2I4HA

Structural studies of protein tyrosine phosphatase beta catalytic domain co-crystallized with a sulfamic acid inhibitor
Total Genus 100
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
293
structure length
280
Chain Sequence
KTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Receptor-type tyrosine-protein phosphatase beta
total genus 100
structure length 280
sequence length 293
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2i4hA00
1T4JA 4IKCA 3S3EA 2PI7A 4ZRTA 1L8GA 4WU2A 3QCIA 1JLNA 2QDCA 3BRHA 5M43A 5BX1A 1PA9A 2F6YA 2VEVA 5K24A 1C85A 2I6IA 1R6HA 2BV5A 2F6FA 1YZ4A 1QXKA 4NYHA 3RGQA 3ZMPA 3EMUA 4NNDA 2H02A 2CFVA 1GFYA 2Q47A 3F99A 4RHGA 1QZ0A 2OUDA 2G59A 1Q6SA 1M3GA 2H4GA 1XM2A 3O4UA 4GFVA 3OLRA 4RH9A 2QBRA 3EAXA 1FPRA 4PYHA 2CNFA 3MOZA 2WGPA 2FJMA 2HNQA 3A5JA 3AWGA 4HJQA 1P15A 2CM2A 4QAPA 4YR8B 2H04A 1YPTA 2GJTA 3S4OA 3ZM1A 1RPMA 2QBSA 1C83A 1XBOA 3RGOA 1PTTA 1YFOA 2B4OA 1OHCA 4KI9A 1NZ7A 2I4GA 2FH7A 3QCGA 1T48A 4QUNA 3QCJA 1NWLA 1A5YA 2DXPA 2OOQA 5AWXA 3QKQA 4H34A 5KA7A 3QCKA 3QCBA 1G1FA 5IBSA 2B07A 1KAVA 1C88A 1YTNA 1YWFA 4GWFA 2J16A 3V0JA 5KA8A 3S4EA 4OHIA 3ZMQA 2I3RA 1YGRA 2I6MA 3QCDA 3EZZA 5MMZB 2A3KA 1YN9A 1C84A 3O4TA 1LYVA 2BGEA 1D5RA 3V0GA 2QEPA 3CWEA 1YTWA 1ZCLA 1OETA 2CM8A 1G1GA 4I8NA 4KYRA 3F9AA 4GFUA 2B4SA 3O3LA 4RKKA 2J17A 2GP0A 1EEOA 3I36A 5KACA 3M4UA 4WTYA 1U25A 1I57A 2I3UA 3D9CA 2HXPA 4R0TA 1V3AA 5I6VA 5HDEA 1PA1A 5KA0A 4Z6BA 2H4VA 2HC1A 4BJOA 1EENA 1ECVA 3RZ2A 3S3HA 2NT2A 4DGXA 2NZ6A 3BLUA 4QUMA 2I1YA 1LQFA 1MKPA 4ERCA 2B4PA 2HY3A 1YTSA 5K9WA 5KABA 2ESBA 2F6ZA 1Q6PA 4MBBA 2HC2A 1ONZA 1GWZA 1L8KA 1WAXA 2MBCA 3QCHA 2Q05A 1FPZA 2CNHA 2I4HA 3NMEA 2I42A 1ZCKA 2QBPA 5KA2A 5K25A 2F71A 1BZJA 3V0DA 3ZV2A 1LARA 1PTUA 2I6PA 1OEVA 2PQ5A 2PSZA 4RDDA 3BM8A 2I5XA 1PXHA 2PA5A 4R0SA 1I9SA 3I7ZA 1PH0A 4Y2EA 2CMBA 1BZCA 1BZHA 2E0TA 1C87A 4OHDA 5KADA 4PVGA 2A8BA 2VEWA 2SHPA 2QCJA 1Q6JA 2CM7A 4KYQA 3QCNA 2AHSA 4D3QA 4D3PA 4YAAA 5BZZA 1PTVA 1ZC0A 1RXDA 2HNPA 3F81A 4RH5A 4DGPA 2C46A 1XRIA 3BLTA 4TVVA 4JMJA 4WOHA 4GE5A 3QCCA 3H2XA 3QCLA 3U96A 1OEMX 4QAHA 4GE6A 1ONYA 2F6TA 1Q1MA 3S3KA 3D1QA 4WU3A 3V0EA 4OHEA 1Q6MA 4JMKA 2PBNA 1U24A 3D42A 2QDMA 4BPCA 5KA9A 2F46A 1WRMA 4OHLA 3AWFA 2CNEA 3LJ8A 2I6OA 3QCMA 4GE2A 2I75A 2QCTA 2VEUA 1KAKA 5IBMA 4JNBA 4J51A 1SUGA 3F9BA 2Y96A 2Y2FA 1AAXA 3EB1A 2F6WA 2CNIA 1I9TA 2QBQA 2F70A 3QKPA 2I6JA 2BZLA 3A5KA 1X24A 2NT7A 5KA4A 5GTJA 2BIJA 2ZN7A 3ZM3A 3I80A 3MMJA 2M3VA 2CM3A 2CNGA 2F6VA 3D44A 1PTYA 1Q6TA 3OMHA 2NLKA 2JJDA 5BZXA 3V0IA 4JBCA 5K23A 2VEYA 2OC3A 3ZM2A 2FJNA 5LXQB 1OHDA 3GXHA 3N0AA 3SR9A 1G7GA 2GWOA 3MOWA 4HJPA 4Y14A 3D1OA 1NNYA 2HCMA 2P6XA 3QCEA 3O5XA 2H03A 1OEUA 2PT0A 2NV5A 5KAAA 1XXVA 4GRZA 3V0HA 5BUGA 1NWEA 2HB1A 1J4XA 5J8RA 2P4DA 2CJZA 3V0FA 4OHHA 3AWEA 1G1HA 3F41A 1XXPA 2QDPA 2RF6A 2C7SA 1JF7A 1YGUA 2B4UA 3EU0A 4GS0A 1VHRA 1G4US 2H4KA 5EHRA 2B49A 3B7OA 4ICZA 1OHEA 3S3FA 4AZ1A 1G7FA 4NX8A 4S0GA 1U26A 2BGDA 4ZI4A 4HRFA 5K9VA 4QBEA 2J16B 4QBWA 1OEOX 4H1OA 4B04A 1ZZWA 2HVLA 3O4SA 4NWFA 2CMCA 1NO6A 1C86A 1FQ1A 2B3OA 5KA3A 1PYNA 2AZRA 1NL9A 1T49A 1G4WR 2I4EA 4GRYA 2ZMMA 5KA1A 4R30A 2OZ5A 2VEXA 4D3RA 4NWGA 3CM3A 2NTAA 3PS5A 2R0BA 2YDUA 1OESA 2IMGA 1WCHA 3D1HA 3SMEA 2CMAA 3QCFA 2G6ZA 3ZM0A 5K22A 4RI5A 4RI4A 3GXGA 4ZN5A 3RO1A 1Q6NA 5EHPA
