2HH3A

Solution structure of the third kh domain of ksrp
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
71
structure length
71
Chain Sequence
GIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords KH-type splicing regulatory protein
total genus 18
structure length 71
sequence length 71
ec nomenclature
pdb deposition date 2006-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2hh3A00
4AM3A 4OO1G 4WALA 2CTKA 4BA1I 4AIMA 2FMRA 4B8TA 1ZZJA 2ANRA 2MJHA 3AEVB 5JEAG 1X4MA 2PY9A 2CTLA 2QNDA 2CTJA 1ZZIA 2CTMA 2E3UA 1EC6A 1K1GA 3V69A 4BA2I 1TUAA 1WVNA 1ZTGA 4IFDG 3VKEA 5K36G 1ZZKA 2JEAI 1DT4A 2BA0A 2Z0SA 2JE6I 1DTJA 2OPUA 2OPVA 3U1KA 4QMFB 1J4WA 2JVZA 4LIJA 3L7ZC 2ANNA 4WANA 2BL5A 2DGRA 2HH2A 2JEBI 4JVYA 2CTEA 2HH3A 2P2RA 1VIHA 5C0XG 2CPQA 4NBQA 1KHMA 1WE8A 2PQUA 1X4NA 1VIGA 2JA9A 2AXYA 2JZXA 2YQRA 1J5KA 2CTFA 4JVHA 2NN6G
chains in the Genus database with same CATH superfamily
1N36H 2PT7G 4AM3A 4OO1G 4WALA 4DV6H 4JI6H 4BA1I 5IWAH 2ANRA 4LFAH 3SB1A 4DR5H 2UU9H 2LRRA 2CTLA 4X64H 3J80W 4OCHA 4FJUA 2CTJA 4JI7H 1K1GA 5LMUH 3T1HH 4LF4H 4NXMH 1TUAA 4YHHH 1DT4A 2BA0A 3OETA 3J81W 4DR6H 4DR3H 5IT9W 3T1YH 3GR5A 2E5LH 2HHHH 4DR7H 2FFMA 2HH2A 2JEBI 1Z2IA 2VQFH 4B3SH 1N33H 2P2RA 1VBIA 5LMNH 4DUZH 2O4CA 1WE8A 4K0KH 2K1HA 2G8YA 1J5KA 4OX9H 2UUBH 4DV0H 1F0XA 1WTJA 1ODHA 1NXUA 2UUCH 3FAUA 4LF9H 4JYAH 2CTKA 1HR0H 1IBLH 2FMRA 3GABA 1N32H 4JI3H 1UG8A 4LFBH 4JI0H 2M6QA 4E9JA 3UOEA 2QNDA 1ZZIA 1SEIA 1XNQH 3JAMW 2UXDH 4NZRM 1S03G 1ZTGA 4DV3H 1I94H 3VKEA 4LF5H 3GKUA 2A1SA 2OPVA 3U1KA 3KDKA 1HNZH 1J4WA 3L7ZC 3OTOH 2CPMA 1S20A 4DV1H 2UXBH 2DGRA 2LTLA 5FLXW 1XNRH 4JVYA 1HNWH 3J7AK 5C0XG 1KHMA 2X06A 2PQUA 1X4NA 2JA9A 2JZXA 2CTFA 4B3MH 2NN6G 4LF8H 1V8CA 4LFCH 4FJSA 1IBKH 4DR4H 1AN7A 2Y3MA 4DR2H 4B8TA 1ZZJA 5JEAG 4B3RH 2UXCH 2CTMA 3OSSD 2ZM6H 3V69A 4BA2I 3NCVA 5K36G 1WVNA 4NZTM 1X0AA 2JEAI 4JI5H 1DTJA 4YY3H 1V9NA 2JVZA 4NXNH 2CWFA 5A2QW 4DV5H 4JV5H 3KDGA 2VQEH 1FJGH 4X66H 4JI8H 3QD7X 2HH3A 4DV7H 1VIHA 3EZJA 4JI1H 4NBQA 4OD6A 2F4VH 1I6UA 4B8CD 4LF7H 4X65H 2AXYA 2LF0A 1J5EH 4JVHA 2CTEA 1FKAH 4GKKH 5BR8H 1XMOH 1PQXA 4DR1H 1X9ZA 4AIMA 2MJHA 3AEVB 5LL6b 1X4MA 2PY9A 2VKCA 2ZQEA 4LF6H 2E3UA 1N34H 1EC6A 2UUAH 4IFDG 1XMQH 1WHRA 2FPHX 1ZZKA 4GKJH 4KHPH 5DT9A 2Z0SA 2JE6I 4EC5A 2OPUA 4AQYH 2LTMA 4QMFB 1IBMH 4B3TH 4LIJA 1HNXH 2ANNA 1XRHA 4DUYH 4WANA 2D9IA 2BL5A 4G08A 1MSZA 2M8WA 4X62H 4H8AA 2CPQA 4DV2H 4DV4H 3RF2A 4PDBA 1VIGA 3I0PA 2YQRA 2CWHA 4JI2H 4JI4H
