2I30A

Human serum albumin complexed with myristate and salicylic acid
Total Genus 211
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
211
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Serum albumin
publication title Effect of human serum albumin on drug metabolism: Structural evidence of esterase activity of human serum albumin
pubmed doi rcsb
molecule tags Lipid binding protein
total genus 211
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2006-08-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2i30A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2i30A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2i30A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2i30A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2i30A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2i30A05
2BXKA 5GHKA 1KXPD 1J7EA 5IJFA 4IW1A 1H9ZA 4F5TA 5IIHA 4LB2A 5FUOA 1HK3A 2YDFA 1E7HA 2XSIA 2BXDA 2BXBA 2BXCA 4JK4A 3V09A 4N0UD 3V03A 5ID7A 2BXEA 1GNIA 4BKEA 3CX9A 1E78A 3B9LA 2VDBA 1E7GA 1E7FA 3JRYA 3TDLA 5IJEA 2I2ZA 3A73A 2BXFA 4HGMB 4OR0A 1HK5A 5IIUA 4J2VA 2BXGA 1KW2A 3LU6A 2I30A 1BM0A 5DBYA 3JQZA 2XVWA 5IFOA 4LB9A 2BXNA 1N5UA 4LA0A 4F5VA 5DQFA 2XVQA 1E7CA 4F5SA 4LUHA 5IJ5A 3LU7A 4Z69A 2BXOA 1HK4A 4G04A 4L8UA 4L9KA 4PO0A 1MA9A 5IIXA 3V08A 4HGKA 2BX8A 2VUFA 5HOZA 1HA2A 2XVVA 1HK1A 1BJ5A 1TF0A 2BXMA 1E7EA 2BXPA 4ZBQA 4LUFA 2VUEA 1GNJA 4E99A 3SQJA 4N0FD 2BXLA 4K71A 4S1YA 4EMXA 4G03A 2BXIA 5ID9A 1BKEA 1UORA 4F5UA 3LU8A 2XW1A 1LOTA 1AO6A 2BXAA 1J78A 4OT2A 4IW2A 4L9QA 1E7AA 1E7IA 1O9XA 4ZBRA 3UIVA 1HK2A 2XVUA 2XW0A 3B9MA 1E7BA 2BXQA 2BXHA 4K2CA
chains in the Genus database with same CATH superfamily
4C31B 2BXKA 5GHKA 1KXPD 1KDXA 2KWFA 1J7EA 5IJFA 4IW1A 1H9ZA 4FJCB 4F5TA 5IIHA 1LNSA 4LB2A 5FUOA 4OTUA 2LXTA 3FWBC 5D7GA 1HK3A 4D7XA 2QM6A 3NVIA 3ICXA 4ZUXV 2YDFA 1E7HA 2LXSA 2BXDA 2XSIA 5GINA 3MHHB 4DM0A 2BXBA 2BXCA 4JK4A 3V09A 4N0UD 3V03A 5B5TA 5ID7A 2Z8IA 2BXEA 1GNIA 4BKEA 1MUSA 2OT3A 2K0NA 3KJLA 3CX9A 1E78A 3B9LA 3W1SA 1MIVA 2VDBA 2ROHA 1E7GA 4N3ZA 1E7FA 1TXUA 3JRYA 2EFDA 3TDLA 2DBWA 2E0YA 2Z8JA 