2GO3A

Crystal structure of aquifex aeolicus lpxc complexed with imidazole.
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
266
structure length
266
Chain Sequence
b'GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Mechanistic Inferences from the Binding of Ligands to LpxC, a Metal-Dependent Deacetylase
pubmed doi rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
total genus 91
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2006-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 2go3A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 2go3A02
4J3DA 4FW5A 3PS1A 2VESA 4LCFA 4MQYA 2JT2A 2GO4A 4OKGA 3U1YA 5DROA 4FW7A 1YHCA 2J65A 1XXEA 3P3CA 3P76A 5DRPA 4LCHA 4LCGA 3P3EA 1P42A 1YH8A 5DRRA 5DRQA 2IERA 4U3DA 4ISAA 3UHMA 4MDTA 4OZEA 4FW3A 2O3ZA 4FW6A 4FW4A 4IS9A 3NZKA 2IESA 3PS2A 2GO3A 4U3BA 3P3GA 3PS3A
chains in the Genus database with same CATH superfamily
4B3ME 1N33E 4IZKA 4IFDC 4DV7I 4B3RE 2V2VA 2OI2A 4JI6I 1BKNA 3ZZUA 1Z5CA 4DV0E 4LFAI 3D4JA 4DPYA 2UUCI 1FI4A 4DV6I 5FWKA 4DV4E 2HHHI 2Z5CB 1Z0TA 4OO1A 4X66E 4IS9A 1K47A 4HACB 1MU5A 3LPSA 4AQYI 2F1DA 3GONA 2JEBA 4QNKA 4KHPI 1Z0VA 1ZM2A 4FW5A 2BM1A 3PS1A 4USKA 1VISA 4DPWA 1Z59A 2HFSA 3U1YA 4PU9A 1HK7A 1OJ4A 3Q6MA 3J80C 3J7AM 2WP8A 3H4LA 4R1FA 2HKEA 3K1JA 1KTVA 4DR5E 4OO1F 4JI4E 4OZEA 1Z0CA 1IBKI 5C0XB 1FKAE 3JAMC 4LF4E 4X65I 4IFDD 3M85G 4LF5I 3Q6NA 3OTOE 4JI3I 1E3HA 4B3SI 4DV2E 1UDSA 3L7ZA 4DR3I 2JT2A 4OKGA 2BA1D 3ZKDA 5K36B 1XMOE 4IFDA 4FWDA 4LCGA 1YH8A 4JV5I 3U1KA 1NHIA 3UHMA 3V2UC 4DV1E 2UU9I 1FJGI 4YY3I 4IZJD 2UUAI 3PS2A 4DU8A 2VQEE 1ZM9A 4MU4A 2O1WA 1D6TA 4GKJE 2C38B 5A2QC 1IBLE 4J3DA 3LNUA 4LFCI 3ZZ0A 1ZM3A 3T1HI 4LCFA 4JI1E 2IOQA 4WUDA 3Q1QA 4IFDF 5GMEA 4FW7A 4DV7E 4MU1A 4EMDA 3T1YE 1IBMI 1Z5BA 4IZJA 5DRQA 2HKJA 1EA6A 5FLXC 4LFAE 2UUCE 3M7ND 4DV6E 2HHHE 1H74A 4HXZA 1Y5YA 3B82A 2E5LI 2WNRA 2PNLA 4IZKB 4AQYE 1N0UA 5L3JA 2ZBKB 2CGEA 1S16A 5JEAD 2PNMA 1XXEA 4K0KI 1MX0A 2V8PA 3PYDA 2WW4A 4OO1B 4DUYI 2O3ZA 2LJPA 2UXBI 1N36I 1ZXNA 1IBKE 2ZM6E 2JEBB 2BV3A 4DR4E 2VF3A 4LF5E 1Y4UA 2BA0G 4LF7I 3PRYA 4JI3E 4X64I 4B3SE 4AIDA 4JI2I 2X7IA 3HJCA 4NXNI 2WP8B 3B78A 1QZRA 2VQFI 4DR3E 3ZM7A 2C37A 5K36E 1Z0BA 4U3DA 1H72C 4FWHA 4DR2I 4FW3A 2GQ0A 2V34A 4MU3A 2BR2B 3GMEA 3K85A 4Z7CA 2UU9E 3WU5A 1FJGE 4YY3E 2UUAE 4DV5E 