2HH2A

Solution structure of the fourth kh domain of ksrp
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
79
structure length
79
Chain Sequence
GEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation.
pubmed doi rcsb
molecule keywords KH-type splicing regulatory protein
molecule tags Rna binding protein
source organism Homo sapiens
total genus 18
structure length 79
sequence length 79
ec nomenclature
pdb deposition date 2006-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2hh2A00
1ZZIA 1ZTGA 2OPUA 4NBQA 1DT4A 1ZZKA 2CTLA 2AXYA 3AEVB 2HH2A 2HH3A 4B8TA 2ANNA 2JA9A 4QMFB 2OPVA 2JZXA 2PY9A 1VIGA 2CTEA 1ZZJA 2ANRA 1KHMA 1X4MA 4JVHA 1J4WA 2BL5A 2JE6I 2JVZA 2QNDA 5JEAG 2CTJA 2YQRA 4AM3A 4JVYA 2CTFA 4BA1I 4BA2I 2NN6G 4WALA 1X4NA 2DGRA 4AIMA 1WVNA 1VIHA 1EC6A 1J5KA 2Z0SA 3VKEA 2E3UA 1K1GA 3L7ZC 2PQUA 3V69A 2MJHA 2CTMA 5K36G 1TUAA 5C0XG 2P2RA 4LIJA 2FMRA 1DTJA 4WANA 3U1KA 1WE8A 4IFDG 2BA0A 2CPQA 2JEBI 2JEAI 2CTKA 4OO1G
chains in the Genus database with same CATH superfamily
4DUYH 4DV5H 2CWFA 2LTMA 1IBLH 4FJSA 2HH3A 2ANNA 1HNXH 4X64H 4DV4H 4NXNH 2PY9A 1ZZJA 2ANRA 4FJUA 4GKKH 1NXUA 1X4MA 4DR5H 2JE6I 4X66H 3T1HH 4LF8H 1MSZA 2CPMA 1IBKH 4BA2I 4BA1I 1HNWH 3OSSD 4X65H 3QD7X 2G8YA 4OCHA 2Z0SA 5FLXW 1K1GA 2PQUA 3V69A 1XNQH 2CTMA 3J7AK 5K36G 5IT9W 4E9JA 2P2RA 3I0PA 1X0AA 4DV1H 2BA0A 2CPQA 2A1SA 1Z2IA 4H8AA 3EZJA 4B8CD 3GR5A 2CTKA 2JEAI 2UUAH 1J5EH 2CTLA 2UUBH 2M6QA 1XNRH 4JI8H 1S20A 4NZTM 1IBMH 2M8WA 4NZRM 5LMUH 4LF7H 3SB1A 2UXBH 3KDGA 4B8TA 4GKJH 2JA9A 4QMFB 3J80W 2ZM6H 4DV3H 4DV2H 1VIGA 2CTEA 4JI0H 2X06A 4JVHA 1XMQH 1VBIA 1EC6A 2QNDA 4WANA 2CTJA 1WHRA 1I6UA 2NN6G 4EC5A 2LF0A 1X9ZA 2DGRA 3FAUA 4AIMA 2LTLA 3JAMW 2Y3MA 1SEIA 1N33H 2UXDH 4JYAH 4DR1H 3GABA 4LFBH 2CWHA 4DR4H 3U1KA 1WE8A 4DV0H 2JVZA 3OTOH 2JEBI 2UUCH 4OO1G 4JI3H 1FKAH 1V9NA 2D9IA 2OPUA 2K1HA 5DT9A 4K0KH 1ODHA 2O4CA 4LFCH 1F0XA 4JV5H 4JI1H 2VQEH 2E5LH 4B3SH 4OX9H 2OPVA 2JZXA 4YHHH 1HNZH 4NXMH 3GKUA 4JI5H 1N32H 1UG8A 2VKCA 3T1YH 1KHMA 1J4WA 4PDBA 2BL5A 5JEAG 4AM3A 2YQRA 5LMNH 5IWAH 2ZQEA 4WALA 4OD6A 1WVNA 3UOEA 1J5KA 3VKEA 4DUZH 4G08A 2VQFH 3RF2A 4DR6H 5C0XG 1V8CA 4X62H 4LIJA 2PT7G 1DTJA 2UU9H 4JI2H 4LF9H 4LFAH 1N36H 4DR7H 1AN7A 1ZZIA 5A2QW 1ZTGA 4B3RH 1HR0H 4NBQA 1DT4A 1ZZKA 5BR8H 5LL6b 2AXYA 2HHHH 4JI4H 2LRRA 4YY3H 3AEVB 2HH2A 4LF5H 1PQXA 3KDKA 4JI7H 2FPHX 4KHPH 4DR2H 1N34H 4LF4H 1XRHA 1I94H 4JVYA 4LF6H 2FFMA 2CTFA 4JI6H 1X4NA 4B3TH 1FJGH 1VIHA 1XMOH 1S03G 1WTJA 4DR3H 2UXCH 4AQYH 2E3UA 3L7ZC 2F4VH 2MJHA 3J81W 1TUAA 3OETA 2FMRA 4IFDG 4DV7H 4DV6H 4B3MH 3NCVA
