2IESA

Crystal structure of aquifex aeolicus lpxc complexed with pyrophosphate
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
267
structure length
267
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding of Uridine 5-Diphosphate in the Basic Patch of the Zinc Metalloenzyme Deacetylase LpxC and Implications for Substrate Binding
pubmed doi rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 85
structure length 267
sequence length 267
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2006-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 2iesA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 2iesA02
2VESA 3UHMA 3PS1A 4OZEA 4MQYA 3PS3A 4FW6A 3PS2A 5DRRA 2O3ZA 4IS9A 4U3BA 1XXEA 2J65A 4FW7A 2GO3A 4J3DA 5DRPA 4FW5A 4U3DA 5DRQA 3NZKA 1P42A 2IESA 4OKGA 4FW4A 2JT2A 3P3EA 3P3GA 4LCFA 4LCHA 4ISAA 4MDTA 5DROA 3P3CA 3U1YA 1YHCA 2GO4A 1YH8A 4FW3A 3P76A 2IERA 4LCGA
chains in the Genus database with same CATH superfamily
2UUCI 3PS1A 2V2ZA 4OO1B 1UDOA 2O3ZA 1XXEA 1Z0VA 3CDJA 5K36E 4DV4I 1IBME 3CDIA 4LF9I 4X62E 5DRPA 1N34E 3H4LA 4KQVA 2AJ4A 2PO0A 4DR3I 4I3HA 1N33I 2PNMA 4DPTA 1DARA 2CGEA 4ISAA 2WP8B 4WUCA 3K17A 3J7AM 1UDQA 4IZJA 4JV5E 5JEAB 2VQEE 2WNRA 2Z5EA 2NN6E 1U2RA 3M7ND 3L7ZB 1N0VC 2J65A 1MX0A 4BA1B 4DR2E 4AM3A 4NXMI 4DV7E 1NHHA 4LFBI 3OTOE 5IT9C 2IESA 4FW4A 2BR2A 4JG4A 2HKEA 4MDTA 3ZM7A 4XTJA 2ZM6I 2Q2EB 1H7UA 3PYFA 3JAMC 4N3OA 4JYAI 3WU4A 3J81Q 1Z0CA 5DRRA 2A2DA 3V5RA 2NN6C 4LF6E 3V2UC 1NHJA 4FW5A 2X36A 4ZVIA 2BM0A 3M85D 4NBQA 2C37A 3WU3A 2ZITA 2R3VA 1YHCA 4DR5E 3P06A 2UXCE 1Z59A 1Y4UA 2C38B 4JI4E 4Z7CA 2F1DA 1UDNA 4DV5I 1IBLI 4YHHI 4X66E 1E3HA 4DR7E 3T1YE 1HNZE 3PS2A 4DR1E 1HNZI 1ZM3A 3L7ZA 4DPWA 4DR6E 1ZM2A 2DEJA 4JI3I 4DR1I 1R6MA 1ZXNA 1VI7A 4MU3A 4KHPI 1WUUA 3GMEA 4LF4I 1Z0WA 3QT8A 3B4TA 4IZKB 1XMOI 2UUBE 2O1TA 4YY3I 2VESA 4LF7E 2C37B 4OO1F 1R6LA 4DPXA 4NXNE 3U1KA 4LF5I 4JI7E 1XNRE 2R42A 5DNXA 5IWAI 