5IJEA 2I2ZA 5GIPA 3A73A 2BXFA 2DBUA 1IJGA 4HGMB 4OR0A 2EFHA 2XMOA 2E0XA 1HK5A 5IIUA 4W4UB 3VQIA 2EFCA 4J2VA 2BXGA 2LOQA 1KW2A 3LU6A 3KIKA 2I30A 3NVMA 1BM0A 4G01A 3GQUA 3JQZA 4OTTA 2XVWA 5DBYA 5IFOA 4LB9A 2BXNA 1N5UA 3M99C 4I9OA 4LA0A 3WHQA 4F5VA 5DQFA 2XVQA 1SB0A 3NVKA 4MBEC 1E7CA 2QHBA 4F5SA 3G9KD 1FOUA 3SIVB 4LUHA 2AJEA 5IJ5A 3LU7A 4Z69A 2BXOA 3ECPA 1HK4A 4G04A 4L8UA 4L9KA 4PO0A 1MA9A 5IIXA 1NT2B 3H37A 1MM8A 3V08A 4ZCGA 4HGKA 4K2CA 2BX8A 2VUFA 5HOZA 2KBZA 1VFIA 1HA2A 1MIWA 2XVVA 1HK1A 3H3AA 1BJ5A 4FK5B 3WHSA 1TF0A 1H5WA 2BXMA 1E7EA 2BXPA 4GG2A 4ZBQA 4LUFA 2OZBB 2EFEA 2VUEA 1GNJA 4E99A 3SQJA 4GDLB 3BPJA 4N0FD 2JUHA 2QMCA 2BXLA 2NNWA 2DYOA 3GA9L 3MHSB 4K71A 4WA6B 2DG5A 4S1YA 2DBXA 2LQHA 4EMXA 4G03A 2DYMA 4GDKB 2LQIA 2BXIA 5ID9A 4FIPB 3PLAA 1BKEA 4M70B 2AGHB 1UORA 2CKXA 4F5UA 3LU8A 2XW1A 3SIUB 1LOTA 2V36A 4Z9OA 3NMUA 3FNMA 1AO6A 2BXAA 1J78A 4OT2A 5BPKA 4IW2A 4L9QA 4ZBKA 4BY9C 1E7AA 1E7IA 1O9XA 4GDXA 2Z8KA 4ZBRA 3FWCC 4NAWB 3UIVA 1MIYA 1HK2A 4ZC6A 2XVUA 4DHXB 1VZSA 3GQXA 2XW0A 3B9MA 1E7BA 2GUTA 5GIOA 2BXQA 2BXHA 3WHRA 3A75A 4TQ0A 1MUHA 2NQOA 1JNBA 4TQ1A
chains in the Genus database with same CATH topology
4C31B 2BXKA 5GHKA 1KXPD 1J7EA 5IJFA 4IW1A 1H9ZA 4FJCB 4F5TA 5IIHA 1LNSA 4LB2A 5FUOA 4OTUA 3FWBC 5D7GA 1HK3A 2QM6A 3NVIA 3ICXA 4ZUXV 2YDFA 1E7HA 2XSIA 2BXDA 5GINA 3MHHB 2BXBA 2BXCA 4JK4A 3V09A 4N0UD 3V03A 5B5TA 5ID7A 2Z8IA 2BXEA 1GNIA 4BKEA 2OT3A 3KJLA 3CX9A 1E78A 3B9LA 3W1SA 1MIVA 2VDBA 2ROHA 1E7GA 4N3ZA 1E7FA 1TXUA 3JRYA 2EFDA 3TDLA 2DBWA 2E0YA 2Z8JA 5IJEA 2I2ZA 5GIPA 3A73A 2BXFA 2DBUA 1IJGA 4HGMB 4OR0A 2EFHA 2XMOA 2E0XA 1HK5A 5IIUA 4W4UB 3VQIA 2EFCA 4J2VA 2BXGA 2LOQA 1KW2A 3LU6A 3KIKA 2I30A 3NVMA 1BM0A 4G01A 3GQUA 3JQZA 4OTTA 2XVWA 5DBYA 5IFOA 4LB9A 2BXNA 1N5UA 3M99C 4LA0A 3WHQA 4F5VA 3NVKA 5DQFA 2XVQA 4MBEC 1E7CA 2QHBA 4F5SA 3G9KD 1FOUA 3SIVB 4LUHA 2AJEA 5IJ5A 3LU7A 4Z69A 2BXOA 1HK4A 4G04A 4L8UA 4L9KA 4PO0A 1MA9A 5IIXA 1NT2B 3H37A 3V08A 4ZCGA 4HGKA 4K2CA 2BX8A 2VUFA 5HOZA 2KBZA 1VFIA 1HA2A 1MIWA 2XVVA 1HK1A 3H3AA 1BJ5A 4FK5B 3WHSA 1TF0A 1H5WA 2BXMA 1E7EA 2BXPA 4GG2A 4ZBQA 4LUFA 2OZBB 2EFEA 