2HC1A

Engineered catalytic domain of protein tyrosine phosphatase hptpbeta.
Total Genus 104
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
290
structure length
288
Chain Sequence
NRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSGGSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDVDIYGAVHDLRLHRVHMVQTEQYVYLHQCVRDVLRARKLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Receptor-type tyrosine-protein phosphatase beta
total genus 104
structure length 288
sequence length 290
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-06-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2hc1A00
4GE5A 1D5RA 4OHIA 1FQ1A 1R6HA 4NYHA 1YFOA 2CJZA 2Y2FA 4RH5A 4QAPA 4JMJA 1ONZA 2A8BA 1WCHA 5KAAA 3NMEA 2BIJA 1U26A 4OHDA 1C84A 5KA1A 1XXVA 1MKPA 3CM3A 2CMCA 2CNHA 2BGEA 1L8KA 5KA9A 3A5KA 3V0HA 2QEPA 1EEOA 5KA4A 2QDPA 1LARA 1NWEA 2P6XA 5EHRA 2VEYA 2B49A 1G4US 3D1QA 1C85A 2I4HA 4OHEA 5K9VA 4WTYA 1ZCLA 5K24A 1T49A 3D44A 3I7ZA 3F99A 2I6IA 2PA5A 1Q6JA 2CM8A 5J8RA 1YTSA 2F70A 1ECVA 5K22A 3F9AA 1I9TA 1V3AA 3V0IA 2QCTA 3I36A 2OOQA 1G1FA 3S4OA 2Q05A 3ZV2A 4KYQA 2FJMA 2FH7A 2DXPA 1VHRA 2F71A 1OEUA 2NTAA 3O5XA 2J16A 3BLTA 2RF6A 5IBSA 2I75A 4ZN5A 1JF7A 1OHDA 4OHLA 1Q6TA 2QBRA 1U25A 2CMBA 3EZZA 1C87A 1PH0A 2P4DA 4Y2EA 1OEOX 4YR8B 4WU3A 1XXPA 3RO1A 2VEXA 3BRHA 1PA9A 3AWFA 4GFUA 2HNQA 3F81A 4JBCA 4ZRTA 2NT2A 4QUNA 4GRYA 2B3OA 3CWEA 1PTYA 1A5YA 1C88A 2CNFA 5GTJA 2I4EA 2NV5A 2PSZA 3QCLA 3MOZA 1YGRA 1Q6MA 4GRZA 1BZHA 2F6ZA 2CM3A 4IKCA 1L8GA 2CFVA 3H2XA 3D42A 3MMJA 4H34A 4S0GA 4B04A 4GE6A 3OMHA 5BX1A 1Q6PA 4NWGA 2C7SA 4HJPA 3QCCA 1BZJA 4GWFA 3QKQA 2J17A 1WAXA 4HRFA 1NL9A 1T48A 1ONYA 2B4UA 1PA1A 1XRIA 2WGPA 4R0SA 2F6FA 2I5XA 2F6YA 2QBQA 4HJQA 1GWZA 4WOHA 2M3VA 3O4SA 4RKKA 4TVVA 1ZCKA 1YTNA 2R0BA 1QXKA 5KABA 1WRMA 3BLUA 3ZM1A 2HCMA 3AWGA 1G7FA 2CNEA 4Z6BA 1LYVA 2NZ6A 1OETA 1OHCA 2CNIA 1YZ4A 1RPMA 5K9WA 1QZ0A 2AZRA 5IBMA 5MMZB 4GFVA 2BGDA 1EENA 3RGQA 2J16B 3QCBA 4WU2A 1I9SA 3ZM0A 3B7OA 3QCIA 3SR9A 4RDDA 5KA8A 4DGXA 4KI9A 3QCFA 2I6MA 5KA7A 3QCMA 1P15A 5KA3A 2IMGA 2QDCA 1Q6SA 3QCKA 3S3HA 4JMKA 2SHPA 2HC2A 1PTVA 2B4OA 3AWEA 1GFYA 1KAVA 2GJTA 1G1HA 3N0AA 4OHHA 4NX8A 4ZI4A 3A5JA 1BZCA 2I6JA 5BZZA 3M4UA 2I3UA 1G7GA 2HXPA 5K25A 4YAAA 1PTTA 2ZN7A 1NZ7A 2I4GA 4DGPA 4GS0A 2ESBA 3EU0A 3QCNA 4RHGA 3S3EA 1C83A 1FPRA 2F6TA 2CNGA 4I8NA 1NNYA 2CMAA 1NWLA 2I3RA 3SMEA 2B4PA 1J4XA 3RGOA 3GXGA 3V0GA 1X24A 4RH9A 4MBBA 4R0TA 5AWXA 2JJDA 2PI7A 4D3RA 5KA2A 1KAKA 1I57A 2HVLA 3EB1A 3EAXA 2F6WA 1ZC0A 4QUMA 3S3FA 3D9CA 1YPTA 2F46A 2CM7A 4J51A 5M43A 3O4UA 2CM2A 2VEVA 4H1OA 3F9BA 3O4TA 1YWFA 1RXDA 1FPZA 2F6VA 4D3PA 1OHEA 3D1HA 2PQ5A 3ZM3A 2OUDA 2GP0A 2VEWA 2H4VA 1U24A 1G1GA 2BZLA 5KADA 1SUGA 1YN9A 4PYHA 2H04A 3QCGA 2NT7A 4BJOA 2AHSA 2Q47A 1XM2A 3QCDA 2ZMMA 1NO6A 3ZMPA 3F41A 3U96A 1ZZWA 5I6VA 5HDEA 2OC3A 3LJ8A 1T4JA 3O3LA 1G4WR 2B4SA 4R30A 1YTWA 4D3QA 4QBWA 1XBOA 3D1OA 