chains in the Genus database with same CATH superfamily
1T4JA 4IKCA 3S3EA 2PI7A 4ZRTA 2X5OA 4ZIYA 1L8GA 4WU2A 3QCIA 1JLNA 2QDCA 1GG4A 3BRHA 5M43A 5BX1A 1EEHA 1PA9A 2F6YA 2VEVA 5K24A 1C85A 2I6IA 1R6HA 2BV5A 2F6FA 1YZ4A 1QXKA 4NYHA 3RGQA 3ZMPA 3EMUA 4NNDA 2H02A 2CFVA 1GFYA 2Q47A 3F99A 4RHGA 1QZ0A 2OUDA 2G59A 1Q6SA 1M3GA 2H4GA 1XM2A 3O4UA 4GFVA 2VTDA 3OLRA 4RH9A 2QBRA 3EAXA 1FPRA 4PYHA 2CNFA 3MOZA 2WGPA 2FJMA 2HNQA 3AWGA 3A5JA 4HJQA 1P15A 2CM2A 4QAPA 4YR8B 2H04A 1YPTA 2GJTA 3S4OA 3ZM1A 1JBWA 1RPMA 2QBSA 1C83A 1XBOA 3RGOA 1PTTA 1YFOA 5A5EA 2B4OA 1OHCA 4KI9A 1NZ7A 2I4GA 2FH7A 3QCGA 1T48A 2Y1OA 4QUNA 3QCJA 1NWLA 1A5YA 2DXPA 2OOQA 3NRSA 5AWXA 3QKQA 4H34A 5KA7A 2F00A 3QCKA 2UAGA 4CVLA 3QCBA 1G1FA 5IBSA 2B07A 1KAVA 1C88A 2GC5A 1YTNA 1YWFA 4GWFA 2J16A 3V0JA 5KA8A 3S4EA 4OHIA 3ZMQA 2I3RA 1YGRA 2I6MA 3EZZA 3QCDA 5MMZB 2A3KA 1YN9A 1C84A 2GC6A 3O4TA 2VTEA 1LYVA 2BGEA 1D5RA 3V0GA 2QEPA 3CWEA 1YTWA 2Y68A 1ZCLA 1OETA 2CM8A 1G1GA 4I8NA 4KYRA 3F9AA 4GFUA 2B4SA 3O3LA 4RKKA 2J17A 2GP0A 1EEOA 3I36A 5KACA 3M4UA 4WTYA 1U25A 1I57A 2I3UA 2WJPA 3D9CA 2HXPA 4R0TA 1V3AA 5I6VA 5HDEA 1PA1A 5KA0A 4Z6BA 2H4VA 2HC1A 4BJOA 1EENA 1ECVA 3RZ2A 3S3HA 2NT2A 4DGXA 2NZ6A 3BLUA 4QUMA 2I1YA 2XPCA 3LK7A 1LQFA 1P31A 1MKPA 4ERCA 2AM1A 2B4PA 1O5ZA 2HY3A 1YTSA 5K9WA 5KABA 2ESBA 2F6ZA 1Q6PA 4MBBA 2HC2A 1E8CA 1ONZA 1GWZA 1L8KA 1WAXA 2MBCA 2Q05A 3QCHA 1FPZA 2CNHA 2I4HA 3NMEA 2I42A 1ZCKA 2JFGA 4BUCA 3UAGA 2QBPA 5KA2A 5K25A 2F71A 1BZJA 2XJAA 3V0DA 3ZV2A 1LARA 3ZL8A 1PTUA 2I6PA 3N2AA 1OEVA 2PQ5A 2PSZA 4RDDA 1P3DA 3BM8A 2I5XA 1PXHA 2PA5A 4R0SA 1I9SA 3I7ZA 1PH0A 4Y2EA 2CMBA 5A5FA 1BZCA 1BZHA 2E0TA 1C87A 4OHDA 5KADA 3ZM6A 4PVGA 2A8BA 2VEWA 1J6UA 2SHPA 2QCJA 1Q6JA 2CM7A 4HV4A 2GCBA 4KYQA 3QCNA 2AHSA 4D3QA 4D3PA 4QDIA 4YAAA 5BZZA 1PTVA 1ZC0A 1RXDA 2HNPA 4C12A 3F81A 4RH5A 4DGPA 2C46A 1XRIA 3BLTA 4TVVA 4JMJA 4WOHA 4GE5A 3QCCA 3H2XA 3QCLA 3U96A 1OEMX 4QAHA 4GE6A 1ONYA 2F6TA 1Q1MA 4CVMA 3S3KA 3D1QA 4WU3A 3V0EA 4OHEA 1Q6MA 3QCZA 4JMKA 3PYZA 2PBNA 1U24A 3D42A 2QDMA 4BPCA 5KA9A 1W78A 2F46A 1WRMA 1W7KA 4OHLA 3AWFA 2CNEA 3LJ8A 2I6OA 3QCMA 4GE2A 2I75A 2QCTA 2VEUA 1KAKA 5IBMA 4JNBA 4J51A 1SUGA 3F9BA 2Y96A 4QF5A 2Y2FA 1AAXA 3ZM5A 3EB1A 2F6WA 2CNIA 1I9TA 2QBQA 2F70A 3QKPA 2I6JA 2BZLA 3A5KA 1X24A 2NT7A 5KA4A 5GTJA 2BIJA 2ZN7A 3ZM3A 3I80A 3MMJA 2M3VA 2CM3A 2CNGA 2F6VA 1JBVA 3D44A 1PTYA 1E0DA 1Q6TA 3OMHA 2NLKA 2JJDA 5BZXA 3HN7A 2VORA 3V0IA 4JBCA 5K23A 2VEYA 1GQYA 2OC3A 3ZM2A 