2VUEA 1GNJA 4E99A 3SQJA 4GDLB 4N0FD 2JUHA 2QMCA 2BXLA 2NNWA 2DYOA 3GA9L 3MHSB 4K71A 4WA6B 2DG5A 4S1YA 2DBXA 4EMXA 4G03A 2DYMA 4GDKB 2BXIA 5ID9A 4FIPB 3PLAA 1BKEA 4M70B 1UORA 2CKXA 4F5UA 3LU8A 2XW1A 3SIUB 1LOTA 2V36A 4Z9OA 3NMUA 3FNMA 1AO6A 2BXAA 1J78A 4OT2A 5BPKA 4IW2A 4L9QA 4ZBKA 4BY9C 1E7AA 1E7IA 1O9XA 4GDXA 2Z8KA 4ZBRA 3FWCC 4NAWB 3UIVA 1MIYA 1HK2A 4ZC6A 2XVUA 4DHXB 1VZSA 3GQXA 2XW0A 3B9MA 1E7BA 5GIOA 2BXQA 2BXHA 3WHRA 3A75A 4TQ0A 2NQOA 1JNBA 4TQ1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXK A;  5GHK A;  1KXP D;  1J7E A;  5IJF A;  4IW1 A;  1H9Z A;  4F5T A;  5IIH A;  4LB2 A;  5FUO A;  1HK3 A;  2YDF A;  1E7H A;  2XSI A;  2BXD A;  2BXB A;  2BXC A;  4JK4 A;  3V09 A;  4N0U D;  3V03 A;  5ID7 A;  2BXE A;  1GNI A;  4BKE A;  3CX9 A;  1E78 A;  3B9L A;  2VDB A;  1E7G A;  1E7F A;  3JRY A;  3TDL A;  5IJE A;  2I2Z A;  3A73 A;  2BXF A;  4HGM B;  4OR0 A;  1HK5 A;  5IIU A;  4J2V A;  2BXG A;  1KW2 A;  3LU6 A;  2I30 A;  1BM0 A;  5DBY A;  3JQZ A;  2XVW A;  5IFO A;  4LB9 A;  2BXN A;  1N5U A;  4LA0 A;  4F5V A;  5DQF A;  2XVQ A;  1E7C A;  4F5S A;  4LUH A;  5IJ5 A;  3LU7 A;  4Z69 A;  2BXO A;  1HK4 A;  4G04 A;  4L8U A;  4L9K A;  4PO0 A;  1MA9 A;  5IIX A;  3V08 A;  4HGK A;  2BX8 A;  2VUF A;  5HOZ A;  1HA2 A;  2XVV A;  1HK1 A;  1BJ5 A;  1TF0 A;  2BXM A;  1E7E A;  2BXP A;  4ZBQ A;  4LUF A;  2VUE A;  1GNJ A;  4E99 A;  3SQJ A;  4N0F D;  2BXL A;  4K71 A;  4S1Y A;  4EMX A;  4G03 A;  2BXI A;  5ID9 A;  1BKE A;  1UOR A;  4F5U A;  3LU8 A;  2XW1 A;  1LOT A;  1AO6 A;  2BXA A;  1J78 A;  4OT2 A;  4IW2 A;  4L9Q A;  1E7A A;  1E7I A;  1O9X A;  4ZBR A;  3UIV A;  1HK2 A;  2XVU A;  2XW0 A;  3B9M A;  1E7B A;  2BXQ A;  2BXH A;  4K2C A; 
#chains in the Genus database with same CATH topology
 4C31 B;  2BXK A;  5GHK A;  1KXP D;  1KDX A;  2KWF A;  1J7E A;  5IJF A;  4IW1 A;  1H9Z A;  4FJC B;  4F5T A;  5IIH A;  1LNS A;  4LB2 A;  5FUO A;  4OTU A;  2LXT A;  3FWB C;  5D7G A;  1HK3 A;  4D7X A;  2QM6 A;  3NVI A;  3ICX A;  4ZUX V;  2YDF A;  1E7H A;  2LXS A;  2BXD A;  2XSI A;  5GIN A;  3MHH B;  4DM0 A;  2BXB A;  2BXC A;  4JK4 A;  3V09 A;  4N0U