2QBSA 2HNPA 2VEUA 4QAHA 4QBEA 2HC1A 2FJNA 2H4GA 3S4EA 5K23A 2Y96A 2MBCA 3ZM2A 3QCHA 3QCJA 2H03A 2B07A 4PVGA 1PXHA 2QBPA 2E0TA 2I6OA 1Q1MA 2GWOA 4Y14A 3EMUA 1AAXA 2I6PA 4NWFA 1OESA 2H4KA 2G6ZA 2H02A 1C86A 2HY3A 5KA0A 3BM8A 1PTUA 1M3GA 3RZ2A 5KACA 2A3KA 2PT0A 5LXQB 1Q6NA 3OLRA 1OEMX 4ICZA 1YGUA 4RI4A 3MOWA 2NLKA 3S3KA 3V0JA 2I42A 3V0DA 2PBNA 4NNDA 2QCJA 2QDMA 4RI5A 4ERCA 2YDUA 1JLNA 3V0EA 2OZ5A 4KYRA 3QKPA 3PS5A 3ZMQA 2G59A 3QCEA 2C46A 2BV5A 3GXHA 3V0FA 1PYNA 5EHPA 3I80A 5BUGA 4AZ1A 4GE2A 2I1YA 4JNBA 2HB1A 1LQFA 4BPCA 5BZXA 1OEVA
chains in the Genus database with same CATH superfamily
4GE5A 1D5RA 4OHIA 1FQ1A 2VTDA 4QF5A 1R6HA 1E0DA 2Y67A 3ZM6A 4NYHA 1YFOA 2CJZA 2Y2FA 4RH5A 4QAPA 4JMJA 1ONZA 2A8BA 1WCHA 5KAAA 5A5EA 3NMEA 2BIJA 2F00A 1U26A 4OHDA 1C84A 5KA1A 1XXVA 1MKPA 3CM3A 2CMCA 2CNHA 2BGEA 1L8KA 2VOSA 5KA9A 3A5KA 3V0HA 2QEPA 1EEOA 5KA4A 2QDPA 1LARA 1NWEA 2P6XA 5EHRA 2VEYA 2B49A 1G4US 3D1QA 1C85A 4C12A 2I4HA 4OHEA 5K9VA 4WTYA 1ZCLA 2JFGA 5K24A 1T49A 3D44A 3I7ZA 3F99A 2I6IA 2PA5A 1Q6JA 2CM8A 5J8RA 1YTSA 2F70A 1ECVA 5K22A 1JBVA 3F9AA 1I9TA 1V3AA 3V0IA 2QCTA 3I36A 2OOQA 1G1FA 3S4OA 2Q05A 3ZV2A 4KYQA 2FJMA 2FH7A 2DXPA 1VHRA 1J6UA 2F71A 1OEUA 2NTAA 3O5XA 2J16A 3BLTA 2RF6A 2Y1OA 5IBSA 2I75A 4ZN5A 1JF7A 1OHDA 4OHLA 1Q6TA 2QBRA 1U25A 2CMBA 3EZZA 1C87A 1PH0A 2P4DA 4Y2EA 1OEOX 4YR8B 4WU3A 1XXPA 3RO1A 2VEXA 3BRHA 2UUPA 1PA9A 3AWFA 4GFUA 2HNQA 3F81A 4JBCA 4ZRTA 2NT2A 4QUNA 4GRYA 2B3OA 3CWEA 1PTYA 1W78A 1A5YA 1C88A 2CNFA 5GTJA 2I4EA 2NV5A 2PSZA 3QCLA 3MOZA 1YGRA 2JFFA 3NRSA 1Q6MA 4GRZA 1BZHA 2F6ZA 2CM3A 1P3DA 4IKCA 1L8GA 2CFVA 3H2XA 3D42A 3MMJA 4H34A 4S0GA 4B04A 4GE6A 3OMHA 5BX1A 1Q6PA 4NWGA 2C7SA 4HJPA 3QCCA 1BZJA 4GWFA 3MVNA 3QKQA 2J17A 1WAXA 4HRFA 1NL9A 1T48A 1ONYA 2B4UA 1PA1A 1XRIA 2WGPA 4R0SA 2F6FA 2I5XA 1JBWA 2F6YA 2QBQA 4HJQA 1GWZA 4WOHA 2M3VA 3O4SA 4RKKA 4TVVA 1ZCKA 1YTNA 2R0BA 1QXKA 5KABA 1WRMA 3BLUA 3ZM1A 2HCMA 1GG4A 3AWGA 1G7FA 2CNEA 4Z6BA 1LYVA 2NZ6A 1OETA 1OHCA 2CNIA 2VORA 1YZ4A 1RPMA 5K9WA 1QZ0A 2AZRA 5IBMA 5MMZB 4GFVA 2BGDA 1EENA 3RGQA 2J16B 3QCBA 4WU2A 1I9SA 3ZM0A 3B7OA 2Y66A 3QCIA 3SR9A 4RDDA 5KA8A 4DGXA 1EEHA 4KI9A 4ZIYA 3QCFA 2I6MA 5KA7A 3QCMA 1P15A 5KA3A 2IMGA 2QDCA 1Q6SA 3QCKA 3S3HA 4JMKA 2SHPA 2HC2A 2WTZA 1PTVA 2B4OA 3AWEA 1GFYA 1KAVA 2GJTA 2AM2A 1UAGA 1G1HA 2XJAA 3N0AA 4OHHA 4NX8A 4ZI4A 3A5JA 1BZCA 2I6JA 5BZZA 3M4UA 2I3UA 2GCBA 4HV4A 1G7GA 5A5FA 2HXPA 5K25A 4YAAA 1PTTA 2ZN7A 1NZ7A 2I4GA 4DGPA 4GS0A 2ESBA 2XPCA 3EU0A 3QCNA 4RHGA 4BUBA 2VTEA 1W7KA 3S3EA 1C83A 1FPRA 2F6TA 2CNGA 4I8NA 1NNYA 2CMAA 1NWLA 2I3RA 3SMEA 2B4PA 1J4XA 3RGOA 3GXGA 3V0GA 1X24A 2AM1A 4RH9A 4MBBA 3PYZA 4R0TA 5AWXA 2JJDA 2PI7A 4D3RA 5KA2A 1KAKA 1I57A 2HVLA 3EB1A 3EAXA 2F6WA 1ZC0A 4QUMA 3S3FA 3D9CA 1YPTA 2F46A 2WJPA 2CM7A 1GQQA 4QDIA 4J51A 1FGSA 5M43A 3O4UA 2CM2A 2VEVA 4H1OA 3F9BA 3O4TA 1YWFA 1RXDA 1FPZA 2F6VA 4D3PA 1OHEA 3N2AA 3D1HA 2PQ5A 3ZM3A 