2GOOB

Ternary complex of bmp-2 bound to bmpr-ia-ecd and actrii-ecd
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
85
structure length
85
Chain Sequence
PFLKCYCSGHCPDDAINNTCITNGHCFAIIEEDDQGETTLASGCMKYEGSDFQCKDSPKAQLRRTIECCRTNLCNQYLQPTLPPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the ternary signaling complex of a TGF-beta superfamily member.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Bone morphogenetic protein 2
total genus 15
structure length 85
sequence length 85
chains with identical sequence E
ec nomenclature ec 2.7.11.30: Receptor protein serine/threonine kinase.
pdb deposition date 2006-04-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01064 Activin_recp Activin types I and II receptor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 2gooB00
1LXGA 1RGJA 2L03A 1CTXA 1LJZA 1CHVS 4OM4A 1JBDA 4IYEA 5DO6A 1S4YA 1TXBA 5EBXA 2QJAC 2CRSA 1FSSB 2MJ4A 1MR6A 2H7ZB 1VB0A 1BXPA 1CXOA 1KS6A 1LXHA 3FEVA 1UG4A 1KFHA 1IDGA 1KBSA 4BIKB 2HLRA 1TFSA 1HAJA 1FSCA 1CB9A 1CRFA 2L5SA 1REWC 2HLQA 3LAQU 1HOYA 2PJYB 1IDIA 2GOOB 1KU6B 3U74U 1DRSA 3NEQA 1M9ZA 2H7ZA 6EBXA 1IDHA 2H5FA 1CREA 1HC9B 5IMTD 1CDSA 2I9BE 2X8BB 2JVEA 1LX5B 2MUOA 1B41B 1JE9A 4AEAA 2VLWA 1NYUA 1PLOA 2OFSA 1CODA 2MFAA 1KBTA 1NTNA 1BTEA 5DU1A 1FASA 1TGXA 1NXBA 1ERAA 2ERAA 1CDRA 1QKDA 2N99A 4FAOE 1F8UB 2ABXA 3BT1U 1HC9A 1RL5A 4LFTA 2K3GA 1KTZB 4UY2C 1IK8A 1QKEA 3NH7A 1MAHF 1ONJA 3NDSA 1ERGA 1L4WA 3KFDI 4EY8B 2LCRA 1NTXA 1TXAA 3KFDE 1G6MA 4XJJA 1F94A 2NBTA 4DO8A 2PJYC 1IKCA 1FRAA 2CTXA 2QC1A 3EBXA 3PLCA 1IQ9A 1HAAA 1NYSA 1NORA 1KBAA 2LA1A 1CDTA 1CVOA 4P7UA 1COEA 2MJYA 2H64B 1KXIA 1H0JA 5DZ5A 4FAOC 1IJCA 1LSIA 4OM5A 2BTXA 2UX2A 2H62D 3EVSC 4BDTB 1V6PA 1I02A 1KL8A 1KC4A 2MJ0A 2CRTA 2MHYA 2FD6U 2H8UA 3BT2U 1ABTA 1CXNA 2J8BA 2UWRA 4ZQYA 1CCQA 1CDQA 3ERAA 2GOOC 3QB4B 2H62C 4RUDA 2JQPA 1ES7B 1FF4A 2MUPA 3HH7A 3U73U 1IDLA 2CCXA 2QJ9C 4QTIU 1YWHA 4HQPF 5IMYC 1FFJA 2BHIA 1W6BA 1ZADA 1QM7A 2QJBC 1XT3A 2H64C 3VTSA 1NEAA 1JGKA 2CDXA