2FJNA 5LXQB 1OHDA 3GXHA 3N0AA 3SR9A 1G7GA 2GWOA 3MOWA 4HJPA 2UUOA 4Y14A 3D1OA 1NNYA 2HCMA 2P6XA 3QCEA 3O5XA 2H03A 1OEUA 2PT0A 2NV5A 5KAAA 1XXVA 4GRZA 3V0HA 3MVNA 2GCAA 5BUGA 1NWEA 2HB1A 2AM2A 1J4XA 5J8RA 2P4DA 2CJZA 3V0FA 4OHHA 3AWEA 1G1HA 3F41A 1XXPA 2QDPA 2RF6A 2C7SA 1JF7A 1YGUA 2B4UA 3EU0A 4GS0A 1VHRA 1G4US 2H4KA 2VOSA 5EHRA 2B49A 3B7OA 4ICZA 1OHEA 3S3FA 4AZ1A 1G7FA 4NX8A 4S0GA 1U26A 4CVKA 2BGDA 4ZI4A 4HRFA 5K9VA 4QBEA 2J16B 4QBWA 1OEOX 1UAGA 4H1OA 4B04A 1ZZWA 2HVLA 3O4SA 2Y67A 2CMCA 4NWFA 4BUBA 1NO6A 1C86A 1FQ1A 1FGSA 4UAGA 2B3OA 5KA3A 1PYNA 2AZRA 1NL9A 1T49A 2Y66A 2WTZA 1G4WR 2I4EA 4GRYA 2ZMMA 5KA1A 4R30A 1GQQA 2OZ5A 2VEXA 4D3RA 4NWGA 3CM3A 2NTAA 4C13A 3PS5A 2R0BA 2YDUA 1OESA 2IMGA 1WCHA 3D1HA 3SMEA 2CMAA 3QCFA 2G6ZA 3ZM0A 5K22A 4RI5A 2JFFA 4RI4A 3GXGA 4ZN5A 3RO1A 1Q6NA 5EHPA 2UUPA 2JFHA
chains in the Genus database with same CATH topology
1T4JA 4IKCA 3S3EA 2PI7A 4ZRTA 1L8GA 4WU2A 3QCIA 1JLNA 2QDCA 3BRHA 5M43A 5BX1A 1PA9A 2F6YA 2VEVA 5K24A 1C85A 2I6IA 1R6HA 2BV5A 2F6FA 1YZ4A 1QXKA 4NYHA 3RGQA 3ZMPA 3EMUA 4NNDA 2H02A 2CFVA 1GFYA 2Q47A 3F99A 4RHGA 1QZ0A 2OUDA 2G59A 1Q6SA 1M3GA 2H4GA 1XM2A 3O4UA 4GFVA 3OLRA 4RH9A 2QBRA 3EAXA 1FPRA 4PYHA 2CNFA 3MOZA 2WGPA 2FJMA 2HNQA 3A5JA 3AWGA 4HJQA 1P15A 2CM2A 4QAPA 4YR8B 2H04A 1YPTA 2GJTA 3S4OA 3ZM1A 1RPMA 2QBSA 1C83A 1XBOA 3RGOA 1PTTA 1YFOA 2B4OA 1OHCA 4KI9A 1NZ7A 2I4GA 2FH7A 3QCGA 1T48A 4QUNA 3QCJA 1NWLA 1A5YA 2DXPA 2OOQA 5AWXA 3QKQA 4H34A 5KA7A 3QCKA 3QCBA 1G1FA 5IBSA 2B07A 1KAVA 1C88A 1YTNA 1YWFA 4GWFA 2J16A 3V0JA 5KA8A 3S4EA 4OHIA 3ZMQA 2I3RA 1YGRA 2I6MA 3QCDA 3EZZA 5MMZB 2A3KA 1YN9A 1C84A 3O4TA 1LYVA 2BGEA 1D5RA 3V0GA 2QEPA 3CWEA 1YTWA 1ZCLA 1OETA 2CM8A 1G1GA 4I8NA 4KYRA 3F9AA 4GFUA 2B4SA 3O3LA 4RKKA 2J17A 2GP0A 1EEOA 3I36A 5KACA 3M4UA 4WTYA 1U25A 1I57A 2I3UA 3D9CA 2HXPA 4R0TA 1V3AA 5I6VA 5HDEA 1PA1A 5KA0A 4Z6BA 2H4VA 2HC1A 4BJOA 1EENA 1ECVA 3RZ2A 3S3HA 2NT2A 4DGXA 2NZ6A 3BLUA 4QUMA 2I1YA 1LQFA 1MKPA 4ERCA 2B4PA 2HY3A 1YTSA 5K9WA 5KABA 2ESBA 2F6ZA 1Q6PA 4MBBA 2HC2A 1ONZA 1GWZA 1L8KA 1WAXA 2MBCA 3QCHA 2Q05A 1FPZA 2CNHA 2I4HA 3NMEA 2I42A 1ZCKA 2QBPA 5KA2A 5K25A 2F71A 1BZJA 3V0DA 3ZV2A 1LARA 1PTUA 2I6PA 1OEVA 2PQ5A 2PSZA 4RDDA 3BM8A 2I5XA 1PXHA 2PA5A 4R0SA 1I9SA 3I7ZA 1PH0A 4Y2EA 2CMBA 1BZCA 1BZHA 2E0TA 1C87A 4OHDA 5KADA 4PVGA 2A8BA 2VEWA 2SHPA 2QCJA 1Q6JA 2CM7A 4KYQA 3QCNA 2AHSA 4D3QA 4D3PA 4YAAA 5BZZA 1PTVA 1ZC0A 1RXDA 2HNPA 3F81A 4RH5A 4DGPA 2C46A 1XRIA 3BLTA 4TVVA 4JMJA 4WOHA 4GE5A 3QCCA 3H2XA 3QCLA 3U96A 1OEMX 4QAHA 4GE6A 1ONYA 2F6TA 1Q1MA 3S3KA 3D1QA 4WU3A 3V0EA 4OHEA 1Q6MA 4JMKA 2PBNA 1U24A 3D42A 2QDMA 4BPCA 5KA9A 2F46A 1WRMA 4OHLA 3AWFA 2CNEA 3LJ8A 2I6OA 3QCMA 4GE2A 2I75A 2QCTA 2VEUA 1KAKA 5IBMA 4JNBA 4J51A 1SUGA 3F9BA 2Y96A 2Y2FA 1AAXA 3EB1A 2F6WA 2CNIA 1I9TA 2QBQA 2F70A 3QKPA 2I6JA 2BZLA 3A5KA 1X24A 2NT7A 5KA4A 5GTJA 2BIJA 2ZN7A 3ZM3A 3I80A 