2GC6A 2OUDA 2GP0A 2VEWA 4CVMA 2H4VA 1U24A 3ZL8A 1G1GA 2BZLA 5KADA 1SUGA 1YN9A 4PYHA 3UAGA 4C13A 2H04A 3QCGA 2NT7A 4BJOA 2AHSA 2Q47A 1XM2A 3QCDA 2ZMMA 1NO6A 3ZMPA 3F41A 3U96A 1ZZWA 2X5OA 3HN7A 5I6VA 5HDEA 2OC3A 3LJ8A 1T4JA 3O3LA 1G4WR 2B4SA 4R30A 3ZM5A 1GQYA 1YTWA 4D3QA 4QBWA 1XBOA 3D1OA 2QBSA 2HNPA 2VEUA 4QAHA 4QBEA 2HC1A 2FJNA 2H4GA 3S4EA 5K23A 4UAGA 2Y96A 2MBCA 3ZM2A 3QCHA 3QCJA 2H03A 2B07A 4PVGA 1PXHA 2QBPA 4BUCA 2E0TA 2I6OA 1Q1MA 2GWOA 4Y14A 3EMUA 2UAGA 1AAXA 2I6PA 4NWFA 1OESA 2H4KA 2G6ZA 2H02A 1C86A 2HY3A 5KA0A 3BM8A 1PTUA 2GC5A 1M3GA 3RZ2A 5KACA 1E8CA 2GCAA 2A3KA 2PT0A 4CVKA 5LXQB 1Q6NA 1P31A 3OLRA 1OEMX 4ICZA 1YGUA 4RI4A 3MOWA 2NLKA 2UUOA 3S3KA 3V0JA 2I42A 3V0DA 2PBNA 3QCZA 4NNDA 2QCJA 2QDMA 4CVLA 4RI5A 4ERCA 2YDUA 3LK7A 1JLNA 3V0EA 2OZ5A 4KYRA 3QKPA 3PS5A 1O5ZA 3ZMQA 2G59A 3QCEA 2C46A 2BV5A 2Y68A 3GXHA 3V0FA 1PYNA 5EHPA 3I80A 5BUGA 4AZ1A 4GE2A 2I1YA 2JFHA 4JNBA 2HB1A 1LQFA 4BPCA 5BZXA 1OEVA
chains in the Genus database with same CATH topology
4GE5A 1D5RA 4OHIA 1FQ1A 1R6HA 4NYHA 1YFOA 2CJZA 2Y2FA 4RH5A 4QAPA 4JMJA 1ONZA 2A8BA 1WCHA 5KAAA 3NMEA 2BIJA 1U26A 4OHDA 1C84A 5KA1A 1XXVA 1MKPA 3CM3A 2CMCA 2CNHA 2BGEA 1L8KA 5KA9A 3A5KA 3V0HA 2QEPA 1EEOA 5KA4A 2QDPA 1LARA 1NWEA 2P6XA 5EHRA 2VEYA 2B49A 1G4US 3D1QA 1C85A 2I4HA 4OHEA 5K9VA 4WTYA 1ZCLA 5K24A 1T49A 3D44A 3I7ZA 3F99A 2I6IA 2PA5A 1Q6JA 2CM8A 5J8RA 1YTSA 2F70A 1ECVA 5K22A 3F9AA 1I9TA 1V3AA 3V0IA 2QCTA 3I36A 2OOQA 1G1FA 3S4OA 2Q05A 3ZV2A 4KYQA 2FJMA 2FH7A 2DXPA 1VHRA 2F71A 1OEUA 2NTAA 3O5XA 2J16A 3BLTA 2RF6A 5IBSA 2I75A 4ZN5A 1JF7A 1OHDA 4OHLA 1Q6TA 2QBRA 1U25A 2CMBA 3EZZA 1C87A 1PH0A 2P4DA 4Y2EA 1OEOX 4YR8B 4WU3A 1XXPA 3RO1A 2VEXA 3BRHA 1PA9A 3AWFA 4GFUA 2HNQA 3F81A 4JBCA 4ZRTA 2NT2A 4QUNA 4GRYA 2B3OA 3CWEA 1PTYA 1A5YA 1C88A 2CNFA 5GTJA 2I4EA 2NV5A 2PSZA 3QCLA 3MOZA 1YGRA 1Q6MA 4GRZA 1BZHA 2F6ZA 2CM3A 4IKCA 1L8GA 2CFVA 3H2XA 3D42A 3MMJA 4H34A 4S0GA 4B04A 4GE6A 3OMHA 5BX1A 1Q6PA 4NWGA 2C7SA 4HJPA 3QCCA 1BZJA 4GWFA 3QKQA 2J17A 1WAXA 4HRFA 1NL9A 1T48A 1ONYA 2B4UA 1PA1A 1XRIA 2WGPA 4R0SA 2F6FA 2I5XA 2F6YA 2QBQA 4HJQA 1GWZA 4WOHA 2M3VA 3O4SA 4RKKA 4TVVA 1ZCKA 1YTNA 2R0BA 1QXKA 5KABA 1WRMA 3BLUA 3ZM1A 2HCMA 3AWGA 1G7FA 2CNEA 4Z6BA 1LYVA 2NZ6A 1OETA 1OHCA 2CNIA 1YZ4A 1RPMA 5K9WA 1QZ0A 2AZRA 5IBMA 5MMZB 4GFVA 2BGDA 1EENA 3RGQA 2J16B 3QCBA 4WU2A 1I9SA 3ZM0A 3B7OA 3QCIA 3SR9A 4RDDA 5KA8A 4DGXA 4KI9A 3QCFA 2I6MA 5KA7A 3QCMA 1P15A 5KA3A 2IMGA 2QDCA 1Q6SA 3QCKA 3S3HA 4JMKA 2SHPA 2HC2A 1PTVA 2B4OA 3AWEA 1GFYA 1KAVA 2GJTA 1G1HA 3N0AA 4OHHA 4NX8A 4ZI4A 3A5JA 1BZCA 2I6JA 5BZZA 3M4UA 2I3UA 1G7GA 2HXPA 5K25A 4YAAA 1PTTA 2ZN7A 1NZ7A 2I4GA 4DGPA 4GS0A 2ESBA 3EU0A 3QCNA 4RHGA 3S3EA 1C83A 1FPRA 2F6TA 2CNGA 4I8NA 1NNYA 2CMAA 1NWLA 2I3RA 3SMEA 2B4PA 1J4XA 3RGOA 3GXGA 3V0GA 1X24A 4RH9A 4MBBA 4R0TA 5AWXA 2JJDA 2PI7A 4D3RA 5KA2A 1KAKA 1I57A 2HVLA 3EB1A 3EAXA 2F6WA 1ZC0A 4QUMA 3S3FA 3D9CA 1YPTA 