The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
105
|
sequence length |
419
|
structure length |
386
|
Chain Sequence |
b'LNIGKKLYEGKTKEVYELLDSPGKVLLQSKGKAAISNKITSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGPEGLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQDVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISLKQADKKIRECNL'
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
publication title |
Octameric structure of the human bifunctional enzyme PAICS in purine biosynthesis.
pubmed doi rcsb |
molecule keywords |
Multifunctional protein ADE2
|
source organism |
Homo sapiens
|
molecule tags |
Ligase, lyase
|
total genus |
105
|
structure length |
386
|
sequence length |
419
|
ec nomenclature |
ec
4.1.1.21: Phosphoribosylaminoimidazole carboxylase. |
pdb deposition date | 2006-05-21 |
chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
---|---|---|---|
A | PF00731 | AIRC | AIR carboxylase |
A | PF01259 | SAICAR_synt | SAICAR synthetase |
cath code
| Class | Architecture | Topology | Homology | Domain |
---|---|---|---|---|---|
Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | PurE domain |