3MMJA 2M3VA 2CM3A 2CNGA 2F6VA 3D44A 1PTYA 1Q6TA 3OMHA 2NLKA 2JJDA 5BZXA 3V0IA 4JBCA 5K23A 2VEYA 2OC3A 3ZM2A 2FJNA 5LXQB 1OHDA 3GXHA 3N0AA 3SR9A 1G7GA 2GWOA 3MOWA 4HJPA 4Y14A 3D1OA 1NNYA 2HCMA 2P6XA 3QCEA 3O5XA 2H03A 1OEUA 2PT0A 2NV5A 5KAAA 1XXVA 4GRZA 3V0HA 5BUGA 1NWEA 2HB1A 1J4XA 5J8RA 2P4DA 2CJZA 3V0FA 4OHHA 3AWEA 1G1HA 3F41A 1XXPA 2QDPA 2RF6A 2C7SA 1JF7A 1YGUA 2B4UA 3EU0A 4GS0A 1VHRA 1G4US 2H4KA 5EHRA 2B49A 3B7OA 4ICZA 1OHEA 3S3FA 4AZ1A 1G7FA 4NX8A 4S0GA 1U26A 2BGDA 4ZI4A 4HRFA 5K9VA 4QBEA 2J16B 4QBWA 1OEOX 4H1OA 4B04A 1ZZWA 2HVLA 3O4SA 4NWFA 2CMCA 1NO6A 1C86A 1FQ1A 2B3OA 5KA3A 1PYNA 2AZRA 1NL9A 1T49A 1G4WR 2I4EA 4GRYA 2ZMMA 5KA1A 4R30A 2OZ5A 2VEXA 4D3RA 4NWGA 3CM3A 2NTAA 3PS5A 2R0BA 2YDUA 1OESA 2IMGA 1WCHA 3D1HA 3SMEA 2CMAA 3QCFA 2G6ZA 3ZM0A 5K22A 4RI5A 4RI4A 3GXGA 4ZN5A 3RO1A 1Q6NA 5EHPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T4J A;  4IKC A;  3S3E A;  2PI7 A;  4ZRT A;  1L8G A;  4WU2 A;  3QCI A;  1JLN A;  2QDC A;  3BRH A;  5M43 A;  5BX1 A;  1PA9 A;  2F6Y A;  2VEV A;  5K24 A;  1C85 A;  2I6I A;  1R6H A;  2BV5 A;  2F6F A;  1YZ4 A;  1QXK A;  4NYH A;  3RGQ A;  3ZMP A;  3EMU A;  4NND A;  2H02 A;  2CFV A;  1GFY A;  2Q47 A;  3F99 A;  4RHG A;  1QZ0 A;  2OUD A;  2G59 A;  1Q6S A;  1M3G A;  2H4G A;  1XM2 A;  3O4U A;  4GFV A;  3OLR A;  4RH9 A;  2QBR A;  3EAX A;  1FPR A;  4PYH A;  2CNF A;  3MOZ A;  2WGP A;  2FJM A;  2HNQ A;  3A5J A;  3AWG A;  4HJQ A;  1P15 A;  2CM2 A;  4QAP A;  4YR8 B;  2H04 A;  1YPT A;  2GJT A;  3S4O A;  3ZM1 A;  1RPM A;  2QBS A;  1C83 A;  1XBO A;  3RGO A;  1PTT A;  1YFO A;  2B4O A;  1OHC A;  4KI9 A;  1NZ7 A;  2I4G A;  2FH7 A;  3QCG A;  1T48 A;  4QUN A;  3QCJ A;  1NWL A;  1A5Y A;  2DXP A;  2OOQ A;  5AWX A;  3QKQ A;  4H34 A;  5KA7 A;  3QCK A;  3QCB A;  1G1F A;  5IBS A;  2B07 A;  1KAV A;  1C88 A;  1YTN A;  1YWF A;  4GWF A;  2J16 A;  3V0J A;  5KA8 A;  3S4E A;  4OHI A;  3ZMQ A;  2I3R A;  1YGR A;  2I6M A;  3QCD A;  3EZZ A;  5MMZ B;  2A3K A;  1YN9 A;  1C84 A;  3O4T A;  1LYV A;  2BGE A;  1D5R A;  3V0G A;  2QEP A;  3CWE A;  1YTW A;  1ZCL A;  1OET A;  2CM8 A;  1G1G A;  4I8N A;  4KYR A;  3F9A A;  4GFU A;  2B4S A;  3O3L A;  4RKK A;  2J17 A;  2GP0 A;  1EEO A;  3I36 A;  5KAC A;  3M4U A;  4WTY A;  1U25 A;  1I57 A;  2I3U A;  3D9C A;  2HXP A;  4R0T A;  1V3A A;  5I6V A;  5HDE A;  1PA1 A;  5KA0 A;  4Z6B A;  2H4V A;  2HC1 A;  4BJO A;  1EEN A;  1ECV A;  3RZ2 A;  3S3H A;  2NT2 A;  4DGX A;  2NZ6 A;  3BLU A;  4QUM A;  2I1Y A;  1LQF A;  1MKP A;  4ERC A;  2B4P A;  2HY3 A;  1YTS A;  5K9W A;  5KAB A;  2ESB A;  2F6Z A;  1Q6P A;  4MBB A;  2HC2 A;  1ONZ A;  1GWZ A;  1L8K A;  1WAX A;  2MBC A;  3QCH A;  2Q05 A;  1FPZ A;  2CNH A;  2I4H A;  3NME A;  2I42 A;  1ZCK A;  2QBP A;  5KA2 A;  5K25 A;  2F71 A;  1BZJ A;  3V0D A;  3ZV2 A;  1LAR A;  1PTU A;  2I6P A;  1OEV A;  2PQ5 A;  2PSZ A;  4RDD A;  3BM8 A;  2I5X A;  