2I47A

Crystal structure of catalytic domain of tace with inhibitor
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
255
structure length
255
Chain Sequence
PMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of potent and selective TACE inhibitors via the S1 pocket.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords ADAM 17
total genus 84
structure length 255
sequence length 255
chains with identical sequence B, C, D
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2006-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2i47A00
1I1IP 1D8FA 1KUHA 4PKSA 2FV9A 3V96B 1KUGA 2D1OA 3K7NA 4JIJA 1MNCA 1Y8JA 1KAPP 1D5JA 4GWNA 1K7QA 2AYKA 4DPEA 1KBCA 4FXYP 1FBLA 1HOVA 3TS4A 1C8TA 3KMCA 3F16A 2DW0A 1CGFA 3KECA 5CUHA 2WO8A 4A7BA 1DTHA 1IAGA 3B2ZA 2J0TA 3Q2GA 1JK3A 1BZSA 1K7IA 1XFZA 3LUNA 1ND1A 2JSDA 4EFSA 3B8ZA 1BQQM 1JH1A 1ZVXA 1XFXA 1G49A 2WOAA 3F18A 1WNIA 1SLNA 4CTHA 2EROA 4GQLA 3LK8A 2OZRA 2MZEA 3G42A 1SMPA 1MMBA 2OXZA 4HX3A 3KWVC 1OM6A 2W15A 2E3XA 3LE9A 1QJIA 4DF9A 1R1IA 5L7FA 1IAEA 2W14A 1IABA 3ZUKA 3ZVSA 1Q3AA 4XM7A 3HDAP 2X7MA 2RJQA 1ZS0A 1RM8A 4H49A 4J4MA 1DMTA 3WV3A 1XURA 4GR0A 2O3EA 1R55A 4L6TA 1PWQA 1PWUA 1C3IA 5I4OA 4GF1A 4I35A 4H1QA 1GKDA 2JT5A 1YQYA 3O64A 1GE6A 2OY4A 1OM8A 1SU3A 2Y6CA 2OW2A 5D1UA 1CXVA 3KHIA 1HTDA 3OHLA 2USNA 2MLSA 1FLSA 3EDZA 1ZTQA 3LQBA 3E8RA 1JKYA 1KUKA 1UMSA 3LGPA 1ATLA 1ZP5A 3HBVP 2CKIA 2K2GA 1GE7A 4PKVA 3TVCA 4H30A 1BQOA 1USNA 3DL1A 966CA 3BA0A 3F19A 2DW1A 3LKAA 1B3DA 1BKCI 1G4KA 5I2ZA 1MMPA 2N8RA 3EWJA 4ILWD 2JT6A 1GE5A 2PJTA 4XBHA 1RMZA 3KMEA 2OI0A 1FM1A 1GKCA 1Y0VA 1BUVM 1KUIA 1OM7A 4ON1A 3HYGA 1BM6A 4H2EA 4JPAA 1XFUA 2X3CA 3ZXHA 1J7NA 1BKCE 3O2XA 3TSKA 5D1SA 4GUYA 2Y6DA 1A86A 1R1JA 4AIGA 3DNGA 1OMJA 3LEAA 1KUFA 1XUCA 1JAOA 3HY9A 1EB6A 1QUAA 2OW1A 2JIHA 3EHYA 3L0TA 1SATA 3RTTA 3DWBA 3LIKA 5L79A 4PKQA 4G9LA 3ELMA 1JAPA 2DDYA 3P1VA 5D3CA 1K7GA 1XFVA 3P24A 3AIGA 5D7WA 1I73A 3DPFA 3NX7A 4XM6A 1L6JA 1D8MA 2OXWA 1HY7A 5JMYA 1JANA 4GR3A 1GO7P 2X3BA 3AYUA 4FU4A 3HB2P 2WO9A 1BSWA 4AXQA 4AUOA 4PKWA 3F1AA 4L63A 5BOYA 3LJGA 1Z3JA 4QKZA 5CZMA 1BUDA 2OVZA 3WV1A 1JJ9A 4L19A 1EUBA 3DPEA 3I7GA 4ZR5A 3LMCA 3L0VA 2I47A 3EDHA 3I7IA 4H76A 2K9CA 1SLMA 1JIZA 2ERPA 1SRPA 1JAQA 4JP4A 1CGEA 1JIWP 3HBUP 2E2DA 2XS3A 4WF6A 2MZHA 2HU6A 3F15A 3GBOA 4WK7A 1MMQA 5BOTA 1ZXCA 2QPJA 5I3MA 1HFCA 1I76A 3DSLA 5D1TA 4A3WA 3VTGA 4AYKA 1A85A 2OW9A 2W0DA 1EAKA 4Q1LA 1CIZA 3HY7A 2XS4A 1O0TA 3KEJA 2JNPA 4FVLA 5I12A 1XFYA 3K7LA 1CK7A 1AKLA 1G9KA 2D1NA 1ZXVA 4WKEA 1IADA 3EDIA 2Z2DA 1AF0A 1CGLA 4PKUA 4PKRA 1UEAA 1UTTA 1O0QA 1G12A 5H8XA 2OXUA 2W12A 1OO9A 4IUWA 3N2VA 1HFSA 4G0DA 4WZVA 1XFWA 3B92A 1R54A 2W13A 1R1HA 4DD8A 1B8YA 1QIBA 1GO8P 2O36A 2YB9A 3SHIA 3VI1A 4XM8A 1BIWA 1OS2A 5I0LA 1OS9A 4JQGA 1ASTA 1PWWA 1UTZA 2TCLA 