2I4EA

Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
292
structure length
281
Chain Sequence
KTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGERLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Receptor-type tyrosine-protein phosphatase beta
total genus 102
structure length 281
sequence length 292
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2i4eA00
2QDMA 2AZRA 2VEWA 1BZHA 2HC1A 1OESA 1C87A 3QCIA 1PA9A 4ICZA 2PBNA 4YR8B 2NT2A 2B4UA 3ZV2A 3QCFA 1M3GA 2B4PA 5AWXA 1G1GA 1LARA 2BGDA 4NWFA 2Q47A 2F6ZA 3D1HA 2HNPA 5HDEA 4OHHA 3F99A 4DGPA 1BZJA 5I6VA 1I9TA 2H4GA 3BLTA 2OC3A 2BZLA 2PSZA 4KYRA 4GRZA 3O5XA 1ZC0A 1OHDA 2QEPA 2AHSA 4NX8A 2F6TA 2WGPA 2I6OA 2BGEA 1QZ0A 3EZZA 4QAPA 1C84A 3V0JA 1QXKA 2J17A 3S3HA 5KA2A 4IKCA 2B3OA 1Q6MA 1U24A 2CNIA 2I6JA 1WRMA 1D5RA 2F71A 2CNEA 5KAAA 5EHPA 1P15A 3EAXA 3I7ZA 2CMAA 3F9BA 2I75A 2HVLA 4B04A 1XXPA 1YFOA 2CNFA 4GE2A 1G7FA 4RI4A 4RH5A 4RKKA 1NO6A 1MKPA 5K25A 2P6XA 1JF7A 2OOQA 2M3VA 3RO1A 3QCKA 5BX1A 2HY3A 3ZM3A 2CMBA 4BPCA 2GP0A 5J8RA 2CM7A 3RGQA 1YTSA 1EEOA 4JMKA 4GWFA 4WTYA 1Q1MA 2I4GA 1JLNA 4ZN5A 1PTUA 3AWEA 1GWZA 2J16A 1YWFA 2ESBA 5KACA 1Q6PA 2CNGA 4PYHA 2H02A 2I3UA 2HCMA 2VEXA 1G4US 1AAXA 5K9WA 4NWGA 3F41A 3I80A 5BZZA 4OHIA 1OHEA 1NNYA 3V0GA 1XBOA 2QBQA 3QCGA 2H04A 3BM8A 3QKPA 1I9SA 4RDDA 3AWGA 4KYQA 3GXGA 1XRIA 3QCDA 3QCCA 2G6ZA 1L8GA 2I3RA 1FPRA 1LQFA 2I6MA 1G1FA 1C85A 3A5KA 2CM2A 2NT7A 3RZ2A 1I57A 2SHPA 3EMUA 2I42A 1PTTA 3V0FA 5K22A 3O4TA 5KA3A 1U26A 5KA8A 1OEOX 2Y96A 3QCMA 4AZ1A 3MOWA 1C83A 5K23A 2F70A 2H4KA 4NNDA 4YAAA 1A5YA 3LJ8A 2B4SA 4QUNA 3EB1A 2PI7A 2Q05A 1G4WR 3OMHA 1FPZA 2QCJA 3A5JA 4HJPA 2I5XA 1PTYA 4JMJA 1ONZA 3D1QA 2F46A 5IBSA 3B7OA 3SMEA 3QCEA 2R0BA 1KAKA 4H34A 4J51A 3MOZA 5KA0A 1T4JA 1Q6JA 2MBCA 1XM2A 2QCTA 4D3QA 2QDCA 2C46A 3BRHA 5KA4A 2H4VA 4PVGA 1R6HA 5KADA 3QCBA 2QDPA 2F6VA 2CFVA 4NYHA 1RXDA 4ERCA 2QBSA 4HJQA 4H1OA 3F9AA 4I8NA 1C88A 4RH9A 2BIJA 2OUDA 4GFVA 3BLUA 3M4UA 3S3EA 3O3LA 4R30A 5IBMA 4KI9A 2NZ6A 2OZ5A 2B4OA 4GE6A 3CWEA 1NWLA 2F6YA 4WOHA 3PS5A 4R0SA 3OLRA 2NTAA 1YPTA 4GE5A 1NZ7A 2CJZA 4OHDA 3U96A 2Y2FA 3EU0A 2P4DA 4JNBA 5KABA 3QCNA 3S4OA 4OHLA 1Q6SA 3MMJA 4OHEA 3D44A 1V3AA 5K9VA 1OEMX 5K24A 2I1YA 1OEUA 2VEUA 3GXHA 2VEYA 1NL9A 2GJTA 2VEVA 5M43A 1J4XA 2CMCA 2A3KA 4QBWA 5KA1A 1C86A 1BZCA 5BUGA 2F6FA 3V0IA 1FQ1A 1Q6TA 2PT0A 3D42A 1G7GA 2NV5A 1ZCKA 3ZM0A 2HB1A 2J16B 4ZI4A 1OETA 2B07A 2DXPA 2PA5A 1VHRA 2QBRA 4R0TA 3I36A 3D9CA 2I6IA 1Q6NA 1ZZWA 3QCLA 2ZN7A 1EENA 1YTNA 3V0HA 1GFYA 3S3FA 3O4UA 3O4SA 3S3KA 1ONYA 3QCJA 2I6PA 1T49A 1X24A 2FJMA 2F6WA 2RF6A 2E0TA 3ZMQA 2H03A 2JJDA 4RHGA 4GRYA 1WCHA 1PA1A 1LYVA 4QBEA 2HNQA 2CM8A 2QBPA 3ZMPA 4Z6BA 1PXHA 4QUMA 1YZ4A 2I4HA 1WAXA 4JBCA 3RGOA 2CM3A 4BJOA 4Y14A 1T48A 1KAVA 3H2XA 2GWOA 1ECVA 1L8KA 1YN9A 1G1HA 3AWFA 3V0EA 5MMZB 1RPMA 2I4EA 4WU3A 4QAHA 2FJNA 1YTWA 2B49A 1U25A 5EHRA 3SR9A 5KA9A 2CNHA 3ZM1A 3NMEA 1PH0A 1XXVA 2C7SA 5GTJA 2FH7A 3QCHA 1YGUA 2ZMMA 3S4EA 1PTVA 1NWEA 4ZRTA 3D1OA 4D3RA 1ZCLA 2IMGA 5LXQB 1OEVA 2G59A 1PYNA 3N0AA 3CM3A 3V0DA 2HXPA 4D3PA 2PQ5A 1OHCA 2A8BA 4TVVA 4DGXA 4GFUA 4WU2A 3ZM2A 4GS0A 4HRFA 4MBBA 2BV5A 2HC2A 4S0GA 4RI5A 3QKQA 1SUGA 4Y2EA 3F81A 5KA7A 2YDUA 1YGRA 2NLKA 5BZXA