1PXH A;  2PA5 A;  4R0S A;  1I9S A;  3I7Z A;  1PH0 A;  4Y2E A;  2CMB A;  1BZC A;  1BZH A;  2E0T A;  1C87 A;  4OHD A;  5KAD A;  4PVG A;  2A8B A;  2VEW A;  2SHP A;  2QCJ A;  1Q6J A;  2CM7 A;  4KYQ A;  3QCN A;  2AHS A;  4D3Q A;  4D3P A;  4YAA A;  5BZZ A;  1PTV A;  1ZC0 A;  1RXD A;  2HNP A;  3F81 A;  4RH5 A;  4DGP A;  2C46 A;  1XRI A;  3BLT A;  4TVV A;  4JMJ A;  4WOH A;  4GE5 A;  3QCC A;  3H2X A;  3QCL A;  3U96 A;  1OEM X;  4QAH A;  4GE6 A;  1ONY A;  2F6T A;  1Q1M A;  3S3K A;  3D1Q A;  4WU3 A;  3V0E A;  4OHE A;  1Q6M A;  4JMK A;  2PBN A;  1U24 A;  3D42 A;  2QDM A;  4BPC A;  5KA9 A;  2F46 A;  1WRM A;  4OHL A;  3AWF A;  2CNE A;  3LJ8 A;  2I6O A;  3QCM A;  4GE2 A;  2I75 A;  2QCT A;  2VEU A;  1KAK A;  5IBM A;  4JNB A;  4J51 A;  1SUG A;  3F9B A;  2Y96 A;  2Y2F A;  1AAX A;  3EB1 A;  2F6W A;  2CNI A;  1I9T A;  2QBQ A;  2F70 A;  3QKP A;  2I6J A;  2BZL A;  3A5K A;  1X24 A;  2NT7 A;  5KA4 A;  5GTJ A;  2BIJ A;  2ZN7 A;  3ZM3 A;  3I80 A;  3MMJ A;  2M3V A;  2CM3 A;  2CNG A;  2F6V A;  3D44 A;  1PTY A;  1Q6T A;  3OMH A;  2NLK A;  2JJD A;  5BZX A;  3V0I A;  4JBC A;  5K23 A;  2VEY A;  2OC3 A;  3ZM2 A;  2FJN A;  5LXQ B;  1OHD A;  3GXH A;  3N0A A;  3SR9 A;  1G7G A;  2GWO A;  3MOW A;  4HJP A;  4Y14 A;  3D1O A;  1NNY A;  2HCM A;  2P6X A;  3QCE A;  3O5X A;  2H03 A;  1OEU A;  2PT0 A;  2NV5 A;  5KAA A;  1XXV A;  4GRZ A;  3V0H A;  5BUG A;  1NWE A;  2HB1 A;  1J4X A;  5J8R A;  2P4D A;  2CJZ A;  3V0F A;  4OHH A;  3AWE A;  1G1H A;  3F41 A;  1XXP A;  2QDP A;  2RF6 A;  2C7S A;  1JF7 A;  1YGU A;  2B4U A;  3EU0 A;  4GS0 A;  1VHR A;  1G4U S;  2H4K A;  5EHR A;  2B49 A;  3B7O A;  4ICZ A;  1OHE A;  3S3F A;  4AZ1 A;  1G7F A;  4NX8 A;  4S0G A;  1U26 A;  2BGD A;  4ZI4 A;  4HRF A;  5K9V A;  4QBE A;  2J16 B;  4QBW A;  1OEO X;  4H1O A;  4B04 A;  1ZZW A;  2HVL A;  3O4S A;  4NWF A;  2CMC A;  1NO6 A;  1C86 A;  1FQ1 A;  2B3O A;  5KA3 A;  1PYN A;  2AZR A;  1NL9 A;  1T49 A;  1G4W R;  2I4E A;  4GRY A;  2ZMM A;  5KA1 A;  4R30 A;  2OZ5 A;  2VEX A;  4D3R A;  4NWG A;  3CM3 A;  2NTA A;  3PS5 A;  2R0B A;  2YDU A;  1OES A;  2IMG A;  1WCH A;  3D1H A;  3SME A;  2CMA A;  3QCF A;  2G6Z A;  3ZM0 A;  5K22 A;  4RI5 A;  4RI4 A;  3GXG A;  4ZN5 A;  3RO1 A;  1Q6N A;  5EHP A; 
#chains in the Genus database with same CATH topology
 1T4J A;  4IKC A;  3S3E A;  2PI7 A;  4ZRT A;  2X5O A;  4ZIY A;  1L8G A;  4WU2 A;  3QCI A;  1JLN A;  2QDC A;  1GG4 A;  3BRH A;  5M43 A;  5BX1 A;  1EEH A;  1PA9 A;  2F6Y A;  2VEV A;  5K24 A;  1C85 A;  2I6I A;  1R6H A;  2BV5 A;  2F6F A;  1YZ4 A;  1QXK A;  4NYH A;  3RGQ A;  3ZMP A;  3EMU A;  4NND A;  2H02 A;  2CFV A;  1GFY A;  2Q47 A;  3F99 A;  4RHG A;  1QZ0 A;  2OUD A;  2G59 A;  1Q6S A;  1M3G A;  2H4G A;  1XM2 A;  3O4U A;  4GFV A;  2VTD A;  3OLR A;  4RH9 A;  2QBR A;  3EAX A;  1FPR A;  4PYH A;  2CNF A;  3MOZ A;  2WGP A;  2FJM A;  2HNQ A;  3AWG