D;  3V03 A;  5B5T A;  5ID7 A;  2Z8I A;  2BXE A;  1GNI A;  4BKE A;  1MUS A;  2OT3 A;  2K0N A;  3KJL A;  3CX9 A;  1E78 A;  3B9L A;  3W1S A;  1MIV A;  2VDB A;  2ROH A;  1E7G A;  4N3Z A;  1E7F A;  1TXU A;  3JRY A;  2EFD A;  3TDL A;  2DBW A;  2E0Y A;  2Z8J A;  5IJE A;  2I2Z A;  5GIP A;  3A73 A;  2BXF A;  2DBU A;  1IJG A;  4HGM B;  4OR0 A;  2EFH A;  2XMO A;  2E0X A;  1HK5 A;  5IIU A;  4W4U B;  3VQI A;  2EFC A;  4J2V A;  2BXG A;  2LOQ A;  1KW2 A;  3LU6 A;  3KIK A;  2I30 A;  3NVM A;  1BM0 A;  4G01 A;  3GQU A;  3JQZ A;  4OTT A;  2XVW A;  5DBY A;  5IFO A;  4LB9 A;  2BXN A;  1N5U A;  3M99 C;  4I9O A;  4LA0 A;  3WHQ A;  4F5V A;  5DQF A;  2XVQ A;  1SB0 A;  3NVK A;  4MBE C;  1E7C A;  2QHB A;  4F5S A;  3G9K D;  1FOU A;  3SIV B;  4LUH A;  2AJE A;  5IJ5 A;  3LU7 A;  4Z69 A;  2BXO A;  3ECP A;  1HK4 A;  4G04 A;  4L8U A;  4L9K A;  4PO0 A;  1MA9 A;  5IIX A;  1NT2 B;  3H37 A;  1MM8 A;  3V08 A;  4ZCG A;  4HGK A;  4K2C A;  2BX8 A;  2VUF A;  5HOZ A;  2KBZ A;  1VFI A;  1HA2 A;  1MIW A;  2XVV A;  1HK1 A;  3H3A A;  1BJ5 A;  4FK5 B;  3WHS A;  1TF0 A;  1H5W A;  2BXM A;  1E7E A;  2BXP A;  4GG2 A;  4ZBQ A;  4LUF A;  2OZB B;  2EFE A;  2VUE A;  1GNJ A;  4E99 A;  3SQJ A;  4GDL B;  3BPJ A;  4N0F D;  2JUH A;  2QMC A;  2BXL A;  2NNW A;  2DYO A;  3GA9 L;  3MHS B;  4K71 A;  4WA6 B;  2DG5 A;  4S1Y A;  2DBX A;  2LQH A;  4EMX A;  4G03 A;  2DYM A;  4GDK B;  2LQI A;  2BXI A;  5ID9 A;  4FIP B;  3PLA A;  1BKE A;  4M70 B;  2AGH B;  1UOR A;  2CKX A;  4F5U A;  3LU8 A;  2XW1 A;  3SIU B;  1LOT A;  2V36 A;  4Z9O A;  3NMU A;  3FNM A;  1AO6 A;  2BXA A;  1J78 A;  4OT2 A;  5BPK A;  4IW2 A;  4L9Q A;  4ZBK A;  4BY9 C;  1E7A A;  1E7I A;  1O9X A;  4GDX A;  2Z8K A;  4ZBR A;  3FWC C;  4NAW B;  3UIV A;  1MIY A;  1HK2 A;  4ZC6 A;  2XVU A;  4DHX B;  1VZS A;  3GQX A;  2XW0 A;  3B9M A;  1E7B A;  2GUT A;  5GIO A;  2BXQ A;  2BXH A;  3WHR A;  3A75 A;  4TQ0 A;  1MUH A;  2NQO A;  1JNB A;  4TQ1 A; 
#chains in the Genus database with same CATH homology