chains in the Genus database with same CATH superfamily
2QDMA 2AZRA 2VEWA 1BZHA 2HC1A 1OESA 1C87A 3QCIA 1P3DA 1PA9A 4ICZA 2PBNA 4YR8B 2NT2A 2B4UA 3ZV2A 4CVKA 3QCFA 1M3GA 2B4PA 5AWXA 1G1GA 1LARA 2GC5A 2BGDA 4NWFA 1EEHA 2Q47A 2F6ZA 3D1HA 2HNPA 5HDEA 2Y66A 4OHHA 3F99A 4DGPA 1BZJA 5I6VA 1I9TA 2H4GA 3BLTA 2GCAA 2OC3A 2BZLA 2PSZA 4KYRA 4GRZA 3O5XA 1ZC0A 1OHDA 2QEPA 2AHSA 4NX8A 2F6TA 2WGPA 2I6OA 2BGEA 1QZ0A 3EZZA 4QAPA 1C84A 3V0JA 1QXKA 2J17A 3S3HA 3N2AA 5KA2A 4IKCA 2B3OA 1Q6MA 1E0DA 1U24A 2CNIA 2I6JA 1WRMA 1D5RA 1FGSA 2F71A 2CNEA 5KAAA 5EHPA 1P15A 3EAXA 1J6UA 3I7ZA 2CMAA 3F9BA 2I75A 2HVLA 4B04A 1XXPA 1YFOA 2CNFA 4GE2A 1G7FA 4RI4A 4RH5A 4RKKA 1NO6A 1MKPA 4C13A 5K25A 2P6XA 1JF7A 2OOQA 2M3VA 1UAGA 2GC6A 3RO1A 3QCKA 5BX1A 2HY3A 3ZM3A 2CMBA 4BPCA 2GP0A 5J8RA 2CM7A 3RGQA 1YTSA 1EEOA 2AM1A 4BUBA 4JMKA 2JFFA 4GWFA 4WTYA 1Q1MA 2I4GA 1JLNA 2Y1OA 4ZN5A 1PTUA 3AWEA 1GWZA 2J16A 1YWFA 2ESBA 2JFHA 5KACA 1Q6PA 2CNGA 4PYHA 2H02A 2I3UA 2HCMA 2VEXA 1G4US 1AAXA 3MVNA 5K9WA 4NWGA 3F41A 3I80A 5BZZA 4OHIA 3ZM5A 1OHEA 1NNYA 3V0GA 1XBOA 2QBQA 4HV4A 3QCGA 2H04A 3BM8A 3QKPA 1I9SA 4RDDA 3AWGA 4KYQA 3GXGA 1XRIA 3QCDA 3QCCA 2G6ZA 2VTEA 1L8GA 2I3RA 1FPRA 1LQFA 4QF5A 2I6MA 1G1FA 3NRSA 1C85A 3A5KA 2CM2A 2NT7A 3RZ2A 1I57A 2SHPA 3EMUA 2I42A 1PTTA 2VORA 2UUOA 5A5EA 3V0FA 5K22A 3O4TA 5KA3A 1U26A 5KA8A 1OEOX 2Y96A 3QCMA 4AZ1A 3MOWA 4C12A 1P31A 1C83A 4CVMA 5K23A 1JBWA 2F70A 2H4KA 4NNDA 4YAAA 1A5YA 1JBVA 3LJ8A 2B4SA 3LK7A 3EB1A 2PI7A 2Q05A 1G4WR 4QUNA 1FPZA 2QCJA 3OMHA 3A5JA 4HJPA 2I5XA 1PTYA 4JMJA 1ONZA 3D1QA 2F46A 5IBSA 3B7OA 3SMEA 3QCEA 2R0BA 1KAKA 4H34A 4J51A 3MOZA 5KA0A 1T4JA 1Q6JA 2X5OA 2MBCA 1XM2A 2QCTA 4D3QA 2QDCA 2C46A 3BRHA 5KA4A 2H4VA 4PVGA 3ZL8A 1R6HA 4BUCA 5KADA 3QCBA 1GG4A 2QDPA 2F6VA 2CFVA 4NYHA 1RXDA 3QCZA 4ERCA 2QBSA 4HJQA 4H1OA 3F9AA 4I8NA 1C88A 4RH9A 2BIJA 2OUDA 4GFVA 3BLUA 3M4UA 3S3EA 3O3LA 4R30A 5IBMA 4KI9A 2NZ6A 2OZ5A 2Y68A 1W78A 2B4OA 4GE6A 4QDIA 3CWEA 1NWLA 2F6YA 4WOHA 3PS5A 4R0SA 3OLRA 2VTDA 2NTAA 1YPTA 4GE5A 1NZ7A 2WJPA 2CJZA 4OHDA 3U96A 2Y2FA 3EU0A 2P4DA 4JNBA 5KABA 3QCNA 3S4OA 4OHLA 1Q6SA 3MMJA 4OHEA 3D44A 1V3AA 5K9VA 1OEMX 5K24A 2I1YA 1OEUA 2VEUA 3PYZA 4UAGA 2WTZA 3GXHA 2VEYA 2XJAA 1NL9A 2GJTA 2VEVA 5M43A 1J4XA 2CMCA 2A3KA 4QBWA 5KA1A 1C86A 1BZCA 5BUGA 2F6FA 3V0IA 1FQ1A 1Q6TA 2PT0A 3D42A 4CVLA 1G7GA 2NV5A 1ZCKA 2UAGA 3ZM0A 2HB1A 2J16B 1GQYA 4ZI4A 1OETA 2B07A 2DXPA 2PA5A 1VHRA 2F00A 2QBRA 4R0TA 2GCBA 3I36A 2VOSA 3D9CA 2I6IA 1Q6NA 1ZZWA 3QCLA 2ZN7A 1EENA 1YTNA 3V0HA 1GFYA 3S3FA 3O4UA 3O4SA 