3N2UA 1YCMA 2OY2A 5B5OA 1QJJA 2KRJA 830CA 2DW2A 2DDFA 4H3XA 3CKIA 3EDGA 2POJA 2OVXA 1CAQA 4XCTA 5B5PA 5CXAA 456CA 2AIGP 1YOUA 3USNA 4I03A 1HV5A 4H82A 4PKTA 1UMTA 3EHXA 1QIAA 1IACA 5D2BA 1MMRA 2ERQA 1BKCA 1Y93A 2MZIA 2CLTA 1PWVA 5BPAA 1S4BP 4IN9A 3RTSA 3Q2HA 3UVCA 1H71P 4JA1A 2SRTA 2MLRA 5LABA 2A8HA 1XUDA 3TT4A 3AYKA 3U1RA 2OW0A 1IAAA 4H84A 4HMAA 1G05A 2L0RA 1AYKA 1D7XA 4WKIA 4FXQA 1CQRA 2V4BA 1QICA 3LJZA 2YIGA 1PWPA 3G5CA 3MA2A 3LUMA 2X3AA 3LIRA 3KRYA 4IJOA 3HDBA 4GR8A 4DV8A 1ROSA 2FV5A 3OHOA 3LJTA 2J83A 3LILA 4R3VA 3LQ0A 2RJPA 3F17A 3WV2A 1YP1A 1GXDA 3KEKA 4GWMA 5I43A 1C7KA
chains in the Genus database with same CATH superfamily
3DTKA 1I1IP 1D8FA 1KUHA 4PKSA 2FV9A 3V96B 3DTIA 1KUGA 2D1OA 3K7NA 4JIJA 1MNCA 1Y8JA 1KAPP 1D5JA 4GWNA 1K7QA 2AYKA 4DPEA 1KBCA 4FXYP 1FBLA 1HOVA 3TS4A 1C8TA 3KMCA 3F16A 2DW0A 1CGFA 3KECA 5CUHA 2WO8A 4A7BA 1DTHA 1IAGA 3B2ZA 2J0TA 3Q2GA 1JK3A 1BZSA 1K7IA 1XFZA 3LUNA 1ND1A 2JSDA 4EFSA 3B8ZA 1BQQM 1JH1A 1ZVXA 1XFXA 1G49A 2WOAA 3F18A 1WNIA 1SLNA 4CTHA 2EROA 4GQLA 3LK8A 2OZRA 2MZEA 3G42A 1SMPA 1MMBA 2OXZA 4HX3A 3KWVC 1OM6A 2W15A 2E3XA 3LE9A 1QJIA 4DF9A 1R1IA 5L7FA 1IAEA 2W14A 1IABA 3ZUKA 3ZVSA 1Q3AA 4XM7A 1XAXA 3HDAP 2X7MA 2RJQA 1ZS0A 1RM8A 4H49A 4J4MA 1DMTA 3WV3A 1XURA 4GR0A 2O3EA 1R55A 4L6TA 1PWQA 1PWUA 1C3IA 5I4OA 4GF1A 4I35A 4H1QA 1GKDA 2JT5A 1YQYA 3O64A 1GE6A 2OY4A 1OM8A 1SU3A 2Y6CA 2OW2A 5D1UA 1CXVA 3KHIA 1HTDA 3OHLA 2USNA 2MLSA 1FLSA 3EDZA 1ZTQA 3LQBA 3E8RA 1JKYA 1KUKA 1UMSA 3LGPA 1ATLA 1ZP5A 3HBVP 2CKIA 2K2GA 1GE7A 4PKVA 3TVCA 4H30A 1BQOA 1USNA 3DL1A 966CA 3BA0A 3F19A 2DW1A 3LKAA 1B3DA 1BKCI 1G4KA 5I2ZA 1MMPA 2N8RA 3EWJA 4ILWD 2JT6A 1GE5A 2PJTA 4XBHA 1RMZA 3KMEA 2OI0A 1FM1A 1GKCA 1Y0VA 1BUVM 1KUIA 1OM7A 4ON1A 3HYGA 1BM6A 4H2EA 4JPAA 1XFUA 2X3CA 3ZXHA 1J7NA 1BKCE 3O2XA 3TSKA 5D1SA 4GUYA 2Y6DA 1A86A 1R1JA 4AIGA 3DNGA 3DTEA 1OMJA 3LEAA 1KUFA 1XUCA 1JAOA 3HY9A 1EB6A 1QUAA 2OW1A 2JIHA 3EHYA 3L0TA 1SATA 3RTTA 3DWBA 3LIKA 5L79A 4PKQA 4G9LA 3ELMA 1JAPA 2DDYA 3P1VA 5D3CA 1K7GA 1XFVA 3P24A 3AIGA 5D7WA 1I73A 3DPFA 3NX7A 4XM6A 1L6JA 1D8MA 2OXWA 1HY7A 4L7AA 1JANA 5JMYA 4GR3A 1GO7P 2X3BA 3AYUA 4FU4A 3HB2P 2WO9A 1BSWA 4AXQA 4AUOA 4PKWA 3F1AA 4L63A 5BOYA 3LJGA 1Z3JA 4QKZA 5CZMA 1BUDA 2OVZA 3WV1A 1JJ9A 4L19A 1EUBA 3DPEA 3I7GA 4ZR5A 3LMCA 3L0VA 2I47A 3EDHA 3I7IA 4H76A 2K9CA 1SLMA 1JIZA 2ERPA 1SRPA 1JAQA 4JP4A 1CGEA 1JIWP 3HBUP 2E2DA 2XS3A 4WF6A 2MZHA 2HU6A 3F15A 3GBOA 4WK7A 1MMQA 5BOTA 1ZXCA 2QPJA 5I3MA 1HFCA 1I76A 3DSLA 5D1TA 1OZ9A 4A3WA 3VTGA 4AYKA 1A85A 2OW9A 2W0DA 1EAKA 4Q1LA 1CIZA 3HY7A 2YUFA 2XS4A 1O0TA 3KEJA 2JNPA 4FVLA 5I12A 1XFYA 3K7LA 1CK7A 1AKLA 1G9KA 2D1NA 1ZXVA 4WKEA 1IADA 3EDIA 2Z2DA 1AF0A 1CGLA 4PKUA 4PKRA 1UEAA 1UTTA 1O0QA 1G12A 5H8XA 2OXUA 2W12A 1OO9A 4IUWA 3N2VA 1HFSA 4G0DA 4WZVA 1XFWA 3B92A 