A;  3A5J A;  4HJQ A;  1P15 A;  2CM2 A;  4QAP A;  4YR8 B;  2H04 A;  1YPT A;  2GJT A;  3S4O A;  3ZM1 A;  1JBW A;  1RPM A;  2QBS A;  1C83 A;  1XBO A;  3RGO A;  1PTT A;  1YFO A;  5A5E A;  2B4O A;  1OHC A;  4KI9 A;  1NZ7 A;  2I4G A;  2FH7 A;  3QCG A;  1T48 A;  2Y1O A;  4QUN A;  3QCJ A;  1NWL A;  1A5Y A;  2DXP A;  2OOQ A;  3NRS A;  5AWX A;  3QKQ A;  4H34 A;  5KA7 A;  2F00 A;  3QCK A;  2UAG A;  4CVL A;  3QCB A;  1G1F A;  5IBS A;  2B07 A;  1KAV A;  1C88 A;  2GC5 A;  1YTN A;  1YWF A;  4GWF A;  2J16 A;  3V0J A;  5KA8 A;  3S4E A;  4OHI A;  3ZMQ A;  2I3R A;  1YGR A;  2I6M A;  3EZZ A;  3QCD A;  5MMZ B;  2A3K A;  1YN9 A;  1C84 A;  2GC6 A;  3O4T A;  2VTE A;  1LYV A;  2BGE A;  1D5R A;  3V0G A;  2QEP A;  3CWE A;  1YTW A;  2Y68 A;  1ZCL A;  1OET A;  2CM8 A;  1G1G A;  4I8N A;  4KYR A;  3F9A A;  4GFU A;  2B4S A;  3O3L A;  4RKK A;  2J17 A;  2GP0 A;  1EEO A;  3I36 A;  5KAC A;  3M4U A;  4WTY A;  1U25 A;  1I57 A;  2I3U A;  2WJP A;  3D9C A;  2HXP A;  4R0T A;  1V3A A;  5I6V A;  5HDE A;  1PA1 A;  5KA0 A;  4Z6B A;  2H4V A;  2HC1 A;  4BJO A;  1EEN A;  1ECV A;  3RZ2 A;  3S3H A;  2NT2 A;  4DGX A;  2NZ6 A;  3BLU A;  4QUM A;  2I1Y A;  2XPC A;  3LK7 A;  1LQF A;  1P31 A;  1MKP A;  4ERC A;  2AM1 A;  2B4P A;  1O5Z A;  2HY3 A;  1YTS A;  5K9W A;  5KAB A;  2ESB A;  2F6Z A;  1Q6P A;  4MBB A;  2HC2 A;  1E8C A;  1ONZ A;  1GWZ A;  1L8K A;  1WAX A;  2MBC A;  2Q05 A;  3QCH A;  1FPZ A;  2CNH A;  2I4H A;  3NME A;  2I42 A;  1ZCK A;  2JFG A;  4BUC A;  3UAG A;  2QBP A;  5KA2 A;  5K25 A;  2F71 A;  1BZJ A;  2XJA A;  3V0D A;  3ZV2 A;  1LAR A;  3ZL8 A;  1PTU A;  2I6P A;  3N2A A;  1OEV A;  2PQ5 A;  2PSZ A;  4RDD A;  1P3D A;  3BM8 A;  2I5X A;  1PXH A;  2PA5 A;  4R0S A;  1I9S A;  3I7Z A;  1PH0 A;  4Y2E A;  2CMB A;  5A5F A;  1BZC A;  1BZH A;  2E0T A;  1C87 A;  4OHD A;  5KAD A;  3ZM6 A;  4PVG A;  2A8B A;  2VEW A;  1J6U A;  2SHP A;  2QCJ A;  1Q6J A;  2CM7 A;  4HV4 A;  2GCB A;  4KYQ A;  3QCN A;  2AHS A;  4D3Q A;  4D3P A;  4QDI A;  4YAA A;  5BZZ A;  1PTV A;  1ZC0 A;  1RXD A;  2HNP A;  4C12 A;  3F81 A;  4RH5 A;  4DGP A;  2C46 A;  1XRI A;  3BLT A;  4TVV A;  4JMJ A;  4WOH A;  4GE5 A;  3QCC A;  3H2X A;  3QCL A;  3U96 A;  1OEM X;  4QAH A;  4GE6 A;  1ONY A;  2F6T A;  1Q1M A;  4CVM A;  3S3K A;  3D1Q A;  4WU3 A;  3V0E A;  4OHE A;  1Q6M A;  3QCZ A;  4JMK A;  3PYZ A;  2PBN A;  1U24 A;  3D42 A;  2QDM A;  4BPC A;  5KA9 A;  1W78 A;  2F46 A;  1WRM A;  1W7K A;  4OHL A;  3AWF A;  2CNE A;  3LJ8 A;  2I6O A;  3QCM A;  4GE2 A;  2I75 A;  2QCT A;  2VEU A;  1KAK A;  5IBM A;  4JNB A;  4J51 A;  1SUG A;  3F9B A;  2Y96 A;  4QF5 A;  2Y2F A;  1AAX A;  3ZM5 A;  3EB1 A;  2F6W A;  2CNI A;  1I9T A;  2QBQ A;  2F70 A;  3QKP A;  2I6J A;  2BZL A;  3A5K A;  1X24 A;  2NT7 A;  5KA4 A;  5GTJ A;  2BIJ A;  2ZN7 A;  3ZM3 A;  3I80 A;  3MMJ A;  2M3V A;  2CM3 A;  2CNG A;  2F6V A;  1JBV A;  3D44 A;  1PTY