chains in the Genus database with same CATH topology
4AM3A 4OO1G 4WALA 2CTKA 4BA1I 4AIMA 2FMRA 4B8TA 1ZZJA 2ANRA 2MJHA 3AEVB 5JEAG 1X4MA 2PY9A 2CTLA 2QNDA 2CTJA 1ZZIA 2CTMA 2E3UA 1EC6A 1K1GA 3V69A 4BA2I 1TUAA 1WVNA 1ZTGA 4IFDG 3VKEA 5K36G 1ZZKA 2JEAI 1DT4A 2BA0A 2Z0SA 2JE6I 1DTJA 2OPUA 2OPVA 3U1KA 4QMFB 1J4WA 2JVZA 4LIJA 3L7ZC 2ANNA 4WANA 2BL5A 2DGRA 2HH2A 2JEBI 4JVYA 2CTEA 2HH3A 2P2RA 1VIHA 5C0XG 2CPQA 4NBQA 1KHMA 1WE8A 2PQUA 1X4NA 1VIGA 2JA9A 2AXYA 2JZXA 2YQRA 1J5KA 2CTFA 4JVHA 2NN6G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AM3 A;  4OO1 G;  4WAL A;  2CTK A;  4BA1 I;  4AIM A;  2FMR A;  4B8T A;  1ZZJ A;  2ANR A;  2MJH A;  3AEV B;  5JEA G;  1X4M A;  2PY9 A;  2CTL A;  2QND A;  2CTJ A;  1ZZI A;  2CTM A;  2E3U A;  1EC6 A;  1K1G A;  3V69 A;  4BA2 I;  1TUA A;  1WVN A;  1ZTG A;  4IFD G;  3VKE A;  5K36 G;  1ZZK A;  2JEA I;  1DT4 A;  2BA0 A;  2Z0S A;  2JE6 I;  1DTJ A;  2OPU A;  2OPV A;  3U1K A;  4QMF B;  1J4W A;  2JVZ A;  4LIJ A;  3L7Z C;  2ANN A;  4WAN A;  2BL5 A;  2DGR A;  2HH2 A;  2JEB I;  4JVY A;  2CTE A;  2HH3 A;  2P2R A;  1VIH A;  5C0X G;  2CPQ A;  4NBQ A;  1KHM A;  1WE8 A;  2PQU A;  1X4N A;  1VIG A;  2JA9 A;  2AXY A;  2JZX A;  2YQR A;  1J5K A;  2CTF A;  4JVH A;  2NN6 G; 
#chains in the Genus database with same CATH topology
 1N36 H;  2PT7 G;  4AM3 A;  4OO1 G;  4WAL A;  4DV6 H;  4JI6 H;  4BA1 I;  5IWA H;  2ANR A;  4LFA H;  3SB1 A;  4DR5 H;  2UU9 H;  2LRR A;  2CTL A;  4X64 H;  3J80 W;  4OCH A;  4FJU A;  2CTJ A;  4JI7 H;  1K1G A;  5LMU H;  3T1H H;  4LF4 H;  4NXM H;  1TUA A;  4YHH H;  1DT4 A;  2BA0 A;  3OET A;  3J81 W;  4DR6 H;  4DR3 H;  5IT9 W;  3T1Y H;  3GR5 A;  2E5L H;  2HHH H;  4DR7 H;  2FFM A;  2HH2 A;  2JEB I;  1Z2I A;  2VQF H;  4B3S H;  1N33 H;  2P2R A;  1VBI A;  5LMN H;  4DUZ H;  2O4C A;  1WE8 A;  4K0K H;  2K1H A;  2G8Y A;  1J5K A;  4OX9 H;  2UUB H;  4DV0 H;  1F0X A;  1WTJ A;  1ODH A;  1NXU A;  2UUC H;  3FAU A;  4LF9 H;  4JYA H;  2CTK A;  1HR0 H;  1IBL H;  2FMR A;  3GAB A;  1N32 H;  4JI3 H;  1UG8 A;  4LFB H;  4JI0 H;  2M6Q A;  4E9J A;  3UOE A;  2QND A;  1ZZI A;  1SEI A;  1XNQ H;  3JAM W;  2UXD H;  4NZR M;  1S03 