1R54A 2W13A 1R1HA 4DD8A 1B8YA 1QIBA 1GO8P 2O36A 2YB9A 3SHIA 3VI1A 4XM8A 1BIWA 1OS2A 5I0LA 1OS9A 4JQGA 1ASTA 1PWWA 1UTZA 2TCLA 3N2UA 1YCMA 2OY2A 5B5OA 1QJJA 2KRJA 830CA 2DW2A 2DDFA 4H3XA 3CKIA 3EDGA 2POJA 2OVXA 1CAQA 4XCTA 5B5PA 5CXAA 456CA 2AIGP 1YOUA 3USNA 4I03A 1HV5A 4H82A 4PKTA 1UMTA 3EHXA 1QIAA 1IACA 5D2BA 1MMRA 2ERQA 1BKCA 1Y93A 2MZIA 2CLTA 1PWVA 5BPAA 1S4BP 4IN9A 3RTSA 3Q2HA 3UVCA 1H71P 4JA1A 2SRTA 2MLRA 5LABA 2A8HA 1XUDA 3TT4A 3AYKA 3U1RA 2OW0A 1IAAA 4H84A 4HMAA 1G05A 2L0RA 1AYKA 1D7XA 4WKIA 4FXQA 1XM5A 1CQRA 2V4BA 1QICA 3LJZA 2YIGA 1PWPA 3G5CA 3MA2A 3LUMA 2X3AA 1TVIA 3LIRA 3KRYA 4IJOA 3HDBA 4GR8A 4DV8A 1ROSA 2FV5A 3OHOA 3LJTA 2J83A 3LILA 4R3VA 3LQ0A 2RJPA 3F17A 3WV2A 1YP1A 1GXDA 3KEKA 4GWMA 5I43A 1C7KA
chains in the Genus database with same CATH topology
3DTKA 1I1IP 1D8FA 1KUHA 4PKSA 2FV9A 3V96B 3DTIA 1KUGA 2D1OA 3K7NA 4JIJA 1MNCA 1Y8JA 1KAPP 1D5JA 4GWNA 1K7QA 2AYKA 4DPEA 1KBCA 4FXYP 1FBLA 1HOVA 3TS4A 1C8TA 3KMCA 3F16A 2DW0A 1CGFA 3KECA 5CUHA 2WO8A 4A7BA 1DTHA 1IAGA 3B2ZA 2J0TA 3Q2GA 1JK3A 1BZSA 1K7IA 1XFZA 3LUNA 1ND1A 2JSDA 4EFSA 3B8ZA 1BQQM 1JH1A 1ZVXA 1XFXA 1G49A 2WOAA 3F18A 1WNIA 1SLNA 4CTHA 2EROA 4GQLA 3LK8A 2OZRA 2MZEA 3G42A 1SMPA 1MMBA 2OXZA 4HX3A 3KWVC 1OM6A 2W15A 2E3XA 3LE9A 1QJIA 4DF9A 1R1IA 5L7FA 1IAEA 2W14A 1IABA 3ZUKA 3ZVSA 1Q3AA 4XM7A 3HDAP 2X7MA 2RJQA 1ZS0A 1RM8A 4H49A 4J4MA 1DMTA 3WV3A 1XURA 4GR0A 2O3EA 1R55A 4L6TA 1PWQA 1PWUA 1C3IA 5I4OA 4GF1A 4I35A 4H1QA 1GKDA 2JT5A 1YQYA 3O64A 1GE6A 2OY4A 1OM8A 1SU3A 2Y6CA 2OW2A 5D1UA 1CXVA 3KHIA 1HTDA 3OHLA 2USNA 2MLSA 1FLSA 3EDZA 1ZTQA 3LQBA 3E8RA 1JKYA 1KUKA 1UMSA 3LGPA 1ATLA 1ZP5A 3HBVP 2CKIA 2K2GA 1GE7A 4PKVA 3TVCA 4H30A 1BQOA 1USNA 3DL1A 966CA 3BA0A 3F19A 2DW1A 3LKAA 1B3DA 1BKCI 1G4KA 5I2ZA 1MMPA 2N8RA 3EWJA 4ILWD 2JT6A 1GE5A 2PJTA 4XBHA 1RMZA 3KMEA 2OI0A 1FM1A 1GKCA 1Y0VA 1BUVM 1KUIA 1OM7A 4ON1A 3HYGA 1BM6A 4H2EA 4JPAA 1XFUA 2X3CA 3ZXHA 1J7NA 1BKCE 3O2XA 3TSKA 5D1SA 4GUYA 2Y6DA 1A86A 1R1JA 4AIGA 3DNGA 3DTEA 1OMJA 3LEAA 1KUFA 1XUCA 1JAOA 3HY9A 1EB6A 1QUAA 2OW1A 2JIHA 3EHYA 3L0TA 1SATA 3RTTA 3DWBA 3LIKA 5L79A 4PKQA 4G9LA 3ELMA 1JAPA 2DDYA 3P1VA 5D3CA 1K7GA 1XFVA 3P24A 3AIGA 5D7WA 1I73A 3DPFA 3NX7A 4XM6A 1L6JA 1D8MA 2OXWA 1HY7A 4L7AA 1JANA 5JMYA 4GR3A 1GO7P 2X3BA 3AYUA 4FU4A 3HB2P 2WO9A 1BSWA 4AXQA 4AUOA 4PKWA 3F1AA 4L63A 5BOYA 3LJGA 1Z3JA 4QKZA 5CZMA 1BUDA 2OVZA 3WV1A 1JJ9A 4L19A 1EUBA 3DPEA 3I7GA 4ZR5A 3LMCA 3L0VA 2I47A 3EDHA 3I7IA 4H76A 2K9CA 1SLMA 1JIZA 2ERPA 1SRPA 1JAQA 4JP4A 1CGEA 1JIWP 3HBUP 2E2DA 2XS3A 4WF6A 2MZHA 2HU6A 3F15A 3GBOA 4WK7A 1MMQA 5BOTA 1ZXCA 2QPJA 5I3MA 1HFCA 1I76A 3DSLA 5D1TA 4A3WA 3VTGA 4AYKA 1A85A 2OW9A 2W0DA 1EAKA 4Q1LA 1CIZA 3HY7A 2YUFA 2XS4A 1O0TA 3KEJA 2JNPA 4FVLA 5I12A 1XFYA 3K7LA 1CK7A 1AKLA 1G9KA 2D1NA 1ZXVA 4WKEA 1IADA 3EDIA 