2HMLA

Crystal structure of the naphthalene 1,2-dioxygenase f352v mutant bound to phenanthrene.
Total Genus 162
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
162
sequence length
446
structure length
446
Chain Sequence
MNYNNKILVSESGLSQKHLIHGDEELFQHELKTIFARNWLFLTHDSLIPAPGDYVTAKMGIDEVIVSRQNDGSIRAFLNVCRHRGKTLVSVEAGNAKGFVCSYHGWGFGSNGELQSVPFEKDLYGESLNKKCLGLKEVARVESFHGFIYGCFDQEAPPLMDYLGDAAWYLEPMFKHSGGLELVGPPGKVVIKANWKAPAENFVGDAYHVGWTHASSLRSGESIFSSLAGNAALPPEGAGLQMTSKYGSGMGVLWDGYSGVHSADLVPELMAFGGAKQERLNKEIGDVRARIYRSHLNCTVFPNNSMLTCSGVFKVWNPIDANTTEVWTYAIVEKDMPEDLKRRLADSVQRTVGPAGFWESDDNDNMETASQNGKKYQSRDSDLLSNLGFGEDVYGDAVYPGVVGKSAIGETSYRGFYRAYQAHVSSSNWAEFEHASSTWHTELTKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for regioselectivity and stereoselectivity of product formation by naphthalene 1,2-dioxygenase.
pubmed doi rcsb
source organism Pseudomonas sp.
molecule tags Oxidoreductase
molecule keywords Naphthalene 1,2-dioxygenase alpha subunit
total genus 162
structure length 446
sequence length 446
ec nomenclature ec 1.14.12.12: Naphthalene 1,2-dioxygenase.
pdb deposition date 2006-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00355 Rieske Rieske [2Fe-2S] domain
A PF00848 Ring_hydroxyl_A Ring hydroxylating alpha subunit (catalytic domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.102.10.10 Mainly Beta 3-layer Sandwich Rieske Iron-sulfur Protein Rieske [2Fe-2S] iron-sulphur domain 2hmlA02
3.90.380.10 Alpha Beta Alpha-Beta Complex Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 2hmlA01
2ZYLA 1Q90C 1P84E 4NBCA 4NBGA 4AIVA 1JM1A 2B24A 4NB8D 4EMJB 2YFLA 2D2CD 1O7NA 3VMHD 3H1IE 2HMJA 1NTZE 2E74D 4QURA 3AZCA 3CX5E 1BE3E 1O7PA 3GTEA 4H13D 2BMQA 3L74E 1O7MA 4NB9D 4NBAA 4HKVA 2YIUC 2HMKA 3GCFA 3L72E 1PP9E 2FYUE 3L71E 3GCEA 2NVEA 2NVFA 3GKEA 4NBHA 1EG9A 2NVGA 2DE5D 1L0LE 4NBBA 4NBCD 4NBHD 4QDCA 2YVJB 4HM3A 3GZXA 4NBAD 5KLVE 4NB9A 4HM0A 1FQTA 2E75D 3VCAA 2XRXA 2DE5A 1Z02A 3DQYA 3H1LE 1G8KB 2HMOA 1RFSA 3VMID 2DE7A 3H1JE 2NUKA 4NBFD 3VCPA 1NYKA 3C0DA 1G8JB 2JZAA 1NTKE 3CWBE 1SQPE 4HJLA 2I7FA 4NB8A 1EZVE 2ZT9D 3GOBA 4HM4A 3VMGA 3GKQA 4OGQD 2IBZE 1KB9E 4HM5A 2HMNA 1UUVA 2B1XA 1O7GA 3TGUE 3L70E 4QUQA 2QPZA 1VM9A 2BMRA 2Q3WA 4QDDA 4NBGD 1ZRTE 1ULIA 2XSOA 3EQQA 3H1KE 5BOKA 1UUWA 5CXMA 1SQVE 4H44D 4HM8A 3GZYA 3L75E 