chains in the Genus database with same CATH superfamily
1LXGA 1RGJA 2L03A 1CTXA 1LJZA 1CHVS 4OM4A 1JBDA 4IYEA 5DO6A 1S4YA 1TXBA 5EBXA 2QJAC 2CRSA 1FSSB 2MJ4A 1MR6A 2H7ZB 1VB0A 1BXPA 1CXOA 1KS6A 1LXHA 3FEVA 1UG4A 1KFHA 1IDGA 1KBSA 4BIKB 2HLRA 1TFSA 1HAJA 1FSCA 1CB9A 1CRFA 2L5SA 1REWC 2HLQA 3LAQU 1HOYA 2PJYB 1IDIA 2GOOB 1KU6B 3U74U 1DRSA 3NEQA 1M9ZA 2H7ZA 6EBXA 1IDHA 2H5FA 1CREA 1HC9B 5IMTD 1CDSA 2I9BE 2X8BB 2JVEA 1LX5B 2MUOA 1B41B 1JE9A 4AEAA 2VLWA 1NYUA 1PLOA 2OFSA 1CODA 2MFAA 1KBTA 1NTNA 1BTEA 5DU1A 1FASA 1TGXA 1NXBA 1ERAA 2ERAA 1CDRA 1QKDA 2N99A 4KSNA 4FAOE 1F8UB 2ABXA 3BT1U 1HC9A 1RL5A 4LFTA 2K3GA 1KTZB 4UY2C 1IK8A 1QKEA 3NH7A 1MAHF 1ONJA 3NDSA 1ERGA 1L4WA 3KFDI 4EY8B 2LCRA 1NTXA 1TXAA 3KFDE 1G6MA 4XJJA 1F94A 2NBTA 4DO8A 2PJYC 1IKCA 1FRAA 2CTXA 2QC1A 3EBXA 3PLCA 1IQ9A 1HAAA 1NYSA 1NORA 1KBAA 2LA1A 1CDTA 1CVOA 4P7UA 1COEA 2MJYA 2H64B 1KXIA 1H0JA 5DZ5A 4FAOC 1IJCA 1LSIA 4OM5A 2BTXA 2UX2A 2H62D 3EVSC 4BDTB 1V6PA 1I02A 1KL8A 1KC4A 2MJ0A 2CRTA 2MHYA 2FD6U 2H8UA 3BT2U 1ABTA 1CXNA 2J8BA 2UWRA 4ZQYA 1CCQA 1CDQA 3ERAA 2GOOC 3QB4B 2H62C 4RUDA 2JQPA 1ES7B 1FF4A 2MUPA 3HH7A 3U73U 1IDLA 2CCXA 2QJ9C 4QTIU 1YWHA 4HQPF 5IMYC 1FFJA 2BHIA 1W6BA 1ZADA 1QM7A 2QJBC 1XT3A 2H64C 3VTSA 1NEAA 1JGKA 2CDXA
chains in the Genus database with same CATH topology
1LXGA 1RGJA 2L03A 1CTXA 1LJZA 1CHVS 4OM4A 1JBDA 4IYEA 5DO6A 1S4YA 1TXBA 5EBXA 2QJAC 2CRSA 1FSSB 2MJ4A 1MR6A 2H7ZB 1VB0A 1BXPA 1CXOA 1KS6A 1LXHA 3FEVA 1UG4A 1KFHA 1IDGA 1KBSA 4BIKB 2HLRA 1TFSA 1HAJA 1FSCA 1CB9A 1CRFA 2L5SA 1REWC 2HLQA 3LAQU 1HOYA 2PJYB 1IDIA 2GOOB 1KU6B 3U74U 1DRSA 3NEQA 1M9ZA 2H7ZA 6EBXA 1IDHA 2H5FA 1CREA 1HC9B 5IMTD 1CDSA 2I9BE 2X8BB 2JVEA 1LX5B 2MUOA 1B41B 1JE9A 4AEAA 2VLWA 1NYUA 1PLOA 2OFSA 1CODA 2MFAA 1KBTA 1NTNA 1BTEA 5DU1A 1FASA 1TGXA 1NXBA 1ERAA 2ERAA 1CDRA 1QKDA 2N99A 4KSNA 4FAOE 1F8UB 2ABXA 3BT1U 1HC9A 1RL5A 4LFTA 2K3GA 1KTZB 4UY2C 1IK8A 1QKEA 3NH7A 1MAHF 1ONJA 3NDSA 1ERGA 1L4WA 3KFDI 4EY8B 2LCRA 1NTXA 1TXAA 3KFDE 1G6MA 4XJJA 1F94A 2NBTA 4DO8A 2PJYC 1IKCA 1FRAA 2CTXA 2QC1A 