2IOPA 1Z0BA 1XMOE 4LFCI 2NN6F 5JEAC 4DV6I 1P42A 2BA1G 4LCHA 1B63A 2NPFA 4IZJD 4JI2E 2PO2B 5JEAF 2Z5CB 1IBKE 4MU0A 4PRVA 1EI1A 4LPFA 1KTVA 3UHMA 3LNUA 1KVKA 1FWKA 4BA1A 2C39B 1Z0TA 3Q6NA 5A2QC 2PO1B 4X64I 1UDSA 2PNLA 4QNJA 4X64E 1E3PA 2Z5BB 1IBLE 2BA0D 4R1FA 2A2CA 3GCMA 4JI4I 2JEBB 2O1UA 4B3ME 4Z7YA 4GKJE 2UXBE 4DV1E 4FWGA 1NZ0A 2O1VA 1FJGE 1FNMA 3WU5A 1YH8A 4MYUA 2UUAE 4DV0E 2IERA 2NN6B 3F0NA 2PO0B 1N0UA 3ZKBA 2Z5BA 1KIJA 4HY1A 4FW6A 2PO1A 4HXZA 4HYMA 3ZKDA 5FWKA 2X7IA 5C0XF 5LMUI 4DV3E 3OTOI 4DXLA 1FI4A 2CVEA 4LF9E 4LF7I 2UUBI 2JT2A 1HR0E 4FWHA 2VQFI 5K36B 4BA2A 2V8PA 4OO1C 2PNZB 2IOQA 2BV3A 2JE6B 1Z0EA 5LMNE 2JEAA 1Z5BA 4DR2I 3D4JA 4DV2E 5C0XB 5C0XE 4JI6E 1MU5A 1OJ4A 4JI0I 4DUYI 4DU8A 3QT6A 1EA6A 5K36F 2GO3A 4DUYE 4JI0E 1N33E 2LJPA 2UXBI 1I94E 5K36C 2DEIA 5ELWA 5EKWA 3B78A 3NZKA 2GS8A 4NXME 5IT9Q 4MU4A 4K0KI 4LOMA 4FW9A 1RR9A 3WU6A 1BKNA 2BA1D 2V2QA 3B82A 4MQYA 1B62A 2XEXA 4DV0I 1ZM9A 4JI5E 2HHHE 5K36D 4DUZI 3ZZUA 2EFGA 3J7AG 3HKMA 2HKJA 3P3CA 2JEAB 2WP8A 3J80C 2GO4A 1Z5AA 4FW3A 3M85G 3PYGA 4X65E 2HFSA 4BA2B 3GONA 3Q6MA 3GLLA 4DV7I 1XMQI 3PS3A 4URLA 4KHPE 2UU9I 4X65I 1HNXE 4FW7A 4USMA 4DR4I 4IFDF 5FLXQ 4UTGA 1VISA 4DR6I 2AE8A 4WUDA 4HACB 3U1YA 1ELOA 1HNWE 4HACA 4WUBA 1Z0GA 4OX9I 5IWAE 4LCGA 5EL9A 4X66I 4DU7A 4DV6E 4LFAE 3K1JA 4USKA 4JI8E 1XNQI 4DR5I 1FKAE 2UXCI 3QT7A 2ZM6E 4LF5E 4DUZE 1HK7A 3J80Q 4LF8I 5L3JA 4K0KE 2C39A 2NN6A 5LL6R 1QZRA 1Y5YA 1H7SA 1MG7A 1Z5CA 1KKHA 1OYRA 4PU9A 4IFDB 2F4VE 4OO1E 1H72C 3P76A 4B3RE 2JEBA 3T1YI 4DPUA 1FJGI 1USVA 4GKJI 4B3SE 2E1RA 4B3SI 4ED4A 4AQYE 3H1CA 5DRQA 2C38A 3M6AA 4DV5E 4B3RI 5A2QQ 4X62I 2WNRB 4LCFA 2BA0G 2PO2A 1OYSA 2J7KA 4DV3I 4MYTA 3Q1QA 4JI6I 2WW4A 4IFDA 1Y4SA 4DV2I 2O1WA 4P7AA 1N32I 2CZ9A 1Y6ZA 1H73A 2VQFE 1N36I 1HR0I 4IFDE 4DPYA 5FLXC 4LF6I 3HULA 5GMDA 1K47A 4IFDD 3ZZTA 4LF8E 5C0XC 4JI7I 4U3DA 1XNRI 5C0XA 4OO1A 3JAMQ 4IZKA 4AQYI 4JYAE 4LFBE 1XNQE 1PVGA 4JI1I 4DV4E 4JI8I 