2Z2DA 1AF0A 1CGLA 4PKUA 4PKRA 1UEAA 1UTTA 1O0QA 1G12A 5H8XA 2OXUA 2W12A 1OO9A 4IUWA 3N2VA 1HFSA 4G0DA 4WZVA 1XFWA 3B92A 1R54A 2W13A 1R1HA 4DD8A 1B8YA 1QIBA 1GO8P 2O36A 2YB9A 3SHIA 3VI1A 4XM8A 1BIWA 1OS2A 5I0LA 1OS9A 4JQGA 1ASTA 1PWWA 1UTZA 2TCLA 3N2UA 1YCMA 2OY2A 5B5OA 1QJJA 2KRJA 830CA 2DW2A 2DDFA 4H3XA 3CKIA 3EDGA 2POJA 2OVXA 1CAQA 4XCTA 5B5PA 5CXAA 456CA 2AIGP 1YOUA 3USNA 4I03A 1HV5A 4H82A 4PKTA 1UMTA 3EHXA 1QIAA 1IACA 5D2BA 1MMRA 2ERQA 1BKCA 1Y93A 2MZIA 2CLTA 1PWVA 5BPAA 1S4BP 4IN9A 3RTSA 3Q2HA 3UVCA 1H71P 4JA1A 2SRTA 2MLRA 5LABA 2A8HA 1XUDA 3TT4A 3AYKA 3U1RA 2OW0A 1IAAA 4H84A 4HMAA 1G05A 2L0RA 1AYKA 1D7XA 4WKIA 4FXQA 1CQRA 2V4BA 1QICA 3LJZA 2YIGA 1PWPA 3G5CA 3MA2A 3LUMA 2X3AA 3LIRA 3KRYA 4IJOA 3HDBA 4GR8A 4DV8A 1ROSA 2FV5A 3OHOA 3LJTA 2J83A 3LILA 4R3VA 3LQ0A 2RJPA 3F17A 3WV2A 1YP1A 1GXDA 3KEKA 4GWMA 5I43A 1C7KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I1I P;  1D8F A;  1KUH A;  4PKS A;  2FV9 A;  3V96 B;  1KUG A;  2D1O A;  3K7N A;  4JIJ A;  1MNC A;  1Y8J A;  1KAP P;  1D5J A;  4GWN A;  1K7Q A;  2AYK A;  4DPE A;  1KBC A;  4FXY P;  1FBL A;  1HOV A;  3TS4 A;  1C8T A;  3KMC A;  3F16 A;  2DW0 A;  1CGF A;  3KEC A;  5CUH A;  2WO8 A;  4A7B A;  1DTH A;  1IAG A;  3B2Z A;  2J0T A;  3Q2G A;  1JK3 A;  1BZS A;  1K7I A;  1XFZ A;  3LUN A;  1ND1 A;  2JSD A;  4EFS A;  3B8Z A;  1BQQ M;  1JH1 A;  1ZVX A;  1XFX A;  1G49 A;  2WOA A;  3F18 A;  1WNI A;  1SLN A;  4CTH A;  2ERO A;  4GQL A;  3LK8 A;  2OZR A;  2MZE A;  3G42 A;  1SMP A;  1MMB A;  2OXZ A;  4HX3 A;  3KWV C;  1OM6 A;  2W15 A;  2E3X A;  3LE9 A;  1QJI A;  4DF9 A;  1R1I A;  5L7F A;  1IAE A;  2W14 A;  1IAB A;  3ZUK A;  3ZVS A;  1Q3A A;  4XM7 A;  3HDA P;  2X7M A;  2RJQ A;  1ZS0 A;  1RM8 A;  4H49 A;  4J4M A;  1DMT A;  3WV3 A;  1XUR A;  4GR0 A;  2O3E A;  1R55 A;  4L6T A;  1PWQ A;  1PWU A;  1C3I A;  5I4O A;  4GF1 A;  4I35 A;  4H1Q A;  1GKD A;  2JT5 A;  1YQY A;  3O64 A;  1GE6 A;  2OY4 A;  1OM8 A;  1SU3 A;  2Y6C A;  2OW2 A;  5D1U A;  1CXV A;  3KHI A;  1HTD A;  3OHL A;  2USN A;  2MLS A;  1FLS A;  3EDZ A;  1ZTQ A;  3LQB A;  3E8R A;  1JKY A;  1KUK A;  1UMS A;  3LGP A;  1ATL A;  1ZP5 A;  3HBV P;  2CKI A;  2K2G A;  1GE7 A;  4PKV A;  3TVC A;  4H30 A;  1BQO A;  1USN A;  3DL1 A;  966C A;  3BA0 A;  3F19 A;  2DW1 A;  3LKA A;  1B3D A;  1BKC I;  1G4K A;  5I2Z A;  1MMP A;  2N8R A;  3EWJ A;  4ILW D;  2JT6 A;  1GE5 A;  2PJT A;  4XBH A;  1RMZ A;  3KME A;  2OI0 A;  1FM1 A;  1GKC A;  1Y0V A;  1BUV M;  1KUI A;  1OM7 A;  4ON1 A;  3HYG A;  1BM6 A;  4H2E A;  4JPA A;  1XFU A;  2X3C A;  3ZXH A;  1J7N A;  1BKC E;  3O2X A;  3TSK A;  5D1S A;  4GUY A;  2Y6D A;  1A86 A;  1R1J A;  4AIG A;  3DNG A;  1OMJ A;  3LEA A;  1KUF A;  1XUC A;  1JAO A;  3HY9 A;  1EB6 A;  1QUA A;  2OW1 A;  2JIH A;  3EHY A;  3L0T A;  1SAT A;  