2IBPA

Crystal structure of citrate synthase from pyrobaculum aerophilum
Total Genus 153
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
153
sequence length
407
structure length
407
Chain Sequence
EQTVQVKTTGKILQSPCGPIIHGLEDVLIKSTSISDIDGEKGILWYRGYRIEELARLSTYEEVSYLILYGRLPTKRELEDYINRMKKYRELHPATVEVIRNLAKAHPMFALEAAVAAEGAYDEDNQKLIEALSVGRYKAEEKELAYRIAEKLVAKMPTIVAYHYRFSRGLEVVRPRDDLGHAANFLYMMFGREPDPLASRGIDLYLILHADHEVPASTFAAHVVASTLSDLYSSVAAAIAALKGPLHGGANEMAVRNYLEIGTPAKAKEIVEAATKPGGPKLMGVGHRVYKAYDPRAKIFKEFSRDYVAKFGDPQNLFAIASAIEQEVLSHPYFQQRKLYPNVDFWSGIAFYYMGIPYEYFTPIFAMSRVVGWVAHVLEYWENNRIFRPRACYIGPHDLQYIPLEQR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of a thermophilic protein complex stabilized by topologically interlinked chains.
pubmed doi rcsb
molecule keywords Citrate synthase
molecule tags Transferase
source organism Pyrobaculum aerophilum
total genus 153
structure length 407
sequence length 407
chains with identical sequence B
ec nomenclature ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date 2006-09-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 2ibpA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 2ibpA01
1AL6A 2P2WA 3O8JA 1A59A 4JAEA 4G6BA 6CSCA 1O7XA 4JAGA 4XGHA 2CTSA 1AMZA 4YBOA 3TQGA 5CSCB 6CTSA 1OWBA 2C6XA 4TVMA 1IOMA 5CTSA 1NXGA 2CSCA 2R9EA 1VGPA 5CSCA 4CTSA 1CSIA 1CSSA 2IFCA 4JADA 1VGMA 2R26A 2IBPA 3HWKA 1CTSA 4CSCA 1CSRA 4JAFA 1OWCA 3MSUA 1AJ8A 3CSCA 3ENJA 1CSCA 1CSHA 1NXEA 2H12A 4E6YA 1IXEA
chains in the Genus database with same CATH superfamily
1AL6A 2P2WA 3O8JA 1A59A 4JAEA 4G6BA 4XGHA 1O7XA 4JAGA 6CSCA 2CTSA 1AMZA 4YBOA 3TQGA 5CSCB 6CTSA 1OWBA 2C6XA 4TVMA 1IOMA 5CTSA 1NXGA 2CSCA 2R9EA 1VGPA 5CSCA 4CTSA 1CSIA 1CSSA 2IFCA 4JADA 1VGMA 2R26A 2IBPA 3HWKA 1CTSA 4CSCA 1CSRA 4JAFA 1OWCA 3MSUA 1AJ8A 3CSCA 3ENJA 1CSCA 1CSHA 1NXEA 2H12A 4E6YA 1IXEA
chains in the Genus database with same CATH topology
1AL6A 2P2WA 3O8JA 1A59A 4JAEA 4G6BA 6CSCA 1O7XA 4JAGA 4XGHA 2CTSA 1AMZA 4YBOA 3TQGA 5CSCB 6CTSA 1OWBA 2C6XA 4TVMA 1IOMA 5CTSA 1NXGA 2CSCA 2R9EA 1VGPA 5CSCA 4CTSA 1CSIA 1CSSA 2IFCA 4JADA 1VGMA 2R26A 2IBPA 3HWKA 1CTSA 4CSCA 1CSRA 4JAFA 1OWCA 3MSUA 1AJ8A 3CSCA 3ENJA 1CSCA 1CSHA 1NXEA 2H12A 4E6YA 1IXEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AL6 A;  2P2W A;  3O8J A;  1A59 A;  4JAE A;  4G6B A;  6CSC A;  1O7X A;  4JAG A;  4XGH A;  2CTS A;  1AMZ A;  4YBO A;  3TQG A;  5CSC B;  6CTS A;  1OWB A;  2C6X A;  4TVM A;  1IOM A;  5CTS A;  1NXG A;  2CSC A;  2R9E A;  1VGP A;  5CSC A;  4CTS A;  1CSI A;  1CSS A;  2IFC A;  4JAD A;  1VGM A;  2R26 A;  2IBP A;  3HWK A;  1CTS A;  4CSC A;  1CSR A;  4JAF A;  1OWC A;  3MSU A;  1AJ8 A;  3CSC A;  3ENJ A;  1CSC A;  1CSH A;  1NXE A;  2H12 A;  4E6Y A;  1IXE A; 
#chains in the Genus database with same CATH topology
 1AL6 A;  2P2W A;  3O8J A;  1A59 A;  4JAE A;  4G6B A;  4XGH A;  1O7X A;  4JAG A;  6CSC A;  2CTS A;  1AMZ A;  4YBO A;  3TQG A;  5CSC B;  6CTS A;  1OWB A;  2C6X A;  4TVM A;  1IOM A;  5CTS A;  1NXG A;  2CSC A;  2R9E A;  1VGP A;  5CSC A;  4CTS A;  1CSI A;  1CSS A;  2IFC A;  4JAD A;  1VGM A;  2R26 A;  2IBP A;  3HWK A;  1CTS A;  4CSC A;  1CSR A;  4JAF A;  1OWC A;  3MSU A;  1AJ8 A;  3CSC A;  3ENJ A;  1CSC A;  1CSH A;  1NXE A;  2H12 A;  4E6Y A;  1IXE A; 
#chains in the Genus database with same CATH homology
 1AL6 A;  2P2W A;  3O8J A;  1A59 A;  4JAE A;  4G6B A;  6CSC A;  1O7X A;  4JAG A;  4XGH A;  2CTS A;  1AMZ A;  4YBO A;  3TQG A;  5CSC B;  6CTS A;  1OWB A;  2C6X A;  4TVM A;  1IOM A;  5CTS A;  1NXG A;  2CSC A;  2R9E A;  1VGP A;  5CSC A;  4CTS A;  1CSI A;  1CSS A;  2IFC A;  4JAD A;  1VGM A;  2R26 A;  2IBP A;  3HWK A;  1CTS A;  4CSC A;  1CSR A;  4JAF A;  1OWC A;  3MSU A;  1AJ8 A;  3CSC A;  3ENJ A;  1CSC A;  1CSH A;  1NXE A;  2H12 A;  4E6Y A;  1IXE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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