4OKGA 2BR2B 5GMEA 1OYPA 1NHIA 3LTOA 3T1HE 2UUCE 3QT5A 5JEAE 4UT4A 4B3TI 1A6FA 3DD6A 2UXDI 2VF3A 4IS9A 4JV5I 1UEKA 1IBKI 1D6TA 4B3MI 2UXDE 1ZM4A 2V2VA 4IFDC 1XHKA 4FN5A 4MU1A 3T1HI 2V34A 4DR7I 1S4EA 4YHHE 2NN6D 4DR3E 4RPFA 1ZXMA 1S16A 2PNZA 2CG9A 2HK3A 1IBMI 1RHYA 1XMQE 3M7NG 5LMUE 4OZEA 3B8HA 1H74A 4QNKA 1N34I 5JEAD 1Y60A 5BR8I 1PKPA 4FWDA 4LFAI 4LFCE 4J3DA 3CWVA 1RREA 2E5LE 2UUAI 2HHHI 2JE6A 1N32E 4OX9E 2BM1A 4JI3E 3P3GA 2HK2A 3P3EA 5DROA 2ZBKB 1HNXI 4NXNI 2UU9E 5JEAA 4IZJB 4AIDA 4DV1I 5BR8E 5DNLA 4GQUA 4YY3E 4U3BA 4B3TE 4OO1D 5C0XD 4M1KA 4DR4E 1USUA 3HJCA 4LF4E 1J5EI 3PYEA 4GKKI 4AIMA 3LPSA 3K85A 3ZZ0A 3PYDA 1HNWI 4EMDA 4JI1E 1I94I 4P52A 3PRYA 1J5EE 4GKKE 2GQ0A 2HFUA 4PRXA 5LMNI 4JI2I 4JI5I 2E5LI 3J81C 3KRNA 2F4VI 2OI2A 2VQEI 5K36A 2Z5CA 1FWLA 1N36E 1PIEA
chains in the Genus database with same CATH topology
2VESA 3UHMA 3PS1A 4OZEA 4MQYA 3PS3A 4FW6A 3PS2A 5DRRA 2O3ZA 4IS9A 4U3BA 1XXEA 2J65A 4FW7A 2GO3A 4J3DA 5DRPA 4FW5A 4U3DA 5DRQA 3NZKA 1P42A 2IESA 4OKGA 4FW4A 2JT2A 3P3EA 3P3GA 4LCFA 4LCHA 4ISAA 4MDTA 5DROA 3P3CA 3U1YA 1YHCA 2GO4A 1YH8A 4FW3A 3P76A 2IERA 4LCGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VES A;  3UHM A;  3PS1 A;  4OZE A;  4MQY A;  3PS3 A;  4FW6 A;  3PS2 A;  5DRR A;  2O3Z A;  4IS9 A;  4U3B A;  1XXE A;  2J65 A;  4FW7 A;  2GO3 A;  4J3D A;  5DRP A;  4FW5 A;  4U3D A;  5DRQ A;  3NZK A;  1P42 A;  2IES A;  4OKG A;  4FW4 A;  2JT2 A;  3P3E A;  3P3G A;  4LCF A;  4LCH A;  4ISA A;  4MDT A;  5DRO A;  3P3C A;  3U1Y A;  1YHC A;  2GO4 A;  1YH8 A;  4FW3 A;  3P76 A;  2IER A;  4LCG A; 
#chains in the Genus database with same CATH topology
 2UUC I;  3PS1 A;  2V2Z A;  4OO1 B;  1UDO A;  2O3Z A;  1XXE A;  1Z0V A;  3CDJ A;  5K36 E;  4DV4 I;  1IBM E;  3CDI A;  4LF9 I;  4X62 E;  5DRP A;  1N34 E;  3H4L A;  4KQV A;  2AJ4 A;  2PO0 A;  4DR3 I;  4I3H A;  1N33 I;  2PNM A;  4DPT A;  1DAR A;  2CGE A;  4ISA A;  2WP8 B;  4WUC A;  