1RIEA 4P1BH 2GBWA 3BCCE 5AEUA 2YFJA 2HMMA 2YFIA 3D89A 3VMIA 2XSHA 2GBXA 2QJPC 4QDFB 3L73E 2DE6A 4NBBD 5HL4A 3GB4A 1NU1E 1NDOA 1NTME 1O7WA 3N0QA 1VF5D 1BCCE 1VCKA 2XR8A 3VMGD 3FOUA 1WQLA 1SQQE 5AEWA 2NWFA 2QJYC 4HM6A 2FYNC 3VMHA 1SQXE 4NBFA 3GL2A 3CXHE 4P1CH 2DE6D 4QCKA 1PPJE 4HM2A 1L0NE 2DE7D 2HMLA 2A06E 3EN1A 3GL0A 3H1HE 2QJKC 1Z01A 4AAYB 2JO6A 4QUPA 1KYOE 4HM1A 2BMOA 1O7HA 4U3FE 4HM7A 1WW9A 1Z03A 4PV1D 2E76D 4NBEA 1ULJA 2E4QA 1SJGA 2CKFA 4QDFA 4NBED 2E4PA 2NUMA 4NBDA 4PD4E 3GTSA 5KLIC 4H0LD 5KKZC 2BCCE 4NBDD 1SQBE
chains in the Genus database with same CATH superfamily
2ZYLA 1Q90C 1P84E 4NBCA 4NBGA 4AIVA 1JM1A 2B24A 4NB8D 4EMJB 2YFLA 2D2CD 1O7NA 3VMHD 3H1IE 2HMJA 1NTZE 2E74D 4QURA 3AZCA 3CX5E 1BE3E 1O7PA 3GTEA 4H13D 2BMQA 3L74E 1O7MA 4NB9D 4NBAA 4HKVA 2YIUC 2HMKA 3GCFA 3L72E 1PP9E 2FYUE 3L71E 3GCEA 2NVEA 2NVFA 3GKEA 4NBHA 1EG9A 2NVGA 2DE5D 1L0LE 4NBBA 4NBCD 4NBHD 4QDCA 2YVJB 4HM3A 3GZXA 4NBAD 5KLVE 4NB9A 4HM0A 1FQTA 2E75D 3VCAA 2XRXA 2DE5A 1Z02A 3DQYA 3H1LE 1G8KB 2HMOA 1RFSA 3VMID 2DE7A 3H1JE 2NUKA 4NBFD 3VCPA 1NYKA 3C0DA 1G8JB 2JZAA 1NTKE 3CWBE 1SQPE 4HJLA 2I7FA 4NB8A 1EZVE 2ZT9D 3GOBA 4HM4A 3VMGA 3GKQA 4OGQD 2IBZE 1KB9E 4HM5A 2HMNA 1UUVA 2B1XA 1O7GA 3TGUE 3L70E 4QUQA 2QPZA 1VM9A 2BMRA 2Q3WA 4QDDA 4NBGD 1ZRTE 1ULIA 2XSOA 3EQQA 3H1KE 5BOKA 1UUWA 5CXMA 1SQVE 4H44D 4HM8A 3GZYA 3L75E 1RIEA 4P1BH 2GBWA 3BCCE 5AEUA 2YFJA 2HMMA 2YFIA 3D89A 3VMIA 2XSHA 2GBXA 2QJPC 4QDFB 3L73E 2DE6A 4NBBD 5HL4A 3GB4A 1NU1E 1NDOA 1NTME 1O7WA 3N0QA 1VF5D 1BCCE 1VCKA 2XR8A 3VMGD 3FOUA 1WQLA 1SQQE 5AEWA 2NWFA 2QJYC 4HM6A 2FYNC 3VMHA 1SQXE 4NBFA 3GL2A 3CXHE 4P1CH 2DE6D 4QCKA 1PPJE 4HM2A 1L0NE 2DE7D 2HMLA 2A06E 3EN1A 3GL0A 3H1HE 2QJKC 1Z01A 4AAYB 2JO6A 4QUPA 1KYOE 4HM1A 2BMOA 1O7HA 4U3FE 4HM7A 1WW9A 1Z03A 4PV1D 2E76D 4NBEA 1ULJA 2E4QA 1SJGA 2CKFA 4QDFA 4NBED 2E4PA 2NUMA 4NBDA 4PD4E 3GTSA 5KLIC 4H0LD 5KKZC 2BCCE 4NBDD 1SQBE
chains in the Genus database with same CATH topology
2ZYLA 1Q90C 1P84E 4NBCA 4NBGA 4AIVA 1JM1A 2B24A 4NB8D 4EMJB 2YFLA 2D2CD 1O7NA 3VMHD 3H1IE 2HMJA 1NTZE 2E74D 4QURA 3AZCA 3CX5E 1BE3E 1O7PA 3GTEA 4H13D 2BMQA 3L74E 1O7MA 4NB9D 4NBAA 4HKVA 2YIUC 2HMKA 3GCFA 3L72E 1PP9E 2FYUE 3L71E 3GCEA 2NVEA 2NVFA 3GKEA 4NBHA 1EG9A 2NVGA 2DE5D 1L0LE 4NBBA 4NBCD 4NBHD 4QDCA 2YVJB 4HM3A 3GZXA 4NBAD 5KLVE 4NB9A 4HM0A 1FQTA 2E75D 3VCAA 2XRXA 