3S3KA 1ONYA 1E8CA 3QCJA 2I6PA 4ZIYA 1T49A 1X24A 2FJMA 2F6WA 2RF6A 2E0TA 3ZMQA 2H03A 2JJDA 4RHGA 2JFGA 4GRYA 1WCHA 2Y67A 3ZM6A 1PA1A 1LYVA 4QBEA 2HNQA 2CM8A 3UAGA 2QBPA 3ZMPA 4Z6BA 2XPCA 1PXHA 4QUMA 1O5ZA 1YZ4A 1WAXA 2I4HA 4JBCA 3RGOA 2CM3A 4BJOA 4Y14A 1T48A 1KAVA 3H2XA 2GWOA 1ECVA 1GQQA 1L8KA 1YN9A 1G1HA 3AWFA 3V0EA 5MMZB 1RPMA 2I4EA 4WU3A 4QAHA 2FJNA 1YTWA 2B49A 1U25A 5EHRA 3SR9A 5KA9A 5A5FA 2CNHA 3ZM1A 3NMEA 1PH0A 1XXVA 2C7SA 5GTJA 2FH7A 3QCHA 1YGUA 2ZMMA 3S4EA 1PTVA 1NWEA 4ZRTA 3D1OA 4D3RA 1ZCLA 2IMGA 5LXQB 1OEVA 2G59A 2AM2A 1PYNA 3N0AA 3CM3A 3V0DA 2HXPA 4D3PA 2PQ5A 1OHCA 2A8BA 4TVVA 4DGXA 4GFUA 4WU2A 3ZM2A 1W7KA 4GS0A 4HRFA 2UUPA 4MBBA 2BV5A 2HC2A 3HN7A 4S0GA 4RI5A 3QKQA 1SUGA 4Y2EA 3F81A 5KA7A 2YDUA 1YGRA 2NLKA 5BZXA
chains in the Genus database with same CATH topology
2QDMA 2AZRA 2VEWA 1BZHA 2HC1A 1OESA 1C87A 3QCIA 1PA9A 4ICZA 2PBNA 4YR8B 2NT2A 2B4UA 3ZV2A 3QCFA 1M3GA 2B4PA 5AWXA 1G1GA 1LARA 2BGDA 4NWFA 2Q47A 2F6ZA 3D1HA 2HNPA 5HDEA 4OHHA 3F99A 4DGPA 1BZJA 5I6VA 1I9TA 2H4GA 3BLTA 2OC3A 2BZLA 2PSZA 4KYRA 4GRZA 3O5XA 1ZC0A 1OHDA 2QEPA 2AHSA 4NX8A 2F6TA 2WGPA 2I6OA 2BGEA 1QZ0A 3EZZA 4QAPA 1C84A 3V0JA 1QXKA 2J17A 3S3HA 5KA2A 4IKCA 2B3OA 1Q6MA 1U24A 2CNIA 2I6JA 1WRMA 1D5RA 2F71A 2CNEA 5KAAA 5EHPA 1P15A 3EAXA 3I7ZA 2CMAA 3F9BA 2I75A 2HVLA 4B04A 1XXPA 1YFOA 2CNFA 4GE2A 1G7FA 4RI4A 4RH5A 4RKKA 1NO6A 1MKPA 5K25A 2P6XA 1JF7A 2OOQA 2M3VA 3RO1A 3QCKA 5BX1A 2HY3A 3ZM3A 2CMBA 4BPCA 2GP0A 5J8RA 2CM7A 3RGQA 1YTSA 1EEOA 4JMKA 4GWFA 4WTYA 1Q1MA 2I4GA 1JLNA 4ZN5A 1PTUA 3AWEA 1GWZA 2J16A 1YWFA 2ESBA 5KACA 1Q6PA 2CNGA 4PYHA 2H02A 2I3UA 2HCMA 2VEXA 1G4US 1AAXA 5K9WA 4NWGA 3F41A 3I80A 5BZZA 4OHIA 1OHEA 1NNYA 3V0GA 1XBOA 2QBQA 3QCGA 2H04A 3BM8A 3QKPA 1I9SA 4RDDA 3AWGA 4KYQA 3GXGA 1XRIA 3QCDA 3QCCA 2G6ZA 1L8GA 2I3RA 1FPRA 1LQFA 2I6MA 1G1FA 1C85A 3A5KA 2CM2A 2NT7A 3RZ2A 1I57A 2SHPA 3EMUA 2I42A 1PTTA 3V0FA 5K22A 3O4TA 5KA3A 1U26A 5KA8A 1OEOX 2Y96A 3QCMA 4AZ1A 3MOWA 1C83A 5K23A 2F70A 2H4KA 4NNDA 4YAAA 1A5YA 3LJ8A 2B4SA 4QUNA 3EB1A 2PI7A 2Q05A 1G4WR 3OMHA 1FPZA 2QCJA 3A5JA 4HJPA 2I5XA 1PTYA 4JMJA 1ONZA 3D1QA 2F46A 5IBSA 3B7OA 3SMEA 3QCEA 2R0BA 1KAKA 4H34A 4J51A 3MOZA 5KA0A 1T4JA 1Q6JA 2MBCA 1XM2A 2QCTA 4D3QA 2QDCA 2C46A 3BRHA 5KA4A 2H4VA 4PVGA 1R6HA 5KADA 3QCBA 2QDPA 2F6VA 2CFVA 4NYHA 1RXDA 4ERCA 2QBSA 4HJQA 4H1OA 3F9AA 4I8NA 1C88A 4RH9A 2BIJA 2OUDA 4GFVA 3BLUA 3M4UA 3S3EA 3O3LA 4R30A 5IBMA 4KI9A 2NZ6A 2OZ5A 2B4OA 4GE6A 3CWEA 1NWLA 2F6YA 4WOHA 3PS5A 4R0SA 3OLRA 2NTAA 1YPTA 4GE5A 1NZ7A 2CJZA 4OHDA 3U96A 2Y2FA 3EU0A 2P4DA 4JNBA 5KABA 3QCNA 3S4OA 4OHLA 1Q6SA 3MMJA 4OHEA 3D44A 1V3AA 5K9VA 1OEMX 5K24A 2I1YA 1OEUA 2VEUA 3GXHA 2VEYA 1NL9A 2GJTA 2VEVA 5M43A 1J4XA 2CMCA 2A3KA 4QBWA 5KA1A 1C86A 1BZCA 5BUGA 2F6FA 3V0IA 1FQ1A 1Q6TA 2PT0A 3D42A 1G7GA 2NV5A 1ZCKA 3ZM0A 2HB1A 2J16B 4ZI4A 1OETA 2B07A 2DXPA 2PA5A 1VHRA 2QBRA 