A;  1E0D A;  1Q6T A;  3OMH A;  2NLK A;  2JJD A;  5BZX A;  3HN7 A;  2VOR A;  3V0I A;  4JBC A;  5K23 A;  2VEY A;  1GQY A;  2OC3 A;  3ZM2 A;  2FJN A;  5LXQ B;  1OHD A;  3GXH A;  3N0A A;  3SR9 A;  1G7G A;  2GWO A;  3MOW A;  4HJP A;  2UUO A;  4Y14 A;  3D1O A;  1NNY A;  2HCM A;  2P6X A;  3QCE A;  3O5X A;  2H03 A;  1OEU A;  2PT0 A;  2NV5 A;  5KAA A;  1XXV A;  4GRZ A;  3V0H A;  3MVN A;  2GCA A;  5BUG A;  1NWE A;  2HB1 A;  2AM2 A;  1J4X A;  5J8R A;  2P4D A;  2CJZ A;  3V0F A;  4OHH A;  3AWE A;  1G1H A;  3F41 A;  1XXP A;  2QDP A;  2RF6 A;  2C7S A;  1JF7 A;  1YGU A;  2B4U A;  3EU0 A;  4GS0 A;  1VHR A;  1G4U S;  2H4K A;  2VOS A;  5EHR A;  2B49 A;  3B7O A;  4ICZ A;  1OHE A;  3S3F A;  4AZ1 A;  1G7F A;  4NX8 A;  4S0G A;  1U26 A;  4CVK A;  2BGD A;  4ZI4 A;  4HRF A;  5K9V A;  4QBE A;  2J16 B;  4QBW A;  1OEO X;  1UAG A;  4H1O A;  4B04 A;  1ZZW A;  2HVL A;  3O4S A;  2Y67 A;  2CMC A;  4NWF A;  4BUB A;  1NO6 A;  1C86 A;  1FQ1 A;  1FGS A;  4UAG A;  2B3O A;  5KA3 A;  1PYN A;  2AZR A;  1NL9 A;  1T49 A;  2Y66 A;  2WTZ A;  1G4W R;  2I4E A;  4GRY A;  2ZMM A;  5KA1 A;  4R30 A;  1GQQ A;  2OZ5 A;  2VEX A;  4D3R A;  4NWG A;  3CM3 A;  2NTA A;  4C13 A;  3PS5 A;  2R0B A;  2YDU A;  1OES A;  2IMG A;  1WCH A;  3D1H A;  3SME A;  2CMA A;  3QCF A;  2G6Z A;  3ZM0 A;  5K22 A;  4RI5 A;  2JFF A;  4RI4 A;  3GXG A;  4ZN5 A;  3RO1 A;  1Q6N A;  5EHP A;  2UUP A;  2JFH A; 
#chains in the Genus database with same CATH homology
 1T4J A;  4IKC A;  3S3E A;  2PI7 A;  4ZRT A;  1L8G A;  4WU2 A;  3QCI A;  1JLN A;  2QDC A;  3BRH A;  5M43 A;  5BX1 A;  1PA9 A;  2F6Y A;  2VEV A;  5K24 A;  1C85 A;  2I6I A;  1R6H A;  2BV5 A;  2F6F A;  1YZ4 A;  1QXK A;  4NYH A;  3RGQ A;  3ZMP A;  3EMU A;  4NND A;  2H02 A;  2CFV A;  1GFY A;  2Q47 A;  3F99 A;  4RHG A;  1QZ0 A;  2OUD A;  2G59 A;  1Q6S A;  1M3G A;  2H4G A;  1XM2 A;  3O4U A;  4GFV A;  3OLR A;  4RH9 A;  2QBR A;  3EAX A;  1FPR A;  4PYH A;  2CNF A;  3MOZ A;  2WGP A;  2FJM A;  2HNQ A;  3A5J A;  3AWG A;  4HJQ A;  1P15 A;  2CM2 A;  4QAP A;  4YR8 B;  2H04 A;  1YPT A;  2GJT A;  3S4O A;  3ZM1 A;  1RPM A;  2QBS A;  1C83 A;  1XBO A;  3RGO A;  1PTT A;  1YFO A;  2B4O A;  1OHC A;  4KI9 A;  1NZ7 A;  2I4G A;  2FH7 A;  3QCG A;  1T48 A;  4QUN A;  3QCJ A;  1NWL A;  1A5Y A;  2DXP A;  2OOQ A;  5AWX A;  3QKQ A;  4H34 A;  5KA7 A;  3QCK A;  3QCB A;  1G1F A;  5IBS A;  2B07 A;  1KAV A;  1C88 A;  1YTN A;  1YWF A;  4GWF A;  2J16 A;  3V0J A;  5KA8 A;  3S4E A;  4OHI A;  3ZMQ A;  2I3R A;  1YGR A;  2I6M A;  3QCD A;  3EZZ A;  5MMZ B;  2A3K A;  1YN9 A;  1C84 A;  3O4T A;  1LYV A;  2BGE A;  1D5R A;  3V0G A;  2QEP A;  3CWE A;  1YTW A;  1ZCL A;  1OET A;  2CM8 A;  1G1G A;  4I8N A;  4KYR A;  3F9A A;  4GFU A;  2B4S A;  3O3L A;  4RKK A;  2J17 A;  2GP0 A;  1EEO A;  3I36 A;  5KAC A;  3M4U A;  4WTY A;  1U25 A;  1I57 A;  2I3U A;  3D9C A;  2HXP A;  4R0T A;  