2DE5A 1Z02A 3DQYA 3H1LE 1G8KB 2HMOA 1RFSA 3VMID 2DE7A 3H1JE 2NUKA 4NBFD 3VCPA 1NYKA 3C0DA 1G8JB 2JZAA 1NTKE 3CWBE 1SQPE 4HJLA 2I7FA 4NB8A 1EZVE 2ZT9D 3GOBA 4HM4A 3VMGA 3GKQA 4OGQD 2IBZE 1KB9E 4HM5A 2HMNA 1UUVA 2B1XA 1O7GA 3TGUE 3L70E 4QUQA 2QPZA 1VM9A 2BMRA 2Q3WA 4QDDA 4NBGD 1ZRTE 1ULIA 2XSOA 3EQQA 3H1KE 5BOKA 1UUWA 5CXMA 1SQVE 4H44D 4HM8A 3GZYA 3L75E 1RIEA 4P1BH 2GBWA 3BCCE 5AEUA 2YFJA 2HMMA 2YFIA 3D89A 3VMIA 2XSHA 2GBXA 2QJPC 4QDFB 3L73E 2DE6A 4NBBD 5HL4A 3GB4A 1NU1E 1NDOA 1NTME 1O7WA 3N0QA 1VF5D 1BCCE 1VCKA 2XR8A 3VMGD 3FOUA 1WQLA 1SQQE 5AEWA 2NWFA 2QJYC 4HM6A 2FYNC 3VMHA 1SQXE 4NBFA 3GL2A 3CXHE 4P1CH 2DE6D 4QCKA 1PPJE 4HM2A 1L0NE 2DE7D 2HMLA 2A06E 3EN1A 3GL0A 3H1HE 2QJKC 1Z01A 4AAYB 2JO6A 4QUPA 1KYOE 4HM1A 2BMOA 1O7HA 4U3FE 4HM7A 1WW9A 1Z03A 4PV1D 2E76D 4NBEA 1ULJA 2E4QA 1SJGA 2CKFA 4QDFA 4NBED 2E4PA 2NUMA 4NBDA 4PD4E 3GTSA 5KLIC 4H0LD 5KKZC 2BCCE 4NBDD 1SQBE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZYL A;  1Q90 C;  1P84 E;  4NBC A;  4NBG A;  4AIV A;  1JM1 A;  2B24 A;  4NB8 D;  4EMJ B;  2YFL A;  2D2C D;  1O7N A;  3VMH D;  3H1I E;  2HMJ A;  1NTZ E;  2E74 D;  4QUR A;  3AZC A;  3CX5 E;  1BE3 E;  1O7P A;  3GTE A;  4H13 D;  2BMQ A;  3L74 E;  1O7M A;  4NB9 D;  4NBA A;  4HKV A;  2YIU C;  2HMK A;  3GCF A;  3L72 E;  1PP9 E;  2FYU E;  3L71 E;  3GCE A;  2NVE A;  2NVF A;  3GKE A;  4NBH A;  1EG9 A;  2NVG A;  2DE5 D;  1L0L E;  4NBB A;  4NBC D;  4NBH D;  4QDC A;  2YVJ B;  4HM3 A;  3GZX A;  4NBA D;  5KLV E;  4NB9 A;  4HM0 A;  1FQT A;  2E75 D;  3VCA A;  2XRX A;  2DE5 A;  1Z02 A;  3DQY A;  3H1L E;  1G8K B;  2HMO A;  1RFS A;  3VMI D;  2DE7 A;  3H1J E;  2NUK A;  4NBF D;  3VCP A;  1NYK A;  3C0D A;  1G8J B;  2JZA A;  1NTK E;  3CWB E;  1SQP E;  4HJL A;  2I7F A;  4NB8 A;  1EZV E;  2ZT9 D;  3GOB A;  4HM4 A;  3VMG A;  3GKQ A;  4OGQ D;  2IBZ E;  1KB9 E;  4HM5 A;  2HMN A;  1UUV A;  2B1X A;  1O7G A;  3TGU E;  3L70 E;  4QUQ A;  2QPZ A;  1VM9 A;  2BMR A;  2Q3W A;  4QDD A;  4NBG D;  1ZRT E;  1ULI A;  2XSO A;  3EQQ A;  3H1K E;  5BOK A;  1UUW A;  5CXM A;  1SQV E;  4H44 D;  4HM8 A;  3GZY A;  3L75 E;  1RIE A;  4P1B H;  2GBW A;  3BCC E;  5AEU A;  2YFJ A;  2HMM A;  2YFI A;  3D89 A;  3VMI A;  2XSH A;  2GBX A;  2QJP C;  4QDF B;  3L73 E;  2DE6 A;  4NBB D;  5HL4 A;  3GB4 A;  1NU1 E;  1NDO A;  1NTM E;  1O7W A;  3N0Q A;  1VF5 D;  1BCC E;  