5EKWA 2UXCI 2DEIA 4NBQA 3J81C 2IOPA 3HKMA 3L7ZB 1XMQI 4ZVIA 4UT4A 2UUBI 5C0XC 3T1HE 4LFCE 1UDNA 5JEAE 5LMUE 4IFDB 2O1UA 2F4VI 4X62E 4DUZI 5DNLA 2NN6E 1USUA 1HR0I 4LOMA 4BA1A 2IESA 3CDJA 3DD6A 2O1VA 5IWAE 2PO1A 2R42A 5IT9C 5K36C 4I3HA 3PYGA 2AE8A 2E5LE 2PNZB 4Z7YA 5DROA 4LF8I 1U2RA 4KQVA 4IZJB 2Z5EA 1HNZE 5DRRA 5BR8I 4JI5I 1NZ0A 1NHHA 3M6AA 1N34E 1N32I 4LFBI 4K0KE 4HYMA 1ZXMA 4HACA 3ZKBA 3F0NA 1N33I 3V5RA 5JEAC 4ED4A 5C0XD 4DUYE 1Z0EA 2UXBE 2WNRB 1N36E 2NN6C 4JI7E 4LF7E 5LMNI 2E1RA 3JAMQ 1XHKA 2AJ4A 4X64E 4DR1I 4LCHA 4MU0A 1PIEA 4LF9I 1XNRI 4ISAA 5K36D 4NXNE 4JI6E 1RREA 2VQFE 5C0XA 1XNQI 4FW6A 4JI0I 4OX9I 2NPFA 3B4TA 1H7UA 2HK2A 4DR2E 1B62A 5DNXA 4GKKI 1ZM4A 3B8HA 4DR5I 2UXCE 4KHPE 5K36A 1UDQA 3M85D 1YHCA 2EFGA 4JYAI 1XMQE 3P3CA 4XTJA 5C0XF 2UUBE 3WU3A 2NN6D 3ZZTA 5A2QQ 2F4VE 1I94I 4DUZE 4DV2I 1HR0E 3KRNA 3HULA 5C0XE 3QT6A 1UDOA 1WUUA 1H7SA 2C38A 4X65E 4N3OA 4PRVA 1J5EI 4YHHI 5K36F 5JEAA 2PO0A 2O1TA 2NN6A 3PYFA 2IERA 1PVGA 4LF8E 1R6LA 4BA1B 4JI5E 4AIMA 4DPTA 2BA1G 2C39A 4GKJI 4JV5E 4DV3I 2Z5BA 1HNWI 1N32E 1A6FA 4LPFA 4BA2A 1USVA 2PO1B 3P3GA 4FW9A 5JEAF 4FWGA 4P52A 3T1YI 2NN6F 1OYPA 2J7KA 4B3TI 2UXDI 2JEAA 2HFUA 5DRPA 3QT5A 5LMNE 3PYEA 4DR1E 1IBME 1Y4SA 4FW4A 4LF9E 1XNRE 1KIJA 2PO2A 2JE6A 1XNQE 4JI0E 4OX9E 4DR6I 1E3PA 3P06A 3WU6A 2GS8A 3GCMA 3M7NG 2VESA 2ZITA 2V2ZA 4WUCA 4JI8I 4DR7I 5EL9A 3CDIA 1Z0WA 2J65A 4LF6I 4DPXA 4GKKE 1OYSA 1Z5AA 2R3VA 4JYAE 1OYRA 2BA0D 2X36A 3WU4A 4MDTA 2ZM6I 2Z5CA 4DR4I 3J7AG 3J81Q 4PRXA 2BR2A 1HNXI 4NXMI 4U3BA 4B3MI 3LTOA 4OO1E 4WUBA 2CZ9A 3QT7A 4B3RI 1N0VC 1I94E 4P7AA 3J80Q 4MYUA 1Y60A 4HY1A 1NHJA 4DV0I 2Q2EB 1RHYA 4JG4A 4UTGA 1J5EE 4YHHE 3QT8A 1MG7A 4DV4I 3P76A 4X66I 5LL6R 3P3EA 1UEKA 4JI2E 2A2DA 1FNMA 5IT9Q 1VI7A 1B63A 3K17A 4DV5I 4DPUA 2A2CA 1HNWE 4DV3E 2CVEA 3H1CA 1KVKA 4RPFA 5JEAB 5LMUI 2PO0B 4MQYA 3GLLA 2PNZA 4X62I 4OO1C 2NN6B 4JI4I 1Z0GA 1P42A 4LF4I 4B3TE 2C37B 4QNJA 2UXDE 1R6MA 5IWAI 3OTOI 4IFDE 2DEJA 4USMA 4URLA 2C39B 2Z5BB 4BA2B 3CWVA 1Y6ZA 5GMDA 2HK3A 4DXLA 2BM0A 3PS3A 4M1KA 1FWLA 4DR6E 1XMOI 1HNZI 1RR9A 2GO4A 5FLXQ 1FWKA 1KKHA 1N34I 4FN5A 1S4EA 5ELWA 4DV1I 2JEAB 1PKPA 4JI8E 4DR7E 4LF6E 4DU7A 2VQEI 2V2QA 4MYTA 1EI1A 5BR8E 2CG9A 3NZKA 4GQUA 4AM3A 2PO2B 1DARA 2GO3A 2JE6B 1IBLI 4JI7I 4LFBE 4OO1D 1HNXE 2XEXA 1H73A 4NXME 1ELOA 4JI1I