3EBXA 3PLCA 1IQ9A 1HAAA 1NYSA 1NORA 1KBAA 2LA1A 1CDTA 1CVOA 4P7UA 1COEA 2MJYA 2H64B 1KXIA 1H0JA 5DZ5A 4FAOC 1IJCA 1LSIA 4OM5A 2BTXA 2UX2A 2H62D 3EVSC 4BDTB 1V6PA 1I02A 1KL8A 1KC4A 2MJ0A 2CRTA 2MHYA 2FD6U 2H8UA 3BT2U 1ABTA 1CXNA 2J8BA 2UWRA 4ZQYA 1CCQA 1CDQA 3ERAA 2GOOC 3QB4B 2H62C 4RUDA 2JQPA 1ES7B 1FF4A 2MUPA 3HH7A 3U73U 1IDLA 2CCXA 2QJ9C 4QTIU 1YWHA 4HQPF 5IMYC 1FFJA 2BHIA 1W6BA 1ZADA 1QM7A 2QJBC 1XT3A 2H64C 3VTSA 1NEAA 1JGKA 2CDXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LXG A;  1RGJ A;  2L03 A;  1CTX A;  1LJZ A;  1CHV S;  4OM4 A;  1JBD A;  4IYE A;  5DO6 A;  1S4Y A;  1TXB A;  5EBX A;  2QJA C;  2CRS A;  1FSS B;  2MJ4 A;  1MR6 A;  2H7Z B;  1VB0 A;  1BXP A;  1CXO A;  1KS6 A;  1LXH A;  3FEV A;  1UG4 A;  1KFH A;  1IDG A;  1KBS A;  4BIK B;  2HLR A;  1TFS A;  1HAJ A;  1FSC A;  1CB9 A;  1CRF A;  2L5S A;  1REW C;  2HLQ A;  3LAQ U;  1HOY A;  2PJY B;  1IDI A;  2GOO B;  1KU6 B;  3U74 U;  1DRS A;  3NEQ A;  1M9Z A;  2H7Z A;  6EBX A;  1IDH A;  2H5F A;  1CRE A;  1HC9 B;  5IMT D;  1CDS A;  2I9B E;  2X8B B;  2JVE A;  1LX5 B;  2MUO A;  1B41 B;  1JE9 A;  4AEA A;  2VLW A;  1NYU A;  1PLO A;  2OFS A;  1COD A;  2MFA A;  1KBT A;  1NTN A;  1BTE A;  5DU1 A;  1FAS A;  1TGX A;  1NXB A;  1ERA A;  2ERA A;  1CDR A;  1QKD A;  2N99 A;  4FAO E;  1F8U B;  2ABX A;  3BT1 U;  1HC9 A;  1RL5 A;  4LFT A;  2K3G A;  1KTZ B;  4UY2 C;  1IK8 A;  1QKE A;  3NH7 A;  1MAH F;  1ONJ A;  3NDS A;  1ERG A;  1L4W A;  3KFD I;  4EY8 B;  2LCR A;  1NTX A;  1TXA A;  3KFD E;  1G6M A;  4XJJ A;  1F94 A;  2NBT A;  4DO8 A;  2PJY C;  1IKC A;  1FRA A;  2CTX A;  2QC1 A;  3EBX A;  3PLC A;  1IQ9 A;  1HAA A;  1NYS A;  1NOR A;  1KBA A;  2LA1 A;  1CDT A;  1CVO A;  4P7U A;  1COE A;  2MJY A;  2H64 B;  1KXI A;  1H0J A;  5DZ5 A;  4FAO C;  1IJC A;  1LSI A;  4OM5 A;  2BTX A;  2UX2 A;  2H62 D;  3EVS C;  4BDT B;  1V6P A;  1I02 A;  1KL8 A;  1KC4 A;  2MJ0 A;  2CRT A;  2MHY A;  2FD6 U;  2H8U A;  3BT2 U;  1ABT A;  1CXN A;  2J8B A;  2UWR A;  4ZQY A;  1CCQ A;  1CDQ A;  3ERA A;  2GOO C;  3QB4 B;  2H62 C;  4RUD A;  2JQP A;  1ES7 B;  1FF4 A;  2MUP A;  3HH7 A;  3U73 U;  1IDL A;  2CCX A;  2QJ9 C;  4QTI U;  1YWH A;  4HQP F;  5IMY C;  1FFJ A;  2BHI A;  1W6B A;  1ZAD A;  1QM7 A;  2QJB C;  1XT3 A;  2H64 C;  3VTS A;  1NEA A;  1JGK A;  2CDX A; 