3RTT A;  3DWB A;  3LIK A;  5L79 A;  4PKQ A;  4G9L A;  3ELM A;  1JAP A;  2DDY A;  3P1V A;  5D3C A;  1K7G A;  1XFV A;  3P24 A;  3AIG A;  5D7W A;  1I73 A;  3DPF A;  3NX7 A;  4XM6 A;  1L6J A;  1D8M A;  2OXW A;  1HY7 A;  5JMY A;  1JAN A;  4GR3 A;  1GO7 P;  2X3B A;  3AYU A;  4FU4 A;  3HB2 P;  2WO9 A;  1BSW A;  4AXQ A;  4AUO A;  4PKW A;  3F1A A;  4L63 A;  5BOY A;  3LJG A;  1Z3J A;  4QKZ A;  5CZM A;  1BUD A;  2OVZ A;  3WV1 A;  1JJ9 A;  4L19 A;  1EUB A;  3DPE A;  3I7G A;  4ZR5 A;  3LMC A;  3L0V A;  2I47 A;  3EDH A;  3I7I A;  4H76 A;  2K9C A;  1SLM A;  1JIZ A;  2ERP A;  1SRP A;  1JAQ A;  4JP4 A;  1CGE A;  1JIW P;  3HBU P;  2E2D A;  2XS3 A;  4WF6 A;  2MZH A;  2HU6 A;  3F15 A;  3GBO A;  4WK7 A;  1MMQ A;  5BOT A;  1ZXC A;  2QPJ A;  5I3M A;  1HFC A;  1I76 A;  3DSL A;  5D1T A;  4A3W A;  3VTG A;  4AYK A;  1A85 A;  2OW9 A;  2W0D A;  1EAK A;  4Q1L A;  1CIZ A;  3HY7 A;  2XS4 A;  1O0T A;  3KEJ A;  2JNP A;  4FVL A;  5I12 A;  1XFY A;  3K7L A;  1CK7 A;  1AKL A;  1G9K A;  2D1N A;  1ZXV A;  4WKE A;  1IAD A;  3EDI A;  2Z2D A;  1AF0 A;  1CGL A;  4PKU A;  4PKR A;  1UEA A;  1UTT A;  1O0Q A;  1G12 A;  5H8X A;  2OXU A;  2W12 A;  1OO9 A;  4IUW A;  3N2V A;  1HFS A;  4G0D A;  4WZV A;  1XFW A;  3B92 A;  1R54 A;  2W13 A;  1R1H A;  4DD8 A;  1B8Y A;  1QIB A;  1GO8 P;  2O36 A;  2YB9 A;  3SHI A;  3VI1 A;  4XM8 A;  1BIW A;  1OS2 A;  5I0L A;  1OS9 A;  4JQG A;  1AST A;  1PWW A;  1UTZ A;  2TCL A;  3N2U A;  1YCM A;  2OY2 A;  5B5O A;  1QJJ A;  2KRJ A;  830C A;  2DW2 A;  2DDF A;  4H3X A;  3CKI A;  3EDG A;  2POJ A;  2OVX A;  1CAQ A;  4XCT A;  5B5P A;  5CXA A;  456C A;  2AIG P;  1YOU A;  3USN A;  4I03 A;  1HV5 A;  4H82 A;  4PKT A;  1UMT A;  3EHX A;  1QIA A;  1IAC A;  5D2B A;  1MMR A;  2ERQ A;  1BKC A;  1Y93 A;  2MZI A;  2CLT A;  1PWV A;  5BPA A;  1S4B P;  4IN9 A;  3RTS A;  3Q2H A;  3UVC A;  1H71 P;  4JA1 A;  2SRT A;  2MLR A;  5LAB A;  2A8H A;  1XUD A;  3TT4 A;  3AYK A;  3U1R A;  2OW0 A;  1IAA A;  4H84 A;  4HMA A;  1G05 A;  2L0R A;  1AYK A;  1D7X A;  4WKI A;  4FXQ A;  1CQR A;  2V4B A;  1QIC A;  3LJZ A;  2YIG A;  1PWP A;  3G5C A;  3MA2 A;  3LUM A;  2X3A A;  3LIR A;  3KRY A;  4IJO A;  3HDB A;  4GR8 A;  4DV8 A;  1ROS A;  2FV5 A;  3OHO A;  3LJT A;  2J83 A;  3LIL A;  4R3V A;  3LQ0 A;  2RJP A;  3F17 A;  3WV2 A;  1YP1 A;  1GXD A;  3KEK A;  4GWM A;  5I43 A;  1C7K A; 
#chains in the Genus database with same CATH topology