1VCK A;  2XR8 A;  3VMG D;  3FOU A;  1WQL A;  1SQQ E;  5AEW A;  2NWF A;  2QJY C;  4HM6 A;  2FYN C;  3VMH A;  1SQX E;  4NBF A;  3GL2 A;  3CXH E;  4P1C H;  2DE6 D;  4QCK A;  1PPJ E;  4HM2 A;  1L0N E;  2DE7 D;  2HML A;  2A06 E;  3EN1 A;  3GL0 A;  3H1H E;  2QJK C;  1Z01 A;  4AAY B;  2JO6 A;  4QUP A;  1KYO E;  4HM1 A;  2BMO A;  1O7H A;  4U3F E;  4HM7 A;  1WW9 A;  1Z03 A;  4PV1 D;  2E76 D;  4NBE A;  1ULJ A;  2E4Q A;  1SJG A;  2CKF A;  4QDF A;  4NBE D;  2E4P A;  2NUM A;  4NBD A;  4PD4 E;  3GTS A;  5KLI C;  4H0L D;  5KKZ C;  2BCC E;  4NBD D;  1SQB E; 
#chains in the Genus database with same CATH topology
 2ZYL A;  1Q90 C;  1P84 E;  4NBC A;  4NBG A;  4AIV A;  1JM1 A;  2B24 A;  4NB8 D;  4EMJ B;  2YFL A;  2D2C D;  1O7N A;  3VMH D;  3H1I E;  2HMJ A;  1NTZ E;  2E74 D;  4QUR A;  3AZC A;  3CX5 E;  1BE3 E;  1O7P A;  3GTE A;  4H13 D;  2BMQ A;  3L74 E;  1O7M A;  4NB9 D;  4NBA A;  4HKV A;  2YIU C;  2HMK A;  3GCF A;  3L72 E;  1PP9 E;  2FYU E;  3L71 E;  3GCE A;  2NVE A;  2NVF A;  3GKE A;  4NBH A;  1EG9 A;  2NVG A;  2DE5 D;  1L0L E;  4NBB A;  4NBC D;  4NBH D;  4QDC A;  2YVJ B;  4HM3 A;  3GZX A;  4NBA D;  5KLV E;  4NB9 A;  4HM0 A;  1FQT A;  2E75 D;  3VCA A;  2XRX A;  2DE5 A;  1Z02 A;  3DQY A;  3H1L E;  1G8K B;  2HMO A;  1RFS A;  3VMI D;  2DE7 A;  3H1J E;  2NUK A;  4NBF D;  3VCP A;  1NYK A;  3C0D A;  1G8J B;  2JZA A;  1NTK E;  3CWB E;  1SQP E;  4HJL A;  2I7F A;  4NB8 A;  1EZV E;  2ZT9 D;  3GOB A;  4HM4 A;  3VMG A;  3GKQ A;  4OGQ D;  2IBZ E;  1KB9 E;  4HM5 A;  2HMN A;  1UUV A;  2B1X A;  1O7G A;  3TGU E;  3L70 E;  4QUQ A;  2QPZ A;  1VM9 A;  2BMR A;  2Q3W A;  4QDD A;  4NBG D;  1ZRT E;  1ULI A;  2XSO A;  3EQQ A;  3H1K E;  5BOK A;  1UUW A;  5CXM A;  1SQV E;  4H44 D;  4HM8 A;  3GZY A;  3L75 E;  1RIE A;  4P1B H;  2GBW A;  3BCC E;  5AEU A;  2YFJ A;  2HMM A;  2YFI A;  3D89 A;  3VMI A;  2XSH A;  2GBX A;  2QJP C;  4QDF B;  3L73 E;  2DE6 A;  4NBB D;  5HL4 A;  3GB4 A;  1NU1 E;  1NDO A;  1NTM E;  1O7W A;  3N0Q A;  1VF5 D;  1BCC E;  1VCK A;  2XR8 A;  3VMG D;  3FOU A;  1WQL A;  1SQQ E;  5AEW A;  2NWF A;  2QJY C;  4HM6 A;  2FYN C;  3VMH A;  1SQX E;  4NBF A;  3GL2 A;  3CXH E;  4P1C H;  2DE6 D;  4QCK A;  1PPJ E;  4HM2 A;  1L0N E;  2DE7 D;  2HML A;  2A06 E;  3EN1 A;  3GL0 A;  3H1H E;  2QJK C;  1Z01 A;  4AAY B;  2JO6 A;  4QUP A;  1KYO E;  4HM1 A;  2BMO A;  1O7H A;  4U3F E;  4HM7 A;  1WW9 A;  1Z03 A;  4PV1 D;  2E76 D;  4NBE A;  1ULJ A;  2E4Q A;  1SJG A;  2CKF A;  4QDF A;  4NBE D;  2E4P A;  2NUM A;  4NBD A;  4PD4 E;  3GTS A;  5KLI C;  4H0L D;  5KKZ C;  2BCC E;  4NBD D;  1SQB E; 