2F46A 2CM7A 4J51A 5M43A 3O4UA 2CM2A 2VEVA 4H1OA 3F9BA 3O4TA 1YWFA 1RXDA 1FPZA 2F6VA 4D3PA 1OHEA 3D1HA 2PQ5A 3ZM3A 2OUDA 2GP0A 2VEWA 2H4VA 1U24A 1G1GA 2BZLA 5KADA 1SUGA 1YN9A 4PYHA 2H04A 3QCGA 2NT7A 4BJOA 2AHSA 2Q47A 1XM2A 3QCDA 2ZMMA 1NO6A 3ZMPA 3F41A 3U96A 1ZZWA 5I6VA 5HDEA 2OC3A 3LJ8A 1T4JA 3O3LA 1G4WR 2B4SA 4R30A 1YTWA 4D3QA 4QBWA 1XBOA 3D1OA 2QBSA 2HNPA 2VEUA 4QAHA 4QBEA 2HC1A 2FJNA 2H4GA 3S4EA 5K23A 2Y96A 2MBCA 3ZM2A 3QCHA 3QCJA 2H03A 2B07A 4PVGA 1PXHA 2QBPA 2E0TA 2I6OA 1Q1MA 2GWOA 4Y14A 3EMUA 1AAXA 2I6PA 4NWFA 1OESA 2H4KA 2G6ZA 2H02A 1C86A 2HY3A 5KA0A 3BM8A 1PTUA 1M3GA 3RZ2A 5KACA 2A3KA 2PT0A 5LXQB 1Q6NA 3OLRA 1OEMX 4ICZA 1YGUA 4RI4A 3MOWA 2NLKA 3S3KA 3V0JA 2I42A 3V0DA 2PBNA 4NNDA 2QCJA 2QDMA 4RI5A 4ERCA 2YDUA 1JLNA 3V0EA 2OZ5A 4KYRA 3QKPA 3PS5A 3ZMQA 2G59A 3QCEA 2C46A 2BV5A 3GXHA 3V0FA 1PYNA 5EHPA 3I80A 5BUGA 4AZ1A 4GE2A 2I1YA 4JNBA 2HB1A 1LQFA 4BPCA 5BZXA 1OEVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GE5 A;  1D5R A;  4OHI A;  1FQ1 A;  1R6H A;  4NYH A;  1YFO A;  2CJZ A;  2Y2F A;  4RH5 A;  4QAP A;  4JMJ A;  1ONZ A;  2A8B A;  1WCH A;  5KAA A;  3NME A;  2BIJ A;  1U26 A;  4OHD A;  1C84 A;  5KA1 A;  1XXV A;  1MKP A;  3CM3 A;  2CMC A;  2CNH A;  2BGE A;  1L8K A;  5KA9 A;  3A5K A;  3V0H A;  2QEP A;  1EEO A;  5KA4 A;  2QDP A;  1LAR A;  1NWE A;  2P6X A;  5EHR A;  2VEY A;  2B49 A;  1G4U S;  3D1Q A;  1C85 A;  2I4H A;  4OHE A;  5K9V A;  4WTY A;  1ZCL A;  5K24 A;  1T49 A;  3D44 A;  3I7Z A;  3F99 A;  2I6I A;  2PA5 A;  1Q6J A;  2CM8 A;  5J8R A;  1YTS A;  2F70 A;  1ECV A;  5K22 A;  3F9A A;  1I9T A;  1V3A A;  3V0I A;  2QCT A;  3I36 A;  2OOQ A;  1G1F A;  3S4O A;  2Q05 A;  3ZV2 A;  4KYQ A;  2FJM A;  2FH7 A;  2DXP A;  1VHR A;  2F71 A;  1OEU A;  2NTA A;  3O5X A;  2J16 A;  3BLT A;  2RF6 A;  5IBS A;  2I75 A;  4ZN5 A;  1JF7 A;  1OHD A;  4OHL A;  1Q6T A;  2QBR A;  1U25 A;  2CMB A;  3EZZ A;  1C87 A;  1PH0 A;  2P4D A;  4Y2E A;  1OEO X;  4YR8 B;  4WU3 A;  1XXP A;  3RO1 A;  2VEX A;  3BRH A;  1PA9 A;  3AWF A;  4GFU A;  2HNQ A;  3F81 A;  4JBC A;  4ZRT A;  2NT2 A;  4QUN A;  4GRY A;  2B3O A;  3CWE A;  1PTY A;  1A5Y A;  1C88 A;  2CNF A;  5GTJ A;  2I4E A;  2NV5 A;  2PSZ A;  3QCL A;  3MOZ A;  1YGR A;  1Q6M A;  4GRZ A;  1BZH A;  2F6Z A;  2CM3 A;  4IKC A;  1L8G A;  2CFV A;  3H2X A;  3D42 A;  3MMJ A;  4H34 A;  4S0G A;  4B04 A;  4GE6 A;  3OMH A;  5BX1 A;  1Q6P A;  4NWG A;  2C7S A;  4HJP A;  3QCC A;  1BZJ A;  4GWF A;  3QKQ A;  2J17 A;  1WAX A;  4HRF A;  1NL9 A;  1T48 A;  1ONY A;  2B4U A;  1PA1 A;  1XRI A;  2WGP A;  4R0S A;  2F6F A;  2I5X A;  2F6Y A;  2QBQ A;  4HJQ A;  1GWZ A;  4WOH A;  2M3V A;  3O4S A;  4RKK A;  4TVV A;  1ZCK A;  1YTN A;  2R0B A;  1QXK A;  5KAB A;  1WRM A;  3BLU A;  3ZM1 A;  2HCM A;  3AWG A;  1G7F A;  2CNE A;  4Z6B A;  1LYV A;  2NZ6 A;  1OET A;  1OHC A;  2CNI A;  1YZ4 A;  1RPM A;  5K9W A;  1QZ0 A;  2AZR A;  5IBM A;  5MMZ B;  