4R0TA 3I36A 3D9CA 2I6IA 1Q6NA 1ZZWA 3QCLA 2ZN7A 1EENA 1YTNA 3V0HA 1GFYA 3S3FA 3O4UA 3O4SA 3S3KA 1ONYA 3QCJA 2I6PA 1T49A 1X24A 2FJMA 2F6WA 2RF6A 2E0TA 3ZMQA 2H03A 2JJDA 4RHGA 4GRYA 1WCHA 1PA1A 1LYVA 4QBEA 2HNQA 2CM8A 2QBPA 3ZMPA 4Z6BA 1PXHA 4QUMA 1YZ4A 2I4HA 1WAXA 4JBCA 3RGOA 2CM3A 4BJOA 4Y14A 1T48A 1KAVA 3H2XA 2GWOA 1ECVA 1L8KA 1YN9A 1G1HA 3AWFA 3V0EA 5MMZB 1RPMA 2I4EA 4WU3A 4QAHA 2FJNA 1YTWA 2B49A 1U25A 5EHRA 3SR9A 5KA9A 2CNHA 3ZM1A 3NMEA 1PH0A 1XXVA 2C7SA 5GTJA 2FH7A 3QCHA 1YGUA 2ZMMA 3S4EA 1PTVA 1NWEA 4ZRTA 3D1OA 4D3RA 1ZCLA 2IMGA 5LXQB 1OEVA 2G59A 1PYNA 3N0AA 3CM3A 3V0DA 2HXPA 4D3PA 2PQ5A 1OHCA 2A8BA 4TVVA 4DGXA 4GFUA 4WU2A 3ZM2A 4GS0A 4HRFA 4MBBA 2BV5A 2HC2A 4S0GA 4RI5A 3QKQA 1SUGA 4Y2EA 3F81A 5KA7A 2YDUA 1YGRA 2NLKA 5BZXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QDM A;  2AZR A;  2VEW A;  1BZH A;  2HC1 A;  1OES A;  1C87 A;  3QCI A;  1PA9 A;  4ICZ A;  2PBN A;  4YR8 B;  2NT2 A;  2B4U A;  3ZV2 A;  3QCF A;  1M3G A;  2B4P A;  5AWX A;  1G1G A;  1LAR A;  2BGD A;  4NWF A;  2Q47 A;  2F6Z A;  3D1H A;  2HNP A;  5HDE A;  4OHH A;  3F99 A;  4DGP A;  1BZJ A;  5I6V A;  1I9T A;  2H4G A;  3BLT A;  2OC3 A;  2BZL A;  2PSZ A;  4KYR A;  4GRZ A;  3O5X A;  1ZC0 A;  1OHD A;  2QEP A;  2AHS A;  4NX8 A;  2F6T A;  2WGP A;  2I6O A;  2BGE A;  1QZ0 A;  3EZZ A;  4QAP A;  1C84 A;  3V0J A;  1QXK A;  2J17 A;  3S3H A;  5KA2 A;  4IKC A;  2B3O A;  1Q6M A;  1U24 A;  2CNI A;  2I6J A;  1WRM A;  1D5R A;  2F71 A;  2CNE A;  5KAA A;  5EHP A;  1P15 A;  3EAX A;  3I7Z A;  2CMA A;  3F9B A;  2I75 A;  2HVL A;  4B04 A;  1XXP A;  1YFO A;  2CNF A;  4GE2 A;  1G7F A;  4RI4 A;  4RH5 A;  4RKK A;  1NO6 A;  1MKP A;  5K25 A;  2P6X A;  1JF7 A;  2OOQ A;  2M3V A;  3RO1 A;  3QCK A;  5BX1 A;  2HY3 A;  3ZM3 A;  2CMB A;  4BPC A;  2GP0 A;  5J8R A;  2CM7 A;  3RGQ A;  1YTS A;  1EEO A;  4JMK A;  4GWF A;  4WTY A;  1Q1M A;  2I4G A;  1JLN A;  4ZN5 A;  1PTU A;  3AWE A;  1GWZ A;  2J16 A;  1YWF A;  2ESB A;  5KAC A;  1Q6P A;  2CNG A;  4PYH A;  2H02 A;  2I3U A;  2HCM A;  2VEX A;  1G4U S;  1AAX A;  5K9W A;  4NWG A;  3F41 A;  3I80 A;  5BZZ A;  4OHI A;  1OHE A;  1NNY A;  3V0G A;  1XBO A;  2QBQ A;  3QCG A;  2H04 A;  3BM8 A;  3QKP A;  1I9S A;  4RDD A;  3AWG A;  4KYQ A;  3GXG A;  1XRI A;  3QCD A;  3QCC A;  2G6Z A;  1L8G A;  2I3R A;  1FPR A;  1LQF A;  2I6M A;  1G1F A;  1C85 A;  3A5K A;  2CM2 A;  2NT7 A;  3RZ2 A;  1I57 A;  2SHP A;  3EMU A;  2I42 A;  1PTT A;  3V0F A;  5K22 A;  3O4T A;  5KA3 A;  1U26 A;  5KA8 A;  1OEO X;  2Y96 A;  3QCM A;  4AZ1 A;  3MOW A;  1C83 A;  5K23 A;  2F70 A;  2H4K A;  4NND A;  4YAA A;  1A5Y A;  3LJ8 A;  2B4S A;  4QUN A;  3EB1 A;  2PI7 A;  2Q05 A;  1G4W R;  3OMH A;  1FPZ A;  2QCJ A;  3A5J A;  4HJP A;  2I5X A;  1PTY A;  4JMJ A;  1ONZ A;  3D1Q A;  2F46 A;  5IBS A;  3B7O A;  3SME A;  3QCE A;  2R0B A;  1KAK A;  4H34 A;  4J51 A;  3MOZ A;  5KA0 A;  