2I82A

Crystal structure of pseudouridine synthase rlua: indirect sequence readout through protein-induced rna structure
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
217
structure length
217
Chain Sequence
MENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPADF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure
pubmed doi rcsb
source organism Escherichia coli
molecule tags Lyase/rna
molecule keywords 5'-R(*GP*AP*GP*GP*GP*GP*AP*UP*UP*GP*AP*AP*AP*AP*UP*CP*CP*CP*
total genus 54
structure length 217
sequence length 217
chains with identical sequence B, C, D
ec nomenclature ec 5.4.99.28: tRNA pseudouridine(32) synthase.
pdb deposition date 2006-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00849 PseudoU_synth_2 RNA pseudouridylate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 2i82A00
4LGTA 1KSLA 3U28A 2AB4A 3DH3A 1ZL3A 1QYUA 1V9KA 1SGVA 2APOA 4LABA 3HJYA 3MQKA 2ISTA 3HJWA 1PRZA 3UAIA 2EY4A 3LWRA 1KSKA 3HAXA 3LWPA 1XPIA 1K8WA 3LWVA 1R3EA 2I82A 1ZE2A 2HVYA 3LWOA 2RFKA 1V9FA 2AUSA 1R3FA 3LWQA 1KSVA 1ZE1A
chains in the Genus database with same CATH superfamily
4LGTA 1KSLA 1SI7A 3U28A 2AB4A 3DH3A 1ZL3A 1SZWA 1QYUA 1V9KA 1SGVA 2APOA 1Z2ZA 4LABA 3HJYA 3MQKA 2ISTA 3HJWA 1PRZA 3UAIA 2EY4A 3LWRA 1KSKA 3HAXA 3LWPA 1XPIA 1K8WA 3LWVA 1R3EA 2I82A 1ZE2A 2HVYA 3LWOA 2RFKA 1SB7A 1V9FA 2AUSA 1R3FA 3LWQA 1KSVA 1ZE1A
chains in the Genus database with same CATH topology
4LGTA 1KSLA 1SI7A 3U28A 2AB4A 3DH3A 1ZL3A 1SZWA 1QYUA 1V9KA 1SGVA 2APOA 1Z2ZA 4LABA 3HJYA 3MQKA 2ISTA 3HJWA 1PRZA 3UAIA 2EY4A 3LWRA 1KSKA 3HAXA 3LWPA 1XPIA 1K8WA 3LWVA 1R3EA 2I82A 1ZE2A 2HVYA 3LWOA 2RFKA 1SB7A 1V9FA 2AUSA 1R3FA 3LWQA 1KSVA 1ZE1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LGT A;  1KSL A;  3U28 A;  2AB4 A;  3DH3 A;  1ZL3 A;  1QYU A;  1V9K A;  1SGV A;  2APO A;  4LAB A;  3HJY A;  3MQK A;  2IST A;  3HJW A;  1PRZ A;  3UAI A;  2EY4 A;  3LWR A;  1KSK A;  3HAX A;  3LWP A;  1XPI A;  1K8W A;  3LWV A;  1R3E A;  2I82 A;  1ZE2 A;  2HVY A;  3LWO A;  2RFK A;  1V9F A;  2AUS A;  1R3F A;  3LWQ A;  1KSV A;  1ZE1 A; 
#chains in the Genus database with same CATH topology
 4LGT A;  1KSL A;  1SI7 A;  3U28 A;  2AB4 A;  3DH3 A;  1ZL3 A;  1SZW A;  1QYU A;  1V9K A;  1SGV A;  2APO A;  1Z2Z A;  4LAB A;  3HJY A;  3MQK A;  2IST A;  3HJW A;  1PRZ A;  3UAI A;  2EY4 A;  3LWR A;  1KSK A;  3HAX A;  3LWP A;  1XPI A;  1K8W A;  3LWV A;  1R3E A;  2I82 A;  1ZE2 A;  2HVY A;  3LWO A;  2RFK A;  1SB7 A;  1V9F A;  2AUS A;  1R3F A;  3LWQ A;  1KSV A;  1ZE1 A; 
#chains in the Genus database with same CATH homology
 4LGT A;  1KSL A;  1SI7 A;  3U28 A;  2AB4 A;  3DH3 A;  1ZL3 A;  1SZW A;  1QYU A;  1V9K A;  1SGV A;  2APO A;  1Z2Z A;  4LAB A;  3HJY A;  3MQK A;  2IST A;  3HJW A;  1PRZ A;  3UAI A;  2EY4 A;  3LWR A;  1KSK A;  3HAX A;  3LWP A;  1XPI A;  1K8W A;  3LWV A;  1R3E A;  2I82 A;  1ZE2 A;  2HVY A;  3LWO A;  2RFK A;  1SB7 A;  1V9F A;  2AUS A;  1R3F A;  3LWQ A;  1KSV A;  1ZE1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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