2IB1A

Solution structure of p45 death domain
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
91
structure length
91
Chain Sequence
PQQQQEEVQRLLMMGEPAKGWQELAGHLGYQAEAVETMACDQMPAYTLLRNWAAQEGNRATLRVLEDALAAIGREDVVQVLSSPAESSSVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structure of p45 death domain
rcsb
molecule tags Apoptosis
source organism Mus musculus
molecule keywords Death domain containing membrane protein NRADD
total genus 20
structure length 91
sequence length 91
ec nomenclature
pdb deposition date 2006-09-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00531 Death Death domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2ib1A00
2MS8A 2NZ7A 2NSNA 2LWEA 3KATA 3YGSP 4RHWA 2IB1A 2KN6A 2DBFA 3MOPG 4M9ZA 1A1WA 1WH4A 1DGNA 2NAQA 3CL3A 2N97A 2LWDA 2DBGA 4ZBWA 4N1JA 1Z6TA 4DWNA 4F42A 1ICHA 4M9XA 4EWIA 1WMGA 2MS7A 2VGQA 2A5YB 4O9LA 2KM6A 2DO9A 3MOPA 4N1KA 4N1LA 4NQKA 2MB9A 2DBHA 2A9IA 4QOBA 2L6AA 2LS7A 1E3YA 3T6PA 2MN4A 4LWDA 3YGSC 2BBRA 1FADA 2M5VA 1NGRA 4A2WA 4RHWE 4O7QA 4D8OA 1PN5A 1YGOA 2DBDA 1CY5A 3CRDA 1WXPA 4FH0A 4F44A 1DDFA 4I16A 1A1ZA 2N80A 3LQQA 1D2ZB 1CWWA 2O71A 3J63A 4P4HI 4JUPA 2YU0A 1D2ZA 2N7ZA 1N3KA 2P1HA 1E41A 2YQFA 2N1FA 4E9MA 4O9FA 4M9SA 4IZ7B 1UCPA 3MOPK 2YGSA 2G7RA 4JQWA 4A2QA 4IZAB 3EZQB 3J6JA 4P4HA 2N00A 2BBZA 2YVIA 2F1SA 3EZQA 2N83A 4O6XA 2L9MA 1C15A 2MPCA 2OF5H 3QF2A 2GF5A 4UZ0A 2HM2Q 4IZ5E 2B1WA 2D96A 2OF5A 3LQRA
chains in the Genus database with same CATH superfamily
2MS8A 2NZ7A 2NSNA 2LWEA 3KATA 3YGSP 4RHWA 2IB1A 2KN6A 2DBFA 3MOPG 4M9ZA 1A1WA 1WH4A 1DGNA 2NAQA 3CL3A 2N97A 2LWDA 2DBGA 4ZBWA 4N1JA 2XV9A 1Z6TA 4DWNA 4F42A 1ICHA 4M9XA 4EWIA 1WMGA 2MS7A 2VGQA 2A5YB 4O9LA 2KM6A 2DO9A 3MOPA 4N1KA 4N1LA 4NQKA 2MB9A 2DBHA 2A9IA 4QOBA 2L6AA 2LS7A 1E3YA 3T6PA 2MN4A 4LWDA 3YGSC 2BBRA 1FADA 2M5VA 1NGRA 4A2WA 4RHWE 4O7QA 4D8OA 1PN5A 1YGOA 2DBDA 1CY5A 3CRDA 1WXPA 4FH0A 4F44A 1DDFA 4I16A 1A1ZA 2N80A 3LQQA 1D2ZB 1CWWA 2O71A 3J63A 4P4HI 4JUPA 2MJMA 2YU0A 1D2ZA 2N7ZA 1N3KA 2P1HA 1E41A 2YQFA 2N1FA 4E9MA 4O9FA 4M9SA 4IZ7B 1UCPA 3MOPK 2YGSA 2G7RA 4JQWA 4A2QA 4IZAB 3EZQB 3J6JA 4P4HA 2N00A 2BBZA 2YVIA 2F1SA 3EZQA 2N83A 4O6XA 2L9MA 1C15A 2MPCA 2OF5H 3QF2A 2GF5A 4UZ0A 2HM2Q 4IZ5E 2B1WA 2D96A 2OF5A 3LQRA
