2GTPC

Crystal structure of the heterodimeric complex of human rgs1 and activated gi alpha 1
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
132
structure length
132
Chain Sequence
VLSAAEVMQWSQSLEKLLANQTGQNVFGSFLKSEFSEENIEFWLACEDYKKTESDLLPCKAEEIYKAFVHSDAAKQINIDFRTRESTAKKIKAPTPTCFDEAQKVIYTLMEKDSYPRFLKSDIYLNLLNDLQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Guanine nucleotide-binding protein G(i), alpha-1 subunit
publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
source organism Homo sapiens
total genus 46
structure length 132
sequence length 132
chains with identical sequence D
ec nomenclature
pdb deposition date 2006-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2gtpC02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2gtpC01
2JM5A 2CRPA 1EZYA 3C7LA 3KRXA 2AF0A 1OMWA 5HE2A 3C7KB 4TNDA 3UZTA 2BCJA 2BT2A 2IHBB 2GTPC 1AGRE 1CMZA 1FQKB 2DLVA 2IHDA 3V5WA 3NYNA 2OWIA 3NYOA 1DK8A 4PNKA 1EMUA 4EKDB 4MK0A 4TNBA 3PVWA 2EBZA 3PSCA 5HE1A 2BV1A 5HE0A 2D9JA 3KRWA 3PVUA 2JNUA 2OJ4A 2V4ZB 2IK8B 5HE3A 1FQJB 2ODEB 3CIKA 1EZTA 1FQIA 5DO9B
chains in the Genus database with same CATH superfamily
2JM5A 2CRPA 1EZYA 3C7LA 3KRXA 2AF0A 1OMWA 5HE2A 3C7KB 4TNDA 3UZTA 2BCJA 2BT2A 2IHBB 2GTPC 1AGRE 1CMZA 1FQKB 2DLVA 2IHDA 3I5QA 3V5WA 3NYNA 2OWIA 3NYOA 1DK8A 4PNKA 1EMUA 4EKDB 4MK0A 4HTEA 4TNBA 5REQB 3PVWA 2EBZA 3PSCA 5HE1A 2BV1A 5HE0A 2D9JA 3KRWA 3PVUA 2JNUA 2OJ4A 2V4ZB 2IK8B 5HE3A 1FQJB 2ODEB 3CIKA 1EZTA 3QYFA 1FQIA 5DO9B
chains in the Genus database with same CATH topology
2JM5A 2CRPA 1EZYA 3C7LA 3KRXA 2AF0A 1OMWA 5HE2A 3C7KB 4TNDA 3UZTA 2BCJA 2BT2A 2IHBB 2GTPC 1AGRE 1CMZA 1FQKB 2DLVA 2IHDA 3V5WA 3NYNA 2OWIA 3NYOA 1DK8A 4PNKA 1EMUA 4EKDB 4MK0A 4TNBA 5REQB 3PVWA 2EBZA 3PSCA 5HE1A 2BV1A 5HE0A 2D9JA 3KRWA 3PVUA 2JNUA 2OJ4A 2V4ZB 2IK8B 5HE3A 1FQJB 2ODEB 3CIKA 1EZTA 3QYFA 1FQIA 5DO9B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JM5 A;  2CRP A;  1EZY A;  3C7L A;  3KRX A;  2AF0 A;  1OMW A;  5HE2 A;  3C7K B;  4TND A;  3UZT A;  2BCJ A;  2BT2 A;  2IHB B;  2GTP C;  1AGR E;  1CMZ A;  1FQK B;  2DLV A;  2IHD A;  3V5W A;  3NYN A;  2OWI A;  3NYO A;  1DK8 A;  4PNK A;  1EMU A;  4EKD B;  4MK0 A;  4TNB A;  3PVW A;  2EBZ A;  3PSC A;  5HE1 A;  2BV1 A;  5HE0 A;  2D9J A;  3KRW A;  3PVU A;  2JNU A;  2OJ4 A;  2V4Z B;  2IK8 B;  5HE3 A;  1FQJ B;  2ODE B;  3CIK A;  1EZT A;  1FQI A;  5DO9 B; 
#chains in the Genus database with same CATH topology
 2JM5 A;  2CRP A;  1EZY A;  3C7L A;  3KRX A;  2AF0 A;  1OMW A;  5HE2 A;  3C7K B;  4TND A;  3UZT A;  2BCJ A;  2BT2 A;  2IHB B;  2GTP C;  1AGR E;  1CMZ A;  1FQK B;  2DLV A;  2IHD A;  3I5Q A;  3V5W A;  3NYN A;  2OWI A;  3NYO A;  1DK8 A;  4PNK A;  1EMU A;  4EKD B;  4MK0 A;  4HTE A;  4TNB A;  5REQ B;  3PVW A;  2EBZ A;  3PSC A;  5HE1 A;  2BV1 A;  5HE0 A;  2D9J A;  3KRW A;  3PVU A;  2JNU A;  2OJ4 A;  2V4Z B;  2IK8 B;  5HE3 A;  1FQJ B;  2ODE B;  3CIK A;  1EZT A;  3QYF A;  1FQI A;  5DO9 B; 
#chains in the Genus database with same CATH homology
 2JM5 A;  2CRP A;  1EZY A;  3C7L A;  3KRX A;  2AF0 A;  1OMW A;  5HE2 A;  3C7K B;  4TND A;  3UZT A;  2BCJ A;  2BT2 A;  2IHB B;  2GTP C;  1AGR E;  1CMZ A;  1FQK B;  2DLV A;  2IHD A;  3V5W A;  3NYN A;  2OWI A;  3NYO A;  1DK8 A;  4PNK A;  1EMU A;  4EKD B;  4MK0 A;  4TNB A;  5REQ B;  3PVW A;  2EBZ A;  3PSC A;  5HE1 A;  2BV1 A;  5HE0 A;  2D9J A;  3KRW A;  3PVU A;  2JNU A;  2OJ4 A;  2V4Z B;  2IK8 B;  5HE3 A;  1FQJ B;  2ODE B;  3CIK A;  1EZT A;  3QYF A;  1FQI A;  5DO9 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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