2HGFA

Hairpin loop containing domain of hepatocyte growth factor, nmr, minimized average structure
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
97
structure length
97
Chain Sequence
GQRKRRNTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The solution structure of the N-terminal domain of hepatocyte growth factor reveals a potential heparin-binding site.
pubmed doi rcsb
molecule tags Hepatocyte growth factor
source organism Homo sapiens
molecule keywords HEPATOCYTE GROWTH FACTOR
total genus 14
structure length 97
sequence length 97
ec nomenclature
pdb deposition date 1997-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00024 PAN_1 PAN domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 2hgfA00
3ZWZA 5CS1A 1HKYA 2J8LA 3HMSA 5CS3A 1I8NA 5CS5A 2HGFA 4UV6A 1Z40A 5CP9A 5CSQA 2F83A 5I25A 1W81A 2YIPA 2Y8RA 2K13X 4Z09A 3MKPA 1GP9A 3HN4A 4R1AA 5CS9A 4Z0FA 4APLA 5CT1A 4IUAA 1W8KA 3ZLEA 1BHTA 2X2ZA 3HMTA 4R19A 2J8JA 5EOKA 4R1CA 1GMNA 4A5TS 5CT2A 4Z0DA 5COEA 4DURA 2Q8AA 3HMRA 5CT3A 1GMOA 3SP8A 2Q8BA 2YILA 4UAOA 4Z0EA 2LL3A 3SRJA 3SRIA 2QJ4A 2Z8VA 2Z8WA 5EODA 2YIOA 4APMA 1NK1A 1YXEA 4R1BA 2QJ2A 2LL4M
chains in the Genus database with same CATH superfamily
3ZWZA 5CS1A 1HKYA 2J8LA 3HMSA 5CS3A 1I8NA 5CS5A 2HGFA 4UV6A 1Z40A 5CP9A 5CSQA 2F83A 5I25A 1W81A 2YIPA 2Y8RA 2K13X 4Z09A 3MKPA 1GP9A 3HN4A 4R1AA 5CS9A 4Z0FA 4APLA 5CT1A 4YIZA 4IUAA 1W8KA 3ZLEA 1BHTA 2X2ZA 3HMTA 4R19A 2J8JA 5EOKA 4R1CA 1GMNA 4YIVA 4A5TS 5CT2A 4Z0DA 5COEA 4DURA 2Q8AA 3HMRA 5CT3A 1GMOA 3SP8A 2Q8BA 2YILA 4UAOA 4Z0EA 2LL3A 3SRJA 3SRIA 2KL5A 2QJ4A 2Z8VA 2Z8WA 5EODA 2YIOA 4APMA 1NK1A 1YXEA 4R1BA 2QJ2A 2LL4M
chains in the Genus database with same CATH topology
3ZWZA 5CS1A 1HKYA 2J8LA 3HMSA 5CS3A 1I8NA 5CS5A 2HGFA 4UV6A 1Z40A 5CP9A 5CSQA 2F83A 5I25A 1W81A 2YIPA 2Y8RA 2K13X 4Z09A 3MKPA 1GP9A 3HN4A 4R1AA 5CS9A 4Z0FA 4APLA 5CT1A 4YIZA 4IUAA 1W8KA 3ZLEA 1BHTA 2X2ZA 3HMTA 4R19A 2J8JA 5EOKA 4R1CA 1GMNA 4YIVA 4A5TS 5CT2A 4Z0DA 5COEA 4DURA 2Q8AA 3HMRA 5CT3A 1GMOA 3SP8A 2Q8BA 2YILA 4UAOA 4Z0EA 2LL3A 3SRJA 3SRIA 2KL5A 2QJ4A 2Z8VA 2Z8WA 5EODA 2YIOA 4APMA 1NK1A 1YXEA 4R1BA 2QJ2A 2LL4M