chains in the Genus database with same CATH topology
2MS8A 2NZ7A 2NSNA 2LWEA 3KATA 3YGSP 4RHWA 2IB1A 2KN6A 2DBFA 3MOPG 4M9ZA 1A1WA 1WH4A 1DGNA 2NAQA 3CL3A 2N97A 2LWDA 2DBGA 4ZBWA 4N1JA 2XV9A 1Z6TA 4DWNA 4F42A 1ICHA 4M9XA 4EWIA 1WMGA 2MS7A 2VGQA 2A5YB 4O9LA 2KM6A 2DO9A 3MOPA 4N1KA 4N1LA 4NQKA 2MB9A 2DBHA 2A9IA 4QOBA 2L6AA 2LS7A 1E3YA 3T6PA 2MN4A 4LWDA 3YGSC 2BBRA 1FADA 2M5VA 1NGRA 4A2WA 4RHWE 4O7QA 4D8OA 1PN5A 1YGOA 2DBDA 1CY5A 3CRDA 1WXPA 4FH0A 4F44A 1DDFA 4I16A 1A1ZA 2N80A 3LQQA 1D2ZB 1CWWA 2O71A 3J63A 4P4HI 4JUPA 2MJMA 2YU0A 1D2ZA 2N7ZA 1N3KA 2P1HA 1E41A 2YQFA 2N1FA 4E9MA 4O9FA 4M9SA 4IZ7B 1UCPA 3MOPK 2YGSA 2G7RA 4JQWA 4A2QA 4IZAB 3EZQB 3J6JA 4P4HA 2N00A 2BBZA 2YVIA 2F1SA 3EZQA 2N83A 4O6XA 2L9MA 1C15A 2MPCA 2OF5H 3QF2A 2GF5A 4UZ0A 2HM2Q 4IZ5E 2B1WA 2D96A 2OF5A 3LQRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MS8 A;  2NZ7 A;  2NSN A;  2LWE A;  3KAT A;  3YGS P;  4RHW A;  2IB1 A;  2KN6 A;  2DBF A;  3MOP G;  4M9Z A;  1A1W A;  1WH4 A;  1DGN A;  2NAQ A;  3CL3 A;  2N97 A;  2LWD A;  2DBG A;  4ZBW A;  4N1J A;  1Z6T A;  4DWN A;  4F42 A;  1ICH A;  4M9X A;  4EWI A;  1WMG A;  2MS7 A;  2VGQ A;  2A5Y B;  4O9L A;  2KM6 A;  2DO9 A;  3MOP A;  4N1K A;  4N1L A;  4NQK A;  2MB9 A;  2DBH A;  2A9I A;  4QOB A;  2L6A A;  2LS7 A;  1E3Y A;  3T6P A;  2MN4 A;  4LWD A;  3YGS C;  2BBR A;  1FAD A;  2M5V A;  1NGR A;  4A2W A;  4RHW E;  4O7Q A;  4D8O A;  1PN5 A;  1YGO A;  2DBD A;  1CY5 A;  3CRD A;  1WXP A;  4FH0 A;  4F44 A;  1DDF A;  4I16 A;  1A1Z A;  2N80 A;  3LQQ A;  1D2Z B;  1CWW A;  2O71 A;  3J63 A;  4P4H I;  4JUP A;  2YU0 A;  1D2Z A;  2N7Z A;  1N3K A;  2P1H A;  1E41 A;  2YQF A;  2N1F A;  4E9M A;  4O9F A;  4M9S A;  4IZ7 B;  1UCP A;  3MOP K;  2YGS A;  2G7R A;  4JQW A;  4A2Q A;  4IZA B;  3EZQ B;  3J6J A;  4P4H A;  2N00 A;  2BBZ A;  2YVI A;  2F1S A;  3EZQ A;  2N83 A;  4O6X A;  2L9M A;  1C15 A;  2MPC A;  2OF5 H;  3QF2 A;  2GF5 A;  4UZ0 A;  2HM2 Q;  4IZ5 E;  2B1W A;  2D96 A;  2OF5 A;  3LQR A; 
#chains in the Genus database with same CATH topology