chains in the Genus database with same CATH topology
1ZZIA 1ZTGA 2OPUA 4NBQA 1DT4A 1ZZKA 2CTLA 2AXYA 3AEVB 2HH2A 2HH3A 4B8TA 2ANNA 2JA9A 4QMFB 2OPVA 2JZXA 2PY9A 1VIGA 2CTEA 1ZZJA 2ANRA 1KHMA 1X4MA 4JVHA 1J4WA 2BL5A 2JE6I 2JVZA 2QNDA 5JEAG 2CTJA 2YQRA 4AM3A 4JVYA 2CTFA 4BA1I 4BA2I 2NN6G 4WALA 1X4NA 2DGRA 4AIMA 1WVNA 1VIHA 1EC6A 1J5KA 2Z0SA 3VKEA 2E3UA 1K1GA 3L7ZC 2PQUA 3V69A 2MJHA 2CTMA 5K36G 1TUAA 5C0XG 2P2RA 4LIJA 2FMRA 1DTJA 4WANA 3U1KA 1WE8A 4IFDG 2BA0A 2CPQA 2JEBI 2JEAI 2CTKA 4OO1G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZZI A;  1ZTG A;  2OPU A;  4NBQ A;  1DT4 A;  1ZZK A;  2CTL A;  2AXY A;  3AEV B;  2HH2 A;  2HH3 A;  4B8T A;  2ANN A;  2JA9 A;  4QMF B;  2OPV A;  2JZX A;  2PY9 A;  1VIG A;  2CTE A;  1ZZJ A;  2ANR A;  1KHM A;  1X4M A;  4JVH A;  1J4W A;  2BL5 A;  2JE6 I;  2JVZ A;  2QND A;  5JEA G;  2CTJ A;  2YQR A;  4AM3 A;  4JVY A;  2CTF A;  4BA1 I;  4BA2 I;  2NN6 G;  4WAL A;  1X4N A;  2DGR A;  4AIM A;  1WVN A;  1VIH A;  1EC6 A;  1J5K A;  2Z0S A;  3VKE A;  2E3U A;  1K1G A;  3L7Z C;  2PQU A;  3V69 A;  2MJH A;  2CTM A;  5K36 G;  1TUA A;  5C0X G;  2P2R A;  4LIJ A;  2FMR A;  1DTJ A;  4WAN A;  3U1K A;  1WE8 A;  4IFD G;  2BA0 A;  2CPQ A;  2JEB I;  2JEA I;  2CTK A;  4OO1 G; 
#chains in the Genus database with same CATH topology
 4DUY H;  4DV5 H;  2CWF A;  2LTM A;  1IBL H;  4FJS A;  2HH3 A;  2ANN A;  1HNX H;  4X64 H;  4DV4 H;  4NXN H;  2PY9 A;  1ZZJ A;  2ANR A;  4FJU A;  4GKK H;  1NXU A;  1X4M A;  4DR5 H;  2JE6 I;  4X66 H;  3T1H H;  4LF8 H;  1MSZ A;  2CPM A;  1IBK H;  4BA2 I;  4BA1 I;  1HNW H;  3OSS D;  4X65 H;  3QD7 X;  2G8Y A;  4OCH A;  2Z0S A;  5FLX W;  1K1G A;  2PQU A;  3V69 A;  1XNQ H;  2CTM A;  3J7A K;  5K36 G;  5IT9 W;  4E9J A;  2P2R A;  3I0P A;  1X0A A;  4DV1 H;  2BA0 A;  2CPQ A;  2A1S A;  1Z2I A;  4H8A A;  3EZJ A;  4B8C D;  3GR5 A;  2CTK A;  2JEA I;  2UUA H;  1J5E H;  2CTL A;  2UUB H;  2M6Q A;  1XNR H;  4JI8 H;  1S20 A;  4NZT M;  1IBM H;  2M8W A;  4NZR M;  5LMU H;  4LF7 H;  3SB1 A;  2UXB H;  3KDG A;  4B8T A;  4GKJ H;  2JA9 A;  4QMF B;  3J80 W;  2ZM6 H;  4DV3 H;  4DV2 H;  1VIG