1T4J A;  1Q6J A;  2MBC A;  1XM2 A;  2QCT A;  4D3Q A;  2QDC A;  2C46 A;  3BRH A;  5KA4 A;  2H4V A;  4PVG A;  1R6H A;  5KAD A;  3QCB A;  2QDP A;  2F6V A;  2CFV A;  4NYH A;  1RXD A;  4ERC A;  2QBS A;  4HJQ A;  4H1O A;  3F9A A;  4I8N A;  1C88 A;  4RH9 A;  2BIJ A;  2OUD A;  4GFV A;  3BLU A;  3M4U A;  3S3E A;  3O3L A;  4R30 A;  5IBM A;  4KI9 A;  2NZ6 A;  2OZ5 A;  2B4O A;  4GE6 A;  3CWE A;  1NWL A;  2F6Y A;  4WOH A;  3PS5 A;  4R0S A;  3OLR A;  2NTA A;  1YPT A;  4GE5 A;  1NZ7 A;  2CJZ A;  4OHD A;  3U96 A;  2Y2F A;  3EU0 A;  2P4D A;  4JNB A;  5KAB A;  3QCN A;  3S4O A;  4OHL A;  1Q6S A;  3MMJ A;  4OHE A;  3D44 A;  1V3A A;  5K9V A;  1OEM X;  5K24 A;  2I1Y A;  1OEU A;  2VEU A;  3GXH A;  2VEY A;  1NL9 A;  2GJT A;  2VEV A;  5M43 A;  1J4X A;  2CMC A;  2A3K A;  4QBW A;  5KA1 A;  1C86 A;  1BZC A;  5BUG A;  2F6F A;  3V0I A;  1FQ1 A;  1Q6T A;  2PT0 A;  3D42 A;  1G7G A;  2NV5 A;  1ZCK A;  3ZM0 A;  2HB1 A;  2J16 B;  4ZI4 A;  1OET A;  2B07 A;  2DXP A;  2PA5 A;  1VHR A;  2QBR A;  4R0T A;  3I36 A;  3D9C A;  2I6I A;  1Q6N A;  1ZZW A;  3QCL A;  2ZN7 A;  1EEN A;  1YTN A;  3V0H A;  1GFY A;  3S3F A;  3O4U A;  3O4S A;  3S3K A;  1ONY A;  3QCJ A;  2I6P A;  1T49 A;  1X24 A;  2FJM A;  2F6W A;  2RF6 A;  2E0T A;  3ZMQ A;  2H03 A;  2JJD A;  4RHG A;  4GRY A;  1WCH A;  1PA1 A;  1LYV A;  4QBE A;  2HNQ A;  2CM8 A;  2QBP A;  3ZMP A;  4Z6B A;  1PXH A;  4QUM A;  1YZ4 A;  2I4H A;  1WAX A;  4JBC A;  3RGO A;  2CM3 A;  4BJO A;  4Y14 A;  1T48 A;  1KAV A;  3H2X A;  2GWO A;  1ECV A;  1L8K A;  1YN9 A;  1G1H A;  3AWF A;  3V0E A;  5MMZ B;  1RPM A;  2I4E A;  4WU3 A;  4QAH A;  2FJN A;  1YTW A;  2B49 A;  1U25 A;  5EHR A;  3SR9 A;  5KA9 A;  2CNH A;  3ZM1 A;  3NME A;  1PH0 A;  1XXV A;  2C7S A;  5GTJ A;  2FH7 A;  3QCH A;  1YGU A;  2ZMM A;  3S4E A;  1PTV A;  1NWE A;  4ZRT A;  3D1O A;  4D3R A;  1ZCL A;  2IMG A;  5LXQ B;  1OEV A;  2G59 A;  1PYN A;  3N0A A;  3CM3 A;  3V0D A;  2HXP A;  4D3P A;  2PQ5 A;  1OHC A;  2A8B A;  4TVV A;  4DGX A;  4GFU A;  4WU2 A;  3ZM2 A;  4GS0 A;  4HRF A;  4MBB A;  2BV5 A;  2HC2 A;  4S0G A;  4RI5 A;  3QKQ A;  1SUG A;  4Y2E A;  3F81 A;  5KA7 A;  2YDU A;  1YGR A;  2NLK A;  5BZX A; 
#chains in the Genus database with same CATH topology
 2QDM A;  2AZR A;  2VEW A;  1BZH A;  2HC1 A;  1OES A;  1C87 A;  3QCI A;  1P3D A;  1PA9 A;  4ICZ A;  2PBN A;  4YR8 B;  2NT2 A;  2B4U A;  3ZV2 A;  4CVK A;  3QCF A;  1M3G A;  2B4P A;  5AWX A;  1G1G A;  1LAR A;  2GC5 A;  2BGD A;  4NWF A;  1EEH A;  2Q47 A;  2F6Z A;  3D1H A;  2HNP A;  5HDE A;  2Y66 A;  4OHH A;  3F99 A;  4DGP A;  1BZJ A;  5I6V A;  1I9T A;  2H4G A;  3BLT A;  2GCA A;  2OC3 A;  2BZL A;  2PSZ A;  4KYR A;  4GRZ A;  3O5X A;  1ZC0 A;  1OHD A;  2QEP A;  2AHS A;  4NX8 A;  2F6T A;  2WGP A;  2I6O A;  2BGE A;  1QZ0 A;  3EZZ A;  4QAP A;  1C84 A;  3V0J A;  1QXK A;  2J17 A;  3S3H A;  3N2A A;  5KA2 A;  