#chains in the Genus database with same CATH homology
 2ZYL A;  1Q90 C;  1P84 E;  4NBC A;  4NBG A;  4AIV A;  1JM1 A;  2B24 A;  4NB8 D;  4EMJ B;  2YFL A;  2D2C D;  1O7N A;  3VMH D;  3H1I E;  2HMJ A;  1NTZ E;  2E74 D;  4QUR A;  3AZC A;  3CX5 E;  1BE3 E;  1O7P A;  3GTE A;  4H13 D;  2BMQ A;  3L74 E;  1O7M A;  4NB9 D;  4NBA A;  4HKV A;  2YIU C;  2HMK A;  3GCF A;  3L72 E;  1PP9 E;  2FYU E;  3L71 E;  3GCE A;  2NVE A;  2NVF A;  3GKE A;  4NBH A;  1EG9 A;  2NVG A;  2DE5 D;  1L0L E;  4NBB A;  4NBC D;  4NBH D;  4QDC A;  2YVJ B;  4HM3 A;  3GZX A;  4NBA D;  5KLV E;  4NB9 A;  4HM0 A;  1FQT A;  2E75 D;  3VCA A;  2XRX A;  2DE5 A;  1Z02 A;  3DQY A;  3H1L E;  1G8K B;  2HMO A;  1RFS A;  3VMI D;  2DE7 A;  3H1J E;  2NUK A;  4NBF D;  3VCP A;  1NYK A;  3C0D A;  1G8J B;  2JZA A;  1NTK E;  3CWB E;  1SQP E;  4HJL A;  2I7F A;  4NB8 A;  1EZV E;  2ZT9 D;  3GOB A;  4HM4 A;  3VMG A;  3GKQ A;  4OGQ D;  2IBZ E;  1KB9 E;  4HM5 A;  2HMN A;  1UUV A;  2B1X A;  1O7G A;  3TGU E;  3L70 E;  4QUQ A;  2QPZ A;  1VM9 A;  2BMR A;  2Q3W A;  4QDD A;  4NBG D;  1ZRT E;  1ULI A;  2XSO A;  3EQQ A;  3H1K E;  5BOK A;  1UUW A;  5CXM A;  1SQV E;  4H44 D;  4HM8 A;  3GZY A;  3L75 E;  1RIE A;  4P1B H;  2GBW A;  3BCC E;  5AEU A;  2YFJ A;  2HMM A;  2YFI A;  3D89 A;  3VMI A;  2XSH A;  2GBX A;  2QJP C;  4QDF B;  3L73 E;  2DE6 A;  4NBB D;  5HL4 A;  3GB4 A;  1NU1 E;  1NDO A;  1NTM E;  1O7W A;  3N0Q A;  1VF5 D;  1BCC E;  1VCK A;  2XR8 A;  3VMG D;  3FOU A;  1WQL A;  1SQQ E;  5AEW A;  2NWF A;  2QJY C;  4HM6 A;  2FYN C;  3VMH A;  1SQX E;  4NBF A;  3GL2 A;  3CXH E;  4P1C H;  2DE6 D;  4QCK A;  1PPJ E;  4HM2 A;  1L0N E;  2DE7 D;  2HML A;  2A06 E;  3EN1 A;  3GL0 A;  3H1H E;  2QJK C;  1Z01 A;  4AAY B;  2JO6 A;  4QUP A;  1KYO E;  4HM1 A;  2BMO A;  1O7H A;  4U3F E;  4HM7 A;  1WW9 A;  1Z03 A;  4PV1 D;  2E76 D;  4NBE A;  1ULJ A;  2E4Q A;  1SJG A;  2CKF A;  4QDF A;  4NBE D;  2E4P A;  2NUM A;  4NBD A;  4PD4 E;  3GTS A;  5KLI C;  4H0L D;  5KKZ C;  2BCC E;  4NBD D;  1SQB E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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