#chains in the Genus database with same CATH topology
 1LXG A;  1RGJ A;  2L03 A;  1CTX A;  1LJZ A;  1CHV S;  4OM4 A;  1JBD A;  4IYE A;  5DO6 A;  1S4Y A;  1TXB A;  5EBX A;  2QJA C;  2CRS A;  1FSS B;  2MJ4 A;  1MR6 A;  2H7Z B;  1VB0 A;  1BXP A;  1CXO A;  1KS6 A;  1LXH A;  3FEV A;  1UG4 A;  1KFH A;  1IDG A;  1KBS A;  4BIK B;  2HLR A;  1TFS A;  1HAJ A;  1FSC A;  1CB9 A;  1CRF A;  2L5S A;  1REW C;  2HLQ A;  3LAQ U;  1HOY A;  2PJY B;  1IDI A;  2GOO B;  1KU6 B;  3U74 U;  1DRS A;  3NEQ A;  1M9Z A;  2H7Z A;  6EBX A;  1IDH A;  2H5F A;  1CRE A;  1HC9 B;  5IMT D;  1CDS A;  2I9B E;  2X8B B;  2JVE A;  1LX5 B;  2MUO A;  1B41 B;  1JE9 A;  4AEA A;  2VLW A;  1NYU A;  1PLO A;  2OFS A;  1COD A;  2MFA A;  1KBT A;  1NTN A;  1BTE A;  5DU1 A;  1FAS A;  1TGX A;  1NXB A;  1ERA A;  2ERA A;  1CDR A;  1QKD A;  2N99 A;  4KSN A;  4FAO E;  1F8U B;  2ABX A;  3BT1 U;  1HC9 A;  1RL5 A;  4LFT A;  2K3G A;  1KTZ B;  4UY2 C;  1IK8 A;  1QKE A;  3NH7 A;  1MAH F;  1ONJ A;  3NDS A;  1ERG A;  1L4W A;  3KFD I;  4EY8 B;  2LCR A;  1NTX A;  1TXA A;  3KFD E;  1G6M A;  4XJJ A;  1F94 A;  2NBT A;  4DO8 A;  2PJY C;  1IKC A;  1FRA A;  2CTX A;  2QC1 A;  3EBX A;  3PLC A;  1IQ9 A;  1HAA A;  1NYS A;  1NOR A;  1KBA A;  2LA1 A;  1CDT A;  1CVO A;  4P7U A;  1COE A;  2MJY A;  2H64 B;  1KXI A;  1H0J A;  5DZ5 A;  4FAO C;  1IJC A;  1LSI A;  4OM5 A;  2BTX A;  2UX2 A;  2H62 D;  3EVS C;  4BDT B;  1V6P A;  1I02 A;  1KL8 A;  1KC4 A;  2MJ0 A;  2CRT A;  2MHY A;  2FD6 U;  2H8U A;  3BT2 U;  1ABT A;  1CXN A;  2J8B A;  2UWR A;  4ZQY A;  1CCQ A;  1CDQ A;  3ERA A;  2GOO C;  3QB4 B;  2H62 C;  4RUD A;  2JQP A;  1ES7 B;  1FF4 A;  2MUP A;  3HH7 A;  3U73 U;  1IDL A;  2CCX A;  2QJ9 C;  4QTI U;  1YWH A;  4HQP F;  5IMY C;  1FFJ A;  2BHI A;  1W6B A;  1ZAD A;  1QM7 A;  2QJB C;  1XT3 A;  2H64 C;  3VTS A;  1NEA A;  1JGK A;  2CDX A; 