4IKC A;  2B3O A;  1Q6M A;  1E0D A;  1U24 A;  2CNI A;  2I6J A;  1WRM A;  1D5R A;  1FGS A;  2F71 A;  2CNE A;  5KAA A;  5EHP A;  1P15 A;  3EAX A;  1J6U A;  3I7Z A;  2CMA A;  3F9B A;  2I75 A;  2HVL A;  4B04 A;  1XXP A;  1YFO A;  2CNF A;  4GE2 A;  1G7F A;  4RI4 A;  4RH5 A;  4RKK A;  1NO6 A;  1MKP A;  4C13 A;  5K25 A;  2P6X A;  1JF7 A;  2OOQ A;  2M3V A;  1UAG A;  2GC6 A;  3RO1 A;  3QCK A;  5BX1 A;  2HY3 A;  3ZM3 A;  2CMB A;  4BPC A;  2GP0 A;  5J8R A;  2CM7 A;  3RGQ A;  1YTS A;  1EEO A;  2AM1 A;  4BUB A;  4JMK A;  2JFF A;  4GWF A;  4WTY A;  1Q1M A;  2I4G A;  1JLN A;  2Y1O A;  4ZN5 A;  1PTU A;  3AWE A;  1GWZ A;  2J16 A;  1YWF A;  2ESB A;  2JFH A;  5KAC A;  1Q6P A;  2CNG A;  4PYH A;  2H02 A;  2I3U A;  2HCM A;  2VEX A;  1G4U S;  1AAX A;  3MVN A;  5K9W A;  4NWG A;  3F41 A;  3I80 A;  5BZZ A;  4OHI A;  3ZM5 A;  1OHE A;  1NNY A;  3V0G A;  1XBO A;  2QBQ A;  4HV4 A;  3QCG A;  2H04 A;  3BM8 A;  3QKP A;  1I9S A;  4RDD A;  3AWG A;  4KYQ A;  3GXG A;  1XRI A;  3QCD A;  3QCC A;  2G6Z A;  2VTE A;  1L8G A;  2I3R A;  1FPR A;  1LQF A;  4QF5 A;  2I6M A;  1G1F A;  3NRS A;  1C85 A;  3A5K A;  2CM2 A;  2NT7 A;  3RZ2 A;  1I57 A;  2SHP A;  3EMU A;  2I42 A;  1PTT A;  2VOR A;  2UUO A;  5A5E A;  3V0F A;  5K22 A;  3O4T A;  5KA3 A;  1U26 A;  5KA8 A;  1OEO X;  2Y96 A;  3QCM A;  4AZ1 A;  3MOW A;  4C12 A;  1P31 A;  1C83 A;  4CVM A;  5K23 A;  1JBW A;  2F70 A;  2H4K A;  4NND A;  4YAA A;  1A5Y A;  1JBV A;  3LJ8 A;  2B4S A;  3LK7 A;  3EB1 A;  2PI7 A;  2Q05 A;  1G4W R;  4QUN A;  1FPZ A;  2QCJ A;  3OMH A;  3A5J A;  4HJP A;  2I5X A;  1PTY A;  4JMJ A;  1ONZ A;  3D1Q A;  2F46 A;  5IBS A;  3B7O A;  3SME A;  3QCE A;  2R0B A;  1KAK A;  4H34 A;  4J51 A;  3MOZ A;  5KA0 A;  1T4J A;  1Q6J A;  2X5O A;  2MBC A;  1XM2 A;  2QCT A;  4D3Q A;  2QDC A;  2C46 A;  3BRH A;  5KA4 A;  2H4V A;  4PVG A;  3ZL8 A;  1R6H A;  4BUC A;  5KAD A;  3QCB A;  1GG4 A;  2QDP A;  2F6V A;  2CFV A;  4NYH A;  1RXD A;  3QCZ A;  4ERC A;  2QBS A;  4HJQ A;  4H1O A;  3F9A A;  4I8N A;  1C88 A;  4RH9 A;  2BIJ A;  2OUD A;  4GFV A;  3BLU A;  3M4U A;  3S3E A;  3O3L A;  4R30 A;  5IBM A;  4KI9 A;  2NZ6 A;  2OZ5 A;  2Y68 A;  1W78 A;  2B4O A;  4GE6 A;  4QDI A;  3CWE A;  1NWL A;  2F6Y A;  4WOH A;  3PS5 A;  4R0S A;  3OLR A;  2VTD A;  2NTA A;  1YPT A;  4GE5 A;  1NZ7 A;  2WJP A;  2CJZ A;  4OHD A;  3U96 A;  2Y2F A;  3EU0 A;  2P4D A;  4JNB A;  5KAB A;  3QCN A;  3S4O A;  4OHL A;  1Q6S A;  3MMJ A;  4OHE A;  3D44 A;  1V3A A;  5K9V A;  1OEM X;  5K24 A;  2I1Y A;  1OEU A;  2VEU A;  3PYZ A;  4UAG A;  2WTZ A;  3GXH A;  2VEY A;  2XJA A;  1NL9 A;  2GJT A;  2VEV A;  5M43 A;  1J4X A;  2CMC A;  2A3K A;  4QBW A;  5KA1 A;  1C86 A;  1BZC A;  5BUG A;  2F6F A;  3V0I A;  1FQ1 A;  1Q6T A;  2PT0 A;  3D42 A;  4CVL A;  1G7G A;  2NV5 A;  1ZCK A;  2UAG A;  3ZM0 A;  2HB1 A;  2J16 B;  1GQY A;  4ZI4 A;  1OET A;  2B07 A;  2DXP