4GFV A;  2BGD A;  1EEN A;  3RGQ A;  2J16 B;  3QCB A;  4WU2 A;  1I9S A;  3ZM0 A;  3B7O A;  3QCI A;  3SR9 A;  4RDD A;  5KA8 A;  4DGX A;  4KI9 A;  3QCF A;  2I6M A;  5KA7 A;  3QCM A;  1P15 A;  5KA3 A;  2IMG A;  2QDC A;  1Q6S A;  3QCK A;  3S3H A;  4JMK A;  2SHP A;  2HC2 A;  1PTV A;  2B4O A;  3AWE A;  1GFY A;  1KAV A;  2GJT A;  1G1H A;  3N0A A;  4OHH A;  4NX8 A;  4ZI4 A;  3A5J A;  1BZC A;  2I6J A;  5BZZ A;  3M4U A;  2I3U A;  1G7G A;  2HXP A;  5K25 A;  4YAA A;  1PTT A;  2ZN7 A;  1NZ7 A;  2I4G A;  4DGP A;  4GS0 A;  2ESB A;  3EU0 A;  3QCN A;  4RHG A;  3S3E A;  1C83 A;  1FPR A;  2F6T A;  2CNG A;  4I8N A;  1NNY A;  2CMA A;  1NWL A;  2I3R A;  3SME A;  2B4P A;  1J4X A;  3RGO A;  3GXG A;  3V0G A;  1X24 A;  4RH9 A;  4MBB A;  4R0T A;  5AWX A;  2JJD A;  2PI7 A;  4D3R A;  5KA2 A;  1KAK A;  1I57 A;  2HVL A;  3EB1 A;  3EAX A;  2F6W A;  1ZC0 A;  4QUM A;  3S3F A;  3D9C A;  1YPT A;  2F46 A;  2CM7 A;  4J51 A;  5M43 A;  3O4U A;  2CM2 A;  2VEV A;  4H1O A;  3F9B A;  3O4T A;  1YWF A;  1RXD A;  1FPZ A;  2F6V A;  4D3P A;  1OHE A;  3D1H A;  2PQ5 A;  3ZM3 A;  2OUD A;  2GP0 A;  2VEW A;  2H4V A;  1U24 A;  1G1G A;  2BZL A;  5KAD A;  1SUG A;  1YN9 A;  4PYH A;  2H04 A;  3QCG A;  2NT7 A;  4BJO A;  2AHS A;  2Q47 A;  1XM2 A;  3QCD A;  2ZMM A;  1NO6 A;  3ZMP A;  3F41 A;  3U96 A;  1ZZW A;  5I6V A;  5HDE A;  2OC3 A;  3LJ8 A;  1T4J A;  3O3L A;  1G4W R;  2B4S A;  4R30 A;  1YTW A;  4D3Q A;  4QBW A;  1XBO A;  3D1O A;  2QBS A;  2HNP A;  2VEU A;  4QAH A;  4QBE A;  2HC1 A;  2FJN A;  2H4G A;  3S4E A;  5K23 A;  2Y96 A;  2MBC A;  3ZM2 A;  3QCH A;  3QCJ A;  2H03 A;  2B07 A;  4PVG A;  1PXH A;  2QBP A;  2E0T A;  2I6O A;  1Q1M A;  2GWO A;  4Y14 A;  3EMU A;  1AAX A;  2I6P A;  4NWF A;  1OES A;  2H4K A;  2G6Z A;  2H02 A;  1C86 A;  2HY3 A;  5KA0 A;  3BM8 A;  1PTU A;  1M3G A;  3RZ2 A;  5KAC A;  2A3K A;  2PT0 A;  5LXQ B;  1Q6N A;  3OLR A;  1OEM X;  4ICZ A;  1YGU A;  4RI4 A;  3MOW A;  2NLK A;  3S3K A;  3V0J A;  2I42 A;  3V0D A;  2PBN A;  4NND A;  2QCJ A;  2QDM A;  4RI5 A;  4ERC A;  2YDU A;  1JLN A;  3V0E A;  2OZ5 A;  4KYR A;  3QKP A;  3PS5 A;  3ZMQ A;  2G59 A;  3QCE A;  2C46 A;  2BV5 A;  3GXH A;  3V0F A;  1PYN A;  5EHP A;  3I80 A;  5BUG A;  4AZ1 A;  4GE2 A;  2I1Y A;  4JNB A;  2HB1 A;  1LQF A;  4BPC A;  5BZX A;  1OEV A; 
#chains in the Genus database with same CATH topology
 4GE5 A;  1D5R A;  4OHI A;  1FQ1 A;  2VTD A;  4QF5 A;  1R6H A;  1E0D A;  2Y67 A;  3ZM6 A;  4NYH A;  1YFO A;  2CJZ A;  2Y2F A;  4RH5 A;  4QAP A;  4JMJ A;  1ONZ A;  2A8B A;  1WCH A;  5KAA A;  5A5E A;  3NME A;  2BIJ A;  2F00 A;  1U26 A;  4OHD A;  1C84 A;  5KA1 A;  1XXV A;  1MKP A;  3CM3 A;  2CMC A;  2CNH A;  2BGE A;  1L8K A;  2VOS A;  5KA9 A;  3A5K A;  3V0H A;  2QEP A;  1EEO A;  5KA4 A;  2QDP A;  1LAR A;  1NWE A;  2P6X A;  5EHR A;  2VEY A;  2B49 A;  1G4U S;  3D1Q A;  1C85 A;  4C12 A;  2I4H A;  4OHE A;  5K9V A;  4WTY