1V3A A;  5I6V A;  5HDE A;  1PA1 A;  5KA0 A;  4Z6B A;  2H4V A;  2HC1 A;  4BJO A;  1EEN A;  1ECV A;  3RZ2 A;  3S3H A;  2NT2 A;  4DGX A;  2NZ6 A;  3BLU A;  4QUM A;  2I1Y A;  1LQF A;  1MKP A;  4ERC A;  2B4P A;  2HY3 A;  1YTS A;  5K9W A;  5KAB A;  2ESB A;  2F6Z A;  1Q6P A;  4MBB A;  2HC2 A;  1ONZ A;  1GWZ A;  1L8K A;  1WAX A;  2MBC A;  3QCH A;  2Q05 A;  1FPZ A;  2CNH A;  2I4H A;  3NME A;  2I42 A;  1ZCK A;  2QBP A;  5KA2 A;  5K25 A;  2F71 A;  1BZJ A;  3V0D A;  3ZV2 A;  1LAR A;  1PTU A;  2I6P A;  1OEV A;  2PQ5 A;  2PSZ A;  4RDD A;  3BM8 A;  2I5X A;  1PXH A;  2PA5 A;  4R0S A;  1I9S A;  3I7Z A;  1PH0 A;  4Y2E A;  2CMB A;  1BZC A;  1BZH A;  2E0T A;  1C87 A;  4OHD A;  5KAD A;  4PVG A;  2A8B A;  2VEW A;  2SHP A;  2QCJ A;  1Q6J A;  2CM7 A;  4KYQ A;  3QCN A;  2AHS A;  4D3Q A;  4D3P A;  4YAA A;  5BZZ A;  1PTV A;  1ZC0 A;  1RXD A;  2HNP A;  3F81 A;  4RH5 A;  4DGP A;  2C46 A;  1XRI A;  3BLT A;  4TVV A;  4JMJ A;  4WOH A;  4GE5 A;  3QCC A;  3H2X A;  3QCL A;  3U96 A;  1OEM X;  4QAH A;  4GE6 A;  1ONY A;  2F6T A;  1Q1M A;  3S3K A;  3D1Q A;  4WU3 A;  3V0E A;  4OHE A;  1Q6M A;  4JMK A;  2PBN A;  1U24 A;  3D42 A;  2QDM A;  4BPC A;  5KA9 A;  2F46 A;  1WRM A;  4OHL A;  3AWF A;  2CNE A;  3LJ8 A;  2I6O A;  3QCM A;  4GE2 A;  2I75 A;  2QCT A;  2VEU A;  1KAK A;  5IBM A;  4JNB A;  4J51 A;  1SUG A;  3F9B A;  2Y96 A;  2Y2F A;  1AAX A;  3EB1 A;  2F6W A;  2CNI A;  1I9T A;  2QBQ A;  2F70 A;  3QKP A;  2I6J A;  2BZL A;  3A5K A;  1X24 A;  2NT7 A;  5KA4 A;  5GTJ A;  2BIJ A;  2ZN7 A;  3ZM3 A;  3I80 A;  3MMJ A;  2M3V A;  2CM3 A;  2CNG A;  2F6V A;  3D44 A;  1PTY A;  1Q6T A;  3OMH A;  2NLK A;  2JJD A;  5BZX A;  3V0I A;  4JBC A;  5K23 A;  2VEY A;  2OC3 A;  3ZM2 A;  2FJN A;  5LXQ B;  1OHD A;  3GXH A;  3N0A A;  3SR9 A;  1G7G A;  2GWO A;  3MOW A;  4HJP A;  4Y14 A;  3D1O A;  1NNY A;  2HCM A;  2P6X A;  3QCE A;  3O5X A;  2H03 A;  1OEU A;  2PT0 A;  2NV5 A;  5KAA A;  1XXV A;  4GRZ A;  3V0H A;  5BUG A;  1NWE A;  2HB1 A;  1J4X A;  5J8R A;  2P4D A;  2CJZ A;  3V0F A;  4OHH A;  3AWE A;  1G1H A;  3F41 A;  1XXP A;  2QDP A;  2RF6 A;  2C7S A;  1JF7 A;  1YGU A;  2B4U A;  3EU0 A;  4GS0 A;  1VHR A;  1G4U S;  2H4K A;  5EHR A;  2B49 A;  3B7O A;  4ICZ A;  1OHE A;  3S3F A;  4AZ1 A;  1G7F A;  4NX8 A;  4S0G A;  1U26 A;  2BGD A;  4ZI4 A;  4HRF A;  5K9V A;  4QBE A;  2J16 B;  4QBW A;  1OEO X;  4H1O A;  4B04 A;  1ZZW A;  2HVL A;  3O4S A;  4NWF A;  2CMC A;  1NO6 A;  1C86 A;  1FQ1 A;  2B3O A;  5KA3 A;  1PYN A;  2AZR A;  1NL9 A;  1T49 A;  1G4W R;  2I4E A;  4GRY A;  2ZMM A;  5KA1 A;  4R30 A;  2OZ5 A;  2VEX A;  4D3R A;  4NWG A;  3CM3 A;  2NTA A;  3PS5 A;  2R0B A;  2YDU A;  1OES A;  2IMG A;  1WCH A;  3D1H A;  3SME A;  2CMA A;  3QCF A;  2G6Z A;  3ZM0 A;  5K22 A;  4RI5 A;  4RI4 A;  3GXG A;  4ZN5 A;  3RO1 A;  1Q6N A;  5EHP A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...