chains in the Genus database with same CATH topology
4J3DA 4FW5A 3PS1A 2VESA 4LCFA 4MQYA 2JT2A 2GO4A 4OKGA 3U1YA 5DROA 4FW7A 1YHCA 2J65A 1XXEA 3P3CA 3P76A 5DRPA 4LCHA 4LCGA 3P3EA 1P42A 1YH8A 5DRRA 5DRQA 2IERA 4U3DA 4ISAA 3UHMA 4MDTA 4OZEA 4FW3A 2O3ZA 4FW6A 4FW4A 4IS9A 3NZKA 2IESA 3PS2A 2GO3A 4U3BA 3P3GA 3PS3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J3D A;  4FW5 A;  3PS1 A;  2VES A;  4LCF A;  4MQY A;  2JT2 A;  2GO4 A;  4OKG A;  3U1Y A;  5DRO A;  4FW7 A;  1YHC A;  2J65 A;  1XXE A;  3P3C A;  3P76 A;  5DRP A;  4LCH A;  4LCG A;  3P3E A;  1P42 A;  1YH8 A;  5DRR A;  5DRQ A;  2IER A;  4U3D A;  4ISA A;  3UHM A;  4MDT A;  4OZE A;  4FW3 A;  2O3Z A;  4FW6 A;  4FW4 A;  4IS9 A;  3NZK A;  2IES A;  3PS2 A;  2GO3 A;  4U3B A;  3P3G A;  3PS3 A; 
#chains in the Genus database with same CATH topology
 4B3M E;  1N33 E;  4IZK A;  4IFD C;  4DV7 I;  4B3R E;  2V2V A;  2OI2 A;  4JI6 I;  1BKN A;  3ZZU A;  1Z5C A;  4DV0 E;  4LFA I;  3D4J A;  4DPY A;  2UUC I;  1FI4 A;  4DV6 I;  5FWK A;  4DV4 E;  2HHH I;  2Z5C B;  1Z0T A;  4OO1 A;  4X66 E;  4IS9 A;  1K47 A;  4HAC B;  1MU5 A;  3LPS A;  4AQY I;  2F1D A;  3GON A;  2JEB A;  4QNK A;  4KHP I;  1Z0V A;  1ZM2 A;  4FW5 A;  2BM1 A;  3PS1 A;  4USK A;  1VIS A;  4DPW A;  1Z59 A;  2HFS A;  3U1Y A;  4PU9 A;  1HK7 A;  1OJ4 A;  3Q6M A;  3J80 C;  3J7A M;  2WP8 A;  3H4L A;  4R1F A;  2HKE A;  3K1J A;  1KTV A;  4DR5 E;  4OO1 F;  4JI4 E;  4OZE A;  1Z0C A;  1IBK I;  5C0X B;  1FKA E;  3JAM C;  4LF4 E;  4X65 I;  4IFD D;  3M85 G;  4LF5 I;  3Q6N A;  3OTO E;  4JI3 I;  1E3H A;  4B3S I;  4DV2 E;  1UDS A;  3L7Z A;  4DR3 I;  2JT2 A;  4OKG A;  2BA1 D;  3ZKD A;  5K36 B;  1XMO E;  4IFD A;  4FWD A;  4LCG A;  1YH8 A;  4JV5 I;  3U1K A;  1NHI A;  3UHM A;  3V2U C;  4DV1 E;  2UU9 I;  1FJG I;  4YY3 I;  4IZJ D;  2UUA I;  3PS2 A;  4DU8 A;  2VQE E;  1ZM9 A;  4MU4 A;  2O1W A;  1D6T A;  4GKJ E;  2C38 B;  5A2Q C;  1IBL E;  4J3D A;  3LNU A;  4LFC I;  3ZZ0 A;  1ZM3 A;  3T1H I;  4LCF A;  4JI1 E;  2IOQ A;  4WUD A;  3Q1Q A;  4IFD F;  5GME A;  4FW7 A;  4DV7 E;  4MU1 A;  4EMD A;  3T1Y E;  1IBM I;  1Z5B A;  4IZJ A;  5DRQ A;  2HKJ A;  1EA6 A;  5FLX C;  4LFA E;  2UUC E;  3M7N D;  4DV6 E;  2HHH E;  1H74 A;  4HXZ A;  1Y5Y A;  3B82 A;  2E5L I;  2WNR A;  2PNL A;  4IZK B;  4AQY E;  1N0U A;  5L3J A;  2ZBK