A;  1ZCL A;  2JFG A;  5K24 A;  1T49 A;  3D44 A;  3I7Z A;  3F99 A;  2I6I A;  2PA5 A;  1Q6J A;  2CM8 A;  5J8R A;  1YTS A;  2F70 A;  1ECV A;  5K22 A;  1JBV A;  3F9A A;  1I9T A;  1V3A A;  3V0I A;  2QCT A;  3I36 A;  2OOQ A;  1G1F A;  3S4O A;  2Q05 A;  3ZV2 A;  4KYQ A;  2FJM A;  2FH7 A;  2DXP A;  1VHR A;  1J6U A;  2F71 A;  1OEU A;  2NTA A;  3O5X A;  2J16 A;  3BLT A;  2RF6 A;  2Y1O A;  5IBS A;  2I75 A;  4ZN5 A;  1JF7 A;  1OHD A;  4OHL A;  1Q6T A;  2QBR A;  1U25 A;  2CMB A;  3EZZ A;  1C87 A;  1PH0 A;  2P4D A;  4Y2E A;  1OEO X;  4YR8 B;  4WU3 A;  1XXP A;  3RO1 A;  2VEX A;  3BRH A;  2UUP A;  1PA9 A;  3AWF A;  4GFU A;  2HNQ A;  3F81 A;  4JBC A;  4ZRT A;  2NT2 A;  4QUN A;  4GRY A;  2B3O A;  3CWE A;  1PTY A;  1W78 A;  1A5Y A;  1C88 A;  2CNF A;  5GTJ A;  2I4E A;  2NV5 A;  2PSZ A;  3QCL A;  3MOZ A;  1YGR A;  2JFF A;  3NRS A;  1Q6M A;  4GRZ A;  1BZH A;  2F6Z A;  2CM3 A;  1P3D A;  4IKC A;  1L8G A;  2CFV A;  3H2X A;  3D42 A;  3MMJ A;  4H34 A;  4S0G A;  4B04 A;  4GE6 A;  3OMH A;  5BX1 A;  1Q6P A;  4NWG A;  2C7S A;  4HJP A;  3QCC A;  1BZJ A;  4GWF A;  3MVN A;  3QKQ A;  2J17 A;  1WAX A;  4HRF A;  1NL9 A;  1T48 A;  1ONY A;  2B4U A;  1PA1 A;  1XRI A;  2WGP A;  4R0S A;  2F6F A;  2I5X A;  1JBW A;  2F6Y A;  2QBQ A;  4HJQ A;  1GWZ A;  4WOH A;  2M3V A;  3O4S A;  4RKK A;  4TVV A;  1ZCK A;  1YTN A;  2R0B A;  1QXK A;  5KAB A;  1WRM A;  3BLU A;  3ZM1 A;  2HCM A;  1GG4 A;  3AWG A;  1G7F A;  2CNE A;  4Z6B A;  1LYV A;  2NZ6 A;  1OET A;  1OHC A;  2CNI A;  2VOR A;  1YZ4 A;  1RPM A;  5K9W A;  1QZ0 A;  2AZR A;  5IBM A;  5MMZ B;  4GFV A;  2BGD A;  1EEN A;  3RGQ A;  2J16 B;  3QCB A;  4WU2 A;  1I9S A;  3ZM0 A;  3B7O A;  2Y66 A;  3QCI A;  3SR9 A;  4RDD A;  5KA8 A;  4DGX A;  1EEH A;  4KI9 A;  4ZIY A;  3QCF A;  2I6M A;  5KA7 A;  3QCM A;  1P15 A;  5KA3 A;  2IMG A;  2QDC A;  1Q6S A;  3QCK A;  3S3H A;  4JMK A;  2SHP A;  2HC2 A;  2WTZ A;  1PTV A;  2B4O A;  3AWE A;  1GFY A;  1KAV A;  2GJT A;  2AM2 A;  1UAG A;  1G1H A;  2XJA A;  3N0A A;  4OHH A;  4NX8 A;  4ZI4 A;  3A5J A;  1BZC A;  2I6J A;  5BZZ A;  3M4U A;  2I3U A;  2GCB A;  4HV4 A;  1G7G A;  5A5F A;  2HXP A;  5K25 A;  4YAA A;  1PTT A;  2ZN7 A;  1NZ7 A;  2I4G A;  4DGP A;  4GS0 A;  2ESB A;  2XPC A;  3EU0 A;  3QCN A;  4RHG A;  4BUB A;  2VTE A;  1W7K A;  3S3E A;  1C83 A;  1FPR A;  2F6T A;  2CNG A;  4I8N A;  1NNY A;  2CMA A;  1NWL A;  2I3R A;  3SME A;  2B4P A;  1J4X A;  3RGO A;  3GXG A;  3V0G A;  1X24 A;  2AM1 A;  4RH9 A;  4MBB A;  3PYZ A;  4R0T A;  5AWX A;  2JJD A;  2PI7 A;  4D3R A;  5KA2 A;  1KAK A;  1I57 A;  2HVL A;  3EB1 A;  3EAX A;  2F6W A;  1ZC0 A;  4QUM A;  3S3F A;  3D9C A;  1YPT A;  2F46 A;  2WJP A;  2CM7 A;  1GQQ A;  4QDI A;  4J51 A;  1FGS A;  5M43 A;  3O4U A;  2CM2 A;  2VEV A;  4H1O A;  3F9B A;  3O4T A;  1YWF A;  1RXD A;  1FPZ A;  2F6V A;  4D3P A;  1OHE A;  3N2A A;  3D1H A;  2PQ5 A;  3ZM3 A;  2GC6 A;  2OUD A;  