  1R6L A;  4IZK B;  2PNZ B;  4DR1 I;  4LFC E;  1H73 A;  3WU6 A;  4YHH E;  4NXM I;  1VI7 A;  3OTO E;  4DV4 E;  5C0X E;  4MYT A;  4LCH A;  2J65 A;  3QT7 A;  5JEA C;  1D6T A;  1USV A;  1Z5C A;  4LPF A;  4JI5 E;  2PO0 A;  1B63 A;  4LFC I;  2Q2E B;  4YHH I;  1Y6Z A;  2VES A;  3OTO I;  1KKH A;  4DV4 I;  4JI8 E;  1E3P A;  2O3Z A;  4OO1 C;  4WUC A;  1OYR A;  2Z5C B;  3L7Z A;  3JAM C;  2UXC E;  4LF7 E;  3T1H E;  3WU3 A;  5DNX A;  4JI5 I;  2V8P A;  4BA1 A;  1UEK A;  1WUU A;  2DEI A;  4DR5 E;  4MYU A;  4JI6 E;  1J5E E;  4JI8 I;  3JAM Q;  4QNJ A;  4KQV A;  3F0N A;  2UXC I;  4FWD A;  1Z0G A;  3T1H I;  4LF7 I;  2BA1 D;  2O1V A;  2R42 A;  5K36 F;  1E3H A;  3H4L A;  4DR4 E;  3LPS A;  4IZJ D;  4JI6 I;  2JEA B;  1J5E I;  2IOP A;  1Y60 A;  5DNL A;  4AID A;  2O1W A;  3V5R A;  4JI4 E;  3GME A;  4DR4 I;  3GLL A;  1UDN A;  2CG9 A;  5FLX C;  3M7N G;  4LCF A;  5JEA A;  1N36 E;  1HNX E;  3GON A;  2J7K A;  4J3D A;  1HNW E;  3J7A G;  3PYE A;  4Z7C A;  3LNU A;  2PO0 B;  2IES A;  2Z5B B;  4DU7 A;  5C0X C;  4LFA E;  1P42 A;  1NHH A;  4OO1 A;  1XMO E;  3J81 C;  4DV7 E;  2UUB E;  3K85 A;  3ZZT A;  1N36 I;  4MDT A;  3K17 A;  1FI4 A;  2HFS A;  3PRY A;  1XNQ I;  1HNW I;  1N33 E;  5GME A;  1H7S A;  4LF8 E;  3L7Z B;  4HAC B;  3HJC A;  4WUB A;  1MG7 A;  5K36 E;  4IFD D;  4DV0 E;  1Z59 A;  2BA1 G;  3QT6 A;  1NHJ A;  4LFA I;  4LF5 I;  1XMO I;  2UUB I;  4DV7 I;  4FN5 A;  4FW6 A;  1RHY A;  1N33 I;  4FW7 A;  2A2C A;  2GO4 A;  3P06 A;  5EL9 A;  3WU5 A;  1IBK E;  4DV0 I;  3PS3 A;  5EKW A;  2GS8 A;  2PNM A;  4DV6 E;  1DAR A;  5IT9 C;  3GCM A;  2BV3 A;  4DV2 E;  5BR8 E;  2BM1 A;  4PRV A;  5LMU E;  4YY3 E;  1IBK I;  3T1Y E;  2VF3 A;  2LJP A;  2ZM6 E;  4DV6 I;  1Z5B A;  1YHC A;  4GKJ E;  5LMN E;  4Z7Y A;  5JEA B;  4DV2 I;  2UXB E;  4ISA A;  3V2U C;  4MQY A;  5BR8 I;  5LMU I;  4YY3 I;  5C0X A;  3T1Y I;  3ZZU A;  3P3E A;  2HKJ A;  2ZM6 I;  4DR3 E;  2DEJ A;  4ZVI A;  5DRO A;  4DPU A;  4DV5 E;  4GKJ I;  1K47 A;  4PU9 A;  4OO1 B;  1KIJ A;  1ZXM A;  3LTO A;  1Y5Y A;  5LMN I;  2UXB I;  1EI1 A;  1EA6 A;  2JEB A;  1IBL E;  4BA2 B;  4URL A;  3M7N D;  4DR3 I;  2HHH E;  3M85 G;  2C39 A;  5IWA E;  2HK2 A;  1U2R A;  1Z0T A;  4FW5 A;  4DV5 I;  3B8H A;  2JE6 A;  2VQE E;  4DV3 E;  5A2Q Q;  1H74 A;  5K36 C;  3UHM A;  1IBL I;  4EMD A;  2BA0 G;  3QT5 A;  3WU4 A;  1ELO A;  2HHH I;  5IWA I;  2UUA E;  2VQE I;  4DV3 I;  5DRQ A;  3PYF A;  3QT8 A;  4IFD F;  4HY1 A;  2NN6 F;  1B62 A;  1UDQ A;  2HFU A;  1MX0 A;  2A2D A;  1ZM3 A;  4DR5 I;  2C37 A;  3P3C A;  2UUA I;  4DPY A;  3PYG A;  4OZE A;  5DRP A;  1FJG E;  4U3D A;  2PO1 B;  5FWK A;  4AM3 A;  3ZKB A;  4DPX A;  4KHP E;  5LL6 R;  5C0X B;  3B4T A;  4OX9 E;  2PO2 A;  1H72 C;  4QNK A;  3PS1 A;  1FJG I;  4WUD A;  4MU3 A;  1RR9 A;  1FWL A;  2WNR A;  4FW4 A;  4DUZ E;  4JI4 I;  1YH8 A;  1HNZ E;  1XXE A;  4KHP I;  1PIE A;  2JEB B;  1H7U A;  3DD6 A;  1Z0E A;  4FWH A;  2GO3 A;  4OX9 I;  1MU5 A;  2NN6 A;  4FWG A;  3ZKD A;  5K36 A;  1HK7 A;  1A6F A;  4DR7 E;  2JE6 B;  4RPF A;  2UU9 E;  2V2V A;  4DUZ I;  4IFD E;  2NN6 E;  1HNZ I;  1N0V C;  4BA1 B;  4K0K E;  5GMD A; 
#chains in the Genus database with same CATH homology
 3PS1 A;  4J3D A;  2JT2 A;  2VES A;  4FW6 A;  1YHC A;  4OKG A;  3U1Y A;  4FW4 A;  5DRR A;  4FW5 A;  1YH8 A;  2O3Z A;  1XXE A;  4FW3 A;  4FW7 A;  2GO4 A;  2IES A;  4ISA A;  4MQY A;  1P42 A;  3P3C A;  3PS3 A;  2GO3 A;  2IER A;  4OZE A;  3UHM A;  5DRP A;  4LCG A;  3P3E A;  4U3D A;  4MDT A;  5DRO A;  3PS2 A;  3P76 A;  4LCH A;  2J65 A;  4IS9 A;  4U3B A;  4LCF A;  5DRQ A;  3NZK A;  3P3G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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