2IHBB

Crystal structure of the heterodimeric complex of human rgs10 and activated gi alpha 3
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
122
structure length
111
Chain Sequence
LKSTAKWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKMQDKTQMQEKAKEIYMTFLSSKASSQVNVEGPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Guanine nucleotide-binding protein G(k) subunit alpha
total genus 38
structure length 111
sequence length 122
ec nomenclature
pdb deposition date 2006-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2ihbB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2ihbB01
5HE1A 1FQJB 2V4ZB 5HE0A 1FQKB 2BV1A 3CIKA 1EMUA 3UZTA 2OWIA 3PSCA 3V5WA 2IHDA 2IHBB 2OJ4A 2IK8B 3C7KB 2EBZA 3NYNA 4PNKA 2D9JA 2JNUA 2DLVA 4TNDA 1FQIA 3KRWA 3C7LA 1EZTA 3NYOA 3PVWA 4TNBA 2GTPC 2AF0A 2BCJA 5HE3A 3KRXA 1AGRE 5DO9B 2ODEB 4MK0A 5HE2A 2JM5A 1EZYA 2CRPA 1CMZA 1DK8A 3PVUA 1OMWA 2BT2A 4EKDB
chains in the Genus database with same CATH superfamily
5HE1A 1FQJB 2V4ZB 5HE0A 1FQKB 2BV1A 3CIKA 1EMUA 3UZTA 2OWIA 3I5QA 3PSCA 3V5WA 5REQB 2IHDA 2IHBB 2OJ4A 2IK8B 3C7KB 2EBZA 3NYNA 4PNKA 2D9JA 2JNUA 2DLVA 4TNDA 1FQIA 3KRWA 3QYFA 3C7LA 1EZTA 3NYOA 3PVWA 4TNBA 2GTPC 2AF0A 2BCJA 5HE3A 3KRXA 1AGRE 5DO9B 2ODEB 4MK0A 5HE2A 2JM5A 1EZYA 2CRPA 1CMZA 1DK8A 3PVUA 1OMWA 4HTEA 2BT2A 4EKDB
chains in the Genus database with same CATH topology
5HE1A 1FQJB 2V4ZB 5HE0A 1FQKB 2BV1A 3CIKA 1EMUA 3UZTA 2OWIA 3PSCA 3V5WA 5REQB 2IHDA 2IHBB 2OJ4A 2IK8B 3C7KB 2EBZA 3NYNA 4PNKA 2D9JA 2JNUA 2DLVA 4TNDA 1FQIA 3KRWA 3QYFA 3C7LA 1EZTA 3NYOA 3PVWA 4TNBA 2GTPC 2AF0A 2BCJA 5HE3A 3KRXA 1AGRE 5DO9B 2ODEB 4MK0A 5HE2A 2JM5A 1EZYA 2CRPA 1CMZA 1DK8A 3PVUA 1OMWA 2BT2A 4EKDB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HE1 A;  1FQJ B;  2V4Z B;  5HE0 A;  1FQK B;  2BV1 A;  3CIK A;  1EMU A;  3UZT A;  2OWI A;  3PSC A;  3V5W A;  2IHD A;  2IHB B;  2OJ4 A;  2IK8 B;  3C7K B;  2EBZ A;  3NYN A;  4PNK A;  2D9J A;  2JNU A;  2DLV A;  4TND A;  1FQI A;  3KRW A;  3C7L A;  1EZT A;  3NYO A;  3PVW A;  4TNB A;  2GTP C;  2AF0 A;  2BCJ A;  5HE3 A;  3KRX A;  1AGR E;  5DO9 B;  2ODE B;  4MK0 A;  5HE2 A;  2JM5 A;  1EZY A;  2CRP A;  1CMZ A;  1DK8 A;  3PVU A;  1OMW A;  2BT2 A;  4EKD B; 
#chains in the Genus database with same CATH topology
 5HE1 A;  1FQJ B;  2V4Z B;  5HE0 A;  1FQK B;  2BV1 A;  3CIK A;  1EMU A;  3UZT A;  2OWI A;  3I5Q A;  3PSC A;  3V5W A;  5REQ B;  2IHD A;  2IHB B;  2OJ4 A;  2IK8 B;  3C7K B;  2EBZ A;  3NYN A;  4PNK A;  2D9J A;  2JNU A;  2DLV A;  4TND A;  1FQI A;  3KRW A;  3QYF A;  3C7L A;  1EZT A;  3NYO A;  3PVW A;  4TNB A;  2GTP C;  2AF0 A;  2BCJ A;  5HE3 A;  3KRX A;  1AGR E;  5DO9 B;  2ODE B;  4MK0 A;  5HE2 A;  2JM5 A;  1EZY A;  2CRP A;  1CMZ A;  1DK8 A;  3PVU A;  1OMW A;  4HTE A;  2BT2 A;  4EKD B; 
#chains in the Genus database with same CATH homology
 5HE1 A;  1FQJ B;  2V4Z B;  5HE0 A;  1FQK B;  2BV1 A;  3CIK A;  1EMU A;  3UZT A;  2OWI A;  3PSC A;  3V5W A;  5REQ B;  2IHD A;  2IHB B;  2OJ4 A;  2IK8 B;  3C7K B;  2EBZ A;  3NYN A;  4PNK A;  2D9J A;  2JNU A;  2DLV A;  4TND A;  1FQI A;  3KRW A;  3QYF A;  3C7L A;  1EZT A;  3NYO A;  3PVW A;  4TNB A;  2GTP C;  2AF0 A;  2BCJ A;  5HE3 A;  3KRX A;  1AGR E;  5DO9 B;  2ODE B;  4MK0 A;  5HE2 A;  2JM5 A;  1EZY A;  2CRP A;  1CMZ A;  1DK8 A;  3PVU A;  1OMW A;  2BT2 A;  4EKD B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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