2I5DA

Crystal structure of human inosine triphosphate pyrophosphatase
Total Genus 68
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
195
structure length
195
Chain Sequence
HMAASLVGKKIVFVTGNAKKLEEVVQILGDKFPCTLVAQKIDLPEYQGEPDEISIQKCQEAVRQVQGPVLVEDTCLCFNALGGLPGPYIKWFLEKLKPEGLHQLLAGFEDKSAYALCTFALSTGDPSQPVRLFRGRTSGRIVAPRGCQDFGWDPCFQPDGYEQTYAEMPKAEKNAVSHRFRALLELQEYFGSLAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
molecule keywords inosine triphosphate pyrophosphohydrolase
publication title Structure of the orthorhombic form of human inosine triphosphate pyrophosphatase.
pubmed doi rcsb
source organism Homo sapiens
total genus 68
structure length 195
sequence length 195
ec nomenclature ec 3.6.1.9: Nucleotide diphosphatase.
pdb deposition date 2006-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01725 Ham1p_like Ham1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.950.10 Alpha Beta Alpha-Beta Complex Maf protein Maf protein 2i5dA00
2DVNA 2Q16A 1EX2A 2J4EA 1EXCA 2AMHA 3TQUA 1ZWYA 1VP2A 1K7KA 4HEBA 2CARA 4JHCA 1V7RA 2DVPA 2E5XA 4P0UA 2I5DA 3S86A 2PYUA 4P0EA 1B78A 2P5XA 4BNQA 4F95A 1U14A 2DVOA 2MJPA 2ZTIA 1U5WA 4OO0A 4LU1A 1ZNOA
chains in the Genus database with same CATH superfamily
2DVNA 2Q16A 4UUWA 1EX2A 2J4EA 4CT8A 1EXCA 2AMHA 3TQUA 1ZWYA 1VP2A 1K7KA 4HEBA 4CTAB 2CARA 4JHCA 1V7RA 2DVPA 2E5XA 4P0UA 4UUXA 5KOLA 2I5DA 3S86A 4UOCA 2PYUA 4P0EA 4CT9A 5KVKA 2A9SA 1B78A 2P5XA 4BNQA 4F95A 1U14A 4CTAA 2DVOA 2MJPA 2ZTIA 1U5WA 4OO0A 4LU1A 1ZNOA
chains in the Genus database with same CATH topology
2DVNA 2Q16A 1EX2A 2J4EA 1EXCA 2AMHA 3TQUA 1ZWYA 1VP2A 1K7KA 4HEBA 2CARA 4JHCA 1V7RA 2DVPA 2E5XA 4P0UA 2I5DA 3S86A 2PYUA 4P0EA 1B78A 2P5XA 4BNQA 4F95A 1U14A 2DVOA 2MJPA 2ZTIA 1U5WA 4OO0A 4LU1A 1ZNOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DVN A;  2Q16 A;  1EX2 A;  2J4E A;  1EXC A;  2AMH A;  3TQU A;  1ZWY A;  1VP2 A;  1K7K A;  4HEB A;  2CAR A;  4JHC A;  1V7R A;  2DVP A;  2E5X A;  4P0U A;  2I5D A;  3S86 A;  2PYU A;  4P0E A;  1B78 A;  2P5X A;  4BNQ A;  4F95 A;  1U14 A;  2DVO A;  2MJP A;  2ZTI A;  1U5W A;  4OO0 A;  4LU1 A;  1ZNO A; 
#chains in the Genus database with same CATH topology
 2DVN A;  2Q16 A;  4UUW A;  1EX2 A;  2J4E A;  4CT8 A;  1EXC A;  2AMH A;  3TQU A;  1ZWY A;  1VP2 A;  1K7K A;  4HEB A;  4CTA B;  2CAR A;  4JHC A;  1V7R A;  2DVP A;  2E5X A;  4P0U A;  4UUX A;  5KOL A;  2I5D A;  3S86 A;  4UOC A;  2PYU A;  4P0E A;  4CT9 A;  5KVK A;  2A9S A;  1B78 A;  2P5X A;  4BNQ A;  4F95 A;  1U14 A;  4CTA A;  2DVO A;  2MJP A;  2ZTI A;  1U5W A;  4OO0 A;  4LU1 A;  1ZNO A; 
#chains in the Genus database with same CATH homology
 2DVN A;  2Q16 A;  1EX2 A;  2J4E A;  1EXC A;  2AMH A;  3TQU A;  1ZWY A;  1VP2 A;  1K7K A;  4HEB A;  2CAR A;  4JHC A;  1V7R A;  2DVP A;  2E5X A;  4P0U A;  2I5D A;  3S86 A;  2PYU A;  4P0E A;  1B78 A;  2P5X A;  4BNQ A;  4F95 A;  1U14 A;  2DVO A;  2MJP A;  2ZTI A;  1U5W A;  4OO0 A;  4LU1 A;  1ZNO A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...