3K17 A;  3J7A M;  1UDQ A;  4IZJ A;  4JV5 E;  5JEA B;  2VQE E;  2WNR A;  2Z5E A;  2NN6 E;  1U2R A;  3M7N D;  3L7Z B;  1N0V C;  2J65 A;  1MX0 A;  4BA1 B;  4DR2 E;  4AM3 A;  4NXM I;  4DV7 E;  1NHH A;  4LFB I;  3OTO E;  5IT9 C;  2IES A;  4FW4 A;  2BR2 A;  4JG4 A;  2HKE A;  4MDT A;  3ZM7 A;  4XTJ A;  2ZM6 I;  2Q2E B;  1H7U A;  3PYF A;  3JAM C;  4N3O A;  4JYA I;  3WU4 A;  3J81 Q;  1Z0C A;  5DRR A;  2A2D A;  3V5R A;  2NN6 C;  4LF6 E;  3V2U C;  1NHJ A;  4FW5 A;  2X36 A;  4ZVI A;  2BM0 A;  3M85 D;  4NBQ A;  2C37 A;  3WU3 A;  2ZIT A;  2R3V A;  1YHC A;  4DR5 E;  3P06 A;  2UXC E;  1Z59 A;  1Y4U A;  2C38 B;  4JI4 E;  4Z7C A;  2F1D A;  1UDN A;  4DV5 I;  1IBL I;  4YHH I;  4X66 E;  1E3H A;  4DR7 E;  3T1Y E;  1HNZ E;  3PS2 A;  4DR1 E;  1HNZ I;  1ZM3 A;  3L7Z A;  4DPW A;  4DR6 E;  1ZM2 A;  2DEJ A;  4JI3 I;  4DR1 I;  1R6M A;  1ZXN A;  1VI7 A;  4MU3 A;  4KHP I;  1WUU A;  3GME A;  4LF4 I;  1Z0W A;  3QT8 A;  3B4T A;  4IZK B;  1XMO I;  2UUB E;  2O1T A;  4YY3 I;  2VES A;  4LF7 E;  2C37 B;  4OO1 F;  1R6L A;  4DPX A;  4NXN E;  3U1K A;  4LF5 I;  4JI7 E;  1XNR E;  2R42 A;  5DNX A;  5IWA I;  2IOP A;  1Z0B A;  1XMO E;  4LFC I;  2NN6 F;  5JEA C;  4DV6 I;  1P42 A;  2BA1 G;  4LCH A;  1B63 A;  2NPF A;  4IZJ D;  4JI2 E;  2PO2 B;  5JEA F;  2Z5C B;  1IBK E;  4MU0 A;  4PRV A;  1EI1 A;  4LPF A;  1KTV A;  3UHM A;  3LNU A;  1KVK A;  1FWK A;  4BA1 A;  2C39 B;  1Z0T A;  3Q6N A;  5A2Q C;  2PO1 B;  4X64 I;  1UDS A;  2PNL A;  4QNJ A;  4X64 E;  1E3P A;  2Z5B B;  1IBL E;  2BA0 D;  4R1F A;  2A2C A;  3GCM A;  4JI4 I;  2JEB B;  2O1U A;  4B3M E;  4Z7Y A;  4GKJ E;  2UXB E;  4DV1 E;  4FWG A;  1NZ0 A;  2O1V A;  1FJG E;  1FNM A;  3WU5 A;  1YH8 A;  4MYU A;  2UUA E;  4DV0 E;  2IER A;  2NN6 B;  3F0N A;  2PO0 B;  1N0U A;  3ZKB A;  2Z5B A;  1KIJ A;  4HY1 A;  4FW6 A;  2PO1 A;  4HXZ A;  4HYM A;  3ZKD A;  5FWK A;  2X7I A;  5C0X F;  5LMU I;  4DV3 E;  3OTO I;  4DXL A;  1FI4 A;  2CVE