A;  2PA5 A;  1VHR A;  2F00 A;  2QBR A;  4R0T A;  2GCB A;  3I36 A;  2VOS A;  3D9C A;  2I6I A;  1Q6N A;  1ZZW A;  3QCL A;  2ZN7 A;  1EEN A;  1YTN A;  3V0H A;  1GFY A;  3S3F A;  3O4U A;  3O4S A;  3S3K A;  1ONY A;  1E8C A;  3QCJ A;  2I6P A;  4ZIY A;  1T49 A;  1X24 A;  2FJM A;  2F6W A;  2RF6 A;  2E0T A;  3ZMQ A;  2H03 A;  2JJD A;  4RHG A;  2JFG A;  4GRY A;  1WCH A;  2Y67 A;  3ZM6 A;  1PA1 A;  1LYV A;  4QBE A;  2HNQ A;  2CM8 A;  3UAG A;  2QBP A;  3ZMP A;  4Z6B A;  2XPC A;  1PXH A;  4QUM A;  1O5Z A;  1YZ4 A;  1WAX A;  2I4H A;  4JBC A;  3RGO A;  2CM3 A;  4BJO A;  4Y14 A;  1T48 A;  1KAV A;  3H2X A;  2GWO A;  1ECV A;  1GQQ A;  1L8K A;  1YN9 A;  1G1H A;  3AWF A;  3V0E A;  5MMZ B;  1RPM A;  2I4E A;  4WU3 A;  4QAH A;  2FJN A;  1YTW A;  2B49 A;  1U25 A;  5EHR A;  3SR9 A;  5KA9 A;  5A5F A;  2CNH A;  3ZM1 A;  3NME A;  1PH0 A;  1XXV A;  2C7S A;  5GTJ A;  2FH7 A;  3QCH A;  1YGU A;  2ZMM A;  3S4E A;  1PTV A;  1NWE A;  4ZRT A;  3D1O A;  4D3R A;  1ZCL A;  2IMG A;  5LXQ B;  1OEV A;  2G59 A;  2AM2 A;  1PYN A;  3N0A A;  3CM3 A;  3V0D A;  2HXP A;  4D3P A;  2PQ5 A;  1OHC A;  2A8B A;  4TVV A;  4DGX A;  4GFU A;  4WU2 A;  3ZM2 A;  1W7K A;  4GS0 A;  4HRF A;  2UUP A;  4MBB A;  2BV5 A;  2HC2 A;  3HN7 A;  4S0G A;  4RI5 A;  3QKQ A;  1SUG A;  4Y2E A;  3F81 A;  5KA7 A;  2YDU A;  1YGR A;  2NLK A;  5BZX A; 
#chains in the Genus database with same CATH homology
 2QDM A;  2AZR A;  2VEW A;  1BZH A;  2HC1 A;  1OES A;  1C87 A;  3QCI A;  1PA9 A;  4ICZ A;  2PBN A;  4YR8 B;  2NT2 A;  2B4U A;  3ZV2 A;  3QCF A;  1M3G A;  2B4P A;  5AWX A;  1G1G A;  1LAR A;  2BGD A;  4NWF A;  2Q47 A;  2F6Z A;  3D1H A;  2HNP A;  5HDE A;  4OHH A;  3F99 A;  4DGP A;  1BZJ A;  5I6V A;  1I9T A;  2H4G A;  3BLT A;  2OC3 A;  2BZL A;  2PSZ A;  4KYR A;  4GRZ A;  3O5X A;  1ZC0 A;  1OHD A;  2QEP A;  2AHS A;  4NX8 A;  2F6T A;  2WGP A;  2I6O A;  2BGE A;  1QZ0 A;  3EZZ A;  4QAP A;  1C84 A;  3V0J A;  1QXK A;  2J17 A;  3S3H A;  5KA2 A;  4IKC A;  2B3O A;  1Q6M A;  1U24 A;  2CNI A;  2I6J A;  1WRM A;  1D5R A;  2F71 A;  2CNE A;  5KAA A;  5EHP A;  1P15 A;  3EAX A;  3I7Z A;  2CMA A;  3F9B A;  2I75 A;  2HVL A;  4B04 A;  1XXP A;  1YFO A;  2CNF A;  4GE2 A;  1G7F A;  4RI4 A;  4RH5 A;  4RKK A;  1NO6 A;  1MKP A;  5K25 A;  2P6X A;  1JF7 A;  2OOQ A;  2M3V A;  3RO1 A;  3QCK A;  5BX1 A;  2HY3 A;  3ZM3 A;  2CMB A;  4BPC A;  2GP0 A;  5J8R A;  2CM7 A;  3RGQ A;  1YTS A;  1EEO A;  4JMK A;  4GWF A;  4WTY A;  1Q1M A;  2I4G A;  1JLN A;  4ZN5 A;  1PTU A;  3AWE A;  1GWZ A;  2J16 A;  1YWF A;  2ESB A;  5KAC A;  1Q6P A;  2CNG A;  4PYH A;  2H02 A;  2I3U A;  2HCM A;  2VEX A;  1G4U S;  1AAX A;  5K9W A;  4NWG A;  3F41 A;  3I80 A;  5BZZ A;  4OHI A;  1OHE A;  1NNY A;  3V0G A;  1XBO A;  2QBQ A;  3QCG A;  2H04 A;  3BM8 A;  3QKP A;  1I9S A;  4RDD A;  3AWG A;  4KYQ A;  3GXG A;  1XRI A;  3QCD A;  3QCC A;  2G6Z A;  