 3DTK A;  1I1I P;  1D8F A;  1KUH A;  4PKS A;  2FV9 A;  3V96 B;  3DTI A;  1KUG A;  2D1O A;  3K7N A;  4JIJ A;  1MNC A;  1Y8J A;  1KAP P;  1D5J A;  4GWN A;  1K7Q A;  2AYK A;  4DPE A;  1KBC A;  4FXY P;  1FBL A;  1HOV A;  3TS4 A;  1C8T A;  3KMC A;  3F16 A;  2DW0 A;  1CGF A;  3KEC A;  5CUH A;  2WO8 A;  4A7B A;  1DTH A;  1IAG A;  3B2Z A;  2J0T A;  3Q2G A;  1JK3 A;  1BZS A;  1K7I A;  1XFZ A;  3LUN A;  1ND1 A;  2JSD A;  4EFS A;  3B8Z A;  1BQQ M;  1JH1 A;  1ZVX A;  1XFX A;  1G49 A;  2WOA A;  3F18 A;  1WNI A;  1SLN A;  4CTH A;  2ERO A;  4GQL A;  3LK8 A;  2OZR A;  2MZE A;  3G42 A;  1SMP A;  1MMB A;  2OXZ A;  4HX3 A;  3KWV C;  1OM6 A;  2W15 A;  2E3X A;  3LE9 A;  1QJI A;  4DF9 A;  1R1I A;  5L7F A;  1IAE A;  2W14 A;  1IAB A;  3ZUK A;  3ZVS A;  1Q3A A;  4XM7 A;  1XAX A;  3HDA P;  2X7M A;  2RJQ A;  1ZS0 A;  1RM8 A;  4H49 A;  4J4M A;  1DMT A;  3WV3 A;  1XUR A;  4GR0 A;  2O3E A;  1R55 A;  4L6T A;  1PWQ A;  1PWU A;  1C3I A;  5I4O A;  4GF1 A;  4I35 A;  4H1Q A;  1GKD A;  2JT5 A;  1YQY A;  3O64 A;  1GE6 A;  2OY4 A;  1OM8 A;  1SU3 A;  2Y6C A;  2OW2 A;  5D1U A;  1CXV A;  3KHI A;  1HTD A;  3OHL A;  2USN A;  2MLS A;  1FLS A;  3EDZ A;  1ZTQ A;  3LQB A;  3E8R A;  1JKY A;  1KUK A;  1UMS A;  3LGP A;  1ATL A;  1ZP5 A;  3HBV P;  2CKI A;  2K2G A;  1GE7 A;  4PKV A;  3TVC A;  4H30 A;  1BQO A;  1USN A;  3DL1 A;  966C A;  3BA0 A;  3F19 A;  2DW1 A;  3LKA A;  1B3D A;  1BKC I;  1G4K A;  5I2Z A;  1MMP A;  2N8R A;  3EWJ A;  4ILW D;  2JT6 A;  1GE5 A;  2PJT A;  4XBH A;  1RMZ A;  3KME A;  2OI0 A;  1FM1 A;  1GKC A;  1Y0V A;  1BUV M;  1KUI A;  1OM7 A;  4ON1 A;  3HYG A;  1BM6 A;  4H2E A;  4JPA A;  1XFU A;  2X3C A;  3ZXH A;  1J7N A;  1BKC E;  3O2X A;  3TSK A;  5D1S A;  4GUY A;  2Y6D A;  1A86 A;  1R1J A;  4AIG A;  3DNG A;  3DTE A;  1OMJ A;  3LEA A;  1KUF A;  1XUC A;  1JAO A;  3HY9 A;  1EB6 A;  1QUA A;  2OW1 A;  2JIH A;  3EHY A;  3L0T A;  1SAT A;  3RTT A;  3DWB A;  3LIK A;  5L79 A;  4PKQ A;  4G9L A;  3ELM A;  1JAP A;  2DDY A;  3P1V A;  5D3C A;  1K7G A;  1XFV A;  3P24 A;  3AIG A;  5D7W A;  1I73 A;  3DPF A;  3NX7 A;  4XM6 A;  1L6J A;  1D8M A;  2OXW A;  1HY7 A;  4L7A A;  1JAN A;  5JMY A;  4GR3 A;  1GO7 P;  2X3B A;  3AYU A;  4FU4 A;  3HB2 P;  2WO9 A;  1BSW A;  4AXQ A;  4AUO A;  4PKW A;  3F1A A;  4L63 A;  5BOY A;  3LJG A;  1Z3J A;  4QKZ A;  5CZM A;  1BUD A;  2OVZ A;  3WV1 A;  1JJ9 A;  4L19 A;  1EUB A;  3DPE A;  3I7G A;  4ZR5 A;  3LMC A;  3L0V A;  2I47 A;  3EDH A;  3I7I A;  4H76 A;  2K9C A;  1SLM A;  1JIZ A;  2ERP A;  1SRP A;  1JAQ A;  4JP4 A;  1CGE A;  1JIW P;  3HBU P;  2E2D A;  2XS3 A;  4WF6 A;  2MZH A;  2HU6 A;  3F15 A;  3GBO A;  4WK7 A;  1MMQ A;  5BOT A;  1ZXC A;  2QPJ A;  5I3M A;  1HFC A;  1I76 A;  3DSL A;  5D1T A;  1OZ9 A;  4A3W A;  3VTG A;  4AYK A;  1A85 A;  2OW9 A;  2W0D A;  1EAK A;  4Q1L A;  1CIZ A;  3HY7 A;  2YUF A;  2XS4 A;  1O0T A;  3KEJ A;  2JNP A;  4FVL A;  5I12 A;  1XFY A;  3K7L A;  1CK7 A;  1AKL A;  1G9K A;  2D1N A;  1ZXV A;  4WKE A;  1IAD A;  3EDI A;  2Z2D A;  1AF0 A;  1CGL A;  4PKU A;  4PKR A;  1UEA A;  1UTT A;  1O0Q A;  1G12 A;  5H8X A;  2OXU A;  2W12 A;  1OO9 A;  4IUW A;  3N2V A;  1HFS A;  4G0D A;  4WZV A;  1XFW