 4C31 B;  2BXK A;  5GHK A;  1KXP D;  1J7E A;  5IJF A;  4IW1 A;  1H9Z A;  4FJC B;  4F5T A;  5IIH A;  1LNS A;  4LB2 A;  5FUO A;  4OTU A;  3FWB C;  5D7G A;  1HK3 A;  2QM6 A;  3NVI A;  3ICX A;  4ZUX V;  2YDF A;  1E7H A;  2XSI A;  2BXD A;  5GIN A;  3MHH B;  2BXB A;  2BXC A;  4JK4 A;  3V09 A;  4N0U D;  3V03 A;  5B5T A;  5ID7 A;  2Z8I A;  2BXE A;  1GNI A;  4BKE A;  2OT3 A;  3KJL A;  3CX9 A;  1E78 A;  3B9L A;  3W1S A;  1MIV A;  2VDB A;  2ROH A;  1E7G A;  4N3Z A;  1E7F A;  1TXU A;  3JRY A;  2EFD A;  3TDL A;  2DBW A;  2E0Y A;  2Z8J A;  5IJE A;  2I2Z A;  5GIP A;  3A73 A;  2BXF A;  2DBU A;  1IJG A;  4HGM B;  4OR0 A;  2EFH A;  2XMO A;  2E0X A;  1HK5 A;  5IIU A;  4W4U B;  3VQI A;  2EFC A;  4J2V A;  2BXG A;  2LOQ A;  1KW2 A;  3LU6 A;  3KIK A;  2I30 A;  3NVM A;  1BM0 A;  4G01 A;  3GQU A;  3JQZ A;  4OTT A;  2XVW A;  5DBY A;  5IFO A;  4LB9 A;  2BXN A;  1N5U A;  3M99 C;  4LA0 A;  3WHQ A;  4F5V A;  3NVK A;  5DQF A;  2XVQ A;  4MBE C;  1E7C A;  2QHB A;  4F5S A;  3G9K D;  1FOU A;  3SIV B;  4LUH A;  2AJE A;  5IJ5 A;  3LU7 A;  4Z69 A;  2BXO A;  1HK4 A;  4G04 A;  4L8U A;  4L9K A;  4PO0 A;  1MA9 A;  5IIX A;  1NT2 B;  3H37 A;  3V08 A;  4ZCG A;  4HGK A;  4K2C A;  2BX8 A;  2VUF A;  5HOZ A;  2KBZ A;  1VFI A;  1HA2 A;  1MIW A;  2XVV A;  1HK1 A;  3H3A A;  1BJ5 A;  4FK5 B;  3WHS A;  1TF0 A;  1H5W A;  2BXM A;  1E7E A;  2BXP A;  4GG2 A;  4ZBQ A;  4LUF A;  2OZB B;  2EFE A;  2VUE A;  1GNJ A;  4E99 A;  3SQJ A;  4GDL B;  4N0F D;  2JUH A;  2QMC A;  2BXL A;  2NNW A;  2DYO A;  3GA9 L;  3MHS B;  4K71 A;  4WA6 B;  2DG5 A;  4S1Y A;  2DBX A;  4EMX A;  4G03 A;  2DYM A;  4GDK B;  2BXI A;  5ID9 A;  4FIP B;  3PLA A;  1BKE A;  4M70 B;  1UOR A;  2CKX A;  4F5U A;  3LU8 A;  2XW1 A;  3SIU B;  1LOT A;  2V36 A;  4Z9O A;  3NMU A;  3FNM A;  1AO6 A;  2BXA A;  1J78 A;  4OT2 A;  5BPK A;  4IW2 A;  4L9Q A;  4ZBK A;  4BY9 C;  1E7A A;  1E7I A;  1O9X A;  4GDX A;  2Z8K A;  4ZBR A;  3FWC C;  4NAW B;  3UIV A;  1MIY A;  1HK2 A;  4ZC6 A;  2XVU A;  4DHX B;  1VZS A;  3GQX A;  2XW0 A;  3B9M A;  1E7B A;  5GIO A;  2BXQ A;  2BXH A;  3WHR A;  3A75 A;  4TQ0 A;  2NQO A;  1JNB A;  4TQ1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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