2GP0 A;  2VEW A;  4CVM A;  2H4V A;  1U24 A;  3ZL8 A;  1G1G A;  2BZL A;  5KAD A;  1SUG A;  1YN9 A;  4PYH A;  3UAG A;  4C13 A;  2H04 A;  3QCG A;  2NT7 A;  4BJO A;  2AHS A;  2Q47 A;  1XM2 A;  3QCD A;  2ZMM A;  1NO6 A;  3ZMP A;  3F41 A;  3U96 A;  1ZZW A;  2X5O A;  3HN7 A;  5I6V A;  5HDE A;  2OC3 A;  3LJ8 A;  1T4J A;  3O3L A;  1G4W R;  2B4S A;  4R30 A;  3ZM5 A;  1GQY A;  1YTW A;  4D3Q A;  4QBW A;  1XBO A;  3D1O A;  2QBS A;  2HNP A;  2VEU A;  4QAH A;  4QBE A;  2HC1 A;  2FJN A;  2H4G A;  3S4E A;  5K23 A;  4UAG A;  2Y96 A;  2MBC A;  3ZM2 A;  3QCH A;  3QCJ A;  2H03 A;  2B07 A;  4PVG A;  1PXH A;  2QBP A;  4BUC A;  2E0T A;  2I6O A;  1Q1M A;  2GWO A;  4Y14 A;  3EMU A;  2UAG A;  1AAX A;  2I6P A;  4NWF A;  1OES A;  2H4K A;  2G6Z A;  2H02 A;  1C86 A;  2HY3 A;  5KA0 A;  3BM8 A;  1PTU A;  2GC5 A;  1M3G A;  3RZ2 A;  5KAC A;  1E8C A;  2GCA A;  2A3K A;  2PT0 A;  4CVK A;  5LXQ B;  1Q6N A;  1P31 A;  3OLR A;  1OEM X;  4ICZ A;  1YGU A;  4RI4 A;  3MOW A;  2NLK A;  2UUO A;  3S3K A;  3V0J A;  2I42 A;  3V0D A;  2PBN A;  3QCZ A;  4NND A;  2QCJ A;  2QDM A;  4CVL A;  4RI5 A;  4ERC A;  2YDU A;  3LK7 A;  1JLN A;  3V0E A;  2OZ5 A;  4KYR A;  3QKP A;  3PS5 A;  1O5Z A;  3ZMQ A;  2G59 A;  3QCE A;  2C46 A;  2BV5 A;  2Y68 A;  3GXH A;  3V0F A;  1PYN A;  5EHP A;  3I80 A;  5BUG A;  4AZ1 A;  4GE2 A;  2I1Y A;  2JFH A;  4JNB A;  2HB1 A;  1LQF A;  4BPC A;  5BZX A;  1OEV A; 
#chains in the Genus database with same CATH homology
 4GE5 A;  1D5R A;  4OHI A;  1FQ1 A;  1R6H A;  4NYH A;  1YFO A;  2CJZ A;  2Y2F A;  4RH5 A;  4QAP A;  4JMJ A;  1ONZ A;  2A8B A;  1WCH A;  5KAA A;  3NME A;  2BIJ A;  1U26 A;  4OHD A;  1C84 A;  5KA1 A;  1XXV A;  1MKP A;  3CM3 A;  2CMC A;  2CNH A;  2BGE A;  1L8K A;  5KA9 A;  3A5K A;  3V0H A;  2QEP A;  1EEO A;  5KA4 A;  2QDP A;  1LAR A;  1NWE A;  2P6X A;  5EHR A;  2VEY A;  2B49 A;  1G4U S;  3D1Q A;  1C85 A;  2I4H A;  4OHE A;  5K9V A;  4WTY A;  1ZCL A;  5K24 A;  1T49 A;  3D44 A;  3I7Z A;  3F99 A;  2I6I A;  2PA5 A;  1Q6J A;  2CM8 A;  5J8R A;  1YTS A;  2F70 A;  1ECV A;  5K22 A;  3F9A A;  1I9T A;  1V3A A;  3V0I A;  2QCT A;  3I36 A;  2OOQ A;  1G1F A;  3S4O A;  2Q05 A;  3ZV2 A;  4KYQ A;  2FJM A;  2FH7 A;  2DXP A;  1VHR A;  2F71 A;  1OEU A;  2NTA A;  3O5X A;  2J16 A;  3BLT A;  2RF6 A;  5IBS A;  2I75 A;  4ZN5 A;  1JF7 A;  1OHD A;  4OHL A;  1Q6T A;  2QBR A;  1U25 A;  2CMB A;  3EZZ A;  1C87 A;  1PH0 A;  2P4D A;  4Y2E A;  1OEO X;  4YR8 B;  4WU3 A;  1XXP A;  3RO1 A;  2VEX A;  3BRH A;  1PA9 A;  3AWF A;  4GFU A;  2HNQ A;  3F81 A;  4JBC A;  4ZRT A;  2NT2 A;  4QUN A;  4GRY A;  2B3O A;  3CWE A;  1PTY A;  1A5Y A;  1C88 A;  2CNF A;  5GTJ A;  2I4E A;  2NV5 A;  2PSZ A;  3QCL A;  3MOZ A;  1YGR A;  1Q6M A;  4GRZ A;  1BZH A;  2F6Z A;  2CM3 A;  4IKC A;  1L8G A;  2CFV A;  3H2X A;  3D42 A;  3MMJ A;  4H34 A;  4S0G A;  4B04 A;  4GE6 A;  3OMH A;  5BX1 A;  1Q6P A;  4NWG A;  2C7S