1L8G A;  2I3R A;  1FPR A;  1LQF A;  2I6M A;  1G1F A;  1C85 A;  3A5K A;  2CM2 A;  2NT7 A;  3RZ2 A;  1I57 A;  2SHP A;  3EMU A;  2I42 A;  1PTT A;  3V0F A;  5K22 A;  3O4T A;  5KA3 A;  1U26 A;  5KA8 A;  1OEO X;  2Y96 A;  3QCM A;  4AZ1 A;  3MOW A;  1C83 A;  5K23 A;  2F70 A;  2H4K A;  4NND A;  4YAA A;  1A5Y A;  3LJ8 A;  2B4S A;  4QUN A;  3EB1 A;  2PI7 A;  2Q05 A;  1G4W R;  3OMH A;  1FPZ A;  2QCJ A;  3A5J A;  4HJP A;  2I5X A;  1PTY A;  4JMJ A;  1ONZ A;  3D1Q A;  2F46 A;  5IBS A;  3B7O A;  3SME A;  3QCE A;  2R0B A;  1KAK A;  4H34 A;  4J51 A;  3MOZ A;  5KA0 A;  1T4J A;  1Q6J A;  2MBC A;  1XM2 A;  2QCT A;  4D3Q A;  2QDC A;  2C46 A;  3BRH A;  5KA4 A;  2H4V A;  4PVG A;  1R6H A;  5KAD A;  3QCB A;  2QDP A;  2F6V A;  2CFV A;  4NYH A;  1RXD A;  4ERC A;  2QBS A;  4HJQ A;  4H1O A;  3F9A A;  4I8N A;  1C88 A;  4RH9 A;  2BIJ A;  2OUD A;  4GFV A;  3BLU A;  3M4U A;  3S3E A;  3O3L A;  4R30 A;  5IBM A;  4KI9 A;  2NZ6 A;  2OZ5 A;  2B4O A;  4GE6 A;  3CWE A;  1NWL A;  2F6Y A;  4WOH A;  3PS5 A;  4R0S A;  3OLR A;  2NTA A;  1YPT A;  4GE5 A;  1NZ7 A;  2CJZ A;  4OHD A;  3U96 A;  2Y2F A;  3EU0 A;  2P4D A;  4JNB A;  5KAB A;  3QCN A;  3S4O A;  4OHL A;  1Q6S A;  3MMJ A;  4OHE A;  3D44 A;  1V3A A;  5K9V A;  1OEM X;  5K24 A;  2I1Y A;  1OEU A;  2VEU A;  3GXH A;  2VEY A;  1NL9 A;  2GJT A;  2VEV A;  5M43 A;  1J4X A;  2CMC A;  2A3K A;  4QBW A;  5KA1 A;  1C86 A;  1BZC A;  5BUG A;  2F6F A;  3V0I A;  1FQ1 A;  1Q6T A;  2PT0 A;  3D42 A;  1G7G A;  2NV5 A;  1ZCK A;  3ZM0 A;  2HB1 A;  2J16 B;  4ZI4 A;  1OET A;  2B07 A;  2DXP A;  2PA5 A;  1VHR A;  2QBR A;  4R0T A;  3I36 A;  3D9C A;  2I6I A;  1Q6N A;  1ZZW A;  3QCL A;  2ZN7 A;  1EEN A;  1YTN A;  3V0H A;  1GFY A;  3S3F A;  3O4U A;  3O4S A;  3S3K A;  1ONY A;  3QCJ A;  2I6P A;  1T49 A;  1X24 A;  2FJM A;  2F6W A;  2RF6 A;  2E0T A;  3ZMQ A;  2H03 A;  2JJD A;  4RHG A;  4GRY A;  1WCH A;  1PA1 A;  1LYV A;  4QBE A;  2HNQ A;  2CM8 A;  2QBP A;  3ZMP A;  4Z6B A;  1PXH A;  4QUM A;  1YZ4 A;  2I4H A;  1WAX A;  4JBC A;  3RGO A;  2CM3 A;  4BJO A;  4Y14 A;  1T48 A;  1KAV A;  3H2X A;  2GWO A;  1ECV A;  1L8K A;  1YN9 A;  1G1H A;  3AWF A;  3V0E A;  5MMZ B;  1RPM A;  2I4E A;  4WU3 A;  4QAH A;  2FJN A;  1YTW A;  2B49 A;  1U25 A;  5EHR A;  3SR9 A;  5KA9 A;  2CNH A;  3ZM1 A;  3NME A;  1PH0 A;  1XXV A;  2C7S A;  5GTJ A;  2FH7 A;  3QCH A;  1YGU A;  2ZMM A;  3S4E A;  1PTV A;  1NWE A;  4ZRT A;  3D1O A;  4D3R A;  1ZCL A;  2IMG A;  5LXQ B;  1OEV A;  2G59 A;  1PYN A;  3N0A A;  3CM3 A;  3V0D A;  2HXP A;  4D3P A;  2PQ5 A;  1OHC A;  2A8B A;  4TVV A;  4DGX A;  4GFU A;  4WU2 A;  3ZM2 A;  4GS0 A;  4HRF A;  4MBB A;  2BV5 A;  2HC2 A;  4S0G A;  4RI5 A;  3QKQ A;  1SUG A;  4Y2E A;  3F81 A;  5KA7 A;  2YDU A;  1YGR A;  2NLK A;  5BZX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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