2HI8X

Human formylglycine generating enzyme, c336s mutant, bromide co-crystallization
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
286
structure length
274
Chain Sequence
LAHSKMVPIPAGVFTMGTDDPQIKQDGEAPARRVTIDAFYMDAYEVSNTEFEKFVNSTGYLTEAEKFGDSFVFEGMLAAAPWWLPVKGANWRHPEGPDSTILHRPDHPVLHVSWNDAVAYCTWAGKRLPTEAEWEYSCRGGLHNRLFPWGNKLQPKGQHYANIWQGEFPVTNTGEDGFQGTAPVDAFPPNGYGLYNIVGNAWEWTSDWWTVHHSVEETLNPKGPPSGKDRVKKGGSYMSHRSYCYRYRCAARSQNTPDSSASNLGFRCAADRLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase activator, protein binding
molecule keywords Sulfatase-modifying factor 1
publication title Probing the oxygen-binding site of the human formylglycine-generating enzyme using halide ions.
pubmed doi rcsb
source organism Homo sapiens
total genus 79
structure length 274
sequence length 286
ec nomenclature ec 1.8.3.7: Formylglycine-generating enzyme.
pdb deposition date 2006-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF03781 FGE-sulfatase Sulfatase-modifying factor enzyme 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1580.10 Alpha Beta Alpha-Beta Complex paralog of FGE (formylglycine-generating enzyme) paralog of FGE (formylglycine-generating enzyme) 2hi8X00
1YU3A 1Y1FX 1Y1EX 2IOUA 1YU0A 1Y1JX 1YU1A 2AIJX 1YU2A 1Y1IX 1Y1GX 1Z70X 1Y1HX 1YU4A 2HIBX 2AFYX 2AIIX 2AIKX 2Y3CA 1Y4JA 2HI8X 2AFTX 2Q17A
chains in the Genus database with same CATH superfamily
1YU3A 1Y1FX 1Y1EX 2IOUA 1YU0A 1Y1JX 1YU1A 2AIJX 1YU2A 1Y1IX 1Y1GX 1Z70X 1Y1HX 1YU4A 2HIBX 2AFYX 2AIIX 2AIKX 2Y3CA 1Y4JA 2HI8X 2AFTX 2Q17A
chains in the Genus database with same CATH topology
1YU3A 1Y1FX 1Y1EX 2IOUA 1YU0A 1Y1JX 1YU1A 2AIJX 1YU2A 1Y1IX 1Y1GX 1Z70X 1Y1HX 1YU4A 2HIBX 2AFYX 2AIIX 2AIKX 2Y3CA 1Y4JA 2HI8X 2AFTX 2Q17A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YU3 A;  1Y1F X;  1Y1E X;  2IOU A;  1YU0 A;  1Y1J X;  1YU1 A;  2AIJ X;  1YU2 A;  1Y1I X;  1Y1G X;  1Z70 X;  1Y1H X;  1YU4 A;  2HIB X;  2AFY X;  2AII X;  2AIK X;  2Y3C A;  1Y4J A;  2HI8 X;  2AFT X;  2Q17 A; 
#chains in the Genus database with same CATH topology
 1YU3 A;  1Y1F X;  1Y1E X;  2IOU A;  1YU0 A;  1Y1J X;  1YU1 A;  2AIJ X;  1YU2 A;  1Y1I X;  1Y1G X;  1Z70 X;  1Y1H X;  1YU4 A;  2HIB X;  2AFY X;  2AII X;  2AIK X;  2Y3C A;  1Y4J A;  2HI8 X;  2AFT X;  2Q17 A; 
#chains in the Genus database with same CATH homology
 1YU3 A;  1Y1F X;  1Y1E X;  2IOU A;  1YU0 A;  1Y1J X;  1YU1 A;  2AIJ X;  1YU2 A;  1Y1I X;  1Y1G X;  1Z70 X;  1Y1H X;  1YU4 A;  2HIB X;  2AFY X;  2AII X;  2AIK X;  2Y3C A;  1Y4J A;  2HI8 X;  2AFT X;  2Q17 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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