A;  4LF9 E;  4LF7 I;  2UUB I;  2JT2 A;  1HR0 E;  4FWH A;  2VQF I;  5K36 B;  4BA2 A;  2V8P A;  4OO1 C;  2PNZ B;  2IOQ A;  2BV3 A;  2JE6 B;  1Z0E A;  5LMN E;  2JEA A;  1Z5B A;  4DR2 I;  3D4J A;  4DV2 E;  5C0X B;  5C0X E;  4JI6 E;  1MU5 A;  1OJ4 A;  4JI0 I;  4DUY I;  4DU8 A;  3QT6 A;  1EA6 A;  5K36 F;  2GO3 A;  4DUY E;  4JI0 E;  1N33 E;  2LJP A;  2UXB I;  1I94 E;  5K36 C;  2DEI A;  5ELW A;  5EKW A;  3B78 A;  3NZK A;  2GS8 A;  4NXM E;  5IT9 Q;  4MU4 A;  4K0K I;  4LOM A;  4FW9 A;  1RR9 A;  3WU6 A;  1BKN A;  2BA1 D;  2V2Q A;  3B82 A;  4MQY A;  1B62 A;  2XEX A;  4DV0 I;  1ZM9 A;  4JI5 E;  2HHH E;  5K36 D;  4DUZ I;  3ZZU A;  2EFG A;  3J7A G;  3HKM A;  2HKJ A;  3P3C A;  2JEA B;  2WP8 A;  3J80 C;  2GO4 A;  1Z5A A;  4FW3 A;  3M85 G;  3PYG A;  4X65 E;  2HFS A;  4BA2 B;  3GON A;  3Q6M A;  3GLL A;  4DV7 I;  1XMQ I;  3PS3 A;  4URL A;  4KHP E;  2UU9 I;  4X65 I;  1HNX E;  4FW7 A;  4USM A;  4DR4 I;  4IFD F;  5FLX Q;  4UTG A;  1VIS A;  4DR6 I;  2AE8 A;  4WUD A;  4HAC B;  3U1Y A;  1ELO A;  1HNW E;  4HAC A;  4WUB A;  1Z0G A;  4OX9 I;  5IWA E;  4LCG A;  5EL9 A;  4X66 I;  4DU7 A;  4DV6 E;  4LFA E;  3K1J A;  4USK A;  4JI8 E;  1XNQ I;  4DR5 I;  1FKA E;  2UXC I;  3QT7 A;  2ZM6 E;  4LF5 E;  4DUZ E;  1HK7 A;  3J80 Q;  4LF8 I;  5L3J A;  4K0K E;  2C39 A;  2NN6 A;  5LL6 R;  1QZR A;  1Y5Y A;  1H7S A;  1MG7 A;  1Z5C A;  1KKH A;  1OYR A;  4PU9 A;  4IFD B;  2F4V E;  4OO1 E;  1H72 C;  3P76 A;  4B3R E;  2JEB A;  3T1Y I;  4DPU A;  1FJG I;  1USV A;  4GKJ I;  4B3S E;  2E1R A;  4B3S I;  4ED4 A;  4AQY E;  3H1C A;  5DRQ A;  2C38 A;  3M6A A;  4DV5 E;  4B3R I;  5A2Q Q;  4X62 I;  2WNR B;  4LCF A;  2BA0 G;  2PO2 A;  1OYS A;  2J7K A;  4DV3 I;  4MYT A;  3Q1Q A;  4JI6 I;  2WW4 A;  4IFD A;  1Y4S A;  4DV2 I;  2O1W A;  4P7A A;  1N32 I;  2CZ9 A;  1Y6Z A;  1H73 A;  2VQF E;  1N36 I;  1HR0 I;  4IFD E;  4DPY A;  5FLX C;  4LF6 I;  3HUL A;  5GMD A;  1K47 A;  4IFD D;  3ZZT A;  