A;  4HJP A;  3QCC A;  1BZJ A;  4GWF A;  3QKQ A;  2J17 A;  1WAX A;  4HRF A;  1NL9 A;  1T48 A;  1ONY A;  2B4U A;  1PA1 A;  1XRI A;  2WGP A;  4R0S A;  2F6F A;  2I5X A;  2F6Y A;  2QBQ A;  4HJQ A;  1GWZ A;  4WOH A;  2M3V A;  3O4S A;  4RKK A;  4TVV A;  1ZCK A;  1YTN A;  2R0B A;  1QXK A;  5KAB A;  1WRM A;  3BLU A;  3ZM1 A;  2HCM A;  3AWG A;  1G7F A;  2CNE A;  4Z6B A;  1LYV A;  2NZ6 A;  1OET A;  1OHC A;  2CNI A;  1YZ4 A;  1RPM A;  5K9W A;  1QZ0 A;  2AZR A;  5IBM A;  5MMZ B;  4GFV A;  2BGD A;  1EEN A;  3RGQ A;  2J16 B;  3QCB A;  4WU2 A;  1I9S A;  3ZM0 A;  3B7O A;  3QCI A;  3SR9 A;  4RDD A;  5KA8 A;  4DGX A;  4KI9 A;  3QCF A;  2I6M A;  5KA7 A;  3QCM A;  1P15 A;  5KA3 A;  2IMG A;  2QDC A;  1Q6S A;  3QCK A;  3S3H A;  4JMK A;  2SHP A;  2HC2 A;  1PTV A;  2B4O A;  3AWE A;  1GFY A;  1KAV A;  2GJT A;  1G1H A;  3N0A A;  4OHH A;  4NX8 A;  4ZI4 A;  3A5J A;  1BZC A;  2I6J A;  5BZZ A;  3M4U A;  2I3U A;  1G7G A;  2HXP A;  5K25 A;  4YAA A;  1PTT A;  2ZN7 A;  1NZ7 A;  2I4G A;  4DGP A;  4GS0 A;  2ESB A;  3EU0 A;  3QCN A;  4RHG A;  3S3E A;  1C83 A;  1FPR A;  2F6T A;  2CNG A;  4I8N A;  1NNY A;  2CMA A;  1NWL A;  2I3R A;  3SME A;  2B4P A;  1J4X A;  3RGO A;  3GXG A;  3V0G A;  1X24 A;  4RH9 A;  4MBB A;  4R0T A;  5AWX A;  2JJD A;  2PI7 A;  4D3R A;  5KA2 A;  1KAK A;  1I57 A;  2HVL A;  3EB1 A;  3EAX A;  2F6W A;  1ZC0 A;  4QUM A;  3S3F A;  3D9C A;  1YPT A;  2F46 A;  2CM7 A;  4J51 A;  5M43 A;  3O4U A;  2CM2 A;  2VEV A;  4H1O A;  3F9B A;  3O4T A;  1YWF A;  1RXD A;  1FPZ A;  2F6V A;  4D3P A;  1OHE A;  3D1H A;  2PQ5 A;  3ZM3 A;  2OUD A;  2GP0 A;  2VEW A;  2H4V A;  1U24 A;  1G1G A;  2BZL A;  5KAD A;  1SUG A;  1YN9 A;  4PYH A;  2H04 A;  3QCG A;  2NT7 A;  4BJO A;  2AHS A;  2Q47 A;  1XM2 A;  3QCD A;  2ZMM A;  1NO6 A;  3ZMP A;  3F41 A;  3U96 A;  1ZZW A;  5I6V A;  5HDE A;  2OC3 A;  3LJ8 A;  1T4J A;  3O3L A;  1G4W R;  2B4S A;  4R30 A;  1YTW A;  4D3Q A;  4QBW A;  1XBO A;  3D1O A;  2QBS A;  2HNP A;  2VEU A;  4QAH A;  4QBE A;  2HC1 A;  2FJN A;  2H4G A;  3S4E A;  5K23 A;  2Y96 A;  2MBC A;  3ZM2 A;  3QCH A;  3QCJ A;  2H03 A;  2B07 A;  4PVG A;  1PXH A;  2QBP A;  2E0T A;  2I6O A;  1Q1M A;  2GWO A;  4Y14 A;  3EMU A;  1AAX A;  2I6P A;  4NWF A;  1OES A;  2H4K A;  2G6Z A;  2H02 A;  1C86 A;  2HY3 A;  5KA0 A;  3BM8 A;  1PTU A;  1M3G A;  3RZ2 A;  5KAC A;  2A3K A;  2PT0 A;  5LXQ B;  1Q6N A;  3OLR A;  1OEM X;  4ICZ A;  1YGU A;  4RI4 A;  3MOW A;  2NLK A;  3S3K A;  3V0J A;  2I42 A;  3V0D A;  2PBN A;  4NND A;  2QCJ A;  2QDM A;  4RI5 A;  4ERC A;  2YDU A;  1JLN A;  3V0E A;  2OZ5 A;  4KYR A;  3QKP A;  3PS5 A;  3ZMQ A;  2G59 A;  3QCE A;  2C46 A;  2BV5 A;  3GXH A;  3V0F A;  1PYN A;  5EHP A;  3I80 A;  5BUG A;  4AZ1 A;  4GE2 A;  2I1Y A;  4JNB A;  2HB1 A;  1LQF A;  4BPC A;  5BZX A;  1OEV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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