A;  3B92 A;  1R54 A;  2W13 A;  1R1H A;  4DD8 A;  1B8Y A;  1QIB A;  1GO8 P;  2O36 A;  2YB9 A;  3SHI A;  3VI1 A;  4XM8 A;  1BIW A;  1OS2 A;  5I0L A;  1OS9 A;  4JQG A;  1AST A;  1PWW A;  1UTZ A;  2TCL A;  3N2U A;  1YCM A;  2OY2 A;  5B5O A;  1QJJ A;  2KRJ A;  830C A;  2DW2 A;  2DDF A;  4H3X A;  3CKI A;  3EDG A;  2POJ A;  2OVX A;  1CAQ A;  4XCT A;  5B5P A;  5CXA A;  456C A;  2AIG P;  1YOU A;  3USN A;  4I03 A;  1HV5 A;  4H82 A;  4PKT A;  1UMT A;  3EHX A;  1QIA A;  1IAC A;  5D2B A;  1MMR A;  2ERQ A;  1BKC A;  1Y93 A;  2MZI A;  2CLT A;  1PWV A;  5BPA A;  1S4B P;  4IN9 A;  3RTS A;  3Q2H A;  3UVC A;  1H71 P;  4JA1 A;  2SRT A;  2MLR A;  5LAB A;  2A8H A;  1XUD A;  3TT4 A;  3AYK A;  3U1R A;  2OW0 A;  1IAA A;  4H84 A;  4HMA A;  1G05 A;  2L0R A;  1AYK A;  1D7X A;  4WKI A;  4FXQ A;  1XM5 A;  1CQR A;  2V4B A;  1QIC A;  3LJZ A;  2YIG A;  1PWP A;  3G5C A;  3MA2 A;  3LUM A;  2X3A A;  1TVI A;  3LIR A;  3KRY A;  4IJO A;  3HDB A;  4GR8 A;  4DV8 A;  1ROS A;  2FV5 A;  3OHO A;  3LJT A;  2J83 A;  3LIL A;  4R3V A;  3LQ0 A;  2RJP A;  3F17 A;  3WV2 A;  1YP1 A;  1GXD A;  3KEK A;  4GWM A;  5I43 A;  1C7K A; 
#chains in the Genus database with same CATH homology
 3DTK A;  1I1I P;  1D8F A;  1KUH A;  4PKS A;  2FV9 A;  3V96 B;  3DTI A;  1KUG A;  2D1O A;  3K7N A;  4JIJ A;  1MNC A;  1Y8J A;  1KAP P;  1D5J A;  4GWN A;  1K7Q A;  2AYK A;  4DPE A;  1KBC A;  4FXY P;  1FBL A;  1HOV A;  3TS4 A;  1C8T A;  3KMC A;  3F16 A;  2DW0 A;  1CGF A;  3KEC A;  5CUH A;  2WO8 A;  4A7B A;  1DTH A;  1IAG A;  3B2Z A;  2J0T A;  3Q2G A;  1JK3 A;  1BZS A;  1K7I A;  1XFZ A;  3LUN A;  1ND1 A;  2JSD A;  4EFS A;  3B8Z A;  1BQQ M;  1JH1 A;  1ZVX A;  1XFX A;  1G49 A;  2WOA A;  3F18 A;  1WNI A;  1SLN A;  4CTH A;  2ERO A;  4GQL A;  3LK8 A;  2OZR A;  2MZE A;  3G42 A;  1SMP A;  1MMB A;  2OXZ A;  4HX3 A;  3KWV C;  1OM6 A;  2W15 A;  2E3X A;  3LE9 A;  1QJI A;  4DF9 A;  1R1I A;  5L7F A;  1IAE A;  2W14 A;  1IAB A;  3ZUK A;  3ZVS A;  1Q3A A;  4XM7 A;  3HDA P;  2X7M A;  2RJQ A;  1ZS0 A;  1RM8 A;  4H49 A;  4J4M A;  1DMT A;  3WV3 A;  1XUR A;  4GR0 A;  2O3E A;  1R55 A;  4L6T A;  1PWQ A;  1PWU A;  1C3I A;  5I4O A;  4GF1 A;  4I35 A;  4H1Q A;  1GKD A;  2JT5 A;  1YQY A;  3O64 A;  1GE6 A;  2OY4 A;  1OM8 A;  1SU3 A;  2Y6C A;  2OW2 A;  5D1U A;  1CXV A;  3KHI A;  1HTD A;  3OHL A;  2USN A;  2MLS A;  1FLS A;  3EDZ A;  1ZTQ A;  3LQB A;  3E8R A;  1JKY A;  1KUK A;  1UMS A;  3LGP A;  1ATL A;  1ZP5 A;  3HBV P;  2CKI A;  2K2G A;  1GE7 A;  4PKV A;  3TVC A;  4H30 A;  1BQO A;  1USN A;  3DL1 A;  966C A;  3BA0 A;  3F19 A;  2DW1 A;  3LKA A;  1B3D A;  1BKC I;  1G4K A;  5I2Z A;  1MMP A;  2N8R A;  3EWJ A;  4ILW D;  2JT6 A;  1GE5 A;  2PJT A;  4XBH A;  1RMZ A;  3KME A;  2OI0 A;  1FM1 A;  1GKC A;  1Y0V A;  1BUV M;  1KUI A;  1OM7 A;  