G;  1ZTG A;  4DV3 H;  1I94 H;  3VKE A;  4LF5 H;  3GKU A;  2A1S A;  2OPV A;  3U1K A;  3KDK A;  1HNZ H;  1J4W A;  3L7Z C;  3OTO H;  2CPM A;  1S20 A;  4DV1 H;  2UXB H;  2DGR A;  2LTL A;  5FLX W;  1XNR H;  4JVY A;  1HNW H;  3J7A K;  5C0X G;  1KHM A;  2X06 A;  2PQU A;  1X4N A;  2JA9 A;  2JZX A;  2CTF A;  4B3M H;  2NN6 G;  4LF8 H;  1V8C A;  4LFC H;  4FJS A;  1IBK H;  4DR4 H;  1AN7 A;  2Y3M A;  4DR2 H;  4B8T A;  1ZZJ A;  5JEA G;  4B3R H;  2UXC H;  2CTM A;  3OSS D;  2ZM6 H;  3V69 A;  4BA2 I;  3NCV A;  5K36 G;  1WVN A;  4NZT M;  1X0A A;  2JEA I;  4JI5 H;  1DTJ A;  4YY3 H;  1V9N A;  2JVZ A;  4NXN H;  2CWF A;  5A2Q W;  4DV5 H;  4JV5 H;  3KDG A;  2VQE H;  1FJG H;  4X66 H;  4JI8 H;  3QD7 X;  2HH3 A;  4DV7 H;  1VIH A;  3EZJ A;  4JI1 H;  4NBQ A;  4OD6 A;  2F4V H;  1I6U A;  4B8C D;  4LF7 H;  4X65 H;  2AXY A;  2LF0 A;  1J5E H;  4JVH A;  2CTE A;  1FKA H;  4GKK H;  5BR8 H;  1XMO H;  1PQX A;  4DR1 H;  1X9Z A;  4AIM A;  2MJH A;  3AEV B;  5LL6 b;  1X4M A;  2PY9 A;  2VKC A;  2ZQE A;  4LF6 H;  2E3U A;  1N34 H;  1EC6 A;  2UUA H;  4IFD G;  1XMQ H;  1WHR A;  2FPH X;  1ZZK A;  4GKJ H;  4KHP H;  5DT9 A;  2Z0S A;  2JE6 I;  4EC5 A;  2OPU A;  4AQY H;  2LTM A;  4QMF B;  1IBM H;  4B3T H;  4LIJ A;  1HNX H;  2ANN A;  1XRH A;  4DUY H;  4WAN A;  2D9I A;  2BL5 A;  4G08 A;  1MSZ A;  2M8W A;  4X62 H;  4H8A A;  2CPQ A;  4DV2 H;  4DV4 H;  3RF2 A;  4PDB A;  1VIG A;  3I0P A;  2YQR A;  2CWH A;  4JI2 H;  4JI4 H; 
#chains in the Genus database with same CATH homology
 4AM3 A;  4OO1 G;  4WAL A;  2CTK A;  4BA1 I;  4AIM A;  2FMR A;  4B8T A;  1ZZJ A;  2ANR A;  2MJH A;  3AEV B;  5JEA G;  1X4M A;  2PY9 A;  2CTL A;  2QND A;  2CTJ A;  1ZZI A;  2CTM A;  2E3U A;  1EC6 A;  1K1G A;  3V69 A;  4BA2 I;  1TUA A;  1WVN A;  1ZTG A;  4IFD G;  3VKE A;  5K36 G;  1ZZK A;  2JEA I;  1DT4 A;  2BA0 A;  2Z0S A;  2JE6 I;  1DTJ A;  2OPU A;  2OPV A;  3U1K A;  4QMF B;  1J4W A;  2JVZ A;  4LIJ A;  3L7Z C;  2ANN A;  4WAN A;  2BL5 A;  2DGR A;  2HH2 A;  2JEB I;  4JVY A;  2CTE A;  2HH3 A;  2P2R A;  1VIH A;  5C0X G;  2CPQ A;  4NBQ A;  1KHM A;  1WE8 A;  2PQU A;  1X4N A;  1VIG A;  2JA9 A;  2AXY A;  2JZX A;  2YQR A;  1J5K A;  2CTF A;  4JVH A;  2NN6 G; 
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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