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZWZ A;  5CS1 A;  1HKY A;  2J8L A;  3HMS A;  5CS3 A;  1I8N A;  5CS5 A;  2HGF A;  4UV6 A;  1Z40 A;  5CP9 A;  5CSQ A;  2F83 A;  5I25 A;  1W81 A;  2YIP A;  2Y8R A;  2K13 X;  4Z09 A;  3MKP A;  1GP9 A;  3HN4 A;  4R1A A;  5CS9 A;  4Z0F A;  4APL A;  5CT1 A;  4IUA A;  1W8K A;  3ZLE A;  1BHT A;  2X2Z A;  3HMT A;  4R19 A;  2J8J A;  5EOK A;  4R1C A;  1GMN A;  4A5T S;  5CT2 A;  4Z0D A;  5COE A;  4DUR A;  2Q8A A;  3HMR A;  5CT3 A;  1GMO A;  3SP8 A;  2Q8B A;  2YIL A;  4UAO A;  4Z0E A;  2LL3 A;  3SRJ A;  3SRI A;  2QJ4 A;  2Z8V A;  2Z8W A;  5EOD A;  2YIO A;  4APM A;  1NK1 A;  1YXE A;  4R1B A;  2QJ2 A;  2LL4 M; 
#chains in the Genus database with same CATH topology
 3ZWZ A;  5CS1 A;  1HKY A;  2J8L A;  3HMS A;  5CS3 A;  1I8N A;  5CS5 A;  2HGF A;  4UV6 A;  1Z40 A;  5CP9 A;  5CSQ A;  2F83 A;  5I25 A;  1W81 A;  2YIP A;  2Y8R A;  2K13 X;  4Z09 A;  3MKP A;  1GP9 A;  3HN4 A;  4R1A A;  5CS9 A;  4Z0F A;  4APL A;  5CT1 A;  4YIZ A;  4IUA A;  1W8K A;  3ZLE A;  1BHT A;  2X2Z A;  3HMT A;  4R19 A;  2J8J A;  5EOK A;  4R1C A;  1GMN A;  4YIV A;  4A5T S;  5CT2 A;  4Z0D A;  5COE A;  4DUR A;  2Q8A A;  3HMR A;  5CT3 A;  1GMO A;  3SP8 A;  2Q8B A;  2YIL A;  4UAO A;  4Z0E A;  2LL3 A;  3SRJ A;  3SRI A;  2KL5 A;  2QJ4 A;  2Z8V A;  2Z8W A;  5EOD A;  2YIO A;  4APM A;  1NK1 A;  1YXE A;  4R1B A;  2QJ2 A;  2LL4 M; 
#chains in the Genus database with same CATH homology
 3ZWZ A;  5CS1 A;  1HKY A;  2J8L A;  3HMS A;  5CS3 A;  1I8N A;  5CS5 A;  2HGF A;  4UV6 A;  1Z40 A;  5CP9 A;  5CSQ A;  2F83 A;  5I25 A;  1W81 A;  2YIP A;  2Y8R A;  2K13 X;  4Z09 A;  3MKP A;  1GP9 A;  3HN4 A;  4R1A A;  5CS9 A;  4Z0F A;  4APL A;  5CT1 A;  4YIZ A;  4IUA A;  1W8K A;  3ZLE A;  1BHT A;  2X2Z A;  3HMT A;  4R19 A;  2J8J A;  5EOK A;  4R1C A;  1GMN A;  4YIV A;  4A5T S;  5CT2 A;  4Z0D A;  5COE A;  4DUR A;  2Q8A A;  3HMR A;  5CT3 A;  1GMO A;  3SP8 A;  2Q8B A;  2YIL A;  4UAO A;  4Z0E A;  2LL3 A;  3SRJ A;  3SRI A;  2KL5 A;  2QJ4 A;  2Z8V A;  2Z8W A;  5EOD A;  2YIO A;  4APM A;  1NK1 A;  1YXE A;  4R1B A;  2QJ2 A;  2LL4 M; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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