 2MS8 A;  2NZ7 A;  2NSN A;  2LWE A;  3KAT A;  3YGS P;  4RHW A;  2IB1 A;  2KN6 A;  2DBF A;  3MOP G;  4M9Z A;  1A1W A;  1WH4 A;  1DGN A;  2NAQ A;  3CL3 A;  2N97 A;  2LWD A;  2DBG A;  4ZBW A;  4N1J A;  2XV9 A;  1Z6T A;  4DWN A;  4F42 A;  1ICH A;  4M9X A;  4EWI A;  1WMG A;  2MS7 A;  2VGQ A;  2A5Y B;  4O9L A;  2KM6 A;  2DO9 A;  3MOP A;  4N1K A;  4N1L A;  4NQK A;  2MB9 A;  2DBH A;  2A9I A;  4QOB A;  2L6A A;  2LS7 A;  1E3Y A;  3T6P A;  2MN4 A;  4LWD A;  3YGS C;  2BBR A;  1FAD A;  2M5V A;  1NGR A;  4A2W A;  4RHW E;  4O7Q A;  4D8O A;  1PN5 A;  1YGO A;  2DBD A;  1CY5 A;  3CRD A;  1WXP A;  4FH0 A;  4F44 A;  1DDF A;  4I16 A;  1A1Z A;  2N80 A;  3LQQ A;  1D2Z B;  1CWW A;  2O71 A;  3J63 A;  4P4H I;  4JUP A;  2MJM A;  2YU0 A;  1D2Z A;  2N7Z A;  1N3K A;  2P1H A;  1E41 A;  2YQF A;  2N1F A;  4E9M A;  4O9F A;  4M9S A;  4IZ7 B;  1UCP A;  3MOP K;  2YGS A;  2G7R A;  4JQW A;  4A2Q A;  4IZA B;  3EZQ B;  3J6J A;  4P4H A;  2N00 A;  2BBZ A;  2YVI A;  2F1S A;  3EZQ A;  2N83 A;  4O6X A;  2L9M A;  1C15 A;  2MPC A;  2OF5 H;  3QF2 A;  2GF5 A;  4UZ0 A;  2HM2 Q;  4IZ5 E;  2B1W A;  2D96 A;  2OF5 A;  3LQR A; 
#chains in the Genus database with same CATH homology
 2MS8 A;  2NZ7 A;  2NSN A;  2LWE A;  3KAT A;  3YGS P;  4RHW A;  2IB1 A;  2KN6 A;  2DBF A;  3MOP G;  4M9Z A;  1A1W A;  1WH4 A;  1DGN A;  2NAQ A;  3CL3 A;  2N97 A;  2LWD A;  2DBG A;  4ZBW A;  4N1J A;  2XV9 A;  1Z6T A;  4DWN A;  4F42 A;  1ICH A;  4M9X A;  4EWI A;  1WMG A;  2MS7 A;  2VGQ A;  2A5Y B;  4O9L A;  2KM6 A;  2DO9 A;  3MOP A;  4N1K A;  4N1L A;  4NQK A;  2MB9 A;  2DBH A;  2A9I A;  4QOB A;  2L6A A;  2LS7 A;  1E3Y A;  3T6P A;  2MN4 A;  4LWD A;  3YGS C;  2BBR A;  1FAD A;  2M5V A;  1NGR A;  4A2W A;  4RHW E;  4O7Q A;  4D8O A;  1PN5 A;  1YGO A;  2DBD A;  1CY5 A;  3CRD A;  1WXP A;  4FH0 A;  4F44 A;  1DDF A;  4I16 A;  1A1Z A;  2N80 A;  3LQQ A;  1D2Z B;  1CWW A;  2O71 A;  3J63 A;  4P4H I;  4JUP A;  2MJM A;  2YU0 A;  1D2Z A;  2N7Z A;  1N3K A;  2P1H A;  1E41 A;  2YQF A;  2N1F A;  4E9M A;  4O9F A;  4M9S A;  4IZ7 B;  1UCP A;  3MOP K;  2YGS A;  2G7R A;  4JQW A;  4A2Q A;  4IZA B;  3EZQ B;  3J6J A;  4P4H A;  2N00 A;  2BBZ A;  2YVI A;  2F1S A;  3EZQ A;  2N83 A;  4O6X A;  2L9M A;  1C15 A;  2MPC A;  2OF5 H;  3QF2 A;  2GF5 A;  4UZ0 A;  2HM2 Q;  4IZ5 E;  2B1W A;  2D96 A;  2OF5 A;  3LQR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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