B;  2CGE A;  1S16 A;  5JEA D;  2PNM A;  1XXE A;  4K0K I;  1MX0 A;  2V8P A;  3PYD A;  2WW4 A;  4OO1 B;  4DUY I;  2O3Z A;  2LJP A;  2UXB I;  1N36 I;  1ZXN A;  1IBK E;  2ZM6 E;  2JEB B;  2BV3 A;  4DR4 E;  2VF3 A;  4LF5 E;  1Y4U A;  2BA0 G;  4LF7 I;  3PRY A;  4JI3 E;  4X64 I;  4B3S E;  4AID A;  4JI2 I;  2X7I A;  3HJC A;  4NXN I;  2WP8 B;  3B78 A;  1QZR A;  2VQF I;  4DR3 E;  3ZM7 A;  2C37 A;  5K36 E;  1Z0B A;  4U3D A;  1H72 C;  4FWH A;  4DR2 I;  4FW3 A;  2GQ0 A;  2V34 A;  4MU3 A;  2BR2 B;  3GME A;  3K85 A;  4Z7C A;  2UU9 E;  3WU5 A;  1FJG E;  4YY3 E;  2UUA E;  4DV5 E;  5EKW A;  2UXC I;  2DEI A;  4NBQ A;  3J81 C;  2IOP A;  3HKM A;  3L7Z B;  1XMQ I;  4ZVI A;  4UT4 A;  2UUB I;  5C0X C;  3T1H E;  4LFC E;  1UDN A;  5JEA E;  5LMU E;  4IFD B;  2O1U A;  2F4V I;  4X62 E;  4DUZ I;  5DNL A;  2NN6 E;  1USU A;  1HR0 I;  4LOM A;  4BA1 A;  2IES A;  3CDJ A;  3DD6 A;  2O1V A;  5IWA E;  2PO1 A;  2R42 A;  5IT9 C;  5K36 C;  4I3H A;  3PYG A;  2AE8 A;  2E5L E;  2PNZ B;  4Z7Y A;  5DRO A;  4LF8 I;  1U2R A;  4KQV A;  4IZJ B;  2Z5E A;  1HNZ E;  5DRR A;  5BR8 I;  4JI5 I;  1NZ0 A;  1NHH A;  3M6A A;  1N34 E;  1N32 I;  4LFB I;  4K0K E;  4HYM A;  1ZXM A;  4HAC A;  3ZKB A;  3F0N A;  1N33 I;  3V5R A;  5JEA C;  4ED4 A;  5C0X D;  4DUY E;  1Z0E A;  2UXB E;  2WNR B;  1N36 E;  2NN6 C;  4JI7 E;  4LF7 E;  5LMN I;  2E1R A;  3JAM Q;  1XHK A;  2AJ4 A;  4X64 E;  4DR1 I;  4LCH A;  4MU0 A;  1PIE A;  4LF9 I;  1XNR I;  4ISA A;  5K36 D;  4NXN E;  4JI6 E;  1RRE A;  2VQF E;  5C0X A;  1XNQ I;  4FW6 A;  4JI0 I;  4OX9 I;  2NPF A;  3B4T A;  1H7U A;  2HK2 A;  4DR2 E;  1B62 A;  5DNX A;  4GKK I;  1ZM4 A;  3B8H A;  4DR5 I;  2UXC E;  4KHP E;  5K36 A;  1UDQ A;  3M85 D;  1YHC A;  2EFG A;  4JYA I;  1XMQ E;  3P3C A;  4XTJ A;  5C0X F;  2UUB E;  3WU3 A;  2NN6 D;  3ZZT A;  5A2Q Q;  2F4V E;  1I94 I;  4DUZ E;  4DV2 I;  1HR0 E;  3KRN A;  3HUL A;  5C0X E;  3QT6 A;  1UDO A;  1WUU A;  1H7S A;  2C38 A;  4X65 E;  4N3O A;  4PRV A;  1J5E I;  4YHH I;  5K36 F;  5JEA A;  2PO0 A;  2O1T A;  2NN6 A;  3PYF A;  2IER A;  1PVG A;  4LF8 E;  1R6L A;  4BA1 B;  4JI5 E;  4AIM A;  4DPT A;  2BA1 G;  2C39 A;  4GKJ I;  4JV5 E;  4DV3 I;  2Z5B A;  1HNW I;  1N32 E;  1A6F A;  4LPF A;  4BA2 A;  1USV A;  2PO1 B;  3P3G A;  4FW9 A;  5JEA F;  4FWG A;  4P52 A;  3T1Y I;  2NN6 F;  