#chains in the Genus database with same CATH homology
 1LXG A;  1RGJ A;  2L03 A;  1CTX A;  1LJZ A;  1CHV S;  4OM4 A;  1JBD A;  4IYE A;  5DO6 A;  1S4Y A;  1TXB A;  5EBX A;  2QJA C;  2CRS A;  1FSS B;  2MJ4 A;  1MR6 A;  2H7Z B;  1VB0 A;  1BXP A;  1CXO A;  1KS6 A;  1LXH A;  3FEV A;  1UG4 A;  1KFH A;  1IDG A;  1KBS A;  4BIK B;  2HLR A;  1TFS A;  1HAJ A;  1FSC A;  1CB9 A;  1CRF A;  2L5S A;  1REW C;  2HLQ A;  3LAQ U;  1HOY A;  2PJY B;  1IDI A;  2GOO B;  1KU6 B;  3U74 U;  1DRS A;  3NEQ A;  1M9Z A;  2H7Z A;  6EBX A;  1IDH A;  2H5F A;  1CRE A;  1HC9 B;  5IMT D;  1CDS A;  2I9B E;  2X8B B;  2JVE A;  1LX5 B;  2MUO A;  1B41 B;  1JE9 A;  4AEA A;  2VLW A;  1NYU A;  1PLO A;  2OFS A;  1COD A;  2MFA A;  1KBT A;  1NTN A;  1BTE A;  5DU1 A;  1FAS A;  1TGX A;  1NXB A;  1ERA A;  2ERA A;  1CDR A;  1QKD A;  2N99 A;  4KSN A;  4FAO E;  1F8U B;  2ABX A;  3BT1 U;  1HC9 A;  1RL5 A;  4LFT A;  2K3G A;  1KTZ B;  4UY2 C;  1IK8 A;  1QKE A;  3NH7 A;  1MAH F;  1ONJ A;  3NDS A;  1ERG A;  1L4W A;  3KFD I;  4EY8 B;  2LCR A;  1NTX A;  1TXA A;  3KFD E;  1G6M A;  4XJJ A;  1F94 A;  2NBT A;  4DO8 A;  2PJY C;  1IKC A;  1FRA A;  2CTX A;  2QC1 A;  3EBX A;  3PLC A;  1IQ9 A;  1HAA A;  1NYS A;  1NOR A;  1KBA A;  2LA1 A;  1CDT A;  1CVO A;  4P7U A;  1COE A;  2MJY A;  2H64 B;  1KXI A;  1H0J A;  5DZ5 A;  4FAO C;  1IJC A;  1LSI A;  4OM5 A;  2BTX A;  2UX2 A;  2H62 D;  3EVS C;  4BDT B;  1V6P A;  1I02 A;  1KL8 A;  1KC4 A;  2MJ0 A;  2CRT A;  2MHY A;  2FD6 U;  2H8U A;  3BT2 U;  1ABT A;  1CXN A;  2J8B A;  2UWR A;  4ZQY A;  1CCQ A;  1CDQ A;  3ERA A;  2GOO C;  3QB4 B;  2H62 C;  4RUD A;  2JQP A;  1ES7 B;  1FF4 A;  2MUP A;  3HH7 A;  3U73 U;  1IDL A;  2CCX A;  2QJ9 C;  4QTI U;  1YWH A;  4HQP F;  5IMY C;  1FFJ A;  2BHI A;  1W6B A;  1ZAD A;  1QM7 A;  2QJB C;  1XT3 A;  2H64 C;  3VTS A;  1NEA A;  1JGK A;  2CDX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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