A;  2CTE A;  4JI0 H;  2X06 A;  4JVH A;  1XMQ H;  1VBI A;  1EC6 A;  2QND A;  4WAN A;  2CTJ A;  1WHR A;  1I6U A;  2NN6 G;  4EC5 A;  2LF0 A;  1X9Z A;  2DGR A;  3FAU A;  4AIM A;  2LTL A;  3JAM W;  2Y3M A;  1SEI A;  1N33 H;  2UXD H;  4JYA H;  4DR1 H;  3GAB A;  4LFB H;  2CWH A;  4DR4 H;  3U1K A;  1WE8 A;  4DV0 H;  2JVZ A;  3OTO H;  2JEB I;  2UUC H;  4OO1 G;  4JI3 H;  1FKA H;  1V9N A;  2D9I A;  2OPU A;  2K1H A;  5DT9 A;  4K0K H;  1ODH A;  2O4C A;  4LFC H;  1F0X A;  4JV5 H;  4JI1 H;  2VQE H;  2E5L H;  4B3S H;  4OX9 H;  2OPV A;  2JZX A;  4YHH H;  1HNZ H;  4NXM H;  3GKU A;  4JI5 H;  1N32 H;  1UG8 A;  2VKC A;  3T1Y H;  1KHM A;  1J4W A;  4PDB A;  2BL5 A;  5JEA G;  4AM3 A;  2YQR A;  5LMN H;  5IWA H;  2ZQE A;  4WAL A;  4OD6 A;  1WVN A;  3UOE A;  1J5K A;  3VKE A;  4DUZ H;  4G08 A;  2VQF H;  3RF2 A;  4DR6 H;  5C0X G;  1V8C A;  4X62 H;  4LIJ A;  2PT7 G;  1DTJ A;  2UU9 H;  4JI2 H;  4LF9 H;  4LFA H;  1N36 H;  4DR7 H;  1AN7 A;  1ZZI A;  5A2Q W;  1ZTG A;  4B3R H;  1HR0 H;  4NBQ A;  1DT4 A;  1ZZK A;  5BR8 H;  5LL6 b;  2AXY A;  2HHH H;  4JI4 H;  2LRR A;  4YY3 H;  3AEV B;  2HH2 A;  4LF5 H;  1PQX A;  3KDK A;  4JI7 H;  2FPH X;  4KHP H;  4DR2 H;  1N34 H;  4LF4 H;  1XRH A;  1I94 H;  4JVY A;  4LF6 H;  2FFM A;  2CTF A;  4JI6 H;  1X4N A;  4B3T H;  1FJG H;  1VIH A;  1XMO H;  1S03 G;  1WTJ A;  4DR3 H;  2UXC H;  4AQY H;  2E3U A;  3L7Z C;  2F4V H;  2MJH A;  3J81 W;  1TUA A;  3OET A;  2FMR A;  4IFD G;  4DV7 H;  4DV6 H;  4B3M H;  3NCV A; 
#chains in the Genus database with same CATH homology
 1ZZI A;  1ZTG A;  2OPU A;  4NBQ A;  1DT4 A;  1ZZK A;  2CTL A;  2AXY A;  3AEV B;  2HH2 A;  2HH3 A;  4B8T A;  2ANN A;  2JA9 A;  4QMF B;  2OPV A;  2JZX A;  2PY9 A;  1VIG A;  2CTE A;  1ZZJ A;  2ANR A;  1KHM A;  1X4M A;  4JVH A;  1J4W A;  2BL5 A;  2JE6 I;  2JVZ A;  2QND A;  5JEA G;  2CTJ A;  2YQR A;  4AM3 A;  4JVY A;  2CTF A;  4BA1 I;  4BA2 I;  2NN6 G;  4WAL A;  1X4N A;  2DGR A;  4AIM A;  1WVN A;  1VIH A;  1EC6 A;  1J5K A;  2Z0S A;  3VKE A;  2E3U A;  1K1G A;  3L7Z C;  2PQU A;  3V69 A;  2MJH A;  2CTM A;  5K36 G;  1TUA A;  5C0X G;  2P2R A;  4LIJ A;  2FMR A;  1DTJ A;  4WAN A;  3U1K A;  1WE8 A;  4IFD G;  2BA0 A;  2CPQ A;  2JEB I;  2JEA I;  2CTK A;  4OO1 G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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