4LF8 E;  5C0X C;  4JI7 I;  4U3D A;  1XNR I;  5C0X A;  4OO1 A;  3JAM Q;  4IZK A;  4AQY I;  4JYA E;  4LFB E;  1XNQ E;  1PVG A;  4JI1 I;  4DV4 E;  4JI8 I;  4OKG A;  2BR2 B;  5GME A;  1OYP A;  1NHI A;  3LTO A;  3T1H E;  2UUC E;  3QT5 A;  5JEA E;  4UT4 A;  4B3T I;  1A6F A;  3DD6 A;  2UXD I;  2VF3 A;  4IS9 A;  4JV5 I;  1UEK A;  1IBK I;  1D6T A;  4B3M I;  2UXD E;  1ZM4 A;  2V2V A;  4IFD C;  1XHK A;  4FN5 A;  4MU1 A;  3T1H I;  2V34 A;  4DR7 I;  1S4E A;  4YHH E;  2NN6 D;  4DR3 E;  4RPF A;  1ZXM A;  1S16 A;  2PNZ A;  2CG9 A;  2HK3 A;  1IBM I;  1RHY A;  1XMQ E;  3M7N G;  5LMU E;  4OZE A;  3B8H A;  1H74 A;  4QNK A;  1N34 I;  5JEA D;  1Y60 A;  5BR8 I;  1PKP A;  4FWD A;  4LFA I;  4LFC E;  4J3D A;  3CWV A;  1RRE A;  2E5L E;  2UUA I;  2HHH I;  2JE6 A;  1N32 E;  4OX9 E;  2BM1 A;  4JI3 E;  3P3G A;  2HK2 A;  3P3E A;  5DRO A;  2ZBK B;  1HNX I;  4NXN I;  2UU9 E;  5JEA A;  4IZJ B;  4AID A;  4DV1 I;  5BR8 E;  5DNL A;  4GQU A;  4YY3 E;  4U3B A;  4B3T E;  4OO1 D;  5C0X D;  4M1K A;  4DR4 E;  1USU A;  3HJC A;  4LF4 E;  1J5E I;  3PYE A;  4GKK I;  4AIM A;  3LPS A;  3K85 A;  3ZZ0 A;  3PYD A;  1HNW I;  4EMD A;  4JI1 E;  1I94 I;  4P52 A;  3PRY A;  1J5E E;  4GKK E;  2GQ0 A;  2HFU A;  4PRX A;  5LMN I;  4JI2 I;  4JI5 I;  2E5L I;  3J81 C;  3KRN A;  2F4V I;  2OI2 A;  2VQE I;  5K36 A;  2Z5C A;  1FWL A;  1N36 E;  1PIE A; 
#chains in the Genus database with same CATH homology
 2VES A;  3UHM A;  3PS1 A;  4OZE A;  4MQY A;  3PS3 A;  4FW6 A;  3PS2 A;  5DRR A;  2O3Z A;  4IS9 A;  4U3B A;  1XXE A;  2J65 A;  4FW7 A;  2GO3 A;  4J3D A;  5DRP A;  4FW5 A;  4U3D A;  5DRQ A;  3NZK A;  1P42 A;  2IES A;  4OKG A;  4FW4 A;  2JT2 A;  3P3E A;  3P3G A;  4LCF A;  4LCH A;  4ISA A;  4MDT A;  5DRO A;  3P3C A;  3U1Y A;  1YHC A;  2GO4 A;  1YH8 A;  4FW3 A;  3P76 A;  2IER A;  4LCG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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