4ON1 A;  3HYG A;  1BM6 A;  4H2E A;  4JPA A;  1XFU A;  2X3C A;  3ZXH A;  1J7N A;  1BKC E;  3O2X A;  3TSK A;  5D1S A;  4GUY A;  2Y6D A;  1A86 A;  1R1J A;  4AIG A;  3DNG A;  3DTE A;  1OMJ A;  3LEA A;  1KUF A;  1XUC A;  1JAO A;  3HY9 A;  1EB6 A;  1QUA A;  2OW1 A;  2JIH A;  3EHY A;  3L0T A;  1SAT A;  3RTT A;  3DWB A;  3LIK A;  5L79 A;  4PKQ A;  4G9L A;  3ELM A;  1JAP A;  2DDY A;  3P1V A;  5D3C A;  1K7G A;  1XFV A;  3P24 A;  3AIG A;  5D7W A;  1I73 A;  3DPF A;  3NX7 A;  4XM6 A;  1L6J A;  1D8M A;  2OXW A;  1HY7 A;  4L7A A;  1JAN A;  5JMY A;  4GR3 A;  1GO7 P;  2X3B A;  3AYU A;  4FU4 A;  3HB2 P;  2WO9 A;  1BSW A;  4AXQ A;  4AUO A;  4PKW A;  3F1A A;  4L63 A;  5BOY A;  3LJG A;  1Z3J A;  4QKZ A;  5CZM A;  1BUD A;  2OVZ A;  3WV1 A;  1JJ9 A;  4L19 A;  1EUB A;  3DPE A;  3I7G A;  4ZR5 A;  3LMC A;  3L0V A;  2I47 A;  3EDH A;  3I7I A;  4H76 A;  2K9C A;  1SLM A;  1JIZ A;  2ERP A;  1SRP A;  1JAQ A;  4JP4 A;  1CGE A;  1JIW P;  3HBU P;  2E2D A;  2XS3 A;  4WF6 A;  2MZH A;  2HU6 A;  3F15 A;  3GBO A;  4WK7 A;  1MMQ A;  5BOT A;  1ZXC A;  2QPJ A;  5I3M A;  1HFC A;  1I76 A;  3DSL A;  5D1T A;  4A3W A;  3VTG A;  4AYK A;  1A85 A;  2OW9 A;  2W0D A;  1EAK A;  4Q1L A;  1CIZ A;  3HY7 A;  2YUF A;  2XS4 A;  1O0T A;  3KEJ A;  2JNP A;  4FVL A;  5I12 A;  1XFY A;  3K7L A;  1CK7 A;  1AKL A;  1G9K A;  2D1N A;  1ZXV A;  4WKE A;  1IAD A;  3EDI A;  2Z2D A;  1AF0 A;  1CGL A;  4PKU A;  4PKR A;  1UEA A;  1UTT A;  1O0Q A;  1G12 A;  5H8X A;  2OXU A;  2W12 A;  1OO9 A;  4IUW A;  3N2V A;  1HFS A;  4G0D A;  4WZV A;  1XFW A;  3B92 A;  1R54 A;  2W13 A;  1R1H A;  4DD8 A;  1B8Y A;  1QIB A;  1GO8 P;  2O36 A;  2YB9 A;  3SHI A;  3VI1 A;  4XM8 A;  1BIW A;  1OS2 A;  5I0L A;  1OS9 A;  4JQG A;  1AST A;  1PWW A;  1UTZ A;  2TCL A;  3N2U A;  1YCM A;  2OY2 A;  5B5O A;  1QJJ A;  2KRJ A;  830C A;  2DW2 A;  2DDF A;  4H3X A;  3CKI A;  3EDG A;  2POJ A;  2OVX A;  1CAQ A;  4XCT A;  5B5P A;  5CXA A;  456C A;  2AIG P;  1YOU A;  3USN A;  4I03 A;  1HV5 A;  4H82 A;  4PKT A;  1UMT A;  3EHX A;  1QIA A;  1IAC A;  5D2B A;  1MMR A;  2ERQ A;  1BKC A;  1Y93 A;  2MZI A;  2CLT A;  1PWV A;  5BPA A;  1S4B P;  4IN9 A;  3RTS A;  3Q2H A;  3UVC A;  1H71 P;  4JA1 A;  2SRT A;  2MLR A;  5LAB A;  2A8H A;  1XUD A;  3TT4 A;  3AYK A;  3U1R A;  2OW0 A;  1IAA A;  4H84 A;  4HMA A;  1G05 A;  2L0R A;  1AYK A;  1D7X A;  4WKI A;  4FXQ A;  1CQR A;  2V4B A;  1QIC A;  3LJZ A;  2YIG A;  1PWP A;  3G5C A;  3MA2 A;  3LUM A;  2X3A A;  3LIR A;  3KRY A;  4IJO A;  3HDB A;  4GR8 A;  4DV8 A;  1ROS A;  2FV5 A;  3OHO A;  3LJT A;  2J83 A;  3LIL A;  4R3V A;  3LQ0 A;  2RJP A;  3F17 A;  3WV2 A;  1YP1 A;  1GXD A;  3KEK A;  4GWM A;  5I43 A;  1C7K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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