1OYP A;  2J7K A;  4B3T I;  2UXD I;  2JEA A;  2HFU A;  5DRP A;  3QT5 A;  5LMN E;  3PYE A;  4DR1 E;  1IBM E;  1Y4S A;  4FW4 A;  4LF9 E;  1XNR E;  1KIJ A;  2PO2 A;  2JE6 A;  1XNQ E;  4JI0 E;  4OX9 E;  4DR6 I;  1E3P A;  3P06 A;  3WU6 A;  2GS8 A;  3GCM A;  3M7N G;  2VES A;  2ZIT A;  2V2Z A;  4WUC A;  4JI8 I;  4DR7 I;  5EL9 A;  3CDI A;  1Z0W A;  2J65 A;  4LF6 I;  4DPX A;  4GKK E;  1OYS A;  1Z5A A;  2R3V A;  4JYA E;  1OYR A;  2BA0 D;  2X36 A;  3WU4 A;  4MDT A;  2ZM6 I;  2Z5C A;  4DR4 I;  3J7A G;  3J81 Q;  4PRX A;  2BR2 A;  1HNX I;  4NXM I;  4U3B A;  4B3M I;  3LTO A;  4OO1 E;  4WUB A;  2CZ9 A;  3QT7 A;  4B3R I;  1N0V C;  1I94 E;  4P7A A;  3J80 Q;  4MYU A;  1Y60 A;  4HY1 A;  1NHJ A;  4DV0 I;  2Q2E B;  1RHY A;  4JG4 A;  4UTG A;  1J5E E;  4YHH E;  3QT8 A;  1MG7 A;  4DV4 I;  3P76 A;  4X66 I;  5LL6 R;  3P3E A;  1UEK A;  4JI2 E;  2A2D A;  1FNM A;  5IT9 Q;  1VI7 A;  1B63 A;  3K17 A;  4DV5 I;  4DPU A;  2A2C A;  1HNW E;  4DV3 E;  2CVE A;  3H1C A;  1KVK A;  4RPF A;  5JEA B;  5LMU I;  2PO0 B;  4MQY A;  3GLL A;  2PNZ A;  4X62 I;  4OO1 C;  2NN6 B;  4JI4 I;  1Z0G A;  1P42 A;  4LF4 I;  4B3T E;  2C37 B;  4QNJ A;  2UXD E;  1R6M A;  5IWA I;  3OTO I;  4IFD E;  2DEJ A;  4USM A;  4URL A;  2C39 B;  2Z5B B;  4BA2 B;  3CWV A;  1Y6Z A;  5GMD A;  2HK3 A;  4DXL A;  2BM0 A;  3PS3 A;  4M1K A;  1FWL A;  4DR6 E;  1XMO I;  1HNZ I;  1RR9 A;  2GO4 A;  5FLX Q;  1FWK A;  1KKH A;  1N34 I;  4FN5 A;  1S4E A;  5ELW A;  4DV1 I;  2JEA B;  1PKP A;  4JI8 E;  4DR7 E;  4LF6 E;  4DU7 A;  2VQE I;  2V2Q A;  4MYT A;  1EI1 A;  5BR8 E;  2CG9 A;  3NZK A;  4GQU A;  4AM3 A;  2PO2 B;  1DAR A;  2GO3 A;  2JE6 B;  1IBL I;  4JI7 I;  4LFB E;  4OO1 D;  1HNX E;  2XEX A;  1H73 A;  4NXM E;  1ELO A;  4JI1 I; 
#chains in the Genus database with same CATH homology
 4J3D A;  4FW5 A;  3PS1 A;  2VES A;  4LCF A;  4MQY A;  2JT2 A;  2GO4 A;  4OKG A;  3U1Y A;  5DRO A;  4FW7 A;  1YHC A;  2J65 A;  1XXE A;  3P3C A;  3P76 A;  5DRP A;  4LCH A;  4LCG A;  3P3E A;  1P42 A;  1YH8 A;  5DRR A;  5DRQ A;  2IER A;  4U3D A;  4ISA A;  3UHM A;  4MDT A;  4OZE A;  4FW3 A;  2O3Z A;  4FW6 A;  4FW4 A;  4IS9 A;  3NZK A;  2IES A;  3PS2 A;  2GO3 A;  4U3B A;  3P3G A;  3PS3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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