2IHBB

Crystal structure of the heterodimeric complex of human rgs10 and activated gi alpha 3
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
122
structure length
111
Chain Sequence
LKSTAKWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKMQDKTQMQEKAKEIYMTFLSSKASSQVNVEGPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Guanine nucleotide-binding protein G(k) subunit alpha
publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
source organism Homo sapiens
total genus 38
structure length 111
sequence length 122
ec nomenclature
pdb deposition date 2006-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2ihbB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2ihbB01
2IHDA 2OWIA 3NYNA 1FQJB 2EBZA 3NYOA 4MK0A 3UZTA 2IK8B 4TNDA 3V5WA 1FQKB 2CRPA 2BT2A 1AGRE 2DLVA 3KRXA 2JNUA 2GTPC 2BCJA 1DK8A 3PSCA 1CMZA 5DO9B 1EZTA 3CIKA 4EKDB 3C7KB 5HE2A 2BV1A 1OMWA 2IHBB 3PVUA 1EZYA 4TNBA 2D9JA 3KRWA 5HE1A 2JM5A 3C7LA 2AF0A 2ODEB 3PVWA 4PNKA 1FQIA 5HE3A 1EMUA 5HE0A 2V4ZB 2OJ4A
chains in the Genus database with same CATH superfamily
3I5QA 2IHDA 2OWIA 3NYNA 1FQJB 2EBZA 3NYOA 4MK0A 3UZTA 2IK8B 4TNDA 3V5WA 1FQKB 2CRPA 2BT2A 1AGRE 2DLVA 3KRXA 2JNUA 2GTPC 2BCJA 1DK8A 3PSCA 1CMZA 5DO9B 1EZTA 3CIKA 4EKDB 3C7KB 5HE2A 2BV1A 1OMWA 2IHBB 3PVUA 5REQB 1EZYA 4TNBA 2D9JA 3KRWA 5HE1A 2JM5A 3QYFA 3C7LA 4HTEA 2AF0A 2ODEB 3PVWA 4PNKA 1FQIA 5HE3A 1EMUA 5HE0A 2V4ZB 2OJ4A
chains in the Genus database with same CATH topology
2IHDA 2OWIA 3NYNA 1FQJB 2EBZA 3NYOA 4MK0A 3UZTA 2IK8B 4TNDA 3V5WA 1FQKB 2CRPA 2BT2A 1AGRE 2DLVA 3KRXA 2JNUA 2GTPC 2BCJA 1DK8A 3PSCA 1CMZA 5DO9B 1EZTA 3CIKA 4EKDB 3C7KB 5HE2A 2BV1A 1OMWA 2IHBB 3PVUA 5REQB 1EZYA 4TNBA 2D9JA 3KRWA 5HE1A 2JM5A 3QYFA 3C7LA 2AF0A 2ODEB 3PVWA 4PNKA 1FQIA 5HE3A 1EMUA 5HE0A 2V4ZB 2OJ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IHD A;  2OWI A;  3NYN A;  1FQJ B;  2EBZ A;  3NYO A;  4MK0 A;  3UZT A;  2IK8 B;  4TND A;  3V5W A;  1FQK B;  2CRP A;  2BT2 A;  1AGR E;  2DLV A;  3KRX A;  2JNU A;  2GTP C;  2BCJ A;  1DK8 A;  3PSC A;  1CMZ A;  5DO9 B;  1EZT A;  3CIK A;  4EKD B;  3C7K B;  5HE2 A;  2BV1 A;  1OMW A;  2IHB B;  3PVU A;  1EZY A;  4TNB A;  2D9J A;  3KRW A;  5HE1 A;  2JM5 A;  3C7L A;  2AF0 A;  2ODE B;  3PVW A;  4PNK A;  1FQI A;  5HE3 A;  1EMU A;  5HE0 A;  2V4Z B;  2OJ4 A; 
#chains in the Genus database with same CATH topology
 3I5Q A;  2IHD A;  2OWI A;  3NYN A;  1FQJ B;  2EBZ A;  3NYO A;  4MK0 A;  3UZT A;  2IK8 B;  4TND A;  3V5W A;  1FQK B;  2CRP A;  2BT2 A;  1AGR E;  2DLV A;  3KRX A;  2JNU A;  2GTP C;  2BCJ A;  1DK8 A;  3PSC A;  1CMZ A;  5DO9 B;  1EZT A;  3CIK A;  4EKD B;  3C7K B;  5HE2 A;  2BV1 A;  1OMW A;  2IHB B;  3PVU A;  5REQ B;  1EZY A;  4TNB A;  2D9J A;  3KRW A;  5HE1 A;  2JM5 A;  3QYF A;  3C7L A;  4HTE A;  2AF0 A;  2ODE B;  3PVW A;  4PNK A;  1FQI A;  5HE3 A;  1EMU A;  5HE0 A;  2V4Z B;  2OJ4 A; 
#chains in the Genus database with same CATH homology
 2IHD A;  2OWI A;  3NYN A;  1FQJ B;  2EBZ A;  3NYO A;  4MK0 A;  3UZT A;  2IK8 B;  4TND A;  3V5W A;  1FQK B;  2CRP A;  2BT2 A;  1AGR E;  2DLV A;  3KRX A;  2JNU A;  2GTP C;  2BCJ A;  1DK8 A;  3PSC A;  1CMZ A;  5DO9 B;  1EZT A;  3CIK A;  4EKD B;  3C7K B;  5HE2 A;  2BV1 A;  1OMW A;  2IHB B;  3PVU A;  5REQ B;  1EZY A;  4TNB A;  2D9J A;  3KRW A;  5HE1 A;  2JM5 A;  3QYF A;  3C7L A;  2AF0 A;  2ODE B;  3PVW A;  4PNK A;  1FQI A;  5HE3 A;  1EMU A;  5HE0 A;  2V4Z B;  2OJ4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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